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3. Predictors of outcome and symptomatic intracranial hemorrhage in acute basilar artery occlusions: Analysis of the PC-SEARCH thrombectomy registry.

Author

Mierzwa, Adam T, Nelson, Ashley, Kasab, Sami Al, Ortega Gutierrez, Santiago, Vivanco-Suarez, Juan, Farooqui, Mudassir, Jadhav, Ashutosh P, Desai, Shashvat, Toth, Gabor, Alrohimi, Anas, Nguyen, Thanh N, Klein, Piers, Abdalkader, Mohamad, Salahuddin, Hisham, Pandey, Aditya, Wilseck, Zachary, Koduri, Sravanthi, Vora, Niraj, Aladamat, Nameer, and Gharaibeh, Khaled

Published
2024
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6. Abstract WP183: Intracranial Atherosclerotic Disease in Acute Basilar Artery Occlusion

Author

Mierzwa, Adam T, primary, Al Kasab, Sami, additional, Nelson, Ashley, additional, Ortega, Santiago, additional, Vivanco-Suarez, Juan, additional, Farooqui, Mudassir, additional, Jadhav, Ashutosh P, additional, Desai, Shashvat, additional, Toth, Gabor, additional, Alrohimi, Anas, additional, Nguyen, Thanh, additional, Klein, Piers, additional, AbdalKader, Mohamad, additional, Pandey, Aditya, additional, Koduri, Sravanthi, additional, Vora, Shivangi, additional, Aladamat, Nameer, additional, Gharaibeh, Khaled, additional, Afreen, Ehad, additional, Zaidi, Syed, additional, and Jumaa, Mouhammad A, additional

Published
2024
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7. Early and late basilar artery thrombectomy time window outcomes

Author

Mierzwa, Adam T., primary, Rao, Rahul, additional, Al Kasab, Sami, additional, Nelson, Ashley, additional, Ortega-Gutierrez, Santiago, additional, Vivanco-Suarez, Juan, additional, Farooqui, Mudassir, additional, Jadhav, Ashutosh P., additional, Desai, Shashvat, additional, Toth, Gabor, additional, Alrohimi, Anas, additional, Nguyen, Thanh N., additional, Klein, Piers, additional, Abdalkader, Mohamad, additional, Salahuddin, Hisham, additional, Pandey, Aditya, additional, Wilseck, Zachary, additional, Koduri, Sravanthi, additional, Vora, Nirav, additional, Aladamat, Nameer, additional, Gharaibeh, Khaled, additional, Afreen, Ehad, additional, Zaidi, Syed, additional, and Jumaa, Mouhammad, additional

Published
2024
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10. Acute Basilar Artery Occlusion Thrombectomy Performed in Early (<6 hours) and Late Time Window (>6 hours) from the PC-SEARCH Registry (S24.002)

Author

Aladamat, Nameer, primary, Mierzwa, Adam, additional, Zaidi, Syed, additional, Gharaibeh, Khaled, additional, Afreen, Ehad, additional, Al Kasab, Sami, additional, Nelson, Ashley, additional, Farooqui, Mudassir, additional, Suarez, Juan Vivanco, additional, Jadhav, Ashutosh, additional, Desai, Shashvat, additional, Toth, Gabor, additional, Alrohimi, Anas, additional, Nguyen, Thanh, additional, Piers, Klein, additional, Abdalkader, Mohamad, additional, Pandey, Aditya, additional, Koduri, Sravanthi, additional, Vora, Nirav, additional, Vora, Shivangi, additional, Jumaa, Mouhammad, additional, and Gutierrez, Santiago Ortega, additional

Published
2023
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11. Predictors of good outcome in Acute stroke due to basilar artery occlusion from the PC-SEARCH Registry (S24.005)

Author

Mierzwa, Adam, primary, Zaidi, Syed, additional, Aladamat, Nameer, additional, Gharaibeh, Khaled, additional, Afreen, Ehad, additional, Al Kasab, Sami, additional, Nelson, Ashley, additional, Gutierrez, Santiago Ortega, additional, Suarez, Juan Vivanco, additional, Farooqui, Mudassir, additional, Jadhav, Ashutosh, additional, Desai, Shashvat, additional, Toth, Gabor, additional, Alrohimi, Anas, additional, Nguyen, Thanh, additional, Piers, Klein, additional, Abdalkader, Mohamad, additional, Salahuddin, Hisham, additional, Pandey, Aditya, additional, Koduri, Sravanthi, additional, vora, Nirav, additional, and Jumaa, Mouhammad, additional

Published
2023
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12. Intra-Arterial Thrombolysis Associated with Symptomatic Intracranial Hemorrhage in Acute Basilar Artery Thrombectomy, PC-SEARCH Registry Analysis (P8-5.008)

Author

Mierzwa, Adam, primary, Zaidi, Syed, additional, Gharaibeh, Khaled, additional, Aladamat, Nameer, additional, Afreen, Ehad, additional, Al Kasab, Sami, additional, Nelson, Ashley, additional, Gutierrez, Santiago Ortega, additional, Farooqui, Mudassir, additional, Vivanco-Suarez, Juan, additional, Jadhav, Ashutosh, additional, Desai, Shashvat, additional, Toth, Gabor, additional, Alrohimi, Anas, additional, Nguyen, Thanh, additional, Piers, Klein, additional, Abdalkader, Mohamad, additional, Pandey, Aditya, additional, Koduri, Sravanthi, additional, Vora, Shivangi, additional, Vora, Nirav, additional, and Jumaa, Mouhammad, additional

Published
2023
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15. Safety Profile of Rescue Stenting Following Thrombectomy for Acute Basilar Artery Occlusion – PC SEARCH Registry Analysis (P7-5.002)

Author

Afreen, Ehad, primary, Mierzwa, Adam, additional, Zaidi, Syed, additional, Aladamat, Nameer, additional, Gharaibeh, Khaled, additional, Nelson, Ashley, additional, Gutierrez, Santiago Ortega, additional, Farooqui, Mudassir, additional, Vivanco-Suarez, Juan, additional, Jadhav, Ashutosh, additional, Desai, Shashvat, additional, Toth, Gabor, additional, Alrohimi, Anas, additional, Nguyen, Thanh, additional, Piers, Klein, additional, Abdalkader, Mohamad, additional, Pandey, Aditya, additional, Koduri, Sravanthi, additional, Vora, Shivangi, additional, Vora, Nirav, additional, Jumaa, Mouhammad, additional, and Al Kasab, Sami, additional

Published
2023
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17. Transient headache and neurological deficits with cerebrospinal fluid lymphocytosis syndrome: A comprehensive systematic review of 93 patients from 57 studies

Author

Al-Chalabi, Mustafa, primary, Hegde, Prajwal, additional, Asghar, Fahham, additional, Aladamat, Nameer, additional, Delcimmuto, Nicholas, additional, Gharaibeh, Khaled, additional, Samara, Mohammad, additional, Esengul, Yasar, additional, Mahfooz, Naeem, additional, and Sheikh, Ajaz, additional

Published
2023
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18. Stroke Thrombectomy and Right Atrial Clot Aspiration in 29 Year Old Woman

Author

Rao, Rahul, Aladamat, Nameer, Robbins, Sarah, Jumaa, Mouhammad, and Zaidi, Syed

Abstract

We present a case report of a previously healthy 29 year old woman who developed thromboembolic events in rapid fashion after a recent orthopedic surgery. This case highlights the importance of understanding risk factors for clot formation even in those who had no prior events, the efficacy of novel aspiration techniques to remove emboli, and how rapid triaging of acute symptoms can lead to the best outcomes. She presented to the emergency department with shortness of breath and was found to have a large bilateral pulmonary embolus. She was given intravenous thrombolysis. Shortly after, she developed aphasia and right-sided weakness and was taken emergently for mechanical thrombectomy of a left middle cerebral artery occlusion. She was later found to have a patent foramen ovale and a highly mobile right atrial thrombus which was aspirated. Further evaluation revealed right lower extremity peroneal and popliteal deep venous thrombi. She was placed on anticoagulation, made a full clinical recovery, and was discharged home. Prompt recognition of symptoms, efficient in-hospital work flow, and a multidisciplinary approach led to an outstanding outcome in this young patient.

Published
2024
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19. Comparing Functional Outcomes and Safety Profiles of First-Line Aspiration Thrombectomy Versus Stentriever for Acute Basilar Artery Occlusion: Propensity Analysis of the PC-SEARCH Thrombectomy Registry.

Author

Mierzwa, Adam T., Al Kasab, Sami, Nelson, Ashley, Ortega Gutierrez, Santiago, Vivanco-Suarez, Juan, Farooqui, Mudassir, Jadhav, Ashutosh P., Desai, Shashvat, Toth, Gabor, Alrohimi, Anas, Thanh N. Nguyen, Klein, Piers, Abdalkader, Mohamad, Salahuddin, Hisham, Pandey, Aditya, Koduri, Sravanthi, Vora, Niraj, Aladamat, Nameer, Gharaibeh, Khaled, and Afreen, Ehad

Published
2023
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20. sj-pdf-1-cep-10.1177_03331024231157694 - Supplemental material for Transient headache and neurological deficits with cerebrospinal fluid lymphocytosis syndrome: A comprehensive systematic review of 93 patients from 57 studies

Author

Al-Chalabi, Mustafa, Hegde, Prajwal, Asghar, Fahham, Aladamat, Nameer, Delcimmuto, Nicholas, Gharaibeh, Khaled, Samara, Mohammad, Esengul, Yasar, Mahfooz, Naeem, and Sheikh, Ajaz

Subjects
FOS: Psychology, FOS: Clinical medicine, 170199 Psychology not elsewhere classified, 110319 Psychiatry (incl. Psychotherapy), 110306 Endocrinology, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, sj-pdf-1-cep-10.1177_03331024231157694 for Transient headache and neurological deficits with cerebrospinal fluid lymphocytosis syndrome: A comprehensive systematic review of 93 patients from 57 studies by Mustafa Al-Chalabi, Prajwal Hegde, Fahham Asghar, Nameer Aladamat, Nicholas Delcimmuto, Khaled Gharaibeh, Mohammad Samara, Yasar Esengul, Naeem Mahfooz and Ajaz Sheikh in Cephalalgia

Published
2023
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22. Triglyceride-Glucose Index for Early Prediction of Nonalcoholic Fatty Liver Disease: A Meta-Analysis of 121,975 Individuals

Author

Beran, Azizullah, primary, Ayesh, Hazem, additional, Mhanna, Mohammed, additional, Wahood, Waseem, additional, Ghazaleh, Sami, additional, Abuhelwa, Ziad, additional, Sayeh, Wasef, additional, Aladamat, Nameer, additional, Musallam, Rami, additional, Matar, Reem, additional, Malhas, Saif-Eddin, additional, and Assaly, Ragheb, additional

Published
2022
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23. Balanced Crystalloids versus Normal Saline in Adults with Sepsis: A Comprehensive Systematic Review and Meta-Analysis

Author

Beran, Azizullah, primary, Altorok, Nehaya, additional, Srour, Omar, additional, Malhas, Saif-Eddin, additional, Khokher, Waleed, additional, Mhanna, Mohammed, additional, Ayesh, Hazem, additional, Aladamat, Nameer, additional, Abuhelwa, Ziad, additional, Srour, Khaled, additional, Mahmood, Asif, additional, Altorok, Nezam, additional, Taleb, Mohammad, additional, and Assaly, Ragheb, additional

Published
2022
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25. Mortality rate and biomarker expression within COVID-19 patients who develop acute ischemic stroke: a systematic review and meta-analysis

Author

Yassin, Ahmed, primary, Ghzawi, Ansam, additional, Al-Mistarehi, Abdel-Hameed, additional, El-Salem, Khalid, additional, Y Benmelouka, Amira, additional, M Sherif, Ahmed, additional, BenhadjDahman, Nesrine, additional, AlAdamat, Nameer, additional, Jemel, Amine, additional, Negida, Ahmed, additional, and Abdelmonem, Mohamed, additional

Published
2021
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26. Control-matched octo/nonagenarian outcomes in acute basilar artery occlusions treated with mechanical thrombectomy—analysis of the PC-SEARCH thrombectomy registry

Author

Mierzwa, Adam T, Prologo-Richardson, Paige, Kasab, Sami Al, Nelson, Ashley, Gutierrez, Santiago Ortega, Vivanco-Suarez, Juan, Farooqui, Mudassir, Jadhav, Ashutosh P, Desai, Shashvat, Toth, Gabor, Alrohimi, Anas, Nguyen, Thanh N, Klein, Piers, Abdalkader, Mohamad, Salahuddin, Hisham, Wilseck, Zachary, Pandey, Aditya, Koduri, Sravanthi, Vora, Nirav, Aladamat, Nameer, Gharaibeh, Khaled, Afreen, Ehad, Zaidi, Syed, and Jumaa, Mouhammad

Abstract

Introduction Age is often used as a predictor in determining outcomes in large vessel occlusions treated with mechanical thrombectomy. However, limited data exist for octo/nonagenarian outcomes compared to younger individuals in acute basilar artery occlusions treated with thrombectomy.Methods Patient data were obtained from the PC-SEARCH Thrombectomy Registry which consists of 444 acute basilar artery occlusions treated with mechanical thrombectomy. Individuals were dichotomized based on age (>80 and ≤80 years old). Primary outcome was defined as modified Rankin Scale of 0–3 at 90 days. Logistic and multivariate regression, as well as control-matched analysis, were performed.Results There were 373 and 71 patients in the younger and older cohorts, respectively. Gender, ethnicity, smoking status, atrial fibrillation, and coronary artery disease were noted to be significantly different between cohorts. At 90 days, 178 (47.7%) and 23 (32.4%) patients achieved primary outcome at 90 days (p = 0.02), however, after controlling for potentially confounding factors this association lost significance (OR 0.50 95% CI 0.24–1.05; p = 0.07). There were 84 patients included in the control matched analysis and demonstrated no significant differences on multivariate analysis between cohorts (OR 0.68 95% CI 0.25–1.84; p = 0.45).Interpretation Octa/nonagenarians presenting with an acute basilar artery occlusion treated with mechanical thrombectomy can achieve acceptable rates of favorable functional outcomes compared to younger individuals with similar baseline demographic and stroke characteristics.

Published
2024
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27. Thrombectomy Outcomes in Acute Basilar Artery Occlusions Due to Intracranial Atherosclerotic Disease.

Author

Mierzwa AT, Al Kasab S, Nelson A, Gutierrez SO, Vivanco-Suarez J, Farooqui M, Jadhav AP, Desai S, Toth G, Alrohimi A, Nguyen TN, Klein P, Abdalkader M, Salahuddin H, Pandey A, Koduri S, Wilseck Z, Vora N, Aladamat N, Gharaibeh K, Afreen E, Zaidi S, and Jumaa M

Abstract

Background and Objectives: Intracranial atherosclerotic disease (ICAD) large vessel occlusion (LVO) is responsible for up to 30% of LVO. In this study, we aimed to determine the likelihood of favorable functional outcomes (modified Rankin Scale 0-3) in acute ICAD-LVO basilar occlusion compared with embolic basilar occlusion., Methods: This is an analysis of the Posterior Circulation Ischemic Stroke Evaluation: Analyzing Radiographic and Intraprocedural Predictors for Mechanical Thrombectomy Registry in which patients with acute basilar artery occlusions from 8 comprehensive stroke centers were included from 2015 to 2021. Patients were dichotomized into with (ICAD-LVO) or without underlying ICAD (embolic). Descriptive statistics for each group and multivariate logistic analysis were performed on the primary outcome., Results: Three hundred forty-six patients were included. There were 215 patients with embolic (62%) and 131 patients with ICAD-LVO (38%). Baseline demographics were equivalent between the 2 groups except for sex (male 47% vs 67%; P < .001), history of stroke (12% vs 25%; P = .002), and atrial fibrillation (31% vs 17%; P = .003). At 90 days, patients in the ICAD-LVO cohort were less likely to achieve favorable functional outcomes (odds ratio [OR] 0.41, 95% CI 0.22-0.72; P = .003) after adjusting for potentially confounding factors. In addition, ICAD-LVO strokes were less likely to achieve thrombolysis in cerebral infarction ≥2b (OR 0.29, 95% CI 0.14-0.57; P < .001). ICAD-LVO lesions were more likely to require stent placement (OR 14.94, 95% CI 4.91-45.49; P < .001). Subgroup analysis demonstrated favorable functional outcomes in patients who underwent stenting and angioplasty compared with failed recanalization cohort (OR 4.96, 95% CI 1.68-14.64; P < .004)., Conclusion: Patients with acute basilar ICAD-LVO have higher morbidity and mortality compared with patients with embolic source. Lower rates of successful recanalization in the ICAD-LVO cohort support this finding. Our subgroup analysis demonstrates that stenting should be considered in patients with recanalization failure. Rates of symptomatic intracranial hemorrhage were similar between the ICAD-LVO and embolic cohorts., (Copyright © Congress of Neurological Surgeons 2024. All rights reserved.)

Published
2024
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28. Histology, Leydig Cells

Author

Aladamat N and Tadi P

Abstract

Leydig cells are essential and crucial cells located in the testes of the male gonads. They are known as testicular interstitial cells and can be found between seminiferous tubules, which contain Sertoli and germ cells. Together, these three cell types maintain spermatogenesis, control hormonal regulation, and affect secondary sexual characteristics in males. Leydig cells are under hormonal regulation by the hypothalamic-pituitary axis. These cells can be associated with some pathologic changes or cancerous malformation., (Copyright © 2022, StatPearls Publishing LLC.)

Published
2022

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