1. Inflammatory indexes predict mortality in non-malignant patients in palliative care.
- Author
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Ceylan, Serdar, Akkurt, Abbas Faruk, Gurses, Mehtap, Aydemir, Ayfer, Dede, Taylan Ozgur, Acaroglu, Ruya, and Duran Ugur, Fatma Utkan
- Subjects
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RISK assessment , *CROSS-sectional method , *PALLIATIVE treatment , *MULTIPLE regression analysis , *NEUTROPHILS , *HOSPITAL mortality , *BLOOD cell count , *RETROSPECTIVE studies , *DESCRIPTIVE statistics , *MANN Whitney U Test , *CHI-squared test , *MEDICAL records , *ACQUISITION of data , *STATISTICS , *INFLAMMATION , *HOSPITAL care of older people , *DATA analysis software , *LENGTH of stay in hospitals , *DEMENTIA , *ALBUMINS , *STROKE , *BIOMARKERS , *PROPORTIONAL hazards models , *C-reactive protein - Abstract
Background: The literature on the use of inflammatory indexes for palliative care patients without malignancy is scarce. Aims: To determine which inflammatory indexes are associated with the mortality risks of non-malignant patients hospitalised and receiving palliative care. Methods: Discharged or deceased patients in a palliative care unit of a secondary care hospital were included. The laboratory values were obtained during the first 48 hours of hospitalisation. Findings: As a result of univariate Cox regression analysis, 14-day mortality rate was affected by lymphocyte ratio, neutrophil-to-albumin ratio (NAR), C-reactive protein/albumin ratio (CAR), multi-inflammatory indexes (MII-1) and MII-2 (p<0.001, p=0.001, p=0.002, p=0.009 and p=0.003, respectively); NLR, CLR, NAR, CAR, MII-1 and MII-2 (respectively p=0.005, p<0.001, p<0.001, p<0.001, p=0.001 and p<0.001) affected 28-day mortality rate. Indexes that statistically significantly increased both 14-day and 28-day mortality rates independently of other variables were CLR, NAR, CAR, MII-1 and MII-2. Conclusion: High values in inflammatory indexes, including C-reactive protein and albumin increase the risk of 14-day and 28-day mortality rates in palliative care non-malignant patients. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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