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Renal failure is a frequent complication of multiple myeloma (MM). Recently, the combination of lenalidomide-dexamethasone has become one of the cornerstone regimens for the treatment of MM. Impairment of renal function exacerbation is a rare, but potential, complication of lenalidomide therapy in plasma cell dyscrasias. We present two patients who developed exacerbation of renal function during their first cycle of therapy with lenalidomide. In the first case, we present a 76-year-old-male with MM and impaired renal function, who declined two weeks after initiation of second-line therapy with lenalidomide. His renal functions improved after discontinuation of lenalidomide and with supportive care. In the second case, we describe a 61-year-old woman who was started on lenalidomide for relapsed MM and admitted to intensive care unit three weeks later due to severe renal failure. Despite intensive supportive care, her renal function deteriorated even more and she died. We conclude that renal failure is an uncommon, but serious, potential complication of lenalidomide therapy in plasma cell dyscrasias, particularly MM. Close monitoring of renal function is clearly recommended during this treatment.

This study aims to investigate the relationship between oil host community and TOTAL Company that operates in block 10 in Sah district in Hadramout governorate, Yemen. Moreover, the study examined the relationship between the philanthropic activities provided by the company and the environmental impact caused by oil operation of the company, and the satisfaction of host communities. The quantitative research method was used by distributing 270 questionnaires in host communities in Saha district, Hadramout governorate. Furthermore, this research used simple random sample to collect the data and SPSS was used for descriptive analysis and cleaning the data while Partial Least Squares Structural Equation Modeling (PLS-SEM) used to testing the hypothesis.The results found that the level of host community's satisfaction is low. In addition, it approved that there is a positive relationship between philanthropic activities and the host community's satisfaction. Furthermore, the study revealed there is a negative relationship between the environmental impact caused by the company' operations and the host community's satisfaction. The study recommended that to promote the host community's satisfaction the oil producing company need to concentrate on protecting the environment form oil accidents and offering the charity activities for the resident of host community.

Aortitis, which is well described in patients with other spondyloarthritides, has been rarely cited in relation to psoriatic arthropathy (PsA). Two patients with known PsA, who developed aortitis, are reported herein. The PubMed database was searched using the following keywords: aortitis, Takaysu arteritis, PsA, ankylosing spondylitis, reactive arthritis, inflammatory bowel disease. The relevant articles were critically reviewed and pertinent data organized. Analysis of 5 cases of aortitis in patients with PsA, including the 2 cases reported herein, revealed no specific pattern of PsA joint involvement in the patients who developed aortitis. All aortic segments can be involved and complications, such as insufficiency of the aortic valve and stenosis of the major aortic branches, have been described. The genetic association involving the IL12B locus may be involved in the clinical association of aortitis and spondyloarthritis.