91 results on '"Al Alawi M"'
Search Results
2. Prevalence and correlates of depressive symptoms among medical students: A cross-sectional single-centre study
- Author
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Al-Maashani, M, Al-Balushi, N, Al-Alawi, M, Mirza, H, Al-Huseini, S, Al-Balushi, M, Obeid, Y, Jose, S, Al-Sibani, N, and Al-Adawi, S
- Published
- 2020
3. International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module
- Author
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Desse, J.E., Maurizi, D.M., Montanini, A.M., Chaparro, G.J., Stagnaro, J.P., Romani, A., Bianchi, A.C., Álvarez, G., Palaoro, A., Bernan, M., Cabrera-Montesino, R., Domínguez, C., Rodríguez, C.G., Silva, C.G., Bogdanowicz, E., Riera, F.O., Benchetrit, G., Perez, I., Vimercati, J., Marcos, L.S., Ramasco, L., Caridi, M., Oyola, M.C., Rodríguez, M.C., Spadaro, M.L., Olivieri, M.S., Saul, P., Juarez, P.D., Pérez, R.H., Botta, P., Quintana, D.Q., Ríos, A.M., Chediack, V., Chilon, W., Alsayegh, Ameena Isa, Yaseen, Fatema Hasan, Hani, Lateefa Fardan, Sowar, Saleh Fakher, Magray, Tahira Anwar, Medeiros, E.A., Alves De Oliveira, A., Romario-Mendes, A., Fernandes-Valente, C., Santos, C., Escudeiro, D., Azevedo-Ferreira Lima, D., Azevedo-Pereira, D., Onzi-Siliprandi, E.M., Serpa-Maia, F., Aguiar-Leitao, F., Assuncao-Ponte, G., Dos Anjos-Lima, J., Olszewski, J., Harten Pinto Coelho, K., Alves De Lima, L.F., Mendonca, M., Maciel-Canuto Amaral, M.L., Tenorio, M.T., Gerah, S., Andrade-Oliveira-Reis, M., Moreira, M., Ximenes-Rocha Batista, M., Campos-Uchoa, R.S., Rocha-Vasconcelos Carneiro, R., Amaral De Moraes, R., Do Nascimento, S.C., Moreira-Matos, T., Lima-De Barros Araujo, T.M., De Jesus Pinheiro-Bandeira, T., Machado-Silva, V.L., Santos Monteiro, W.M., Hristozova, E., Kostadinov, E.D., Angelova, K., Velinova, V.A., Dicheva, V.J., Guo, X., Ye, G., Li, R., Song, L., Liu, K., Liu, T., Song, G., Wang, C., Yang, X., Yu, H., Yang, Y., Martínez, A., Vargas-García, A.R., Lagares-Guzmán, A., González, A.P., Linares, C., Ávila-Acosta, C., Santofimio, D., Yepes-Gomez, D., Marin-Tobar, D.A., Mazo-Elorza, D.P., Chapeta-Parada, E.G., Camacho-Moreno, G., Roncancio-Vill, G.E., Valderrama-Marquez, I.A., Ruiz-Gallardo, J.E., Ospina-Martínez, J.O., Osorio, J., Marín-Uribe, J.I., López, J.C., Gualtero, S., Rojas, J.R., Gomez-Nieto, K., Rincon, L.Y.M., Meneses-Ovallos, L., Canas-Giraldo, L.M., Burgos-Florez, L.D., Amaral-Almeida Costa, M., Rodriguez, M., Barahona-Guzmán, N., Mancera-Paez, O., Rios-Arana, P.A., Ortega, R., Romero-Torres, S.L., Pulido-Leon, S.M., Valderrama, S., Moreno-Mejia, V.M., Raigoza-Martinez, W., Villamil-Gomez, W., Pardo-Lopez, Y.A., Argüello-Ruiz, A., Solano-Chinchilla, A., Muñoz-Gutierrez, G.A., Calvo-Hernández, I., Maroto-Vargas, L., Zuniga, M.A., Valverde-Hernandez, M., Chavarria-Ugalde, O., Herrera, B., Díaz, C., Bovera, M.M., Cevallos, C., Pelaez, C., Jara, E., Delgado, V., Coello-Gordon, E.E., Picoita, F., Guerrero-Toapant, F.M., Valencia, F., Santacruz, G., Gonzalez, H., Pazmino, L.N., Garcia, M.F., Arboleda, M., Lascano, M., Alquinga, N., Ramírez, V., Yousef, Reham H.A., Moustafa, Abd El Moniem, Ahmed, A., Elansary, A.M., Ali, Ahmad Mahmoud, Hasanin, Ahmed, Messih, Antoine Abdel, Ramadan, Arwa, El Awady, B.A., Hassan, D.M., Abd El Aziz, Doaa, Hamza, Hala, Agha, Hala Mounir, Ghazi, Islam Abdullorziz, ElKholy, J., Fattah, May Abdel, Elanany, Mervat, Mansour, M., Haleim, M.M.A., Fouda, R., El-Sherif, Rasha Hamed, Bekeit, S., Bayani, V., Elkholy, Y.S., Abdelhamid, Y.M., Salah, Zeinab, Rivera, D.M., Chawla, A., Manked, A.N., Azim, A., Mubarak, A., Thakur, A., Dharan, A.V., Patil, A., Sasidharan, A., Bilolikar, Anil Kumar, Anirban Karmakar, A., Mathew, A.M., Kulkarni, Anuja, Agarwal, Anuradha, Sriram, Anuradha, Dwivedy, A., Dasgupta, Arnab, Bhakta, A., Suganya, Arul Rose, Poojary, A., Mani, Ashwin Kumar, Sakle, Asmita, Abraham, Babu K., Padmini, Baby, Ramachandran, B., Ray, Banambar, Pati, Basanta Kumar, Chaudhury, Bhaskar Narayan, Mishra, Biraj Mohan, Biswas, S., Saibala, M. Bri, Jawadwala, Burhan Q., Rodrigues, C., Modi, Chirag, Patel, Chirag, Khanna, D.K., Devaprasad, Dedeepiya, Divekar, Deepa, Aggarwal, Deepesh G., Divatia, J.V., Zala, Dolatsinh, Pathrose, Edwin, Abubakar, Fazil, Chacko, Felcy, Gehlot, G.S., Khanna, Gautam, Sale, H.K., Roy, Indranil, Shelgaonkar, Jayant, Sorabjee, Jehangir, Eappen, Jincy, Mathew, Justin, Pal, Jyotishka, Varma, Karthikeya, Joshi, Kashmira Limaye, Sandhu, Kavita, Kelkar, R., Ranganathan, Lakshmi, Pushparaj, L., Lavate, Madhav, Latha, Madhavi, Suryawanshi, Madhupriya, Bhattacharyya, M., Kavathekar, Maithili, Agarwal, Manoj Kumar, Patel, Mayur, Shah, Mehul, Sivakumar, M.N., Kharbanda, Mohit, Bej, Mrinmoy, Potdar, Mrunalini, Chakravarthy, M., Karpagam, M., Myatra, S.N., Gita, N., Rao, N.P., Sen, N., Ramakrishnan, N., Jaggi, N., Saini, N., Pawar, N.K., Modi, Nikhil, Pandya, Nirav, Mohanty, Nisith, Thakkar, Pooja, Joshi, Pradnya, Sahoo, Prafulla Kumar, Nair, Pravin Kumar, Kumar, Priyadarshini Senthil, Patil, Priyanka, Mukherjee, Purnima, Mathur, P., Shah, Purvi, Sukanya, R., Arjun, Rajalakshmi, Chawla, Rajesh, Gopalakrishnan, Ram, Venkataraman, Ramesh, Raut, S., Krupanandan, Ravikumar, Tejam, Reshma, Misra, Richa, Debroy, Ritesh, Saranya, S., Narayanan, Sajith, Mishra, Sanghamitra, Saseedharan, Sanjith, Sengupta, Sankar, Patnaik, S.K., Sinha, Saswati, Blessymole, Seelas, Rohra, Seema, Rajagopal, Senthilkumar, Mukherjee, Shanta, Sengupta, Sharmila, John, Sheeba, Bhattacharya, Shefali, Sijo, Bhattacharyya, Sinchan, Singh, S., Sohanlal, T., Vadi, Sonali, Dalal, S.S., Todi, S.K., Kumar, Subodh, Kansal, Sudha, Misra, Sudhjan, Bhattacharyya, Sudipta, Nirkhiwale, Suhas, Purkayastha, Sujit Kar, Mukherjee, Sujoy, Sahu, S., Sharma, Sunil, Kumar, Suresh, Basu, S., Shetty, S., Shah, S., Singhal, T., Francis, Thara, Anand, Thejasvini, Venkateshwar, V., Thomas, Valsa, Kothari, V., Velupandi, Kantroo, Vini, Sitohang, Gortap, Kadarsih, Retno, Sanaei, Anahita, Maghsudi, Behzad, Sabetian, Golnar, Masjedi, Mansoor, Alebouyeh, Masoud, Sherafat, Somayeh Jahani, Mohamed, Yassir Khidir, Al Khamis, Abdulrahim, Alsaadi, Adnan Soliman, Al-Jarie, Ahmed Abdoh, Mutwalli, Aisha Hassan, Rillorta, A.S.K., Thomas, Anumol, Kelany, Ashraf, Manao, Athena, Alamri, Dhaffer Moghram, Santiago, E.B., Cruzpero, E.P., Sawan, Fahad Ahmed, Al Qasmah, Fatima Abdullah, Alabdaly, Haeel, Al-Dossary, Hajer Am, Ahmed, Hala, Roshdi, Hala, Al-Alkami, Halima Yahia, Hanafi, Hana, Ammari, Hassan Eisa, Hani, Hatem Mohd Al, Asiri, Ibrahim A.M. Alzaydani, Mendoza, Jeffrey Asidera, Philipose, Jomol, Selga, Joy Ola, Kehkashan, Ghalilah, Khalid Mohammed, Redito, Leide Shyrine, Josph, L., Al-Alawi, M., Al-Gethamy, Manal Mansour, Madco, Marjory, Manuel, M.G., Girvan, M., Aldalaton, Mervat, De Guzman, M., Alkhamaly, Modhi, Masfar, Mohammad, Karrar, Mohammed Ahmed Ali, Al Azmi, Munayfa Musallam, Quisai, Myrna Lim, Torres, Myrna Misador, Al-Abdullah, N., Tawfic, Nader Ahmed, Elsayed, Nashwa, Abdulkhalik, Nawal Salah, Bugis, Nehad Abdulshakour, Ariola, Neilia Cardinal, Gad, N., Alghosn, Nesreen, Tashkandi, Nidal, Zharani, N. Al, De Vera, P.A., Krishnan, Radhika, Al Shehri, Raed Hassan, Jaha, Rasha Nour Aldeen, Thomas, Reny, Cresencia, Rhea Lynn, Penuliar, R., Lozada, R.V., Al Qahtani, S., Twfik, Sameh, Al Faraj, Sarah Hassan, El-Sherbiny, Sherin, Alih, Siti Jhulmina B., Briones, Solita, Bukhari, Syed Zahid, Alotaibi, Tariq Saad Abdulhadi, Gopal, Uma, Nair, Usha, Abdulatif, Wael Abdulrahman, Hussain, Waleed Mohd, Demotica, Wynndale Mae, Spahija, G., Baftiu, N., Gashi, A., Omar, Abeer A., Mohamed, A.M., Rebello, F.M., Almousa, Haifaa Hassan, Abdo, Naglaa Mahmoud, George, S.M., Khamis, Soad, Thomas, Suja, Ahmad Zaatari, A., Anwar Al Souheil, A., Ayash, H., Zeid, I., Tannous, J., Zahreddine, N.K., Ahmadieh, R., Mahfouz, T., Kardas, T., Tanzi, V., Kanafani, Z., Hammoud, Z., Dagys, A., Grinkeviciute, D., Kevalas, R., Kondratas, T., Petrovska, Milena, Popovska, Katja, Mitrev, Zan, Miteva, Zaneta Bogoevska, Jankovska, Katerina, Guroska, Snezana Tufekcievska, Gan, Chin Seng, Othman, Ainul Auzani, Yusof, Aliza Mohamad, Abidin, Anis Siham Zainal, Aziz, Fadzlina Abdul, Weng, Foong Kit, Zainol, Hasimah, Bakar, Kamal Bashar Abu, Lum, Lucy Chai See, Mansor, Marzida, Zaman, Mazuin Kamarul, Jamaluddin, Mohamad Fadhil Hadi, Hasan, Mohd Shahnaz, Rahman, Raha Abdul, Zaini, Rhendra Hardy Mohamad, Zhazali, Rosliza, Sri Ponnampala, Sasheela Sri La, Chuah, Soo Lin, Shukeri, Wan Fadzlina Wan Mohd, Hassan, Wan Nazaruddin Wan, Yusoff, Wan Nurbayah Wan, Mat, Wan Rahiza Wan, Cureno-Diaz, M.A., Aguirre-Avalos, G., Flores-Alvarado, A., Cerero-Gudino, A., Zamores-Pedroza, A., Cano-Munoz, B., Hernandez-Chena, B.E., Carreon-Martinez, C.C., Coronado-Magana, H., Corona-Jimenez, F., Rodriguez-Noriega, E., Alcala-Martinez, E., Gonzalez-Diaz, E., Guerra-Infante, F.M., Arteaga-Troncoso, G., Martinez-Falcon, G., Leon-Garnica, G., Delgado-Aguirre, H.A., Perez-Gomez, H.R., Sosa-Gonzalez, I.E., Galindo-Olmeda, J.A., Ayala-Gaytan, J.J., Rodriguez-Pacheco, J., Zamorano-Flores, L., Lopez-Pulgarin, J.A., Miranda-Novales, M.G., Ramírez, M., Lopez-Hurtado, M., Lozano, M., Gomez, M.E., Sanchez-Castuera, M.E., Kasten-Monges, M., Gonzalez-Martinez, M., Sanchez-Vargas, M., Culebro-Burguet, M.C., Altuzar-Figueroa, M.A., Mijangos-Mendez, J.C., Ramires, O.G., Espinosa, O.S., De Leon-Escobedo, R., Salas-Flores, R., Ruiz-Rendon, R., Petersen-Morfin, S., Aguirre-Diaz, S.A., Esparza-Ahumada, S., Vega-Gonzalez, S., Gaona-Flores, V., Monroy-Colin, V.A., Cruz-Rivera, Z., Bat-Erdene, A., Narankhuu, Batsaikhan, Choijamts, Batsuren, Tuvdennyam, Battsetseg, Batkhuu, Byambadorj, Chuluunchimeg, K.H., Enkhtsetseg, D., Batjargal, G., Bayasgalan, G., Dorj, M., Mendsaikhan, Naranpurev, Baatar, Otgon, Suvderdene, P., Baigalmaa, S., Khajidmaa, T., Begzjav, Tsolmon, Tsuyanga, Ariyasuren, Z., Zeggwagh, A.A., Berechid, K., Abidi, K., Madani, N., Abouqal, R., Koirala, Anjeela, Giri, Rashmi, Sainju, Samana, Acharya, Subhash Prasad, Ahmed, Abeera, Raza, Aun, Parveen, Azra, Sultan, Faisal, Khan, Maria, Paul, Nadeem, Daud, Nargis, Yusuf, Sana, Nizamuddin, Summiya, Garcia-Mayorca, E., Castaño, E.G., Moreno-Castillo, J.L., Ballinas-Aquino, J.M., Lara, L., Vargas, M., Rojas-Bonilla, M.I., Ramos, S.J., Mapp, T., De Iturrado, V., La Hoz Vergara, C.E., Linares-Calderon, C.F., Moreno, D., Ramirez, E., Ramírez Wong, F.M., Montenegro-Orrego, G.M., Sandoval-Castillo, H.R., Pichilingue-Chagray, J., Mueras-Quevedo, J., Aibar-Yaranga, K.F., Castillo-Bravo, L.I., Santivanez-Monge, L.M., Mayorga-Espichan, M.J., Rosario-Tueros, M.L.G., Changano-Rodriguez, M.V., Salazar-Ramirez, N.E., Marquez-Mondalgo, V.A., Tajanlangit, Anna Lyn N., Tamayo, Arnefelina S., Llames, Cristina Mari Jean P., Labro, Ever, Dy, Ana P., Fortin, J.D., Bergosa, L.D., Salvio, L.G., Bermudez, V., Sg-Buenaflor, M.C., Trajano, M.F., Mendoza, M.T., Javellana, O.P., Maglente, R.R., Arreza-Galapia, Y., Navoa-Ng, J.A., Kubler, A., Barteczko-Grajek, B., Dragan, B., Zurawska, M., Mikaszewska-Sokolewicz, M., Zielinska, M., Ramos-Ortiz, G.Y., Florin-Rogobete, A., Vlad, C. Daliborca, Muntean, D., Sandesc, D., Papurica, M., Licker, M., Bedreag, Ovidiu Horea, Popescu, R., Grecu, S.D., Dumitrascu, V., Molkov, A., Galishevskiy, D., Furman, M., Simic, A., Lekic, D., Ristic, G., Eremija, J., Kojovic, J., Nikolic, L., Bjelovic, M., Lesnakova, A., Hlinkova, S., Gamar-Elanbya, M.O., Supa, Namphon, Prasan, Pornpheth, Pimathai, Rungratchanee, Wanitanukool, Suthinee, Somabutr, Suwara, Ben-Jaballah, N., Borgi, A., Bouziri, A., Dilek, A., Oncul, A., Kaya, A., Demiroz, Ali Pekcan, Gunduz, A., Ozgultekin, A., Inan, Asuman, Yalcin, A.N., Ramazanoglu, A., Engin, A., Willke, A., Meco, Basak Ceyda, Aygun, C., Bulut, C., Uzun, C., Becerik, C., Hatipoglu, Cigdem Ataman, Guclu, Cigdem Yildirim, Ozdemir, D., Yildizdas, D., Ugurcan, D., Azak, E., Guclu, E., Yilmaz, Esmeray Mutlu, Sebnem-Erdinc, F., Sirmatel, F., Ulger, F., Sari, Ferhat, Kizilates, Filiz, Usluer, G., Ceylan, G., Ersoz, G., Kaya, G., Ertem, Gunay Tuncer, Senol, G., Agin, Hasan, Cabadak, Hatice, Yilmaz, H., Sungurtekin, Hulya, Zengin, Humeyra, Turgut, H., Ozgunes, I., Devrim, I., Erdem, I., Işcanlı, Inşa Gul Ekiz, Bakir, M. Mehmet, Geyik, M.F., Oral, M., Meric, M., Cengiz, M., Ozcelik, M., Altindis, M., Sunbul, M., Elaldi, N., Kuyucu, N., Unal, N., Oztoprak, N., Yasar, N., Erben, Nurettin, Bayram, Nuri, Dursun, Oguz, Karabay, Oguz, Coskun, O., Horoz, Ozden Ozgur, Turhan, Ozge, Sandal, Ozlem Sarac, Tekin, Recep, Esen, Saban, Erdogan, Selvi Yener, Unal, Serhat, Karacorlu, Sevim, Sen, Suha, Sacar, Suzan, Yarar, Volkan, Oruc, Yeliz, Sahip, Yusuf, Kaya, Zeynep, Philip, Anamma, Elhoufi, Ashraf, Alrahma, Hussain, Sachez, E., Perez, F., Empaire, G.D., Vidal, H., Montes-Bravo, L., Guzman Siritt, M.E., Orozco, N., Navarrete, N., Ruiz, Y., De Anez, Z. Duran-Gil, Van Trang, Dang Thi, Minh, Dao Quang, Co, Dao Xuan, Anh, Dinh Pham Phuong, Thu, Le Thi Anh, Tuyet, Le Thi Diem, Nguyet, Le Thi Thu, Chau, Ngo uy, Binh, Nguyen Gia, Tien, Nguyen Phuc, Anh, Nguyen Quoc, Hang, Phan Thi, Hanh, Tran Thi My, Hang, Tran Thi Thuy, Thu, Truong Anh, Thoa, Vo Thi Hong, Rosenthal, Víctor Daniel, Al-Abdely, Hail M., El-Kholy, Amani Ali, AlKhawaja, Safa A Aziz, Leblebicioglu, Hakan, Mehta, Yatin, Rai, Vineya, Hung, Nguyen Viet, Kanj, Souha Sami, Salama, Mona Foda, Salgado-Yepez, Estuardo, Elahi, Naheed, Morfin Otero, Rayo, Apisarnthanarak, Anucha, De Carvalho, Braulio Matias, Ider, Bat Erdene, Fisher, Dale, Buenaflor, Maria Carmen S.G., Petrov, Michael M., Quesada-Mora, Ana Marcela, Zand, Farid, Gurskis, Vaidotas, Anguseva, Tanja, Ikram, Aamer, Aguilar de Moros, Daisy, Duszynska, Wieslawa, Mejia, Nepomuceno, Horhat, Florin George, Belskiy, Vladislav, Mioljevic, Vesna, Di Silvestre, Gabriela, Furova, Katarina, Ramos-Ortiz, Gloria Y., Gamar Elanbya, May Osman, Satari, Hindra Irawan, Gupta, Umesh, Dendane, Tarek, Raka, Lul, Guanche-Garcell, Humberto, Hu, Bijie, Padgett, Denis, Jayatilleke, Kushlani, Ben Jaballah, Najla, Apostolopoulou, Eleni, Prudencio Leon, Walter Enrique, Sepulveda-Chavez, Alejandra, Telechea, Hector Miguel, Trotter, Andrew, Alvarez-Moreno, Carlos, and Kushner-Davalos, Luis
- Published
- 2016
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4. Alpha-1 proteinase inhibitors for the treatment of alpha-1 antitrypsin deficiency: safety, tolerability, and patient outcomes
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Chotirmall SH, Al-Alawi M, McEnery T, and McElvaney NG
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Therapeutics. Pharmacology ,RM1-950 - Abstract
Sanjay H Chotirmall,1 Mazen Al-Alawi,2 Thomas McEnery,2 Noel G McElvaney2 1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; 2Department of Respiratory Medicine, Beaumont Hospital, Dublin, Republic of Ireland Abstract: Alpha-1 antitrypsin (AAT) deficiency remains an underrecognized genetic disease with predominantly pulmonary and hepatic manifestations. AAT is derived primarily from hepatocytes; however, macrophages and neutrophils are secondary sources. As the natural physiological inhibitor of several proteases, most importantly neutrophil elastase (NE), it plays a key role in maintaining pulmonary protease–antiprotease balance. In deficient states, unrestrained NE activity promotes damage to the lung matrix, causing structural defects and impairing host defenses. The commonest form of AAT deficiency results in a mutated Z AAT that is abnormally folded, polymerized, and aggregated in the liver. Consequently, systemic levels are lower, resulting in diminished pulmonary concentrations. Hepatic disease occurs due to liver aggregation of the protein, while lung destruction ensues from unopposed protease-mediated damage. In this review, we will discuss AAT deficiency, its clinical manifestations, and augmentation therapy. We will address the safety and tolerability profiles of AAT replacement in the context of patient outcomes and cost-effectiveness and outline future directions for work in this field. Keywords: alpha-1, augmentation, deficiency, replacement, emphysema
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- 2015
5. Evaluation of the efficacy of transcricoid lignocaine as adjunctive local anaesthesia for fiberoptic bronchoscopy
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Hamad, S., Al-Alawi, M., Devaney, N., Subramaniam, A., and Lane, S.
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- 2015
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6. A study into efficacy of omalizumab therapy in patients with severe persistent allergic asthma at a tertiary referral centre for asthma in Ireland
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Subramaniam, A., Al-Alawi, M., Hamad, S., O’Callaghan, J., and Lane, S.J.
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- 2013
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7. Eosinophil peroxidase induces the expression and function of acid-sensing ion channel-3 in allergic rhinitis: in vitro evidence in cultured epithelial cells
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Khoo, S. G., Al-Alawi, M., Walsh, M. T., Hannigan, K., Glynn, S., Thornton, M., McQuaid, S., Wang, Y., Hamilton, P. W., Verriere, V., Gleich, G. J., Harvey, B. J., Costello, R. W., and McGarvey, L. P.
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- 2012
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8. A consistent scalar-tensor cosmology for inflation, dark energy and the Hubble parameter
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Wang, C.H.-T., Reid, J.A., Murphy, A.St.J., Rodrigues, D., Al Alawi, M., Bingham, R., Mendonça, J.T., and Davies, T.B.
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- 2016
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9. "Integrating weather in modelling earthmoving mining operation using distributed simulation with HLA standards"
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AL-Alawi, M., primary, Mohamed, Y., additional, and Bouferguene, A., additional
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- 2018
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10. Personality Traits and Specialty Choice Among Oman Medical Specialty Board Residents
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Al Alawi, M., primary, Al Sinawi, H., additional, and Al Huseini, S., additional
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- 2017
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11. Assuring Efficient PDC Drilling
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Curry, D, additional, Pessier, R, additional, Spencer, R, additional, Al Alawi, M, additional, Wingate, J, additional, and Kuesters, A, additional
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- 2017
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12. Evaluation of the efficacy of transcricoid lignocaine as adjunctive local anaesthesia for fiberoptic bronchoscopy
- Author
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Hamad, S., primary, Al-Alawi, M., additional, Devaney, N., additional, Subramaniam, A., additional, and Lane, S., additional
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- 2014
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13. Eosinophil peroxidase induces the expression and function of acid-sensing ion channel-3 in allergic rhinitis:in vitroevidence in cultured epithelial cells
- Author
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G. Khoo, S., primary, Al-Alawi, M., additional, Walsh, M. T., additional, Hennigan, K., additional, Glynn, S., additional, Thornton, M., additional, McQuaid, S., additional, Wang, Y., additional, Hamilton, P. W., additional, Verriere, V., additional, Gleich, G. J., additional, Harvey, B. J., additional, Costello, R. W., additional, and McGarvey, L. P., additional
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- 2012
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14. Pleural Fluid Analysis: Standstill or a Work in Progress?
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Hassan, T., primary, Al-Alawi, M., additional, Chotirmall, S. H., additional, and McElvaney, N. G., additional
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- 2012
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15. Experimental Investigation and Failure Analysis of Fastened GRP under Bending Using Finite Element Method and Artificial Neural Networks
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Abdennour, C. Seibi, primary and Al-Alawi, M., additional
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- 1999
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16. Systematic Study of Iron Control Chemicals Used During Well Stimulation
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Taylor, K. C., primary, Nasr-El-Din, H. A., additional, and Al-Alawi, M. J., additional
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- 1999
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17. A Systematic Study of Iron Control Chemicals Used During Well Stimulation
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Taylor, K. C., additional, Nasr-El-Din, H. A., additional, and Al-Alawi, M. J., additional
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- 1998
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18. Eosinophil peroxidase induces the expression and function of acid-sensing ion channel-3 in allergic rhinitis: in vitro evidence in cultured epithelial cells.
- Author
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G. Khoo, S., Al-Alawi, M., Walsh, M. T., Hannigan, K., Glynn, S., Thornton, M., McQuaid, S., Wang, Y., Hamilton, P. W., Verriere, V., Gleich, G. J., Harvey, B. J., Costello, R. W., and McGarvey, L. P.
- Subjects
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ACID-sensing ion channels , *ALLERGIC rhinitis , *NASAL mucosa , *LACTIC acid , *EPITHELIAL cells - Abstract
Background Acid-sensing ion channels ( ASIC) are a family of acid-activated ligand-gated cation channels. As tissue acidosis is a feature of inflammatory conditions, such as allergic rhinitis ( AR), we investigated the expression and function of these channels in AR. Objectives The aim of the study was to assess expression and function of ASIC channels in the nasal mucosa of control and AR subjects. Methods Immunohistochemical localization of ASIC receptors and functional responses to lactic acid application were investigated. In vitro studies on cultured epithelial cells were performed to assess underlying mechanisms of ASIC function. Results Lactic acid at pH 7.03 induced a significant rise in nasal fluid secretion that was inhibited by pre-treatment with the ASIC inhibitor amiloride in AR subjects ( n = 19). Quantitative PCR on cDNA isolated from nasal biopsies from control and AR subjects demonstrated that ASIC-1 was equally expressed in both populations, but ASIC-3 was significantly more highly expressed in AR ( P < 0.02). Immunohistochemistry confirmed significantly higher ASIC-3 protein expression on nasal epithelial cells in AR patients than controls ( P < 0.01). Immunoreactivity for EPO+ eosinophils in both nasal epithelium and submucosa was more prominent in AR compared with controls. A mechanism of induction of ASIC-3 expression relevant to AR was suggested by the finding that eosinophil peroxidase ( EPO), acting via ERK1/2, induced the expression of ASIC-3 in epithelial cells. Furthermore, using a quantitative functional measure of epithelial cell secretory function in vitro, EPO increased the air-surface liquid depth via an ASIC-dependent chloride secretory pathway. Conclusions This data suggests a possible mechanism for the observed association of eosinophils and rhinorrhoea in AR and is manifested through enhanced ASIC-3 expression. [ABSTRACT FROM AUTHOR]
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- 2012
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19. Sustained expression of steroid receptor coactivator SRC-2/TIF-2 is associated with better prognosis in malignant pleural mesothelioma.
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Jennings CJ, O'Grady A, Cummins R, Murer B, Al-Alawi M, Madden SF, Mutti L, Harvey BJ, Thomas W, and Kay EW
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- 2012
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20. Effect of organic fertilizer and compound in some growth characteristics of wheat crop Triticum aestivuml
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Abdel-Kadhim, K. A. -H, Al-Alawi, M. S., and Jubair, A. R.
21. Emerging Burden of Frail Young and Elderly Persons in Oman: For whom the bell tolls?
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Al-Sinawi, H., Al-Alawi, M., Al-Lawati, R., Al-Harrasi, A., Al-Shafaee, M., and Samir Al-Adawi
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Disability ,Oman ,lcsh:R ,oman ,Sounding Board ,transition, demographic ,lcsh:Medicine ,Non-communicable diseases ,Burden of illness ,Transition demographic ,Chronic disease - Abstract
Recent improvements in health and an increased standard of living in Oman have led to a reduction in environment-related and infectious diseases. Now the country is experiencing an epidemiological transition characterised by a baby boom, youth bulge and increasing longevity. Common wisdom would therefore suggest that Omanis will suffer less ill health. However, a survey of literature suggests that chronic non-communicable diseases are unexpectedly becoming common. This is possibly fuelled by some socio-cultural patterns specific to Oman, as well as the shortcomings of the ‘miracle’ of health and rapid modernisation. Unfortunately, such new diseases do not spare younger people; a proportion of them will need the type of care usually reserved for the elderly. In addition, due to their pervasive and refractory nature, these chronic non-communicable diseases seem impervious to the prevailing ‘cure-oriented’ health care system. This situation therefore calls for a paradigm shift: a health care system that goes beyond a traditional cure-orientation to provide care services for the chronically sick of all ages.
22. Analysis of the impact of CO 2-based demand-controlled ventilation strategies on energy consumption
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MONCEF KRARTI and Al-Alawi, M.
23. Management of primary spontaneous pneumothorax: an audit into practice
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Al-Alawi, M., Abirami Subramaniam, Khan, R., Moloney, E., and Lane, S. J.
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Adult ,Male ,Medical Audit ,Young Adult ,Practice Guidelines as Topic ,Humans ,Pneumothorax ,Female ,Guideline Adherence ,Retrospective Studies
24. Effect of spraying iron and zinc concentrations in grain and leaf content for two varieties of wheat crop
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Bushra Alwan, Abdul Kazem, K. A. H., Al-Alawi, M. S., and Jubair, A. R.
25. The lipoxin A4 increases ASL height in normal and cystic fibrosis bronchial epithelium.
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Verriere, V,, Higgins, G., Al Alawi, M., Costello, R., Chiron, R., Harvey, B., and Urbach, V.
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- 2011
26. Management of primary spontaneous pneumothorax: an audit into practice.
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Al-Alawi, M, Subramaniam, A, Khan, R, Moloney, E, and Lane, S J
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- 2013
27. Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
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Labeau, Sonia O, Afonso, Elsa, Benbenishty, Julie, Blackwood, Bronagh, Boulanger, Carole, Brett, Stephen J, Calvino-Gunther, Silvia, Chaboyer, Wendy, Coyer, Fiona, Deschepper, Mieke, François, Guy, Honore, Patrick M, Jankovic, Radmilo, Khanna, Ashish K, Llaurado-Serra, Mireia, Lin, Frances, Rose, Louise, Rubulotta, Francesca, Saager, Leif, Williams, Ged, Blot, Stijn I, Dritan, Muzha, Antoni Margarit Ribas, Fernando, Lipovesty, Cecilia, Loudet, Fiona, Coyer, Philipp, Eller, Nafseen, Mostafa, Patrick, M Honoré, Vanesa Mercado Telleria, Jasmina, Smajic, Paula Cristina Nogueira, Khalid Mahmood Khan Nafees, Romuald, Hentchoya, Louise, Rose, Javiera, Soledad, Frances, Lin, Yenny, Cardenas, Amylkar Garay Reyes, Alan, Sustic, Meropi, Mpouzika, Tamas, Vymazal, Hanne Irene Jensen, Hernan, Aguirre-Bermeo, Liivi, Maddison, Maija, Valta, Silvia, Calvino-Gunther, Frank, Bloos, Faustina Excel Adipa, Vasilios, Koulouras, Judy, Enamorado, Zsuzsann, Ágoston, Hrönn, Birgisdóttir, Amit, Gupta, Mohan, Gurjar, Bram, Kilapong, Seyed Mohammadreza Hashemian, Ignacio, Martin-Loeches, Julie, Benbenishty, Andrea, Cortegiani, Kelly, Fletcher, Yoshiro, Hayashi, Wangari, Waweru-Siika, Khalid, Abidi, Sang-Min, Lee, Burhan, Hadri, Mihails, Dolgusevs, Fayez François Abillama, Tomas, Jovaisa, Cyril, Thix, Muhammed, Elhadi, Basri Mat Nor, Shanti, Ratnam, Mohd Zulfakar Mazlan, Sundaresan, Maiyalagan, Luis, Sánchez-Hurtado, Adrian, Belii, Mendsaikhan, Naranpurev, Prabha, Gautam, Dylan De Lange, Rachael, Parke, Rose Ekama Ilesanmi, Mirjana, Shosholcheva, Antonija, Petosic, Ranveig, Lind, Madiha Hashmi Ffarcsi, Javier, Bogarin, Aaron Mark Hernandez, Malgorzata, Mikaszewska-Sokolewicz, Bruno, Sousa, Dana, Tomescu, Dorel, Sandesc, Theogene, Twagirumugabe, Vitaly, Gusarov, Maie, Ebaid, Radmilo, Jankovic, Gari, Slobodianiuk, Andrea, Martonova, Rihard, Knafelj, Mervyn, Mer, Emilio, Maseda, Bernardo, Panka, Joerg, C Schefold, Eva, Joelsson-Alm, Konlawij, Trongtrakul, Lorna, Merritt-Charles, Lamia Ouanes Besbes, Yalım, Dikmen, Lesia, Zgrzheblovska, Mark, Fielding, Francesca, Rubulotta, Ashish, K Khanna, Leif, Saager, Ingrid von der Osten, Alban, Greca, Alma, Cani, Nordian, Xhindi, Genci, Hyska, Antonio Margarit Ribas, Susana, Pinto, Paulo, Alves, Romina, Esposito, Emanuel, Valgolio, John Thomas Sanchez Minope, Antonio, Abdala, Maria, Ayala, Silvina, Bravo, Ana, Bantar, Patricia, Delgado, Gustavo, Badariotti, Fernando, Lipovestky, Ana, Diaz, Pablo, Saul, Mariano, Setten, Alejandra, Aucapina, Ysica, Acosta, Victor, Gonzalez, Luis, Camputaro, Fernando, Baccaro, Robert, Villa, Marcela, Mastantuono, Emiliano, Dean, Oscar Fernández Rostello, Patricia, Brizuela, Julio Ricardo Bartoli, Matias, Guereschi, Cristian, Quiroga, Sofia, Putruele, Paula, Villegas, Veronica, Curilen, Ruben, Fernandez, Mariangeles Gabriela Nocheretti, Rosana Gabriela Escalante, Cecilia Inés Loudet, Silvia, Fernandez, Ana Laura Gonzalez, Gustavo Andres Alvarez, Federico, Iglesias, Silvia, Chaparro, Graciela, Zakalik, Gonzalo, Pagella, Matías, Baini, Pierina Arias Campos, Ignacio, Sabbag, Armando, Schmukler, Imelda Perdomo Fonseca, Gonzalo Martín Alvarez, Mario, Ramirez, Fernando, Tapia, Carlos Alejandro Bascary, Graciela Del Valle Gimenez, Fernando Pablo Bertoletti, Esteban, Milioto, Pablo Julio Maldonaldo Bonsignore, Maria Alejandra Fernandez, Julie, Smith, Tim, Chimunda, Lorraine, Thompson, Teena, Maguire, Wendy, Chaboyer, Stacey, Watts, Marion, Mitchell, Madeleine, Powell, India, Lye, Leanne, Parsons, Nerilee, Baker, Claire, Reynolds, Amy, Thompson, Kristy, Masters, Kellie, Sosnowski, Lynette, Morrison, Gavin, D Leslie, Ramanathan, Lakshmanan, Alexis, Tabah, Wendy, Brown, Sharon, McDowell-Skaines, Andrea, Mclucas, Chris, Smith, Mandy, Tallot, Sarah, Jones, Michelle, Barakat-Johnson, Thomas, Leong, Rand, Butcher, Kerrie, Martin, Philipp, Douschan, Dirk von Lewinski, René, Schmutz, Uta, Kolussi, Fatema, Salman, Zainab, Ateya, Koen De Decker, Niels Van Regenmortel, Anita, Jans, Patricia, Wijnands, Stefano, Coremans, Patrick, M Honore, David De Bels, Tanja, Depuydt, Caroline, Paillet, Luc-Marie, Jacquet, Walter, Swinnen, Francis, Hannes, Matthia, Mergeay, Stijn Van de Velde, Silvie, Allaert, Pieter, Hoste, Christophe, Borin, Sandrine, Balon, Vincent, Fraipont, Patrick, Biston, Nicolas De Schryver, Thierry, Dugernier, Ilse Van Cotthem, Angelica Olivetto de Almeida, Silvia Angelica Jorge, Delmiro, Becker, Raysa Cristina Schmidt, Evellyn, Oliveira, Aline, Ramalho, Eliane, Mazocoli, Audrey, Fioretti, Elaine, Barros, Leticia, Serpa, Suzana, Bianchini, Ticiane, Campanili, Taís, Pantaleao, Paulo Carlos Garcia, Ana Lucia Vitti Ronchini, Rayanne, Santos, Nurulhuda Binti, A Manap, Sean, Bagshaw, Dominic, Carney, Jon, Davidow, Ella, Rokosh, Andréa Maria Laizner, Samantha, Smith, Megan, Mcquirter, Betty Star Kampayana, René, Favre, Martin, Sills, Julie, Dallaire, Cathy, Becker, Sherissa, Microys, Bonnie, Bowes, Jennifer, Lajeunesse, Rishi, Ghosh, Jacqueline, Baptiste-Savoie, Rose, Raizman, Gabriel, Suen, Noushin, Taghavi, Orla, Smith, Clare, Fielding, Julieta, Canales, Pia, Molina, Javiera, Chaparro, Maria Idalia Sepulveda, Matias Jesús Flamm Zamorano, Pamela, Rocha, Ximena, Villanueva, Paola, Araya, Meneses, Dayan, Fernando, Avalos, Xiaohan, Li, Liu, Yu, Xinxia, Li, Xiaoyan, Chen, Zhixia, Jiang, Jing, Yang, Jingfang, Chen, Lei, Yang, Kefang, Wang, Jie, Gao, Xiuhua, Fang, Ronghua, Zhao, Xinhua, Xia, Hongmei, Liu, Jing, Li, Haiyan, Wang, Gen, Meng, Yanhong, Di, Damei, Wang, Rong Hua Zhao, Li Ping Hu, Peipei, Xu, Qing Feng Jiao, Hai Yun Wang, Chun Jie Xia, Yan, Liu, Mei, Ye, Yan, Wan, Wenmei, Wang, Yajun, Ding, Aiua, Ren, Yan, Gao, Qi, Li, Guifang, Du, Yanling, Shen, Yanming, Ding, Ning, Li, Cui, Yuan, Lei, Tan, Qiang, Lin, Hailing, Guo, Howe, Yan, Xiao, Xu, Wei, Zhang, Jinxian, Liang, Libing, Zhang, Eryun, Tian, Qian, Zhao, Lin, Insu, Jingwen, Dong, Yanmei, Gu, Ying, Liu, Lina, Zhao, Wei, Wang, Hongmei, Qiao, Lili, Tuo, Mengmeng, Lv, Jin Yu Zhu, Jifen, Zhu, Ying, Wei, Man, Liu, Yin, He, Jiyin, Cheng, Jin, Liu, Jia, Na, Dongfang, Wei, Qing, Li, Xiaoying, Wu, Huan, Duan, Dongliang, Lin, Qiong, Liang, Xiaofang, Luo, Yunfeng, Xiong, Rong Fen Huang, Jing, Fu, Tao, Zan, Man, Ye, Zeya, Shi, Yanfei, Long, Yang, Lei, Xiaodi, Liu, Chen, Yumei, Lingling, Wang, Yali, Zhang, Yan, Xu, Cheng, Wang, Zhijuan, Chengxia, Sun, Jinhui, Song, Yingli, Wang, Xiumei, Liu, Yupeng, Liu, Yuxia, Yuan, Qingping, Huang, Fengling, Yang, Yun, Wu, Xianping, Luo, Xiaowu, Bai, Hong, Zheng, Min, Song, Yue, Sun, Zhangshuangzi, Li, Feifei, Luo, Miao, Liu, Li Chuntang Li, Xinjian, Li, Guiping, Zhang, Lina, Xiao, Tingting, Yu, Guangyuan, Gao, Wei, Wei, Fanglan, Wang, Ting, Han, Tingting, Li, Zeng, Qi, Jing Mei Zeng, Yan, Long, Fuqun, Pan, Jing, Wang, Guoxue, He, Haiyan, Chen, Feifei, Zhang, Chao, Yu, Gao, Chunhua, Xiuying, Yao, Dongmei, Bai, Liu, Lu, Xuelian, Xu, Yan, Wang, Xuejuan, Liang, Zhang, Na, Aizhi, Zhang, Xiaochun, Hu, Hui, Zhang, Ruixia, Wang, Poon Shing Tak, Sung Wai Ho, Qun Xia 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Kjærgård, Britta, Jepsen, Birthe, Husted, Morten, Bestle, Anne Marie Kodal, Tina Charlotte Bitsch Hansen, Anne Sofie Bomholt Pedersen, Tina Damgaar Thomsen, Anisette, Hoegenhaven, Mette, From, Tine Melgaard Frandsen, Grit, Henning, Anja, Hansen, Inger Abildgaard Bliksted, Luis Mario Tamayo, Pedro, Mogrovejo, Carolina, Palaez, Diego Rolando Morocho Tutillo, Cintia Valencia Hurtado, Maria Fernanda García, Diana, Alvarez, Fausto, Guerrero, Alexandra, Vasquez, Martin, Kütimets, Kadri, Tamme, Eneli, Anvelt, Lomangisi, Dlamini-Sserumaga, Carita, Löfqvist, Virpi, Lusenius, Outi, Kauppi, Jenni-Katarina, Sakki, Tarja, Tervo-Heikkinen, Ulla, Kesti, Merja, Merilainen, Elina, Karjula, Minna, Peltomaa, Auli, Palmu, Maarit, Ahtiala, Maija Anniina Valta, Hervé, Mentec, Gaëtan, Plantefève, Guillaume, Besch, Sébastien, Pili-Floury, Stanislas, Ledochowski, Marc Danguy des Déserts, Christophe, Giacardi, Cédric, Daubin, Audrey, Massard, Yann Le Guen, Agnès, Blanc, Simon, Mandaroux, Silvia Calvino Günther, 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Mirabella, Laura, Maulicino, Giancarlo, Abregal, Maria, Donvito, Paolo, D'Ambrosio, Filipo, Binda, Ileana, Adamina, Alessandro, Galazzi, Alessandra, Negro, Rosanna, Vaschetto, Fabio, Capuzzi, Margherita, Boschetto, Lucia, Stivanello, Luciano, Bonaccorso, Chiara, Megna, Pasquale, Iozzo, Antonino, Rizzo, Giovanni, Scire, Maria Rosa Taibi, Francesca Paola Tranello, Antonio, Manzo, Lidia, Traina, Beatrice, Pastore, Attilio, Quaini, Gian Domenico Giusti, Gloria, Montaldi, Federica, Piergentili, Federica, Mancini, Simona, Casaioli, Francesco, Uccelli, Fabio, Guarracino, Adriana, Onelli, Valentina Di Gravio, Maria, Cossu, Oliva, Matrona, Monica, Rocco, Daniela, Alampi, Federica, Dellafiore, Flavia, Ranalli, Matteo, Bossolasco, Elisabetta, Brizio, Pina, Migliorino, Paolo, Cortellazi, Moris, Rosati, Francesco, D'Ambrosio, Catia, Quagliotto, Erik, Roman-Pognuz, Alberto, Peratoner, De Rosa, Silvia, Marina Alessandra Martin, Francesca De Sanctis, Paolo, Ciorba, Patrick, Toppin, Hyacinth, Harding-Goldson, Shunsuke, Taito, Nobuaki, Shime, Ryohey, Yamamoto, Fumiya, Kanda, Akemi, Hirao, Moritoki, Egi, Ayako, Noguchi, Satoru, Hashimoto, Umeda, Aya, Hideaki, Sakuramoto, Akira, Ohuchi, Jun, Kataoka, Kumi, Maruyama, Izumi, Nakayama, Yoshimasa, Nishime, Koji, Fujimoto, Kenji, Takahashi, Mayumi, Tsujimoto, Masako, Shimizu, Eunice, Tole, Malcolm, C Correia, Je Hyeong Kim, Sunghoon, Park, Kyung Chan Kim, Jonghyun, Baek, Jung-Min, Bae, So Young Park, Tai Sun Park, Heung Bum Lee, Seung Yong Park, Jisoo, Park, Lee, Yeon-Joo, Cho, Young-Jae, Sang-Miin, Lee, Kyeongman, Jeon, Seok Chan Kim, Jongmin, Lee, Hyun Keun Chee, Jin Won Huh, Yun Su Sim, Junghyun, Kim, Youjin, Chang, Jong-Joon, Ahn, Byung Ju Kang, Won-Yeon, Lee, Seok Jeong Lee, Nehat, Baftiu, Ivasr, Krastins, Sonia, Stiban, Michel El Feghaly, Elie, Gharios, Marie, Merheb, Mohamed, Benlamin, Ala, Khaled, Wesal Ali Belkhair, Majd, Tabib, Firas, Ashour, Ahmed, Elhadi, Osama Wanees Emhemid Tababa, Taha, Khaled, Soad Imhmed, R Alkhumsi, Abdualhamid, I Alshrif, Ahmed Ali Aboufray, Aya, Alabuzidi, Ahmed Ramadan Triki, Mala, Elgammudi, Hajer Ben Zahra, Enas, Soula, Maram Milud Said Al-Alawi, Hazem, Ahmed, Mohamed Abdurazzag Ali Ghula, Saulius, Vosylius, Lucie, Mouton, Touraj, Rastegar, Claude, Sertznig, Gilles, Martin, Christian, Theisen, Christian, Ferretti, Fränk, Gils, Marc, Gallion, Asmah, Zainudin, Laila Kamaliah Kamalul Bahrin, Shanti Rudra Deva, Azmin Huda Abdul Rahim, Sherliza, Wahab, W Nazaruddin, W Hassan, Wan Nasrudin Wan Ismail, Mohd Nazri Ali, Tien Meng Khoo, Noryani Mohd Samat, Jenny May Geok Tong, Nik Azman Nik Adib, Mohd Basri Mat Nor, Shanthi, Ratnam, Nahla, Ismail, Siti Rohayah Sulaiman, Kit Weng Foong, Anita, Alias, Ngu Pei Hua, Jorge Macias Zermeno, Daniel, Blanco, Karely, Duran, Claudia Lizbeth Lopez Nava, San Juan Roman Nandyelly, Luis Alejandro Sanchez-Hurtado, Brigitte, Tejeda-Huezo, Mario Del Moral Armengol, Luis Pedro Ambriz Nava, Jorge Guerra Herrera, Gilberto Felipe Vazquez de Anda, Humberto, Gallegos-Perez, Nancy, Hernandez-Sanchez, Lucia, Hernandez-Ponce, Luis, Gorordo-Delsol, Marcos, Hernandez-Romero, Saira, Gomez, Fernando, Molinar, Silvio, A Ñamendys-Silva, Juan, P Romero-Gonzalez, Daira, Gonzalez, Antonio, Landaverde, Miguel Ángel Sosa, Berenice, Navarro, José Ivan Rodriguez de Molina Serrano, Sergio Reyes Iburrigarro, Alejandro, Ibarra, Joaquin, Aguirre, Mayra, Martinez-Gonzalez, Nayeli Rocio Cañas Padilla, Ana Alícia Velarde Pineda, Missael Vladimir Espinoza Villafuerte, María Ocotlan Gonzalez Herrera, Battsetseg, Baasanjav, Abdelhamid, Hachimi, Mina, Elkhayari, Tarek, Dendane, Nisha Bhandari Subedi, Sabina Dhakal Pathak, Meena, Manandhar, Laura Van Gulik, Mark Van Den Brink, Peter Van Vliet, Benjamin, Gerretsen, Lettie Van Den Berg, Marina De Haan, Binny, Tuinstra, Paul, Kuijpers, Jennifer, Reijntjens, Jan Wytze Vermeijden, Martin, Rinket, Margijske, Vanroest, Auke, Reidinga, Bert, Loef, Willem, Dieperink, Marisa, Onrust, Tom, Dormans, Laura, Bormans, Matty, Koopmans, Rik, T Gerritsen, Arlette Van Den Elst, Mirjam, Evers, Oscar, Oiting, Rob, Wilting, Bart, Ramaker, Mark van der Kuil, Jan-Willem, Fijen, Lenneke, Haas, Jasper, Haringman, Lynette, Newby, Eileen, Gilder, Danielle, Hacking, Rica, Dagooc, Rima, Song, Hansjoerg, Waibel, Frances, Dawn, Jackie, Rapley, Llesley, Chadwick, Carmel, Chapman, Petra, Crone, Jonathan, Albrett, Peter, Marko, Jennifer, Goodson, Troy, Browne, Richard, Whitticase, Cheryl, Davidson, Harriet, Judd, Daniel, Owens, Tonia, Onyeka, Innocent, Ugwu, Rose, Ilesanmi, Prisca Olabisi Adejumo, Afolabi, Owojuyigbe, Anthony, Adenekan, Stella, Uba, Christiana, Chime, Deborah, Jibrin, Babangida John Sankey, Oyebola, Adekola, Simeon, Olanipekun, Mirjana, Shosolcheva, Vanja, Gievski, Andrijan, Kartalov, Filip, Naumovski, Biljana, Kuzmanovska, Angela, Trposak, Zaneta, Bogoevska-Miteva, Rodney, Rosalia, Brita Fosser Olsen, Britt, Sjobo, Karianne Dale Jensen, Drammen, Sykehus, Birgitte Fosser Johansen, Esben, Straede, Edda, Johansen, Inger Johanne Finnstrom, Annette, Toellefsen, Hege, Ostenjo, Hege, Bjorgen, Bjorn, Bratsberg, Elin, Kristoffersen, Elin Mari Skorstad, Siri, Hansen, Sylvi, Vullum, Gro Anne Lunde, Wenche, Arntsen, Mette, Lund, Gro Ringstad Akselsen, Kristina Reinertsen Monstad, Ane, Stenset, Hanne, Haugom, Bjoern, Monsen, Lisa, Høgvall, Siw, Trudvang, Britt, Galaaen, Siv Karin Malmin, Marit Hildegunn Andersen, Rita Foss Hargott, Yvonne, Andersen, Elin, Steffenak, Marit, Nyhus, Barbro, Meland, Madiha, Hashmi, Noelia, Rivas, Elizabeth, Maidana, Alberto de Jesús Ortiz, Dolly Mabel Bordon Cabral, Marcelo, Simi, Cesar, Aponte, Juan Carlos Rivas, Sirley, Gill, Amilcar, Garcia, Gloria, Alvarenga, Laura, Cespedes, Hugo, Perez, Maria Liz Moreira, Fidelina, Canete, Roberto, Gonzalez, Natalia, Monges, Mary, Coman, Marcelo, Pederzani, Natalia, Franco, Ferdinand, Aganon, Regina, Martinez, Debbie, Noblezada-Uy, Chris Gerome Ellazar, Franklin Dean Cerezo, Jose Emmanuel Palo, Cristal April Jane Aperocho, Michael, Isanan, Marta, Tubacka, Przemyslaw, Jasiewicz, Miroslaw, Czuczwar, Michal, Borys, Aleksandra, Gutysz-Wojnicka, Lidia, Glinka, Ryszard, Gawda, Jan, Bilawicz, Paula, Cabrita, João, Vieira, Margarida Ferreira Figueiredo, Cristiana Mota Pinheiro, Nelson, Antunes, Laura, Pedro, Fatima, Ferreira, Isabel, Parente, Maria, Varela, Fatima, Fernandes, Claudia, Martins, Abel, Viveiros, Raquel, Cavaco, Clara Santa Rita, Sofia, Dias, Ana Margarida Feranandes, Pedro, Silva, Catarina, Nunes, João, Cabral, Filpe, Pires, Hilaryano, Ferreira, Jacinta, Santos, Vitor Manuel Vaz Pinto, Bruno Miguel Bispo, Amelia, Ferreira, Elena, Molinos, Estevão, Lafuente, Ricardo, Gregorio, Humberto, Costa, Ângela, Lima, Susana, Ferreira, Vanda, Seromenho, Eulália, Luis, Idália, Valerio, Helena, Cesar, Ana, Tavares, Ahmed Subhy Alsheikhly, Saeed, Mahmood, Catalin Traian Guran, Alida, Moise, Daniela Carmen Filipescu, Mihail, Luchian, Mihai, Popescu, Monica Adriana Scutariu, Cristina, Petrisor, Natalia, Hagau, Ioana, Grigoras, Tatiana, Patrichi, Vitaly, Gusarev, Alexandra, Pivkina, Vladimir, Kulakov, Olga, Ignatenko, Julia, Kovaleva, Trina, Zhivotneva, Marina, Zhedaeva, Nikita, Matiushkov, Olga, Ershova, Natalya, Egorova, Victoria, Khoronenko, Danil, Baskakov, Dmitry, Sergeev, Michael, Piradov, Liudmila, Grishina, Marat, Magomedov, Evgeniy, Zuev, Uri, Gorokhovatsky, Anna, Leonova, Liudmila, Fadeeva, Vladislav, Belskiy, Dmitriy, Galishevskiy, Nadezhda, Zubareva, Maksim, Tribulev, Oksana, Zueva, Alexander, Kiselev, Nikolaj, Kamenshchikov, Ekaterina, Tokareva, Maxim, Petrushin, Irina, Starchenko, Isaac, Nshimyumuremyi, Jerome, Muhizi, Egide, Buregeya, Josue, Nzarora, Amer, Assiri, Maie Salem Ebaid, Ghaleb, Almekhlafi, Yasser, Mandourah, Jelena, Velickovic, Dejan, Veličković, Bojan, Jovanovic, Adi, Hadzibegovic, Branislava, Stefanovic, Vanja, Misic, Vesna, Bumbasirevic, Marija, Rajković, Milena, Stojanovic, Srđan, Gavrilovic, Maja, Stanojević, Aktham, Yaghi, Anton, Turčan, Peter, Firment, Garri, Slobodianiuk, Daria, Rabarova, Danca, Lančaričová, Janko, Vlaovic, Matjaž, Groznik, Milica, Lukic, Janja, Perme, Maja, Sostaric, Nejc, Umek, Tomislav, Mirkovic, Simon, Dolenc, Misa, Fister, Nika, Zorko, Andrej, Markota, Nomhle Princess Yeni, Phumele, Jali, Shelley, Schmollgruber, Muhommed Ridwaan Syed, Nivisha, Parag, Robert, Wise, Maria, Galiana, José Alejandro Navarro, Ana María De Pablo, Patricia, Albert, Pilar, Martinez, Yolanda, Mendiara, Barbara, Garcia, Ana Alabart Llinas, Marilyn, Riveiro, Elisabet, Gallart, Alba, Riera, Miquel, Sanz, Swagotika, Salo, Miguel Angel Gimenez Lajara, Montserrat Venturas Nieto, Rosa, Garcia, José Manuel Garcia Pena, Maria Carmen Gorgolas, Maria Aranzazu Isasi, Rafael, Sierra, Federico, Gordo, Isabel, Conejo, Vicent, Salvà-Costa, Carolina, Garzón-Tovar, Sara, Lospitao, Rafael, Gonzalez, Pedro, Gutierrez, Mercè, Girona, Jordi, Adamuz, Pablo Garcia Olivares, José Peral Gutierrez de Ceballos, Celia, Tirado, Irene De Wit, Ana Belén Curto Polo, Maria Del Mar Diaz Salcedo, Javier, Ripolles-Melchor, Eugenio, Martinez-Hurtado, Jorge Duerto Alvarez, María Luisa Bravo Arcas, Juan Ignacio Torres Gonzalez, Ana Belén Sánchez de la Ventana, Pablo Lopez-Arcas Calleja, Raquel Garcia Alvarez, Purificacion Sanchez Zamora, Alvaro Ortega Guerrero, Rosario, Cosano, Jonathan, Perez-Vacas, Margarita, Campos-Perez, Emma Moreno Barreiro, Losune Cano Sanchez, Monica Garcia Diaz, Raquel, Jimenez, Lorena Del Rio Cabajo, Daniel Sancho Muriel, Helena Fernandez Alonso, Ana Wensell Fernández, Isabel Santín Piñan, Guillermo Muñiz Albaiceta, Maria Cristina Iglesias Fernandez, Francisco Javier Saenz Abos, Pablo, Monedero, Ramon Molina Chueca, Lydia Gallego Aguirre, Silvia Call Manosa, Carmen Partera Luque, Neus, Calpe, Monica Recio Losilla, Meritxell Tapia Fores, Olga, Farre, Oscar, Fernandez, M Del Rosario Villar Redondo, Donaldo, S Arteta Arteta, Maria Angeles Hurtado Sanchez, Cristina Paños Espinosa, Laura Martinez Reyes, Laura Claramunt Domenech, Carmen Velasco Guillén, Josep Trenado Alvarez, Mercedes Del Cotillo, Jesus Emilio Barrueco-Francioni, Belen Burgos Conde, Maria Pilar Sogues Blanco, Maria Luisa Blasco, Ana Isabel Clement, Clara, Hurtado, Luz Coronado Sanz, David, Perez-Torres, Estefanía, Prol-Silva, Jorge, Pereira, Iván Areán González, Anastasio Espejo Cano, Cesar Rodriguez Nuñez, Inmaculada Lorenzo Fernadez, Alejandra Azahara Marguello Fernandez, Rosa Del Bosque Diez, Badiola, Hilario, Begoña, Zalba-Etayo, Ana, Pascual-Bielsa, Preveen, Banwarie, Dick, Nahar, Alisha van Axel, Naraindath, N Boedjawan, Erika Backlund Jansson, Ann-Sofie, Malvemyr, Lotta, Johansson, Ulla, Sandberg, Catarina, Tingsvik, Gunilla, Mattsson, Gun, Löf, Martin, Spångfors, Mona, Ringdal, Sebastian, Geijer, Lotti, Orvelius, Mia, Hylen, Caroline, Lagerhäll, Eva, Åkerman, Viveca Hamback Hellkvist, Ulrica, Mickelsson, Ewa, Wahlbom, Ing-Marie, Larsson, Ewa, Wallin, Filippo, Boroli, Solenne, Ory, Margaret Lynn Jong, Alexander, Dullenkopf, Martin, Lang, Yvan, Fleury, Marianne, Maus, Nawfel, Ben-Hamouda, Anne, Fishman, Mei Yu Hsu, Shu Chuan Chang, Konlawij, Trongtratul, Chaiwut, Sawawiboon, Sunthiti, Morakul, Bodin, Khwannimit, Keevan, Singh, Dale, Ventour, Dianne, Figaro-Barclay, Sasha, Sankar-Maharaj, Mhamed Sami Mebazaa, Salma, Kamoun, Souheil, Elatrous, Lamia, Besbes, Fekri, Abroug, Walid, Naija, Youssef Zied Elhechmi, Walid, Sellami, Zied, Hajjej, Takoua, Merhabene, Imen, Talik, Ozlem Ozkan Kuscu, Ozcengiz, Dilek, Avşar, Zerman, Hayriye Cankar Dal, Sema, Turan, Semih, Aydemir, Hakan, Yilmaz, Duygu Kayar Calili, Seval, İzdes, Melike, Cengiz, Ayça, Gümüş, Banu, Taşdemir, Ali, Kağnıcı, Mustafa, Ay, Serap Avcı Ay, Gulbahar, Caliskan, Turkay, Akbas, Abidin Oner Balbay, Serdar, Efe, Volkan, Inal, Gülseren, Elay, Pınar, Karabacak, Boğaç, Özserezli, Evren, Şentürk, Oktay, Demirkiran, Suha, Bozbay, Elif, Erdogan, Mustafa, Akker, Nebia, Peker, Asu, Ozgultekin, Sibel Ocak Serin, Can, Turan, Gulsah, Karaoren, Senay, Goksu, Sait, Karakurt, Huseyin, Arikan, Fethi, Gül, İsmail, Cinel, Iskender, Kara, Hasan Nabi Undar, Yesim Serife Bayraktar, Jale Bengi Çelik, Murat Emre Tokur, Demet Tok Aydin, İsmail, Yildiz, Beysim, Özcan, Başar, Erdivanli, Ahmet, Eroglu, Devrim, Akdağ, Nurdan, Ünlü, Adonis, Dungca, Ashwaq, Ali, Bindu, Thankamma, Paul Eric Reyes, Sini, John, Ajitha, Rajendran, Fatima Kasem El Ahmad, Kathleen Ann Smiley, Susanna, Hojden, Mia Thorning Miller, Vishnu Das Sasidharan Nair, Maria Gracia San Antonio, Khaled Al Qawasmeh, Sabah Abu Shawish, Hilary, Twiggs, Ines, Rosado, Volodymyr, Babych, Faye, Morren, Charlotte, Young, Nicola, Vaughan-Jones, Stephanie, Harris, Karen, Burns, Carmel, Georgiev, Rosina, Shayamano, Ian, Kerslake, Peter, Creber, Ana, Vochin, Catherine, O'Brien, Paul, Caddell, Samantha, Hagan, Mandy, Hughes, Tomasz, Torlinski, James, Sherwin, Santhana, Kannan, Amber, Markham, Richard, Lebon, Jason, Cupitt, Julius, Cranshaw, Nigel, White, Victoria, Marriott, Wendy, Milner, Casiano Barrera Groba, Joao, Azoia, Petra, Polgarova, Shaly, George, Ritoo, Kapoor, Ceri, Lynch, Nathalie, Fox, Karen, Cranmer, Natalie, Fox, Thomas, Llewellym, Kelly, Matthews, Louise, Maltby, Jowena, Ibao, Karen, Boulton, Rachel, Jarman, Karen, Baxter, Ashok Sundai Raj, Arif, Moghal, Joanne, White, Suzanne, Barrowcliffe, Mark, Pulletz, Vaarisan, Ganeshalingam, Rosaleen, Baruah, Carole, Boulanger, Helen, Baker, Justin, Woods, Poe Poe Ei, Vongayi, Ogbeide, Paul, Hayden, Jennifer, Hughes, Madhu, Balasubramanian, Armorel, Salberg, Rajnish, Saha, Dagmar, Holmquist, Claire, Derbyshire, Neil, Smith, Elizabeth, Stones, Jane, Ademokun, Monica, Popescu, Maria Schofield Legorburo, Samantha, North, Carole, Brett, Helen, Jaundoo, Jayne, Craig, Simon, Whiteley, Clare, Howcroft, Liz, Wilby, Peter, Delve, David, Shaw, Karen, Williams, Ingeborg, D Welters, Jane, Mcmullen, Stephen, Brett, Leah, Flores, Treiza, Trueman-Dawkins, Mae, Templeton, John, Adams, Catherine, Smith, John, Prowle, Heather, Byers, Andrea, Mcdonnell, Bernd Oliver Rose, Rosie, Reece-Anthony, Luis, Mendes, Marcela, Vizcaychipi, Rhian, Bull, Grace, Lacaden, Eleanor, Santiago, Carlos Castro Delgado, Sarah, Farnell-Ward, Elaine, Thorpe, Justine, Somerville, Anne, Williams, Donna, Cummings, Helen, Derrick, Sarah, Brumwell, Claire, Randell, Nicola, Mccann, Emma, Aves, Gillian, Berry, Tamas, Szakmany, Una, Gunter, Paul, Pulak, Nikki, Sarkar, Kerry, Wright, Vitor, Gomes, Jones, Jo, Ruth, Palfrey, Julie, Camsooksai, Abby, Lewis, Antony, Eneas, Ascanio, Tridente, Louise, Barr, Beverley, Thomas, Emma, Parkin, Daniel, Horner, Christian, Frey, Suzanne, Bench, Rachel, Baumber, Phil, Broadhurst, Matthew, Jackson, Lynne, Williams, Michele, Clark, Jonathan, Paddle, Sarah, Bean, Sarah, Buckley, Christopher, Palfreeman, Sophie, Liu, Nicola, Allison, Ben, Attwood, Penny, Parsons, Victoria, Houghton, Sarah Jane Turner, David, Higgins, Egidija, Bielskute, Nicola, Horrigan, Reni, Jacob, Karen, Habgood, Ahmed, Zaki, Amy, Collins, Jenny, Lord, Charalice, Ramiro, Agnieszka, 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European Society of Intensive Care Medicine (ESICM) Trials Group Collaborators, Muzha, D., Ribas, A.M., Lipovesty, F., Loudet, C., Coyer, F., Eller, P., Mostafa, N., Honoré, P.M., Telleria, V.M., Smajic, J., Nogueira, P.C., Nafees, KMK, Hentchoya, R., Rose, L., Soledad, J., Lin, F., Cardenas, Y., Reyes, A.G., Sustic, A., Mpouzika, M., Vymazal, T., Jensen, H.I., Aguirre-Bermeo, H., Maddison, L., Valta, M., Calvino-Gunther, S., Bloos, F., Adipa, F.E., Koulouras, V., Enamorado, J., Ágoston, Z., Birgisdóttir, H., Gupta, A., Gurjar, M., Kilapong, B., Hashemian, S.M., Martin-Loeches, I., Benbenishty, J., Cortegiani, A., Fletcher, K., Hayashi, Y., Waweru-Siika, W., Abidi, K., Lee, S.M., Hadri, B., Dolgusevs, M., Abillama, F.F., Jovaisa, T., Thix, C., Elhadi, M., Nor, B.M., Ratnam, S., Mazlan, M.Z., Maiyalagan, S., Sánchez-Hurtado, L., Belii, A., Naranpurev, M., Gautam, P., De Lange, D., Parke, R., Ilesanmi, R.E., Shosholcheva, M., Petosic, A., Lind, R., Ffarcsi, M.H., Bogarin, J., Hernandez, A.M., Mikaszewska-Sokolewicz, M., Sousa, B., Tomescu, D., Sandesc, D., Twagirumugabe, T., Gusarov, V., Ebaid, M., Jankovic, R., Slobodianiuk, G., Martonova, A., Knafelj, R., Mer, M., Maseda, E., Panka, B., Schefold, J.C., Joelsson-Alm, E., Trongtrakul, K., Merritt-Charles, L., Besbes, L.O., Dikmen, Y., Zgrzheblovska, L., Fielding, M., Rubulotta, F., Khanna, A.K., Saager, L., von der Osten, I., Greca, A., Cani, A., Xhindi, N., Hyska, G., Pinto, S., Alves, P., Esposito, R., Valgolio, E., Minope, JTS, Abdala, A., Ayala, M., Bravo, S., Bantar, A., Delgado, P., Badariotti, G., Lipovestky, F., Diaz, A., Saul, P., Setten, M., Aucapina, A., Acosta, Y., Gonzalez, V., Camputaro, L., Baccaro, F., Villa, R., Mastantuono, M., Dean, E., Rostello, O.F., Brizuela, P., Bartoli, J.R., Guereschi, M., Quiroga, C., Putruele, S., Villegas, P., Curilen, V., Fernandez, R., Nocheretti, M.G., Escalante, R.G., Loudet, C.I., Fernandez, S., Gonzalez, A.L., Alvarez, G.A., Iglesias, F., Chaparro, S., Zakalik, G., Pagella, G., Baini, M., Campos, P.A., Sabbag, I., Schmukler, A., Fonseca, I.P., Alvarez, G.M., Ramirez, M., Tapia, F., Bascary, C.A., Del Valle Gimenez, G., Bertoletti, F.P., Milioto, E., Bonsignore, PJM, Fernandez, M.A., Smith, J., Chimunda, T., Thompson, L., Maguire, T., Chaboyer, W., Watts, S., Mitchell, M., Powell, M., Lye, I., Parsons, L., Baker, N., Reynolds, C., Thompson, A., Masters, K., Sosnowski, K., Morrison, L., Leslie, G.D., Lakshmanan, R., Tabah, A., Brown, W., McDowell-Skaines, S., McLucas, A., Smith, C., Tallot, M., Jones, S., Barakat-Johnson, M., Leong, T., Butcher, R., Martin, K., Douschan, P., von Lewinski, D., Schmutz, R., Kolussi, U., Salman, F., Ateya, Z., De Decker, K., Van Regenmortel, N., Jans, A., Wijnands, P., Coremans, S., Honore, P.M., De Bels, D., Depuydt, T., Paillet, C., Jacquet, L.M., Swinnen, W., Hannes, F., Mergeay, M., Van de Velde, S., Allaert, S., Hoste, P., Borin, C., Balon, S., Fraipont, V., Biston, P., De Schryver, N., Dugernier, T., Van 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Alvarez, J.D., Arcas, MLB, Gonzalez, JIT, de la Ventana, ABS, Calleja, P.L., Alvarez, R.G., Zamora, P.S., Guerrero, A.O., Cosano, R., Perez-Vacas, J., Campos-Perez, M., Barreiro, E.M., Sanchez, L.C., Diaz, M.G., Jimenez, R., Del Rio Cabajo, L., Muriel, D.S., Alonso, H.F., Fernández, A.W., Piñan, I.S., Albaiceta, G.M., Fernandez, MCI, Abos, FJS, Monedero, P., Chueca, R.M., Aguirre, L.G., Manosa, S.C., Luque, C.P., Calpe, N., Losilla, M.R., Fores, M.T., Farre, O., Fernandez, O., Del Rosario Villar Redondo, M., Arteta Arteta, D.S., Sanchez, MAH, Espinosa, C.P., Reyes, L.M., Domenech, L.C., Guillén, C.V., Alvarez, J.T., Del Cotillo, M., Barrueco-Francioni, J.E., Conde, B.B., Blanco, MPS, Blasco, M.L., Clement, A.I., Hurtado, C., Sanz, L.C., Perez-Torres, D., Prol-Silva, E., Pereira, J., González, I.A., Cano, A.E., Nuñez, C.R., Fernadez, I.L., Fernandez, AAM, Del Bosque Diez, R., Hilario, B., Zalba-Etayo, B., Pascual-Bielsa, A., Banwarie, P., Nahar, D., van Axel, A., Boedjawan, N.N., 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P., Hughes J., Balasubramanian M., Salberg A., Saha R., Holmquist D., Derbyshire C., Smith N., Stones E., Ademokun J., Legorburo M.S., North S., Brett C., Jaundoo H., Craig J., Whiteley S., Howcroft C., Wilby L., Delve P., Shaw D., Williams K., Welters I.D., McMullen J., Brett S., Flores L., Trueman-Dawkins T., Templeton M., Adams J., Prowle J., Byers H., McDonnell A., Rose B.O., Reece-Anthony R., Mendes L., Vizcaychipi M., Bull R., Lacaden G., Santiago E., Delgado C.C., Farnell-Ward S., Thorpe E., Somerville J., Williams A., Cummings D., Derrick H., Brumwell S., Randell C., McCann N., Aves E., Berry G., Szakmany T., Gunter U., Pulak P., Sarkar N., Wright K., Gomes V., Jones J., Palfrey R., Camsooksai J., Lewis A., Eneas A., Tridente A., Barr L., Thomas B., Parkin E., Horner D., Frey C., Bench S., Baumber R., Broadhurst P., Jackson M., Williams L., Clark M., Paddle J., Bean S., Buckley S., Palfreeman C., Liu S., Allison N., Attwood B., Parsons P., Houghton V., Turner S.J., Higgins D., Bielskute E., Horrigan N., Jacob R., Habgood K., Zaki A., Collins A., Lord J., Ramiro C., Kubisz-Pudelko A., Kotze M., Williams H., Iovenko I., Tsarev A., Briva A., Mendez G., Napolitano L., Teig M., Rodriguez G.E., Ben-Jacob T., Potestio C., Eng T., Mahanes D., Khanna A., Duggal A., Nananmori M., Lois M., Karamchandani K., Bealer C., Barefield C., Terry D., Fivecoat P., Idowu O., Cata J., Clesi T., Peterson J., Hatton K., Dhaliwal J., Mueller D., Tao J., Eltorai A.S., Pastores S.M., Remor N., Salazar J., Barkas D., Joffe A., Barnes C., Sona C., Schallom M., Short J., Lorenzo J., Von Der Osten I., Borkowska M., Demarre L., Pleitinckx V., Xing C., Debue A.-S., Goller S., Larina E., Labeau, S. O., Blackwood, B., Brett, S. J., Deschepper, M., Francois, G., Honore, P. M., Khanna, A. K., Williams, G., Blot, S. I., Ribas, A. M., Telleria, V. M., Nogueira, P. C., Nafees, K. M. K., Reyes, A. G., Jensen, H. I., Adipa, F. E., Agoston, Z., Hashemian, S. M., Lee, S. -M., Abillama, F. F., Nor, B. M., Mazlan, M. Z., Sanchez-Hurtado, L., De lange, D., Ilesanmi, R. E., Ffarcsi, M. H., Hernandez, A. M., Schefold, J. C., Besbes, L. O., Minope, J. T. S., Rostello, O. F., Bartoli, J. R., Nocheretti, M. G., Escalante, R. G., Loudet, C. I., Gonzalez, A. L., Alvarez, G. A., Campos, P. A., Fonseca, I. P., Alvarez, G. M., Bascary, C. A., del Valle Gimenez, G., Bertoletti, F. P., Bonsignore, P. J. M., Fernandez, M. A., Leslie, G. D., Mclucas, A., Jacquet, L. -M., de Almeida, A. O., Jorge, S. A., Schmidt, R. C., Garcia, P. C., Ronchini, A. L. V., Manap, N. B. A., Laizner, A. M., Mcquirter, M., Kampayana, B. S., Sepulveda, M. I., Zamorano, M. J. F., Zhao, R. H., Hu, L. P., Jiao, Q. F., Wang, H. Y., Xia, C. J., Insu, L., Zhu, J. Y., Zhu, J. F., Huang, R. F., Wang, L. L., Song, J. H., Liu, X. M., Li, Z. S., Li, L. C., Zeng, J. M., Hu, X. C., Wang, R. X., Tak, P. S., Ho, S. W., Jiang, Q. X., Huang, L. P., Liu, X. L., Jiang, J. H., Gong, Y. Y., Lei, D. H., Bi, A. P., Zhao, H. M., Cao, Z. Q., Wu, S. F., Tian, X. F., Feng, Z. X., Liu, X. Z., Jiang, Z. X., Wang, G. X., Hu, R. L., Li, X. Q., Yu, Z. J., Yang, Y. X., Gama, L. M. S., Hernandez, J. S., Ochoa, M. -E., Reyes, A. J. G., Filipovic-Grcic, I., Vukovic, A., Pecenkovic, S., Suput, A., Radivojevic, R. C., Culjak, H., Adam, V. N., Pedersen, K. R., Kjaergard, I. E., Kodal, A. M., Hansen, T. C. B., Pedersen, A. S. B., Thomsen, T. D., Frandsen, T. M., Bliksted, I. A., Tamayo, L. M., Tutillo, D. R. M., Hurtado, C. V., Garcia, M. F., Kutimets, M., Lofqvist, C., Sakki, J. -K., Valta, M. A., Plantefeve, G., Deserts, M. D., Gunther, S. C., Timsit, J. -F., Farkas, J. -C., Bosl, K., Schuppel, S., Stubner, A., Osei, I. P., Kusi-Appiah, A. -C., Yakubu, Y. H., Patsiou, E. -C., Stalika, K. M. M., Enamorado, J. E., Jonasdottir, R. J., Lestari, M. I., Finn, D. O. C. R., Mcpherson, S., Ghioldi, D. M., Bruno, A. V., Maggiore, S. M., Volta, C. A., Taibi, M. R., Tranello, F. P., Giusti, G. D., Martin, M. A., Correia, M. C., Kim, J. H., Kim, K. C., Bae, J. -M., Park, S. Y., Park, T. S., Lee, H. B., Kim, S. C., Chee, H. K., Huh, J. W., Sim, Y. S., Ahn, J. -J., Kang, B. J., Lee, W. -Y., Lee, S. J., Feghaly, M. E., Belkhair, W. A., Tababa, O. W. E., Alkhumsi, S. I. R., Alshrif, A. I., Aboufray, A. A., Triki, A. R., Zahra, H. B., Al-Alawi, M. M. S., Ghula, M. A. A., Bahrin, L. K. K., Deva, S. R., Rahim, A. H. A., Hassan, W. N. W., Ismail, W. N. W., Ali, M. N., Khoo, T. M., Samat, N. M., Tong, J. M. G., Adib, N. A. N., Nor, M. B. M., Sulaiman, S. R., Foong, K. W., Hua, N. P., Zermeno, J. M., Nava, C. L. L., Nandyelly, S. J. R., Sanchez-Hurtado, L. A., Nava, L. P. A., Herrera, J. G., de Anda, G. F. V., Namendys-Silva, S. A., Romero-Gonzalez, J. P., Sosa, M. A., de Molina Serrano, J. I. R., Iburrigarro, S. R., Padilla, N. R. C., Pineda, A. A. V., Villafuerte, M. V. E., Herrera, M. O. G., Subedi, N. B., Pathak, S. D., Vermeijden, J. W., Gerritsen, R. T., Fijen, J. -W., Adejumo, P. O., Sankey, B. J., Olsen, B. F., Jensen, K. D., Johansen, B. F., Finnstrom, I. J., Skorstad, E. M., Lunde, G. A., Akselsen, G. R., Monstad, K. R., Hogvall, L., Malmin, S. K., Andersen, M. H., Hargott, R. F., de Jesus Ortiz, A., Cabral, D. M. B., Rivas, J. C., Moreira, M. L., Ellazar, C. G., Cerezo, F. D., Palo, J. E., Aperocho, C. A. J., Figueiredo, M. F., Pinheiro, C. M., Rita, C. S., Feranandes, A. M., Pinto, V. M. V., Bispo, B. M., Lima, A., Alsheikhly, A. S., Guran, C. T., Filipescu, D. C., Scutariu, M. A., Ebaid, M. S., Velickovic, D., Rajkovic, M., Stanojevic, M., Turcan, A., Lancaricova, D., Yeni, N. P., Syed, M. R., Navarro, J. A., De Pablo, A. M., Llinas, A. A., Lajara, M. A. G., Nieto, M. V., Pena, J. M. G., Gorgolas, M. C., Isasi, M. A., Salva-Costa, V., Garzon-Tovar, C., Olivares, P. G., de Ceballos, J. P. G., Polo, A. B. C., del Mar Diaz Salcedo, M., Alvarez, J. D., Arcas, M. L. B., Gonzalez, J. I. T., de la Ventana, A. B. S., Calleja, P. L. -A., Alvarez, R. G., Zamora, P. S., Guerrero, A. O., Barreiro, E. M., Sanchez, L. C., Diaz, M. G., Muriel, D. S., Alonso, H. F., Fernandez, A. W., Pinan, I. S., Albaiceta, G. M., Fernandez, M. C. I., Abos, F. J. S., Chueca, R. M., Aguirre, L. G., Manosa, S. C., Luque, C. P., Losilla, M. R., Fores, M. T., del Rosario Villar Redondo, M., Arteta Arteta, D. S., Sanchez, M. A. H., Espinosa, C. P., Reyes, L. M., Domenech, L. C., Guillen, C. V., Alvarez, J. T., del Cotillo, M., Barrueco-Francioni, J. E., Conde, B. B., Blanco, M. P. S., Blasco, M. L., Clement, A. I., Sanz, L. C., Gonzalez, I. A., Cano, A. E., Nunez, C. R., Fernadez, I. L., Fernandez, A. A. M., Boedjawan, N. N., Jansson, E. B., Malvemyr, A. -S., Lof, G., Spangfors, M., Lagerhall, C., Akerman, E., Hellkvist, V. H., Larsson, I. -M., Jong, M. L., Hsu, M. Y., Chang, S. C., Mebazaa, M. S., Elhechmi, Y. Z., Kuscu, O. O., Dal, H. C., Calili, D. K., Izdes, S., Gumus, A., Tasdemir, B., Kagnici, A., Ay, S. A., Balbay, A. O., Ozserezli, B., Senturk, E., Serin, S. O., Gul, F., Cinel, I., Undar, H. N., Bayraktar, Y. S., Celik, J. B., Tokur, M. E., Aydin, D. T., Yildiz, I., Ozcan, B., Akdag, D., Unlu, N., Reyes, P. E., Ahmad, F. K. E., Smiley, K. A., Miller, M. T., Antonio, M. G. S., Qawasmeh, K. A., Shawish, S. A., Groba, C. B., Raj, A. S., Ei, P. P., Legorburo, M. S., Welters, I. D., Mcmullen, J., Mcdonnell, A., Rose, B. O., Delgado, C. C., Mccann, N., Turner, S. J., Rodriguez, G. E., Eltorai, A. S., Pastores, S. M., Demarre, L., and Debue, A. -S.
- Subjects
Male ,Original ,medicine.medical_treatment ,artificial ,Critical Care and Intensive Care Medicine ,Medical and Health Sciences ,Pressure ulcer ,law.invention ,Decubitus epidemiology ,ICU ,Morbidity ,Mortality ,Outcome ,Pressure injury ,Risk factors ,Adult ,Aged ,Hospital Mortality ,Humans ,Patient Discharge ,Prevalence ,Risk Factors ,Intensive Care Units ,Respiration, Artificial ,0302 clinical medicine ,decubitus epidemiology ,pressure injury ,pressure ulcer ,outcome ,risk factors ,morbidity ,mortality ,law ,Medicine and Health Sciences ,adults ,Medicine ,Simplified Acute Physiology Score ,icu ,ziekenhuissterfte ,Immunodeficiency ,intensive care ,European Society of Intensive Care Medicine (ESICM) Trials Group Collaborators ,mannen ,volwassenen ,COST ,Intensive care unit ,STATE ,ULCERS ,Underweight ,medicine.symptom ,Life Sciences & Biomedicine ,Human ,medicine.medical_specialty ,risicofactoren ,Decubitus epidemiology, ICU, Pressure injury, Pressure ulcer, Outcome, Risk factors, Morbidity, Mortality ,pressure injuries ,Intensive Care Unit ,prevalentie ,NO ,1117 Public Health and Health Services ,DecubICUs Study Team ,03 medical and health sciences ,Critical Care Medicine ,Anesthesiology ,General & Internal Medicine ,Health Sciences ,ouderen ,Mechanical ventilation ,Science & Technology ,business.industry ,decubitus ,Risk Factor ,030208 emergency & critical care medicine ,1103 Clinical Sciences ,Odds ratio ,medicine.disease ,Emergency & Critical Care Medicine ,Confidence interval ,030228 respiratory system ,Emergency medicine ,kunstmatige ademhaling ,RISK-FACTORS ,business ,respiration - Abstract
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347, Funder: Flemish Society for Critical Care Nurses, Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score < 19, ICU stay > 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat.
- Published
- 2021
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28. Camel milk whey powder formulated using thermal (spray-drying process) and non-thermal (ultrasonication) processing methods: Effect on physicochemical, technological, and functional properties.
- Author
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Al-Thaibani A, Mostafa H, Al Alawi M, Sboui A, Hamed F, Mudgil P, and Maqsood S
- Abstract
Whey protein concentrates (WPCs) are gaining importance as a functional ingredient due to their high technological and functional properties and their diverse application in the food industry. In this study, Camel milk whey (CW) was separated from skimmed camel milk, then either spray-dried (SD) at 170, 185 and 200 °C, or treated by ultrasonication (US) (20 kHz) for 5, 10 and 15 min followed by freeze-drying to obtain camel milk whey powder (CWP). The structural analysis of CWP was carried out by Fourier-Transform Infrared Spectroscopy (FTIR) and X-Ray Diffraction (XRD) which showed no significant difference in the functional groups profile of US samples compared to control and SD samples. US samples showed some degree of crystallinity that was comparable to the control samples, while SD samples exhibited very low degree of crystallinity. The surface morphology, particle size, and surface charge of CWP were evaluated using scanning electron microscopy (SEM) and Zetasizer. The lowest particle size of 215.1 nm with surface charge of -21.6 mv was observed in SD-185 WPC. Moreover, SD samples revealed whiter color compared to the US-treated samples which were having lower L* values (P < 0.05). US-15 sample exhibited high protein solubility (100 %), whereas the SD-200 sample showed reduced solubility (92.7 %). Improvement in the emulsifying activity of CWP samples was observed after SD and US, with highest emulsifying activity index (EAI) values of 143.75 m
2 /g and 143.11 m2 /g were reported for SD-185 and US-15 CWP samples, respectively. To conclude, SD and US were found to improve the physico-chemical, technological, and functional properties of CWP, and thus can be utilized as a promising strategy to preserve and enhance the technofunctional properties of CWP., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.)- Published
- 2024
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29. Callus induction, shoot regeneration, and conservation of in vitro grown date palm (Phoenix dactylifera).
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Shahrour WG, Shatnawi MA, Shibli RA, Al-Alawi M, Abubaker SM, Majdalawi M, and Alkawaldeh AK
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- Culture Media, Plant Growth Regulators pharmacology, Cryopreservation, Tissue Culture Techniques, Phoeniceae physiology, Phoeniceae drug effects, Regeneration physiology, Regeneration drug effects, Plant Shoots physiology, Plant Shoots growth & development, Plant Shoots drug effects
- Abstract
Date palm (Phoenix dactylifera( cv. Medjool is a significant plant, grown in Jordan. In vitro propagation gives operative resources for the significant propagation of date palms. Maximum callus induction was achieved from MS media supplemented with benzyl amino purine (BA) and naphthalene acetic acid (NAA). The highest plant regeneration was recorded on MS medium supplemented with dichlorophenoxyacetic acid (2,4-D) at 3.0 mg/L, and BA at 2.0 mg/L. A significant positive impact on shoot formation was recorded on MS medium supplemented with 1.0 mg/L BA with 0.5 to 1.5 mg/L NAA in both liquid and solid MS medium. To maintain survival and regrowth capacity, sucrose could be used for medium-term conservation at lower concentrations (0.1 - 0.2 M). In addition, sorbitol might be used at 0.1 M to maintain the quality of explants. The vitrification technique for long-term preservation was experimented. Embryogenic callus was used as explants for conservation. The survival as well as regrowth percentages of non-cryopreserved and cryopreserved tissue cultures were affected by their duration of treatment with the vitrification solution plant vitrification solution 2 (PVS2) and modified plant vitrification solution 2 (MPVS2). Results showed that using PVS2 for 60 minutes for cryopreserved calli was more effective than other treatments. After storage in liquid nitrogen, the highest survival rate (65%) and regrowth rate (40%) were achieved.
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- 2024
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30. Colorectal Cancer Detection during a Screening Awareness Campaign in a High-Risk Region in Oman.
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Al Mutaani J, Al Hasani B, Al Hattali S, Al Oraimi M, Al Alawi N, Kumar S, Al Sadi K, Al Alawi S, Al Harbi M, Al Faraji A, Al Rajhi A, Al Jaffari M, Al Jaffari S, Al Alawi M, Al Suri M, Al Satmi F, Al Saadi M, Al Rottali B, Al Wihabi F, Hmissa S, Ouahchi I, and Missaoui N
- Subjects
- Humans, Male, Middle Aged, Female, Oman epidemiology, Adult, Risk Factors, Mass Screening methods, Health Knowledge, Attitudes, Practice, Prognosis, Aged, Follow-Up Studies, Surveys and Questionnaires, Health Promotion methods, Colorectal Neoplasms diagnosis, Colorectal Neoplasms epidemiology, Colorectal Neoplasms prevention & control, Early Detection of Cancer methods, Early Detection of Cancer statistics & numerical data, Occult Blood, Colonoscopy statistics & numerical data
- Abstract
Introduction: Colorectal cancer (CRC) constitutes the third most frequently diagnosed cancer in Oman. This study report the result of a community based screening campaign to promote the early detection and explore the associated risk factors of CRC amongst Omani population., Methods: We launched a colorectal cancer awareness campaign in Oman's South Ash Sharqiyah Governorate between January and March, 2023. We conducted a stratified random study including 688 adult Omani participants aged over 40 years old. Local Health Centers collected the questionnaire forms. Fecal occult blood tests (FOBTs) were carried out at Local Health Centers; while medical professionals performed the colonoscopy examination in Sur University Hospital., Results: Overall, the screening response rate was 68.8%. The data indicated that 8.1% of the total sample yielded positive FOBTs; of whom, 85.7% were aged 40-59 years old and 67.9% were obese or overweight. Abnormal colonoscopy was reported in 7 participants. One participant had a confirmed CRC of stage I., Conclusion: Screening and early detection campaign can have effect and increase the rate of early detection among population in Oman.
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- 2024
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31. Understanding physician burnout in Oman: current status, cultural influences and future directions.
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Al Alawi M and Al Ghailani A
- Abstract
Amidst the current global surge in physician burnout, a compelling need arises for precisely targeted research and interventions that cater to specific contexts, illuminating a path towards professional well-being. This brief communication analyses recent studies on physician burnout in Oman, critically evaluating the findings, cultural factors, methodological limitations and future growth opportunities. Distinct elements of Omani culture, encompassing attitudes towards mental illness, gender roles and patient expectations, can distinctly influence how burnout presents in this population. Advanced mixed-methods research integrating cultural insights, biomarkers and longitudinal tracking is needed to characterise burnout in Omani physicians. The findings can play a significant role in developing comprehensive interventions, at both a systemic and an individual level, that promote well-being of physicians while specifically aligning with the cultural values of Oman., Competing Interests: None., (© The Author(s) 2024.)
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- 2024
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32. Telephone-based telepsychiatry consultations: a qualitative exploration of psychiatrists' experiences in Oman.
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Al-Mahrouqi T, Al-Alawi K, Al-Sabahi F, Al-Harrasi A, Al-Sinawi H, Al-Balushi N, Al-Shekaili M, and Al-Alawi M
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- Child, Adolescent, Humans, Psychiatrists, Oman, Referral and Consultation, Telephone, Psychiatry, Telemedicine
- Abstract
Objectives: The utilisation of tele-mental health services has the potential to address challenges in mental health services within the Eastern Mediterranean Region. However, the adoption of tele-mental health in Oman remains limited. Therefore, this study aimed to explore the experiences of psychiatrists with telephone consultations, offering valuable insights to advance the field of telepsychiatry., Design: This is a qualitative exploratory study. The analysis of the data involved the application of manifest content analysis., Setting: The semi-structured interviews were conducted with the psychiatrists at Al Masarra Hospital., Participants: A total of 10 semi-structured interviews were conducted., Results: The study reveals that psychiatrists encounter communication challenges in telephone consultations, such as the absence of visual cues, confirming patient identity, conducting comprehensive assessments and effectively communicating with younger patients who may lack developed social skills or patients with specific health conditions. Infrastructure limitations, such as outdated medical records, lack of electronic prescriptions and limited availability of child/adolescent psychiatric medications, further restrict the effectiveness of telepsychiatry consultations. In contrast, telephone appointments offer convenience and flexibility for psychiatrists, allowing them to manage non-clinical responsibilities and provide focused consultations tailored to individual needs. In addition, it benefits patients by improving appointment adherence, diminishing stigma and financial savings compared with in-person consultations., Conclusions: Tele-mental health has emerged as a promising avenue for enhancing mental healthcare services in Oman. Addressing psychiatrists' challenges is crucial to further developing and strengthening these services., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2024
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33. The Seroprevalence of Hepatitis C Virus (HCV) in Hemodialysis Patients in Oman: A National Cross-Sectional Study.
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Al Shukri I, Al Wahaibi A, Al Kindi H, Al-Maimani Y, Al Maani A, Alqayoudhi A, Methew MC, Pradeesh J, Al Abrawi R, Debs A, Mansoor N, AlRahbi A, Al Balushi W, Alharrasi M, Al Mamari B, Soliman MF, Alsenaidi A, Al Alawi M, Al Ismaili O, Al-Abri S, and Al-Jardani A
- Subjects
- Humans, Cross-Sectional Studies, Seroepidemiologic Studies, Oman epidemiology, Renal Dialysis, Risk Factors, Prevalence, RNA, Hepacivirus genetics, Hepatitis C epidemiology
- Abstract
Background: HCV infection in hemodialysis units is a significant cause of morbidity and mortality. The risk of HCV infection among dialysis patients is higher compared to the general population due to high potential blood exposures in hemodialysis settings. This study aims to assess the national HCV seroprevalence in selected dialysis units and to determine the risk factors for acquiring HCV infection., Methods: This cross-sectional study was conducted from 1 January to 31 March 2021. A total of 734 patients from 11 hemodialysis centers in Oman were included. Samples were tested simultaneously for HCV antibodies and HCV RNA. HCV genotyping was determined in all viremic patients. Demographic and hemodialysis center related data were gathered and their association with the positive HCV serology were explored using univariate and multivariate logistic regression analysis., Results: Out of 800 patients selected from 11 dialysis units for the study, 734 patients (91.8%) were included. The overall seroprevalence of HCV infection among hemodialysis patients was 5.6%. (41/734). HCV RNA was detected in 31.7% (13/41) of seropositive hemodialysis patients. The most common genotype was subtype 1a, followed by subtype 3. Variables associated with high HCV prevalence were family history of HCV and duration of dialysis., Conclusion: The prevalence of infection within hemodialysis patients in Oman has significantly decreased but remained higher than the general population. Continuous monitoring and follow-up, including periodic serosurvey and linkage to care and treatment are recommended. Additionally, practice audits are recommended for identifying gaps and ensuring sustainability of best practices and further improvement., (© 2023. The Author(s).)
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- 2023
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34. Near-miss accidents data analysis and knowledge dissemination in water construction projects in Oman.
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Al Shaaili M, Al Alawi M, Ekyalimpa R, Al Mawli B, Al-Mamun A, and Al Shahri M
- Abstract
The strategic role of near-miss data in safety management is undeniably vital. This data provides early warnings of potential accidents, thus serving as a proactive tool for recognizing weak points in safety management and preventing disasters. Reinforcing this premise, an investigation was launched to delve into the classification and analysis of near-miss accident data, aiming to augment safety prevention knowledge in the Nama Water Services (NWS) Company. The study engaged in comprehensive activities, including gathering near-miss reports, engaging with HSE personnel, formulating a standardized near-miss data form, and analyzing the collected data. Additionally, it proposed a structured guideline for identifying, analyzing, and classifying near-miss incidents, hinging on various parameters like types of hazards, operations, time of occurrence, and project segments. The findings highlighted that the construction projects involving pipelines and reservoirs experienced the most incidents, predominantly occurring during weekday mornings and afternoons. Major hazards included falls from scaffolds, falls within trenches, and lax housekeeping. Most notably, the operations most frequently associated with near-miss incidents were excavation, lifting, and loading. A deep dive into the root causes revealed that poor supervision, inadequacies in the safe work system, insufficient control measures, and inadequate training were the primary culprits. Furthermore, the study indicated that workers and equipment bore the brunt of these incidents., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 The Authors.)
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- 2023
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35. Dexmedetomidine in the Treatment of Depression: An Up-to-date Narrative Review.
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Al-Mahrouqi T, Al Alawi M, and Freire RC
- Abstract
Depressive disorders (DD) are common, and their prevalence is expected to rise over the next decade. Depressive disorders are linked to significant morbidity and mortality. The clinical conundrum of depressive disorders lies in the heterogeneity of their phenomenology and etiology. Further, the currently available antidepressants have several limitations, including a delayed onset of action, limited efficacy, and an unfavorable side effect profile. In this review, Dexmedetomidine (DEX), a highly selective and potent α2-adrenergic receptor (α2-AR) agonist, is proposed as a potentially novel antidepressant with multiple mechanisms of action targeting various depression pathophysiological processes. These mechanisms include modulation of the noradrenergic system, regulation of neuroinflammation and oxidative stress, influence on the Brain-Derived Neurotrophic Factor (BDNF) levels, and modulation of neurotransmitter systems, such as glutamate. The review begins with an introduction before moving on to a discussion of DEX's pharmacological features. The pathophysiological and phenomenological targets of DD are also explored, along with the review of the existing preclinical and clinical evidence for DEX's putative anti-depressant effects. Finally, the review ends by presenting the pertinent conclusions and future directions., Competing Interests: Rafael Freire is the Editorial Advisory Board member of the journal Clinical Practice & Epidemiology in Mental Health., (© 2023 Al-Mahrouqi et al.)
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- 2023
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36. The differential mediating roles of resilience in the relationship between meaningful living and stress among college students during the COVID-19 pandemic.
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Al-Mahrouqi T, Chan MF, Al-Mukhaini M, Al Shehi M, Al-Huseini S, Jahan F, Al Balushi N, Panchatcharam SM, and Al Alawi M
- Subjects
- Humans, Cross-Sectional Studies, Pandemics, Knowledge, Students, COVID-19 epidemiology
- Abstract
The current literature, mostly Euro-American based, indicates that the presence of meaning in life (MIL) improves resilience and lowers stress. However, the differential mediating roles of resilience in the relationship between the search for and presence of MIL, and stress have not been explored. This study aimed to investigate the differential mediating roles of resilience in the relationship between the presence of and search for MIL, and stress among Omani college students amid the COVID-19 pandemic. This cross-sectional study consisted of the Brief Resilience Scale, Perceived Stress Scale 4, and Meaning in Life Questionnaire, as well as socio-demographic questions. A path analysis model was used to examine the hypothesis. A total of 970 Omani college students responded to the questionnaire. Findings indicate that searching for MIL was significantly associated with a high level of stress directly (β = 0.023; p < 0.001) and indirectly, through a negative effect on resilience (β = 0.006; p < 0.001). Conversely, the presence of MIL was significantly associated with a decreased level of stress directly (β = - 0.045; p < 0.001) and indirectly via a positive effect on resilience (β = - 0.151; p < 0.001). In keeping with the proposed hypothesis, this study contributes to the current knowledge, by extrapolating the effect of searching for MIL on resilience and stress, and culturally re-contextualizing MIL research. University counseling centers could adopt meaning-based strategies to mitigate stress by promoting meaningful living and resilience., (© 2023. The Author(s).)
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- 2023
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37. Contribution of outdoor noise-induced health risk in schools located in urbanized arid country.
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Amoatey P, Al-Harthy I, Amankona D, Douban S, Izady A, Chen M, Al-Jabri K, and Al-Alawi M
- Subjects
- Female, Humans, Surveys and Questionnaires, Schools, Oman, Environmental Exposure, Aircraft, Noise, Transportation
- Abstract
Ambient noise pollution is deemed as one of the major growing public health issues, especially in developing countries. Therefore, it is crucial to assess the impact of noise pollution on public health. The aim of this study is to investigate the health risk of noise exposure levels in three schools: Kaab Bin Zeyd of Basic Education (school A), Hail Al-Awamour Girls school (school B), and Al-Fikr School (school C) in Muscat, Oman. The study employed a survey of 300 students, dose-response models, and regression models to quantify health risk and to determine the relationship between noise levels and perceived noise annoyance sources. The study found average noise levels (L
Aeq ) of school A (70.03±8.21 dBA), school B (69.54±7.75 dBA), and school C (55.95± 5.67 dBA) to be higher than WHO's outdoor schools environment standard of 55 dBA and European (EN16798-1) classroom's critical limits of 30-34 dBA. Most of the students from schools A (30.9%), B (33.3%), and C (63%) have reported noise produced from traffic as extremely annoyed compared to aircraft of 15.4%, 11.5%, and 27.2%, respectively. Regression analysis shows that perceived traffic noise was strongly correlated with LAeq in school A (R2 =0.481), B (R2 =0.121), and C (R2 = 0.132) when compared with other subjective noise types. The health risk assessment results show that the percentage of highly annoyed (%HA) was higher in school A (15.2%) and school B (14.95%) than in school C (8.18%). The estimated highly sleep disturbed (%HSD) based on mean noise levels were almost the same in schools A (15.62%) and B (15.19%) but far higher compared to school C (6.01%). However, there was an association between the mean noise exposure levels and the risk of developing ischemic heart diseases (IHD) in school A (RR= 1.172, 95% CI: 1.020-1.334), school B (RR=1.167, 95% CI: 1.020-1.325), and school C (RR=1.051, 95% CI: 1.006-1.095). Moreover, attributable risk percentage (AR%) for school A (AR% =14.675, 95% CI: 2.028-25.037), school B (AR% =14.310, 95% CI: 1.960-24.528), and school C (AR% = 4.852, 95% CI:0.596-8.742) have shown that a substantial portion of the population could be prevented from developing IHD. It is expected that findings of the study can be applied in other arid regions with sprawl urbanized built environments., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)- Published
- 2023
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38. Predictors and Outcome of Ventriculoperitoneal Shunt Infection: A Retrospective Single-Center Study.
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Abuhadi M, Alghoribi R, Alharbi LA, Barnawi Z, AlQulayti R, Ahmed A, Al-Alawi M, and Baeesa SS
- Abstract
Background: Shunt infection critically affects approximately 8-10% of all inserted shunts, leading to significant morbidity and mortality. This study aimed to assess the clinical and laboratory factors associated with shunt infection and outcomes in patients treated for hydrocephalus. Methods : A retrospective study was performed on patients who underwent ventriculoperitoneal shunt (VPS) surgery for hydrocephalus between January 2015 and June 2018. The primary outcome was the development of shunt infection following VPS surgery. Records were reviewed, and variables were analyzed, including patients' demographics, perioperative laboratory and shunt data, and outcomes. The patients had five years of follow-up from surgery, including a minimum of two years from the onset of VPS infection., Results: A total of 132 shunts were inserted in 103 patients with a mean age of 2 years (range; 2 days to 73 years), and 53.4% were males. Twenty-two patients were suspected of having VPS infection (16.7% per procedure); only six (4.5%) had positive cerebrospinal fluid (CSF) detected organisms. Patients with preoperative hemoglobin, white blood cells, and serum glucose within normal values had a lower shunt infection rate. The pediatric population had an elevated risk of VPS infection, particularly those who underwent surgery at a younger age than 7.5 months, weighed less than 10 Kg, and were associated with myelomeningocele. in addition, a shorter surgery time of less than 82 min, single surgeon, and operating room of fewer than four attendees are associated with lower risk of VPS infection., Conclusion: We emphasize that early identification and modifications of the risk factors can minimize the probability of developing VPS infection and improve patients outcome., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2022, Abuhadi et al.)
- Published
- 2022
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39. Combined endoscopic and radiologic intervention for management of acute perforated peptic ulcer: a randomized controlled trial.
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Negm S, Mohamed H, Shafiq A, AbdelKader T, Ismail A, Yassin M, Mousa B, Abozaid M, Orban YA, Al Alawi M, and Farag A
- Subjects
- Acute Disease, Adult, Humans, Male, Postoperative Complications surgery, Abdominal Abscess, Incisional Hernia surgery, Laparoscopy, Peptic Ulcer Perforation surgery, Renal Insufficiency surgery
- Abstract
Background: Peptic ulcer perforation is a common life-threatening surgical emergency. Graham omental patch is performed for plugging of perforated peptic ulcer. Many endoscopic methods have been used to treat acute perforated peptic ulcer such as over the scope clips, standard endoscopic clips, endoscopic sewing and metallic stents. The main idea in endoscopic management of acute perforated peptic ulcer is early decontamination and decrease sepsis by interventional radiologic drainage., Methods: This is a prospective randomized controlled clinical trial. This study included patients who were developed acute perforated peptic ulcer manifestations and were admitted to our hospital between December 2019 and August 2021. Sample size was 100 patients divided into 2 equal groups. Endoscopic group (EG): included 50 patients who were subjected to endoscopic management. Surgical group (SG): included 50 patients who were subjected to surgical management., Results: One hundred patients were randomized into 2 groups: SG (50) and EG (50). Median age of patients was 36 (range 27:54) and 47 (range 41:50) years-old in SG and EG, respectively. Males constituted 72% and 66% in SG and EG, respectively. Median length of postoperative hospital stay was 1 (range: 1-2) days in EG, while in SG was 7 (range 6-8) days. Postoperative complications in SG patients were 58% in form of fever, pneumonia, leak, abdominal abscess, renal failure and incisional hernia (11%, 5%, 5%, 3%, 2% and 3%, respectively). Postoperative complications in EG patients were 24% in form of fever, pneumonia, leak, abdominal abscess, renal failure and incisional hernia (10%, 0%, 2%, 0%, 0% and 0%, respectively)., Conclusion: Combined endoscopic and interventional radiological drainage can effectively manage acute perforated peptic ulcer without the need for general anesthesia, with short operative time, in high risk surgical patients with low incidence of morbidity & mortality., (© 2022. The Author(s).)
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- 2022
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40. A promising future for tele-mental health in Oman: A qualitative exploration of clients and therapists' experiences.
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Al-Mahrouqi T, Al-Alawi K, Al-Alawi M, Al Balushi N, Al Ghailani A, Al Sabti H, and Al Sinawi H
- Abstract
Objectives: Tele-mental health services can play an important role in overcoming barriers in mental health services in the Eastern Mediterranean Region. However, despite its potential, tele-mental health has not been widely adopted in Oman. This study is an exploratory investigation into the experiences of therapists and their clients in utilizing video-based tele-mental health care during the COVID-19 pandemic., Methods: A total of 19 semistructured qualitative interviews were individually conducted, it included 13 adult clients with mental health conditions who received video-based tele-mental health care and six clinical psychologists who provided video-based tele-mental health care during the COVID-19 pandemic., Results: The clients reported favorable experiences using tele-mental health, with the primary benefits being convenience, easy accessibility to subspecialized care, reduced absenteeism from work with commuting costs, and alleviated mental health stigma. The therapists also expressed experiencing benefits from tele-mental health, such as reduced risk of intrahospital infection, reduced healthcare costs, and the achievement of work-life balance. Primary concerns were related to the lack of public tele-mental health services, lack of specified tele-mental health guidelines, shortage of trained therapists, limited access to high-speed Internet, electronic devices, privacy, and concerns toward the security of telehealth systems in general., Conclusion: Clients and therapists report that tele-mental health offers new opportunities to improve the quality of mental healthcare services in Oman, and that the challenges could be resolved by establishing governmental tele-mental health services along with developing tele-mental health guidelines and implementing local postgraduate clinical psychology programs in universities in Oman., Competing Interests: Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2022.)
- Published
- 2022
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41. Clinical Predictors of Depression among Patients with Inflammatory Bowel Diseases: A Cross-sectional Analytical Study from Oman.
- Author
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Al-Aamri H, Al-Huseini S, Chan MF, Al Saadi A, Al-Sibani N, Al-Dughaishi Z, and Al-Alawi M
- Abstract
Objectives: Many studies suggest that depression is prevalent among patients suffering from inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Both depression and IBD have a significant disease burden. However, these studies have mostly been conducted among European and American populations and there is a paucity of studies from Arab countries. This study aimed to examine the prevalence and predictors of depressive symptoms among adult IBD patients attending a tertiary care hospital in Muscat, Oman., Methods: We conducted a cross-sectional study among a random sample of patients aged ≥ 18 years who attended the gastroenterology clinic at Sultan Qaboos University Hospital, Muscat, Oman, between June 2018 and January 2019. Participants were asked to complete the Patient Health Questionnaire-9, which is used to assess depression, and a sociodemographic survey. Logistic regression analysis was used to identify the independent predictors of depressive symptoms among the study sample. Adjusted odds ratios (aORs) were also reported., Results: This study included 201 participants, with an average age of 36 years. Just over half (51.2%) of participants were female. The mean duration of the patients' IBD diagnosis was 1.9±0.3 years, the majority (n = 174, 86.6%) of the participants had UC, 80.1% (n = 161) of the participants had received steroids, and 5.5% of the sample had a history of a surgical stoma. The medical comorbidities among the participants were cerebrovascular accidents (24.9%), hypertension (24.5%), and diabetes mellitus (23.9%). The prevalence of depressive symptoms was 23.4%. The logistic regression analysis resulted in four independent predictors of depression: being female (OR = 2.090, p = 0.047), history of surgical stoma (OR = 5.737, p < 0.001), comorbid diagnosis of hypertension (OR = 2.846, p = 0.007), and history of a cerebrovascular accident (OR = 2.651, p = 0.011)., Conclusions: Depressive symptoms are prevalent among Omani patients with IBD. Certain clinical factors appeared to increase the risk of depression among this population. The findings of this study fill a gap in the existing literature and call for further work aiming at screening and managing depression among IBD patients., (The OMJ is Published Bimonthly and Copyrighted 2022 by the OMSB.)
- Published
- 2022
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42. Exploring Factors Associated With Depressive Symptoms Among Patients With Chronic Pain: A Cross-Sectional Multicenter Study.
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Al Shukaili M, Al Alawi M, Al Huseini S, Al Shukaili A, Al Muharrami M, Al Abdali M, Al Harthi H, Al Saadi A, Al Balushi R, Al Kasbi F, Al-Fahdi A, Panchatcharam SM, Cucchi A, and Al-Adawi S
- Subjects
- Adult, Cross-Sectional Studies, Depression diagnosis, Female, Humans, Logistic Models, Male, Middle Aged, Patient Health Questionnaire, Severity of Illness Index, United Kingdom epidemiology, Chronic Pain epidemiology, Depression epidemiology
- Abstract
Abstract: This cross-sectional study examined the factors associated with depression among people with chronic pain (PwCP) attending specialized pain clinics in Muscat, Oman. Two-hundred eighty-seven participants were recruited for the study, and univariate analyses were used to investigate the difference between individuals who scored above/below the cutoff points for depressive symptoms. A multiple regression analysis was used to detect the independent predictors. Twenty-six percent of participants scored above the cutoff point. Further analysis indicated that unstable family relationships pre-existing depressive symptoms (odds ratio [OR], 2.86; p = 0.044), a family history of depression (OR, 4.75; p = 0.019), severe pain (OR, 4.21; p < 0.006), having fibromyalgia (OR, 28.29; p = 0.005), and lumbago/truck (OR, 2.41; p = 0.039) were independent predictors of depressive symptoms. This study indicates that one in four patients with chronic pain also presents with depressive symptoms. However, the role of culture needs to be taken into consideration when interpreting these findings and when building on these data., (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2022
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43. Intellectual Profile of Children with Autism Spectrum Disorder: Identification of verbal and nonverbal subscales predicting intelligence quotient.
- Author
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Al-Mamari W, Idris AB, Gabr A, Jalees S, Al-Jabri M, Abdulrahim R, Al-Mujaini A, Islam MM, Al-Alawi M, and Al-Adawi S
- Subjects
- Adolescent, Child, Child, Preschool, Cognition, Female, Humans, Intelligence, Intelligence Tests, Male, Oman, Autism Spectrum Disorder complications, Autism Spectrum Disorder diagnosis
- Abstract
Objectives: This study aimed to explore the intelligence quotient (IQ) profile among children with autism spectrum disorder (ASD) and identify the most important subscales that predict the IQ. The analysis of an intellectual profile with age and gender differentials and the identification of a battery of subscales of intelligence are important for clinical management of ASD among children and for facilitating placement for remedial and educational services., Methods: Data were collected through an exploratory study of 100 children aged between three and 13 years, who were referred to the department of child health and development in Sultan Qaboos University Hospital, a tertiary hospital, in Oman between June 2016 and June 2019., Results: Among the 100 participants of this study, 79% were male, resulting in a male-female ratio of 4:1. The mean of full-scale IQ was found to be 68.6 ± 18.1. Furthermore, the mean of nonverbal IQ (73.5 ± 17.5) was significantly higher than that of verbal IQ (65.5 ± 17.6). Finally, more than half (61%) of the children were observed to have had mild to moderate impairment in their IQ levels., Conclusions: Age and gender showed no significant association with IQ level. The regression analysis identified nonverbal fluid reasoning, nonverbal visual-spatial processing, nonverbal working memory and verbal knowledge as the significant predictors of total IQ. The crucial dimensions of verbal and nonverbal IQ identified in this study can be used to evaluate complicated cases., Competing Interests: CONFLICT OF INTEREST The authors declare no conflicts of interest., (© Copyright 2021, Sultan Qaboos University Medical Journal, All Rights Reserved.)
- Published
- 2021
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44. Development and validation of an instrument to measure physician awareness of bioethics and medical law in Oman.
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Al-Busaidi AS, Ganesh A, Al-Adawi S, Al-Farsi YM, Al-Rawahi MK, Al-Mawali NA, Al-Kharousi NS, Al-Alawi M, and Al-Mujaini AS
- Subjects
- Cross-Sectional Studies, Humans, Oman, Reproducibility of Results, Surveys and Questionnaires, Bioethics, Physicians
- Abstract
Background: A different ethos with respect to the perception of medical ethics prevails in societies in transition such as those in the Arabian Peninsula, which makes it difficult to apply international principles of bioethics in medical practice. This study aimed to develop and psychometrically test an instrument that measures physicians' awareness of bioethics and medical law and their attitudes towards the practice of medical ethics. Additionally, it examined physician correlates influencing the awareness of bioethics., Methods: Following a rigorous review of relevant literature by a panel of experts, a 13-item instrument, the Omani physicians' bioethics and medical law awareness (OBMLA) questionnaire was developed with the aim of assessing physicians' awareness of bioethics and medical law. The study tool's construct validity and internal consistency reliability were examined by exploratory factor analysis (EFA) and Cronbach's alpha. In a cross-sectional study, the questionnaire was distributed among a random sample of 200 physicians at a tertiary hospital in Muscat, Oman. Participant characteristics that may influence awareness of bioethics and medical law were explored., Results: The EFA of the OBMLA questionnaire resulted in three well-loading factors: (1) Physicians' bioethics practice subscale (2) incentive related bioethics subscale and (3) medical law awareness subscale. Internal consistency reliability ranged between Cronbach's α: 0.73-0.8. Of the total 200 participants, 52% reported that teaching medical ethics during medical school was inadequate. The overall mean (standard deviation, SD) of the bioethics awareness score and Omani medical law awareness were 27.6 (3.5) and 10.1 (2.1) respectively. The majority of physicians (73%) reported that they frequently encountered ethical dilemmas in their practice and 24.5% endorsed the view that unethical decisions tended to occur in their practice., Conclusion: The study provides an insight into the practice of bioethics, and the awareness of bioethics and medical law among physicians in a teaching hospital in Oman. The OBMLA questionnaire appears to be a valid and reliable tool to assess a physician's awareness of bioethics and medical law. In this preliminary study, it appears that participants have suboptimal scores on the indices which measure practice and awareness of bioethics and medical law.
- Published
- 2021
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45. Efficacy of a Six-Week-Long Therapist-Guided Online Therapy Versus Self-help Internet-Based Therapy for COVID-19-Induced Anxiety and Depression: Open-label, Pragmatic, Randomized Controlled Trial.
- Author
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Al-Alawi M, McCall RK, Sultan A, Al Balushi N, Al-Mahrouqi T, Al Ghailani A, Al Sabti H, Al-Maniri A, Panchatcharam SM, and Al Sinawi H
- Abstract
Background: The COVID-19 pandemic has led to a notable increase in psychological distress, globally. Oman is no exception to this, with several studies indicating high levels of anxiety and depression among the Omani public. There is a need for adaptive and effective interventions that aim to improve the elevated levels of psychological distress due to the COVID-19 pandemic., Objective: This study aimed to comparatively assess the efficacy of therapist-guided online therapy with that of self-help, internet-based therapy focusing on COVID-19-induced symptoms of anxiety and depression among individuals living in Oman during the COVID-19 pandemic., Methods: This was a 6-week-long pragmatic randomized controlled trial involving 60 participants who were recruited from a study sample surveyed for symptoms of anxiety or depression among the Omani public amid the COVID-19 pandemic. Participants in the intervention group were allocated to receive 1 online session per week for 6 weeks from certified psychotherapists in Oman; these sessions were conducted in Arabic or English. The psychotherapists utilized cognitive behavioral therapy and acceptance and commitment therapy interventions. Participants in the control group received an automatic weekly newsletter via email containing self-help information and tips to cope with distress associated with COVID-19. The information mainly consisted of behavioral tips revolving around the principles of cognitive behavioral therapy and acceptance and commitment therapy. The primary outcome was measured by comparing the change in the mean scores of Patient Health Questionnaire-9 (PHQ-9) and General Anxiety Disorder-7 (GAD-7) scale from the baseline to the end of the study (ie, after 6 sessions) between the two groups. The secondary outcome was to compare the proportions of participants with depression and anxiety between the two groups., Results: Data from 46 participants were analyzed (intervention group n=22, control group n=24). There was no statistical difference in the baseline characteristics between both groups. Analysis of covariance indicated a significant reduction in the GAD-7 scores (F
1,43 =7.307; P=.01) between the two groups after adjusting for baseline scores. GAD-7 scores of participants in the intervention group were considerably more reduced than those of participants in the control group (β=-3.27; P=.01). Moreover, a greater reduction in mean PHQ-9 scores was observed among participants in the intervention group (F1,43 =8.298; P=.006) than those in the control group (β=-4.311; P=.006). Although the levels of anxiety and depression reduced in both study groups, the reduction was higher in the intervention group (P=.049) than in the control group (P=.02)., Conclusions: This study provides preliminary evidence to support the efficacy of online therapy for improving the symptoms of anxiety and depression during the COVID-19 crisis in Oman. Therapist-guided online therapy was found to be superior to self-help, internet-based therapy; however, both therapies could be considered as viable options., Trial Registration: ClinicalTrials.gov NCT04378257; https://clinicaltrials.gov/ct2/show/NCT04378257., (©Mohammed Al-Alawi, Roopa K McCall, Alya Sultan, Naser Al Balushi, Tamadhir Al-Mahrouqi, Abdullah Al Ghailani, Hilal Al Sabti, Abdullah Al-Maniri, Sathiya M Panchatcharam, Hamed Al Sinawi. Originally published in JMIR Mental Health (http://mental.jmir.org), 12.02.2021.)- Published
- 2021
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46. Predictors of psychological distress among the public in Oman amid coronavirus disease 2019 pandemic: a cross-sectional analytical study.
- Author
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Sinawi HA, Al Balushi N, Al-Mahrouqi T, Al Ghailani A, McCall RK, Sultan A, Al Sabti H, Al Maniri A, Murthi Panchatcharam S, and Al-Alawi M
- Subjects
- Adult, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Oman epidemiology, Prevalence, Adaptation, Psychological, Anxiety epidemiology, Anxiety Disorders epidemiology, COVID-19, Psychological Distress, Stress, Psychological epidemiology
- Abstract
Coronavirus disease 2019 (COVID-19) is a global, virulent pandemic disease that emerged in December 2019, with both short- and long-term psychological repercussions being inevitable. This study aimed to investigate the prevalence and predictors of psychological distress, defined by the presence of either depression or anxiety, among the public in Oman during the COVID-19 pandemic. This was a web-based, cross-sectional study conducted using governmental and private institutional e-mail systems and social media platforms. Anxiety and depression were assessed using both the Generalized Anxiety Disorder-7 Scale and the Patient Health Questionnaire-9. Logistic regression analysis was used to assess the independent predictors. There were a total of 1538 participants in this study (75% female). The prevalence of psychological distress was 30%. Being female, having financial instability, being treated for mental illness and self-medication for coping with stress were independent predictors of psychological distress among the study sample (Odds ratio [OR] = 1.69, confidence interval [CI] = 1.24-2.29; OR = 2.05, CI = 1.54-2.74; OR = 5.35, CI = 3.50-8.18; OR = 7.23, CI = 3.06-17.09, respectively). The results from this study will help public health officials in Oman to plan for and mitigate psychological repercussions of the current and future pandemics.
- Published
- 2021
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47. Prevalence of Depression among Oman Medical Specialty Board Residents.
- Author
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Al-Alawi M
- Published
- 2020
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48. Industrial pipelines data generator.
- Author
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Al-Alawi M, Bouferguene A, and Mohamed Y
- Abstract
The construction of industrial projects involves fabricating and installing massive quantities of pipelines. The design data of pipelines is complex, usually unique for each project and not easily available to researchers and the public for confidentiality reasons. As a result, an industrial pipelines data generator able to realistically simulate pipelines structures will lessen the dependence on real-life data. This article describes an industrial pipelines data generator that was developed using topological and physical properties of pipelines from real industrial projects. This generator can simulate the properties (the type of component, length, diameter, running direction, and the connectivity relationships between components) of real industrial pipelines. Its application in construction engineering and management research, more specifically in the experimental analysis of an optimization algorithm, was described by the authors in previous work [1]. The data generator can be used to develop benchmark problem instances for optimization problems and for simulation studies of construction operations in industrial projects., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships which have, or could be perceived to have, influenced the work reported in this article., (© 2020 The Author(s).)
- Published
- 2020
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49. The potential anti-depressant properties of dexmedetomidine infusion: a review of mechanistic, preclinical, and clinical evidence.
- Author
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Al-Alawi M, Brietzke E, Carvalhal A, and Soares CN
- Subjects
- Dexmedetomidine administration & dosage, Drug Resistance drug effects, Humans, Signal Transduction drug effects, Antidepressive Agents therapeutic use, Depression drug therapy, Depressive Disorder, Major drug therapy, Dexmedetomidine therapeutic use
- Abstract
Major depressive disorder (MDD) is a highly prevalent and disabling condition for which the currently available treatments are not fully effective. Existing unmet needs include rapid onset of action and optimal management of concurrent agitation. Dexmedetomidine (DEX) is a selective and potent α2-adrenergic receptor (α2-AR) agonist, with unique pharmacokinetic and pharmacodynamic properties. In this review, we discuss pre-clinical and clinical studies which focused on DEX in the context of its putative antidepressant effects for the management of MDD. Preliminary data support DEX as an antidepressant with fast onset of action, which would be especially helpful for patients experiencing treatment resistant depression, and agitation. We further explore the mechanistic and clinical implications of considering DEX as a putative antidepressant agent, and the next steps to explore the efficacy of low dose DEX infusion among patients with treatment resistant depression.
- Published
- 2020
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50. Trait Emotional Intelligence and Its Correlates in Oman Medical Specialty Board Residents.
- Author
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Al Huseini S, Al Alawi M, Al Sinawi H, Al-Balushi N, Jose S, and Al-Adawi S
- Subjects
- Cross-Sectional Studies, Education, Medical, Graduate, Female, Humans, Male, Oman, Reproducibility of Results, Socioeconomic Factors, Surveys and Questionnaires, Emotional Intelligence, Internship and Residency, Specialty Boards
- Abstract
Background: As part of the globalization of medical education, residency programs in Oman have adopted competency-based standards by the Accreditation Council for Graduate Medical Education International (ACGME-I). Correctly perceiving the emotions of others and managing one's own emotions are essential to high-quality patient care., Objective: We tested the reliability and construct validity of the Trait Emotional Intelligence Questionnaire-Short Form (TEIQue-SF), and assessed trait Emotional Intelligence (EI) in Oman Medical Specialty Board (OMSB) residents in multiple specialties. We explored for correlations with trainees' sociodemographic background data., Methods: We conducted a cross-sectional, observational study between February and August 2017. Participants were OMSB residents. We administered the TEIQue-SF and collected sociodemographic data from participants. Multiple linear regression analysis was conducted to identify independent predictors of trait EI., Results: The present cohort scored high in the trait EI subscale of Well-being, followed by Sociability, Self-control, and Emotionality. Among sociodemographic factors, female gender and high income were significant predictors of TEIQue-SF's Well-being subscale and high income and living in a rented home were significant predictors of the Sociability subscale., Conclusions: This is the first study conducted among medical residents in Oman regarding trait EI and its correlates. Our findings of overall high EI and several socioeconomic predictors echo the literature on the assessment of EI in trainees. The findings add to the evidence of cross-cultural applicability of instruments to measure trait EI, and use assessments of EI in resident selection and education., Competing Interests: Conflict of interest: The authors declare they have no competing interests.
- Published
- 2019
- Full Text
- View/download PDF
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