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The objective of this study is to derive methane (CH4) emissions from three landfills, which are found to be the most significant CH4 sources in the metropolitan area of Madrid in Spain. We derive CH4 emissions from the CH4 enhancements observed by spaceborne and ground-based instruments. We apply satellite-based measurements from the TROPOspheric Monitoring Instrument (TROPOMI) and the Infrared Atmospheric Sounding Interferometer (IASI) together with measurements from the ground-based COllaborative Carbon Column Observing Network (COCCON) instruments. In 2018, a 2-week field campaign for measuring the atmospheric concentrations of greenhouse gases was performed in Madrid in the framework of Monitoring of the Greenhouse Gases Concentrations in Madrid (MEGEI-MAD) project. Five COCCON instruments were deployed at different locations around the Madrid city center, enabling the observation of total column-averaged CH4 mixing ratios (XCH4). Considering the prevalent wind regimes, we calculate the wind-assigned XCH4 anomalies for two opposite wind directions. Pronounced bipolar plumes are found when applying the method to NO2, which implies that our method of wind-assigned anomaly is suitable to estimate enhancements of trace gases at the urban level from satellite-based measurements. For quantifying the CH4 emissions, the wind-assigned plume method is applied to the TROPOMI XCH4 and to the lower tropospheric CH4 / dry-air column ratio (TXCH4) of the combined TROPOMI+IASI product. As CH4 emission strength we estimate 7.4 × 1025 ± 6.4 × 1024 molec. s−1 from the TROPOMI XCH4 data and 7.1 × 1025 ± 1.0 × 1025 molec. s−1 from the TROPOMI+IASI merged TXCH4 data. We use COCCON observations to estimate the local source strength as an independent method. COCCON observations indicate a weaker CH4 emission strength of 3.7 × 1025 molec. s−1 from a local source (the Valdemingómez waste plant) based on observations from a single day. This strength is lower than the one derived from the satellite observations, and it is a plausible result. This is because the analysis of the satellite data refers to a larger area, covering further emission sources in the study region, whereas the signal observed by COCCON is generated by a nearby local source. All emission rates estimated from the different observations are significantly larger than the emission rates provided via the official Spanish Register of Emissions and Pollutant Sources.

Bisphosphonate Related Osteonecrosis of the Jaw (BRONJ) is a pathology initially described in the early 2000s that has become increasingly common in clinical dentistry and maxillofacial practice due to the frequent use of bisphosphonates medical drugs (BPs) to treat various diseases such as osteoporosis, Paget's syndrome, osteomyelitis and in bone metastases secondary to tumors. Supragingival irrigation applied as monotherapy and in combination with root planning or BFs related bone necrosectomy revealed that supragingival irrigation with a variety of agents reduced the gingival microbial load and gingival inflammation. In this 4-year follow-up study we analyze the use of hydrogen peroxide (H2O2) as an antimicrobial agent for maintenance periodontal health, improving the longevity of teeth and oral cavity healing process.

The rehabilitation of maxillary bone atrophy represents one of the main challenges of modern oral implantology. The use of zygomatic implants in the prosthetic rehabilitation of the patient affected by severe maxillary bone atrophy is another therapeutic alternative, not exempt from complications. The present study included 19 patients with edentulous maxillae who were treated between 2013 to 2015 with at least two zygomatic implants at the Department of Maxillofacial Surgery, Verona, Italy. The purpose of this retrospective longitudinal study was to evaluate sinus complications and radiological, periodontal and prosthetic evaluations of zygomatic implants technique in severe atrophic. Implant-prosthetic rehabilitation of the upper jaw edentulous severely atrophic using zygomatic implants represents one safe and repeatable technique. In terms of implant survival from our study showed an implant CRS (common reporting standard) of 98.5% and a prosthetic CRS 100% with a mean follow-up period of 19.2 months (range). Both recorded data are superimposed on major reported studies in literature.

The introduction of computer-assisted and guided surgery has radically improved the possibility of using all available bone for implant support, reducing the need for extensive grafting procedures and allowing for better implant placement and restoration. Moreover, fresh frozen homologous bone (FFB) grafts have shown good osteoconductive properties and biocompatibility with results comparable to autologous bone patients. The purpose of this retrospective cohort study was to evaluate the survival and the success rate of implants and related fixed full arch prosthesis at the 5 to 8 years follow-up when performed with immediate function using a flapless surgical procedure and computer-aided technology (NobelGuide®, Nobel Biocare® AB, Goteborg, Sweden) in patients previously treated with FFB grafts; treated at the University of Verona with the NobelGuide® system from January 2007 to December 2012 with at least 5 years follow-up were reviewed. Survival implants and survival prosthesis' percentage reached 95% in a 5 to 8-year period. This study indicates that patients previously augmented with FFB graft for maxillary or mandibular bone atrophy can be safely treated with implant supported prosthesis based on the NobelGuide® protocol, with the aid of computer-generated guide.

Medication-related osteonecrosis of the jaw (MRONJ) is a major disease under study for over the last twenty years. Different classifications have been proposed and many therapies for the different stages have been applied. The evolution of treatments lead to an increasingly conservative approach. Numerous adjuvant treatments have been proposed in the last decade. All these complementary treatments have been proposed mainly to resolve or reduce the painful stress, predominantly caused by bacterial infection, simplifying the wound healing process and improving patients' compliance. Nowadays "secondary" treatments, such as autologous platelet concentrates (APCs, more specifically PRP, PRGF or PRF), hyperbaric oxygen (HBO), Auto/tetracycline fluorescence-guided bone surgery (AF-GBS/TF-GBS), medical drugs like teriparatide or the combination between pentoxifylline and tocopherol, fluorodeoxyglucose positron emission tomography (FDG-PET), laser and/or low-laser therapy and ozone therapy are more or less well documented and known considering their clinical effectiveness. The aim of the present review is the evaluation of the quantity and quality of scientific studies concerning this specific topic.