727 results on '"Akova, Murat"'
Search Results
2. Effect of therapeutic plasma exchange on antimicrobials in critically ill patients
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Balaban, Ugur, Kara, Emre, Kaya, Esat Kivanc, Ozcebe, Osman Ilhami, Akova, Murat, Topeli, Arzu, Yorganci, Kaya, and Demirkan, Kutay
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- 2024
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3. Hospital-acquired bloodstream infections in critically ill cirrhotic patients: a post-hoc analysis of the EUROBACT-2 international cohort study
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Wozniak, Hannah, Tabah, Alexis, Barbier, François, Ruckly, Stéphane, Loiodice, Ambre, Akova, Murat, Leone, Marc, Conway Morris, Andrew, Bassetti, Matteo, Arvaniti, Kostoula, Ferrer, Ricard, de Bus, Liesbet, Paiva, Jose Artur, Bracht, Hendrik, Mikstacki, Adam, Alsisi, Adel, Valeanu, Liana, Prazak, Josef, Timsit, Jean-François, and Buetti, Niccolò
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- 2024
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4. Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM
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Bassetti, Matteo, Giacobbe, Daniele R., Agvald-Ohman, Christina, Akova, Murat, Alastruey-Izquierdo, Ana, Arikan-Akdagli, Sevtap, Azoulay, Elie, Blot, Stijn, Cornely, Oliver A., Cuenca-Estrella, Manuel, de Lange, Dylan W., De Rosa, Francesco G., De Waele, Jan J., Dimopoulos, George, Garnacho-Montero, Jose, Hoenigl, Martin, Kanj, Souha S., Koehler, Philipp, Kullberg, Bart J., Lamoth, Frédéric, Lass-Flörl, Cornelia, Maertens, Johan, Martin-Loeches, Ignacio, Muñoz, Patricia, Poulakou, Garyphallia, Rello, Jordi, Sanguinetti, Maurizio, Taccone, Fabio S., Timsit, Jean-François, Torres, Antoni, Vazquez, Jose A., Wauters, Joost, Asperges, Erika, Cortegiani, Andrea, Grecchi, Cecilia, Karaiskos, Ilias, Le Bihan, Clément, Mercier, Toine, Mortensen, Klaus L., Peghin, Maddalena, Rebuffi, Chiara, Tejada, Sofia, Vena, Antonio, Zuccaro, Valentina, Scudeller, Luigia, and Calandra, Thierry
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- 2024
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5. Correction: The role of centre and country factors on process and outcome indicators in critically ill patients with hospital-acquired bloodstream infections
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Buetti, Niccolò, Tabah, Alexis, Setti, Nour, Ruckly, Stéphane, Barbier, François, Akova, Murat, Aslan, Abdullah Tarik, Leone, Marc, Bassetti, Matteo, Morris, Andrew Conway, Arvaniti, Kostoula, Paiva, José-Artur, Ferrer, Ricard, Qiu, Haibo, Montrucchio, Giorgia, Cortegiani, Andrea, Kayaaslan, Bircan, De Bus, Liesbet, De Waele, Jan J., and Timsit, Jean-François
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- 2024
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6. Attributable mortality of candidemia – Results from the ECMM Candida III multinational European Observational Cohort Study
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Salmanton-García, Jon, Cornely, Oliver A., Stemler, Jannik, Barać, Aleksandra, Steinmann, Jörg, Siváková, Alena, Akalin, Emin Halis, Arikan-Akdagli, Sevtap, Loughlin, Laura, Toscano, Cristina, Narayanan, Manjusha, Rogers, Benedict, Willinger, Birgit, Akyol, Deniz, Roilides, Emmanuel, Lagrou, Katrien, Mikulska, Malgorzata, Denis, Blandine, Ponscarme, Diane, Scharmann, Urlike, Azap, Alpay, Lockhart, Deborah, Bicanic, Tihana, Kron, Florian, Erben, Nurettin, Rautemaa-Richardson, Riina, Goodman, Anna L., Garcia-Vidal, Carolina, Lass-Flörl, Cornelia, Gangneux, Jean-Pierre, Taramasso, Lucia, Ruiz, Maite, Schick, Yael, Van Wijngaerden, Eric, Milacek, Christopher, Giacobbe, Daniele Roberto, Logan, Clare, Rooney, Emily, Gori, Andrea, Akova, Murat, Bassetti, Matteo, Hoenigl, Martin, and Koehler, Philipp
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- 2024
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7. Immunogenicity, reactogenicity, and safety of a second booster with BNT162b2 or full-dose mRNA-1273: A randomized VACCELERATE trial in adults aged ≥75 years (EU-COVAT-1-AGED Part B)
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Stemler, Jannik, Yeghiazaryan, Lusine, Stephan, Christoph, Mohn, Kristin Greve-Isdahl, Carcas-Sansuan, Antonio-José, Rodriguez, Esperanza Romero, Moltó, José, Mitxeltorena, Itziar Vergara, Welte, Tobias, Zablockienė, Birutė, Akova, Murat, Bethe, Ullrich, Heringer, Sarah, Salmanton-García, Jon, Jeck, Julia, Tischmann, Lea, Zarrouk, Marouan, Cüppers, Arnd, Biehl, Lena M., Grothe, Jan, Mellinghoff, Sibylle C., Nacov, Julia A., Neuhann, Julia M., Sprute, Rosanne, Frías-Iniesta, Jesús, Negi, Riya, Gaillard, Colette, Saini, Gurvin, León, Alejandro García, Mallon, Patrick W.G., Lammens, Christine, Hotterbeekx, An, Loens, Katherine, Malhotra-Kumar, Surbhi, Goossens, Herman, Kumar-Singh, Samir, König, Franz, Posch, Martin, Koehler, Philipp, and Cornely, Oliver A.
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- 2024
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8. Effect of adequacy of empirical antibiotic therapy for hospital-acquired bloodstream infections on intensive care unit patient prognosis: a causal inference approach using data from the Eurobact2 study
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Tabah, Alexis, Lipman, Jeffrey, Pollock, Hamish, Ben Margetts, Udy, Andrew, Young, Meredith, Bhadange, Neeraj, Tyler, Steven, Ledtischke, Anne, Finnis, Mackenzie, Dwivedi, Jyotsna, Saxena, Manoj, Biradar, Vishwanath, Soar, Natalie, Sarode, Vineet, Brewster, David, Regli, Adrian, Weeda, Elizabeth, Ahmed, Samiul, Fourie, Cheryl, Laupland, Kevin, Ramanan, Mahesh, Walsham, James, Meyer, Jason, Litton, Edward, Maria Palermo, Anna, Yap, Timothy, Eroglu, Ege, George Attokaran, Antony, Jaramillo, C'havala, Nafees, Khalid Mk, Nafees, Khalid Mahmood Khan, Aqilah Haji Abd Rashid, Nurhikmahtul, Adi Muhamad Ibnu Walid, Haji, Mon, Tomas, Dhakshina Moorthi, P., Sudhirchandra, Shah, Sridharan, Dhadappa Damodar, Haibo, Qiu, Xie, Jianfeng, Jianfeng, Xie, Wei-Hua, Lu, Zhen, Wang, Qian, Chuanyun, Luo, Jili, Chen, Xiaomei, Wang, Hao, Zhao, Peng, Zhao, Juan, Wusi, Qiu, Mingmin, Chen, Xu, Lei, Yin, Chengfen, Wang, Ruilan, Wang, Jinfeng, Yin, Yongjie, Zhang, Min, Ye, Jilu, Hu, Chungfang, Zhou, Suming, Huang, Min, Yan, Jing, Wang, Yan, Qin, Bingyu, Ye, Ling, Weifeng, Xie, Peije, Li, Geng, Nan, Ling, Lowell, Hayashi, Yoshiro, Karumai, Toshiyuki, Yamasaki, Masaki, Hashimoto, Satoru, Hosokawa, Koji, Makino, Jun, Matsuyoshi, Takeo, Kuriyama, Akira, Shigemitsu, Hidenobu, Mishima, Yuka, Nagashima, Michio, Yoshida, Hideki, Fujitani, Shigeki, Omori, Koichiro, Rinka, Hiroshi, Saito, Hiroki, Atobe, Kaori, Kato, Hideaki, Takaki, Shunsuke, Sulaiman, Helmi, Shahnaz Hasan, M., Fadhil Hadi Jamaluddin, Muhamad, Pheng, Lee See, Visvalingam, Sheshendrasurian, Thing Liew, Mun, Ling Danny Wong, Siong, Khang Fong, Kean, Bt Abdul Rahman, Hamizah, Md Noor, Zuraini, Lee, Kok Tong, Hamid Azman, Abd., Zulfakar Mazlan, Mohd, Ali, Saedah, Hernandez, Aaron Mark, Abello, Anton, Jeon, Kyeongman, Lee, Sang-Min, Park, Sunghoon, Park, Seung Yong, Yoon Lim, Sung, Kwa, Andrea Lay Hoon, Yuan Goh, Qing, Ng, Shin Yi, An Lie, Sui, Junyang Goh, Ken, Yunkai Li, Andrew, Ong, Caroline Yu Ming, Yan Lim, Jia, Lishan Quah, Jessica, Ng, Kangqi, Xiang Long Ng, Louis, Yeh, Tony Yu-Chang, Chang Yeh, Yu, Chou, Nai-Kuan, Cia, Cong-Tat, Hu, Ting-Yu, Kuo, Li-Kuo, Ku, Shih-Chi, Wongsurakiat, Phunsup, Apichatbutr, Yutthana, Chiewroongroj, Supattra, Alsisi, Adel, Nadeem, Rashid, El Houfi, Ashraf, Elhadidy, Amr, Barsoum, Mina, Osman, Nermin, Mostafa, Tarek, Elbahnasawy, Mohamed, Saber, Ahmed, Aldhalia, Amer, Elmandouh, Omar, Elsayed, Ahmed, Elbadawy, Merihan A., Awad, Ahmed K., Hemead, Hanan M., Zand, Farid, Ouhadian, Maryam, Hamid Borsi, Seyed, Mehraban, Zahra, Kashipazha, Davood, Ahmadi, Fatemeh, Savaie, Mohsen, Soltani, Farhad, Rashidi, Mahboobeh, Baghbanian, Reza, Javaherforoosh, Fatemeh, Amiri, Fereshteh, Kiani, Arash, Amin Zargar, Mohammad, Mahmoodpoor, Ata, Aalinezhad, Fatemeh, Dabiri, Gholamreza, Sabetian, Golnar, Sarshad, Hakimeh, Masjedi, Mansoor, Tajvidi, Ramin, Nasirodin (S.M.N.) Tabatabaei, Dr Seyed Mohammad, Ahmed, Abdullah Khudhur, Singer, Pierre, Kagan, Ilya, Rigler, Merav, Belman, Daniel, Levin, Phillip, Harara, Belal, Diab, Adei, Abillama, Fayez, Abilama, Fayez, Ibrahim, Rebecca, Fares, Aya, Elhadi, Muhammed, Buimsaedah, Ahmad, Gamra, Marwa, Aqeelah, Ahmed, Ali Mohammed Ali, Almajdoub, Gaber Sadik Homaidan, Ahmed, Almiqlash, Bushray, Bilkhayr, Hala, Bouhuwaish, Ahmad, Sa Taher, Ahmed, Abdulwahed, Eman, Abousnina, Fathi A., Khaled Hdada, Aisha, Jobran, Rania, Ben Hasan, Hayat, Shaban Ben Hasan, Rabab, Khalid Abidi, Serghini, Issam, Seddiki, Rachid, Boukatta, Brahim, Kanjaa, Nabil, Mouhssine, Doumiri, Ahmed Wajdi, Maazouzi, Dendane, Tarek, Ali Zeggwagh, Amine, Housni, Brahim, Younes, Oujidi, Hachimi, Abdelhamid, Ghannam, A., Belkhadir, Z., Abu Jayyab, Mustafa, Aithssain, Ali, Lance, Marcus, Nissar, Shaikh, Sallam, Hend, Elrabi, Omar, Almekhlafi, Ghaleb A., Awad, Maher, Aljabbary, Ahmed, Karam Chaaban, Mohammad, Abu-Sayf, Natalia, Al-Jadaan, Mohammad, Bakr, Lubna, Mounir Bouaziz, Bouaziz, Mounir, Turki, Olfa, Sellami, Walid, Vidal, Gabriela, Centeno, Pablo, Morvillo, Natalia, Oscar Acevedo, José, Mabel Lopez, Patricia, Fernández, Rubén, Segura, Matías, Aparicio, Marta, Alonzo, Irene, Nuccetelli, Yanina, Montefiore, Pablo, Arias, Mario, Felipe Reyes, Luis, Ñamendys-Silva, Silvio A., Romero-Gonzalez, Juan P., Hermosillo, Mariana, Alejandro Castillo, Roberto, Nicolás Pantoja Leal, Jesús, Garcia Aguilar, Candy, Ocotlan Gonzalez Herrera, Mara, Vladimir Espinoza Villafuerte, Missael, Lomeli-Teran, Manuel, Dominguez-Cherit, Jose G., Davalos-Alvarez, Adrian, Sánchez-Hurtado, Luis, Tejeda-Huezo, Brigitte, Perez-Nieto, Orlando R., Deloya Tomas, Ernesto, De Bus, Liesbet, De Waele, Jan, Francois, Guy, Hollevoet, Isabelle, Denys, Wouter, Bourgeois, Marc, Vanderhaeghen, Sofie F.M., Mesland, Jean-Baptiste, Henin, Pierre, Haentjens, Lionel, Biston, Patrick, Noel, Cindérella, Layos, Nathalie, Misset, Benoît, De Schryver, Nicolas, Serck, Nicolas, Wittebole, Xavier, De Waele, Elisabeth, Opdenacker, Godelive, Kovacevic, Pedja, Zlojutro, Biljana, Ina, Filipovic-Grcic, Custovic, Aida, Filipovic-Grcic, Ina, Radonic, Radovan, Vujaklija Brajkovic, Ana, Persec, Jasminka, Sakan, Sanja, Nikolic, Mario, Lasic, Hrvoje, Leone, Marc, Timsit, Jean-François, Ruppe, Etienne, Ruckly, Stephane, Montravers, Philippe, Arbelot, Charlotte, Patrier, Juliette, Zappela, N., Montravers, P., Dulac, Thierry, Castanera, Jérémy, Auchabie, Johann, Le Meur, Anthony, Marchalot, A., Beuzelin, M., Massri, Alexandre, Guesdon, Charlotte, Escudier, Etienne, Mateu, Philippe, Rosman, Jérémy, Leroy, Olivier, Alfandari, Serge, Nica, Alexandru, Souweine, Bertrand, Coupez, Elisabeth, Duburcq, Thibault, Kipnis, Eric, Bortolotti, Perrine, Le Souhaitier, Mathieu, Mira, Jean-Paul, Garcon, Pierre, Duprey, Matthieu, Thyrault, Martial, Paulet, Rémi, Philippart, François, Tran, Marc, Bruel, Cédric, Weiss, Emmanuel, Janny, Sylvie, Foucrier, Arnaud, Perrigault, Pierre-François, Djanikian, Flora, Barbier, François, Gainnier, Marc, Bourenne, Jérémy, Louis, Guillaume, Smonig, Roland, Argaud, Laurent, Baudry, Thomas, Mekonted Dessap, Armand, Razazi, Keyvan, Kalfon, Pierre, Badre, Gaëtan, Larcher, Romaric, Lefrant, Jean-Yves, Roger, Claire, Sarton, Benjamine, Silva, Stein, Demeret, Sophie, Le Guennec, Loïc, Siami, Shidasp, Aparicio, Christelle, Voiriot, Guillaume, Fartoukh, Muriel, Dahyot-Fizelier, Claire, Imzi, Nadia, Klouche, Kada, Bracht, Hendrik, Hoheisen, Sandra, Bloos, Frank, Thomas-Rueddel, Daniel, Petros, Sirak, Pasieka, Bastian, Dubler, Simon, Schmidt, Karsten, Gottschalk, Antje, Wempe, Carola, Lepper, Philippe, Metz, Carlos, Viderman, Dmitriy, Umbetzhanov, Yerlan, Mugazov, Miras, Bazhykayeva, Yelena, Kaligozhin, Zhannur, Babashev, Baurzhan, Merenkov, Yevgeniy, Temirov, Talgat, Arvaniti, Kostoula, Smyrniotis, Dimitrios, Psallida, Vasiliki, Fildisis, Georgios, Soulountsi, Vasiliki, Kaimakamis, Evangelos, Iasonidou, Cristina, Papoti, Sofia, Renta, Foteini, Vasileiou, Maria, Romanou, Vasiliki, Koutsoukou, Vasiliki, Kristina Matei, Mariana, Moldovan, Leora, Karaiskos, Ilias, Paskalis, Harry, Marmanidou, Kyriaki, Papanikolaou, M., Kampolis, C., Oikonomou, Marina, Kogkopoulos, Evangelos, Nikolaou, Charikleia, Sakkalis, Anastasios, Chatzis, Marinos, Georgopoulou, Maria, Efthymiou, Anna, Chantziara, Vasiliki, Sakagianni, Aikaterini, Athanasa (Athanassa), Zoi (Zoe), Papageorgiou, Eirini, Ali, Fadi, Dimopoulos, Georges, Panagiota Almiroudi, Mariota, Malliotakis, Polychronis, Marouli, Diamantina, Theodorou, Vasiliki, Retselas, Ioannis, Kouroulas, Vasilios, Papathanakos, Georgios, Bassetti, Matteo, Giacobbe, Daniele, Montrucchio, Giorgia, Sales, Gabriele, De Pascale, Gennaro, Maria Montini, Luca, Carelli, Simone, Vargas, Joel, Di Gravio, Valentina, Roberto Giacobbe, Daniele, Gratarola, Angelo, Porcile, Elisa, Mirabella, Michele, Daroui, Ivan, Lodi, Giovanni, Zuccaro, Francesco, Grazia Schlevenin, Maria, Pelosi, Paolo, Battaglini, Denise, Cortegiani, Andrea, Ippolito, Mariachiara, Bellina, Davide, Di Guardo, Andrea, Pelagalli, Lorella, Covotta, Marco, Rocco, Monica, Fiorelli, Silvia, Cotoia, Antonella, Chiara Rizzo, Anna, Adam Mikstacki, Mikstacki, Adam, Tamowicz, Barbara, Kaptur Komorowska, Irmina, Szczesniak, Anna, Bojko, Jozef, Kotkowska, Anna, Walczak-Wieteska, Paulina, Wasowska, Dominika, Nowakowski, Tomasz, Broda, Hanna, Mariusz Peichota, Assoc, Pietraszek-Grzywaczewska, Iwona, Martin-Loeches, Ignacio, Bisanti, Alessandra, Paiva, José Artur, Póvoa, Pedro, Cartoze, Nuno, Pereira, Tiago, Guimarães, Nádia, Alves, Madalena, Josefina Pinheiro Marques, Ana, Rios Pinto, Ana, Krystopchuk, Andriy, Teresa, Ana, Manuel Pereira de Figueiredo, António, Botelho, Isabel, Duarte, Tiago, Costa, Vasco, Pedro Cunha, Rui, Molinos, Elena, Tito da Costa, Ledo, Sara, Queiró, Joana, Pascoalinho, Dulce, Nunes, Cristina, Pedro Moura, José, Pereira, Énio, Carvalho Mendes, António, Valeanu, Liana, Bubenek-Turconi, Serban, Marina Grintescu, Ioana, Cobilinschi, Cristian, Carmen Filipescu, Daniela, Elena Predoi, Cornelia, Tomescu, Dana, Popescu, Mihai, Marcu, Alexandra, Grigoras, Ioana, Lungu, Olguta, Gritsan, Alexey, Anderzhanova, Anastasia, Meleshkina, Yulia, Magomedov, Marat, Zubareva, Nadezhda, Tribulev, Maksim, Gaigolnik, Denis, Eremenko, Aleksandr, Vistovskaya, Natala, Chukina, Maria, Belskiy, Vladislav, Furman, Mikhail, Ferrer Rocca, Ricard, Martinez, Maria, Casares, Vanessa, Mellado Artigas, Ricard, Vera, Paula, Flores, Matias, Amador Amerigo, Joaquin, Gracia Arnillas, Maria Pilar, Munoz Bermudez, Rosana, Armestar, Fernando, Catalan, Beatriz, Roig, Regina, Raguer, Laura, Dolores Quesada, María, Diaz Santos, Emilio, Gomà, Gemma, Ubeda, Alejandro, Salgado, Maria, Forcelledo Espina, Lorena, Garcia Prieto, Emilio, Asensio, Mj, Rodriguez, M., Maseda, Dr Emilio, Suarez De La Rica, Alejandro, Ignacio Ayestaran, J., Novo, Mariana, Blasco-Navalpotro, Miguel Angel, Orejas Gallego, Alberto, Sjovall, Fredrik, Sjövall, Fredrik, Spahic, Dzana, Johan Svensson, Carl, Haney, Michael, Edin, Alicia, Åkerlund, Joyce, De Geer, Lina, Prazak, Josef, Buetti, Niccolò, Jakob, Stephan, Pagani, Jl, Abed-Maillard, S., Akova, Murat, Aslan, Abdullah Tarık, Aslan, Abdullah Tarik, Timuroglu, Arif, Kocagoz, Sesin, Kusoglu, Hulya, Mehtap, Selcuk, Ceyhun, Solakoğlu, Altintas, Dr. Neriman Defne, Talan, Leyla, Kayaaslan, Bircan, Kaya Kalem, Ayşe, Kurt, Dr. Ibrahim, Telli, Murat, Ozturk, Barcin, Erol, Çiğdem, Dindar Demiray, Emine Kubra, Çolak, Sait, Akbas, Türkay, Dr. Kursat Gundogan, Sari, Ali, Agalar, Canan, Çolak, Onur, Baykam, Nurcan (N), Akdogan, Ozlem (O), Yilmaz, Mesut, Tunay, Burcu, Cakmak, Rumeysa, Saltoglu, Nese, Karaali, Ridvan, Iftihar Koksal, Firdevs Aksoy, Eroglu, Ahmet, Tolga Saracoglu, Kemal, Bilir, Yeliz, Guzeldag, Seda, Ersoz, Gulden, Evik, Guliz, Sungurtekin, Hulya, Ozgen, Cansu, Erdoğan, Cem, Gürbüz, Yunus, Altin, Nilgün, Bayindir, Yasar, Ersoy, Yasemin, Goksu, Senay, Akyol, Ahmet, Dr, Kartal, Batirel, Ayse, Cagan Aktas, Sabahat, Morris, Andrew Conway, Conway Morris, Andrew, Routledge, Matthew, Ercole, Ari, Antcliffe, David, Rojo, Roceld, Tizard, Kate, Faulkner, Maria, Cowton, Amanda, Kent, Melanie, Raj, Ashok, Zormpa, Artemis, Tinaslanidis, George, Khade, Reena, Torlinski, Tomasz, Mulhi, Randeep, Goyal, Shraddha, Bajaj, Manan, Soltan, Marina, Yonan, Aimee, Dolan, Rachael, Johnson, Aimee, Macfie, Caroline, Lennard, James, Templeton, Maie, Sousa Arias, Sonia, Franke, Uwe, Hugill, Keith, Angell, Hollie, Benjamin J Parcell, Cobb, Katherine, Cole, Stephen, Smith, Tim, Graham, Clive, Cerman, Jaroslav, Keegan, Allison, Ritzema, Jenny, Sanderson, Amanda, Roshdy, Ashraf, Szakmany, Tamas, Baumer, Tom, Longbottom, Rebecca, Hall, Daniel, Tatham, Kate, Loftus, S., Husain, A., Black, E., Jhanji, S., Rao Baikady, R., Mcguigan, Peter, Mckee, Rachel, Kannan, Santhana, Antrolikar, Supriya, Marsden, Nicholas, Della Torre, Valentina, Banach, Dorota, Zaki, Ahmed, Jackson, Matthew, Chikungwa, Moses, Attwood, Ben, Patel, Jamie, Rebecca E Tilley, Humphreys, Sally K., Jean Renaud, Paul, Sokhan, Anton, Burma, Yaroslava, Sligl, Wendy, Baig, Nadia, McCoshen, Lorena, Kutsogiannis, Demetrios J., Thompson, Patricia, Hewer, Tayne, Rabbani, Raihan, Huq, Shihan Mahmud Redwanul, Hasan, Rajib, Motiul Islam, Mohammad, Gurjar, Mohan, Baronia, Arvind, Kothari, Nikhil, Sharma, Ankur, Karmakar, Saurabh, Sharma, Priya, Nimbolkar, Janardan, Samdani, Pratit, Vaidyanathan, R., Ahmedi Rubina, Noor, Jain, Nikhilesh, Pahuja, Madhumati, Singh, Ritu, Shekhar, Saurav, Syed, Nabeel Muzaffar, Ozair, Ahmad, Sarwar Siddiqui, Suhail, Bose, Payel, Datta, Avijatri, Rathod, Darshana, Patel, Mayur, MK, Renuka, Sailaja, K Baby, Dsilva, Carol, Chandran, Jagadish, Ghosh, Pralay, Mukherjee, Sudipta, Sheshala, Kaladhar, Chandra Misra, Krushna, Adekola, Oyebola O., Yusuf Yakubu, Saidu, Mgbosoro Ugwu, Euphemia, Olatosi, John (O), Desalu, Ibironke, Asiyanbi, Gabriel, Oladimeji, Motunrayo, Idowu, Olusola, Adeola, Fowotade, Mer, Mervyn, Mc Cree, Melanie, El Sanousi, Dr. Bashir, Adil Ali Karar, Ali, Saidahmed, Elfayadh, Hamid, Hytham K.S., Loiodice, Ambre, Bailly, Sébastien, Ruckly, Stéphane, and Staiquly, Quentin
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- 2024
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9. Human memory T cell dynamics after aluminum-adjuvanted inactivated whole-virion SARS-CoV-2 vaccination
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Tavukcuoglu, Ece, Yanik, Hamdullah, Parveen, Mubaida, Uluturk, Sila, Durusu-Tanriover, Mine, Inkaya, Ahmet Cagkan, Akova, Murat, Unal, Serhat, and Esendagli, Gunes
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- 2023
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10. Attributable mortality of infections caused by carbapenem-resistant Enterobacterales: results from a prospective, multinational case-control-control matched cohorts study (EURECA)
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Serna, Almudena de la, Monteau, Sophie, Palomo, Virginia, Soriano, Elena, Gutierrez, David, Moreno, Elisa, Sojo-Dorado, Jesus, Morales, Isabel, Maldonado, Natalia, Santis, Lucia Valiente de, Ciezar, Antonio Plata, Ruiz Mesa, Juan Diego, Diaz, Beatriz Sobrino, Gomez, Ignacio Marquez, Camacho, Ines Perez, Cano, Angela, Frutos-Adame, Azahara, Guzman-Puche, Julia, Gracia-Ahufinger, Irene, Perez-Nadales, Elena, Torre-Gimenez, Julian, Pyrpasopoulou, Athina, Iosifidis, Elias, Chorafa, Elsa, Radovanovic, Ivana, Petrovic, Sladjana, Cvetkovi, Slavica, Melentijevic, Srdjan-Sanja, Bicmen, Can, Senol, Gunes, Tubau, Fe, Camara, Jordi, Daniel Gumucio, Victor, Bassoulis, Dimitris, Deliolanis, John, Pitiriga, Vassiliki Ch., Triarides, Nikolaos, Argiti, Efstathia, Legakis, Nikolaos J., Margarita, Kyriakidou, Gijón-Cordero, Desirée, Ruiz-Garbajosa, Patricia, Rossolini, Gian Maria, Nica, Maria, Talapan, Daniela, Medić, Deana, Prijić, Sanja Maričić, Caballero, Mireia Cantero, Ramírez, Lina M Parra, Bilgin, Hüseyin, Dalekos, George N., Stefos, Aggelos, Spyridis, Nikolaos, Michos, Athanasios, De Rosa, Francesco Giuseppe, Cavallo, Rossana, Petrosillo, Nicola, Dicaro, Antonio, Landini, Maria Paola, degli Atti, Marta Luisa Ciofi, Masanovic, Mileva, Matkovic, Dusan, Tsiodras, Sotirios, Blasi, Francesco, pasquale, Marta Di, Viscoli, Claudio, Vata, Andrei, Dorneanu, Olivia, Kapisyzi, Perlat, Vince, Adriana, Tsigou, Evdoxia, Maltezos, Efstratios, Komnos, Apostolos, Gogos, Charalampos, Franzetti, Fabio, Antonelli, Massimo, Lupse, Mihaela, Corneci, Dan, Tomescu, Dana, Georgescu, Anca, Bukarica, Ljiljana, Mitrović, Goran, Krstić, Nataša Lukić, Kurti, Arsim, Reuter, Sandra, Díaz-Pollán, Beatriz, Sabater, Julia Origüen, Muñoz, Patricia, Azap, Alpay, ancak, Banu, Sahin, Arife, Akalin, Halis, Paniagua-García, María, Bravo-Ferrer, Jose M., Pérez-Galera, Salvador, Kostyanev, Tomislav, de Kraker, Marlieke E.A., Feifel, Jan, Palacios-Baena, Zaira R., Schotsman, Joost, Cantón, Rafael, Daikos, George L., Carevic, Biljana, Dragovac, Gorana, Tan, Lionel K., Raka, Lul, Hristea, Adriana, Viale, Pierluigi, Akova, Murat, Cano, Ángela, Reguera, Jose María, Bartoloni, Alessandro, Florescu, Simin-Aysel, Benea, Serban, Asensio, Ángel, Korten, Volkan, Grundmann, Hajo, Goossens, Herman, Bonten, Marc J., Gutiérrez-Gutiérrez, Belén, and Rodríguez-Baño, Jesús
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- 2024
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11. Infectious diseases ethics: a worldwide survey
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Righi, Elda, Mirandola, Massimo, Grossi, Alessandra Agnese, Akova, Murat, Tacconelli, Evelina, Fratucello, Anna, Nasim, Asma, Barac, Aleksandra, and Yahav, Dafna
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- 2024
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12. Prevention and treatment of bacterial infections in patients with haematological cancers and haematopoietic stem cell transplantation: headways and shortcomings
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Er, Ahmet Görkem, Aslan, Abdullah Tarik, Mikulska, Malgorzata, and Akova, Murat
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- 2024
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13. Consensus position statement on advancing the standardised reporting of infection events in immunocompromised patients
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Teh, Benjamin W, Mikulska, Malgorzata, Averbuch, Dina, de la Camara, Rafael, Hirsch, Hans H, Akova, Murat, Ostrosky-Zeichner, Luis, Baddley, John W, Tan, Ban Hock, Mularoni, Alessandra, Subramanian, Aruna K, La Hoz, Ricardo M, Marinelli, Tina, Boan, Peter, Aguado, Jose Maria, Grossi, Paolo A, Maertens, Johan, Mueller, Nicolas J, and Slavin, Monica A
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- 2024
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14. Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study
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Tabah, Alexis, Buetti, Niccolò, Staiquly, Quentin, Ruckly, Stéphane, Akova, Murat, Aslan, Abdullah Tarik, and Leone, Marc
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Pfizer Inc. ,Medical research -- Analysis -- Health aspects ,Medicine, Experimental -- Analysis -- Health aspects ,Drug resistance in microorganisms -- Analysis -- Health aspects ,Pharmaceutical industry -- Health aspects -- Analysis ,Health care industry - Abstract
Purpose In the critically ill, hospital-acquired bloodstream infections (HA-BSI) are associated with significant mortality. Granular data are required for optimizing management, and developing guidelines and clinical trials. Methods We carried out a prospective international cohort study of adult patients ([greater than or equal to] 18 years of age) with HA-BSI treated in intensive care units (ICUs) between June 2019 and February 2021. Results 2600 patients from 333 ICUs in 52 countries were included. 78% HA-BSI were ICU-acquired. Median Sequential Organ Failure Assessment (SOFA) score was 8 [IQR 5; 11] at HA-BSI diagnosis. Most frequent sources of infection included pneumonia (26.7%) and intravascular catheters (26.4%). Most frequent pathogens were Gram-negative bacteria (59.0%), predominantly Klebsiella spp. (27.9%), Acinetobacter spp. (20.3%), Escherichia coli (15.8%), and Pseudomonas spp. (14.3%). Carbapenem resistance was present in 37.8%, 84.6%, 7.4%, and 33.2%, respectively. Difficult-to-treat resistance (DTR) was present in 23.5% and pan-drug resistance in 1.5%. Antimicrobial therapy was deemed adequate within 24 h for 51.5%. Antimicrobial resistance was associated with longer delays to adequate antimicrobial therapy. Source control was needed in 52.5% but not achieved in 18.2%. Mortality was 37.1%, and only 16.1% had been discharged alive from hospital by day-28. Conclusions HA-BSI was frequently caused by Gram-negative, carbapenem-resistant and DTR pathogens. Antimicrobial resistance led to delays in adequate antimicrobial therapy. Mortality was high, and at day-28 only a minority of the patients were discharged alive from the hospital. Prevention of antimicrobial resistance and focusing on adequate antimicrobial therapy and source control are important to optimize patient management and outcomes., Author(s): Alexis Tabah [sup.1] [sup.2] [sup.3] [sup.4], Niccolò Buetti [sup.5] [sup.6], Quentin Staiquly [sup.7], Stéphane Ruckly [sup.6] [sup.7], Murat Akova [sup.8], Abdullah Tarik Aslan [sup.9], Marc Leone [sup.10], Andrew Conway [...]
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- 2023
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15. Efficacy and safety of the siRNA JNJ-73763989 and the capsid assembly modulator JNJ-56136379 (bersacapavir) with nucleos(t)ide analogues for the treatment of chronic hepatitis B virus infection (REEF-1): a multicentre, double-blind, active-controlled, randomised, phase 2b trial
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Bourgeois, Stefan, Vanwolleghem, Thomas, Nevens, Frederik, Horsmans, Yves, Van Vlierberghe, Hans, Nastri, Ana Catharina, Lacerda, Marcus, Ramji, Alnoor, Conway, Brian, Coffin, Carla, Janssen, Harry, Fung, Scott, Shafran, Stephen, Hou, Jin Lin, Sperl, Jan, Urbanek, Petr, Plisek, Stanislav, Hejda, Vaclav, Samuel, Didier, Lacombe, Karine, Zoulim, Fabien, Guyader, Dominique, Raffi, Francois, Asselah, Tarik, Bourliere, Marc, Hilleret, Marie-Noelle, Wedemeyer, Heiner, Schulze zur Wiesch, Julian, Sprinzl, Kathrin, van Boemmel, Florian, Hilgard, Gudrun, Sabranski, Michael, Arasteh, Keikawus, Chan, Henry LY, Yuen, Man Fung, Wong, Vincent Ws, Brunetto, Maurizia Rossana, Taliani, Gloria, Andreone, Pietro, Lampertico, Pietro, Kurosaki, Masayuki, Yatsuhashi, Hiroshi, Fujiwara, Kei, Takehara, Tetsuo, Kawaoka, Tomokazu, Asahina, Yasuhiro, Enomoto, Hirayuki, Yabushita, Kazuhisa, Notsumata, Kazuo, Takaguchi, Koichi, Kawabe, Naoto, Kato, Naoya, Koji, Ogawa, Namisaki, Tadashi, Suzuki, Yoshiyuki, Yoon, Jung-Hwan, Ahn, SangHoon, Lim, Young-Suk, Paik, Seung Woon, Kiew, Kuang Kiat, Mohamed, Rosmawati, Tan, Soek Siam, Lee, Yeong Yeh, Hlebowicz, Maria, Berak, Hanna, Gasiorowski, Jacek, Halota, Waldemar, Janczewska, Ewa, Geyvandova, Natalia, Morozov, Viacheslav, Andreeva, Alla, Gusev, Denis, Bessonova, Elena, Osipenko, Marina, Romanova, Svetlana, Gankina, Natalia, Sagalova, Olga, Stepanova, Tatiana, Crespo Garcia, Javier, Diago, Moises, Inmaculada, Fernandez, Calleja, Jose Luis, Forns, Xavier, Buti, Maria, Tangkijvanich, Pisit, Tanwandee, Tawesak, Piratvisuth, Teerha, Leerapun, Apinya, Yilmaz, Gurdal, Tabak, Ömer Fehmi, Akarca, Ulus Salih, Akova, Murat, Idilman, Ramazan, Forton, Daniel, Bell, David, Agarwal, Kosh, Kennedy, Patrick, Felizarta, Franco, Sulkowski, Mark, Nahass, Ronald, Rojter, Sergio, Jacobson, Ira, Korenblat, Kevin, Gitlin, Norman, Yuen, Man-Fung, Jacobson, Ira M, Janssen, Harry L A, Kakuda, Thomas N, Lambrecht, Tom, Beumont, Maria, Kalmeijer, Ronald, Guinard-Azadian, Carine, Mayer, Cristiana, Jezorwski, John, Verbinnen, Thierry, Lenz, Oliver, Shukla, Umesh, and Biermer, Michael
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- 2023
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16. VACCELERATE Site Network: Real-time definition of clinical study capacity in Europe
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Salmanton-García, Jon, Wipfler, Pauline, Valle-Simón, Paula, Merakou, Christina, Kopsidas, Ioannis, Bethe, Ullrich, Steinbach, Angela, Spivak, Orly, Součková, Lenka, Mendonça, Maria Amélia, Koniordou, Markela, Hellemans, Margot, Frías-Iniesta, Jesus, Davis, Ruth Joanna, Barta, Imre, Azzini, Anna Maria, Askling, Helena H., Argyropoulos, Christos D., Álvarez-Barco, Elena, Akova, Murat, Bonten, Marc M.J., Cohen-Kandli, Miriam, Cox, Rebecca Jane, Flisiak, Robert, Husa, Petr, Jancoriene, Ligita, Koscalova, Alena, Launay, Odile, Lundgren, Jens, Mallon, Patrick, Marques, Laura, Nauclér, Pontus, Ochando, Jordi, Pana, Zoi-Dorothea, Tacconelli, Evelina, Tóth, Krisztina, Trelle, Sven, van Damme, Pierre, Zaoutis, Theoklis E., Zeitlinger, Markus, Albus, Kerstin, Stewart, Fiona A., Hofstraat, Sanne H.I., Bruijning-Verhagen, Patricia, and Cornely, Oliver A.
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- 2023
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17. Guideline adherence and survival of patients with candidaemia in Europe: results from the ECMM Candida III multinational European observational cohort study
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Tumbarello, Mario, Talento, Alida Fe, Ruiz, Alba C, Racil, Zdenek, Stoma, Igor, Calbacho, Maria, Van Wijngaerden, Eric, Henriques, Júlia, Jordan, Harriett, Ferroni, Valentina, Ozyurt, Ozlem Koyuncu, Milacek, Christopher, Krause, Robert, Zurl, Christoph, Backx, Matthijs, Li, Ang, Seufert, Raphael, Tomazin, Rok, Blankenheim, Yael, Dávila-Valls, Julio, García-Clemente, Paloma, Freiberger, Tomas, Buil, Jochem, Meis, Jacques F, Akyol, Deniz, Guegan, Hélène, Logan, Clare, Hoenigl, Martin, Salmanton-García, Jon, Egger, Matthias, Gangneux, Jean-Pierre, Bicanic, Tihana, Arikan-Akdagli, Sevtap, Alastruey-Izquierdo, Ana, Klimko, Nikolai, Barac, Aleksandra, Özenci, Volkan, Meijer, Eelco F J, Khanna, Nina, Bassetti, Matteo, Rautemaa-Richardson, Riina, Lagrou, Katrien, Adam, Kai-Manuel, Akalin, Emin Halis, Akova, Murat, Arsic Arsenijevic, Valentina, Aujayeb, Avinash, Blennow, Ola, Bretagne, Stéphane, Danion, François, Denis, Blandine, de Jonge, Nick Alexander, Desoubeaux, Guillaume, Drgona, Lubos, Erben, Nurettin, Gori, Andrea, García Rodríguez, Julio, Garcia-Vidal, Carolina, Giacobbe, Daniele Roberto, Goodman, Anna L, Hamal, Petr, Hammarström, Helena, Toscano, Cristina, Lanternier, Fanny, Lass-Flörl, Cornelia, Lockhart, Deborah E A, Longval, Thomas, Loughlin, Laura, Matos, Tadeja, Mikulska, Malgorzata, Narayanan, Manjusha, Martín-Pérez, Sonia, Prattes, Juergen, Rogers, Benedict, Rahimli, Laman, Ruiz, Maite, Roilides, Emmanuel, Samarkos, Michael, Scharmann, Ulrike, Sili, Uluhan, Sipahi, Oguz Resat, Sivakova, Alena, Steinmann, Joerg, Trauth, Janina, Turhan, Ozge, Van Praet, Jens, Vena, Antonio, White, P Lewis, Willinger, Birgit, Tortorano, Anna Maria, Arendrup, Maiken C, Koehler, Philipp, and Cornely, Oliver A
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- 2023
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18. Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium
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Cornely, Oliver A, Alastruey-Izquierdo, Ana, Arenz, Dorothee, Chen, Sharon CA, Dannaoui, Eric, Hochhegger, Bruno, Hoenigl, Martin, Jensen, Henrik E, Lagrou, Katrien, Lewis, Russell E, Mellinghoff, Sibylle C, Mer, Mervyn, Pana, Zoi D, Seidel, Danila, Sheppard, Donald C, Wahba, Roger, Akova, Murat, Alanio, Alexandre, Al-Hatmi, Abdullah MS, Arikan-Akdagli, Sevtap, Badali, Hamid, Ben-Ami, Ronen, Bonifaz, Alexandro, Bretagne, Stéphane, Castagnola, Elio, Chayakulkeeree, Methee, Colombo, Arnaldo L, Corzo-León, Dora E, Drgona, Lubos, Groll, Andreas H, Guinea, Jesus, Heussel, Claus-Peter, Ibrahim, Ashraf S, Kanj, Souha S, Klimko, Nikolay, Lackner, Michaela, Lamoth, Frederic, Lanternier, Fanny, Lass-Floerl, Cornelia, Lee, Dong-Gun, Lehrnbecher, Thomas, Lmimouni, Badre E, Mares, Mihai, Maschmeyer, Georg, Meis, Jacques F, Meletiadis, Joseph, Morrissey, C Orla, Nucci, Marcio, Oladele, Rita, Pagano, Livio, Pasqualotto, Alessandro, Patel, Atul, Racil, Zdenek, Richardson, Malcolm, Roilides, Emmanuel, Ruhnke, Markus, Seyedmousavi, Seyedmojtaba, Sidharthan, Neeraj, Singh, Nina, Sinko, János, Skiada, Anna, Slavin, Monica, Soman, Rajeev, Spellberg, Brad, Steinbach, William, Tan, Ban Hock, Ullmann, Andrew J, Vehreschild, Jörg J, Vehreschild, Maria JGT, Walsh, Thomas J, White, P Lewis, Wiederhold, Nathan P, Zaoutis, Theoklis, Chakrabarti, Arunaloke, and Group, Mucormycosis ECMM MSG Global Guideline Writing
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Clinical Research ,Good Health and Well Being ,Disease Management ,Humans ,Mucormycosis ,Mucormycosis ECMM MSG Global Guideline Writing Group ,Clinical Sciences ,Medical Microbiology ,Public Health and Health Services ,Microbiology - Abstract
Mucormycosis is a difficult to diagnose rare disease with high morbidity and mortality. Diagnosis is often delayed, and disease tends to progress rapidly. Urgent surgical and medical intervention is lifesaving. Guidance on the complex multidisciplinary management has potential to improve prognosis, but approaches differ between health-care settings. From January, 2018, authors from 33 countries in all United Nations regions analysed the published evidence on mucormycosis management and provided consensus recommendations addressing differences between the regions of the world as part of the "One World One Guideline" initiative of the European Confederation of Medical Mycology (ECMM). Diagnostic management does not differ greatly between world regions. Upon suspicion of mucormycosis appropriate imaging is strongly recommended to document extent of disease and is followed by strongly recommended surgical intervention. First-line treatment with high-dose liposomal amphotericin B is strongly recommended, while intravenous isavuconazole and intravenous or delayed release tablet posaconazole are recommended with moderate strength. Both triazoles are strongly recommended salvage treatments. Amphotericin B deoxycholate is recommended against, because of substantial toxicity, but may be the only option in resource limited settings. Management of mucormycosis depends on recognising disease patterns and on early diagnosis. Limited availability of contemporary treatments burdens patients in low and middle income settings. Areas of uncertainty were identified and future research directions specified.
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- 2019
19. Risk factors for infections caused by carbapenem-resistant Enterobacterales: an international matched case-control-control study (EURECA)
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de la Serna, Almudena, Monteau, Sophie, Palomo, Virginia, Soriano, Elena, Gutierrez, David, Moreno, Elisa, Palacios, Zaira, Morales, Isabel, Maldonado, Natalia, Ciezar, Antonio Plata, Ruiz Mesa, Juan Diego, Diaz, Beatriz Sobrino, Gomez, Ignacio Marquez, Camacho, Ines Perez, Frutos-Adame, Azahara, Guzman-Puche, Julia, Gracia-Ahufinger, Irene, Perez-Nadales, Elena, Torre-Gimenez, Julian, Pyrpasopoulou, Athina, Iosifidis, Elias, Chorafa, Elsa, Radovanovic, Ivana, Petrovic, Sladjana, Cvetkovi, Slavica, Melentijevic, Srdjan-Sanja, Bicmen, Can, Senol, Gunes, Tubau, Fe, Camara, Jordi, Gumucio, Victor Daniel, Bassoulis, Dimitris, Deliolanis, John, Pitiriga, Vassiliki Ch., Triarides, Nikolaos, Argiti, Efstathia, Legakis, Nikolaos J., Margarita, Kyriakidou, Gijón-Cordero, Desirée, Ruiz-Garbajosa, Patricia, Bartoloni, Alessandro, Rossolini, Gian Maria, Florescu, Simin-Aysel, Nica, Maria, Benea, Serban, Talapan, Daniela, Medić, Deana, Prijić, Sanja Maričić, Caballero, Mireia Cantero, Parra Ramírez, Lina M., Korten, Volkan, Bilgin, Hüseyin, Dalekos, George N., Stefos, Aggelos, Spyridis, Nikolaos, Michos, Athanasios, De Rosa, Francesco Giuseppe, Cavallo, Rossana, Petrosillo, Nicola, Dicaro, Antonio, Landini, Maria Paola, Ciofi degli Atti, Marta Luisa, Masanovic, Mileva, Matkovic, Dusan, Tsiodras, Sotirios, Blasi, Francesco, Di pasquale, Marta, Viscoli, Claudio, Vata, Andrei, Dorneanu, Olivia, Kapisyzi, Perlat, Vince, Adriana, Tsigou, Evdoxia, Maltezos, Efstratios, Komnos, Apostolos, Gogos, Charalampos, Franzetti, Fabio, Antonelli, Massimo, Lupse, Mihaela, Corneci, Dan, Tomescu, Dana, Georgescu, Anca, Bukarica, Ljiljana, Mitrović, Goran, Krstić, Nataša Lukić, Kurti, Arsim, Díaz-Pollán, Beatriz, Sabater, Julia Origüen, Muñoz, Patricia, Azap, Alpay, Sancak, Banu, Sahin, Arife, Akalin, Halis, Pérez-Galera, Salvador, Bravo-Ferrer, Jose M., Paniagua, María, Kostyanev, Tomislav, de Kraker, Marlieke E.A., Feifel, Jan, Sojo-Dorado, Jesús, Schotsman, Joost, Cantón, Rafael, Daikos, George L., Carevic, Biljana, Dragovac, Gorana, Tan, Lionel K., Raka, Lul, Hristea, Adriana, Viale, Pierluigi, Akova, Murat, Reguera, Jose María, Valiente de Santis, Lucía, Torre-Cisneros, Julián, Cano, Ángela, Roilides, Emmanuel, Radulovic, Lili, Kirakli, Cenk, Shaw, Evelyn, Falagas, Matthew E., Pintado, Vicente, Goossens, Herman, Bonten, Marc J., Gutiérrez-Gutiérrez, Belén, and Rodriguez-Baño, Jesús
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- 2023
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20. Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 trial
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Akova, Murat, AlAgha, Rawan, Alangaden, George, Albrecht, Svenja J, Alexander, Barbara, Al-Obaidi, Mohanad, Ambasch, German, Armestar Rodriguez, Fernando, Azap, Alpay, Baffoe-Bonnie, Anthony, Belkhir, Leila, Ben-Ami, Ronen, Boutoille, David, Cascio, Antonio, Chai, Louis YA, Chaiwarith, Romanee, Chayakulkeeree, Methee, Chen, Sharon, Chen, Yee-Chun, Chen, Yen-Hsu, Choi, Jun Yong, Choi, Young Hwa, Chotiprasitsakul, Darunee, Chung, Jin Won, Danion, François, Denis, Blandine, Diaz Santos, Emilio, Dictar, Miguel O, Diltoer, Marc, Dupont, Herve, Feng, Sizhou, Ferre Colomer, Maria Angeles, Ferrer, Ricard, Forel, Jean-Marie Fernand Roger, Fortún-Abete, Jesús, Garcia-Diaz, Julia, Girardis, Massimo, He, Fang, Hites, Maya, Ho, Mao-Wang, Honore, Patrick, Horcajada Gallego, Juan Pablo, Huang, Haihui, Huang, Po-Yen, Huang, Yong, Hussein, Osamah, Intalapaporn, Poj, Jaruratanasirikul, Sutep, Jauregui-Peredo, Luis, Johnson, Misty, Jung, Dong Sik, Jutivorakool, Kamonwan, Kern, Winfried V, Kett, Daniel H, Khawcharoenporn, Thana, Kim, Young Keun, Koehler, Philipp, Kotanidou, Anastasia, Lachiewicz, Anne, Lin, Qinhan, Lopez Cortes, Luis Eduardo, Luo, Hong, Luzzati, Roberto, Maor, Yasmin, McCarty, Todd, Merelli, Maria, Merino Amador, Paloma, Midturi, John, Migliorino, Guglielmo Marco, Mira, Jean-Paul, Mootsikapun, Piroon, Morrissey, Orla, Munoz Garcia de Paredes, Patricia, Mussini, Cristina, Mylonakis, Eleftherios, Nseir, Saadalla, Nseir, William, Odabasi, Zekaver, Papastamopoulos, Vasileios, Paterson, David, Patterson, Thomas F, Peck, Kyong Ran, Peng, Zhiyong, Permpalung, Nitipong, Plantefeve, Gaetan J, Poromanski, Ivan G, Powell, Debra, Psichogiou, Mina, Puah, Ser Hon, Pullman, John, Rahav, Galia, Martinez, Antonio Ramos, Ramos Ramos, Juan Carlos, Raz-Pasteur, Ayelet, Restrepo Castro, Carlos A, Riera, Fernando, Roblot, France, Rodriguez Alvarez, Regino Jose, Rogers, Benjamin, Roilides, Emmanuel, Sanchez Vallejo, Gregorio, Sganga, Gabriele, Sipsas, Nikolaos, Slavin, Monica, Soriano, Alex, Spec, Andrej, Strahilevitz, Jacob, Tancheva, Dora M, Tao, Zhen, Teschner, Daniel, Thompson, George R, Van Wijngaerden, Eric, Vazquez, Jose, Vergidis, Paschalis, Viale, Pierluigi, Wang, Fu-Der, Wang, Shifu, Weber, Gabriel, Weng, Jianyu, Xu, Jinfu, Yao, Li, Yavuz, Serap, Yilmaz, Mesut, Young, Jo-Anne, Zarate, Abel H, Zeng, Jun, Zhang, Yong, Thompson, George R, III, Cornely, Oliver A, Kullberg, Bart Jan, Kollef, Marin, Honore, Patrick M, Bassetti, Matteo, Poromanski, Ivan, Dignani, Cecilia, Das, Anita F, Sandison, Taylor, and Pappas, Peter G
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- 2023
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21. Immunogenicity and reactogenicity of a first booster with BNT162b2 or full-dose mRNA-1273: A randomised VACCELERATE trial in adults ≥75 years (EU-COVAT-1)
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Neuhann, Julia M., Stemler, Jannik, Carcas, Antonio J., Frías-Iniesta, Jesús, Akova, Murat, Bethe, Ullrich, Heringer, Sarah, Salmanton-García, Jon, Tischmann, Lea, Zarrouk, Marouan, Cüppers, Arnd, Grothe, Jan, Leon, Alejandro Garcia, Mallon, Patrick, Negi, Riya, Gaillard, Colette, Saini, Gurvin, Lammens, Christine, Hotterbeekx, An, Loens, Katherine, Malhotra-Kumar, Surbhi, Goossens, Herman, Kumar-Singh, Samir, König, Franz, Yeghiazaryan, Lusine, Posch, Martin, Koehler, Philipp, and Cornely, Oliver A.
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- 2023
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22. Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study
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Niccolò Buetti, Alexis Tabah, Ambre Loiodice, Stéphane Ruckly, Abdullah Tarik Aslan, Giorgia Montrucchio, Andrea Cortegiani, Nese Saltoglu, Bircan Kayaaslan, Firdevs Aksoy, Akova Murat, Özlem Akdoğan, Kemal Tolga Saracoglu, Cem Erdogan, Marc Leone, Ricard Ferrer, José-Artur Paiva, Yoshiro Hayashi, Mahesh Ramanan, Andrew Conway Morris, François Barbier, Jean-François Timsit, and the Eurobact 2 study group
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Bloodstream infection ,ICU-acquired ,COVID-19 ,Enterococcus ,Bacteremia ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Abstract Background The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 and non-COVID-19 critically ill patients. Methods We used data from the Eurobact II study, a prospective observational multicontinental cohort study on HABSI treated in ICU. For the current analysis, we selected centers that included both COVID-19 and non-COVID-19 critically ill patients. We performed descriptive statistics between COVID-19 and non-COVID-19 in terms of patients’ characteristics, source of infection and microorganism distribution. We studied the association between COVID-19 status and mortality using multivariable fragility Cox models. Results A total of 53 centers from 19 countries over the 5 continents were eligible. Overall, 829 patients (median age 65 years [IQR 55; 74]; male, n = 538 [64.9%]) were treated for a HABSI. Included patients comprised 252 (30.4%) COVID-19 and 577 (69.6%) non-COVID-19 patients. The time interval between hospital admission and HABSI was similar between both groups. Respiratory sources (40.1 vs. 26.0%, p
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- 2022
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23. Mycobacterial infections in adults with haematological malignancies and haematopoietic stem cell transplants: guidelines from the 8th European Conference on Infections in Leukaemia
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Greinix, Hildegard, Maertens, Johan, De Greef, Julien, Slavin, Monica, Spriet, Isabel, Hubacek, Petr, Bergeron, Anne, Cordonnier, Catherine, Kanerva, Jukka, Herbrecht, Raoul, Herrmann, Jean-Louis, Lanternier, Fanny, Bondeelle, Louise, Robin, Christine, Einsele, Hermann, Lehrnbecher, Thomas, Groll, Andreas, Maschmeyer, Georg, Lange, Christoph, von Lilienfeld-Toal, Marie, Pana, Dorothea, Roilides, Emmanuel, Kassa, Csaba, Averbuch, Diana, Engelhard, Dan, Cesaro, Simone, Mikulska, Malgorzata, Pagano, Livio, Castagnola, Elio, Compagno, Francesca, Goletti, Delia, Mesini, Alessio, Donnelly, Peter J, Styczynski, Jan, Botelho de Sousa, Aida, Aljurf, Mahmoud, de la Camara, Rafael, Navarro, David, Rovira, Montserrat, Franquet, Tomas, Garcia-Vidal, Carol, Ljungman, Per, Paukssen, Karlis, Ammann, Roland, Lamoth, Frédéric, Hirsch, Hans, Ritz, Nicole, Akova, Murat, Ceesay, Mansour, Warris, Adilia, Chemaly, Roy, and Donnelly, J Peter
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- 2022
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24. Comparison of ceftazidime-avibactam susceptibility testing methods against OXA-48-like carrying Klebsiella blood stream isolates
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Isler, Burcu, Vatansever, Cansel, Özer, Berna, Çınar, Güle, Aslan, Abdullah Tarık, Stewart, Adam, Simos, Peter, Falconer, Caitlin, Bauer, Michelle J., Forde, Brian, Harris, Patrick, Şimşek, Funda, Tülek, Necla, Demirkaya, Hamiyet, Menekşe, Şirin, Akalin, Halis, Balkan, İlker İnanç, Aydın, Mehtap, Tigen, Elif Tükenmez, Demir, Safiye Koçulu, Kapmaz, Mahir, Keske, Şiran, Doğan, Özlem, Arabacı, Çiğdem, Yağcı, Serap, Hazırolan, Gülşen, Bakır, Veli Oğuzalp, Gönen, Mehmet, Saltoğlu, Neşe, Azap, Alpay, Azap, Özlem, Akova, Murat, Ergönül, Önder, Paterson, David L., and Can, Füsun
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- 2022
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25. Characteristics and outcomes of carbapenemase harbouring carbapenem-resistant Klebsiella spp. bloodstream infections: a multicentre prospective cohort study in an OXA-48 endemic setting
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Isler, Burcu, Özer, Berna, Çınar, Güle, Aslan, Abdullah Tarık, Vatansever, Cansel, Falconer, Caitlin, Dolapçı, İştar, Şimşek, Funda, Tülek, Necla, Demirkaya, Hamiyet, Menekşe, Şirin, Akalin, Halis, Balkan, İlker İnanç, Aydın, Mehtap, Tigen, Elif Tükenmez, Demir, Safiye Koçulu, Kapmaz, Mahir, Keske, Şiran, Doğan, Özlem, Arabacı, Çiğdem, Yağcı, Serap, Hazırolan, Gülşen, Bakır, Veli Oğuzalp, Gönen, Mehmet, Chatfield, Mark D., Forde, Brian, Saltoğlu, Neşe, Azap, Alpay, Azap, Özlem, Akova, Murat, Paterson, David L., Can, Füsun, and Ergönül, Önder
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- 2022
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26. European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine)
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Paul, Mical, Carrara, Elena, Retamar, Pilar, Tängdén, Thomas, Bitterman, Roni, Bonomo, Robert A., de Waele, Jan, Daikos, George L., Akova, Murat, Harbarth, Stephan, Pulcini, Celine, Garnacho-Montero, José, Seme, Katja, Tumbarello, Mario, Lindemann, Paul Christoffer, Gandra, Sumanth, Yu, Yunsong, Bassetti, Matteo, Mouton, Johan W., Tacconelli, Evelina, and Rodríguez-Baño, Jesús
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- 2022
- Full Text
- View/download PDF
27. Predictive modeling of mortality in carbapenem-resistant Acinetobacter baumannii bloodstream infections using machine learning.
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Özdede, Murat, Zarakolu, Pınar, Metan, Gökhan, Eser, Özgen Köseoğlu, Selimova, Cemile, Kızılkaya, Canan, Elmalı, Ferhan, and Akova, Murat
- Abstract
Acinetobacter baumannii, a notable drug-resistant bacterium, often induces severe infections in healthcare settings, prompting a deeper exploration of treatment alternatives due to escalating carbapenem resistance. This study meticulously examined clinical, microbiological, and molecular aspects related to in-hospital mortality in patients with carbapenem-resistant A. baumannii (CRAB) bloodstream infections (BSIs). From 292 isolates, 153 cases were scrutinized, reidentified through matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), and evaluated for antimicrobial susceptibility and carbapenemase genes via multiplex polymerase chain reaction (PCR). Utilizing supervised machine learning, the study constructed models to predict 14- and 30-day mortality rates, revealing the Naïve Bayes model's superior specificity (0.75) and area under the curve (0.822) for 14-day mortality, and the Random Forest model's impressive recall (0.85) for 30-day mortality. These models delineated eight and nine significant features for 14- and 30-day mortality predictions, respectively, with "septic shock" as a pivotal variable. Additional variables such as neutropenia with neutropenic days prior to sepsis, mechanical ventilator support, chronic kidney disease, and heart failure were also identified as ranking features. However, empirical antibiotic therapy appropriateness and specific microbiological data had minimal predictive efficacy. This research offers foundational data for assessing mortality risks associated with CRAB BSI and underscores the importance of stringent infection control practices in the wake of the scarcity of new effective antibiotics against resistant strains. The advanced models and insights generated in this study serve as significant resources for managing the repercussions of A. baumannii infections, contributing substantially to the clinical understanding and management of such infections in healthcare environments. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
28. An Institutional Febrile Neutropenia Protocol Improved the Antibacterial Treatment and Encouraged the Development of a Computerized Clinical Decision Support System.
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Taş, Zahit, Metan, Gökhan, Telli Dizman, Gülçin, Yavuz, Eren, Dizdar, Ömer, Büyükaşık, Yahya, Uzun, Ömrüm, and Akova, Murat
- Subjects
CLINICAL decision support systems ,HEMATOPOIETIC stem cell transplantation ,FEBRILE neutropenia ,DECISION support systems ,HEMATOLOGIC malignancies - Abstract
We investigated the influence of a local guideline on the quality of febrile neutropenia (FN) management and the applicability of a computerized decision support system (CDSS) using real-life data. The study included 227 FN patients between April 2016 and January 2019. The primary outcome measure was the achievement of a 20% increase in the rate of appropriate empirical treatment of FN in bacteremic patients. The compatibility of the CDSS (the development of which was completed in November 2021) with local protocols was tested using standard patient scenarios and empirical antibiotic recommendations for bacteremic FN patients. In total, 91 patients were evaluated before (P1: between April 2016 and May 2017) and 136 after (P2: between May 2017 and January 2019) the guideline's release (May 2017). The demographic characteristics were similar. Appropriate empirical antibacterial treatment was achieved in 58.3% of P1 and 88.1% of P2 patients (p = 0.006). The need for escalation of antibacterial treatment was significantly lower in P2 (49.5% vs. 35.3%; p = 0.03). In P2, the performance of the CDSS and consulting physicians was similar (CDSS 88.8% vs. physician 88.83%; p = 1) regarding appropriate empirical antibacterial treatment. The introduction of the local guideline improved the appropriateness of initial empirical treatment and reduced escalation rates in FN patients. The high rate of compliance of the CDSS with the local guideline-based decisions in P2 highlights the usefulness of the CDSS for these patients. [ABSTRACT FROM AUTHOR]
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- 2024
- Full Text
- View/download PDF
29. Risk factors for bloodstream infections due to carbapenem-resistant Enterobacterales: a nested case-control-control study.
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Zhou, Hongyu, Buetti, Niccolò, Pérez-Galera, Salvador, Bravo-Ferrer, Jose, Gutiérrez-Gutiérrez, Belén, Paniagua-García, María, Feifel, Jan, Sauser, Julien, Kostyanev, Tomi, Canton, Rafael, Tan, Lionel K, Basoulis, Dimitris, Pintado, Vicente, Roilides, Emmanuel, Dragovac, Gorana, Torre-Cisneros, Julian, Mediç, Deana, Akova, Murat, Goossens, Herman, and Bonten, Marc
- Subjects
INFECTION prevention ,COLONIZATION (Ecology) ,MEDICAL referrals ,ANTIMICROBIAL stewardship ,LONG-term health care ,LONG-term care facilities - Abstract
Background Carbapenem-resistant Enterobacterales (CRE) bloodstream infections (BSIs) are a major threat to patients. To date, data on risk factors have been limited, with low internal and external validity. In this multicentre study, risk factors for CRE BSI were determined by comparison with two control groups: patients with carbapenem-susceptible Enterobacterales (CSE) BSI, and patients without Enterobacterales infection (uninfected patients). Methods A multicentre, case-control-control study was nested in a European prospective cohort study on CRE (EURECA). CRE BSI:CSE BSI matching was 1:1, CRE BSI:Uninfected patients matching was 1:3, based on hospital, ward and length of stay. Conditional logistic regression was applied. Results From March 2016 to November 2018, 73 CRE BSIs, 73 CSE BSIs and 219 uninfected patients were included from 18 European hospitals. For CRE versus CSE BSI, previous CRE colonization/infection [incidence rate ratio (IRR) 7.32; 95% CI 1.65–32.38) increased the risk. For CRE versus uninfected controls, independent risk factors included: older age (IRR 1.03; 95% CI 1.01–1.06), patient referral (long-term care facility: IRR 7.19; 95% CI 1.51–34.24; acute care hospital: IRR 5.26; 95% CI 1.61–17.11), previous colonization/infection with other MDR organisms (MDROs) (IRR 9.71; 95% CI 2.33–40.56), haemodialysis (IRR 8.59; 95% CI 1.82–40.53), invasive procedures (IRR 5.66; 95% CI 2.11–15.16), and β-lactam/β-lactamase inhibitor combinations (IRR 3.92; 95% CI 1.68–9.13) or third/fourth generation cephalosporin (IRR 2.75; 95% CI 1.06–7.11) exposure within 3 months before enrolment. Conclusions Evidence of previous CRE colonization/infection was a major risk factor for carbapenem resistance among Enterobacterales BSI. Compared with uninfected patients, evidence of previous MDRO colonization/infection and healthcare exposure were important risk factors for CRE BSI. Targeted screening, infection prevention and antimicrobial stewardship should focus on these high-risk patients. [ABSTRACT FROM AUTHOR]
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- 2024
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30. Gram-Negative Infections
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Bassetti, Matteo, Righi, Elda, Akova, Murat, Dreyling, Martin, Series Editor, Cornely, Oliver A., editor, and Hoenigl, Martin, editor
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- 2021
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31. Do antimicrobial stewardship programs improve the quality of care in ICU patients diagnosed with infectious diseases following consultation? Experience in a tertiary care hospital
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GURSOY, Gamze, UZUN, Omrum, METAN, Gokhan, YILDIRIM, Mehmet, BAHAP, Melda, DEMIRKAN, Salih Kutay, TOPELI, Arzu, AKINCI, Seda Banu, TOPCUOGLU, Mehmet Akif, BERKER, Mustafa, HAZIROLAN, Gulsen, AKOVA, Murat, and UNAL, Serhat
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- 2022
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32. Pseudomonas aeruginosa Bloodstream Infections Presenting with Septic Shock in Neutropenic Cancer Patients: Impact of Empirical Antibiotic Therapy
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Royo-Cebrecos, Cristina, primary, Laporte-Amargós, Júlia, additional, Peña, Marta, additional, Ruiz-Camps, Isabel, additional, Garcia-Vidal, Carolina, additional, Abdala, Edson, additional, Oltolini, Chiara, additional, Akova, Murat, additional, Montejo, Miguel, additional, Mikulska, Malgorzata, additional, Martín-Dávila, Pilar, additional, Herrera, Fabián, additional, Gasch, Oriol, additional, Drgona, Lubos, additional, Morales, Hugo Manuel Paz, additional, Brunel, Anne-Sophie, additional, García, Estefanía, additional, Isler, Burcu, additional, Kern, Winfried V., additional, Palacios-Baena, Zaira R., additional, de la Calle, Guillermo Maestr, additional, Montero, Maria Milagro, additional, Kanj, Souha S., additional, Sipahi, Oguz R., additional, Calik, Sebnem, additional, Márquez-Gómez, Ignacio, additional, Marin, Jorge I., additional, Gomes, Marisa Z. R., additional, Hemmatii, Philipp, additional, Araos, Rafael, additional, Peghin, Maddalena, additional, Del Pozo, Jose L., additional, Yáñez, Lucrecia, additional, Tilley, Robert, additional, Manzur, Adriana, additional, Novo, Andrés, additional, Carratalà, Jordi, additional, and Gudiol, Carlota, additional
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- 2024
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33. Dirençli Gram-Negatif Bakteri İnfeksiyonlarının Yönetiminde Sık Karşılaşılan Sorunlar ve Çözüm Önerileri: Klinik Pratiğe Yönelik Uzman Görüş
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SÜMER, Şua, primary, KURT AZAP, Özlem, additional, AYGÜN, Gökhan, additional, AKALIN, Halis, additional, AKOVA, Murat, additional, and KÖKSAL, İftihar, additional
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- 2024
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34. Comparison of teicoplanin versus vancomycin in combination with piperacillin-tazobactam or meropenem for the risk of acute kidney injury
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Aslan, Abdullah Tarık, Pashayev, Tural, Dağ, Osman, and Akova, Murat
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- 2021
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35. Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey
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Kayaaslan, Bircan, Hasanoğlu, İmran, Dalkıran, Ayça, Aydos, Ömer, Çınar, Güle, Akdemir-Kalkan, İrem, İnkaya, Ahmet Çağkan, Aydin, Mehtap, Çakir, Hatice, Yıldız, Jale, Kocabıyık, Özenir, Arslan, Sonay, Nallı, Bayram, Demir, Ömer, Singil, Sarp, Ataman-Hatipoğlu, Çiğdem, Tuncer-Ertem, Günay, Kınıklı, Sami, Önal, Uğur, Mete, Bilgül, Dalgan, Gözde, Taşbakan, Meltem, Yamazhan, Tansu, Kömürcüoğlu, Berna, Yalnız, Enver, Benli, Aysun, Keskin-Sarıtaş, Çağla, Ertosun, Mustafa Gökhan, Özkan, Özlenen, Emre, Salih, Arıca, Seçil, Kuşçu, Ferit, Candevir, Aslıhan, Ertürk-Şengel, Buket, Ayvaz, Fadime, Aksoy, Firdevs, Mermutluoğlu, Çiğdem, Demir, Yakup, Günlüoğlu, Gülşah, Tural-Önür, Seda, Kılıç-Toker, Ayşin, Eren, Esma, Otlu, Barış, Mete, Ayşe Özlem, Koçak, Kübra, Ateş, Hale, Koca-Kalkan, İlkay, Aksu, Kurtuluş, Tanriover, Mine Durusu, Doğanay, Hamdi Levent, Akova, Murat, Güner, Hatice Rahmet, Azap, Alpay, Akhan, Sıla, Köse, Şükran, Erdinç, Fatma Şebnem, Akalın, Emin Halis, Tabak, Ömer Fehmi, Pullukçu, Hüsnü, Batum, Özgür, Şimşek Yavuz, Serap, Turhan, Özge, Yıldırmak, Mustafa Taner, Köksal, İftihar, Taşova, Yeşim, Korten, Volkan, Yılmaz, Gürdal, Çelen, Mustafa Kemal, Altın, Sedat, Çelik, İlhami, Bayındır, Yaşar, Karaoğlan, İlkay, Yılmaz, Aydın, Özkul, Aykut, Gür, Hazal, and Unal, Serhat
- Published
- 2021
- Full Text
- View/download PDF
36. Predictive modeling of mortality in carbapenem-resistant Acinetobacter baumanniibloodstream infections using machine learning
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Özdede, Murat, Zarakolu, Pınar, Metan, Gökhan, Köseoğlu Eser, Özgen, Selimova, Cemile, Kızılkaya, Canan, Elmalı, Ferhan, and Akova, Murat
- Abstract
Acinetobacter baumannii, a notable drug-resistant bacterium, often induces severe infections in healthcare settings, prompting a deeper exploration of treatment alternatives due to escalating carbapenem resistance. This study meticulously examined clinical, microbiological, and molecular aspects related to in-hospital mortality in patients with carbapenem-resistant A. baumannii(CRAB) bloodstream infections (BSIs). From 292 isolates, 153 cases were scrutinized, reidentified through matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), and evaluated for antimicrobial susceptibility and carbapenemase genes via multiplex polymerase chain reaction (PCR). Utilizing supervised machine learning, the study constructed models to predict 14- and 30-day mortality rates, revealing the Naïve Bayes model’s superior specificity (0.75) and area under the curve (0.822) for 14-day mortality, and the Random Forest model’s impressive recall (0.85) for 30-day mortality. These models delineated eight and nine significant features for 14- and 30-day mortality predictions, respectively, with “septic shock” as a pivotal variable. Additional variables such as neutropenia with neutropenic days prior to sepsis, mechanical ventilator support, chronic kidney disease, and heart failure were also identified as ranking features. However, empirical antibiotic therapy appropriateness and specific microbiological data had minimal predictive efficacy. This research offers foundational data for assessing mortality risks associated with CRAB BSI and underscores the importance of stringent infection control practices in the wake of the scarcity of new effective antibiotics against resistant strains. The advanced models and insights generated in this study serve as significant resources for managing the repercussions of A. baumanniiinfections, contributing substantially to the clinical understanding and management of such infections in healthcare environments.
- Published
- 2024
- Full Text
- View/download PDF
37. Expect the unexpected: fungemia caused by uncommon Candida species in a Turkish University Hospital
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Alp, Sehnaz, Gulmez, Dolunay, Kardas, Rıza Can, Karahan, Gizem, Tas, Zahit, Gursoy, Gamze, Ayaz-Ceylan, Caglayan Merve, Arikan-Akdagli, Sevtap, and Akova, Murat
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- 2021
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38. Attributable mortality of infections caused by carbapenem-resistant Enterobacterales: results from a prospective, multinational case-control-control matched cohorts study (EURECA)
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Julius Centrum, Ecraid, Epi Infectieziekten, Infection & Immunity, Epidemiology of Sepsis & Inflammation in Critically Ill Patients, JC onderzoeksprogramma Infectious Diseases, Paniagua-García, María, Bravo-Ferrer, Jose M, Pérez-Galera, Salvador, Kostyanev, Tomislav, de Kraker, Marlieke E A, Feifel, Jan, Palacios-Baena, Zaira R, Schotsman, Joost, Cantón, Rafael, Daikos, George L, Carevic, Biljana, Dragovac, Gorana, Tan, Lionel K, Raka, Lul, Hristea, Adriana, Viale, Pierluigi, Akova, Murat, Cano, Ángela, Reguera, Jose María, Bartoloni, Alessandro, Florescu, Simin-Aysel, Benea, Serban, Bukarica, Ljiljana, Asensio, Ángel, Korten, Volkan, Grundmann, Hajo, Goossens, Herman, Bonten, Marc J, Gutiérrez-Gutiérrez, Belén, Rodríguez-Baño, Jesús, COMBACTE-CARE-EURECA Team, Julius Centrum, Ecraid, Epi Infectieziekten, Infection & Immunity, Epidemiology of Sepsis & Inflammation in Critically Ill Patients, JC onderzoeksprogramma Infectious Diseases, Paniagua-García, María, Bravo-Ferrer, Jose M, Pérez-Galera, Salvador, Kostyanev, Tomislav, de Kraker, Marlieke E A, Feifel, Jan, Palacios-Baena, Zaira R, Schotsman, Joost, Cantón, Rafael, Daikos, George L, Carevic, Biljana, Dragovac, Gorana, Tan, Lionel K, Raka, Lul, Hristea, Adriana, Viale, Pierluigi, Akova, Murat, Cano, Ángela, Reguera, Jose María, Bartoloni, Alessandro, Florescu, Simin-Aysel, Benea, Serban, Bukarica, Ljiljana, Asensio, Ángel, Korten, Volkan, Grundmann, Hajo, Goossens, Herman, Bonten, Marc J, Gutiérrez-Gutiérrez, Belén, Rodríguez-Baño, Jesús, and COMBACTE-CARE-EURECA Team
- Published
- 2024
39. Risk factors for bloodstream infections due to carbapenem-resistant Enterobacterales: a nested case-control-control study
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Epi Infectieziekten, Infection & Immunity, Epidemiology of Sepsis & Inflammation in Critically Ill Patients, JC onderzoeksprogramma Infectious Diseases, Zhou, Hongyu, Buetti, Niccolò, Pérez-Galera, Salvador, Bravo-Ferrer, Jose, Gutiérrez-Gutiérrez, Belén, Paniagua-García, María, Feifel, Jan, Sauser, Julien, Kostyanev, Tomi, Canton, Rafael, Tan, Lionel K, Basoulis, Dimitris, Pintado, Vicente, Roilides, Emmanuel, Dragovac, Gorana, Torre-Cisneros, Julian, Mediç, Deana, Akova, Murat, Goossens, Herman, Bonten, Marc, Harbarth, Stephan, Rodriguez-Baño, Jesus, De Kraker, Marlieke E A, COMBACTE- EURECA project team, Epi Infectieziekten, Infection & Immunity, Epidemiology of Sepsis & Inflammation in Critically Ill Patients, JC onderzoeksprogramma Infectious Diseases, Zhou, Hongyu, Buetti, Niccolò, Pérez-Galera, Salvador, Bravo-Ferrer, Jose, Gutiérrez-Gutiérrez, Belén, Paniagua-García, María, Feifel, Jan, Sauser, Julien, Kostyanev, Tomi, Canton, Rafael, Tan, Lionel K, Basoulis, Dimitris, Pintado, Vicente, Roilides, Emmanuel, Dragovac, Gorana, Torre-Cisneros, Julian, Mediç, Deana, Akova, Murat, Goossens, Herman, Bonten, Marc, Harbarth, Stephan, Rodriguez-Baño, Jesus, De Kraker, Marlieke E A, and COMBACTE- EURECA project team
- Published
- 2024
40. Vaccination in Patients with a Gastrointestinal Cancer
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Alp, Şehnaz, Akova, Murat, Yalcin, Suayib, editor, and Philip, Philip A., editor
- Published
- 2019
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41. Attributable mortality of infections caused by carbapenem-resistant Enterobacterales: results from a prospective, multinational case-control-control matched cohorts study (EURECA)
- Author
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Paniagua-García, María, primary, Bravo-Ferrer, Jose M., additional, Pérez-Galera, Salvador, additional, Kostyanev, Tomislav, additional, de Kraker, Marlieke E.A., additional, Feifel, Jan, additional, Palacios-Baena, Zaira R., additional, Schotsman, Joost, additional, Cantón, Rafael, additional, Daikos, George L., additional, Carevic, Biljana, additional, Dragovac, Gorana, additional, Tan, Lionel K., additional, Raka, Lul, additional, Hristea, Adriana, additional, Viale, Pierluigi, additional, Akova, Murat, additional, Cano, Ángela, additional, Reguera, Jose María, additional, Bartoloni, Alessandro, additional, Florescu, Simin-Aysel, additional, Benea, Serban, additional, Bukarica, Ljiljana, additional, Asensio, Ángel, additional, Korten, Volkan, additional, Grundmann, Hajo, additional, Goossens, Herman, additional, Bonten, Marc J., additional, Gutiérrez-Gutiérrez, Belén, additional, Rodríguez-Baño, Jesús, additional, Serna, Almudena de la, additional, Monteau, Sophie, additional, Palomo, Virginia, additional, Soriano, Elena, additional, Gutierrez, David, additional, Moreno, Elisa, additional, Sojo-Dorado, Jesus, additional, Morales, Isabel, additional, Maldonado, Natalia, additional, Santis, Lucia Valiente de, additional, Ciezar, Antonio Plata, additional, Ruiz Mesa, Juan Diego, additional, Diaz, Beatriz Sobrino, additional, Gomez, Ignacio Marquez, additional, Camacho, Ines Perez, additional, Cano, Angela, additional, Frutos-Adame, Azahara, additional, Guzman-Puche, Julia, additional, Gracia-Ahufinger, Irene, additional, Perez-Nadales, Elena, additional, Torre-Gimenez, Julian, additional, Pyrpasopoulou, Athina, additional, Iosifidis, Elias, additional, Chorafa, Elsa, additional, Radovanovic, Ivana, additional, Petrovic, Sladjana, additional, Cvetkovi, Slavica, additional, Melentijevic, Srdjan-Sanja, additional, Bicmen, Can, additional, Senol, Gunes, additional, Tubau, Fe, additional, Camara, Jordi, additional, Daniel Gumucio, Victor, additional, Bassoulis, Dimitris, additional, Deliolanis, John, additional, Pitiriga, Vassiliki Ch., additional, Triarides, Nikolaos, additional, Argiti, Efstathia, additional, Legakis, Nikolaos J., additional, Margarita, Kyriakidou, additional, Gijón-Cordero, Desirée, additional, Ruiz-Garbajosa, Patricia, additional, Rossolini, Gian Maria, additional, Nica, Maria, additional, Talapan, Daniela, additional, Medić, Deana, additional, Prijić, Sanja Maričić, additional, Caballero, Mireia Cantero, additional, Ramírez, Lina M Parra, additional, Bilgin, Hüseyin, additional, Dalekos, George N., additional, Stefos, Aggelos, additional, Spyridis, Nikolaos, additional, Michos, Athanasios, additional, De Rosa, Francesco Giuseppe, additional, Cavallo, Rossana, additional, Petrosillo, Nicola, additional, Dicaro, Antonio, additional, Landini, Maria Paola, additional, degli Atti, Marta Luisa Ciofi, additional, Masanovic, Mileva, additional, Matkovic, Dusan, additional, Tsiodras, Sotirios, additional, Blasi, Francesco, additional, pasquale, Marta Di, additional, Viscoli, Claudio, additional, Vata, Andrei, additional, Dorneanu, Olivia, additional, Kapisyzi, Perlat, additional, Vince, Adriana, additional, Tsigou, Evdoxia, additional, Maltezos, Efstratios, additional, Komnos, Apostolos, additional, Gogos, Charalampos, additional, Franzetti, Fabio, additional, Antonelli, Massimo, additional, Lupse, Mihaela, additional, Corneci, Dan, additional, Tomescu, Dana, additional, Georgescu, Anca, additional, Mitrović, Goran, additional, Krstić, Nataša Lukić, additional, Kurti, Arsim, additional, Reuter, Sandra, additional, Díaz-Pollán, Beatriz, additional, Sabater, Julia Origüen, additional, Muñoz, Patricia, additional, Azap, Alpay, additional, ancak, Banu, additional, Sahin, Arife, additional, and Akalin, Halis, additional
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- 2024
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42. Current Practice of Antimicrobial Prophylaxis to Prevent Gram-Negative Bacterial Infection in High-Risk Haematology Patients: Results from an International Survey
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Stemler, Jannik, primary, Gavriilaki, Eleni, additional, Hlukhareva, Oksana, additional, Khanna, Nina, additional, Akova, Murat, additional, Pagano, Livio, additional, Cisneros, José Miguel, additional, Cornely, Oliver A., additional, and Salmanton-Garcia, Jon, additional
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- 2024
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43. Lung and kidney perfusion deficits diagnosed by dual-energy computed tomography in patients with COVID-19-related systemic microangiopathy
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Idilman, Ilkay S., Telli Dizman, Gulcin, Ardali Duzgun, Selin, Irmak, Ilim, Karcaaltincaba, Musturay, Inkaya, Ahmet Cagkan, Demirkazik, Figen, Durhan, Gamze, Gulsun Akpinar, Meltem, Ariyurek, Orhan Macit, Akpinar, Erhan, Rello, Jordi, Akova, Murat, and Akata, Deniz
- Published
- 2021
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44. “Good” News from IDCM and Thanks to All Who Contributed
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Akova, Murat, primary
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- 2023
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45. A randomized, double-blind, placebo-controlled phase III clinical trial to evaluate the efficacy and safety of SARS-CoV-2 vaccine (inactivated, Vero cell): a structured summary of a study protocol for a randomised controlled trial
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Akova, Murat and Unal, Serhat
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- 2021
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46. Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study
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De Bus, Liesbet, Depuydt, Pieter, Steen, Johan, Dhaese, Sofie, De Smet, Ken, Tabah, Alexis, and Akova, Murat
- Subjects
Merck & Company Inc. ,Medical research -- Health aspects ,Medicine, Experimental -- Health aspects ,Bacterial infections -- Care and treatment ,Infection -- Care and treatment ,Methicillin -- Health aspects ,Hospital patients -- Care and treatment ,Pharmaceutical industry -- Health aspects ,Health care industry - Abstract
Purpose The DIANA study aimed to evaluate how often antimicrobial de-escalation (ADE) of empirical treatment is performed in the intensive care unit (ICU) and to estimate the effect of ADE on clinical cure on day 7 following treatment initiation. Methods Adult ICU patients receiving empirical antimicrobial therapy for bacterial infection were studied in a prospective observational study from October 2016 until May 2018. ADE was defined as (1) discontinuation of an antimicrobial in case of empirical combination therapy or (2) replacement of an antimicrobial with the intention to narrow the antimicrobial spectrum, within the first 3 days of therapy. Inverse probability (IP) weighting was used to account for time-varying confounding when estimating the effect of ADE on clinical cure. Results Overall, 1495 patients from 152 ICUs in 28 countries were studied. Combination therapy was prescribed in 50%, and carbapenems were prescribed in 26% of patients. Empirical therapy underwent ADE, no change and change other than ADE within the first 3 days in 16%, 63% and 22%, respectively. Unadjusted mortality at day 28 was 15.8% in the ADE cohort and 19.4% in patients with no change [p = 0.27; RR 0.83 (95% CI 0.60-1.14)]. The IP-weighted relative risk estimate for clinical cure comparing ADE with no-ADE patients (no change or change other than ADE) was 1.37 (95% CI 1.14-1.64). Conclusion ADE was infrequently applied in critically ill-infected patients. The observational effect estimate on clinical cure suggested no deleterious impact of ADE compared to no-ADE. However, residual confounding is likely., Author(s): Liesbet De Bus [sup.1], Pieter Depuydt [sup.1] [sup.2], Johan Steen [sup.1] [sup.3] [sup.4], Sofie Dhaese [sup.1], Ken De Smet [sup.1], Alexis Tabah [sup.5] [sup.6], Murat Akova [sup.7], Menino Osbert [...]
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- 2020
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47. The Challenges of Vaccine Trial Participation among Underserved and Hard-to-Reach Communities: An Internal Expert Consultation of the VACCELERATE Consortium
- Author
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Poulimeneas, Dimitrios, primary, Koniordou, Markela, additional, Kousi, Dimitra, additional, Merakou, Christina, additional, Kopsidas, Ioannis, additional, Tsopela, Grammatiki Christina, additional, Argyropoulos, Christos D., additional, Themistocleous, Sophia C., additional, Shiamakkides, George, additional, Constantinou, Marinos, additional, Alexandrou, Alexandra, additional, Noula, Evgenia, additional, Nearchou, Andria, additional, Salmanton-García, Jon, additional, Stewart, Fiona A., additional, Heringer, Sarah, additional, Albus, Kerstin, additional, Álvarez-Barco, Elena, additional, Macken, Alan, additional, Di Marzo, Romina, additional, Luis, Catarina, additional, Valle-Simón, Paula, additional, Askling, Helena H., additional, Hellemans, Margot, additional, Spivak, Orly, additional, Davis, Ruth Joanna, additional, Azzini, Anna Maria, additional, Barta, Imre, additional, Součková, Lenka, additional, Jancoriene, Ligita, additional, Akova, Murat, additional, Mallon, Patrick W. G., additional, Olesen, Ole F., additional, Frias-Iniesta, Jesus, additional, van Damme, Pierre, additional, Tóth, Krisztina, additional, Cohen-Kandli, Miriam, additional, Cox, Rebecca Jane, additional, Husa, Petr, additional, Nauclér, Pontus, additional, Marques, Laura, additional, Ochando, Jordi, additional, Tacconelli, Evelina, additional, Zeitlinger, Markus, additional, Cornely, Oliver A., additional, Pana, Zoi Dorothea, additional, and Zaoutis, Theoklis E., additional
- Published
- 2023
- Full Text
- View/download PDF
48. 2746. Assessment of in vitro synergy between Piperacillin-Tazobactam-Meropenem and Imipenem-Meropenem against OXA-48 Producing Klebsiella pneumoniae Using Time-Kill Assays
- Author
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Demir, Mervenur, primary, Aslan, Abdullah Tarik, additional, Seren Tanrıverdi, Elif, additional, Otlu, Barış, additional, Akova, Murat, additional, Paterson, David, additional, Harris, Patrick N A, additional, and Hazırolan, Gülşen, additional
- Published
- 2023
- Full Text
- View/download PDF
49. Consensus position statement on advancing the standardised reporting of infection events in immunocompromised patients
- Author
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Teh, Benjamin W, primary, Mikulska, Malgorzata, additional, Averbuch, Dina, additional, de la Camara, Rafael, additional, Hirsch, Hans H, additional, Akova, Murat, additional, Ostrosky-Zeichner, Luis, additional, Baddley, John W, additional, Tan, Ban Hock, additional, Mularoni, Alessandra, additional, Subramanian, Aruna K, additional, La Hoz, Ricardo M, additional, Marinelli, Tina, additional, Boan, Peter, additional, Aguado, Jose Maria, additional, Grossi, Paolo A, additional, Maertens, Johan, additional, Mueller, Nicolas J, additional, and Slavin, Monica A, additional
- Published
- 2023
- Full Text
- View/download PDF
50. Gram-Negative Infections
- Author
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Bassetti, Matteo, primary, Righi, Elda, additional, and Akova, Murat, additional
- Published
- 2020
- Full Text
- View/download PDF
Catalog
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