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This study was purposely made to assess biosecurity, or the management of risks to health, economy, industry, and environment. The consequences are caused by the worldwide pandemic proved the need for a biosecurity program, therefore making this study significant. The study utilized the qualitative research design, where ten participants from different professions and runs of life were surveyed and interviewed. Various online platforms like Messenger and Google forms, as well as a one-on-one individual depth interview, were conducted and used to gather the information needed. The findings are presented as follows: in terms of awareness, a community needs to be educated and knowledgeable about biosecurity; in terms of leadership and practice and implementation, to have success in biosecurity in the municipality, there must be a reliable leadership and strict implementation of ordinances; and in terms of behavior, it has a big role on strengthening biosecurity in Kalamansig. This study concluded that a biosecurity program is essential, and needs more attention in the Philippines. This study is beneficial to society in the present age and in the years to come as it aims to strengthen society’s human biosecurity and protect the health and well-being of every individual.

Neuropathic pain is a chronic disability associated with a dysfunction of the nervous system, initiated by a primary lesion or disease. Even after resolution of the initiating pathology, neuropathic pain often persists, leading to a significantly diminished quality of life. A vast literature has documented alterations in the expression and distribution of various pain-related proteins in the peripheral nervous system following injury or disease. The current review examines pain-related molecules in the pathogenesis of peripheral nerve injury-induced pain and discusses potentially useful therapeutic targets on the basis of preclinical findings in rodent neuropathic pain models. There are indeed a number of cellular processes that are involved in maintaining the neuropathic pain state, but the current review will focus on transmembrane proteins, particularly the voltage-gated and ligand-gated ion channels, which modulate peripheral nerve function. Given the complexity of the process involved in peripheral nerves, clinical efficacy could be greatly enhanced if several of these targets are engaged at once. A key advantage of therapy directed peripherally is that penetration of the therapeutic into the CNS is not entirely necessary, thereby reducing the risk of adverse psychomotor effects. While a number of fascinating targets have been identified in preclinical rodent models, there is a need to confirm that they are in fact relevant to clinical neuropathic pain. Thus, the current review will also discuss the extent to which clinical data confirms the findings of preclinical studies.