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Reactions of 1,10‐phenanthroline (phen) and 2‐(3,4‐dichlorophenyl)acetic acid (dcaH) with Mn(CO3) (M = LiI, NaI and MgII; n = 1 and 2) in MeOH yield the mononuclear lithium complex aqua[2‐(3,4‐dichlorophenyl)acetato‐κO](1,10‐phenanthroline‐κ2N,N′)lithium(I), [Li(C8H5Cl2O2)(C12H8N2)(H2O)] or [Li(dca)(phen)(H2O)] (1), the dinuclear sodium complex di‐μ‐aqua‐bis{[2‐(3,4‐dichlorophenyl)acetato‐κO](1,10‐phenanthroline‐κ2N,N′)sodium(I)}, [Na2(C8H5Cl2O2)2(C12H8N2)2(H2O)2] or [Na2(dca)2(phen)2(H2O)2] (2), and the one‐dimensional chain magnesium complex catena‐poly[[[diaqua(1,10‐phenanthroline‐κ2N,N′)magnesium]‐μ‐2‐(3,4‐dichlorophenyl)acetato‐κ2O:O′] 2‐(3,4‐dichlorophenyl)acetate monohydrate], {[Mg(C8H5Cl2O2)(C12H8N2)(H2O)2](C8H5Cl2O2)·H2O}n or {[Mg(dca)(phen)(H2O)2](dca)·H2O}n (3). In these complexes, phen binds via an N,N′‐chelate pocket, while the deprotonated dca− ligands coordinate either in a monodentate (in 1 and 2) or bidentate (in 3) fashion. The remaining coordination sites around the metal ions are occupied by water molecules in all three complexes. Complex 1 crystallizes in the triclinic space group P with one molecule in the asymmetric unit. The Li+ ion adopts a four‐coordinated distorted seesaw geometry comprising an [N2O2] donor set. Complex 2 crystallizes in the triclinic space group P with half a molecule in the asymmetric unit, in which the Na+ ion adopts a five‐coordinated distorted spherical square‐pyramidal geometry, with an [N2O3] donor set. Complex 3 crystallizes in the orthorhombic space group P212121, with one Mg2+ ion, one phen ligand, two dca− ligands and three water molecules in the asymmetric unit. Both dcaH ligands are deprotonated, however, one dca− anion is not coordinated, whereas the second dca− anion coordinates in a bidentate fashion bridging two Mg2+ ions, resulting in a one‐dimensional chain structure for 3. The Mg2+ ion adopts a distorted octahedral geometry, with an [N2O4] donor set. Complexes 1–3 were evaluated against urease and α‐glucosidase enzymes for their inhibition potential and were found to be inactive. Reactions of 1,10‐phenanthroline (phen) and 2‐(3,4‐dichlorophenyl)acetic acid (dcaH) with Mn(CO3) (M = LiI, NaI and MgII; n = 1 and 2) in MeOH yield the mononuclear lithium complex, the dinuclear sodium complex and the one‐dimensional chain magnesium complex. In these complexes, phen binds via an N,N′‐chelate pocket, while the deprotonated dca− ligands coordinate either in a monodentate or bidentate fashion. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate antiglycation and antioxidant activities as undertake HPTLC analysis of Boswellia sacra resin. Methods: Sub-fractionation of the crude methanol extract of Hougari regular (HR) grade resin of Boswellia sacra was carried out by vacuum liquid chromatography. Free radical scavenging and antiglycation activities of sub-fractions were characterized in order to assess their anti-aging properties. Furthermore, high performance thin layer chromatography (HPTLC) analysis of Boswellia sacra resins was also carried out. Results: Polar fractions of the extract obtained exhibited the highest antiglycation activity while nonpolar fractions showed more than 50 % inhibition in superoxide anion scavenging assay. Scavenging activity of reactive oxygen species results indicate that non-polar sub-fractions showed > 50 % inhibition, except Shabi frankincense (SF) oil which showed 33 % inhibition. Dichloromethane (CH2Cl2) fraction, 40 % dichloromethane (CH2Cl2)/n-hexane sub-fraction, and SF oil showed moderate activity in di(phenyl)-(2,4,6-trinitrophenyl)iminoazanium (DPPH) assay. Furthermore, HPTLC analysis indicates the presence of 11-keto-ß-boswellic acid (KBA) and 3-O-acetyl-11-keto-ß-boswellic acid (AKBA) along with some other terpenoids. Conclusion: Various sub-fractions of Boswellia sacra exert effective antiglycation and antioxidant activities. The extracts should be studied further for possible formulation into pharmaceutical products. [ABSTRACT FROM AUTHOR]

Reactions of 1,10-phenanthroline (phen) and 2-(3,4-dichlorophenyl)acetic acid (dcaH) with M n (CO 3 ) (M = Li I , Na I and Mg II ; n = 1 and 2) in MeOH yield the mononuclear lithium complex aqua[2-(3,4-dichlorophenyl)acetato-κO](1,10-phenanthroline-κ 2 N,N')lithium(I), [Li(C 8 H 5 Cl 2 O 2 )(C 12 H 8 N 2 )(H 2 O)] or [Li(dca)(phen)(H 2 O)] (1), the dinuclear sodium complex di-μ-aqua-bis{[2-(3,4-dichlorophenyl)acetato-κO](1,10-phenanthroline-κ 2 N,N')sodium(I)}, [Na 2 (C 8 H 5 Cl 2 O 2 ) 2 (C 12 H 8 N 2 ) 2 (H 2 O) 2 ] or [Na 2 (dca) 2 (phen) 2 (H 2 O) 2 ] (2), and the one-dimensional chain magnesium complex catena-poly[[[diaqua(1,10-phenanthroline-κ 2 N,N')magnesium]-μ-2-(3,4-dichlorophenyl)acetato-κ 2 O:O'] 2-(3,4-dichlorophenyl)acetate monohydrate], {[Mg(C 8 H 5 Cl 2 O 2 )(C 12 H 8 N 2 )(H 2 O) 2 ](C 8 H 5 Cl 2 O 2 )·H 2 O} n or {[Mg(dca)(phen)(H 2 O) 2 ](dca)·H 2 O} n (3). In these complexes, phen binds via an N,N'-chelate pocket, while the deprotonated dca - ligands coordinate either in a monodentate (in 1 and 2) or bidentate (in 3) fashion. The remaining coordination sites around the metal ions are occupied by water molecules in all three complexes. Complex 1 crystallizes in the triclinic space group P-1 with one molecule in the asymmetric unit. The Li + ion adopts a four-coordinated distorted seesaw geometry comprising an [N 2 O 2 ] donor set. Complex 2 crystallizes in the triclinic space group P-1 with half a molecule in the asymmetric unit, in which the Na + ion adopts a five-coordinated distorted spherical square-pyramidal geometry, with an [N 2 O 3 ] donor set. Complex 3 crystallizes in the orthorhombic space group P2 1 2 1 2 1 , with one Mg 2+ ion, one phen ligand, two dca - ligands and three water molecules in the asymmetric unit. Both dcaH ligands are deprotonated, however, one dca - anion is not coordinated, whereas the second dca - anion coordinates in a bidentate fashion bridging two Mg 2+ ions, resulting in a one-dimensional chain structure for 3. The Mg 2+ ion adopts a distorted octahedral geometry, with an [N 2 O 4 ] donor set. Complexes 1-3 were evaluated against urease and α-glucosidase enzymes for their inhibition potential and were found to be inactive.