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Excitation functions based on level density were calculated for proton-induced on yttrium-89 using the TALYS-1.8 code. Hence, production cross-section of the 89 Y(p,x) 86,88,89g Zr, 86g,87g,88g Y, 85g Sr, and 84g Rb were computed up to 50 MeV. In this study, the constant temperature model alongside the Fermi Gas model (CGCM) was employed as a default model. For this reason, the a-parameter as an essential parameter in the Fermi Gas formula was modified to obtain the best result. Besides, the Back-shifted Fermi Gas Model (BSFGM) and the Generalized Superfluid Model (GSM) are presented to the deliberation. The outcomes of cross-sections were compared with the experimental data approaching regarding desired consequences., (Copyright © 2019 Elsevier Ltd. All rights reserved.)