36 results on '"Al-Shamma, Hussien"'
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2. Anti-thrombotic and vascular effects of AR246686, a novel 5-HT 2A receptor antagonist
3. Anti-thrombotic and vascular effects of AR246686, a novel 5-HT2A receptor antagonist
4. The Selective Sphingosine 1-Phosphate Receptor Modulator Etrasimod Regulates Lymphocyte Trafficking and Alleviates Experimental Colitis
5. Discovery of 1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalen-4-carboxamides as potent and selective CB2 receptor agonists
6. Etrasimod (APD334), an Oral, Next‐Generation Sphingosine‐1‐Phosphate Receptor Modulator Inhibits the Development of Colitis in Lymphoid‐Null Mice Injected with Colitogenic CD4+ T Cells
7. Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists
8. Synthesis and in Vivo Evaluation of Phenethylpiperazine Amides: Selective 5-Hydroxytryptamine2AReceptor Antagonists for the Treatment of Insomnia
9. Fused tricyclic indoles as S1P1 agonists with robust efficacy in animal models of autoimmune disease
10. Identification of fused bicyclic heterocycles as potent and selective 5-HT2A receptor antagonists for the treatment of insomnia
11. Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P 1 agonists
12. (7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P1 Functional Antagonists
13. Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor
14. Diet‐Induced Models of Obesity (DIO) in Rodents
15. Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P1 agonists
16. Synthesis and in Vivo Evaluation of Phenethylpiperazine Amides: Selective 5-Hydroxytryptamine2A Receptor Antagonists for the Treatment of Insomnia
17. Discovery and Structure−Activity Relationship of 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): A Highly Selective 5-Hydroxytryptamine2A Receptor Inverse Agonist for the Treatment of Arterial Thrombosis
18. Discovery of 1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (Nelotanserin) and Related 5-Hydroxytryptamine2A Inverse Agonists for the Treatment of Insomnia
19. Nelotanserin, a Novel Selective Human 5-Hydroxytryptamine2A Inverse Agonist for the Treatment of Insomnia
20. APD791, 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide, a Novel 5-Hydroxytryptamine 2A Receptor Antagonist: Pharmacological Profile, Pharmacokinetics, Platelet Activity and Vascular Biology
21. Lorcaserin, a Novel Selective Human 5-Hydroxytryptamine2C Agonist: in Vitro and in Vivo Pharmacological Characterization
22. Neurogenesis of the sexually dimorphic vasopressin cells of the bed nucleus of the stria terminalis and amygdala of rats
23. Importance of target innervation in recovery from axotomy‐induced loss of androgen receptor in rat perineal motoneurons
24. The Sexually Dimorphic Vasopressin Innervation of the Brain as a Model for Steroid Modulation of Neuropeptide Transmission
25. Gonadal Steroid Modulation of Vasopressin Pathwaysa
26. Synthesis and in Vivo Evaluation of Phenethylpiperazine Amides: Selective 5-Hydroxytryptamine2A Receptor Antagonists for the Treatment of Insomnia.
27. Fiber outgrowth from fetal vasopressin neurons of the suprachiasmatic nucleus, bed nucleus of the stria terminalis, and medial amygdaloid nucleus transplanted into adult Brattleboro rats
28. Sex differences in hormonal responses of vasopressin pathways in the rat brain
29. The Sexually Dimorphic Vasopressin Innervation of the Brain as a Model for Steroid Modulation of Neuropeptide Transmissiona.
30. Nelotanserin, a novel selective human 5-hydroxytryptamine2A inverse agonist for the treatment of insomnia.
31. Identification of fused bicyclic heterocycles as potent and selective 5-HT2A receptor antagonists for the treatment of insomnia
32. Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P1 agonists
33. Anti-thrombotic and vascular effects of AR246686, a novel 5-HT2A receptor antagonist
34. Discovery and structure-activity relationship of 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): a highly selective 5-hydroxytryptamine2A receptor inverse agonist for the treatment of arterial thrombosis.
35. 5-HT(2A) inverse-agonists for the treatment of insomnia.
36. G protein-coupled receptors as therapeutic targets for obesity and type 2 diabetes.
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