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6. Association of inflammation-related exposures and ovarian cancer survival in a multi-site cohort study of Black women

Author

Johnson, Courtney E., Alberg, Anthony J., Bandera, Elisa V., Peres, Lauren C., Akonde, Maxwell, Collin, Lindsay J., Cote, Michele L., Hastert, Theresa A., Hébert, James R., Peters, Edward S., Qin, Bonnie, Terry, Paul, Schwartz, Ann G., Bondy, Melissa, Epstein, Michael P., Mandle, Hannah B., Marks, Jeffrey R., Lawson, Andrew B., and Schildkraut, Joellen M.

Published
2023
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8. Identification of novel epithelial ovarian cancer loci in women of African ancestry

Author

Manichaikul, Ani, Peres, Lauren C, Wang, Xin‐Qun, Barnard, Mollie E, Chyn, Deanna, Sheng, Xin, Du, Zhaohui, Tyrer, Jonathan, Dennis, Joseph, Schwartz, Ann G, Cote, Michele L, Peters, Edward, Moorman, Patricia G, Bondy, Melissa, Barnholtz‐Sloan, Jill S, Terry, Paul, Alberg, Anthony J, Bandera, Elisa V, Funkhouser, Ellen, Wu, Anna H, Pearce, Celeste Leigh, Pike, Malcom, Setiawan, Veronica Wendy, Haiman, Christopher A, Consortium, the African American Breast Cancer, Consortium, the African Ancestry Prostate Cancer, Palmer, Julie R, LeMarchand, Loic, Wilkens, Lynne R, Berchuck, Andrew, Doherty, Jennifer A, Modugno, Francesmary, Ness, Roberta, Moysich, Kirsten, Karlan, Beth Y, Whittemore, Alice S, McGuire, Valerie, Sieh, Weiva, Lawrenson, Kate, Gayther, Simon, Sellers, Thomas A, Pharoah, Paul, Schildkraut, Joellen M, and Consortium, the African American Cancer Epidemiology Study and the Ovarian Cancer Association

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Health Disparities, Cancer, Minority Health, Clinical Research, Ovarian Cancer, Women's Health, Rare Diseases, Prevention, Genetics, Human Genome, Breast Cancer, 2.1 Biological and endogenous factors, Black or African American, Aldo-Keto Reductase Family 1 Member C3, Antigens, Neoplasm, Black People, Breast Neoplasms, Carcinoma, Ovarian Epithelial, Female, Follistatin, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Neoplasm Proteins, Polymorphism, Single Nucleotide, United States, White People, ovarian cancer, African ancestry, genome wide association study, gene expression, eQTLs, African American Breast Cancer Consortium, African Ancestry Prostate Cancer Consortium, African American Cancer Epidemiology Study (AACES) and the Ovarian Cancer Association Consortium, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

Women of African ancestry have lower incidence of epithelial ovarian cancer (EOC) yet worse survival compared to women of European ancestry. We conducted a genome-wide association study in African ancestry women with 755 EOC cases, including 537 high-grade serous ovarian carcinomas (HGSOC) and 1,235 controls. We identified four novel loci with suggestive evidence of association with EOC (p

Published
2020

9. Survival of epithelial ovarian cancer in Black women: a society to cell approach in the African American cancer epidemiology study (AACES)

Author

Schildkraut, Joellen M., Johnson, Courtney, Dempsey, Lauren F., Qin, Bo, Terry, Paul, Akonde, Maxwell, Peters, Edward S., Mandle, Hannah, Cote, Michele L., Peres, Lauren, Moorman, Patricia, Schwartz, Ann G., Epstein, Michael, Marks, Jeffrey, Bondy, Melissa, Lawson, Andrew B., Alberg, Anthony J., and Bandera, Elisa V.

Published
2023
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10. Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women

Author

Grant, Delores J, Manichaikul, Ani, Alberg, Anthony J, Bandera, Elisa V, Barnholtz‐Sloan, Jill, Bondy, Melissa, Cote, Michele L, Funkhouser, Ellen, Moorman, Patricia G, Peres, Lauren C, Peters, Edward S, Schwartz, Ann G, Terry, Paul D, Wang, Xin‐Qun, Keku, Temitope O, Hoyo, Cathrine, Berchuck, Andrew, Sandler, Dale P, Taylor, Jack A, O’Brien, Katie M, Edwards, Digna R Velez, Edwards, Todd L, Beeghly‐Fadiel, Alicia, Wentzensen, Nicolas, Pearce, Celeste Leigh, Wu, Anna H, Whittemore, Alice S, McGuire, Valerie, Sieh, Weiva, Rothstein, Joseph H, Modugno, Francesmary, Ness, Roberta, Moysich, Kirsten, Rossing, Mary Anne, Doherty, Jennifer A, Sellers, Thomas A, Permuth‐Way, Jennifer B, Monteiro, Alvaro N, Levine, Douglas A, Setiawan, Veronica Wendy, Haiman, Christopher A, LeMarchand, Loic, Wilkens, Lynne R, Karlan, Beth Y, Menon, Usha, Ramus, Susan, Gayther, Simon, Gentry‐Maharaj, Aleksandra, Terry, Kathryn L, Cramer, Daniel W, Goode, Ellen L, Larson, Melissa C, Kaufmann, Scott H, Cannioto, Rikki, Odunsi, Kunle, Etter, John L, Huang, Ruea‐Yea, Bernardini, Marcus Q, Tone, Alicia A, May, Taymaa, Goodman, Marc T, Thompson, Pamela J, Carney, Michael E, Tworoger, Shelley S, Poole, Elizabeth M, Lambrechts, Diether, Vergote, Ignace, Vanderstichele, Adriaan, Van Nieuwenhuysen, Els, Anton‐Culver, Hoda, Ziogas, Argyrios, Brenton, James D, Bjorge, Line, Salvensen, Helga B, Kiemeney, Lambertus A, Massuger, Leon FAG, Pejovic, Tanja, Bruegl, Amanda, Moffitt, Melissa, Cook, Linda, Le, Nhu D, Brooks‐Wilson, Angela, Kelemen, Linda E, Pharoah, Paul DP, Song, Honglin, Campbell, Ian, Eccles, Diana, DeFazio, Anna, Kennedy, Catherine J, and Schildkraut, Joellen M

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Prevention, Biotechnology, Ovarian Cancer, Women's Health, Genetics, Nutrition, Rare Diseases, Human Genome, Cancer, 2.1 Biological and endogenous factors, Black or African American, Bayes Theorem, Carcinoma, Ovarian Epithelial, ErbB Receptors, Female, Genetic Association Studies, Glucuronosyltransferase, Humans, Logistic Models, Middle Aged, Neoplasm Grading, Ovarian Neoplasms, Polymorphism, Single Nucleotide, Receptors, Calcitriol, Vitamin D, African ancestry risk, genetic association, ovarian cancer, vitamin D pathway, Biochemistry and Cell Biology, Oncology and carcinogenesis
Abstract

An association between genetic variants in the vitamin D receptor (VDR) gene and epithelial ovarian cancer (EOC) was previously reported in women of African ancestry (AA). We sought to examine associations between genetic variants in VDR and additional genes from vitamin D biosynthesis and pathway targets (EGFR, UGT1A, UGT2A1/2, UGT2B, CYP3A4/5, CYP2R1, CYP27B1, CYP24A1, CYP11A1, and GC). Genotyping was performed using the custom-designed 533,631 SNP Illumina OncoArray with imputation to the 1,000 Genomes Phase 3 v5 reference set in 755 EOC cases, including 537 high-grade serous (HGSOC), and 1,235 controls. All subjects are of African ancestry (AA). Logistic regression was performed to estimate odds ratios (OR) and 95% confidence intervals (CI). We further evaluated statistical significance of selected SNPs using the Bayesian False Discovery Probability (BFDP). A significant association with EOC was identified in the UGT2A1/2 region for the SNP rs10017134 (per allele OR = 1.4, 95% CI = 1.2-1.7, P = 1.2 × 10-6 , BFDP = 0.02); and an association with HGSOC was identified in the EGFR region for the SNP rs114972508 (per allele OR = 2.3, 95% CI = 1.6-3.4, P = 1.6 × 10-5 , BFDP = 0.29) and in the UGT2A1/2 region again for rs1017134 (per allele OR = 1.4, 95% CI = 1.2-1.7, P = 2.3 × 10-5 , BFDP = 0.23). Genetic variants in the EGFR and UGT2A1/2 may increase susceptibility of EOC in AA women. Future studies to validate these findings are warranted. Alterations in EGFR and UGT2A1/2 could perturb enzyme efficacy, proliferation in ovaries, impact and mark susceptibility to EOC.

Published
2019

11. Comorbid conditions and survival among Black women with ovarian cancer.

Author

Richards, Alicia R., Johnson, Courtney E., Montalvo, Nachalie Ramos, Alberg, Anthony J., Bandera, Elisa V., Bondy, Melissa, Collin, Lindsay J., Cote, Michele L., Hastert, Theresa A., Haller, Kristin, Khanna, Namita, Marks, Jeffrey R., Peters, Edward S., Qin, Bo, Staples, Jeanine, Terry, Paul D., Lawson, Andrew, Schildkraut, Joellen M., and Peres, Lauren C.

Subjects
TYPE 2 diabetes, OVARIAN epithelial cancer, PROPORTIONAL hazards models, PROGNOSIS, OVARIAN cancer
Abstract

Background: Black women with epithelial ovarian cancer (EOC) have worse survival and a higher burden of comorbid conditions compared with other racial groups. This study examines the association of comorbid conditions and medication use for these conditions with survival among Black women with EOC. Methods: In a prospective study of 592 Black women with EOC, the Charlson comorbidity index (CCI) based on self‐reported data, three cardiometabolic comorbidities (type 2 diabetes, hypertension, and hyperlipidemia), and medication use for each cardiometabolic comorbidity were evaluated. Cox proportional hazards regression models were used to examine the association of comorbid conditions and related medication use with all‐cause mortality while adjusting for relevant covariates overall and by histotype (high‐grade serous [HGS]/carcinosarcoma vs. non‐HGS/carcinosarcoma) and stage (I/II vs. III/IV). Results: A CCI of ≥2 was observed in 42% of the cohort, and 21%, 67%, and 34% of women had a history of type 2 diabetes, hypertension, and hyperlipidemia, respectively. After adjusting for prognostic factors, a CCI ≥2 (vs. 0; hazard ratio [HR], 1.33; 95% confidence interval [CI], 1.04–1.71) and type 2 diabetes (HR, 1.42; 95% CI, 1.10–1.84) were associated with an increased risk of mortality. The increased risk of mortality for type 2 diabetes was present specifically among women with HGS/carcinosarcoma (HR, 1.47; 95% CI, 1.10–1.97) and among women with stage III/IV disease (HR, 1.47; 95% CI, 1.10–1.98). The authors did not find evidence that hypertension, hyperlipidemia, or medication use for the cardiometabolic comorbidities meaningfully impacted survival. Conclusion: Comorbid conditions, especially type 2 diabetes, had a significant adverse impact on survival among Black women with EOC. In a population‐based study of Black women with ovarian cancer, a higher Charlson comorbidity index based on self‐reported data and type 2 diabetes were associated with an increased risk of mortality, but no association was observed for hypertension or hyperlipidemia. Medication use for comorbid conditions did not meaningfully impact survival in this patient population. [ABSTRACT FROM AUTHOR]

Published
2025
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12. Value of Peer Mentorship for Equity in Higher Education Leadership: A School of Public Health Focus with Implications for All Academic Administrators

Author

Friedman, Daniela B., Yelton, Brooks, Corwin, Sara J., Hardin, James W., Ingram, Lucy A., Torres-McGehee, Toni M., and Alberg, Anthony J.

Abstract

Diverse representation in higher education leadership is critical to the Academy's mission of teaching, research, and service. As academic leadership positions are rarely occupied by faculty from underrepresented gender and minoritized groups, inclusive mentorship practices are necessary to equip and support administrators of diverse backgrounds and identities. In this qualitative study, administrators from a school of public health in the southeastern United States present findings from an electronic survey exploring experiences with peer mentorship as it relates to leadership and training. Open-ended responses are compared with peer mentorship literature. Thematic analysis demonstrated peer mentorship is specifically beneficial for: (1) sharing knowledge and improving navigation; (2) cultivating change with respect and inclusivity; and (3) inspiring motivation and balance to prevent burnout. This study demonstrates the value of peer mentorship models for co-development of successful leadership qualities and for addressing administrative pressures through inclusive practices that promote diversity and improve equity.

Published
2021
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13. Racial/ethnic differences in the epidemiology of ovarian cancer: a pooled analysis of 12 case-control studies.

Author

Peres, Lauren C, Risch, Harvey, Terry, Kathryn L, Webb, Penelope M, Goodman, Marc T, Wu, Anna H, Alberg, Anthony J, Bandera, Elisa V, Barnholtz-Sloan, Jill, Bondy, Melissa L, Cote, Michele L, Funkhouser, Ellen, Moorman, Patricia G, Peters, Edward S, Schwartz, Ann G, Terry, Paul D, Manichaikul, Ani, Abbott, Sarah E, Camacho, Fabian, Jordan, Susan J, Nagle, Christina M, Australian Ovarian Cancer Study Group, Anne Rossing, Mary, Doherty, Jennifer A, Modugno, Francesmary, Moysich, Kirsten, Ness, Roberta, Berchuck, Andrew, Cook, Linda, Le, Nhu, Brooks-Wilson, Angela, Sieh, Weiva, Whittemore, Alice, McGuire, Valerie, Rothstein, Joseph, Anton-Culver, Hoda, Ziogas, Argyrios, Pearce, Celeste L, Tseng, Chiuchen, Pike, Malcom, Schildkraut, Joellen M, and African American Cancer Epidemiology Study and the Ovarian Cancer Association Consortium

Subjects
Australian Ovarian Cancer Study Group, African American Cancer Epidemiology Study and the Ovarian Cancer Association Consortium, Statistics, Public Health and Health Services, Epidemiology
Published
2018

14. Smokeless Tobacco Use and Prevalence of Cardiovascular Disease Among Males in the Population Assessment of Tobacco and Health (PATH) Study, Waves 1–4

Author

Nahhas, Georges J., Cummings, K. Michael, Halenar, Michael J., Sharma, Eva, Alberg, Anthony J., Hatuskami, Dorothy, Bansal-Travers, Maansi, Hyland, Andrew, Gaalema, Diann E., Morris, Pamela B., Duffy, Kara, Chang, Joanne T., Lagaud, Guy, Vivar, Juan C., Marshall, Daniela, Blanco, Carlos, and Taylor, Kristie A.

Published
2022
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18. Factors Associated with Head and Neck Cancer Postoperative Radiotherapy Delays: A Systematic Review and Meta‐analysis.

Author

Duckett, Kelsey A., Kassir, Mohamed Faisal, Nguyen, Shaun A., Brennan, Emily A., Chera, Bhisham S., Sterba, Katherine R., Halbert, Chanita Hughes, Hill, Elizabeth G., McCay, Jessica, Puram, Sidharth V., Jackson, Ryan S., Sandulache, Vlad C., Kahmke, Russel, Osazuwa‐Peters, Nosayaba, Ramadan, Salma, Nussenbaum, Brian, Alberg, Anthony J., and Graboyes, Evan M.

Abstract

Objective: Initiating postoperative radiotherapy (PORT) within 6 weeks of surgery for head and neck squamous cell carcinoma (HNSCC) is included in the National Comprehensive Cancer Network Clincal Practice Guidelines and is a Commission on Cancer quality metric. Factors associated with delays in starting PORT have not been systematically described nor synthesized. Data Sources: PubMed, Scopus, and CINAHL. Review Methods: We included studies describing demographic characteristics, clinical factors, or social determinants of health associated with PORT delay (>6 weeks) in patients with HNSCC treated in the United States after 2003. Meta‐analysis of odds ratios (ORs) was performed on nonoverlapping datasets. Results: Of 716 unique abstracts reviewed, 21 studies were included in the systematic review and 15 in the meta‐analysis. Study sample size ranged from 19 to 60,776 patients. In the meta‐analysis, factors associated with PORT delay included black race (OR, 1.46, 95% confidence interval [CI]: 1.28‐1.67), Hispanic ethnicity (OR, 1.37, 95% CI, 1.17‐1.60), Medicaid or no health insurance (OR, 2.01, 95% CI, 1.90‐2.13), lower income (OR, 1.38, 95% CI, 1.20‐1.59), postoperative admission >7 days (OR, 2.92, 95% CI, 2.31‐3.67), and 30‐day hospital readmission (OR, 1.37, 95% CI, 1.29‐1.47). Conclusion: Patients at greatest risk for a delay in initiating guideline‐adherent PORT include those who are from minoritized communities, of lower socioeconomic status, and experience postoperative challenges. These findings provide the foundational evidence needed to deliver targeted interventions to enhance equity and quality in HNSCC care delivery. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Neighborhood-Level Disadvantage and Delayed Adjuvant Therapy in Head and Neck Cancer

Author

Graboyes, Evan M., primary, Cagle, Joshua Lee, additional, Ramadan, Salma, additional, Prasad, Kavita, additional, Yan, Flora, additional, Pearce, John, additional, Mazul, Angela L., additional, Anoma, Jean-Sebastien, additional, Hill, Elizabeth G., additional, Chera, Bhisham S., additional, Puram, Sidharth V., additional, Jackson, Ryan, additional, Sandulache, Vlad C., additional, Tam, Samantha, additional, Topf, Michael C., additional, Kahmke, Russel, additional, Osazuwa-Peters, Nosayaba, additional, Nussenbaum, Brian, additional, Alberg, Anthony J., additional, Sterba, Katherine R., additional, and Halbert, Chanita Hughes, additional

Published
2024
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21. Author Reply to Letter by Topkan et al Regarding Delays in Starting Postoperative Radiotherapy

Author

Duckett, Kelsey A., primary, Lee, Byung Joo, additional, Chera, Bhisham S., additional, Puram, Sidharth V., additional, Sandulache, Vlad C., additional, Kahmke, Russel, additional, Nguyen, Shaun A., additional, Nussenbaum, Brian, additional, Alberg, Anthony J., additional, Halbert, Chanita Hughes, additional, Sterba, Katherine R., additional, and Graboyes, Evan M., additional

Published
2024
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26. Carotenoids, retinol, tocopherols, and prostate cancer risk: pooled analysis of 15 studies 1–3

Author

Key, Timothy J, Appleby, Paul N, Travis, Ruth C, Albanes, Demetrius, Alberg, Anthony J, Barricarte, Aurelio, Black, Amanda, Boeing, Heiner, Bueno-de-Mesquita, H Bas, Chan, June M, Chen, Chu, Cook, Michael B, Donovan, Jenny L, Galan, Pilar, Gilbert, Rebecca, Giles, Graham G, Giovannucci, Edward, Goodman, Gary E, Goodman, Phyllis J, Gunter, Marc J, Hamdy, Freddie C, Heliövaara, Markku, Helzlsouer, Kathy J, Henderson, Brian E, Hercberg, Serge, Hoffman-Bolton, Judy, Hoover, Robert N, Johansson, Mattias, Khaw, Kay-Tee, King, Irena B, Knekt, Paul, Kolonel, Laurence N, Le Marchand, Loic, Männistö, Satu, Martin, Richard M, Meyer, Haakon E, Mondul, Alison M, Moy, Kristin A, Neal, David E, Neuhouser, Marian L, Palli, Domenico, Platz, Elizabeth A, Pouchieu, Camille, Rissanen, Harri, Schenk, Jeannette M, Severi, Gianluca, Stampfer, Meir J, Tjønneland, Anne, Touvier, Mathilde, Trichopoulou, Antonia, Weinstein, Stephanie J, Ziegler, Regina G, Zhou, Cindy Ke, Allen, Naomi E, Biomarkers, Endogenous Hormones Nutritional, and Group, Prostate Cancer Collaborative

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Prevention, Urologic Diseases, Nutrition, Prostate Cancer, Cancer, Aging, Clinical Research, Adult, Biomarkers, Carotenoids, Case-Control Studies, Cohort Studies, Cross-Sectional Studies, Humans, Lycopene, Male, Meta-Analysis as Topic, Middle Aged, Neoplasm Grading, Neoplasm Staging, Observational Studies as Topic, Prospective Studies, Prostate, Prostatic Neoplasms, Risk Factors, Vitamin A, alpha-Tocopherol, prostate cancer, carotenoids, retinol, tocopherols, vitamin E, vitamin A, pooled analysis, nested case-control study, biomarkers, Endogenous Hormones Nutritional Biomarkers Prostate Cancer Collaborative Group, Engineering, Medical and Health Sciences, Nutrition & Dietetics, Clinical sciences, Nutrition and dietetics
Abstract

BackgroundIndividual studies have suggested that circulating carotenoids, retinol, or tocopherols may be associated with prostate cancer risk, but the studies have not been large enough to provide precise estimates of associations, particularly by stage and grade of disease.ObjectiveThe objective of this study was to conduct a pooled analysis of the associations of the concentrations of 7 carotenoids, retinol, α-tocopherol, and γ-tocopherol with risk of prostate cancer and to describe whether any associations differ by stage or grade of the disease or other factors.DesignPrincipal investigators of prospective studies provided individual participant data for prostate cancer cases and controls. Risk by study-specific fifths of each biomarker was estimated by using multivariable-adjusted conditional logistic regression in matched case-control sets.ResultsData were available for up to 11,239 cases (including 1654 advanced stage and 1741 aggressive) and 18,541 controls from 15 studies. Lycopene was not associated with overall risk of prostate cancer, but there was statistically significant heterogeneity by stage of disease, and the OR for aggressive disease for the highest compared with the lowest fifth of lycopene was 0.65 (95% CI: 0.46, 0.91; P-trend = 0.032). No other carotenoid was significantly associated with overall risk of prostate cancer or with risk of advanced-stage or aggressive disease. For retinol, the OR for the highest compared with the lowest fifth was 1.13 (95% CI: 1.04, 1.22; P-trend = 0.015). For α-tocopherol, the OR for the highest compared with the lowest fifth was 0.86 (95% CI: 0.78, 0.94; P-trend < 0.001), with significant heterogeneity by stage of disease; the OR for aggressive prostate cancer was 0.74 (95% CI: 0.59, 0.92; P-trend = 0.001). γ-Tocopherol was not associated with risk.ConclusionsOverall prostate cancer risk was positively associated with retinol and inversely associated with α-tocopherol, and risk of aggressive prostate cancer was inversely associated with lycopene and α-tocopherol. Whether these associations reflect causal relations is unclear.

Published
2015

27. Prediagnostic Proinflammatory Dietary Potential Is Associated with All-Cause Mortality among African-American Women with High-Grade Serous Ovarian Carcinoma

Author

Peres, Lauren C, Hebert, James R, Qin, Bo, Guertin, Kristin A, Bandera, Elisa V, Shivappa, Nitin, Camacho, Tareq F, Chyn, Deanna, Alberg, Anthony J, Barnholtz-Sloan, Jill S, Bondy, Melissa L, Cote, Michele L, Funkhouser, Ellen, Moorman, Patricia G, Peters, Edward S, Schwartz, Ann G, Terry, Paul D, and Schildkraut, Joellen M

Published
2019
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29. Development and Evaluation of a Navigation-Based, Multilevel Intervention to Improve the Delivery of Timely, Guideline-Adherent Adjuvant Therapy for Patients With Head and Neck Cancer

Author

Graboyes, Evan M., Sterba, Katherine R., Li, Hong, Warren, Graham W., Alberg, Anthony J., Calhoun, Elizabeth A., Nussenbaum, Brian, McCay, Jessica, Marsh, Courtney H., Osazuwa-Peters, Nosayaba, Neskey, David M., Kaczmar, John M., Sharma, Anand K., Harper, Jennifer, Day, Terry A., and Hughes-Halbert, Chanita

Published
2021
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33. Tubal ligation and ovarian cancer risk in African American women

Author

McNamara, Chrissy, Abbott, Sarah E., Bandera, Elisa V., Qin, Bo, Peres, Lauren C., Camacho, Fabian, Moorman, Patricia G., Alberg, Anthony J., Barnholtz-Sloan, Jill S., Bondy, Melissa, Cote, Michele L., Funkhouser, Ellen, Peters, Edward S., Schwartz, Ann G., Schildkraut, Joellen M., and Terry, Paul

Published
2017

34. Cigarette smoking and the association with serous ovarian cancer in African American women : African American Cancer Epidemiology Study (AACES)

Author

Kelemen, Linda E., Abbott, Sarah, Qin, Bo, Peres, Lauren Cole, Moorman, Patricia G., Wallace, Kristin, Bandera, Elisa V., Barnholtz-Sloan, Jill S., Bondy, Melissa, Cartmell, Kathleen, Cote, Michele L., Funkhouser, Ellen, Paddock, Lisa E., Peters, Edward S., Schwartz, Ann G., Terry, Paul, Alberg, Anthony J., and Schildkraut, Joellen M.

Published
2017

36. Patient Navigation for Timely, Guideline-Adherent Adjuvant Therapy for Head and Neck Cancer: A National Landscape Analysis

Author

Graboyes, Evan M., primary, Chappell, Michelle, additional, Duckett, Kelsey A., additional, Sterba, Katherine, additional, Hughes Halbert, Chanita, additional, Hill, Elizabeth G., additional, Chera, Bhishamjit, additional, McCay, Jessica, additional, Puram, Sidharth V., additional, Ramadan, Salma, additional, Sandulache, Vlad C., additional, Kahmke, Russel, additional, Nussenbaum, Brian, additional, Alberg, Anthony J., additional, Paskett, Electra D., additional, and Calhoun, Elizabeth, additional

Published
2023
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37. The Association between Mediated Deprivation and Ovarian Cancer Survival among African American Women

Author

Lawson, Andrew B., primary, Kim, Joanne, additional, Johnson, Courtney, additional, Ratnapradipa, Kendra L., additional, Alberg, Anthony J., additional, Akonde, Maxwell, additional, Hastert, Theresa, additional, Bandera, Elisa V., additional, Terry, Paul, additional, Mandle, Hannah, additional, Cote, Michele L., additional, Bondy, Melissa, additional, Marks, Jeffrey, additional, Peres, Lauren C., additional, Schildkraut, Joellen, additional, and Peters, Edward S., additional

Published
2023
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40. BMI, physical activity, and breast cancer subtype in white, black, and Sea Island breast cancer survivors

Author

Ford, Marvella E., primary, Bauza, Colleen E., additional, Findlay, Victoria J., additional, Turner, David P., additional, Abraham, Latecia M., additional, Moore, Leslie A., additional, Magwood, Gayenell, additional, Alberg, Anthony J., additional, Gaymon, Kadeidre, additional, Knight, Kendrea D., additional, Hilton, Ebony, additional, Malek, Angela M., additional, Kramer, Rita M., additional, Peterson, Lindsay L., additional, Gregoski, Mathew J., additional, Bolick, Susan, additional, Hurley, Deborah, additional, Mosley, Catishia, additional, Hazelton, Tonya R., additional, Burshell, Dana R., additional, Nogueira, Lourdes, additional, Mack, Franshawn, additional, Brown, Erika T., additional, Salley, Judith D., additional, Whitfield, Keith E., additional, Esnaola, Nestor F., additional, and Cunningham, Joan E., additional

Published
2020
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49. Delays Starting Postoperative Radiotherapy Among Head and Neck Cancer Patients: A Systematic Review and Meta‐analysis.

Author

Duckett, Kelsey A., Kassir, Mohamed Faisal, Nguyen, Shaun A., Brennan, Emily A., Chera, Bhishamjit S., Sterba, Katherine R., Hughes Halbert, Chanita, Hill, Elizabeth G., McCay, Jessica, Puram, Sidharth V., Sandulache, Vlad C., Kahmke, Russel, Ramadan, Salma, Nussenbaum, Brian, Alberg, Anthony J., and Graboyes, Evan M.

Abstract

Objective: Initiating postoperative radiotherapy (PORT) within 6 weeks (42 days) of surgery is the first and only Commission on Cancer (CoC) approved quality metric for head and neck squamous cell carcinoma (HNSCC). No study has systematically reviewed nor synthesized the literature to establish national benchmarks for delays in starting PORT. Data Sources: Following Preferred Reporting Items for Systematic Reviews and Meta‐analyses guidelines, we performed a systematic review of PubMed, Scopus, and CINAHL. Review Methods: Studies that described time‐to‐PORT or PORT delays in patients with HNSCC treated in the United States after 2003 were included. Meta‐analysis of proportions and continuous measures was performed on nonoverlapping datasets to examine the pooled frequency of PORT delays and time‐to‐PORT. Results: Thirty‐six studies were included in the systematic review and 14 in the meta‐analysis. Most studies utilized single‐institution (n = 17; 47.2%) or cancer registry (n = 16; 44.4%) data. Twenty‐five studies (69.4%) defined PORT delay as >6 weeks after surgery (the definition utilized by the CoC and National Comprehensive Cancer Network Guidelines), whereas 4 (11.1%) defined PORT delay as a time interval other than >6 weeks, and 7 (19.4%) characterized time‐to‐PORT without defining delay. Meta‐analysis revealed that 48.6% (95% confidence interval [CI], 41.4‐55.9) of patients started PORT > 6 weeks after surgery. Median and mean time‐to‐PORT were 45.8 (95% CI, 42.4‐51.4 days) and 47.4 days (95% CI, 43.4‐51.4 days), respectively. Conclusion: Delays in initiating guideline‐adherent PORT occur in approximately half of patients with HNSCC. These meta‐analytic data can be used to set national benchmarks and assess progress in reducing delays. [ABSTRACT FROM AUTHOR]

Published
2024
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