Search

Your search keyword '"Alexie Mukeshimana"' showing total 6 results
Start Over Author "Alexie Mukeshimana"
6 results on '"Alexie Mukeshimana"'

1. Effects of a liquefied petroleum gas stove and fuel intervention on head circumference and length at birth: A multi-country household air pollution intervention network (HAPIN) trial

Author

Hina Raheel, Sheela Sinharoy, Anaité Diaz-Artiga, Sarada S. Garg, Ajay Pillarisetti, Kalpana Balakrishnan, Marilu Chiang, Amy Lovvorn, Miles Kirby, Usha Ramakrishnan, Shirin Jabbarzadeh, Alexie Mukeshimana, Michael Johnson, John P. McCracken, Luke P. Naeher, Ghislaine Rosa, Jiantong Wang, Joshua Rosenthal, William Checkley, Thomas F. Clasen, Jennifer L. Peel, and Lisa M. Thompson

Subjects
Birth length, Head circumference, Household air pollution, LPG stove, Intervention, Environmental sciences, GE1-350
Abstract

Background: Air pollution may impair child growth and cognitive development, with potential markers including birth length and head circumference. Methods: The Household Air Pollution Intervention Network (HAPIN) trial was an open label multi-country-randomized controlled trial, with 3200 pregnant women aged 18–34 years (9–19 weeks of gestation) randomly assigned in a 1:1 ratio to receive liquefied petroleum gas (LPG) stove intervention compared to women continuing to cook with solid fuels for 18 months. Particulate matter ≤ 2.5 μm (PM2.5), black carbon (BC) and carbon monoxide (CO) 24-hour personal exposures were measured three times during pregnancy. Head circumference and length were measured

Published
2025
Full Text
View/download PDF

2. Effects of a LPG stove and fuel intervention on adverse maternal outcomes: A multi-country randomized controlled trial conducted by the Household Air Pollution Intervention Network (HAPIN)

Author

Ashley Younger, Abbey Alkon, Kristen Harknett, Miles A. Kirby, Lisa Elon, Amy E. Lovvorn, Jiantong Wang, Wenlu Ye, Anaité Diaz-Artiga, John P. McCracken, Adly Castañaza Gonzalez, Libny Monroy Alarcon, Alexie Mukeshimana, Ghislaine Rosa, Marilu Chiang, Kalpana Balakrishnan, Sarada S. Garg, Ajay Pillarisetti, Ricardo Piedrahita, Michael Johnson, Rachel Craik, Aris T. Papageorghiou, Ashley Toenjes, Ashlinn Quinn, Kendra N. Williams, Lindsay Underhill, Howard H. Chang, Luke P. Naeher, Joshua Rosenthal, William Checkley, Jennifer L. Peel, Thomas F. Clasen, and Lisa M. Thompson

Subjects
Cooking fuel, Birth outcomes, Household air pollution, Low- and middle-income countries, Spontaneous abortion, Hypertensive disorders of pregnancy, Environmental sciences, GE1-350
Abstract

Household air pollution from solid cooking fuel use during gestation has been associated with adverse pregnancy and birth outcomes. The Household Air Pollution Intervention Network (HAPIN) trial was a randomized controlled trial of free liquefied petroleum gas (LPG) stoves and fuel in Guatemala, Peru, India, and Rwanda. A primary outcome of the main trial was to report the effects of the intervention on infant birth weight. Here we evaluate the effects of a LPG stove and fuel intervention during pregnancy on spontaneous abortion, postpartum hemorrhage, hypertensive disorders of pregnancy, and maternal mortality compared to women who continued to use solid cooking fuels. Pregnant women (18–34 years of age; gestation confirmed by ultrasound at 9–19 weeks) were randomly assigned to an intervention (n = 1593) or control (n = 1607) arm. Intention-to-treat analyses compared outcomes between the two arms using log-binomial models. Among the 3195 pregnant women in the study, there were 10 spontaneous abortions (7 intervention, 3 control), 93 hypertensive disorders of pregnancy (47 intervention, 46 control), 11 post postpartum hemorrhage (5 intervention, 6 control) and 4 maternal deaths (3 intervention, 1 control). Compared to the control arm, the relative risk of spontaneous abortion among women randomized to the intervention was 2.32 (95% confidence interval (CI): 0.60, 8.96), hypertensive disorders of pregnancy 1.02 (95% CI: 0.68, 1.52), postpartum hemorrhage 0.83 (95% CI: 0.25, 2.71) and 2.98 (95% CI: 0.31, 28.66) for maternal mortality. In this study, we found that adverse maternal outcomes did not differ based on randomized stove type across four country research sites.

Published
2023
Full Text
View/download PDF

3. Lung Ultrasound Protocol and Quality Control of Image Interpretation Using an Adjudication Panel in the Household Air Pollution Intervention Network (HAPIN) Trial

Author

Suzanne M. Simkovich, Shakir Hossen, Eric D. McCollum, Ashley K. Toenjes, John P. McCracken, Lisa M. Thompson, Adly Castañaza, Anaite Diaz, Ghislaine Rosa, Miles A. Kirby, Alexie Mukeshimana, Rachel Myers, Patricia M. Lenzen, Rachel Craik, Shirin Jabbarzadeh, Lisa Elon, Sarada S. Garg, Kalpana Balakrishnan, Gurusamy Thangavel, Jennifer L. Peel, Thomas F. Clasen, Victor G. Dávila-Román, Aris T. Papageorghiou, Lisa de las Fuentes, and William Checkley

Subjects
Acoustics and Ultrasonics, Radiological and Ultrasound Technology, Biophysics, Radiology, Nuclear Medicine and imaging
Published
2023
Full Text
View/download PDF

4. Effects of a liquefied petroleum gas cookstove and fuel intervention on fetal and neonatal outcomes: a multi-country randomized controlled trial conducted by the Household Air Pollution Intervention Network (HAPIN) trial

Author

Ashley Younger, Abbey Alkon, Kristen Harknett, Miles A Kirby, Amy E. Lovvorn, Jiantong Wang, Anaité Diaz-Artiga, John P. McCracken, Ghislaine Rosa, Kalpana Balakrishnan, Adly Castañaza-Gonzalez, Libny Monroy-Alarcon, Alexie Mukeshimana, Sarada S. Garg, Lindsay Underhill, Howard H. Chang, Joshua Rosenthal, Aris Papageorghiou, William Checkley, Jennifer L. Peel, Thomas F. Clasen, and Lisa Thompson

Subjects
General Earth and Planetary Sciences, General Environmental Science
Published
2022
Full Text
View/download PDF

5. Effects of a liquefied petroleum gas cookstove and fuel intervention on preterm birth and gestational duration: the multi-country Household Air Pollution Intervention Network (HAPIN) trial

Author

Miles A. Kirby, Lisa Thompson, Ashley Toenjes, Aris Papageorghiou, Rachel Craik, Lisa Elon, Ashley Younger, Penelope P. Howards, Usha Ramakrishnan, John P. McCracken, Anaite Diaz-Artiga, Adly Castañaza-Gonzalez, Libny Monroy-Alarcon, Ghislaine Rose, Alexie Mukeshimana, Kalpana Balakrishnan, Sarada S. Garg, Lindsay J. Underhill, Michael Johnson, Ajay Pillarisetti, Ricardo Piedrahita, Joshua Rosenthal, Ashlinn Quinn, Lance Waller, Shirin Jabbarzadeh, Jiantong Wang, Kyle Steenland, Luke P. Naeher, Howard Chang, William Checkley, Thomas F. Clasen, and Jennifer L. Peel

Subjects
General Earth and Planetary Sciences, General Environmental Science
Published
2022
Full Text
View/download PDF

6. LPG stove and fuel intervention among pregnant women reduce fine particle air pollution exposures in three countries: Pilot results from the HAPIN trial

Author

Usha Ramakrishnan, Shirin Jabbarzadeh, Pattie Lenzen, Erick Mollinedo, Rachel Meyers, Penelope P. Howards, Anaite Diaz-Artiga, Ajay Pillarisetti, Kyle Steenland, Krishnendu Mukhopadhyay, Jiawen Liao, Kalpana Balakrishnan, Eduardo Canuz, Jean de Dieu Ntivuguruzwa, Fiona Majorin, Sheela S. Sinharoy, Ashlinn Quinn, Thomas Clasen, Miles A. Kirby, Eric D. McCollum, Jane Mbabazi, Ghislaine Rosa, Marilu Chiang, Bonnie N. Young, John P. McCracken, Viviane Valdes, Bernard Mutariyani, Florien Ndagijimana, Amy Lovvorn, Alejandra Bussalleu, Gloriose Bankundiye, Maggie L. Clark, Luke P. Naeher, Dana B. Barr, Suzanne M. Simkovich, Elisa Puzzolo, Steven A. Harvey, Gurusamy Thangavel, Naveen Puttaswamy, Jeremy A. Sarnat, Kendra N. Williams, Lisa M. Thompson, Wenlu Ye, Damien Swearing, Kirk R. Smith, Sankar Sambandam, Sarada S. Garg, Katherine A. Kearns, Lawrence H. Moulton, Rengaraj Ramasami, Yunyun Chen, Vigneswari Aravindalochanan, Marvin Johnson, Lisa de las Fuentes, Alexander Ramirez, Ian Hennessee, William Checkley, Ashley Toenjes, Shakir Hossen, Ricardo Piedrahita, P. Barry Ryan, Karthikeyan Rajamani, Joshua P. Rosenthal, Lisa Elon, Lindsay M. Jaacks, Ephrem Dusabimana, Jennifer L. Peel, Durairaj Natesan, Mayari Hengstermann, Lance A. Waller, Rachel Craik, Oscar de Leon, Victor G. Davila-Roman, Azhar Nizam, Aris T. Papageorghiou, Alexie Mukeshimana, Juan Gabriel Espinoza, Sudhakar Saidam, Adly Castañaza, Sarah Hamid, Phabiola Herrera, and Stella Hartinger

Subjects
Rural Population, Fine particulate, Health, Toxicology and Mutagenesis, Psychological intervention, Air pollution, Intervention, PM2.5, Health benefits, Toxicology, medicine.disease_cause, complex mixtures, Article, Interquartile range, Pregnancy, Environmental health, Intervention (counseling), Air Pollution, medicine, Humans, Cooking, Child, Air Pollutants, Clean cooking fuel, business.industry, Child Health, General Medicine, Pollution, Confidence interval, Personal exposure, Household air pollution, Petroleum, Stove, Air Pollution, Indoor, Women's Health, Cookstove, Female, Particulate Matter, Pregnant Women, business
Abstract

The Household Air Pollution Intervention Network trial is a multi-country study on the effects of a liquefied petroleum gas (LPG) stove and fuel distribution intervention on women's and children's health. There is limited data on exposure reductions achieved by switching from solid to clean cooking fuels in rural settings across multiple countries. As formative research in 2017, we recruited pregnant women and characterized the impact of the intervention on personal exposures and kitchen levels of fine particulate matter (PM2.5) in Guatemala, India, and Rwanda. Forty pregnant women were enrolled in each site. We measured cooking area concentrations of and personal exposures to PM2.5 for 24 or 48 h using gravimetric-based PM2.5 samplers at baseline and two follow-ups over two months after delivery of an LPG cookstove and free fuel supply. Mixed models were used to estimate PM2.5 reductions. Median kitchen PM2.5 concentrations were 296 μg/m3 at baseline (interquartile range, IQR: 158–507), 24 μg/m3 at first follow-up (IQR: 18–37), and 23 μg/m3 at second follow-up (IQR: 14–37). Median personal exposures to PM2.5 were 134 μg/m3 at baseline (IQR: 71–224), 35 μg/m3 at first follow-up (IQR: 23–51), and 32 μg/m3 at second follow-up (IQR: 23–47). Overall, the LPG intervention was associated with a 92% (95% confidence interval (CI): 90–94%) reduction in kitchen PM2.5 concentrations and a 74% (95% CI: 70–79%) reduction in personal PM2.5 exposures. Results were similar for each site. Conclusions The intervention was associated with substantial reductions in kitchen and personal PM2.5 overall and in all sites. Results suggest LPG interventions in these rural settings may lower exposures to the WHO annual interim target-1 of 35 μg/m3. The range of exposure contrasts falls on steep sections of estimated exposure-response curves for birthweight, blood pressure, and acute lower respiratory infections, implying potentially important health benefits when transitioning from solid fuels to LPG., Highlights • There was high uptake of an LPG stove and fuel intervention in 3 rural settings. • The LPG intervention was associated with a 92% reduction in kitchen PM2.5 levels. • The intervention was associated with a 74% reduction in personal exposure to PM2.5 • Maternal PM2.5 exposure was reduced to the WHO annual interim target-1 of 35 μg/m3. • Results from 3 countries indicate switching to clean fuel could improve health., Capsule summary: LPG stove and fuel intervention can reduce kitchen area and personal PM2.5 exposure levels in a pilot study of clean cookstove intervention trial. This strongly suggests switching to clean cook can improve health.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results