8 results on '"Alaa Al Ayoubi"'
Search Results
2. Craniofacial characteristics of Syrian adolescents with Class II division 1 malocclusion: a retrospective study
- Author
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Alaa Al Ayoubi, Daniel Dalla Torre, and Melinda Madléna
- Subjects
Dentofacial morphology ,Upper airway ,Tooth size ,Class II division 1 malocclusion ,Syrian adolescents ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background Malocclusion characteristics vary across different ethnic groups and populations. Limited data are available regarding the characteristics of Syrian adolescents with Class II division 1 (Class II-1) malocclusion, and the recent inflow of Syrian refugees and immigrants into Europe and many areas worldwide demonstrate the need for updated studies to discover the craniofacial characteristics of these new immigrants. Objectives The present compound cephalometric and tooth-size study sought to assess the dentofacial morphology, upper-airway dimensions, and tooth-size characteristics of Syrian adolescents with Class II-1 malocclusion and compare the results with established Syrian population norms. Materials and Methods The study sample consisted of 43 Syrian patients including 24 females and 19 males with Class II-1 malocclusion (age: 14.3 (±1.5) years, mean (±SD)). Cephalometric radiographs and orthodontic casts were analyzed using special orthodontic software (OnyxCeph3™) and a universal digital caliper, respectively. Statistics were calculated using the SPSS software. Results In Syrian adolescents with Class II-1 malocclusion, the position of the mandible relative to the nasion perpendicular (mean (95% confidence interval)) was −11.01 (−12.45, −9.57) mm. Facial axis angle showed a negative value: −6.25 (−7.65, −4.85) degrees. An obtuse nasolabial angle was observed: 104.05 (101.77, 106.33) degrees. The average width of the upper pharynx was 11.50 (10.53, 12.47) mm; however, there was no prevalence of an upper-pharyngeal width of 5 mm or less. The average value of the anterior tooth-size ratio was 80.69 (79.85, 81.53) percent. In total, 39.5% of the investigated subjects had anterior ratios outside two standard deviations from Bolton’s norm, while 25.6% of the investigated subjects had anterior ratios outside two standard deviations from Syrian population norm. Conclusions In this study, the inter-maxillary discrepancy of Class II-1 Syrian adolescents was a consequence of their hyperdivergent facial pattern. The observed small pharyngeal widths were not clinically significant, while the anterior tooth-size discrepancy might be clinically relevant.
- Published
- 2020
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3. Upper Airway Characteristics in Young Individuals With Class II Division 1 Malocclusion: A Retrospective Inter-Ethnic Cephalometric Comparison
- Author
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Alaa Al Ayoubi and Melinda Madléna
- Subjects
Adolescent ,Cephalometry ,Ethnic group ,Malocclusion, Angle Class II ,stomatognathic system ,medicine ,Humans ,Class II division 1 malocclusion ,Retrospective Studies ,Orthodontics ,Soft palate ,business.industry ,Pharynx ,Hyoid bone ,Hyoid Bone ,General Medicine ,medicine.disease ,Sagittal plane ,medicine.anatomical_structure ,Otorhinolaryngology ,Surgery ,Palate, Soft ,Malocclusion ,Airway ,business - Abstract
This study aimed to compare the upper-airway morphology between strictly matched Syrian (n = 43) and Hungarian (n = 43) adolescents with Class II/1 malocclusion and identify potential associations between upper airway depths and skeletofacial characteristics. Lateral cephalograms were analyzed, and independent-samples tests and correlation coefficients were used for the statistical analyses. The upper-pharyngeal airway was significantly narrower and the soft palate angle was significantly greater in the Syrian adolescents. Alternatively, the hyoid bone was more posteriorly positioned in the Hungarian adolescents when compared to their counterparts. Depths of the upper and middle pharynx were moderately correlated with sagittal and vertical skeletal dimensions only among Syrian subjects. The depth of the lower pharynx was moderately correlated with hyoid bone position, cervical length, and lip-chin-throat angle only among Hungarian subjects. These findings might have potential implications for optimizing the effects of orthognathic/orthodontic treatments on airway structures in these 2 groups.
- Published
- 2021
4. Dentoskeletal and tooth-size differences between Syrian and Hungarian adolescents with Class II division 1 malocclusion: a retrospective study
- Author
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Melinda Madléna, Alireza Khandan Dezfully, and Alaa Al Ayoubi
- Subjects
Male ,Adolescent ,Class II division 1 malocclusion ,lcsh:Medicine ,Malocclusion, Angle Class II ,General Biochemistry, Genetics and Molecular Biology ,Sex Factors ,Ethnic differences ,Humans ,Medicine ,TOOTH SIZE ,Child ,lcsh:Science (General) ,lcsh:QH301-705.5 ,Retrospective Studies ,Orthodontics ,Hungary ,Syria ,business.industry ,Tooth size ,lcsh:R ,Retrospective cohort study ,General Medicine ,medicine.disease ,humanities ,Research Note ,lcsh:Biology (General) ,Dentoskeletal structure ,Maxilla ,Female ,Malocclusion ,business ,lcsh:Q1-390 - Abstract
ObjectivesMalocclusion features differ across various populations and ethnicities. At this time, no data are available regarding the dentofacial differences between Syrian and European adolescents with Class II division 1 malocclusion, which is one of the most frequently treated pathologies in orthodontic practice. The present combined cephalometric and tooth-size study aimed to compare the dentoskeletal and tooth-size characteristics of Syrian and Hungarian adolescents with Class II division 1 malocclusion.ResultsClass II division 1 malocclusion in Hungarian adolescents was a sagittal discrepancy, while in Syrian adolescents, it was a result of excessive vertical development. Syrian adolescents had a significantly excessive vertical development when compared with Hungarian adolescents, regardless of sex(p 0.01). Hungarian boys had significantly more protruded maxillae(p 0.001)and less retruded mandibles (p 0.01)when compared with Syrian boys, while Hungarian girls had significantly shorter mandibles relative to those of Syrian girls (p 0.01). Syrian girls had significantly more protrusive lower incisors (p 0.001), accompanied by significantly larger anterior tooth-size ratios when compared to Hungarian girls (p 0.001). In conclusion, these findings underscore the importance of considering ethnic differences during orthodontic diagnosis and may have implications for optimizing orthodontic treatments in Syrian and Hungarian adolescents with Class II division 1 malocclusion.
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- 2020
5. Craniofacial Characteristics of Syrian and Hungarian Adolescents with Class II Division 1 Malocclusion
- Author
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Alaa Al Ayoubi
- Published
- 2021
6. Microbiomes in supragingival biofilms and saliva of adolescents with gingivitis and gingival health
- Author
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Mónika Klára Mester, Kornél L. Kovács, Melinda Madléna, Alaa Al Ayoubi, Janos Minarovits, Roland Wirth, Gergely Maróti, Lídia Lipták, and Bernadett Pap
- Subjects
Saliva ,03.03. Egészségtudományok ,Adolescent ,Dental Plaque ,medicine.disease_cause ,Microbiology ,03 medical and health sciences ,Gingivitis ,0302 clinical medicine ,RNA, Ribosomal, 16S ,medicine ,Humans ,03.02. Klinikai orvostan ,Microbiome ,General Dentistry ,biology ,Bacteria ,Campylobacter ,Microbiota ,Akkermansia ,030206 dentistry ,biology.organism_classification ,Otorhinolaryngology ,Fusobacterium ,Metagenomics ,030220 oncology & carcinogenesis ,Biofilms ,medicine.symptom ,Actinomyces - Abstract
Background Important alterations exist in the microbiomes of supragingival biofilm and saliva samples from adolescent patients developing induced or spontaneous gingivitis relative to healthy controls. These and the relationships to dental health are not fully understood yet. Subjects and methods Supragingival biofilm samples (n = 36) were collected from the teeth of 9 adolescents with gingivitis induced by orthodontic appliances, as well as dental plaques (n = 40) from 10 adolescents with spontaneous gingivitis, in addition to similar samples (n = 36) from 9 healthy controls. The bacterial metagenomes were analyzed by 16S rRNA gene amplicon sequencing. Salivary microbiomes of the same persons were characterized by shotgun metagenome sequencing. The data sets were examined using advanced bioinformatics workflows and two reference databases. Results The composition and diversity of bacterial communities did not differ extensively among the three study groups. Nevertheless, the relative abundances of the genera Fusobacterium, Akkermansia, Treponema, and Campylobacter were prominently higher in gingivitis patients versus controls. In contrast, the genera Lautropia, Kingella, Neisseria, Actinomyces, and Rothia were significantly more abundant in controls than in either of the two gingivitis groups. Conclusions The abundance pattern of certain taxa rather than individual strains shows characteristic features of potential diagnostic value. Stringent bioinformatics treatment of the sequencing data is mandatory to avoid unintentional misinterpretations.
- Published
- 2021
7. Author response for 'Microbiomes in supragingival biofilms and saliva of adolescents with gingivitis and gingival health'
- Author
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Kornél L. Kovács, Bernadett Pap, Alaa Al Ayoubi, Roland Wirth, Janos Minarovits, Lídia Lipták, Mónika Klára Mester, Melinda Madléna, and Gergely Maróti
- Subjects
Gingivitis ,Saliva ,business.industry ,Gingival health ,medicine ,Biofilm ,Dentistry ,Microbiome ,medicine.symptom ,business - Published
- 2020
8. Microbiomes in Supragingival Biofilms and Saliva of Adolescent Patients with Induced and Naturally Occurring Gingivitis Relative to Gingival Health
- Author
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Roland Wirth, Gergely Maróti, Lídia Lipták, Mónika Mester, Alaa Al Ayoubi, Bernadett Pap, Melinda Madléna, Janos Minarovits, and Kornél L. Kovács
- Abstract
Background: Comparison of the microbiomes in supragingival biofilm and saliva samples collected from juvenile patients developing induced or spontaneous gingivitis with healthy controls.Results: 36 supragingival biofilm samples from 9 adolescent gingivitis patients wearing orthodontic appliances (induced gingivitis), 40 supragingival plaques from 10 patients having spontaneous gingivitis, and 36 control samples from 9 individuals without gingivitis in the same age group were analyzed by 16S rRNA gene amplicon sequencing. Salivary microbiomes of the same persons were characterized by shotgun metagenome sequencing to compare the sessile, i.e. biofilm immobilized communities with planktonic microbiota. The amplicon and whole genome data sets were scrutinized using bioinformatics workflows designed to minimize systemic biases. RDP and RefSeq reference databases were compared in the identification of microbiome members.The composition and diversity of bacterial communities did not differ extensively between the two groups of gingivitis patients and controls. In spite of the overall similarities, the relative abundance of the genera Fusobacterium, Accermansia, Treponema and Campylobacter was prominently higher in samples from gingivitis patients versus controls. In contrast, the genera Lautropia, Kingella, Neisseria, Actinomyces and Rothia were significantly more abundant in controls than in either of the two gingivitis groups. Conclusions: The higher relative abundance of certain gingivitis-associated taxa may either reflect their role in disease pathogenesis or may indicate that gingival inflammation favored the selective overgrowth of distinct bacterial clusters. At any rate, the abundance pattern of certain taxa rather than individual strains shows characteristic features of potential diagnostic value. Stringent bioinformatics treatment of the sequencing data is mandatory to avoid unintentional misinterpretations.
- Published
- 2020
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