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379 results on '"Al-Amri, Abdullah"'

12. Advice on assistance and protection provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 3. On medical care and treatment of injuries from sulfur mustard

Author

Timperley, Christopher M., Forman, Jonathan E., Abdollahi, Mohammad, Al-Amri, Abdullah Saeed, Baulig, Augustin, Benachour, Djafer, Borrett, Veronica, Cariño, Flerida A., Curty, Christophe, Geist, Michael, Gonzalez, David, Kane, William, Kovarik, Zrinka, Martínez-Álvarez, Roberto, Mourão, Nicia Maria Fusaro, Neffe, Slawomir, Raza, Syed K., Rubaylo, Valentin, Suárez, Alejandra Graciela, Takeuchi, Koji, Tang, Cheng, Trifirò, Ferruccio, van Straten, Francois Mauritz, Vanninen, Paula S., Vučinić, Slavica, Zaitsev, Volodymyr, Zafar-Uz-Zaman, Muhammad, Zina, Mongia Saïd, Holen, Stian, Alwan, Wesam S., Suri, Vivek, Hotchkiss, Peter J., and Ghanei, Mostafa

Published
2021
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22. Seismic Hazard Assessment of Al Mashair Area, Makkah Al-Mukaramah (Saudi Arabia)

Author

Abdelrahman, Kamal, Al-Amri, Abdullah M., Al-Otaibi, Naif A., Fnais, Mohammad, Abdelmonem, Enayat, Pisello, Anna Laura, Editorial Board Member, Hawkes, Dean, Editorial Board Member, Bougdah, Hocine, Editorial Board Member, Rosso, Federica, Editorial Board Member, Abdalla, Hassan, Editorial Board Member, Boemi, Sofia-Natalia, Editorial Board Member, Mohareb, Nabil, Editorial Board Member, Mesbah Elkaffas, Saleh, Editorial Board Member, Bozonnet, Emmanuel, Editorial Board Member, Pignatta, Gloria, Editorial Board Member, Mahgoub, Yasser, Editorial Board Member, De Bonis, Luciano, Editorial Board Member, Kostopoulou, Stella, Editorial Board Member, Pradhan, Biswajeet, Editorial Board Member, Abdul Mannan, Md., Editorial Board Member, Alalouch, Chaham, Editorial Board Member, O. Gawad, Iman, Editorial Board Member, Amer, Mourad, Series Editor, Sundararajan, Narasimman, editor, Eshagh, Mehdi, editor, Saibi, Hakim, editor, Meghraoui, Mustapha, editor, Al-Garni, Mansour, editor, and Giroux, Bernard, editor

Published
2019
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24. Advice on assistance and protection provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 1. On medical care and treatment of injuries from nerve agents

Author

Timperley, Christopher M., Forman, Jonathan E., Abdollahi, Mohammad, Al-Amri, Abdullah Saeed, Baulig, Augustin, Benachour, Djafer, Borrett, Veronica, Cariño, Flerida A., Geist, Michael, Gonzalez, David, Kane, William, Kovarik, Zrinka, Martínez-Álvarez, Roberto, Mourão, Nicia Maria Fusaro, Neffe, Slawomir, Raza, Syed K., Rubaylo, Valentin, Suárez, Alejandra Graciela, Takeuchi, Koji, Tang, Cheng, Trifirò, Ferruccio, van Straten, Francois Mauritz, Vanninen, Paula S., Vučinić, Slavica, Zaitsev, Volodymyr, Zafar-Uz-Zaman, Muhammad, Zina, Mongia Saïd, and Holen, Stian

Published
2019
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26. Advice on assistance and protection by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 2. On preventing and treating health effects from acute, prolonged, and repeated nerve agent exposure, and the identification of medical countermeasures able to reduce or eliminate the longer term health effects of nerve agents

Author

Timperley, Christopher M., Abdollahi, Mohammad, Al-Amri, Abdullah Saeed, Baulig, Augustin, Benachour, Djafer, Borrett, Veronica, Cariño, Flerida A., Geist, Michael, Gonzalez, David, Kane, William, Kovarik, Zrinka, Martínez-Álvarez, Roberto, Fusaro Mourão, Nicia Maria, Neffe, Slawomir, Raza, Syed K., Rubaylo, Valentin, Suárez, Alejandra Graciela, Takeuchi, Koji, Tang, Cheng, Trifirò, Ferruccio, van Straten, Francois Mauritz, Vanninen, Paula S., Vučinić, Slavica, Zaitsev, Volodymyr, Zafar-Uz-Zaman, Muhammad, Zina, Mongia Saïd, Holen, Stian, Forman, Jonathan E., Alwan, Wesam S., and Suri, Vivek

Published
2019
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27. Geothermal and Volcanic Evaluation of Harrat Rahat, Northwestern Arabian Peninsula (Saudi Arabia)

Author

Al-Amri, Abdullah, Mellors, Robert, Harris, David, Camp, Vector, Abdelrahman, Kamal, Pisello, Anna Laura, Editorial Board Member, Hawkes, Dean, Editorial Board Member, Bougdah, Hocine, Editorial Board Member, Rosso, Federica, Editorial Board Member, Abdalla, Hassan, Editorial Board Member, Boemi, Sofia-Natalia, Editorial Board Member, Mohareb, Nabil, Editorial Board Member, Mesbah Elkaffas, Saleh, Editorial Board Member, Bozonnet, Emmanuel, Editorial Board Member, Pignatta, Gloria, Editorial Board Member, Mahgoub, Yasser, Editorial Board Member, De Bonis, Luciano, Editorial Board Member, Kostopoulou, Stella, Editorial Board Member, Pradhan, Biswajeet, Editorial Board Member, Abdul Mannan, Md., Editorial Board Member, Alalouch, Chaham, Editorial Board Member, O. Gawad, Iman, Editorial Board Member, Amer, Mourad, Series Editor, Doronzo, Domenico M., editor, Schingaro, Emanuela, editor, Armstrong-Altrin, John S., editor, and Zoheir, Basem, editor

Published
2019
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28. Advice on chemical weapons sample stability and storage provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons to increase investigative capabilities worldwide

Author

Timperley, Christopher M., Forman, Jonathan E., Abdollahi, Mohammad, Al-Amri, Abdullah Saeed, Alonso, Isel Pascual, Baulig, Augustin, Borrett, Veronica, Cariño, Flerida A., Curty, Christophe, Berrutti, David González, Kovarik, Zrinka, Martínez-Álvarez, Roberto, Mikulak, Robert, Mourão, Nicia Maria Fusaro, Ponnadurai, Ramasami, Neffe, Slawomir, Raza, Syed K., Rubaylo, Valentin, Takeuchi, Koji, Tang, Cheng, Trifirò, Ferruccio, van Straten, Francois Mauritz, Vanninen, Paula S., Zaitsev, Volodymyr, Waqar, Farhat, Zina, Mongia Saïd, Blum, Marc-Michael, Gregg, Hugh, Fischer, Elena, Sun, Siqing, and Yang, Pei

Published
2018
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36. Imaging ruptured lithosphere beneath the Red Sea and Arabian Peninsula

Author

Hansen, Samantha E., Rodgers, Arthur J., Schwartz, Susan Y., and Al-Amri, Abdullah M. S.

Subjects
Arabia, Red Sea, rifting, lithosphere-asthenosphere boundary, S-receiver functions
Abstract

The Red Sea Rift, an archetype of a newly formed ocean basin, is an ideal environment in which to study the controversial processes associated with continental rifting. Different models have been proposed to explain how rifting in the Red Sea evolved; however, accurate constraints on lithospheric structure have not been available to discriminate rifting models. We use the S-wave receiver function technique to produce the first images of the lithosphere-asthenosphere boundary (LAB) structure along the Red Sea and throughout the Arabian Peninsula. Lithospheric thickness varies considerably, with thin lithosphere centered on the rift axis, thickening toward the Arabian interior. Gravity data are well fit by our structural model and indicate that high surface topography along the rift flank is not in isostatic equilibrium, requiring dynamic compensation for its support. While our derived structure is consistent with active rifting processes, previous studies demonstrated that the Red Sea initiated as a passive rift. Therefore, our results suggest a two-stage rifting history, where extension and erosion by flow in the underlying asthenosphere are responsible for variations in LAB depth. LAB topography guides asthenospheric flow beneath western Arabia and the Red Sea, demonstrating the important role lithospheric variations play in the thermal modification of tectonic environments. (c) 2007 Elsevier B.V. All rights reserved.

Published
2007

46. Erratum to “Geochemical insights into the relationship of rock varnish and adjacent mineral dust fractions” [Chemical Geology 551 (2020) 119775]

Author

Otter, Laura M., primary, Macholdt, Dorothea S., additional, Jochum, Klaus Peter, additional, Stoll, Brigitte, additional, Weis, Ulrike, additional, Weber, Bettina, additional, Scholz, Denis, additional, Haug, Gerald H., additional, Al-Amri, Abdullah M., additional, and Andreae, Meinrat O., additional

Published
2022
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47. Springer Workshop on How to Get Published in a Scientific Journal: Tips from Springer Editors

Author

Khélifi, Nabil, Al-Amri, Abdullah, Abdalla, Hassan, Series editor, Abdul Mannan, Md., Series editor, Alalouch, Chaham, Series editor, Attia, Sahar, Series editor, Boemi, Sofia Natalia, Series editor, Bougdah, Hocine, Series editor, Bozonnet, Emmanuel, Series editor, De Bonis, Luciano, Series editor, Hawkes, Dean, Series editor, Kostopoulou, Stella, Series editor, Mahgoub, Yasser, Series editor, Mesbah Elkaffas, Saleh, Series editor, Mohareb, Nabil, Series editor, O. Gawad, Iman, Series editor, Oostra, Mieke, Series editor, Pignatta, Gloria, Series editor, Pisello, Anna Laura, Series editor, Rosso, Federica, Series editor, Kallel, Amjad, editor, Ksibi, Mohamed, editor, Ben Dhia, Hamed, editor, and Khélifi, Nabil, editor

Published
2018
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49. The Curcumin Analog PAC Is a Potential Solution for the Treatment of Triple-Negative Breast Cancer by Modulating the Gene Expression of DNA Repair Pathways.

Author

Almalki, Esraa, Al-Amri, Abdullah, Alrashed, Reem, AL-Zharani, Mohamed, and Semlali, Abdelhabib

Subjects
*BRCA genes, *TRIPLE-negative breast cancer, *DNA repair, *GENE expression, *CURCUMIN, *BREAST, *LUTEINIZING hormone releasing hormone
Abstract

Breast Cancer (BC) is one of the most common and challenging cancers among females worldwide. Conventional treatments for oral cancer rely on the use of radiology and surgery accompanied by chemotherapy. Chemotherapy presents many side effects, and the cells often develop resistance to this chemotherapy. It will be urgent to adopt alternative or complementary treatment strategies that are new and more effective without these negative effects to improve the well-being of patients. A substantial number of epidemiological and experimental studies reported that many compounds are derived from natural products such as curcumin and their analogs, which have a great deal of beneficial anti-BC activity by inducing apoptosis, inhibiting cell proliferation, migration, and metastasis, modulating cancer-related pathways, and sensitizing cells to radiotherapy and chemotherapy. In the present study, we investigated the effect of the curcumin-analog PAC on DNA repair pathways in MCF-7 and MDA-MB-231 human breast-cancer cell lines. These pathways are crucial for genome maintenance and cancer prevention. MCF-7 and MDA-MB-231 cells were exposed to PAC at 10 µM. MTT and LDH assays were conducted to evaluate the effects of PAC on cell proliferation and cytotoxicity. Apoptosis was assessed in breast cancer cell lines using flow cytometry with annexin/Pi assay. The expression of proapoptotic and antiapoptotic genes was determined by RT-PCR to see if PAC is active in programming cell death. Additionally, DNA repair signaling pathways were analyzed by PCR arrays focusing on genes being related and confirmed by quantitative PCR. PAC significantly inhibited breast-cancer cell proliferation in a time-dependent manner, more on MDA-MB-231 triple-negative breast cancer cells. The flow cytometry results showed an increase in apoptotic activity. These data have been established by the gene expression and indicate that PAC-induced apoptosis by an increased Bax and decreased Bcl-2 expression. Moreover, PAC affected multiple genes involved in the DNA repair pathways occurring in both cell lines (MCF-7 and MDA-MB231). In addition, our results suggest that PAC upregulated more than twice 16 genes (ERCC1, ERCC2, PNKP, POLL, MPG, NEIL2, NTHL1, SMUG1, RAD51D, RAD54L, RFC1, TOP3A, XRCC3, XRCC6BP1, FEN1, and TREX1) in MDA-MB-231, 6 genes (ERCC1, LIG1, PNKP, UNG, MPG, and RAD54L) in MCF-7, and 4 genes (ERCC1, PNKP, MPG, and RAD54L) in the two cell lines. In silico analysis of gene–gene interaction shows that there are common genes between MCF-7 and MDA-MB-321 having direct and indirect effects, among them via coexpression, genetic interactions, pathways, predicted and physical interactions, and shared protein domains with predicted associated genes indicating they are more likely to be functionally related. Our data show that PAC increases involvement of multiple genes in a DNA repair pathway, this certainly can open a new perspective in breast-cancer treatment. [ABSTRACT FROM AUTHOR]

Published
2023
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