144 results on '"Alarcon, Balbino"'
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2. A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
3. Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen
4. SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation
5. Multivalent Structure of an α β T Cell Receptor
6. Physiological and therapeutic relevance of T cell receptor-mediated antigen trogocytosis
7. A Cholesterol-Based Allostery Model of T Cell Receptor Phosphorylation
8. Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains
9. Crammed signaling motifs in the T-cell receptor
10. The CD3 Conformational Change in the γδ T Cell Receptor Is Not Triggered by Antigens but Can Be Enforced to Enhance Tumor Killing
11. Conformational Model
12. Dissecting molecular mechanisms underlying T cell co-potentiation when targeting the TCR/CD3 complex with anti-CD3 Fab fragments
13. MTOC Translocation Modulates IS Formation and Controls Sustained T Cell Signaling
14. T Cell Receptor Internalization from the Immunological Synapse Is Mediated by TC21 and RhoG GTPase-Dependent Phagocytosis
15. H-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunity
16. Increased Sensitivity of Antigen-Experienced T Cells through the Enrichment of Oligomeric T Cell Receptor Complexes
17. Impacts of TCR-Nck Interaction Inhibitors on T Cell Activation Driven By Mixed Lymphocyte Reactions
18. A Conformational Change Senses the Strength of T Cell Receptor-Ligand Interaction during Thymic Selection
19. Longitudinal dynamics of SARS-CoV-2-specific cellular and humoral immunity after natural infection or BNT162b2 vaccination
20. Editorial: Cytoskeletal Regulation of Immune Response
21. Interaction between the N-terminal SH3 domain of Nckα and CD3ɛ-derived peptides: Non-canonical and canonical recognition motifs
22. Evolutionary Relationship between the T3 Chains of the T-Cell Receptor Complex and the Immunoglobulin Supergene Family
23. Challenges of T-Cell Therapy
24. DECREASED BREADTH OF THE ANTIBODY RESPONSE TO THE SPIKE PROTEIN OF SARS-CoV-2 AFTER REPEATED VACCINATION
25. Role of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling
26. The extracellular part of ζ is buried in the T cell antigen receptor complex
27. Toward Sézary Syndrome immunotherapy
28. Astrocyte to microglia cross-talk in acute and chronic neuroinflammation is shaped by SFRP1
29. Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3
30. A native antibody-based mobility-shift technique (NAMOS-assay) to determine the stoichiometry of multiprotein complexes
31. Long-Term Effect of the TCR-Nck Interaction Inhibitor AX-024 on GvHD in a Human Xenogeneic Model
32. Overlapping functions of human CD3δ and mouse CD3γ in αβ T-cell development revealed in a humanized CD3γ-deficient mouse
33. A conformation- and avidity-based proofreading mechanism for the TCR–CD3 complex
34. Recruitment of Nck by CD3(epsilon) reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation
35. Small molecule AX-024 targets T cell receptor signaling by disrupting CD3ε-Nck interaction
36. Molecular mechanisms underlying T cell co-potentiation by anti-CD3 Fab fragments
37. Diacylglycerol kinase ζ promotes actin cytoskeleton remodeling and mechanical forces at the B cell immune synapse
38. SFRP1 shapes astrocyte to microglia cross-talk in acute and chronic neuroinflammation
39. CD3δ couples T-cell receptor signalling to ERK activation and thymocyte positive selection
40. Multivalent structure of an alpha-beta-T cell receptor
41. Ligand-induced conformational change in the T-cell receptor associated with productive immune synapses
42. CD3δ deficiency arrests development of the αβ but not the γδ T cell lineage
43. Engaged and Bystander T Cell Receptors Are Down-modulated by Different Endocytotic Pathways
44. An endoplasmic reticulum retention signal in the CD3 epsilon chain of the T-cell receptor
45. 367 - Impacts of TCR-Nck Interaction Inhibitors on T Cell Activation Driven By Mixed Lymphocyte Reactions
46. Antigen Presentation between T Cells Drives Th17 Polarization Under Conditions of Limiting Antigen
47. The TCR is an allosterically regulated macromolecular machinery changing its conformation while working
48. RRAS2 shapes the TCR repertoire by setting the threshold for negative selection
49. T Cell Receptor-mediated Signal Transduction Controlled by the β Chain Transmembrane Domain: APOPTOSIS-DEFICIENT CELLS DISPLAY UNBALANCED MITOGEN-ACTIVATED PROTEIN KINASES ACTIVITIES UPON T CELL RECEPTOR ENGAGEMENT
50. Intracellular Redistribution of Nucleolin upon Interaction with the CD3ε Chain of the T Cell Receptor Complex
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