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Your search keyword '"Akwiwu, Eddymurphy U."' showing total 25 results
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1. A Bayesian accelerated failure time model for interval censored three-state screening outcomes

Author

Klausch, Thomas, Akwiwu, Eddymurphy U., van de Wiel, Mark A., Coupe, Veerle M. H., and Berkhof, Johannes

Subjects
Statistics - Methodology, 62N02
Abstract

Women infected by the Human papilloma virus are at an increased risk to develop cervical intraepithalial neoplasia lesions (CIN). CIN are classified into three grades of increasing severity (CIN-1, CIN-2, and CIN-3) and can eventually develop into cervical cancer. The main purpose of screening is detecting CIN-2 and CIN-3 cases which are usually surgically removed. Screening data from the POBASCAM trial involving 1,454 HPV-positive women is analyzed with two objectives: estimate (a) the transition time from HPV diagnosis to CIN-3; and (b) the transition time from CIN-2 to CIN-3. The screening data have two key characteristics. First, the CIN state is monitored in an interval-censored sequence of screening times. Second, a woman's progression to CIN-3 is only observed, if the woman progresses to, both, CIN-2 and from CIN-2 to CIN-3 in the same screening interval. We propose a Bayesian accelerated failure time model for the two transition times in this three-state model. To deal with the unusual censoring structure of the screening data, we develop a Metropolis-within-Gibbs algorithm with data augmentation from the truncated transition time distributions., Comment: 22 pages (Manuscript), 34 pages (Supplemental Material)

Published
2021

5. TABLE 3 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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6. TABLE 4 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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7. FIGURE 1 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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8. Supplementary Figure 1 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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9. TABLE 7 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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10. Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., additional, Lemmens, Margriet, additional, Delis-van Diemen, Pien M., additional, Klotz, Dagmar, additional, Leon, Leticia G., additional, Lakbir, Soufyan, additional, de Wit, Meike, additional, Fijneman, Remond J.A., additional, van Leerdam, Monique E., additional, Dekker, Evelien, additional, Spaander, Manon C.W., additional, Meijer, Gerrit A., additional, Løberg, Magnus, additional, Coupé, Veerle M.H., additional, Kalager, Mette, additional, and Carvalho, Beatriz, additional

Published
2023
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11. TABLE 5 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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12. Supplementary Figure 2 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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13. TABLE 6 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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14. Data from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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15. FIGURE 2 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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16. TABLE 2 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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17. TABLE 1 from Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case–Control Study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., primary, Lemmens, Margriet, primary, Delis-van Diemen, Pien M., primary, Klotz, Dagmar, primary, Leon, Leticia G., primary, Lakbir, Soufyan, primary, de Wit, Meike, primary, Fijneman, Remond J.A., primary, van Leerdam, Monique E., primary, Dekker, Evelien, primary, Spaander, Manon C.W., primary, Meijer, Gerrit A., primary, Løberg, Magnus, primary, Coupé, Veerle M.H., primary, Kalager, Mette, primary, and Carvalho, Beatriz, primary

Published
2023
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20. Abstract A004: Molecular adenoma features to predict metachronous colorectal cancer risk: A nested-case control study

Author

Jodal, Henriette C., primary, Akwiwu, Eddymurphy U., additional, Leon, Leticia G., additional, Lemmens, Margriet, additional, Delis-van Diemen, Pien, additional, Klotz, Dagmar, additional, de Wit, Meike, additional, Fijneman, Remond, additional, van Leerdam, Monique, additional, Dekker, Evelien, additional, Spaander, Manon C. W., additional, Meijer, Gerrit A., additional, Bretthauer, Michael, additional, Løberg, Magnus, additional, Coupé, Veerle M. H., additional, Kalager, Mette, additional, and Carvalho, Beatriz, additional

Published
2022
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23. Selection for health professions education leads to increased inequality of opportunity and decreased student diversity in The Netherlands, but lottery is no solution: A retrospective multi-cohort study

Author

Mulder, Lianne, primary, Wouters, Anouk, additional, Twisk, Jos W. R., additional, Koster, Andries S., additional, Akwiwu, Eddymurphy U., additional, Ravesloot, Jan H., additional, Croiset, Gerda, additional, and Kusurkar, Rashmi A., additional

Published
2022
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24. Fitting a progressive three-state colorectal cancer model to interval-censored surveillance data under outcome-dependent sampling using a weighted likelihood approach.

Author

Akwiwu EU, Klausch T, Jodal HC, Carvalho B, Løberg M, Kalager M, Berkhof J, and Coupé VMH

Abstract

To optimize colorectal cancer (CRC) surveillance, accurate information on the risk of developing CRC from premalignant lesions is essential. However, directly observing this risk is challenging since precursor lesions, i.e., advanced adenomas (AAs), are removed upon detection. Statistical methods for multistate models can estimate risks, but estimation is challenging due to low CRC incidence. We propose an outcome-dependent sampling (ODS) design for this problem in which we oversample CRCs. More specifically, we propose a three-state model for jointly estimating the time distributions from baseline colonoscopy to AA and from AA onset to CRC accounting for the ODS design using a weighted likelihood approach. We applied the methodology to a sample from a Norwegian adenoma cohort (1993-2007), comprising 1, 495 individuals (median follow-up 6.8 years [IQR: 1.1 - 12.8 years]) of whom 648 did and 847 did not develop CRC. We observed a 5-year AA risk of 13% and 34% for individuals having non-advanced adenoma (NAA) and AA removed at baseline colonoscopy, respectively. Upon AA development, the subsequent risk to develop CRC in 5 years was 17% and age-dependent. These estimates provide a basis for optimizing surveillance intensity and determining the optimal trade-off between CRC prevention, costs, and use of colonoscopy resources., (© The Author(s) 2024. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)

Published
2024
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