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2. Supplementary Methods from A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2–Positive Metastatic Breast Cancer

Author

Geoffrey J. Lindeman, Jane E. Visvader, Daniel H.D. Gray, Sarah-Jane Dawson, Andjelija Zivanovic Bujak, Miriam M. Yeung, Belinda Yeo, Avraham Travers, Leanne Taylor, Gordon K. Smyth, Zhen R. Siow, Maria João Silva, Kylie Shackleton, Mark A. Rosenthal, Andrew W. Roberts, Bhupinder Pal, Anand Murugasu, Kate Moodie, G. Bruce Mann, He K. Liu, Danny Liew, Luke C. Gandolfo, Sarah Ftouni, Jayesh Desai, Alice R.T. Bergin, Antonia N. Policheni, Louisa L. Lo, Charis E. Teh, François Vaillant, James R. Whittle, and Sheau W. Lok

Abstract

Supplementary Methods

Published
2023
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3. Tables S1-5 from A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2–Positive Metastatic Breast Cancer

Author

Geoffrey J. Lindeman, Jane E. Visvader, Daniel H.D. Gray, Sarah-Jane Dawson, Andjelija Zivanovic Bujak, Miriam M. Yeung, Belinda Yeo, Avraham Travers, Leanne Taylor, Gordon K. Smyth, Zhen R. Siow, Maria João Silva, Kylie Shackleton, Mark A. Rosenthal, Andrew W. Roberts, Bhupinder Pal, Anand Murugasu, Kate Moodie, G. Bruce Mann, He K. Liu, Danny Liew, Luke C. Gandolfo, Sarah Ftouni, Jayesh Desai, Alice R.T. Bergin, Antonia N. Policheni, Louisa L. Lo, Charis E. Teh, François Vaillant, James R. Whittle, and Sheau W. Lok

Abstract

Supplementary Tables S1-5

Published
2023
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4. Table S8 from A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2–Positive Metastatic Breast Cancer

Author

Geoffrey J. Lindeman, Jane E. Visvader, Daniel H.D. Gray, Sarah-Jane Dawson, Andjelija Zivanovic Bujak, Miriam M. Yeung, Belinda Yeo, Avraham Travers, Leanne Taylor, Gordon K. Smyth, Zhen R. Siow, Maria João Silva, Kylie Shackleton, Mark A. Rosenthal, Andrew W. Roberts, Bhupinder Pal, Anand Murugasu, Kate Moodie, G. Bruce Mann, He K. Liu, Danny Liew, Luke C. Gandolfo, Sarah Ftouni, Jayesh Desai, Alice R.T. Bergin, Antonia N. Policheni, Louisa L. Lo, Charis E. Teh, François Vaillant, James R. Whittle, and Sheau W. Lok

Abstract

Supplementary Table S8

Published
2023
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5. Figures S1-8 from A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2–Positive Metastatic Breast Cancer

Author

Geoffrey J. Lindeman, Jane E. Visvader, Daniel H.D. Gray, Sarah-Jane Dawson, Andjelija Zivanovic Bujak, Miriam M. Yeung, Belinda Yeo, Avraham Travers, Leanne Taylor, Gordon K. Smyth, Zhen R. Siow, Maria João Silva, Kylie Shackleton, Mark A. Rosenthal, Andrew W. Roberts, Bhupinder Pal, Anand Murugasu, Kate Moodie, G. Bruce Mann, He K. Liu, Danny Liew, Luke C. Gandolfo, Sarah Ftouni, Jayesh Desai, Alice R.T. Bergin, Antonia N. Policheni, Louisa L. Lo, Charis E. Teh, François Vaillant, James R. Whittle, and Sheau W. Lok

Abstract

Supplementary Figures

Published
2023
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6. Ethnicity, Immunity, and Outcomes: Biology versus Socioeconomic Status

Author

Alice R.T. Bergin, Roberto Salgado, and Sherene Loi

Subjects
Cancer Research, Immunology
Abstract

Substantial advances in our understanding of breast cancer disease biology have led to marked improvements in cancer outcomes over the past two decades. These advances have largely focused on women from developed, high-income countries and as a result, significant disparities exist. In this issue, Bauer and colleagues provide new insight into the breast cancer immune microenvironment from women across geographic regions in sub-Saharan Africa, despite inherent infrastructure limitations. The study amassed data from 1,497 women from sub-Saharan Africa, and 117 women from Germany with breast cancer, suggesting regional variation in immune composition but with no significant prognostic impact. These important findings require validation in large, codesigned prospective studies to fully understand the impact of biology, ethnicity, and socioeconomic status on breast cancer outcomes. See related article by Bauer and colleagues (2) .

Published
2023
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