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385 results on '"Aldehyde Dehydrogenase chemistry"'

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1. Computational investigations of flavonoids as ALDH isoform inhibitors for treatment of cancer.

2. Molecular mechanics studies of factors affecting overall rate in cascade reactions: Multi-enzyme colocalization and environment.

3. Detection of aldehydes from degradation of lipid nanoparticle formulations using a hierarchically-organized nanopore electrochemical biosensor.

4. Discovery of Aldehyde Dehydrogenase as a Potential Fungicide Target and Screening of its Natural Inhibitors against Fusarium verticillioides .

5. Structural elucidation, binding sites exploration and biological activities of bound phenolics from Radix Puerariae Thomsonii.

6. N-carboxyacyl and N-α-aminoacyl derivatives of aminoaldehydes as shared substrates of plant aldehyde dehydrogenases 10 and 7.

7. FilamentID reveals the composition and function of metabolic enzyme polymers during gametogenesis.

8. Contribution of a C-Terminal Extension to the Substrate Affinity and Oligomeric Stability of Aldehyde Dehydrogenase from Thermus thermophilus HB27.

9. Biochemical, structural, and computational analyses of two new clinically identified missense mutations of ALDH7A1.

10. A comparative study of two aldehyde dehydrogenases from Sphingobium sp.: the substrate spectrum and catalytic mechanism.

11. Crystal structure of aldehyde dehydrogenase 1A1 from mouse.

12. Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1.

13. Curcumin-based-fluorescent probes targeting ALDH1A3 as a promising tool for glioblastoma precision surgery and early diagnosis.

14. Evolution of aldehyde dehydrogenase genes and proteins in diploid and allotetraploid Xenopus frog species.

15. Overexpression of the Aldehyde Dehydrogenase Gene ZmALDH Confers Aluminum Tolerance in Arabidopsis thaliana .

16. Study of ALDH from Thermus thermophilus -Expression, Purification and Characterisation of the Non-Substrate Specific, Thermophilic Enzyme Displaying Both Dehydrogenase and Esterase Activity.

17. Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans.

18. Impact of missense mutations in the ALDH7A1 gene on enzyme structure and catalytic function.

19. Mining of two novel aldehyde dehydrogenases (DHY-SC-VUT5 and DHY-G-VUT7) from metagenome of hydrocarbon contaminated soils.

20. Purification and characterization of molybdenum-containing aldehyde dehydrogenase that oxidizes benzyl maltol derivative from Pseudomonas nitroreducens SB32154.

21. The plant pathogen enzyme AldC is a long-chain aliphatic aldehyde dehydrogenase.

22. Inhibition, crystal structures, and in-solution oligomeric structure of aldehyde dehydrogenase 9A1.

23. Structural analysis of pathogenic mutations targeting Glu427 of ALDH7A1, the hot spot residue of pyridoxine-dependent epilepsy.

24. Coupled regulations of enzymatic activity and structure formation of aldehyde dehydrogenase Ald4p.

25. Molecular Dynamics Analysis of a Rationally Designed Aldehyde Dehydrogenase Gives Insights into Improved Activity for the Non-Native Cofactor NAD .

26. Functional models of nonheme diiron enzymes: reactivity of the μ-oxo-μ-1,2-peroxo-diiron(iii) intermediate in electrophilic and nucleophilic reactions.

27. Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.

28. Expression, purification and crystallization of the novel Xenopus tropicalis ALDH16B1, a homologue of human ALDH16A1.

29. Kinetic and structural analysis of human ALDH9A1.

30. Structural and Biochemical Characterization of Aldehyde Dehydrogenase 12, the Last Enzyme of Proline Catabolism in Plants.

31. Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer.

32. Engineering Clostridial Aldehyde/Alcohol Dehydrogenase for Selective Butanol Production.

33. Enhancement in the Catalytic Activity of Human Salivary Aldehyde Dehydrogenase by Alliin from Garlic: Implications in Aldehyde Toxicity and Oral Health.

34. NAD + promotes assembly of the active tetramer of aldehyde dehydrogenase 7A1.

35. The quaternary structure of Thermus thermophilus aldehyde dehydrogenase is stabilized by an evolutionary distinct C-terminal arm extension.

36. Chemoproteomics-Enabled Covalent Ligand Screening Reveals ALDH3A1 as a Lung Cancer Therapy Target.

37. Compound heterozygous mutations in two different domains of ALDH18A1 do not affect the amino acid levels in a patient with hereditary spastic paraplegia.

38. Experimental and computational modeling of interaction of kolaviron-kolaflavanone with aldehyde dehydrogenase.

39. Reassignment of the human aldehyde dehydrogenase ALDH8A1 (ALDH12) to the kynurenine pathway in tryptophan catabolism.

40. Expression and Interaction Analysis among Saffron ALDHs and Crocetin Dialdehyde.

41. The aldehyde dehydrogenase AldA contributes to the hypochlorite defense and is redox-controlled by protein S-bacillithiolation in Staphylococcus aureus.

42. Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles.

43. The In Situ Enzymatic Screening (ISES) Approach to Reaction Discovery and Catalyst Identification.

44. Crystal structures of an atypical aldehyde dehydrogenase having bidirectional oxidizing and reducing activities.

45. Importance of the C-Terminus of Aldehyde Dehydrogenase 7A1 for Oligomerization and Catalytic Activity.

46. ALDH7A1 is a protein that protects Atlantic salmon against Aeromonas salmonicida at the early stages of infection.

47. Thymoquinone binds and activates human salivary aldehyde dehydrogenase: Potential therapy for the mitigation of aldehyde toxicity and maintenance of oral health.

48. Modeling of interactions between functional domains of ALDH1L1.

49. Mechanisms of protection against irreversible oxidation of the catalytic cysteine of ALDH enzymes: Possible role of vicinal cysteines.

50. Spectroscopic evidences of toxic trans-crotonaldehyde trapped and transformed by resveratrol to prevent the damage of mitochondrial DNA.

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