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2. Evaluation of 601 children with multisystem inflammatory syndrome (Turk MISC study)

Author

Yilmaz, Dilek, Ekemen Keles, Yildiz, Emiroglu, Melike, Duramaz, Burcu Bursal, Ugur, Cuneyt, Aldemir Kocabas, Bilge, Celik, Talyan, Ozdemir, Halil, Bayturan, Semra, Turel, Ozden, Erdeniz, Emine Hafize, Cakici, Ozlem, Cakmak Taskin, Esra, Erbas, İrem Ceren, Genceli, Mustafa, Sari, Emine Ergul, Caymaz, Canan, Kizil, Mahmut Can, Sutcu, Murat, Demirbuga, Asuman, Alkan, Gulsum, Bagcı, Zafer, Timurtas Dayar, Gulperi, Ozkan, Esra Akyuz, Tekin Yilmaz, Ayse, Akca, Mehtap, Yesil, Edanur, Kara, Soner Sertan, Akturk, Hacer, Yasar, Belma, Umit, Zuhal, Uygun, Hatice, Erdem, Nurettin, Buyukcam, Ayse, Karadag Oncel, Eda, Tuter Oz, Sadiye Kubra, Cetin, Hafize Selma, Anil, Ayse Berna, Yilmaz, Resul, Zengin, Neslihan, Uzuner, Selcuk, Albayrak, Hatice, Borakay, Ozgur, Topal, Sevgi, Arslan, Gazi, Yazar, Abdullah, Ozer, Arife, Kendirli, Tanil, Kara, Emine Manolya, Demirkol, Demet, Battal, Fatih, Kosker, Muhammet, Metin Akcan, Ozge, Kihtir, Hasan Serdar, Gul, Doruk, Zararci, Kazim, Alakaya, Mehmet, Kula, Nilgun, Celik, Elif, Petmezci, Ercument, Evren, Gultac, Kara Aksay, Ahu, Konca, Capan, Sert, Ahmet, Arslan, Derya, Bornaun, Helen, Tekeli, Onur, Bal, Alkan, Sahin, Irfan Oguz, Demir, Selcan, Sap, Fatih, Akyol, Mehmet Bedir, Tanidir, Ibrahim Cansaran, Donmez, Yasemin Nuran, Ucar, Tayfun, Coban, Senay, Arga, Gul, Hancerli Torun, Selda, Karpuz, Derya, Celik, Serkan Fazli, Varan, Celal, Elmali, Ferhan, Oncel, Selim, Belet, Nursen, Hatipoglu, Nevin, Dalgic Karabulut, Nazan, Turgut, Mehmet, Somer, Ayper, Kuyucu, Necdet, Dinleyici, Ener Cagri, Ciftci, Ergin, and Kara, Ates

Published
2023
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6. Diphtheria and Hearing Loss

Author

Kara Aksay, Ahu, Yılmaz Çiftdoğan, Dilek, Tenenbaum, Tobias, Cingi, Cemal, Series Editor, Arısoy, Ayşe Engin, editor, Arısoy, Emin Sami, editor, Bayar Muluk, Nuray, editor, and Correa, Armando G., editor

Published
2023
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11. COVID-19 associated multisystemic inflammatory syndrome in 614 children with and without overlap with Kawasaki disease-Turk MIS-C study group

Author

Yilmaz Ciftdogan, Dilek, Ekemen Keles, Yildiz, Cetin, Benhur Sirvan, Dalgic Karabulut, Nazan, Emiroglu, Melike, Bagci, Zafer, Buyukcam, Ayse, Erdeniz, Emine Hafize, Arga, Gul, Yesil, Edanur, Cakici, Ozlem, Karbuz, Adem, Sahbudak Bal, Zumrut, Kara, Soner Sertan, Ozer, Arife, Metin Akcan, Ozge, Elmas Bozdemir, Sefika, Anil, Ayse Berna, Uygun, Hatice, Kilic, Omer, Hancerli Torun, Selda, Umit, Zuhal, Sutcu, Murat, Ozgokce Ozmen, Berfin, Karaoglu Asrak, Hatice, Alkan, Gulsum, Kara Aksay, Ahu, Ugur, Cuneyt, Birbilen, Ahmet Ziya, Bursal Duramaz, Burcu, Akyuz Ozkan, Esra, Burakay, Ozgur, Yildirim Arslan, Sema, Karadag Oncel, Eda, Celik, Serkan Fazli, Kilic, Ahmet Osman, Ozen, Seval, Sarikaya, Remzi, Demirkol, Demet, Arslan, Gazi, Turel, Ozden, Sert, Ahmet, Sari, Ergul, Orbak, Zerrin, Sahin, Irfan Oguz, Varan, Celal, Akturk, Hacer, Tuter Oz, Sadiye Kubra, Durak, Fatih, Oflaz, Mehmet Burhan, Kara, Manolya, Karpuz, Derya, Talip Petmezci, Mey, Hatipoglu, Nevin, Oncel, Selim, Turgut, Mehmet, Elmali, Ferhan, Somer, Ayper, Kuyucu, Necdet, Dinleyici, Ener Cagri, Kurugöl, Zafer, Ciftci, Ergin, and Kara, Ates

Published
2022
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14. Response to `attitudes of parents with children aged 12-18 to covid-19 vaccines for themselves and their children: vaccine hesitancy in türkiye`

Author

Şahin, Aslıhan, primary, Kara-Aksay, Ahu, additional, Aşcı, Bahri, additional, Ekemen-Keleş, Yıldız, additional, Üstundağ, Gülnihan, additional, Elvan-Tüz, Ayşegül, additional, Taşar, Selin, additional, Arslan-Maden, Aslıhan, additional, İnce, Gülberat, additional, Kanık, Ali, additional, Karadağ-Öncel, Eda, additional, Elmalı, Ferhan, additional, and Yılmaz, Dilek, additional

Published
2024
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15. Rare Presentation of Anthrax: Preseptal Cellulitis.

Author

Tan, Ayça Kömürlüoğlu, Aksay, Ahu Kara, and Özeç, Ayşe Vural

Subjects
ANTHRAX, ZOONOSES, BACILLUS anthracis, COMMUNICABLE diseases, CELLULITIS, PHYSICIANS
Abstract

Copyright of Anatolian Journal of General Medical Research is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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17. Evaluation of ischemia-modified albumin in the diagnosis and the clinical severity of COVID-19 in children

Author

Öncel, Eda Karadağ, primary, Yılmaz, Dilek, additional, Kara Aksay, Ahu, additional, Neşelioğlu, Salim, additional, İşbilen Başok, Banu, additional, Karakoyun, İnanç, additional, Altan, Tuba Kansu, additional, Taşar, Selin, additional, Üstündağ, Gülnihan, additional, Şahin, Aslıhan, additional, Keleş, Yıldız Ekemen, additional, Tüz, Ayşegül Elvan, additional, and Erel, Özcan, additional

Published
2023
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18. Clinical Reflections of Acinetobacter Infections in Children in a Quaternary-Care Hospital: A Five-Year Single-Center Experience.

Author

Elvan-Tüz, Ayşegül, Tekin, Duygu, Ekemen-Keleş, Yıldız, Şahin, Aslıhan, Üstündağ, Gülnihan, Taşar, Selin, Kara-Aksay, Ahu, Karadağ-Öncel, Eda, and Yılmaz, Dilek

Subjects
INTENSIVE care units, ACINETOBACTER infections, URINARY tract infections, RETROSPECTIVE studies, ACQUISITION of data, RISK assessment, INFECTION, MEDICAL records, DESCRIPTIVE statistics, LONGITUDINAL method, DISEASE risk factors, CHILDREN
Abstract

Objective: This study aimed to determine the epidemiology of Acinetobacter species in the last 5 years, the clinical diseases caused by the pathogen, the possible risk factors for infection, and the resistance pattern of the microorganism in our quaternary-care hospital. Materials and Methods: In this retrospective cohort study, 67 pediatric cases infected with Acinetobacter species in our hospital between January 2017 and December 2021 were analyzed. Demographic characteristics and clinical and laboratory findings were analyzed. Results: In pediatric patients infected with Acinetobacter spp., the median age was 36 (7-114) months, and 64.2% (n = 43) were female. Acinetobacter baumannii was grown in the cultures of 31 (46.3%) cases. When the type of infection was examined, 31 (46.3%) cases were urinary tract infections, and 29 (43.3%) cases were bloodstream infections. Extensively drug-resistant, pandrug-resistant, and multidrug-resistant A. baumannii were found in 10 (14.9%), 3 (4.5%), and 2 (3%) cases, respectively. Health-care-associated infections were found to have a significant rate of Acinetobacter resistance (P = .002). Significant antimicrobial resistance was detected in Acinetobacter-infected cases with intensive care hospitalization within the last month and carbapenem use in the previous 3 months (P < .001, both). Conclusion: It is necessary to act in accordance with the infection prevention and control program to reduce the incidence of health-care-associated infections with Acinetobacter species and to prevent infection with highly resistant strains. Due to health-care-associated infections and factors contributing to the increase in Acinetobacter resistance, we believe this study will help clinicians to be more cautious in the use of carbapenems. [ABSTRACT FROM AUTHOR]

Published
2024
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20. The diversity in the clinical features of children hospitalized with COVID‐19 during the nonvariant, Alpha (B.1.1.7), Delta (B.1.617.2), and Omicron (B.1.1.529) variant periods of SARS CoV‐2: Caution for neurological symptoms in Omicron variant

Author

Sahin, Aslıhan, primary, Karadag‐Oncel, Eda, additional, Buyuksen, Osman, additional, Ekemen‐Keles, Yildiz, additional, Ustundag, Gulnihan, additional, Elvan‐Tuz, Aysegul, additional, Tasar, Selin, additional, Didinmez‐Taskirdi, Elif, additional, Baykan, Muge, additional, Kara‐Aksay, Ahu, additional, Yilmaz, Nisel, additional, Olgac‐Dundar, Nihal, additional, and Yilmaz, Dilek, additional

Published
2023
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23. COVID-19 Obez Çocuklarda Daha Ağır mı Seyrediyor?

Author

ARSLAN MADEN, Aslıhan, primary, EKEMEN KELEŞ, Yıldız, additional, KARADAG-ONCEL, Eda, additional, ÜSTÜNDAĞ, Gülnihan, additional, ŞAHİN, Aslıhan, additional, ELVAN TÜZ, Ayşegül, additional, TAŞAR, Selin, additional, MANYAS, Hayrullah, additional, KARA AKSAY, Ahu, additional, YILMAZ ÇİFTDOĞAN, Dilek, additional, and DÜNDAR, Bumin, additional

Published
2022
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26. Hydatid Disease in Children from Diagnosis to Treatment: A 10-year Single Center Experience

Author

Tüz, Ayşegül Elvan, primary, Ekemen Keleş, Yıldız, additional, Şahin, Aslıhan, additional, Üstündağ, Gülnihan, additional, Taşar, Selin, additional, Karadağ Öncel, Eda, additional, Kara Aksay, Ahu, additional, Öztan, Mustafa Onur, additional, Köylüoğlu, Gökhan, additional, Çapar, Ahmet Ergin, additional, and Yılmaz Çiftdoğan, Dilek, additional

Published
2022
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27. Prevalence of Anosmia in 10.157 Pediatric COVID-19 Cases: Multicenter Study from Turkey

Author

Ciftdogan, Dilek Yilmaz, Demirbuga, Asuman, Gungor, Emre, Aygun, Fatma Deniz, Sahinkaya, Sahika, Bulbul, Lida, Uysalol, Metin, Cura Yayla, Burcu Ceylan, Aykac, Kubra, Tekin, Ayse, Caglar, Ilknur, Ozdem, Suna, Ozcan, Nur, Bilen, Nimet Melis, Buyukcam, Ayse, Kara, Ates, Turgut, Mehmet, Kurugol, Zafer, Cokugras, Haluk Cezmi, Devrim, Ilker, Belet, Nursen, Ciftci, Ergin, Alabaz, Derya, Kilic, Omer, Oncel, Selim, Aksay, Ahu Kara, Torun, Selda Hancerli, Ozsurekci, Yasemin, Bal, Zumrut Sahbudak, Tekin, Deniz, Kocabas, Bilge Aldemir, Turel, Ozden, Ozer, Arife, Uygun, Hatice Uyanik, Umit, Zuhal, Bolat, Ahmet, Kara, Manolya, Sutcu, Murat, Yesil, Edanur, Arikan, Kamile, Genceli, Mustafa, Vatansever, Goksel, Akca, Mehtap, Ozmen, Berfin Ozgokce, Sahin, Emre, Dogan, Yunus Emre, Guney, Ahmet Yasin, Mustafaoglu, Ozlem, Kara, Soner Sertan, Cukurova, Ibrahim, Teksam, Ozlem, Apaydin, Gozde, Cem, Ela, Demir, Tugba, Sen, Semra Bayturan, Bal, Alkan, Bursal-Duramaz, Burcu, Polat, MELTEM, Akcan, Ozge Metin, Elmas-Bozdemir, Sefika, Egil, Oguz, Ozdemir, Halil, Kuyucu, Necdet, Ozdem-Alatas, Silem, Hacimustafaoglu, Mustafa, Gulhan, Belgin, Kanik-Yuksek, Saliha, Kiran, Sibel, Karadag-Oncel, Eda, Elvan-Tuz, Aysegul, Cakici, Ozlem, Erdeniz, Emine Hafize, Ozkan, Esra Akyuz, Basaranoglu, Sevgen Tanir, Dayar, Gulperi Timurtas, Kosker, Muhammet, Kara, Yalcin, Kizil, Mahmut Can, Celik, Taylan, Cay, Ummuhan, Cetin, Ceren, Karaaslan, Ayse, and Cetin, Benhur Sirvan

Subjects
Microbiology (medical), Adult, Adolescent, Turkey, SARS-CoV-2, Anosmia, COVID-19, Cohort Studies, Infectious Diseases, Pediatrics, Perinatology and Child Health, Prevalence, Humans, Prospective Studies, Ageusia, Child
Abstract

Introduction: COVID-19-related anosmia is a remarkable and disease-specific finding. With this multicenter cohort study, we aimed to determine the prevalence of anosmia in pediatric cases with COVID-19 from Turkey and make an objective assessment with a smell awareness questionnaire. Material and Methods: This multicenter prospective cohort study was conducted with pediatric infection clinics in 37 centers in 19 different cities of Turkey between October 2020 and March 2021. The symptoms of 10.157 COVID-19 cases 10-18 years old were examined. Age, gender, other accompanying symptoms, and clinical severity of the disease of cases with anosmia and ageusia included in the study were recorded. The cases were interviewed for the smell awareness questionnaire at admission and one month after the illness. Results: Anosmia was present in 12.5% (1.266/10.157) of COVID-19 cases 10-18 years of age. The complete records of 1053 patients followed during the study period were analyzed. The most common symptoms accompanying symptoms with anosmia were ageusia in 885 (84%) cases, fatigue in 534 cases (50.7%), and cough in 466 cases (44.3%). Anosmia was recorded as the only symptom in 84 (8%) of the cases. One month later, it was determined that anosmia persisted in 88 (8.4%) cases. In the smell awareness questionnaire, the score at admission was higher than the score one month later (P < 0.001). Discussion: With this study, we have provided the examination of a large case series across Turkey. Anosmia and ageusia are specific symptoms seen in cases of COVID-19. With the detection of these symptoms, it should be aimed to isolate COVID-19 cases in the early period and reduce the spread of the infection. Such studies are important because the course of COVID-19 in children differs from adults and there is limited data on the prevalence of anosmia.

Published
2022

29. Can Serum 25-Hydroxy Vitamin D Levels Predict the Severity of Multisystem Inflammatory Syndrome in Children and COVID-19?

Author

Keleş, Yıldız Ekemen, Yılmaz, Dilek, Taşar, Selin, Üstündağ, Gülnihan, Şahin, Aslıhan, Tuz, Ayşegül Elvan, Maden, Aslıhan Arslan, Aksay, Ahu Kara, Çolak, Ayfer, and Öncel, Eda Karadağ

Subjects
COVID-19, MULTISYSTEM inflammatory syndrome, VITAMIN D, SEVERITY of illness index, GLASGOW Coma Scale, DESCRIPTIVE statistics, CHILDREN
Abstract

Objective: To determine the clinical significance of serum 25-hydroxy (OH) vitamin D levels in pediatric patients with multisystem inflammatory syndrome in children (MIS-C) and compare the vitamin D levels of these patients with those patients with Coronavirus disease-2019 (COVID-19) and healthy controls. Methods: This study was designed for pediatric patients aged 1 month to 18 years and conducted between July 14 and December 25, 2021. Fifty-one patients with MIS-C, 57 who were hospitalized with COVID-19, and 60 controls were enrolled in the study. Vitamin D insufficiency was defined as a serum 25 (OH) vitamin D level of less than 20 ng/mL. Severe MIS-C was classified as necessitating intensive care due to cardiovascular instability, the necessity for non-invasive or invasive mechanical ventilation, and/or a diminishing Glasgow coma scale. World Health Organization definition criteria were used to describe the clinical stages of COVID-19 in children and patients were divided into four groups according to the clinical severity of COVID-19: asymptomatic, mild, moderate, and severe/critical. Results: The median serum 25 (OH) vitamin D was 14.6 ng/mL in patients with MIS-C, 16 ng/mL in patients with COVID-19, and 21.1 ng/mL in the control group (p<0.001). Vitamin D insufficiency was present in 74.5% (n=38) of patients with MIS-C, 66.7% (n=38) of patients with COVID-19, and 41.7% (n=25) of the controls (p=0.001). The percentage of four or more affected organ systems was 39.2% in patients with MIS-C. The correlation between the number of affected organ systems and serum 25 (OH) vitamin D levels was evaluated in patients with MIS-C and there was a moderate negative correlation (r=-0.310; p=0.027). A weak negative correlation was found between the severity of COVID-19 and serum 25 (OH) vitamin D (r=-0.320, p=0.015). Conclusion: Vitamin D levels were insufficient in both the MIS-C and COVID groups. Furthermore, vitamin D levels correlated with the number of affected organ systems in MIS-C and the severity of COVID-19. [ABSTRACT FROM AUTHOR]

Published
2023
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30. Thorax Computed Tomography Imaging and Chest X-Rays Results in Children with Different Clinical-Stages of COVID-19.

Author

Keleş, Yıldız Ekemen, Pekçevik, Yeliz, Yılmaz, Dilek, Sarıoğlu, Fatma Ceren, Demirçelik, Yavuz, Aksay, Ahu Kara, Üstündağ, Gülnihan, Şahin, Aslıhan, Taş, Sebahat, Kanık, Ali, and Belet, Ümit

Abstract

Copyright of Journal of Pediatric Infection / Çocuk Enfeksiyon Dergisi is the property of Journal of Pediatric Infection / Cocuk Enfeksiyon Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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31. COVID-19 associated multisystemic inflammatory syndrome in 614 children with and without overlap with Kawasaki disease-Turk MIS-C study group

Author

Aktürk, Hacer, Çiftdoğan, Dilek Yılmaz; Keleş, Yıldız Ekemen; Çetin, Benhur Şirvan; Karabulut, Nazan Dalgıç; Emiroğlu, Melike; Bağcı, Zafer; Büyükçam, Ayşe; Erdeniz, Emine Hafize; Arga, Gül; Yeşil, Edanur; Çakıcı, Özlem; Karbuz, Adem; Bal, Zümrüt Şahbudak; Kara, Soner Sertan; Özer, Arife; Akcan, Özge Metin; Bozdemir, Şefika Elmas; Anıl, Ayşe Berna; Uygun, Hatice; Kılıç, Ömer; Torun, Selda Hancerli; Ümit, Zuhal; Sütcü, Murat; Özmen, Berfin ÖzgÖkce; Asrak, Hatice Karaoğlu; Alkan, Gülsüm; Aksay, Ahu Kara; Uğur, Cüneyt; Birbilen, Ahmet Ziya; Duramaz, Burcu Bursal; Özkan, Esra Akyüz; Burakay, Özgür; Arslan, Sema Yıldırım; Öncel, Eda Karadağ; Celik, Serkan Fazlı; Kılıç, Ahmet Osman; Özen, Seval; Sarıkaya, Remzi; Demirkol, Demet; Arslan, Gazi; Türel, Özden; Sert, Ahmet; Sarı, Ergül; Orbak, Zerrin; Şahin, İrfan Oğuz; Varan, Celal; Öz, Sadiye Kübra Tuter; Durak, Fatih; Oflaz, Mehmet Burhan; Kara, Manolya; Karpuz, Derya; Petmezci, Mey Talip; Hatipoğlu, Nevin; Öncel, Selim; Turgut, Mehmet; Elmalı, Ferhan; Somer, Ayper; Kuyucu, Necdet; Dinleyici, Ener Cağrı; Kurugöl, Zafer; Çiftci, Ergin; Kara, Ateş, Koç University Hospital, Aktürk, Hacer, Çiftdoğan, Dilek Yılmaz; Keleş, Yıldız Ekemen; Çetin, Benhur Şirvan; Karabulut, Nazan Dalgıç; Emiroğlu, Melike; Bağcı, Zafer; Büyükçam, Ayşe; Erdeniz, Emine Hafize; Arga, Gül; Yeşil, Edanur; Çakıcı, Özlem; Karbuz, Adem; Bal, Zümrüt Şahbudak; Kara, Soner Sertan; Özer, Arife; Akcan, Özge Metin; Bozdemir, Şefika Elmas; Anıl, Ayşe Berna; Uygun, Hatice; Kılıç, Ömer; Torun, Selda Hancerli; Ümit, Zuhal; Sütcü, Murat; Özmen, Berfin ÖzgÖkce; Asrak, Hatice Karaoğlu; Alkan, Gülsüm; Aksay, Ahu Kara; Uğur, Cüneyt; Birbilen, Ahmet Ziya; Duramaz, Burcu Bursal; Özkan, Esra Akyüz; Burakay, Özgür; Arslan, Sema Yıldırım; Öncel, Eda Karadağ; Celik, Serkan Fazlı; Kılıç, Ahmet Osman; Özen, Seval; Sarıkaya, Remzi; Demirkol, Demet; Arslan, Gazi; Türel, Özden; Sert, Ahmet; Sarı, Ergül; Orbak, Zerrin; Şahin, İrfan Oğuz; Varan, Celal; Öz, Sadiye Kübra Tuter; Durak, Fatih; Oflaz, Mehmet Burhan; Kara, Manolya; Karpuz, Derya; Petmezci, Mey Talip; Hatipoğlu, Nevin; Öncel, Selim; Turgut, Mehmet; Elmalı, Ferhan; Somer, Ayper; Kuyucu, Necdet; Dinleyici, Ener Cağrı; Kurugöl, Zafer; Çiftci, Ergin; Kara, Ateş, and Koç University Hospital

Abstract

Multisystemic inflammatory syndrome (MIS-C) diagnosis remains difficult because the clinical features overlap with Kawasaki disease (KD). The study aims to highlight the clinical and laboratory features and outcomes of patients with MISC whose clinical manifestations overlap with or without KD. This study is a retrospective analysis of a case series designed for patients aged 1 month to 18 years in 28 hospitals between November 1, 2020, and June 9, 2021. Patient demographics, complaints, laboratory results, echocardiographic results, system involvement, and outcomes were recorded. A total of 614 patients were enrolled; the median age was 7.4 years (interquartile range (IQR) 3.9-12 years). A total of 277 (45.1%) patients with MIS-C had manifestations that overlapped with KD, including 92 (33.3%) patients with complete KD and 185 (66.7%) with incomplete KD. Lymphocyte and platelet counts were significantly lower in patients with MISC, overlapped with KD (lymphocyte count 1080 vs. 1280 cells x mu L, p = 0.028; platelet count 166 vs. 216 cells x 10(3)/mu L, p < 0.001). The median serum procalcitonin levels were statistically higher in patients overlapped with KD (3.18 vs. 1.68 mu g/L, p = 0.001). Coronary artery dilatation was statistically significant in patients with overlap with KD (13.4% vs. 6.8%, p = 0.007), while myocarditis was significantly more common in patients without overlap with KD features (2.6% vs 7.4%, p = 0.009). The association between clinical and laboratory findings and overlap with KD was investigated. Age > 12 years reduced the risk of overlap with KD by 66% (p < 0.001, 95% CI 0.217-0.550), lethargy increased the risk of overlap with KD by 2.6-fold (p = 0.011, 95% CI 1.244-5.439), and each unit more albumin (g/dl) reduced the risk of overlap with KD by 60% (p < 0.001, 95% CI 0.298-0.559). Conclusion: Almost half of the patients with MISC had clinical features that overlapped with KD; in particular, incomplete KD was present. The median age was low, NA

Published
2022

34. Attitudes of parents with children aged 12-18 to COVID-19 vaccines for themselves and their children.

Author

Şahin, Aslıhan, Aksay, Ahu Kara, Aşcı, Bahri, Keleş, Yıldız Ekemen, Üstündağ, Gülnihan, Tüz, Ayşegül Elvan, Taşar, Selin, Maden, Aslıhan Arslan, İnce, Gülberat, Kanık, Ali, Öncel, Eda Karadağ, Elmalı, Ferhan, and Yılmaz, Dilek

Abstract

Background. The incidence of vaccine hesitancy is increasing in many countries. This study aims to determine parents’ attitudes and related factors regarding COVID-19 vaccine acceptance for themselves and their children aged 12-18. Methods. A cross-sectional survey was conducted on parents between 16th November and 31st December 2021, after COVID-19 vaccines were initiated for children in Türkiye. In the survey, the sociodemographic characteristics of the parents, whether they and their children were vaccinated against COVID-19, and if not, the reasons for this were asked. Multivariate binary logistic regression analysis was used to evaluate the factors affecting parents’ refusal to vaccinate their children for COVID-19. Results. Three hundred and ninety-six mothers and fathers were included in the final analysis. Overall, 41.7% of parents reported vaccine refusal for their children. COVID-19 vaccine refusal was higher in mothers younger than 35 (β = 6.5, p = 0.002, 95% CI: 2.0-23.1), children aged 15 and younger (β = 2.3, p = 0.001, 95% CI: 1.4-3.7). Concerns about the side effects of the COVID-19 vaccine (29.7%) and their children not wanting to be vaccinated (29.0%) were the most common causes of COVID-19 vaccine refusal. Conclusions. In the present study, the rate of children not vaccinated due to COVID-19 vaccine refusal was relatively high. Parents’ concerns about vaccine side effects, as well as their children’s unwillingness to be vaccinated, suggest that both parents and adolescents should be informed about the importance of COVID-19 vaccines. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Multisystem inflammatory syndrome in children associated with COVID ‐19 in 101 cases from Turkey ( Turk‐MISC study)

Author

Yilmaz Ciftdogan, Dilek, primary, Ekemen Keles, Yildiz, additional, Karbuz, Adem, additional, Cetin, Benhur Sirvan, additional, Elmas Bozdemir, Sefika, additional, Kepenekli Kadayifci, Eda, additional, Metin Akcan, Ozge, additional, Ozer, Arife, additional, Erat, Tugba, additional, Sutcu, Murat, additional, Buyukcam, Ayse, additional, Belet, Nursen, additional, Erdeniz, Emine Hafize, additional, Dalgic Karabulut, Nazan, additional, Hancerli Torun, Selda, additional, Oncel, Selim, additional, Orbak, Zerrin, additional, Turel, Ozden, additional, Gayretli Aydin, Zeynep Gokce, additional, Kilic, Omer, additional, Yahsi, Aysun, additional, Kara Aksay, Ahu, additional, Ergenc, Zeynep, additional, Petmezci, Mey Talip, additional, Oflaz, Mehmet Burhan, additional, Sarikaya, Remzi, additional, Otar Yener, Gülcin, additional, Ozen, Seval, additional, Gul, Doruk, additional, Arslan, Gazi, additional, Kara, Soner Sertan, additional, Demirkol, Demet, additional, Yazici Ozkaya, Pinar, additional, Yozgat, Yilmaz, additional, Varan, Celal, additional, Kara, Manolya, additional, Arga, Gul, additional, Yakut, Nurhayat, additional, Kilic, Ahmet Osman, additional, Cakici, Ozlem, additional, Kucuk, Mehmet, additional, Kaba, Ozge, additional, Karaoglu Asrak, Hatice, additional, Bursal Duramaz, Burcu, additional, Dalkiran, Tahir, additional, Berna Anil, Ayse, additional, Turgut, Mehmet, additional, Karapinar, Bulent, additional, Somer, Ayper, additional, Elmali, Ferhan, additional, Dinleyici, Ener Cagri, additional, Ciftci, Ergin, additional, and Kara, Ates, additional

Published
2022
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39. COVID‐19 in healthy children: What is the effect of household contact?

Author

Ustundag, Gulnihan, Yilmaz‐Ciftdogan, Dilek, Kara‐Aksay, Ahu, Sahin, Aslihan, Ekemen‐Keles, Yildiz, Orsdemir‐Hortu, Hacer, Kanik, Muhammet Ali, Yuksel, Necmi Can, Aslan, Fatma Demet, and Ozkalay‐Yilmaz, Nisel

Subjects
Adult, Family Characteristics, SARS-CoV-2, transmission, COVID-19, Original Articles, SARS‐CoV‐2, household, children, COVID‐19, Humans, Original Article, Female, Child
Abstract

Background Coronavirus disease 2019 (COVID‐19) in children is milder compared with adults. It is considered that household virus exposure may affect clinical severity. We aimed to determine the household contact history of patients and its influence on the clinical stage. Methods One hundred seventy‐three pediatric patients with COVID‐19 as diagnosed with positive real‐time polymerase chain reaction for severe acute respiratory syndrome coronavirus‐2 aged one month to 18 years were included. Demographic data, laboratory and clinical findings, and the history of household contact (with or without) of the patients were obtained. They were classified according to their clinical stage as mild or moderate‐severe. Results Sixty patients (34.7%) were asymptomatic, and 113 were symptomatic (65.3%). Of the 173 patients, 138 (79.8%) had at least one family member in the household who was diagnosed as having COVID‐19. Hemoglobin, absolute neutrophil count (ANC), and ANC/absolute lymphocyte count ratio decreased significantly in patients with household contact. The presence of a household contact had not significant effect on the presence of symptoms, clinical course, age, and the sex of the patients. The need for hospitalization was less in the group that had household contact. Being 0‐12 months and female sex, and the patients without household contact were independent factors associated with higher hospitalization ratios in logistic regression analysis. Conclusions In this study, we found that household contact history did not significantly affect presenting symptoms and clinical course. We detected the rate of hospitalization to be less in the group with only household contact.

Published
2021

41. Evaluation of Attitudes and Knowledge of Influenza Diagnosis, Treatment and Vaccination Among Pediatric Residents

Author

Garipçin, Pınar, primary, Ekemen Keleş, Yıldız, additional, Karadağ Öncel, Eda, additional, Kıymet, Elif, additional, Böncüoğlu, Elif, additional, Okumuş Özlü, Canan, additional, Karaoğlu Asrak, Hatice, additional, Güner Özenen, Gizem, additional, Ümit, Zuhal, additional, Kara, Soner Sertan, additional, Şen, Semra, additional, Kara Aksay, Ahu, additional, Şahbudak Bal, Zümrüt, additional, Devrim, İlker, additional, Belet, Nurşen, additional, and Yılmaz Çiftdoğan, Dilek, additional

Published
2021
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45. COVID-19 hastalığı ile ilişkili çoklu Sistemik inflamatuvar sendrom tanılı çocuk olguların değerlendirilmesi

Author

GÜL, DORUK, ÇETİN, BENHUR ŞİRVAN, Petmezci, Mey Talip, KARA, ATEŞ, Aksay, Ahu Kara, KARA, EMİNE MANOLYA, DEMİRKOL, DEMET, SÜTÇÜ, MURAT, Dalgıç Karabulut, Nazan, BÜYÜKCAM, AYŞE, YAKUT, NURHAYAT, Erdeniz, Emine, KABA, ÖZGE, KEPENEKLİ KADAYİFCİ, EDA, HANÇERLİ TÖRÜN, SELDA, Yanartaş, Mehpare Sarı, Ergenç, Zeynep, SOMER, AYPER, DALKIRAN, TAHİR, ORBAK, ZERRİN, ELMAS BOZDEMİR, ŞEFİKA, Karbuz, Adem, Çiftdoğan, Dilek Yılmaz, and ANIL, AYŞE BERNA

Published
2020

47. Epidemiological, clinical, and laboratory features of children with COVID-19 in Turkey

Author

Aktürk, Hacer; Khalilova, Fidan; Çelikyurt, Aydın, Karbuz, Adem; Akkoç, Gülşen; Bedir Demirdağ, Tuğba; Yılmaz Çiftdoğan, Dilek; Özer, Arife; Çakır, Deniz; Hançerli Törün, Selda; Kepenekli, Eda; Erat, Tuğba; Dalgıç, Nazan; İlbay, Sare; Karaaslan, Ayşe; Erdeniz, Emine H.; Aygün, F. Deniz; Bozdemir, S. Elmas; Hatipoğlu, Nevin; Emiroğlu, Melike; Şahbudak Bal, Zümrüt; Çiftçi, Ergin; Bayhan, Gülsüm İclal; Gayretli Aydın, Zeynep Gökçe; Öcal Demir, Sevliya; Kılıç, Ömer; Hacımustafaoğlu, Mustafa; Şener Okur, Dicle; Şen, Semra; Yahşi, Aysun; Çetin, Benhur; Sütçü, Murat; Kara, Manolya; Uygun, Hatice; Tural Kara, Tuğçe; Korukluoğlu, Gülay; Akgün, Özlem; Üstündağ, Gülnihan; Demir Mis, Mevsim; Salı, Enes; Kaba, Özge; Yakut, Nurhayat; Kılıç, Orhan; Kanık, M. Kemal; Çetin, Ceren; Dursun, Adem; Çiçek, Muharrem; Koçkuzu, Esra; Şevketoğlu, Esra; Alkan, Gülsüm; Güner Özenen, Gizem; İnce, Erdal; Baydar, Zekiye; Özkaya, Ahmet Kağan; Ovalı, Hüsnü Fahri; Tekeli, Seher; Çelebi, Solmaz; Çubukçu, Birgül; Bal, Alkan; Köse, Mehmet; Hatipoğlu, Halil Uğur; Dalkıran, Tahir; Turgut, Mehmet; Başak Altaş, Ayşe; Selçuk Duru, Hatice Nilgün; Aksay, Ahu; Sağlam, Sevcan; Sarı Yanartaş, Mehpare; Ergenç, Zeynep; Akın, Yasemin; Düzenli Kar, Yeter; Şahin, Sabit; Tüter Öz, Şadiye Kübra; Bilen, Nimet Melis; Özdemir, Halil; Şenoglu, Mine Çiğdem; Parıltan Küçükalioğlu, Burcu; Besli, Gülser Esen; Kara, Yalçın; Turan, Cansu; Selbest Demirtaş, Burcu; Coşgun, Yasemin; Elevli, Murat; Şahin, Aslıhan; Bahtiyar Oğuz, Şerife; Somer, Ayper; Karadağ, Bülent; Demirhan, Recep; Türk Dağı, Hatice; Kurugöl, Zafer; Taşkın, Esra Çakmak; Şahiner, Ayşegül; Yeşil, Edanur; Ekemen Keleş, Yıldız; Sarıkaya, Remzi; Erdem Eralp, Ela; Özkınay, Ferda; Konca, Hatice Kübra; Yılmaz, Songül; Gökdemir, Yasemin; Arga, Gül; Özen, Seval; Çoksüer, Fevziye; Vatansever, Göksel; Tezer, Hasan; Kara, Ateş, Aktürk, Hacer; Khalilova, Fidan; Çelikyurt, Aydın, and Karbuz, Adem; Akkoç, Gülşen; Bedir Demirdağ, Tuğba; Yılmaz Çiftdoğan, Dilek; Özer, Arife; Çakır, Deniz; Hançerli Törün, Selda; Kepenekli, Eda; Erat, Tuğba; Dalgıç, Nazan; İlbay, Sare; Karaaslan, Ayşe; Erdeniz, Emine H.; Aygün, F. Deniz; Bozdemir, S. Elmas; Hatipoğlu, Nevin; Emiroğlu, Melike; Şahbudak Bal, Zümrüt; Çiftçi, Ergin; Bayhan, Gülsüm İclal; Gayretli Aydın, Zeynep Gökçe; Öcal Demir, Sevliya; Kılıç, Ömer; Hacımustafaoğlu, Mustafa; Şener Okur, Dicle; Şen, Semra; Yahşi, Aysun; Çetin, Benhur; Sütçü, Murat; Kara, Manolya; Uygun, Hatice; Tural Kara, Tuğçe; Korukluoğlu, Gülay; Akgün, Özlem; Üstündağ, Gülnihan; Demir Mis, Mevsim; Salı, Enes; Kaba, Özge; Yakut, Nurhayat; Kılıç, Orhan; Kanık, M. Kemal; Çetin, Ceren; Dursun, Adem; Çiçek, Muharrem; Koçkuzu, Esra; Şevketoğlu, Esra; Alkan, Gülsüm; Güner Özenen, Gizem; İnce, Erdal; Baydar, Zekiye; Özkaya, Ahmet Kağan; Ovalı, Hüsnü Fahri; Tekeli, Seher; Çelebi, Solmaz; Çubukçu, Birgül; Bal, Alkan; Köse, Mehmet; Hatipoğlu, Halil Uğur; Dalkıran, Tahir; Turgut, Mehmet; Başak Altaş, Ayşe; Selçuk Duru, Hatice Nilgün; Aksay, Ahu; Sağlam, Sevcan; Sarı Yanartaş, Mehpare; Ergenç, Zeynep; Akın, Yasemin; Düzenli Kar, Yeter; Şahin, Sabit; Tüter Öz, Şadiye Kübra; Bilen, Nimet Melis; Özdemir, Halil; Şenoglu, Mine Çiğdem; Parıltan Küçükalioğlu, Burcu; Besli, Gülser Esen; Kara, Yalçın; Turan, Cansu; Selbest Demirtaş, Burcu; Coşgun, Yasemin; Elevli, Murat; Şahin, Aslıhan; Bahtiyar Oğuz, Şerife; Somer, Ayper; Karadağ, Bülent; Demirhan, Recep; Türk Dağı, Hatice; Kurugöl, Zafer; Taşkın, Esra Çakmak; Şahiner, Ayşegül; Yeşil, Edanur; Ekemen Keleş, Yıldız; Sarıkaya, Remzi; Erdem Eralp, Ela; Özkınay, Ferda; Konca, Hatice Kübra; Yılmaz, Songül; Gökdemir, Yasemin; Arga, Gül; Özen, Seval; Çoksüer, Fevziye; Vatansever, Göksel; Tezer, Hasan; Kara, Ateş

Abstract

Objectives: the aim of this study is to identify the epidemiological, clinical, and laboratory features of coronavirus disease 2019 (COVID-19) in children.Methods: a retrospective study was conducted by pediatric infectious disease specialists from 32 different hospitals from all over Turkey by case record forms. Pediatric cases who were diagnosed as COVID-19 between March 16, 2020, and June 15, 2020 were included. Case characteristics including age, sex, dates of disease onset and diagnosis, family, and contact information were recorded. Clinical data, including the duration and severity of symptoms, were also collected. Laboratory parameters like biochemical tests and complete blood count, chest X-ray, and chest computed tomography (CT) were determined. Results: there were 1,156 confirmed pediatric COVID-19 cases. In total, male cases constituted 50.3% (n = 582) and females constituted 49.7% (n = 574). The median age of the confirmed cases was 10.75 years (4.5-14.6). Of the total cases, 90 were younger than 1 year of age (7.8%), 108 were 1-3 years of age (9.3%), 148 were 3-6 years of age (12.8%), 298 were 6-12 years of age (25.8%), 233 were 12-15 years of age (20.2%), and 268 cases were older than 15 years of age (23.2%). The most common symptom of the patients at the first visit was fever (50.4%) (n = 583) for a median of 2 days (IQR: 1-3 days). Fever was median at 38.4 degrees C (38.0-38.7 degrees C). The second most common symptom was cough (n = 543, 46.9%). The other common symptoms were sore throat (n = 143, 12.4%), myalgia (n = 141, 12.2%), dyspnea (n = 118, 10.2%), diarrhea (n = 112, 9.7%), stomachache (n = 71, 6.1%), and nasal discharge (n = 63, 5.4%). When patients were classified according to disease severity, 263 (22.7%) patients were asymptomatic, 668 (57.7%) patients had mild disease, 209 (18.1%) had moderate disease, and 16 (1.5%) cases had severe disease. One hundred and forty-nine (12.9%) cases had underlying diseases among the total cases; 56% of

Published
2021

48. Epidemiological, Clinical, and Laboratory Features of Children With COVID-19 in Turkey

Author

Karbuz, Adem, primary, Akkoc, Gulsen, additional, Bedir Demirdag, Tugba, additional, Yilmaz Ciftdogan, Dilek, additional, Ozer, Arife, additional, Cakir, Deniz, additional, Hancerli Torun, Selda, additional, Kepenekli, Eda, additional, Erat, Tugba, additional, Dalgic, Nazan, additional, Ilbay, Sare, additional, Karaaslan, Ayse, additional, Erdeniz, Emine H., additional, Aygun, F. Deniz, additional, Bozdemir, S. Elmas, additional, Hatipoglu, Nevin, additional, Emiroglu, Melike, additional, Sahbudak Bal, Zumrut, additional, Ciftci, Ergin, additional, Bayhan, Gulsum Iclal, additional, Gayretli Aydin, Zeynep Gokce, additional, Ocal Demir, Sevliya, additional, Kilic, Omer, additional, Hacimustafaoglu, Mustafa, additional, Sener Okur, Dicle, additional, Sen, Semra, additional, Yahsi, Aysun, additional, Akturk, Hacer, additional, Cetin, Benhur, additional, Sutcu, Murat, additional, Kara, Manolya, additional, Uygun, Hatice, additional, Tural Kara, Tugce, additional, Korukluoglu, Gulay, additional, Akgun, Ozlem, additional, Üstündağ, Gülnihan, additional, Demir Mis, Mevsim, additional, Sali, Enes, additional, Kaba, Ozge, additional, Yakut, Nurhayat, additional, Kılıc, Orhan, additional, Kanik, M. Kemal, additional, Cetin, Ceren, additional, Dursun, Adem, additional, Cicek, Muharrem, additional, Kockuzu, Esra, additional, Sevketoglu, Esra, additional, Alkan, Gulsum, additional, Guner Ozenen, Gizem, additional, İnce, Erdal, additional, Baydar, Zekiye, additional, Ozkaya, Ahmet Kagan, additional, Ovali, Husnu Fahri, additional, Tekeli, Seher, additional, Celebi, Solmaz, additional, Cubukcu, Birgul, additional, Bal, Alkan, additional, Khalilova, Fidan, additional, Kose, Mehmet, additional, Hatipoglu, Halil Ugur, additional, Dalkiran, Tahir, additional, Turgut, Mehmet, additional, Basak Altas, Ayse, additional, Selcuk Duru, Hatice Nilgün, additional, Aksay, Ahu, additional, Saglam, Sevcan, additional, Sari Yanartas, Mehpare, additional, Ergenc, Zeynep, additional, Akin, Yasemin, additional, Duzenli Kar, Yeter, additional, Sahin, Sabit, additional, Tuteroz, Sadiye Kubra, additional, Bilen, Nimet Melis, additional, Ozdemir, Halil, additional, Senoglu, Mine Cidem, additional, Pariltan Kucukalioglu, Burcu, additional, Besli, Gulser Esen, additional, Kara, Yalcin, additional, Turan, Cansu, additional, Selbest Demirtas, Burcu, additional, Celikyurt, Aydın, additional, Cosgun, Yasemin, additional, Elevli, Murat, additional, Sahin, Aslihan, additional, Bahtiyar Oguz, Serife, additional, Somer, Ayper, additional, Karadag, Bulent, additional, Demirhan, Recep, additional, Turk Dagi, Hatice, additional, Kurugol, Zafer, additional, Taskin, Esra Cakmak, additional, Sahiner, Aysegul, additional, Yesil, Edanur, additional, Ekemen Keles, Yildiz, additional, Sarikaya, Remzi, additional, Erdem Eralp, Ela, additional, Ozkinay, Ferda, additional, Konca, Hatice Kubra, additional, Yilmaz, Songul, additional, Gokdemir, Yasemin, additional, Arga, Gul, additional, Ozen, Seval, additional, Coksuer, Fevziye, additional, Vatansever, Goksel, additional, Tezer, Hasan, additional, and Kara, Ates, additional

Published
2021
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