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14 results on '"Alba-Loureiro, Tatiana C."'

1. Early inflammatory response mediated by Angiotensin II in cardiac arteries of normotensive mice

Author

Oliveira, Thais Cristina de Souza, primary, Viegas, Katia Aparecida da Silva, additional, Lima, Rariane Silva de, additional, Alba-Loureiro, Tatiana C., additional, Lima, Cintia Taniguti, additional, Campos, Luciene Cristina Gastalho, additional, Barauna, Valerio Garrone, additional, Curi, Rui, additional, Irigoyen, Maria Claudia, additional, and Lacchini, Silvia, additional

Published
2023
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4. Profiling plasma‐extracellular vesicle proteins and microRNAs in diabetes onset in middle‐aged male participants in the ELSA‐Brasil study

Author

Masi, Laureane N., primary, Lotufo, Paulo A., additional, Ferreira, Frederico M., additional, Rodrigues, Alice C., additional, Serdan, Tamires D. A., additional, Souza‐Siqueira, Talita, additional, Braga, Aécio A., additional, Saldarriaga, Magda E. G., additional, Alba‐Loureiro, Tatiana C., additional, Borges, Fernanda T., additional, Cury, Diego P., additional, Hirata, Mario H., additional, Gorjão, Renata, additional, Pithon‐Curi, Tania C., additional, Lottenberg, Simão A., additional, Fedeli, Ligia M. G., additional, Nakaya, Helder T. I., additional, Bensenor, Isabela J. M., additional, Curi, Rui, additional, and Hirabara, Sandro M., additional

Published
2021
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6. Attenuation of obesity and insulin resistance by fish oil supplementation is associated with improved skeletal muscle mitochondrial function in mice fed a high-fat diet

Author

Martins, Amanda R., primary, Crisma, Amanda R., additional, Masi, Laureane N., additional, Amaral, Catia L., additional, Marzuca-Nassr, Gabriel N., additional, Bomfim, Lucas H.M., additional, Teodoro, Bruno G., additional, Queiroz, André L., additional, Serdan, Tamires D.A., additional, Torres, Rosangela P., additional, Mancini-Filho, Jorge, additional, Rodrigues, Alice C., additional, Alba-Loureiro, Tatiana C., additional, Pithon-Curi, Tania C., additional, Gorjao, Renata, additional, Silveira, Leonardo R., additional, Curi, Rui, additional, Newsholme, Philip, additional, and Hirabara, Sandro M., additional

Published
2018
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7. La Inactividad Física en Etapas Tempranas del Desarrollo Disminuye la Expresión de Akt en el Músculo Sóleo de Ratas

Author

Marquez, Jose L., Sandro Massao Hirabara, Fiamoncini, Jarlei, Hatanaka, Elaine, Alba-Loureiro, Tatiana C., Lima-Salgado, Thais M., Curi, Rui, and Salazar, Luis A.

Subjects
Physical inactivity, Inactividad física, Akt, Insulin resistance, Insulinoresistencia
Abstract

El Síndrome Metabólico corresponde a una serie de trastornos relacionados con obesidad e inactividad física. Poco se conoce respecto de la falta de ejercicio, en estadios tempranos del desarrollo, en la susceptibilidad a un fenotipo insulinoresistente inducido por una dieta alta en grasas. Akt juega un rol clave en la síntesis de proteínas y el transporte de glucosa en el músculo esquelético y ha mostrado ser regulada por la actividad muscular. El objetivo del presente estudio fue determinar el efecto de la inactividad física temprana sobre el crecimiento muscular y la susceptibilidad de adquirir un fenotipo diabético y evaluar su relación con la expresión de Akt. Cuarenta ratas Wistar fueron distribuidas en 2 grupos (Grupos Control, Std) y Restricción de movimiento (RM). Entre los días postnatal 23 y 70 los animales del grupo RM fueron alojados en pequeñas jaulas que no permitían una actividad motora relevante. A partir del día postnatal 71 y hasta el día 102, 10 ratas de cada grupo fueron alimentadas con una Dieta Alta en Grasas (RM-DAG y Std-DAG). No se observaron diferencias en el peso corporal total pero DAG generó un significativo incremento en la grasa epididimal. RM generó una disminución significativa en el peso de los músculos sóleo. La captación de glucosa estimulada por insulina fue menor en el grupo RM-DAG. Los niveles de proteína Akt fueron menores en los grupos RM. El análisis de PCR a tiempo real mostró que la restricción de movimiento disminuyó los niveles de ARNm de AKT1 en el músculo sóleo, independiente de la dieta administrada. Estos hallazgos sugieren que la inactividad física temprana limita el crecimiento muscular y contribuye en la instauración un fenotipo insulino resistente, lo cual puede ser en parte explicado por una desregulación en la expresión de Akt. Metabolic Syndrome is a group of conditions related to obesity and physical inactivity. Little is known about the role of physical inactivity, in early stages of development, in the susceptibility to insulin resistant phenotype induced by high fat diet. Akt plays a key role in protein synthesis and glucose transport in skeletal muscle and has been regulated by muscle activity. The objective of present study was to determine the effect of early physical inactivity on muscle growth and susceptibility to acquire a diabetic phenotype and to assess its relationship with Akt expression. Forty Wistar male rats were distributed in two groups (standard group, Std) and movement restriction (RM). Between days 23 and 70 after birth, RM group was kept in small cages that did not allow them to perform relevant motor activity. From day 71 to 102 after birth, 10 rats of each group were fed with hyperlipidic diet (groups Std-DAG and RM-DAG). No differences were observed in total body weight although DAG increased epididymal fat pad weight. RM decreased significantly the soleus weight. Insulin-mediated glucose uptake was lower in RM-DAG group. Akt protein levels were lower in RM groups. Real time RT-PCR analysis showed that movement restriction decreased mRNA levels of AKT1 in soleus muscle, regardless of supplied diet. These findings suggest that early physical inactivity limits muscle's growth and contributes to instauration of insulin resistant phenotype, which can be partly explained by dysregulation of Akt expression.

Published
2011

8. Differences in age modulates neutrophils function

Author

Lagranha, Claudia J., primary, Alba-Loureiro, Tatiana C., additional, da Silva, Aline Isabel, additional, de Lima, Danuta Duarte Bezerra, additional, Pedroza, Anderson Apolonio, additional, Ferreira, Diorginis, additional, and Pithon-Curi, Tania, additional

Published
2014
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9. Correction: Glutamine Supplementation Stimulates Protein-Synthetic and Inhibits Protein-Degradative Signaling Pathways in Skeletal Muscle of Diabetic Rats

Author

Lambertucci, Adriana C., primary, Lambertucci, Rafael H., additional, Hirabara, Sandro M., additional, Curi, Rui, additional, Moriscot, Anselmo S., additional, Alba-Loureiro, Tatiana C., additional, Guimarães-Ferreira, Lucas, additional, Levada-Pires, Adriana C., additional, Vasconcelos, Diogo A. A., additional, Sellitti, Donald F., additional, and Pithon-Curi, Tania C., additional

Published
2013
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10. Glutamine Supplementation Stimulates Protein-Synthetic and Inhibits Protein-Degradative Signaling Pathways in Skeletal Muscle of Diabetic Rats

Author

Lambertucci, Adriana C., primary, Lambertucci, Rafael H., additional, Hirabara, Sandro M., additional, Curi, Rui, additional, Moriscot, Anselmo S., additional, Alba-Loureiro, Tatiana C., additional, Guimarães-Ferreira, Lucas, additional, Levada-Pires, Adriana C., additional, Vasconcelos, Diogo A. A., additional, Sellitti, Donald F., additional, and Pithon-Curi, Tania C., additional

Published
2012
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14. Sympathetic hyperactivity differentially affects skeletal muscle mass in developing heart failure: role of exercise training

Author

Bacurau, Aline V. N., primary, Jardim, Maíra A., additional, Ferreira, Julio C. B., additional, Bechara, Luiz R. G., additional, Bueno, Carlos R., additional, Alba-Loureiro, Tatiana C., additional, Negrao, Carlos E., additional, Casarini, Dulce E., additional, Curi, Rui, additional, Ramires, Paulo R., additional, Moriscot, Anselmo S., additional, and Brum, Patricia C., additional

Published
2009
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