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550 results on '"Alison Duncan"'

1. Concomitant Transapical Aortic/Mitral Transcatheter Valve Replacement for Severe Aortic Stenosis and Mitral Annular Calcification

Author

Alicja Zientara, MD, Alison Duncan, MB, BS, PhD, Ee Ling Heng, MBBS, BS, PhD, and Cesare Quarto, MD, PhD

Subjects
mitral annular calcification, rheumatic valve disease, transcatheter aortic valve replacement, transcatheter mitral valve replacement, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Mitral regurgitation (MR) associated with mitral annular calcification (MAC) is surgically challenging, and valve-in-MAC procedures using transcatheter aortic valve replacement (TAVR) devices have poor outcomes. Transcatheter mitral valve replacement (TMVR) may be an option. Concomitant TAVR and TMVR are limited to 2 reports. We describe the first case of concomitant TAVR and TMVR-in-MAC procedures. (Level of Difficulty: Advanced.)

Published
2023
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2. Midterm Outcomes in Patients With Aortic Stenosis Treated With Contemporary Balloon‐Expandable and Self‐Expanding Valves: Does Valve Size Have an Impact on Outcome?

Author

Konstantinos Kalogeras, Richard J. Jabbour, Radoslaw Pracon, Tito Kabir, Joanne Shannon, Alison Duncan, Cesare Quarto, Ee‐Ling Heng, Hazim Rahbi, Evangelos Oikonomou, Efstratios Katsianos, Niket Patel, Navin Chandra, Michael‐Andrew Vavuranakis, Suzane Cadiz, Maria Bougiakli, Robert D. Smith, Gerasimos Siasos, Manolis Vavuranakis, Simon Davies, Miles Dalby, and Vasileios Panoulas

Subjects
balloon expandable, paravalvular regurgitation, self‐expanding, small transcatheter heart valve, transcatheter aortic valve implantation, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Background No data currently exist comparing the contemporary iterations of balloon‐expandable (BE) Edwards SAPIEN 3/Ultra and the self‐expanding (SE) Medtronic Evolut PRO/R34 valves. The aim of the study was the comparison of these transcatheter heart valves with emphasis on patients with small aortic annulus. Methods and Results In this retrospective registry, periprocedural outcomes and midterm all‐cause mortality were analyzed. A total of 1673 patients (917 SE versus 756 BE) were followed up for a median of 15 months. A total of 194 patients died (11.6%) during follow‐up. SE and BE groups showed similar survival at 1 (92.6% versus 90.6%) and 3 (80.3% versus 85.2%) years (Plog‐rank=0.136). Compared with the BE group, patients treated with the SE device had lower peak (16.3±8 mm Hg SE versus 21.9±8 mm Hg BE) and mean (8.8±5 mm Hg SE versus 11.5±5 mm Hg BE) gradients at discharge. Conversely, the BE group demonstrated lower rates of at least moderate paravalvular regurgitation postoperatively (5.6% versus 0.7% for SE and BE valves, respectively; P

Published
2023
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3. The health effects of soy: A reference guide for health professionals

Author

Mark Messina, Alison Duncan, Virginia Messina, Heidi Lynch, Jessica Kiel, and John W. Erdman

Subjects
soyfoods, counseling, patients, isoflavones, review, protein, Nutrition. Foods and food supply, TX341-641
Abstract

Soy is a hotly debated and widely discussed topic in the field of nutrition. However, health practitioners may be ill-equipped to counsel clients and patients about the use of soyfoods because of the enormous, and often contradictory, amount of research that has been published over the past 30 years. As interest in plant-based diets increases, there will be increased pressure for practitioners to gain a working knowledge of this area. The purpose of this review is to provide concise literature summaries (400–500 words) along with a short perspective on the current state of knowledge of a wide range of topics related to soy, from the cholesterol-lowering effects of soy protein to the impact of isoflavones on breast cancer risk. In addition to the literature summaries, general background information on soyfoods, soy protein, and isoflavones is provided. This analysis can serve as a tool for health professionals to be used when discussing soyfoods with their clients and patients.

Published
2022
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5. Improved right ventricular function following transapical transcatheter mitral valve implantation for severe mitral regurgitation

Author

Sara Hungerford, Nicole Bart, Paul Jansz, Sharon Kay, Sam Emmanuel, Mayooran Namasivayam, Gry Dahle, Alison Duncan, Christopher Hayward, and David W.M. Muller

Subjects
Echocardiography, Mitral regurgitation, Myocardial strain, Right ventricular function, Transcatheter mitral valve implantation, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Background: Transapical transcatheter mitral valve implantation (TMVI) may be a therapeutic option for patients with severe mitral regurgitation (MR) excluded from cardiac surgery due to excessive risk. Exclusion criteria frequently include pulmonary hypertension and right ventricular (RV) dysfunction. The effect of TMVI on RV function has not previously been well-characterized. The aim of this study was to examine the procedural and 3-month impact of TMVI on RV hemodynamics and function. Methods: This was a multi-center, retrospective, observational cohort study of patients with >3+MR undergoing TMVI. Pre- and post-TMVI hemodynamics were assessed with right heart catheterization. RV function was assessed at baseline, pre-discharge and at 3-months by echocardiography. Results: Forty-six patients (age 72±9 years; 34 men) with ≥3+MR underwent TMVI over a 5-year period. Successful device implantation was achieved in all patients with abolition of MR (p < 0.001) and reduction in left-ventricular end-diastolic volume (p = 0.001). RV stroke work index (RVSWI) increased intra-operatively (7 ± 4 g/m/beat/m2 vs 11 ± 5 g/m/beat/m2; p < 0.001). At 3-months there were reductions in severity of tricuspid regurgitation (TR) (p < 0.001) and pulmonary artery systolic pressure (PASP) (49 ± 16 mmHg vs 36 ± 12 mmHg; p < 0.001), and improvements in RV fractional area change (28 ± 7% vs 34 ± 9%, p

Published
2021
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7. INDEX

Author

Richard S. Dunn, Mary Maples Dunn, Craig W. Horle, Alison Duncan Hirsch, Marianne S. Wokeck, and Joy Wiltenburg

Published
2016

10. APPENDIX

Author

Richard S. Dunn, Mary Maples Dunn, Craig W. Horle, Alison Duncan Hirsch, Marianne S. Wokeck, and Joy Wiltenburg

Published
2016

20. 179. To Queen Anne, c. 31 July 1710

Author

Richard S. Dunn, Mary Maples Dunn, Craig W. Horle, Alison Duncan Hirsch, Marianne S. Wokeck, and Joy Wiltenburg

Published
2016

26. 197. To James Logan, 15 August 1712

Author

Richard S. Dunn, Mary Maples Dunn, Craig W. Horle, Alison Duncan Hirsch, Marianne S. Wokeck, and Joy Wiltenburg

Published
2016

28. THE CLOSING YEARS, 1713–1718

Author

Richard S. Dunn, Mary Maples Dunn, Craig W. Horle, Alison Duncan Hirsch, Marianne S. Wokeck, and Joy Wiltenburg

Published
2016

31. 194. From James Logan, 12 June 1712

Author

Richard S. Dunn, Mary Maples Dunn, Craig W. Horle, Alison Duncan Hirsch, Marianne S. Wokeck, and Joy Wiltenburg

Published
2016

32. 192. To James Logan, 7 March 1712

Author

Richard S. Dunn, Mary Maples Dunn, Craig W. Horle, Alison Duncan Hirsch, Marianne S. Wokeck, and Joy Wiltenburg

Published
2016

33. 195. To James Logan, 24 July 1712

Author

Richard S. Dunn, Mary Maples Dunn, Craig W. Horle, Alison Duncan Hirsch, Marianne S. Wokeck, and Joy Wiltenburg

Published
2016

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