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2. Corrigendum to “Severe disease reactivation in seropositive neuromyelitis optica spectrum disorders patients after stopping eculizumab treatment” [Multiple Sclerosis and Related Disorders, Volume 79, November 2023, https://doi.org/10.1016/j.msard.2023.104949]

Author

Sen, Sedat, Tuncer, Asli, Terzi, Murat, Bunul, Sena Destan, Ozen-Acar, Pinar, Altunrende, Burcu, Ozakbas, Serkan, Tutuncu, Melih, Uygunoglu, Ugur, Akman-Demir, Gulsen, Karabudak, Rana, Efendi, Husnu, and Siva, Aksel

Published
2024
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3. Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

Author

Achiron, Anat, Achtnichts, Lutz, Agan, Kadriye, Akman-Demir, Gulsen, Allen, Alison B, Antel, Jack P, Antiguedad, Alfredo Rodriguez, Apperson, Michelle, Applebee, Angela M, Ayuso, Guillermo Izquierdo, Baba, Masayuki, Bajenaru, Ovidiu, Balasa, Rodica, Balci, Belgin Petek, Barnett, Michael, Bass, Ann, Becker, Veit U, Bejinariu, Mihaela, Bergh, Florian Then, Bergmann, Arnfin, Bernitsas, Evanthia, Berthele, Achim, Bhan, Virender, Bischof, Felix, Bjork, Randall John, Blevins, Gregg, Boehringer, Matthias, Boerner, Thomas, Bonek, Robert, Bowen, James D, Bowling, Allen, Boyko, Alexey N, Boz, Cavit, Bracknies, Vera, Braune, Stefan, Brescia Morra, Vincenzo, Brochet, Bruno, Brola, Waldemar, Brownstone, Paul Kenneth, Brozman, Miroslav, Brunet, Donald, Buraga, Ioan, Burnett, Margaret, Buttmann, Mathias, Butzkueven, Helmut, Cahill, Jonathan, Calkwood, Jonathan C, Camu, William, Cascione, Mark, Castelnovo, Giovani, Centonze, Diego, Cerqueira, Joao, Chan, Andrew, Cimprichova, Andrea, Cohan, Stanley, Comi, Giancarlo, Conway, Jill, Cooper, Joanna A, Corboy, John, Correale, Jorge, Costell, Brian, Cottrell, David A, Coyle, Patricia K, Craner, Matthew, Cui, Liying, Cunha, Luis, Czlonkowska, Anna, da Silva, Ana Martins, de Sa, Joao, de Seze, Jérôme, Debouverie, Marc, Debruyne, Jan, Decoo, Danny, Defer, Gilles, Derfuss, Tobias, Deri, Norma H, Dihenia, Bhupesh, Dioszeghy, Peter, Donath, Vladimir, Dubois, Benedicte, Duddy, Martin, Duquette, Pierre, Edan, Gilles, Efendi, Husnu, Elias, Stanton, Emrich, Peter J, Estruch, Bonaventura Casanova, Evdoshenko, Evgeniy P, Faiss, Juergen, Fedyanin, Alexander S, Feneberg, Wolfgang, Fermont, Jiske, Fernandez, Oscar Fernandez, Ferrer, Francisco Coret, Fink, Katharina, Ford, Helen, Ford, Corey, Francia, Ada, Freedman, Mark, Frishberg, Benjamin, Galgani, Simonetta, Garmany, George P, Gehring, Klaus, Gitt, Jeffrey, Gobbi, Claudio, Goldstick, Lawrence P, Gonzalez, Rafael Arroyo, Grandmaison, Francois, Grigoriadis, Nikolaos, Grigorova, Olga, Grimaldi, Luigi Maria Edoardo, Gross, Jeffrey, Gross-Paju, Katrin, Gudesblatt, Mark, Guillaume, Daniel, Haas, Judith, Hancinova, Viera, Hancu, Anca, Hardiman, Orla, Harmjanz, Arndt, Heidenreich, Fedor R, Hengstman, G J D, Herbert, Joseph, Herring, Mark, Hodgkinson, Suzanne, Hoffmann, Olaf M, Hofmann, Werner E, Honeycutt, William D, Hua, Le Hanh, Huang, Dehui, Huang, Yining, Huang, DeRen, Hupperts, Raymond, Imre, Piroska, Jacobs, Alan Keith, Jakab, Gabor, Jasinska, Elzbieta, Kaida, Kenichi, Kalnina, Jolanta, Kaprelyan, Ara, Karelis, Guntis, Karussis, Dimitrios, Katz, Amos, Khabirov, Farit A, Khatri, Bhupendra, Kimura, Takashi, Kister, Ilya, Kizlaitiene, Rasa, Klimova, Eleonora, Koehler, Juergen, Komatineni, Aparna, Kornhuber, Anselm, Kovacs, Krisztina, Koves, Agnes, Kozubski, Wojciech, Krastev, Georgi, Krupp, Lauren B, Kurca, Egon, Lassek, Christoph, Laureys, Guy, Lee, Liesly, Lensch, Eckart, Leutmezer, Fritz, Li, Hongzeng, Linker, Ralf A, Linnebank, Michael, Liskova, Petra, Llanera, Cristina, Lu, Jiahong, Lutterotti, Andreas, Lycke, Jan, Macdonell, Richard, Maciejowski, Maciej, Maeurer, Mathias, Magzhanov, Rim V, Maida, Eva-Maria, Malciene, Lina, Mao-Draayer, Yang, Marfia, Girolama Alessandra, Markowitz, Clyde, Mastorodimos, Vasileios, Matyas, Klotild, Meca-Lallana, Jose, Merino, Juan Antonio Garcia, Mihetiu, Ioan Gheorghe, Milanov, Ivan, Miller, Aaron E, Millers, Andrejs, Mirabella, Massimiliano, Mizuno, Masanori, Montalban, Xavier, Montoya, Lilina, Mori, Masahiro, Mueller, Stefanie, Nakahara, Jin, Nakatsuji, Yuji, Newsome, Scott, Nicholas, Richard, Nielsen, A Scott, Nikfekr, Esmaeil, Nocentini, Ugo, Nohara, Chiyoko, Nomura, Kyoichi, Odinak, Miroslav M, Olsson, Tomas, van Oosten, B W, Oreja-Guevara, Celia, Oschmann, Patrick, Overell, James, Pachner, Andrew, Panczel, Gyula, Pandolfo, Massimo, Papeix, Caroline, Patrucco, Liliana, Pelletier, Jean, Piedrabuena, Raul, Pless, Misha, Polzer, Udo, Pozsegovits, Krisztian, Rastenyte, Daiva, Rauer, Sebastian, Reifschneider, Gerd, Rey, Roberto, Rizvi, Syed A, Robertson, Derrick, Rodriguez, Jose Martinez, Rog, David, Roshanisefat, Homayoun, Rowe, Vernon, Rozsa, Csilla, Rubin, Susan, Rusek, Stanislaw, Saccà, Francesco, Saida, Takahiko, Salgado, Antonio Vasco, Sanchez, Victoria Eugenia Fernandez, Sanders, Kalina, Satori, Maria, Sazonov, Denis V, Scarpini, Elio Angelo, Schlegel, Eugen, Schluep, Myriam, Schmidt, Stephan, Scholz, Erich, Schrijver, H M, Schwab, Matthias, Schwartz, Raymond, Scott, James, Selmaj, Krzysztof, Shafer, Stuart, Sharrack, Basil, Shchukin, Ivan A, Shimizu, Yuko, Shotekov, Penko, Siever, Arno, Sigel, Karl-Otto, Silliman, Scott, Simo, Magdolna, Simu, Mihaela, Sinay, Vladimiro, Siquier, Antonio Escartin, Siva, Aksel, Skoda, Ondrej, Solomon, Andrew, Stangel, Martin, Stefoski, Dusan, Steingo, Brian, Stolyarov, Igor D, Stourac, Pavel, Strassburger-Krogias, Katrin, Strauss, Erik, Stuve, Olaf, Tarnev, Ivaylo, Tavernarakis, Antonios, Tello, Cristina Ramo, Terzi, Murat, Ticha, Veronika, Ticmeanu, Marina, Tiel-Wilck, Klaus, Toomsoo, Toomas, Tubridy, Niall, Tullman, Mark J, Tumani, Hayrettin, Turcani, Peter, Turner, Ben, Uccelli, Antonio, Urtaza, Francisco Javier Olascoaga, Vachova, Marta, Valikovics, Attila, Walter, Silke, Van Wijmeersch, Bart, Vanopdenbosch, Ludo, Weber, Joerg R, Weiss, Sara, Weissert, Robert, Vermersch, Patrick, West, Timothy, Wiendl, Heinz, Wiertlewski, Sandrine, Wildemann, Brigitte, Willekens, Barbara, Visser, L H, Vorobeychik, Galina, Xu, Xianhao, Yamamura, Takashi, Yang, Yi N, Yelamos, Sergio Martinez, Yeung, Michael, Zacharias, Alan, Zelkowitz, Marvin, Zettl, Uwe, Zhang, Meini, Zhou, Hongyu, Zieman, Ulf, Ziemssen, Tjalf, Kappos, Ludwig, Bar-Or, Amit, Cree, Bruce A C, Fox, Robert J, Giovannoni, Gavin, Gold, Ralf, Arnold, Douglas L, Arnould, Sophie, Scherz, Tatiana, Wolf, Christian, Wallström, Erik, and Dahlke, Frank

Published
2018
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5. Status of diagnostic approaches to AQP4-IgG seronegative NMO and NMO/MS overlap syndromes

Author

Juryńczyk, Maciej, Weinshenker, Brian, Akman-Demir, Gulsen, Asgari, Nasrin, Barnes, David, Boggild, Mike, Chaudhuri, Abhijit, D’hooghe, Marie, Evangelou, Nikos, Geraldes, Ruth, Illes, Zsolt, Jacob, Anu, Kim, Ho Jin, Kleiter, Ingo, Levy, Michael, Marignier, Romain, McGuigan, Christopher, Murray, Katy, Nakashima, Ichiro, Pandit, Lekha, Paul, Friedemann, Pittock, Sean, Selmaj, Krzysztof, de Sèze, Jérôme, Siva, Aksel, Tanasescu, Radu, Vukusic, Sandra, Wingerchuk, Dean, Wren, Damian, Leite, Isabel, and Palace, Jacqueline

Published
2016
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14. Inflammatory/demyelinating central nervous system involvement in familial Mediterranean fever (FMF): coincidence or association?

Author

Akman-Demir, Gulsen, Gul, Ahmet, Gurol, Edip, Ozdogan, Huri, Bahar, Sara, Oge, A. Emre, Gurvit, Hakan, Saruhan-Direskeneli, Guher, Yazici, Hasan, and Eraksoy, Mefkure

Subjects
Central nervous system diseases -- Risk factors, Central nervous system diseases -- Diagnosis, Central nervous system diseases -- Genetic aspects, Familial Mediterranean fever -- Diagnosis, Familial Mediterranean fever -- Development and progression, Familial Mediterranean fever -- Genetic aspects, Familial Mediterranean fever -- Complications and side effects, Health
Published
2006

16. Severe Optic Neuritis: 72 Cases from Turkey

Author

Isikay, Ilksen, BIÇAKCI, ŞEBNEM, ÇELEBİSOY, NEŞE, AKDAL HALMAGYI, GÜLDEN, YAMAN, AYLİN, SÖYLEV BAJIN, MELTEM FATMA, GÖKÇAY, FİGEN, Akman-Demir, Gulsen, Toydemir, Hulya Ertasoglu, and Altunrende, Burcu

Published
2018

18. Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis

Author

Hauser, Stephen L., Bar-Or, Amit, Comi, Giancarlo, Giovannoni, Gavin, Hartung, Hans-Peter, Hemmer, Bernhard, Lublin, Fred, Montalban, Xavier, Rammohan, Kottil W., Selmaj, Krzysztof, Traboulsee, Anthony, Wolinsky, Jerry S., Arnold, Douglas L., Klingelschmitt, Gaelle, Masterman, Donna, Fontoura, Paulo, Belachew, Shibeshih, Chin, Peter, Mairon, Nicole, Garren, Hideki, Kappos, Ludwig, And Opera Ii Clinical Investigators, Opera I., Reingold, Stephen C., Sandberg-Wollheim, Magnhild, Barkhof, Frederik, Dörmer, Thomas, Evans, Scott, Mcfarland, Henry F., Steiner, Israel, Yaldizli, Özgür, D Souza, Marcus, Andelova, Michaela, Rust, Heiko, Ballario, Carlos, Giannaula, Rolando, Reich, Edgardo Gabriel, Parratt, John, Eggers, Christian, Buyle, Maarten, Pesch, Vincent, Vanopdenbosch, Ludo, Carneiro, Denise, Friedrich, Mauricio, Longo, Alexandre Luiz, Genov, Krasimir, Ivanova, Sonya, Maslarov, Dimitar, Lilovski, Hristo, Staikov, Ivan, Cueto, German, Dufek, Michal, Havrdova, Eva, Novotna, Alena, Skoda, Ondrej, Talabova, Marika, Vachova, Marta, Gross-Paju, Katrin, Haldre, Sulev, Elovaara, Irina, Brochet, Bruno, Castelnovo, Giovanni, Clavelou, Pierre, Seze, Jerome, Debouverie, Marc, Braune, Stefan, Haas, Judith, Heidenreich, Fedor, Schwarz, Wolfgang, Siever, Arno, Urban, Peter Paul, Zettl, Uwe, Ziemann, Ulf, Ziemssen, Tjalf, Zipp, Frauke, Debreczeni, Robert, Rozsa, Csilla, Satori, Maria, Chapman, Joab, Ghezzi, Angelo, Perini, Paola, Pozzilli, Carlo, Kalnina, Jolanta, Millers, Andrejs, Budrys, Valmantas, Kizlaitiene, Rasa, Malciene, Lina, Vaitkus, Antanas, Castro Farfan, Guillermo, Gongora Rivera, Juan Fernando, Frequin, S. T. F. M., Gavidia Chucan, Jorge Martin, Perez Villegas, Julio, Pretell, Edwin Javier, Rodriguez Kadota, Liliana Elizabe, Fryze, Waldemar, Hertmanowska, Hanka, Maciejowski, Maciej, Opala, Grzegorz, Cerqueira, João, Arefieva, Elena, Maslova, Natalia, Odinak, Miroslav, Pankratov, Evgeny, Perfiliev, Semen, Poverennova, Irina, Sazonov, Denis, Shirshova, Elena, Sivertseva, Stella, Volkova, Larisa, Vorobyova, Olga, Knezevic, Zorica, Raicevic, Ranko, Vojinovic, Slobodan, Hancinova, Viera, Saffova, Patricia, Turcani, Peter, Vyletelka, Juraj, Coetzee, Christo C., Garcia-Merino, Antonio, Hernandez, Miguel A., Izquierdo Ayuso, Guillermo, Rodriguez Antigüedad, Alfredo, Gobbi, Claudio, Belal, Samir, Frih-Ayed, Mahbouba, Gouider, Riadh, Mrissa, Ridha, Sergii Moskovko, Sanotskyy, Yanosh, Sokolova, Larysa, Statinova, Olena, Voloshyna, Nataliya, Turner, Benjamin, Wilson, Martin, Applebee, Angela, Bandari, Daniel, Belkin, Martin, Birnbaum, Gary, Borresen, Thor, Boyd, James, Cascione, Mark, Cohan, Stanley, Cohen, Bruce, Conway, Jill, Cree, Bruce, Dihenia, Bhupesh, Dissin, Jonathan, Flitman, Stephen, Ford, Corey, Giancarlo, Thomas, Gold, Scott, Green, Barbara, Gwynn, Matthews, Honeycutt, David, Huddlestone, John, Klawiter, Eric, Kohrman, Bruce, Langer-Gould, Annette, Lava, Neil, Lindsey, William, Mitchell, Galen, Naismith, Robert, Nicolas, Joseph, Pardo, Gabriel, Patel, Malti, Porter, John A. H., Racke, Michael, Robertson, Derrick, Rossman, Howard, Schafer, John, Shubin, Richard, Singer, Barry, Smith, Charles, Suski, Valerie, Thrower, Ben, Wilson, Christopher, Wynn, Daniel, Zabad, Rana, Estol, Conrado J., Scarlatti, Annita, Alekseenko, Yuri, Fedulau, Aliaksandr, Kulesh, Sergey, Navumava, Halina, Willekens, Barbara, Alajbegovic, Azra, Sinanovic, Osman, Christo, Paulo, Papais Alvarenga, Regina Maria, Pereira Damasceno, Benito, Baldaranov, Dimo, Grigorova, Olga, Haralanov, Lyubomir, Milanova, Milena, Ayotte, Charles, Blevins, Gregg, Freedman, Mark, Grand Maison, François, Jacques, François, Yeung, Michael, Basic, Silvio, Hajnsek, Sanja, Janko-Labinac, Dolores, Kidjemet Piskac, Spomenka, Benesova, Yvonne, Hradilek, Pavel, Brassat, David, Edan, Gilles, Hautecoeur, Patrick, Moreau, Thibault, Papeix, Caroline, Tourbah, Ayman, Vukusic, Sandra, Aktas, Orhan, Berthele, Achim, Bodenschatz, Ralf, Foerch, Christian, Hohlfeld, Reinhard, Landefeld, Harald, Lang, Michael, Platten, Michael, Puzich, Reinhard, Schmidt, Stephan, Tubridy, Niall, Ardito, Bonaventura, Capra, Ruggero, Centonze, Diego, Crociani, Paola, Danni, Maura, Grimaldi, Luigi, Gusmaroli, Graziano, Mantegazza, Renato, Mirabella, Massimiliano, Uccelli, Antonio, Carbajal Ramirez, Angelica, Lopez Meza, Elmer Guillermo, Lopez Prieto, Juan Jose, Oropeza Alba, Jose Luis, Reyes-Morales, Sarug, San Juan Orta, Daniel, Myhr, Kjell Morten, Binek, Maciej, Czarnecki, Maciej, Klodowska-Duda, Gabriela, Stelmasiak, Zbigniew, Szczudlik, Andrzej, Tutaj, Andrzej, Belova, Anna, Dorogov, Nikolay, Fedyanin, Alexander, Khasanova, Dina, Makarov, Nikolay, Mishin, Gennadiy, Sherman, Mikhail, Skoromets, Alexander, Trushnikova, Tatiana, Donath, Vladimir, Dupejova, Beata, Gurcik, Ladislav, Arroyo, Rafael, Andres, Clara, Fernandez Fernandez, Oscar, Lainez Andrep, Jose Miguel, Martinez Gines, Maria Luisa, Martinez Rodriguez, Jose Enrique, Martinez Yelamos, Sergio, Oreja Guevara, Celia, Perez Sempere, Angel, Ramio, Luis, Ramo Tello, Cristina, Lycke, Jan, Olsson, Tomas, Roshanisefat, Homayoun, Sundström, Peter, Svenningsson, Anders, Akman Demir, Gulsen, Petek Balci, Belgin, Boz, Cavit, Efendi, Husnu, Karabudak, Rana, Siva, Aksel, Terzi, Murat, Yuceyar, Ayse Nur, Chmyr, Galyna, Goncharova, Yana, Kareta, Serhiy, Lutskiy, Igor, Harrower, Timothy, Hawkins, Clive, Pearson, Owen, Silber, Eli, Absher, John, Arnold, Thomas, Bass, Ann, Bernitsas, Evanthia, Braley, Tiffany, Calkwood, Jonathan, Carnes, Kenneth, Coyle, Patricia, Dunn, Jeffrey, Edwards, Keith, English, Jeffrey, Ferencz, Gerald, Fox, Edward, Frohman, Elliott, Gazda, Suzanne, Gitt, Jeffrey, Goodman, Andrew, Gross, Jeffrey, Hendin, Barry, Herrman, Craig, Hillen, Machteld, Huang, Deren, Hunter, Samuel, Hutton, George, Jacobs, Daniel, Keller, Bridget, Khan, Omar, Kister, Ilya, Krupp, Lauren, Lathi, Ellen, Lynch, Sharon, Miller, Tamara, Miravalle, Augusto, Omidvar, Omid, Perumal, Jai, Picone, Maryann, Rao, T. Hemanth, Repovic, Pavle, Riskind, Peter, Rowe, Vernon, Sheremata, William, Steingo, Brian, Twyman, Cary, Weisman, David, Wendt, Jeanette, Wray, Sibyl, Yapundich, Robert, Zarif, Myassar, Lääketieteen ja biotieteiden tiedekunta - Faculty of Medicine and Life Sciences, Tampere University, Hauser, S. L., Bar or, A., Comi, Giancarlo, Giovannoni, G., Hartung, H. . P., Hemmer, B., Lublin, F., Montalban, X., Rammohan, K. W., Selmaj, K., Traboulsee, A., Wolinsky, J. S., Arnold, D. L., Klingelschmitt, G., Masterman, D., Fontoura, P., Belachew, S., Chin, P., Mairon, N., Garren, H., Kappos, L., Universidade do Minho, Willekens, Barbara, and OPERA I and OPERA II Clinical Investigators

Subjects
0301 basic medicine, Male, Esclerosi múltiple, Adult, Antibodies, Monoclonal, Humanized, Antigens, CD20, B-Lymphocytes, Brain, Disease Progression, Female, Humans, Immunologic Factors, Infusions, Intravenous, Interferon-beta, Magnetic Resonance Imaging, Middle Aged, Multiple Sclerosis, Relapsing-Remitting, Recurrence, Medicine (all), Relapsing-Remitting, Gastroenterology, Medicina Clínica [Ciências Médicas], law.invention, 0302 clinical medicine, Immunologic Factor, Randomized controlled trial, law, Monoclonal, Clinical endpoint, Infusions, Intravenou, Immunologia, Humanized, Hazard ratio, B-Lymphocyte, General Medicine, Settore MED/26 - Neurologia, Intravenous, Neurotieteet - Neurosciences, medicine.drug, Human, medicine.medical_specialty, Infusions, Multiple Sclerosis, Immunology, Antibodies, Multiple sclerosis, 03 medical and health sciences, Internal medicine, medicine, CD20, Antigens, Ciências Médicas::Medicina Clínica, business.industry, Interferon beta-1a, medicine.disease, Confidence interval, Ocrelizumab, Interferon Beta-1a, Relapsing Multiple Sclerosis, 030104 developmental biology, Monoclonal antibodies, Human medicine, business, Anticossos monoclonals, 030217 neurology & neurosurgery
Abstract

BACKGROUND B cells influence the pathogenesis of multiple sclerosis. Ocrelizumab is a humanized monoclonal antibody that selectively depletes CD20+ B cells. METHODS In two identical phase 3 trials, we randomly assigned 821 and 835 patients with relapsing multiple sclerosis to receive intravenous ocrelizumab at a dose of 600 mg every 24 weeks or subcutaneous interferon beta-1a at a dose of 44 mu g three times weekly for 96 weeks. The primary end point was the annualized relapse rate. RESULTS The annualized relapse rate was lower with ocrelizumab than with interferon beta-1a in trial 1 (0.16 vs. 0.29; 46% lower rate with ocrelizumab; P, info:eu-repo/semantics/publishedVersion

Published
2017

19. Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

Author

Kappos, Ludwig, primary, Bar-Or, Amit, additional, Cree, Bruce A C, additional, Fox, Robert J, additional, Giovannoni, Gavin, additional, Gold, Ralf, additional, Vermersch, Patrick, additional, Arnold, Douglas L, additional, Arnould, Sophie, additional, Scherz, Tatiana, additional, Wolf, Christian, additional, Wallström, Erik, additional, Dahlke, Frank, additional, Achiron, Anat, additional, Achtnichts, Lutz, additional, Agan, Kadriye, additional, Akman-Demir, Gulsen, additional, Allen, Alison B, additional, Antel, Jack P, additional, Antiguedad, Alfredo Rodriguez, additional, Apperson, Michelle, additional, Applebee, Angela M, additional, Ayuso, Guillermo Izquierdo, additional, Baba, Masayuki, additional, Bajenaru, Ovidiu, additional, Balasa, Rodica, additional, Balci, Belgin Petek, additional, Barnett, Michael, additional, Bass, Ann, additional, Becker, Veit U, additional, Bejinariu, Mihaela, additional, Bergh, Florian Then, additional, Bergmann, Arnfin, additional, Bernitsas, Evanthia, additional, Berthele, Achim, additional, Bhan, Virender, additional, Bischof, Felix, additional, Bjork, Randall John, additional, Blevins, Gregg, additional, Boehringer, Matthias, additional, Boerner, Thomas, additional, Bonek, Robert, additional, Bowen, James D, additional, Bowling, Allen, additional, Boyko, Alexey N, additional, Boz, Cavit, additional, Bracknies, Vera, additional, Braune, Stefan, additional, Brescia Morra, Vincenzo, additional, Brochet, Bruno, additional, Brola, Waldemar, additional, Brownstone, Paul Kenneth, additional, Brozman, Miroslav, additional, Brunet, Donald, additional, Buraga, Ioan, additional, Burnett, Margaret, additional, Buttmann, Mathias, additional, Butzkueven, Helmut, additional, Cahill, Jonathan, additional, Calkwood, Jonathan C, additional, Camu, William, additional, Cascione, Mark, additional, Castelnovo, Giovani, additional, Centonze, Diego, additional, Cerqueira, Joao, additional, Chan, Andrew, additional, Cimprichova, Andrea, additional, Cohan, Stanley, additional, Comi, Giancarlo, additional, Conway, Jill, additional, Cooper, Joanna A, additional, Corboy, John, additional, Correale, Jorge, additional, Costell, Brian, additional, Cottrell, David A, additional, Coyle, Patricia K, additional, Craner, Matthew, additional, Cui, Liying, additional, Cunha, Luis, additional, Czlonkowska, Anna, additional, da Silva, Ana Martins, additional, de Sa, Joao, additional, de Seze, Jérôme, additional, Debouverie, Marc, additional, Debruyne, Jan, additional, Decoo, Danny, additional, Defer, Gilles, additional, Derfuss, Tobias, additional, Deri, Norma H, additional, Dihenia, Bhupesh, additional, Dioszeghy, Peter, additional, Donath, Vladimir, additional, Dubois, Benedicte, additional, Duddy, Martin, additional, Duquette, Pierre, additional, Edan, Gilles, additional, Efendi, Husnu, additional, Elias, Stanton, additional, Emrich, Peter J, additional, Estruch, Bonaventura Casanova, additional, Evdoshenko, Evgeniy P, additional, Faiss, Juergen, additional, Fedyanin, Alexander S, additional, Feneberg, Wolfgang, additional, Fermont, Jiske, additional, Fernandez, Oscar Fernandez, additional, Ferrer, Francisco Coret, additional, Fink, Katharina, additional, Ford, Helen, additional, Ford, Corey, additional, Francia, Ada, additional, Freedman, Mark, additional, Frishberg, Benjamin, additional, Galgani, Simonetta, additional, Garmany, George P, additional, Gehring, Klaus, additional, Gitt, Jeffrey, additional, Gobbi, Claudio, additional, Goldstick, Lawrence P, additional, Gonzalez, Rafael Arroyo, additional, Grandmaison, Francois, additional, Grigoriadis, Nikolaos, additional, Grigorova, Olga, additional, Grimaldi, Luigi Maria Edoardo, additional, Gross, Jeffrey, additional, Gross-Paju, Katrin, additional, Gudesblatt, Mark, additional, Guillaume, Daniel, additional, Haas, Judith, additional, Hancinova, Viera, additional, Hancu, Anca, additional, Hardiman, Orla, additional, Harmjanz, Arndt, additional, Heidenreich, Fedor R, additional, Hengstman, G J D, additional, Herbert, Joseph, additional, Herring, Mark, additional, Hodgkinson, Suzanne, additional, Hoffmann, Olaf M, additional, Hofmann, Werner E, additional, Honeycutt, William D, additional, Hua, Le Hanh, additional, Huang, Dehui, additional, Huang, Yining, additional, Huang, DeRen, additional, Hupperts, Raymond, additional, Imre, Piroska, additional, Jacobs, Alan Keith, additional, Jakab, Gabor, additional, Jasinska, Elzbieta, additional, Kaida, Kenichi, additional, Kalnina, Jolanta, additional, Kaprelyan, Ara, additional, Karelis, Guntis, additional, Karussis, Dimitrios, additional, Katz, Amos, additional, Khabirov, Farit A, additional, Khatri, Bhupendra, additional, Kimura, Takashi, additional, Kister, Ilya, additional, Kizlaitiene, Rasa, additional, Klimova, Eleonora, additional, Koehler, Juergen, additional, Komatineni, Aparna, additional, Kornhuber, Anselm, additional, Kovacs, Krisztina, additional, Koves, Agnes, additional, Kozubski, Wojciech, additional, Krastev, Georgi, additional, Krupp, Lauren B, additional, Kurca, Egon, additional, Lassek, Christoph, additional, Laureys, Guy, additional, Lee, Liesly, additional, Lensch, Eckart, additional, Leutmezer, Fritz, additional, Li, Hongzeng, additional, Linker, Ralf A, additional, Linnebank, Michael, additional, Liskova, Petra, additional, Llanera, Cristina, additional, Lu, Jiahong, additional, Lutterotti, Andreas, additional, Lycke, Jan, additional, Macdonell, Richard, additional, Maciejowski, Maciej, additional, Maeurer, Mathias, additional, Magzhanov, Rim V, additional, Maida, Eva-Maria, additional, Malciene, Lina, additional, Mao-Draayer, Yang, additional, Marfia, Girolama Alessandra, additional, Markowitz, Clyde, additional, Mastorodimos, Vasileios, additional, Matyas, Klotild, additional, Meca-Lallana, Jose, additional, Merino, Juan Antonio Garcia, additional, Mihetiu, Ioan Gheorghe, additional, Milanov, Ivan, additional, Miller, Aaron E, additional, Millers, Andrejs, additional, Mirabella, Massimiliano, additional, Mizuno, Masanori, additional, Montalban, Xavier, additional, Montoya, Lilina, additional, Mori, Masahiro, additional, Mueller, Stefanie, additional, Nakahara, Jin, additional, Nakatsuji, Yuji, additional, Newsome, Scott, additional, Nicholas, Richard, additional, Nielsen, A Scott, additional, Nikfekr, Esmaeil, additional, Nocentini, Ugo, additional, Nohara, Chiyoko, additional, Nomura, Kyoichi, additional, Odinak, Miroslav M, additional, Olsson, Tomas, additional, van Oosten, B W, additional, Oreja-Guevara, Celia, additional, Oschmann, Patrick, additional, Overell, James, additional, Pachner, Andrew, additional, Panczel, Gyula, additional, Pandolfo, Massimo, additional, Papeix, Caroline, additional, Patrucco, Liliana, additional, Pelletier, Jean, additional, Piedrabuena, Raul, additional, Pless, Misha, additional, Polzer, Udo, additional, Pozsegovits, Krisztian, additional, Rastenyte, Daiva, additional, Rauer, Sebastian, additional, Reifschneider, Gerd, additional, Rey, Roberto, additional, Rizvi, Syed A, additional, Robertson, Derrick, additional, Rodriguez, Jose Martinez, additional, Rog, David, additional, Roshanisefat, Homayoun, additional, Rowe, Vernon, additional, Rozsa, Csilla, additional, Rubin, Susan, additional, Rusek, Stanislaw, additional, Saccà, Francesco, additional, Saida, Takahiko, additional, Salgado, Antonio Vasco, additional, Sanchez, Victoria Eugenia Fernandez, additional, Sanders, Kalina, additional, Satori, Maria, additional, Sazonov, Denis V, additional, Scarpini, Elio Angelo, additional, Schlegel, Eugen, additional, Schluep, Myriam, additional, Schmidt, Stephan, additional, Scholz, Erich, additional, Schrijver, H M, additional, Schwab, Matthias, additional, Schwartz, Raymond, additional, Scott, James, additional, Selmaj, Krzysztof, additional, Shafer, Stuart, additional, Sharrack, Basil, additional, Shchukin, Ivan A, additional, Shimizu, Yuko, additional, Shotekov, Penko, additional, Siever, Arno, additional, Sigel, Karl-Otto, additional, Silliman, Scott, additional, Simo, Magdolna, additional, Simu, Mihaela, additional, Sinay, Vladimiro, additional, Siquier, Antonio Escartin, additional, Siva, Aksel, additional, Skoda, Ondrej, additional, Solomon, Andrew, additional, Stangel, Martin, additional, Stefoski, Dusan, additional, Steingo, Brian, additional, Stolyarov, Igor D, additional, Stourac, Pavel, additional, Strassburger-Krogias, Katrin, additional, Strauss, Erik, additional, Stuve, Olaf, additional, Tarnev, Ivaylo, additional, Tavernarakis, Antonios, additional, Tello, Cristina Ramo, additional, Terzi, Murat, additional, Ticha, Veronika, additional, Ticmeanu, Marina, additional, Tiel-Wilck, Klaus, additional, Toomsoo, Toomas, additional, Tubridy, Niall, additional, Tullman, Mark J, additional, Tumani, Hayrettin, additional, Turcani, Peter, additional, Turner, Ben, additional, Uccelli, Antonio, additional, Urtaza, Francisco Javier Olascoaga, additional, Vachova, Marta, additional, Valikovics, Attila, additional, Walter, Silke, additional, Van Wijmeersch, Bart, additional, Vanopdenbosch, Ludo, additional, Weber, Joerg R, additional, Weiss, Sara, additional, Weissert, Robert, additional, West, Timothy, additional, Wiendl, Heinz, additional, Wiertlewski, Sandrine, additional, Wildemann, Brigitte, additional, Willekens, Barbara, additional, Visser, L H, additional, Vorobeychik, Galina, additional, Xu, Xianhao, additional, Yamamura, Takashi, additional, Yang, Yi N, additional, Yelamos, Sergio Martinez, additional, Yeung, Michael, additional, Zacharias, Alan, additional, Zelkowitz, Marvin, additional, Zettl, Uwe, additional, Zhang, Meini, additional, Zhou, Hongyu, additional, Zieman, Ulf, additional, and Ziemssen, Tjalf, additional

Published
2018
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21. Autoantibodies to neuronal surface antigens in thyroid antibody-positive and -negative limbic encephalitis

Author

Tuzun, Erdem, Erdag, Ece, Durmus, Hacer, Brenner, Tanja, Turkoglu, Recai, Kurtuncu, Murat, Lang, Bethan, Akman-Demir, Gulsen, Eraksoy, Mefkure, and Vincent, Angela

Subjects
Potassium channels -- Physiological aspects -- Genetic aspects -- Research, Encephalitis -- Diagnosis -- Risk factors -- Genetic aspects -- Care and treatment -- Research, Autoantibodies -- Health aspects, Health
Abstract

Byline: Erdem. Tuzun, Ece. Erdag, Hacer. Durmus, Tanja. Brenner, Recai. Turkoglu, Murat. Kurtuncu, Bethan. Lang, Gulsen. Akman-Demir, Mefkure. Eraksoy, Angela. Vincent Background : Thyroid antibodies (Thy-Abs) are frequently detected in [...]

Published
2011

23. A 12-month, Open Label, Multicenter Pilot Study Evaluating Fingolimod Treatment in terms of Patient Satisfaction in Relapsing Remitting Multiple Sclerosis Patients - FINE Trial

Author

AKMAN DEMIR, Gulsen, primary, TURKOGLU, Recai, additional, SAIP, Sabahattin, additional, YUCEYAR, Nur, additional, EFENDI, Husnu, additional, TURAN, Omer Faruk, additional, AGAN, Kadriye, additional, TERZI, Murat, additional, BOZ, Cavit, additional, TUNCER, Asli, additional, KOCER, Belgin, additional, KASAP, Mithat, additional, CALISKAN, Zeynep, additional, and Study Group, FINE, additional

Published
2017
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25. Does FMF gene exist in multiple sclerosis and contribute to the progression?

Author

Ozaras, Nihal, Akman-Demir, Gulsen, Ustek, Duran, Eraksoy, Mefkure, Abaci, Neslihan, and Ahmet Gül

Subjects
Ozaras N., Akman-Demir G., Ustek D., Eraksoy M., Abaci N., Gül A., -Does FMF gene exist in multiple sclerosis and contribute to the progression?-, NEUROLOGY ASIA, cilt.19, ss.235-236, 2014
Published
2014

26. Diagnosis and management of Neuro-Beh double dagger et's disease: international consensus recommendations

Author

Kalra, Seema Silman, Alan Akman-Demir, Gulsen Bohlega, Saeed and Borhani-Haghighi, Afshin Constantinescu, Cris S. Houman, Habib Mahr, Alfred Salvarani, Carlos Sfikakis, Petros P. and Siva, Aksel Al-Araji, Adnan

Subjects
lipids (amino acids, peptides, and proteins)
Abstract

Neuro-Beh double dagger et’s disease (NBD) is one of the more serious manifestations of Beh double dagger et’s disease (BD), which is a relapsing inflammatory multisystem disease with an interesting epidemiology. Though NBD is relatively uncommon, being potentially treatable, neurologists need to consider it in the differential diagnosis of inflammatory, infective, or demyelinating CNS disorders. Evidence-based information on key issues of NBD diagnosis and management is scarce, and planning for such studies is challenging. We therefore initiated this project to develop expert consensus recommendations that might be helpful to neurologists and other clinicians, created through an extensive literature review and wide consultations with an international advisory panel, followed by a Delphi exercise. We agreed on consensus criteria for the diagnosis of NBD with two levels of certainty in addition to recommendations on when to consider NBD in a neurological patient, and on the use of various paraclinical tests. The management recommendations included treatment of the parenchymal NBD and cerebral venous thrombosis, the use of disease modifying therapies, prognostic factors, outcome measures, and headache in BD. Future studies are needed to validate the proposed criteria and provide evidence-based treatments.

Published
2014

27. INTERNATIONAL CONSENSUS PROJECT: NEURO-BEHCET DISEASE

Author

Kalra, Seema Silman, Alan Akman-Demir, Gulsen Bohlega, Saeed and Bohrani-Haghighi, Afshin Constantinescu, Cris Houman, Habib and Mahr, Alfred Salvarani, Carlos Sfikakis, Petros P. Siva, A. Al-Araji, A.

Published
2014

29. Chronic Demyelinating Polyradiculoneuropathy Associated with -Human Immunodeficiency Virus- Infection: Different Clinical Features and Diagnostic Problems

Author

Kaymaz, Aysenur, Akman-Demir, Gulsen, Gungor-Tuncer, Ozlem, Tuncer, Serdar, Altunrende, Burcu, Matur, ZELİHA, ÖGE, Ali Emre, and MATUR, ZELİHA

Subjects
Different Clinical Features and Diagnostic Problems-, JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.30, sa.4, ss.805-813, 2013 [Matur Z., Kaymaz A., Altunrende B., Tuncer S., Gungor-Tuncer O., Akman-Demir G., ÖGE A. E. , -Chronic Demyelinating Polyradiculoneuropathy Associated with -Human Immunodeficiency Virus- Infection]
Abstract

During the course of human immunodeficiency virus (HIV) infection, which leads to a chronic infectious disease that suppresses the cellular immune system, various types of peripheral neuropathies can be seen in different stages from seroconversion to the advanced stage. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) usually occurs in early or mid-stage of the disease. In this study, we are presenting a 66 year-old man who was admitted to our clinic due to progressive and predominantly sensorial symptoms and signs of CIDP, who had recently been operated for carpal tunnel syndrome which was suggested by electromyography even though he had complains of diffuse polyneuropathy symptoms from the beginning. During his diagnostic work-up cerebrospinal fluid (CSF) analysis had revealed elevated protein and pleocytosis, and further investigation revealed HIV-1 infection. Areas of demyelination are very common in usual entrapment zones in the course of CIDP, which is a neuropathy with multi-segment demyelination in peripheral nerves and/nerve roots. Without a detailed patient history and examination, and a detailed EMG evaluation, a diffuse neuropathy can be misdiagnosed as an entrapment neuropathy. As it is in our case, this can lead to an unnecessary surgery and a delay in the actual diagnosis. CSF examination is very valuable for the investigation of the etiology of chronic demyelinating polyneuropaties. In CIDP patients, only protein elevation can be seen in CSF analysis; however, in the presence of pleocytosis, other diseases such as chronic infections, particularly HIV infection, other chronic inflammatory diseases, and malignant infiltration of nerve roots should be investigated.

Published
2013

30. Status of diagnostic approaches to AQP4-IgG seronegative NMO and NMO/MS overlap syndromes

Author

Juryńczyk, Maciej, primary, Weinshenker, Brian, additional, Akman-Demir, Gulsen, additional, Asgari, Nasrin, additional, Barnes, David, additional, Boggild, Mike, additional, Chaudhuri, Abhijit, additional, D’hooghe, Marie, additional, Evangelou, Nikos, additional, Geraldes, Ruth, additional, Illes, Zsolt, additional, Jacob, Anu, additional, Kim, Ho Jin, additional, Kleiter, Ingo, additional, Levy, Michael, additional, Marignier, Romain, additional, McGuigan, Christopher, additional, Murray, Katy, additional, Nakashima, Ichiro, additional, Pandit, Lekha, additional, Paul, Friedemann, additional, Pittock, Sean, additional, Selmaj, Krzysztof, additional, de Sèze, Jérôme, additional, Siva, Aksel, additional, Tanasescu, Radu, additional, Vukusic, Sandra, additional, Wingerchuk, Dean, additional, Wren, Damian, additional, Leite, Isabel, additional, and Palace, Jacqueline, additional

Published
2015
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34. INTERNATIONAL CONSENSUS PROJECT: NEURO-BEHCET DISEASE

Author

Kalra, Seema, primary, Silman, Alan, additional, Akman-Demir, Gulsen, additional, Bohlega, Saeed, additional, Bohrani-Haghighi, Afshin, additional, Constantinescu, Cris, additional, Houman, Habib, additional, Mahr, Alfred, additional, Salvarani, Carlos, additional, Sfikakis, Petros P, additional, Siva, A, additional, and Al-Araji, A, additional

Published
2014
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35. Uveitis as a prognostic factor in multiple sclerosis

Author

Shugaiv, Erkingul, primary, Tüzün, Erdem, additional, Kürtüncü, Murat, additional, Kıyat-Atamer, Aslı, additional, Çoban, Arzu, additional, Akman-Demir, Gulsen, additional, Tugal-Tutkun, Ilknur, additional, and Eraksoy, Mefkure, additional

Published
2014
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37. Diagnosis and management of Neuro-Behçet’s disease: international consensus recommendations

Author

Kalra, Seema, primary, Silman, Alan, additional, Akman-Demir, Gulsen, additional, Bohlega, Saeed, additional, Borhani-Haghighi, Afshin, additional, Constantinescu, Cris S., additional, Houman, Habib, additional, Mahr, Alfred, additional, Salvarani, Carlos, additional, Sfikakis, Petros P., additional, Siva, Aksel, additional, and Al-Araji, Adnan, additional

Published
2013
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39. Novel Anti-Neuronal Antibodies in Neuromyelitis Optica Patients with or without Aquaporin-4 Antibodies (P02.135)

Author

Cavus, Filiz, primary, Ugurel, Elif, additional, Sehitoglu, Elcin, additional, Woodhall, Mark, additional, Waters, Patrick, additional, Ulusoy, Canan, additional, Turan, Selin, additional, Vural, Burcak, additional, Turkoglu, Recai, additional, Eraksoy, Mefkure, additional, Vincent, Angela, additional, Akman-Demir, Gulsen, additional, and Tuzun, Erdem, additional

Published
2013
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40. Characterization of NMO and NMOSD Patients with a Late Onset (P02.152)

Author

Collongues, Nicolas, primary, Marignier, Romain, additional, Jacob, Anu, additional, Siva, Aksel, additional, Paul, Friedemann, additional, Zephir, Helene, additional, Leite, Maria Isabel, additional, Akman-Demir, Gulsen, additional, Elsone, Liene, additional, Jarius, Sven, additional, Papeix, Caroline, additional, Mutch, Kerry, additional, Saip, Sabahattin, additional, Wildemann, Brigitte, additional, Kitley, Joanna, additional, Karabudak, Rana, additional, Aktas, Orhan, additional, Kuscu, Demet, additional, Altintas, Ayse, additional, Palace, Jacqueline, additional, Confavreux, Christian, additional, and De Seze, Jerome, additional

Published
2013
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41. Progressive Encephalomyelitis with Rigidity and Myoclonus: A Syndrome with Diverse Clinical Features and Antibody Responses

Author

Shugaiv, Erkingül, primary, Leite, Maria Isabel, additional, Şehitoğlu, Elçin, additional, Woodhall, Mark, additional, Çavuş, Filiz, additional, Waters, Patrick, additional, İçöz, Sema, additional, Birişik, Ömer, additional, Uğurel, Elif, additional, Ulusoy, Canan, additional, Kürtüncü, Murat, additional, Vural, Burçak, additional, Vincent, Angela, additional, Akman-Demir, Gulsen, additional, and Tüzün, Erdem, additional

Published
2013
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43. Cognitive Impairment in Neuro-Behcet's Disease and Multiple Sclerosis: A Comparative Study

Author

Gündüz, Tuncay, primary, Emir, Özgür, additional, Kürtüncü, Murat, additional, Mutlu, Melike, additional, Tumaç, Ayfer, additional, Akca, Şükriye, additional, Çoban, Oğuzhan, additional, Bahar, Sara, additional, Öktem-Tanör, Öget, additional, Tüzün, Erdem, additional, Eraksoy, Mefkure, additional, Gürvit, Hakan, additional, and Akman-Demir, Gulsen, additional

Published
2012
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46. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease

Author

Remmers, Elaine F, primary, Cosan, Fulya, additional, Kirino, Yohei, additional, Ombrello, Michael J, additional, Abaci, Neslihan, additional, Satorius, Colleen, additional, Le, Julie M, additional, Yang, Barbara, additional, Korman, Benjamin D, additional, Cakiris, Aris, additional, Aglar, Oznur, additional, Emrence, Zeliha, additional, Azakli, Hulya, additional, Ustek, Duran, additional, Tugal-Tutkun, Ilknur, additional, Akman-Demir, Gulsen, additional, Chen, Wei, additional, Amos, Christopher I, additional, Dizon, Michael B, additional, Kose, Afet Akdag, additional, Azizlerli, Gulsevim, additional, Erer, Burak, additional, Brand, Oliver J, additional, Kaklamani, Virginia G, additional, Kaklamanis, Phaedon, additional, Ben-Chetrit, Eldad, additional, Stanford, Miles, additional, Fortune, Farida, additional, Ghabra, Marwen, additional, Ollier, William E R, additional, Cho, Young-Hun, additional, Bang, Dongsik, additional, O'Shea, John, additional, Wallace, Graham R, additional, Gadina, Massimo, additional, Kastner, Daniel L, additional, and Gül, Ahmet, additional

Published
2010
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49. Frequency and syndrome specificity of antibodies to aquaporin-4 in neurological patients with rheumatic disorders.

Author

Jarius, Sven, Jacobi, Christian, de Seze, Jerome, Zephir, Helene, Paul, Friedemann, Franciotta, Diego, Rommer, Paulus, Mader, Simone, Kleiter, Ingo, Reindl, Markus, Akman-Demir, Gulsen, Seifert-Held, Thomas, Kristoferitsch, Wolfgang, Melms, Arthur, Wandinger, Klaus-Peter, and Wildemann, Brigitte

Subjects
IMMUNOGLOBULINS, AQUAPORINS, NEUROLOGICAL disorders, CONNECTIVE tissue diseases, NEUROBEHAVIORAL disorders, RHEUMATISM, SCLERODERMA (Disease), DIAGNOSIS, PATIENTS
Abstract

Background: A new autoantibody (termed NMO-IgG, or AQP4-Ab) has recently been described in patients with neuromyelitis optica (NMO) and its formes frustes, longitudinally extensive transverse myelitis (LETM) and recurrent optic neuritis (rON). However, AQP4-Ab has been found also in patients with co-existing rheumatic diseases such as systemic lupus erythematosus (SLE) or Sjögren’s syndrome (SS), conditions which are characterized by broad, polyspecific B cell activation.Objectives: In this study, we aimed at evaluating the syndrome specificity and frequency of AQP4-Ab in patients with rheumatic diseases and neurological symptoms.Methods: For this purpose, serum samples from 109 neurological patients with established connective tissue disorders (CTD) (n = 54), possible CTD (n = 42), or vasculitis (n = 13) were analysed for the presence of AQP4-Ab by a cell-based assay employing recombinant human AQP4.Results: AQP4-Ab was detectable in 31/40 (78%) patients with CTD and NMO spectrum disorders (median titre, 1:1000) but in none of the samples obtained from patients with CTD or vasculitis and neurological disorders other than NMO, LETM, or rON (n = 69).Conclusion: The high syndrome specificity of the antibody for neuromyelitis optica spectrum disorders (NMOSDs) in patients with CTD supports the concept of AQP4-Ab being involved in the pathogenesis of these neurological conditions, and argues against AQP4-Ab simply being part of the polyclonal B cell activation generally associated with rheumatic diseases. Moreover, the finding that AQP4-Ab is present in patients with CTD and co-existing NMOSD with approximately the same frequency as in patients without CTD strengthens the case of CTD and AQP4-Ab positive NMOSD representing two co-existing yet distinct entities in the majority of patients. [ABSTRACT FROM AUTHOR]

Published
2011
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50. Uveitis as a prognostic factor in multiple sclerosis.

Author

Shugaiv, Erkingul, Tüzün, Erdem, Kürtüncü, Murat, Kıyat-Atamer, Aslı, Çoban, Arzu, Akman-Demir, Gulsen, Tugal-Tutkun, Ilknur, and Eraksoy, Mefkure

Subjects
UVEITIS, EYE inflammation, MULTIPLE sclerosis, PROGNOSIS, DEMYELINATION, MYELIN sheath diseases, PATIENTS
Abstract

Uveitis is occasionally encountered in multiple sclerosis (MS) patients. The objective of this report is to investigate whether uveitis has a prognostic impact on the clinical course of MS. Several clinical and demographic features were compared between 41 MS patients with uveitis and 100 randomly selected MS patients without uveitis. While there were no significant differences by means of gender, age of MS onset, oligoclonal band positivity and disease duration, EDSS and progression index (PI) scores of MS patients with uveitis were significantly lower than those without uveitis (p = 0.004 and <0.001, respectively). Our results suggest that uveitis might be used as a good prognostic factor. [ABSTRACT FROM PUBLISHER]

Published
2015
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