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Your search keyword '"Al-Agha, Osama M."' showing total 19 results
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19 results on '"Al-Agha, Osama M."'

2. ARID1A mutations in endometriosis-associated ovarian carcinomas

Author

Wiegand, Kimberly C., Shah, Sohrab P., Al-Agha, Osama M., Yongjun Zhao, Tse, Kane, Zeng, Thomas, Senz, Janine, McConechy, Melissa K., Anglesio, Michael S., Kalloger, Steve E., Yang, Winnie, Heravi-Moussavi, Alireza, Guiliany, Ryan, Chow, Christine, Fee, John, Zayed, Abdalnasser, Prentice, Leah, Melnyk, Nataliya, Turashvili, Gulisa, Delaney, Allan D., Madore, Jason, Yip, Stephen, McPherson, Andrew W., Ha, Gavin, Bell, Lynda, Fereday, Sian, Tam, Angela, Galletta, Laura, Tonin, Patricia N., Provencher, Diane, Miller, Dianne, Jones, Steven J.M., Moore, Richard A., Morin, Gregg B., Oloumi, Arusha, Boyd, Niki, Aparicio, Samuel A., le_Ming Shih, Mes_Masson, Anne-Marie, Bowtell, David B., Hirst, Martin, Gilks, Blake, Marra, Marco A., and Huntsman, David

Subjects
Ovarian cancer -- Genetic aspects, Ovarian cancer -- Care and treatment, Gene mutations -- Research, Endometriosis -- Genetic aspects, Endometriosis -- Causes of, Tumor suppressor genes -- Research
Abstract

The study attempts to evaluate the data derived from the RNA sequencing of 18 ovarian carcinomas to identify variants in ARID1A mutations. The results indicate that ARIDIA mutations are present in ovarian carcinomas and that it is indicative of an early event in the transformation of endometriosis into cancer.

Published
2010

3. An in-depth look at Krukenberg tumor: an overview

Author

Al-Agha, Osama M. and Nicastri, Anthony D.

Subjects
Ovarian tumors -- Diagnosis, Ovarian tumors -- Analysis, Ovarian tumors -- Physiological aspects, Immunohistochemistry -- Usage
Published
2006

4. A 42-year-old woman with an abdominal mass

Author

Al-Agha, Osama M. and Tabassum, Farah

Subjects
Sarcoma -- Case studies, Sarcoma -- Diagnosis, Immunohistochemistry -- Evaluation, Abdominal cancer -- Case studies, Abdominal cancer -- Diagnosis
Published
2006

8. Pathology Quiz Case 2

Author

Al-Agha, Osama M., Guzman, Miguel A., and Lehto, Scott A.

Published
2007

10. ARID1AMutations in Endometriosis-Associated Ovarian Carcinomas

Author

Wiegand, Kimberly C., primary, Shah, Sohrab P., additional, Al-Agha, Osama M., additional, Zhao, Yongjun, additional, Tse, Kane, additional, Zeng, Thomas, additional, Senz, Janine, additional, McConechy, Melissa K., additional, Anglesio, Michael S., additional, Kalloger, Steve E., additional, Yang, Winnie, additional, Heravi-Moussavi, Alireza, additional, Giuliany, Ryan, additional, Chow, Christine, additional, Fee, John, additional, Zayed, Abdalnasser, additional, Prentice, Leah, additional, Melnyk, Nataliya, additional, Turashvili, Gulisa, additional, Delaney, Allen D., additional, Madore, Jason, additional, Yip, Stephen, additional, McPherson, Andrew W., additional, Ha, Gavin, additional, Bell, Lynda, additional, Fereday, Sian, additional, Tam, Angela, additional, Galletta, Laura, additional, Tonin, Patricia N., additional, Provencher, Diane, additional, Miller, Dianne, additional, Jones, Steven J.M., additional, Moore, Richard A., additional, Morin, Gregg B., additional, Oloumi, Arusha, additional, Boyd, Niki, additional, Aparicio, Samuel A., additional, Shih, Ie-Ming, additional, Mes-Masson, Anne-Marie, additional, Bowtell, David D., additional, Hirst, Martin, additional, Gilks, Blake, additional, Marra, Marco A., additional, and Huntsman, David G., additional

Published
2010
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16. An In-Depth Look at Leydig Cell Tumor of the Testis.

Author

Al-Agha, Osama M. and Axiotis, Constantine A.

Subjects
*TUMORS, *LEYDIG cells, *CELLULAR pathology, *DIAGNOSIS, *HISTOPATHOLOGY, *DIAGNOSTIC errors
Abstract

Leydig cell tumor (LCT) is a rare tumor of the male testicular interstitium. This article provides an overview of the major pathologic manifestations of LCT of the testis; patient characteristics; clinical, radiologic, and laboratory features; prognosis; and management. LCTs of the testis are frequently hormonally active, leading to either feminizing or virilizing syndromes. The tumor is usually benign, but malignant variants can occur. The pathologic diagnosis of LCT is usually made based on morphologic characteristics of the tumor cells. The significance of Reinke crystals in the diagnosis of LCT both cytologically and histologically is underscored. Pathologists have to be familiar with the diagnostic histopathologic features, immunohistochemical panel of this tumor, and its principal differential diagnoses to prevent tumor misdiagnosis. [ABSTRACT FROM AUTHOR]

Published
2007
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17. CD138 (Syndecan-1) in thymic tumors: correlation with various World Health Organization types and clinical outcome.

Author

Al-Agha OM, Liu W, Chandrasekhar R, Wilding G, Tan D, Alrawi S, and Khoury T

Subjects
Adult, Aged, Aged, 80 and over, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Neoplasm Staging, Prognosis, Retrospective Studies, Thymus Gland metabolism, Thymus Gland pathology, Thymus Neoplasms diagnosis, Syndecan-1 metabolism, Thymus Neoplasms classification, Thymus Neoplasms metabolism, World Health Organization
Abstract

We intended to explore the relationship of CD138 with thymic tumors. A series of 64 thymic tumors were studied. Positive staining was seen in 7 of 8 (87.5%) type A, 7 of 16 (43.7%) type AB, 1 of 8 (12.5%) type B1, 1 of 5 (20%) type B2, 10 of 17 (58.8%) type B3, and 3 of 10 (30%) type C (p=0.04), respectively. In terms of subcellular location of CD138 expression, 9 of 10 (90%) CD138 positive type B3 had membranous expression, while cytoplasmic expression was identified in 7 of 7 (100%) type A, and 6 of 7 (86%) type AB (p<0.0001). Positive CD138 was noted in 20 of 31 (64.5%) cases with Masaoka stage I (p= 0.01); while negative CD138 was seen in 24 of 33 (72.7%) cases with Masaoka stages (II-IV). Tumor recurred in 4 cases (7%), all of which had negative CD138 (p=0.008). Our study suggests that CD138 could be used as an ancillary study to differentiate between WHO types. Furthermore, our findings demonstrate that advanced stage-thymic tumors as well as those with high recurrence rate tend to display a reduced expression of CD138. However, more studies with larger cohort and longer follow-up are warranted to validate the clinical utility of CD138 to assess clinical behavior and prognosis of thymic tumors.

Published
2010

18. Check Sample Abstracts.

Author

Alter D, Grenache DG, Bosler DS, Karcher RE, Nichols J, Rajadhyaksha A, Camelo-Piragua S, Rauch C, Huddleston BJ, Frank EL, Sluss PM, Lewandrowski K, Eichhorn JH, Hall JE, Rahman SS, McPherson RA, Kiechle FL, Hammett-Stabler C, Pierce KA, Kloehn EA, Thomas PA, Walts AE, Madan R, Schlesinger K, Nawgiri R, Bhutani M, Kanber Y, Abati A, Atkins KA, Farrar R, Gopez EV, Jhala D, Griffin S, Jhala K, Jhala N, Bentz JS, Emerson L, Chadwick BE, Barroeta JE, Baloch ZW, Collins BT, Middleton OL, Davis GG, Haden-Pinneri K, Chu AY, Keylock JB, Ramoso R, Thoene CA, Stewart D, Pierce A, Barry M, Aljinovic N, Gardner DL, Barry M, Shields LB, Arnold J, Stewart D, Martin EL, Rakow RJ, Paddock C, Zaki SR, Prahlow JA, Stewart D, Shields LB, Rolf CM, Falzon AL, Hudacki R, Mazzella FM, Bethel M, Zarrin-Khameh N, Gresik MV, Gill R, Karlon W, Etzell J, Deftos M, Karlon WJ, Etzell JE, Wang E, Lu CM, Manion E, Rosenthal N, Wang E, Lu CM, Tang P, Petric M, Schade AE, Hall GS, Oethinger M, Hall G, Picton AR, Hoang L, Imperial MR, Kibsey P, Waites K, Duffy L, Hall GS, Salangsang JA, Bravo LT, Oethinger MD, Veras E, Silva E, Vicens J, Silva E, Keylock J, Hempel J, Rushing E, Posligua LE, Deavers MT, Nash JW, Basturk O, Perle MA, Greco A, Lee P, Maru D, Weydert JA, Stevens TM, Brownlee NA, Kemper AE, Williams HJ, Oliverio BJ, Al-Agha OM, Eskue KL, Newlands SD, Eltorky MA, Puri PK, Royer MC, Rush WL, Tavora F, Galvin JR, Franks TJ, Carter JE, Kahn AG, Lozada Muñoz LR, Houghton D, Land KJ, Nester T, Gildea J, Lefkowitz J, Lacount RA, Thompson HW, Refaai MA, Quillen K, Lopez AO, Goldfinger D, Muram T, and Thompson H

Abstract

The following abstracts are compiled from Check Sample exercises published in 2008. These peer-reviewed case studies assist laboratory professionals with continuing medical education and are developed in the areas of clinical chemistry, cytopathology, forensic pathology, hematology, microbiology, surgical pathology, and transfusion medicine. Abstracts for all exercises published in the program will appear annually in AJCP.

Published
2009
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