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15 results on '"Alhakeem, Raafat F"'

1. Middle East Respiratory Syndrome Coronavirus Infection Dynamics and Antibody Responses among Clinically Diverse Patients, Saudi Arabia

Author

Abdely, Hail M. Al-, Midgley, Claire M., Alkhamis, Abdulrahim M., Abedi, Glen R., Lu, Xiaoyan, Binder, Alison M., Alanazi, Khalid H., Tamin, Azaibi, Banjar, Weam M., Lester, Sandra, Abdalla, Osman, Dahl, Rebecca M., Mohammed, Mutaz, Trivedi, Suvang, Algarni, Homoud S., Sakthivel, Senthilkumar K., Algwizani, Abdullah, Bafaqeeh, Fahad, Alzahrani, Abdullah, Alsharef, Ali Abraheem, Alhakeem, Raafat F., Jokhdar, Hani A. Aziz, Ghazal, Sameeh S., Thornburg, Natalie J., Erdman, Dean D., Assiri, Abdullah M., Watson, John T., and Gerber, Susan I.

Subjects
United States. Centers for Disease Control and Prevention, Mortality -- Middle East -- Saudi Arabia, Middle East respiratory syndrome -- Development and progression -- Health aspects, Medical research -- Health aspects, Antibodies -- Health aspects, RNA -- Health aspects, Therapeutics, Polymerase chain reaction, Health
Abstract

Infection with Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) results in a wide range of clinical manifestations, from mild or asymptomatic illness to severe respiratory failure (1-8); infection has a [...]

Published
2019
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2. Epidemiology of a Novel Recombinant Middle East Respiratory Syndrome Coronavirus in Humans in Saudi Arabia

Author

Assiri, Abdullah M., Midgley, Claire M., Abedi, Glen R., Saeed, Abdulaziz Bin, Almasri, Malak M., Lu, Xiaoyan, Al-Abdely, Hail M., Abdalla, Osman, Mohammed, Mutaz, Algarni, Homoud S., Alhakeem, Raafat F., Sakthivel, Senthilkumar K., Nooh, Randa, Alshayab, Zainab, Alessa, Mohammad, Srinivasamoorthy, Ganesh, AlQahtani, Saeed Yahya, Kheyami, Ali, HajOmar, Waleed Husein, Banaser, Talib M., Esmaeel, Ahmad, Hall, Aron J., Curns, Aaron T., Tamin, Azaibi, Alsharef, Ali Abraheem, Erdman, Dean, Watson, John T., and Gerber, Susan I.

Published
2016

3. Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study

Author

Müller, Marcel A, Meyer, Benjamin, Corman, Victor M, Al-Masri, Malak, Turkestani, Abdulhafeez, Ritz, Daniel, Sieberg, Andrea, Aldabbagh, Souhaib, Bosch, Berend-J, Lattwein, Erik, Alhakeem, Raafat F, Assiri, Abdullah M, Albarrak, Ali M, Al-Shangiti, Ali M, Al-Tawfiq, Jaffar A, Wikramaratna, Paul, Alrabeeah, Abdullah A, Drosten, Christian, and Memish, Ziad A

Published
2015
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5. Exposures among MERS case-patients, Saudi Arabia, January-February 2016

Author

Alhakeem, Raafat F., Midgley, Claire M., Assiri, Abdullah M., Alessa, Mohammed, Hawaj, Hassan Al, Saeed, Abdulaziz Bin, Almasri, Malak M., Lu, Xiaoyan, Abedi, Glen R., Abdalla, Osman, Mohammed, Mutaz, Algarni, Homoud S., Al-Abdely, Hail M., Alsharef, Ali Abraheem, Nooh, Randa, Erdman, Dean D., Gerber, Susan I., and Watson, John T.

Subjects
Prevalence studies (Epidemiology), Middle East respiratory syndrome -- Distribution, Company distribution practices, Health
Abstract

To the Editor: Risk factors for primary acquisition of Middle East respiratory syndrome (MERS) coronavirus (CoV) include recent direct contact with dromedary camels (1), but secondary transmission, associated with healthcare [...]

Published
2016

6. Transmission of MERS-Coronavirus in Household Contacts

Author

Drosten, Christian, Meyer, Benjamin, Müller, Marcel A., Corman, Victor M., Al-Masri, Malak, Hossain, Raheela, Madani, Hosam, Sieberg, Andrea, Bosch, Berend Jan, Lattwein, Erik, Alhakeem, Raafat F., Assiri, Abdullah M., Hajomar, Waleed, Albarrak, Ali M., Al-Tawfiq, Jaffar A., Zumla, Alimuddin I., and Memish, Ziad A.

Published
2014
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7. Middle East Respiratory Syndrome Coronavirus Infection Dynamics and Antibody Responses among Clinically Diverse Patients, Saudi Arabia

Author

Al-Abdely, Hail M., primary, Midgley, Claire M., additional, Alkhamis, Abdulrahim M., additional, Abedi, Glen R., additional, Lu, Xiaoyan, additional, Binder, Alison M., additional, Alanazi, Khalid H., additional, Tamin, Azaibi, additional, Banjar, Weam M., additional, Lester, Sandra, additional, Abdalla, Osman, additional, Dahl, Rebecca M., additional, Mohammed, Mutaz, additional, Trivedi, Suvang, additional, Algarni, Homoud S., additional, Sakthivel, Senthilkumar K., additional, Algwizani, Abdullah, additional, Bafaqeeh, Fahad, additional, Alzahrani, Abdullah, additional, Alsharef, Ali Abraheem, additional, Alhakeem, Raafat F., additional, Jokhdar, Hani A. Aziz, additional, Ghazal, Sameeh S., additional, Thornburg, Natalie J., additional, Erdman, Dean D., additional, Assiri, Abdullah M., additional, Watson, John T., additional, and Gerber, Susan I., additional

Published
2019
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8. Scope and extent of healthcare-associated Middle East respiratory syndrome coronavirus transmission during two contemporaneous outbreaks in Riyadh, Saudi Arabia, 2017

Author

Alanazi, Khalid H., primary, Killerby, Marie E., additional, Biggs, Holly M., additional, Abedi, Glen R., additional, Jokhdar, Hani, additional, Alsharef, Ali A., additional, Mohammed, Mutaz, additional, Abdalla, Osman, additional, Almari, Aref, additional, Bereagesh, Samar, additional, Tawfik, Sameh, additional, Alresheedi, Husain, additional, Alhakeem, Raafat F., additional, Hakawi, Ahmed, additional, Alfalah, Haitham, additional, Amer, Hala, additional, Thornburg, Natalie J., additional, Tamin, Azaibi, additional, Trivedi, Suvang, additional, Tong, Suxiang, additional, Lu, Xiaoyan, additional, Queen, Krista, additional, Li, Yan, additional, Sakthivel, Senthilkumar K., additional, Tao, Ying, additional, Zhang, Jing, additional, Paden, Clinton R., additional, Al-Abdely, Hail M., additional, Assiri, Abdullah M., additional, Gerber, Susan I., additional, and Watson, John T., additional

Published
2018
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9. Infectious MERS-CoV Isolated From a Mildly Ill Patient, Saudi Arabia

Author

Al-Abdely, Hail M, primary, Midgley, Claire M, additional, Alkhamis, Abdulrahim M, additional, Abedi, Glen R, additional, Tamin, Azaibi, additional, Binder, Alison M, additional, Alanazi, Khalid, additional, Lu, Xiaoyan, additional, Abdalla, Osman, additional, Sakthivel, Senthilkumar K, additional, Mohammed, Mutaz, additional, Queen, Krista, additional, Algarni, Homoud S, additional, Li, Yan, additional, Trivedi, Suvang, additional, Algwizani, Abdullah, additional, Alhakeem, Raafat F, additional, Thornburg, Natalie J, additional, Tong, Suxiang, additional, Ghazal, Sameeh S, additional, Erdman, Dean D, additional, Assiri, Abdullah M, additional, Gerber, Susan I, additional, and Watson, John T, additional

Published
2018
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10. A country on the verge of malaria elimination--the Kingdom of Saudi Arabia

Author

Coleman, Michael, Al-Zahrani, Mohammed H., Coleman, Marlize, Hemingway, Janet, Omar, Abdiasiis, Stanton, Michelle, Thomsen, Edward, Alsheikh, Adel A., Alhakeem, Raafat F., McCall, Philip, Rabeeah, Abdullah A. Al, and Memish, Ziad A.

Subjects
parasitic diseases, lcsh:R, lcsh:Medicine, lcsh:Q, wc_765, lcsh:Science, wc_750
Abstract

Significant headway has been made in the global fight against malaria in the past decade and as more countries enter the elimination phase, attention is now focused on identifying effective strategies to shrink the malaria map. Saudi Arabia experienced an outbreak of malaria in 1998, but is now on the brink of malaria elimination, with just 82 autochthonous cases reported in 2012. A review of published and grey literature was performed to identify the control strategies that have contributed to this achievement. The number of autochthonous malaria cases in Saudi Arabia decreased by 99.8% between 1998 and 2012. The initial steep decline in malaria cases coincided with a rapid scaling up of vector control measures. Incidence continued to be reported at low levels (between 0.01 and 0.1 per 1,000 of the population) until the adoption of artesunate plus sulfadoxine-pyrimethamine as first line treatment and the establishment of a regional partnership for a malaria-free Arabian Peninsula, both of which occurred in 2007. Since 2007, incidence has decreased by nearly an order of magnitude. Malaria incidence is now very low, but a high proportion of imported cases, continued potential for autochthonous transmission, and an increased proportion of cases attributable to Plasmodium vivax all present challenges to Saudi Arabia as they work toward elimination by 2015.

Published
2014

11. Increase in Middle East Respiratory Syndrome-Coronavirus Cases in Saudi Arabia Linked to Hospital Outbreak With Continued Circulation of Recombinant Virus, July 1–August 31, 2015

Author

Assiri, Abdullah M., primary, Biggs, Holly M., additional, Abedi, Glen R., additional, Lu, Xiaoyan, additional, Bin Saeed, Abdulaziz, additional, Abdalla, Osman, additional, Mohammed, Mutaz, additional, Al-Abdely, Hail M., additional, Algarni, Homoud S., additional, Alhakeem, Raafat F., additional, Almasri, Malak M., additional, Alsharef, Ali A., additional, Nooh, Randa, additional, Erdman, Dean D., additional, Gerber, Susan I., additional, and Watson, John T., additional

Published
2016
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12. Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study

Author

LS Virologie, dI&I I&I-1, Müller, Marcel A, Meyer, Benjamin, Corman, Victor M, Al-Masri, Malak, Turkestani, Abdulhafeez, Ritz, Daniel, Sieberg, Andrea, Aldabbagh, Souhaib, Bosch, Berend-J, Lattwein, Erik, Alhakeem, Raafat F, Assiri, Abdullah M, Albarrak, Ali M, Al-Shangiti, Ali M, Al-Tawfiq, Jaffar A, Wikramaratna, Paul, Alrabeeah, Abdullah A, Drosten, Christian, Memish, Ziad A, LS Virologie, dI&I I&I-1, Müller, Marcel A, Meyer, Benjamin, Corman, Victor M, Al-Masri, Malak, Turkestani, Abdulhafeez, Ritz, Daniel, Sieberg, Andrea, Aldabbagh, Souhaib, Bosch, Berend-J, Lattwein, Erik, Alhakeem, Raafat F, Assiri, Abdullah M, Albarrak, Ali M, Al-Shangiti, Ali M, Al-Tawfiq, Jaffar A, Wikramaratna, Paul, Alrabeeah, Abdullah A, Drosten, Christian, and Memish, Ziad A

Published
2015

13. Progress toward malaria elimination in Jazan Province, Kingdom of Saudi Arabia: 2000–2014

Author

El Hassan, Ibrahim M., primary, Sahly, Ahmed, additional, Alzahrani, Mohammed H., additional, Alhakeem, Raafat F., additional, Alhelal, Mohammed, additional, Alhogail, Abdollah, additional, Alsheikh, Adil A. H., additional, Assiri, Abdullah M., additional, ElGamri, Tageddin B., additional, Faragalla, Ibrahim A., additional, Al-Atas, Mohammed, additional, Akeel, Mohammed A., additional, Bani, Ibrahim, additional, Ageely, Hussein M., additional, BinSaeed, Abdulaziz A., additional, Kyalo, David, additional, Noor, Abdisalan M., additional, and Snow, Robert W., additional

Published
2015
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14. Transmission of MERS-coronavirus in household contacts

Author

LS Virologie, Strategic Infection Biology, I&I SIB1, Drosten, Christian, Meyer, Benjamin, Müller, Marcel A, Corman, Victor M, Al-Masri, Malak, Hossain, Raheela, Madani, Hosam, Sieberg, Andrea, Bosch, Berend Jan, Lattwein, Erik, Alhakeem, Raafat F, Assiri, Abdullah M, Hajomar, Waleed, Albarrak, Ali M, Al-Tawfiq, Jaffar A, Zumla, Alimuddin I, Memish, Ziad A, LS Virologie, Strategic Infection Biology, I&I SIB1, Drosten, Christian, Meyer, Benjamin, Müller, Marcel A, Corman, Victor M, Al-Masri, Malak, Hossain, Raheela, Madani, Hosam, Sieberg, Andrea, Bosch, Berend Jan, Lattwein, Erik, Alhakeem, Raafat F, Assiri, Abdullah M, Hajomar, Waleed, Albarrak, Ali M, Al-Tawfiq, Jaffar A, Zumla, Alimuddin I, and Memish, Ziad A

Published
2014

15. Scope and extent of healthcare-associated Middle East respiratory syndrome coronavirus transmission during two contemporaneous outbreaks in Riyadh, Saudi Arabia, 2017

Author

Alanazi, Khalid H., Killerby, Marie E., Biggs, Holly M., Abedi, Glen R., Jokhdar, Hani, Alsharef, Ali A., Mohammed, Mutaz, Abdalla, Osman, Almari, Aref, Bereagesh, Samar, Tawfik, Sameh, Alresheedi, Husain, Alhakeem, Raafat F., Hakawi, Ahmed, Alfalah, Haitham, Amer, Hala, Thornburg, Natalie J., Tamin, Azaibi, Trivedi, Suvang, Tong, Suxiang, Lu, Xiaoyan, Queen, Krista, Li, Yan, Sakthivel, Senthilkumar K., Tao, Ying, Zhang, Jing, Paden, Clinton R., Al-Abdely, Hail M., Assiri, Abdullah M., Gerber, Susan I., and Watson, John T.

Abstract

AbstractObjectiveTo investigate a Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak event involving multiple healthcare facilities in Riyadh, Saudi Arabia; to characterize transmission; and to explore infection control implications.DesignOutbreak investigation.SettingCases presented in 4 healthcare facilities in Riyadh, Saudi Arabia: a tertiary-care hospital, a specialty pulmonary hospital, an outpatient clinic, and an outpatient dialysis unit.MethodsContact tracing and testing were performed following reports of cases at 2 hospitals. Laboratory results were confirmed by real-time reverse transcription polymerase chain reaction (rRT-PCR) and/or genome sequencing. We assessed exposures and determined seropositivity among available healthcare personnel (HCP) cases and HCP contacts of cases.ResultsIn total, 48 cases were identified, involving patients, HCP, and family members across 2 hospitals, an outpatient clinic, and a dialysis clinic. At each hospital, transmission was linked to a unique index case. Moreover, 4 cases were associated with superspreading events (any interaction where a case patient transmitted to ≥5 subsequent case patients). All 4 of these patients were severely ill, were initially not recognized as MERS-CoV cases, and subsequently died. Genomic sequences clustered separately, suggesting 2 distinct outbreaks. Overall, 4 (24%) of 17 HCP cases and 3 (3%) of 114 HCP contacts of cases were seropositive.ConclusionsWe describe 2 distinct healthcare-associated outbreaks, each initiated by a unique index case and characterized by multiple superspreading events. Delays in recognition and in subsequent implementation of control measures contributed to secondary transmission. Prompt contact tracing, repeated testing, HCP furloughing, and implementation of recommended transmission-based precautions for suspected cases ultimately halted transmission.

Published
2019
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