1. Extramedullary Hematopoiesis of the Conjunctiva Presenting as Active Systemic Disease in a Patient With Myelofibrosis
- Author
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Christopher Cendrowski, Nirupa Cuttler, David G. Heidemann, Robert Folberg, and Ali-Reza Armin
- Subjects
Male ,Systemic disease ,Pathology ,medicine.medical_specialty ,Conjunctiva ,Clinicopathological correlation ,Visual Acuity ,Conjunctival Diseases ,Immunoenzyme Techniques ,Lesion ,Antigens, CD ,Nitriles ,medicine ,Humans ,Myelofibrosis ,Aged ,Janus Kinases ,Peroxidase ,Factor VIII ,business.industry ,Fornix ,medicine.disease ,Combined Modality Therapy ,Extramedullary hematopoiesis ,Ophthalmology ,Pyrimidines ,medicine.anatomical_structure ,Primary Myelofibrosis ,Hematopoiesis, Extramedullary ,Pyrazoles ,Radiotherapy, Adjuvant ,sense organs ,medicine.symptom ,business ,Biomarkers - Abstract
PURPOSE To report the clinicopathological correlation of extramedullary hematopoiesis (EMH) of the conjunctiva in a patient with a history of myelofibrosis. METHODS Case report. RESULTS Elevated pink conjunctival lesions developed bilaterally in a 73-year-old man who had been treated for myelofibrosis for 13 years. EMH was detected in the examination of tissue from the lesion of the inferior fornix of the right eye. CONCLUSIONS The appearance of conjunctival lesions in a patient with myelofibrosis may indicate underlying pathology of EMH that may necessitate a change in systemic treatment of this condition.
- Published
- 2014