381 results on '"Alexopoulos, Leonidas G"'
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2. Comparative toxicological assessment of cigarettes and new category products via an in vitro multiplex proteomics platform
3. Protein kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
4. A network-based computational and experimental framework for repurposing compounds toward the treatment of non-alcoholic fatty liver disease
5. Regulatory network-based model to simulate the biochemical regulation of chondrocytes in healthy and osteoarthritic environments
6. Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting
7. Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis
8. MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis
9. A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation
10. Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis
11. Accurate SARS-CoV-2 seroprevalence surveys require robust multi-antigen assays
12. DPS-2: A Novel Dual MEK/ERK and PI3K/AKT Pathway Inhibitor with Powerful Ex Vivo and In Vivo Anticancer Properties
13. Multiscale networks in multiple sclerosis
14. Predicting disease severity in multiple sclerosis using multimodal data and machine learning
15. Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling
16. Selective cytotoxicity of the herbal substance acteoside against tumor cells and its mechanistic insights
17. Network-based technologies for early drug discovery
18. TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma
19. Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma
20. Mechanism-based biomarker discovery
21. Α Humanized RANKL Transgenic Mouse Model of Progestin-Induced Mammary Carcinogenesis for Evaluation of Novel Therapeutics
22. A Combination of Conformation-Specific RAF Inhibitors Overcome Drug Resistance Brought about by RAF Overexpression
23. A Computational Platform and Guide for Acceleration of Novel Medicines and Personalized Medicine
24. Solid stress-induced migration is mediated by GDF15 through Akt pathway activation in pancreatic cancer cells
25. Multi-tissue network analysis for drug prioritization in knee osteoarthritis
26. Ras suppressor-1 (RSU-1) promotes cell invasion in aggressive glioma cells and inhibits it in non-aggressive cells through STAT6 phospho-regulation
27. Targeted Proteomic Analysis of Patients with Ascending Thoracic Aortic Aneurysm
28. Data from Comparing Signaling Networks between Normal and Transformed Hepatocytes Using Discrete Logical Models
29. Supplementary Methods, Figures 1-8 from Comparing Signaling Networks between Normal and Transformed Hepatocytes Using Discrete Logical Models
30. Cue-Signal-Response Analysis in 3D Chondrocyte Scaffolds with Anabolic Stimuli
31. Predicting single cell genotypes from single cell expression profiles in AML using deep learning
32. Protein Kinase D Drives the Secretion of Invasion Mediators in Triple-Negative Breast Cancer Cell Lines
33. Phosphoproteomics in drug discovery
34. Post-treatment de-phosphorylation of p53 correlates with dasatinib responsiveness in malignant melanoma
35. Correction to: Cue-Signal-Response Analysis in 3D Chondrocyte Scaffolds with Anabolic Stimuli
36. Lysophosphatidic Acid Is a Proinflammatory Stimulus of Renal Tubular Epithelial Cells
37. Immuno-Modulatory Effects of Intervertebral Disc Cells
38. Networks Inferred from Biochemical Data Reveal Profound Differences in Toll-like Receptor and Inflammatory Signaling between Normal and Transformed Hepatocytes
39. Epicardial Adipocyte-derived TNF-α Modulates Local Inflammation in Patients with Advanced Coronary Artery Disease
40. Synergistic drug–cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity
41. DeepSNEM: Deep Signaling Network Embeddings for compound mechanism of action identification
42. Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis
43. A crowd-sourcing approach for the construction of species-specific cell signaling networks
44. Mechanical Compression Regulates Brain Cancer Cell Migration Through MEK1/Erk1 Pathway Activation and GDF15 Expression
45. Additional file 2 of Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis
46. Additional file 3 of Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis
47. Additional file 1 of Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis
48. Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting
49. Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis
50. Zonal Uniformity in Mechanical Properties of the Chondrocyte Pericellular Matrix: Micropipette Aspiration of Canine Chondrons Isolated by Cartilage Homogenization
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