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2. A Comparative Study Between Cefminox (MT-141) and Cefotaxime in Respiratory Tract Infections

Author

Fumio MIKI, Eiji INOUE, Masakazu TERAGAKI, Kaname AKIOKA, Minoru YOSHIYAMA, Toru HIRAGA, Tetsuto MURATA, Akira SAITO, Akira UJIIE, Morikuni ABE, Yoshinobu TAKASHIRO, Ichiro NAKAYAMA, Masumi TOMIZAWA, Fumio NAGAHAMA, Takehito NAKABAYASHI, Tetsuji KOROKU, Yomei HIRAGA, Katsuo SUZUKI, Hiroshi KON, Yasumasa YOKOTA, Ryoji OHASHI, Jutaro SHIMOMURA, Yoichi GOCHO, Hisashi NISHIHARA, Kazuo TAKEBE, Mitsuo MASUDA, Seiichi MURAKAMI, Yoshihiro KUMASAKA, Mitsuo NAKAMURA, Tatsuro IRIE, Masashi YONEDA, Tamotsu TAKISHIMA, Yasuo TANNO, Kiyoshi KONNO, Kotaru OIZUMI, Seiichi AONUMA, Izumi HAYASHI, Tatsuya ABE, Masataka KATSU, Hisashi TAKIZUKA, Reiko SAITO, Keimei MASHIMO, Tetsuro UKAI, Hiroichi TANIMOTO, Ryuoh NAKATANI, Kunihiko YOSHIMURA, Yoshitaka NAKAMORI, Naohiko CHONABAYASHI, Koichiro NAKATA, Junzaburo KABE, Hiroyoshi ISHIBASHI, Yasuyuki SANO, Hideo IKEMOTO, Kazuyoshi WATANABE, Atsushi SAITO, Keiichi NAKAGAWA, Kentaro WATANABE, Masaru KOYAMA, Hiroyuki KOBAYASHI, Kota KONO, Kenji TAKAMURA, Hiroshi OSHITANI, Kokichi FUKUSHIMA, Akira ITO, Shigeki ODAGIRI, Hirotada IKEDA, Kaneo SUZUKI, Kou MUROHASHI, Tamotsu KANEKO, Keinosuke NOSE, Kazufuto FUKAYA, Tadashi TAKIGAMI, Ippei FUJIMORI, Yoshio KOBAYASHI, Mitsuo OBANA, Hajimu TAKEDA, Fusanosuke YAMASAKU, Yasutoshi SUZUKI, Osamu SEKINE, Yoshimaru USUDA, Nobuki AOKI, Kaoru OYAMA, Toshihiko TAKEUCHI, Masahito KATO, Hidekazu HANAKI, Toshiyuki YAMAMOTO, Kanzo SUZUKI, Akihiko KISHIMOTO, Katsutaka TORIKAI, Mutsumi ASHIHARA, Tatsuo SUGIHARA, Nobuo MAEKAWA, Michiyasu NAKANISHI, Tsuneo MATSUBARA, Nobuaki IKEDA, Ataka SHIBATA, Kenji TAKAMATSU, Yuruko OKAMOTO, Keigo MAEHARA, Yube IIDA, Rinzo SOEJIMA, Yoshito NIKI, Chikara NAKAHAMA, Michifumi ADACHI, Osamu KURIMURA, Koji NOMA, Eiro TSUBURA, Masakazu TAMURA, Yoshiro SAWAE, Kaoru OKADA, Yukio KUMAGAI, Kenichi MATSUBA, Takahiro NAWATA, Masaro KAJI, Yoichiro ICHIKAWA, Nisaburo TANAKA, Toshiharu HAYASHI, Yoshiyuki MITSUTAKE, Kazuma FUJINO, Kohei HARA, Atushi SAITO, Keizo YAMAGUCHI, Yoji SUZUYAMA, Yoshiteru SHIGENO, Isao NAKAMURA, Munetaka KOMORI, Ken SHINZATO, Hirofumi OGATA, Naomi ITO, Keizo MATSUMOTO, Tsuyoshi NAGATAKE, Naoto RIKITOMI, Masayuki ANDO, Mineharu SUGIMOTO, Moritaka SUGA, Takashi ITOGA, Masaru NASU, Yoichiro GOTO, Jun GOTO, and Takayoshi TASHIRO

Subjects
Clinical Trials as Topic, medicine.medical_specialty, Cefotaxime, Respiratory tract infections, Cefminox, business.industry, Lung abscess, Pneumonia, General Medicine, medicine.disease, Gastroenterology, Chronic disease, Internal medicine, Chronic Disease, medicine, Humans, Cephamycins, Lung Abscess, business, Respiratory Tract Infections, medicine.drug
Published
1985
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3. Studies on the syntheses of heterocyclic compounds. Part DCXX. Total synthesis of (±)-orientalidine and a positional isomer

Author

Masataka Ihara, Tetsuji Kametani, Akira Ujiie, and Keiichiro Fukumoto

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, chemistry, Base (chemistry), medicine, Organic chemistry, Total synthesis, Dimethylformamide, Methylene, Chloride, medicine.drug, Sodium hydride
Abstract

The total synthesis of (±)-orientalidine (2) was accomplished by treatment of (±)-demethylmecambridine (3) with methylene chloride and sodium hydride in dimethylformamide. 11-Hydroxy-12-hydroxymethyl-3,10-dimethoxy-1,2-methylenedioxyberbine (16) was synthesised from 1-(3-benzyloxy-4-methoxybenzyl)-1,2,3,4-tetrahydro-6-methoxy-7,8-methylenedioxyisoquinoline (11) by way of 11-benzyloxy-3,10-dimethoxy-1,2-methylenedioxyberberine (12) and the corresponding phenolic base (15). Treatment of the hydroxymethylated berbines (5) and (16) under the same conditions as for the synthesis of orientalidine gave the corresponding berbines (6) and (18) containing a fused m-dioxin system.

Published
1975
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5. Comparative Study of the Effectiveness of Mezlocillin and Ampicillin on Respiratory Tract Infection

Author

Kuninori Suzuki, Fumiro Tanaka, Mikihiko Tango, Hidetoshi Shibaki, Tadanori Kondo, Tadashi Miyazawa, Osamu Hagiwara, Nobuki Aoki, Fumio Nagahama, Ryuzo Fueki, Kenzo Shiota, Hajime Watanabe, Shigechika Kado, Hideo Sasaki, Hiroshi Takagi, Osamu Kitamoto, Akira Kinoshita, Haruaki Ichimaru, Akihiko Kuze, Morikuni Abe, Yoshihiro Takihara, Yutaka Motohashi, Keimei Mashimo, Masao Nagasawa, Kanzo Suzuki, Tadashi Miyahara, Kyuichiro Sekine, Masumi Tomizawa, Shinya Yasuda, Kaori Yasuda, Hiroshi Suzuki, Hiroyuki Kobayashi, Masaru Koyama, Takashi Nakagawa, Naoyoshi Masaki, Sumio Yamaoka, Setsuo Kobayashi, Mitsuo Masuda, Yukio Nishimoto, Masataka Katsu, Kaoru Oyama, Fumio Miki, Munetaka Komori, Yoshiro Sawae, Tohru Nagasawa, Hiroshi Okubo, Norichika Matsumoto, Izumi Hayashi, Masakatsu Nishida, Kei Yaguchi, Kohzo Mori, Hiroichi Tanimoto, Kiyoshi Konno, Kohei Hara, Kokichi Fukushima, Ippei Fujimori, Hideo Ohzeki, Osamu Abe, Masao Nakatomi, Yoshihiro Kumasaka, Yuruko Okamoto, Masayuki Tachibana, Toyokazu Tamura, Masaro Kaji, Toshio Kobayashi, Akio Tachibana, Kazuo Kondo, Keiko Iwamoto, Norio Inaba, Kazuyoshi Watanabe, Kentaro Watanabe, Saburo Kurematsu, Keizo Matsumoto, Tetsuharu Tanaka, Tetsuo Komori, Yoshinobu Takashiro, Mitsuo Obana, Takahiko Konno, Sumio Arai, Chie Karibe, Junzaburo Kabe, Mitsuo Hase, Kunio Dobashi, Makio Kurihara, Toshihiro Goto, Masahisa Ohmori, Yoichi Miyahara, Fusanosuke Yamasaku, Akira Ujiie, Shinichi Tomioka, Naofumi Suyama, Tsugio Nakazawa, Hideo Aoki, Eiji Nakamura, Shigeru Matsumoto, Hiroshi Nagano, Akira Saito, Naomi Kodomari, Kazunori Harada, Shigeharu Morioka, Yomei Hiraga, Takehisa Yamaji, Kohya Shiba, Osamu Kurimura, Nobuo Maekawa, Kazutoyo Kaneko, Kozue Komori, Hidero Nakazono, Keiichi Nakagawa, Takashi Watanabe, Shuichiro Yoshida, Kotaro Oizumi, Kiyoko Sakai, Yoshito Niki, Yoichiro Ichikawa, Okui S, Takafumi Yano, Tsuneharu Baba, Kunihiko Shindo, Kazue Sadamoto, Rinzo Soejima, Michiyasu Nakanishi, Motoichi Tanaka, Takaaki Akagawa, Masafumi Kitaoka, Masami Arakawa, Katsuhiko Matsui, Hideyuki Hasegawa, Katsuhiro Okamoto, Hironobu Ihara, Toshiyuki Yamamoto, Toshio Hojo, Kenji Takamatsu, Jingoro Shimada, Kaoru Okada, Sumio Kishimoto, Hideo Ikemoto, Yasunori Tanaka, Hiroshi Minami, Yoshihiro Takishita, Hiroyasu Kawabe, Mitsuharu Ogi, Ryoichi Amitani, Mamoru Yamada, Yoshiro Mochizuki, Michio Yamakido, Eiro Tsubura, Shunji Hayashi, Akira Ito, Katsumi Endo, Fumiaki Uchihira, Takashi Akiyama, Ichiro Nakayama, Masami Ueda, Atsushi Shimomura, Yoshiro Oda, Hiroshi Fukui, Yuichi Koizumi, Kazuo Takebe, Ken-ichi Imamura, Kenji Saeki, Yasuyoshi Sakurai, Yayoi Okawa, Atsushi Saito, Takuro Matsumoto, Shigeki Odagiri, Ken Osonoi, Mitsuko Takamura, Tamotsu Takishima, Akio Aoyagi, Kazuki Konishi, Keigo Maehara, Tatsuo Saito, Koichiro Nakada, Tatsuya Ohnuki, Takehito Nakabayashi, Yoshio Kinoshita, Tadashi Takigami, Yoshimaru Usuda, Hiroyuki Doi, Kiyofumi Ishikawa, Akira Yokoyama, Seiichi Murakami, Yoshio Kobayashi, Osamu Sekine, Kawai M, Hisashi Nakahata, and Toshikazu Nemoto

Subjects
medicine.medical_specialty, Mezlocillin, medicine.anatomical_structure, business.industry, Internal medicine, Ampicillin, medicine, General Medicine, business, Gastroenterology, medicine.drug, Respiratory tract
Published
1981
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6. Comparative Study of the Effectiveness of Lenampicillin and Bacampicillin on Bacterial Pneumonia by Double Blind Method

Author

Fumio MIKI, Yosiyasu IKUNO, Eiji INOUE, Minoru YOSIYAMA, Tetsuto MURATA, Shin-ichi TANIZAWA, Kazuo SAKAMOTO, Hirozumi SAKAI, Akira SAITO, Masumi TOMIZAWA, Ichiro NAKAYAMA, Osamu YAJIMA, Akira UJIIE, Kazuo TAKEBE, Mitsuo MASUDA, Seiichi MURAKAMI, Takeshi OSONOI, Toshikazu MAEDA, Kazuo SASAKI, Kiyoshi KONNO, Kotaro OIZUMI, Seiichi AONUMA, Kosaku NAGAI, Tsukasa YOSHIDA, Syuji CHIBA, Kazuo SATO, Teruo HASUIKE, Shigeru TAMAKI, Izumi HAYASHI, Tadashi MIYAHARA, Atsushi SAITO, Hideo IKEMOTO, Kazuyoshi WATANABE, Kentaro WATANABE, Masaru KOYAMA, Fukuo IIJIMA, Kaoru SHIMADA, Takashi INAMATSU, Kyoko URAYAMA, Masataka KATSU, Hiroharu OGIHARA, Fuyuhiko HIGASHI, Toshio SEKIMOTO, Takeshi KAWAI, Akio ONAKA, Atsushi AJISAWA, Tetsuji KATAYAMA, Hayato MIYAJI, Yumiko MURAYAMA, Keimei MASHIMO, Chizuru ITO, Hiroichi TANIMOTO, Kunihiko YOSHIMURA, Naohiko CHONABAYASI, Tatsuo NAKATANI, Hiroyuki KOBAYASHI, Hiroshi OSHITANI, Junzaburo KABE, Hiroyoshi ISHIBASHI, Yasuyuki SANO, Ippei FUJIMORI, Yoshio KOBAYASHI, Yasushi NAKAMURA, Takao OKUBO, Akira ITO, Fumio MATSUMOTO, Kazufuto FUKAYA, Shigeki ODAGIRI, Hirotada IKEDA, Keinosuke NOSE, Kou MUROHASHI, Shin-ichiro WATANABE, Hajimu TAKEDA, Koichi WADA, Tomoko KABASAWA, Fusanosuke YAMASAKU, Yasutoshi SUZUKI, Osamu SEKINE, Nobuki AOKI, Kaoru OYAMA, Toshihiko TAKEUCHI, Masahito KATO, Hidekazu HANAKI, Ikuji USAMI, Hirohiko NAGASAKA, Yasuo YAMADA, Tsuyoshi ITO, Naohiko TERAO, Hideaki KUROKI, Toshiyuki YAMAMOTO, Nobuo MAEKAWA, Michiyasu NAKANISHI, Hideki NISHIYAMA, Takayoshi YAMAMOTO, Yasutaku SHIBATA, Hiroyuki TSUJINO, Riichiro MIKAMI, Masayoshi SAWAKI, Yuruko OKAMOTO, Yube IIDA, Keigo MAEHARA, Hiroshi OKUBO, Yoshihiro UEDA, Kenji TAKAMATSU, Rinzo SOEJIMA, Yoshihito NIKI, Yukio NISHIMOTO, Akimitsu KAMITSUNA, Shigekiyo NAKANISHI, Michio YAMAKIDO, Kenji HASEGAWA, Kazumasa NOUMI, Osamu KURIMURA, Tadashi MASUDA, Eiro TSUBURA, Masakazu TAMURA, Tadashi NAKAYAMA, Etsuo SENOO, Kenji TANI, Yuji HIGUCHI, Toshihiko KAMEI, Yoshiro SAWAE, Kaoru OKADA, Kohei HARA, Keizo YAMAGUCHI, Yoji SUZUYAMA, Yoshiteru SHIGENO, Kazuhiro OKUNO, Rokushi OKA, Keizo MATSUMOTO, Tsuyoshi MAGATAKE, Naoto RIKITOMI, Masato HAYASHI, Ken-ichi HOSOYA, Kiyoshi ZAYASU, Yoshiro ARAKI, Masayuki ANDO, Mineharu SUGIMOTO, Hiroaki NAOE, Yasutsugu FUKUDA, Katsumasa TOKUNAGA, Kiyoshi SHIMA, Sadanobu HIGUCHI, Takashi ITOGA, Masaru NASU, Jun GOTO, Yoichiro GOTO, Takayoshi TASHIRO, Kazumine KOBARI, and Masao NAKATOMI

Subjects
Adult, Male, Clinical Trials as Topic, medicine.medical_specialty, Adolescent, business.industry, Pneumonia, General Medicine, Middle Aged, medicine.disease, Gastroenterology, Double-Blind Method, Bacampicillin, Internal medicine, Humans, Medicine, Ampicillin, Female, business, Lenampicillin, Aged, medicine.drug
Published
1985
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7. Comparative Study on Sultamicillin and Bacampicillin in the Treatment of Respiratory Tract Infections

Author

Hiroyuki KOBAYASHI, Kenji TAKAMURA, Kota KONO, Tomoko NIHEI, Akira SAITO, Ichiro NAKAYAMA, Akira UJIIE, Osamu YAJIMA, Mikihiko TANGO, Masumi TOMIZAWA, Yoshio KURIHARA, Yomei HIRAGA, Kohki KIKUCHI, Asako YAMAMOTO, Masao TAMURA, Takashi ITO, Shinya MIYAMOTO, Kiyoshi KONNO, Kotaro OIZUMI, Seiichi AONUMA, Kosaku NAGAI, Izumi HAYASHI, Tsugushi ITO, Masataka KATSU, Kenichi OKAYAMA, Masaaki ARAKAWA, Hajime TAKEDA, Koichi WADA, Osamu SEKINE, Nobuki AOKI, Yoshimaru USUDA, Fusanosuke YAMASAKU, Yasutoshi SUZUKI, Yutaka KANAZAWA, Tadashi MIYAHARA, Atsushi SAITO, Kohya SHIBA, Hideo IKEMOTO, Kazuyoshi WATANABE, Kentaro WATANABE, Masaru KOYAMA, Katsuhito ITO, Fukuo IIJIMA, Keimei MASHIMO, Tetsuro UKAI, Hiroichi TANIMOTO, Tatsuo NAKATANI, Kunihiko YOSHIMURA, Yoshitaka NAKAMORI, Naohiko CHONABAYASHI, Koichiro NAKATA, Junzaburo KABE, Hiroyoshi ISHIBASHI, Yasuyuki SANO, Ryozo YONEDA, Atsuyuki KURASHIMA, Ippei FUJIMORI, Yoshio KOBAYASHI, Yasushi NAKAMURA, Kazufuto FUKAYA, Tadashi TAKIGAMI, Shigeki ODAGIRI, Kaneo SUZUKI, Kou MUROHASHI, Shinichiro WATANABE, Masanori MATSUMURA, Keinosuke NOSE, Kaoru OYAMA, Nobuo OHYA, Mitsuru HAYASE, Toshihiko TAKEUCHI, Toshiyuki YAMAMOTO, Masahito KATO, Joichi KATO, Hidekazu HANAKI, Ikuji USAMI, Fumiyuki KUZE, Michiyasu NAKANISHI, Hideki NISHIYAMA, Hiroyuki TSUJINO, Nobuo INABA, Akira KAGIOKA, Takekuni IWATA, Kazukiyo OIDA, Tsuneo MATSUBARA, Kohei AOKI, Hiroshi OKUBO, Yoshihiro UEDA, Keigo MAEHARA, Yube IIDA, Seibun YONEZU, Yuruko OKAMOTO, Kojiro YASUNAGA, Fumio MIKI, Yoshiyasu IKUNO, Eiji INOUE, Minoru YOSHIYAMA, Susumu HIRAGA, Tetsuto MURATA, Shinichi TANIZAWA, Kazuo SAKAMOTO, Kazunori KOZUMI, Kenji TAKAMATSU, Riichiro MIKAMI, Masayoshi SAWAKI, Rinzo SOEJIMA, Yoshihito NIKI, Masatoshi WATANABE, Osamu KURIMURA, Hideo SASAKI, Hirofumi FUKUHARA, Masakazu TAMURA, Yoshiro SAWAE, Kaoru OKADA, Minoru YOSHIDA, Masahide TAKII, Masahiko SEKI, Hitoshi NAGANO, Ryuji HIROSE, Atsushi SHINODA, Tsuneo ISHIBASHI, Masahiro TAKAMOTO, Kohei HARA, Kinichi IZUMIKAWA, Keizo YAMAGUCHI, Yoji SUZUYAMA, Yoshiteru SHIGENO, Akira IKEBE, Toshiro ODA, Michisuke OHTA, Keizo MATSUMOTO, Mikio TAGUCHI, Tsuyoshi NAGATAKE, Takashi ITOGA, Masaru NASU, Jun GOTO, Yoichiro GOTO, Takayoshi TASHIRO, Yasuyuki HAYASHI, and Toyoko OGURI

Subjects
Adult, Male, medicine.medical_specialty, Penicillin Resistance, Sultamicillin, Penicillanic Acid, Gastroenterology, Double-Blind Method, Ampicillin, Internal medicine, medicine, Humans, Respiratory Tract Infections, Aged, Clinical Trials as Topic, Respiratory tract infections, business.industry, Pneumonia, General Medicine, Sulbactam, Middle Aged, medicine.disease, Drug Combinations, Penicillin resistance, Bacampicillin, Drug Evaluation, Female, business, medicine.drug
Published
1985
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8. Comparative study of specific activity of [11C]methyl iodide: A search for the source of carrier carbon

Author

Akira Ujiie, Toshihiro Takahashi, Kiichi Ishiwata, Makoto Sugahara, Tatsuo Ido, Kentaro Hatano, and Ren Iwata

Subjects
chemistry.chemical_classification, General Engineering, chemistry.chemical_element, Alcohol, High-performance liquid chromatography, chemistry.chemical_compound, chemistry, Isotopes of carbon, Heterocyclic compound, Carbon dioxide, Organic chemistry, Gas chromatography, Carbon, Methyl iodide, Nuclear chemistry
Abstract

Any no-carrier-added 11 C-compounds prepared from [ 11 C]CH 3 I seem to coexist with at least about 0.2 μmol of its non-radioactive form (carrier). In order to elucidate the source of the carrier, 11 C]CH 3 I prepared under various conditions was converted into several 11 C-compounds and their specific activities were measured by high performance liquid chromatography. Carbon contamination of LiAlH 4 was also examined by gas chromatography. It was shown that only a negligible amount of CO 2 was brought with the irradiated target N 2 gas and that the carrier amount decreased remarkably with the reduction of the amount and concentration of the LiAlH 4 THF solution but not to less than 0.2 μmol. The use of Et 2 O or Pr 2 O instead of THF was found to give EtOH or PrOH, respectively, together with MeOH, all in small amounts. Hence, the 0.2 μmol carrier can be regarded as being originated in MeOH formed from a trace of THF remaining in the LiALH 4 after its drying step.

Published
1988
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9. [18F]fluoride production with a circulating [18O]water target

Author

Akira Ujiie, Ren Iwata, Tatsuo Ido, Frank Brady, and Toshihiro Takahashi

Subjects
chemistry.chemical_compound, chemistry, Yield (chemistry), Radiochemistry, General Engineering, Irradiation, Irradiation time, 18f fluoride, Fluoride, Beam (structure), Catalysis, Volumetric flow rate
Abstract

[18F]fluoride was produced via the 18O(p,n)18F reaction with a circulating 20% enriched [18O]water target. Parameters affecting the production yield of [18F]fluoride such as beam current, beam profile, irradiation time, target thickness, circulation rate, and window material were investigated and optimized. With a 20 μA irradiation of 2.5 mL [18O]water circulated at a flow rate of over 35 mL/min, a [18F]fluoride yield of more than 70% was obtained when the beam was defocussed and wobbled to get a uniform beam profile. In addition, radiolytically produced gases were recombined using a Pd catalyst into the target.

Published
1987
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10. Comparative Study of the Effectiveness of Cefotaxime and Cefazolin on Respiratory Tract Infection

Author

Tadashi Miyazawa, Yoshihiro Ueda, Toshio Fujioka, Seiichi Honma, Kaoru Oyama, Yasutoshi Suzuki, Takehito Nakamura, Shiro Kosaka, Tsukasa Yoshida, Mitsunobu Akashi, Takashi Watanabe, Tadashi Miyahara, Ryoji Ohashi, Tamotsu Takishima, Akio Aoyagi, Fumio Miki, Kohei Hara, Shinichi Morinaga, Koya Shiba, Morikuni Abe, Gen Tajima, Okui S, Fumio Nagahama, Yasutsugu Fukuda, Kosuke Nakazawa, Takamitsu Kido, Shuichiro Yoshida, Susumu Suetsugu, Kuninori Suzuki, Kazuki Miura, Makoto Imaoka, Teruo Katayama, Keiko Cho, Masahito Okayasu, Takashi Ito, Toshio Hojyo, Michiyasu Nakanishi, Mitsuo Nakamura, Masumi Tomizawa, Kotaro Oizumi, Hironobu Ihara, Ryutaro Kiuchi, Nobuki Aoki, Kiyoshi Konno, Yoichiro Ichikawa, Masanaga Takato, Jingoro Shimada, Tsuneo Tsutsumi, Yoshito Niki, Ryuzo Fueki, Koichi Watanabe, Masayuki Ando, Takehumi Kunieda, Kenji Kubo, Keisuke Nishiwaki, Yoshio Kobayashi, Yasuo Nomura, Ko Fujii, Takekuni Iwata, Masatoshi Ide, Harumi Shishido, Nobuharu Oe, Yoshio Hoshihara, Sumio Yamaoka, Yoji Suzuyama, Takehisa Yamaji, Kazuhiko Hagane, Kazuo Sasaki, Koichiro Nakada, Shuzo Sakai, Katsuhiro Okamoto, Hiromi Asakura, Yoshioki Niwa, Toshiyuki Yamamoto, Mitsuru Iwakura, Kazue Sadamoto, Rinzo Soejima, Kosho Yoshikawa, Keiichi Nakagawa, Tatsuo Suzuki, Yukio Nishimoto, Kunio Kudo, Yoshihiro Kumasaka, Yoshio Kinoshita, Masataka Katsu, Tadashi Takigami, Yoshimaru Usuda, Hiroshi Okubo, Hisao Kimura, Kaoru Okada, Shinichi Matsuo, Hiroichi Tanimoto, Akira Saito, Osamu Sekine, Ippei Fujimori, Kaoru Shimada, Akio Tachibana, Katsuhiko Matsui, Yomei Hiraga, Hisashi Nakahata, Izumi Hayashi, Yoshiteru Shigeno, Noboru Shimizu, Masahisa Omori, Kenichi Kimura, Hiromi Kato, Atsushi Saito, Yoshihiko Matsuda, Rokushi Oka, Michio Yamakido, Masahito Kato, Eiro Tsubura, Otohiko Kunii, Shigeru Miyano, Akira Ujiie, Atsushi Shimomura, Hiroshi Nagano, Toshiro Oda, Jutaro Shimomura, Kazuo Horie, Haruhiko Tokuomi, Shoko Narita, Kazuo Takebe, Keiji Takahashi, Mitsuko Takamura, Kazufuto Fukaya, Ken-ichi Imamura, Masao Nakatomi, Keigo Maehara, Masaru Nasu, Toshiyuki Maeda, Katsumasa Tokunaga, Yasuo Matsuoka, Shoji Yasui, Tsuneo Matsubara, Ryokichi Takasugi, Hajimu Takeda, Kenzo Shiota, Takafumi Yano, Kiyoya Izumi, Shigeru Nagaoka, Genichi Tanaka, Hiroshi Okano, Tetsuaki Inokuchi, Kozo Mori, Yasushi Yamada, Seiichi Murakami, Osamu Kitamoto, Makoto Fukui, Shinya Yasuda, Yasumichi Kato, Hideo Ikemoto, Fumihiko Uba, Mitsuaki Yoshioka, Yasuhiro Kawabe, Hirohiko Nagasaka, Hiromichi Umeda, Hiroyuki Kobayashi, Keizo Matsumoto, Nobuaki Tsuzuki, Yoshiro Sawae, Takeshi Mashima, Toshikatsu Kato, Tomohiro Kanazawa, Sumio Arai, Kiyohito Takahashi, Kiyofumi Ishikawa, Junzaburo Kabe, Keimei Mashimo, Setsuo Kobayashi, Norio Kihara, Toshihiko Yoshiga, Shigechika Kado, Hideo Sasaki, Fusanosuke Yamasaku, Kazuhiko Ito, Mikihiko Kudo, Saburo Yano, Yuruko Okamoto, Tsunetoshi Koteda, Nobuo Maekawa, Masanori Morise, Masaro Kaji, Kazuyoshi Watanabe, Yoshihiro Takishita, Masanori Adachi, Yoshihiko Tano, Yasuko Yuasa, Kinichi Izumikawa, Hideyo Noguchi, and Osamu Kurimura

Subjects
medicine.anatomical_structure, Cefotaxime, business.industry, Anesthesia, Cefazolin, medicine, General Medicine, business, medicine.drug, Respiratory tract
Published
1980
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11. Comparative Clinical Study of Cefpiramide (SM-1652) and Cefmetazole for Respiratory Tract Infections by a Double-Blind Method

Author

Hiroyuki KOBAYASHI, Osamu KITAMOTO, Akira SAITO, Yasumichi KATO, Masumi TOMIZAWA, Ichiro NAKAYAMA, Morikuni ABE, Akira UJIIE, Yoshio KINOSHITA, Osamu YAJIMA, Fumio NAGAHAMA, Yuichi SASAKI, Shinya YASUDA, Takehito NAKABAYASHI, Takahisa SAITO, Satoshi YAGUCHI, Kazuo SAOTOME, Yuji IKEDA, Jutaro SHIMOMURA, Mitsuharu OGI, Hiroshi TAKAGI, Akihiko KUZE, Osamu MITSUHASHI, Takashi TAKABORI, Yomei HIRAGA, Kohki KIKUCHI, Hiroshi KAWAI, Kazuo TAKEBE, Kenichi IMAMURA, Yoshihiro KUMASAKA, Kiyohito TAKAHASHI, Hisashi NAKAHATA, Mitsuo NAKAMURA, Takashi CHINOI, Katsuhiro OKAMOTO, Shuichiro YOSHIDA, Naoyoshi MASAKI, Toyokazu TAMURA, Tadashi MIYAZAWA, Hazime WATANABE, Shiro KOSAKA, Makoto NAKAZONO, Tsuneharu BABA, Kazuo SASAKI, Morio SAGARA, Hitoshi YASHIRO, Osamu UEHARA, Masao TAMURA, Ryuji ITO, Taro CHIBA, Kazuki KONISHI, Toshimi SUZUKI, Yoshiaki TAKEZAWA, Yasuo ONO, Hisao KIMURA, Tamotsu TAKISHIMA, Kiyoshi KONNO, Kotaro OIZUMI, Akira WATANABE, Seiichi AONUMA, Kikuo ONUMA, Izumi HAYASHI, Tatsuya ABE, Masataka KATSU, Kenichi OKAYAMA, Kunio IMATAKA, Masanori ADACHI, Fuyuhiko HIGASHI, Hideo IKEMOTO, Kazuyoshi WATANABE, Junko HIBINO, Yasushi UEDA, Atsushi SAITO, Masanobu KAJI, Tadashi MIYAHARA, Ryozo YONEDA, Mitsuo KAWAMURA, Sumio YAMAOKA, Keimei MASHIMO, Keiichi NAKAGAWA, Masaru KOYAMA, Kentaro WATANABE, Motoichi TANAKA, Shinichi ODAMA, Junzaburo KABE, Hiroyoshi ISHIBASHI, Hiroichi TANIMOTO, Akio TACHIBANA, Ippei FUJIMORI, Michinori KOHNO, Yoshio KOBAYASHI, Toshio FUKUI, Kenji MITSUI, Kokichi FUKUSHIMA, Akira ITHO, Kunihiko SHINDO, Shigeki ODAGIRI, Makio KURIHARA, Hideyuki HASEGAWA, Kazufuto FUKAYA, Hajimu TAKEDA, Osamu SEKINE, Yoshimaru USUDA, Nobuki AOKI, Fusanosuke YAMASAKU, Yasutoshi SUZUKI, Kaoru OHYAMA, Kuniyoshi SUZUKI, Ryusaku SHIMIZU, Toshiyuki YAMAMOTO, Saburo KITAURA, Masahito KATO, Kenzo SUZUKI, Kazuo YOSHITOMO, Motoko YAMAMOTO, Akihiko KISHIMOTO, Nobuo MAEKAWA, Michiyasu NAKANISHI, Takekuni IWATA, Mitsuo HASE, Ryoichi AMIYA, Yoichi OSADA, Hiroshi OKUBO, Yuruko OKAMOTO, Yoshihiro UEDA, Keigo MAEHARA, Fumio MIKI, Rinzo SOEJIMA, Yoshito NIKI, Masayasu KAWANISHI, Chikara NAKAHAMA, Yukio NISHIMOTO, Michio YAMAKIDO, Fumiaki TSUKIYAMA, Osamu KURIMURA, Hideo SASAKI, Yoshihiko ARAYA, Yoko KAGAWA, Eiro TSUBURA, Toshihiro GOTO, Yoshihiro TAKISHITA, Yoshiro SAWAE, Kaoru OKADA, Nobuaki SHIGEMATSU, Osamu OGUSHI, Kohei HARA, Tsuneo TSUTSUMI, Kazuhiro OKUNO, Rokushi OKA, Keizo YAMAGUCHI, Youji SUZUYAMA, Toshiyuki OE, Yoshiteru SHIGENO, Naomi ITOH, Hikaru TANAKA, Masao SAI, Keizo MATSUMOTO, Harumi SHISHIDO, Tsuneo ISHIBASHI, Masahiro TAKAMOTO, Atsushi SHINODA, Hitoshi NAGANO, Toshiyuki HAYASHI, Haruhiko TOKUOMI, Yasutsugu FUKUDA, and Katsumasa TOKUNAGA

Subjects
Double blind, Clinical study, medicine.medical_specialty, Respiratory tract infections, business.industry, Internal medicine, medicine, General Medicine, Cefpiramide, Cefmetazole, business, Gastroenterology, medicine.drug
Published
1983
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13. Studies on the Syntheses of Heterocyclic Compounds. DXVI. Total Syntheses of the Aporphine, Morphinandienone, and Tetrahydrodibenzopyrrocoline Alkaloids by Benzyne Reaction

Author

Keiichiro Fukumoto, Toshio Suzuki, Tetsuji Kametani, T. Nakano, Kimio Takahashi, and Akira Ujiie

Subjects
chemistry.chemical_compound, chemistry, Morphinandienone, Sodium amide, Drug Discovery, Liquid ammonia, Organic chemistry, General Chemistry, General Medicine, Domesticine, Aporphine, Thaliporphine, Aryne
Abstract

Benzyne reaction of 1-(2-bromo-4, 5-methylenedioxybenzyl)-1, 2, 3, 4-tetrahydro-7-hydroxy-6-methoxy-2-methylisoquinoline (III) with sodium amide in liquid ammonia gave domesticine (II), amurine (X), and cryptowoline (XI) in one-step. The same reaction of the phenolic bromoisoquinoline (VI) gave thaliporphine (XV) O-methylflavinantine (XVI), and cryptaustoline (I).

Published
1973
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15. Various Welding Problems in the Fabrication of High Pressure Boiler

Author

Akira Ujiie

Subjects
Plastic welding, Engineering, business.industry, Butt welding, Metallurgy, General Engineering, Mechanical engineering, Electrogas welding, Welding, Electric resistance welding, law.invention, Explosion welding, law, Welding power supply, Friction welding, business
Abstract

Various welding problems in the fabrication of high pressure boiler are divided into five groups and discussed as follows : Materials ; Author discusses how to weld heavy wall low alloy steel main steam pipes in the field and also introduces the difficulties encountered with the austenitic piping in the operation and the results of laboratory welding tests conducted with the austenitic piping from the literatures. Welding Machine ; Author discusses various types of welding machines which are applicable for the drums, pipes and tubes. Inspection of welded joints ; Author shows various methods of non-destructive inspection and their typical applications. Heat treatment ; Author made his own experiment to determine the holding time for post heating and the method to interrupt the heat cycle of heavy wall pipe welding. Root pass welding ; Author shows how to use EB insert ring, kellog's method and GE method for the root pass welding without backing ring.

Published
1959
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19. Characteristics of specific in vivo labeling of neuroleptic binding sites with 3-N-[11C]methylspiperone

Author

Taiju Matsuzawa, Toshihiro Takahashi, Kiichi Ishiwata, Tatsuo Ido, Kazuhiko Yanai, Masatoshi Ito, Jun Hatazawa, Shoichi Watanuki, and Akira Ujiie

Subjects
Male, medicine.medical_specialty, Cerebellum, Spiperone, Striatum, Receptors, Dopamine, White matter, Dogs, In vivo, Internal medicine, medicine, Animals, Tissue Distribution, Radiology, Nuclear Medicine and imaging, Carbon Radioisotopes, Binding site, Receptor, Binding Sites, business.industry, Chemistry, Brain, Rats, Inbred Strains, General Medicine, Butyrophenones, Rats, Endocrinology, medicine.anatomical_structure, nervous system, Forebrain, Nuclear medicine, business, Tomography, Emission-Computed, medicine.drug
Abstract

In vivo binding of 3-N-[11C]methylspiperone ([11C]NMSP) was saturable in the rat forebrain, but not in the cerebellum. Nonspecific binding was almost equivalent in all brain regions except for the white matter. [11C]NMSP binding was localized to receptor-rich fractions when low doses were administered (less than 20 nmol/kg body weight). The striatum-to-cerebellum ratio was a function of time after injection and administered dose. This ratio remained constant in low doses of under 30 nmol/kg. The radioactivity curve of the cerebellum in a control positron-emission tomographic study almost equaled that of the striatum in the dog pretreated with spiperone (2 mg). This indicates that the amount of binding in the cerebellum might be considered a nonspecific binding and unbound pool. The data obtained by the pretreatment study was different from that of displacement, which suggested that displaceable [11C]NMSP in the specific binding sites of the striatum was not completely cleared from the brain tissue by a large amount of unlabeled spiperone.

Published
1986
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21. ChemInform Abstract: ALKALOIDS OF FORMOSAN CORYDALIS SPECIES. VI. ELUCIDATION OF THE STRUCTURES OF F TWO SPIROBENZYLISOQUINOLINE ALKALOIDS, YENHUSOMINE AND YENHUSOMIDINE, AND TWO BERBINE ALKALOIDS, CORYTENCHINE AND CORYTENCHIRINE, FROM CORYDALIS OCHOTENSI

Author

Masataka Ihara, Akira Ujiie, Keiichiro Fukumoto, Sheng-Teh Lu, Tsann-Long Su, and Tetsuji Kametani

Subjects
biology, Chemistry, Stereochemistry, Corytenchine, General Medicine, Corydalis, biology.organism_classification
Published
1976
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22. [Comparative clinical trial of HBK and amikacin (AMK) in the treatment of respiratory infections]

Author

Kohei HARA, Atsushi SAITO, Keizo YAMAGUCHI, Yoshiteru SHIGENO, Kazushige TAIRA, Toshiro ODA, Toshiaki HAYASHI, Hiroshi TOMITA, Yasuharu MASUYAMA, Akira SAITO, Masumi TOMIZAWA, Ichiro NAKAYAMA, Morikuni ABE, Shosei MATSUHASHI, Kiyofumi ISHIKAWA, Akira UJIIE, Takehito NAKABAYASHI, Tetsuji KOROKU, Yohmei HIRAGA, Kohki KIKUCHI, Asako YAMAMOTO, Kazuo TAKEBE, Katsuhiro OKAMOTO, Morio SAGARA, Toyokazu TAMURA, Katsumi ENDO, Tatsuro IRIE, Osamu UEHARA, Masao TAMURA, Takashi ITO, Kazuo OBARA, Shinya MIYAMOTO, Tomohiro KANAZAWA, Hiroshi TAKAHASHI, Hirokazu KUROKAWA, Shoji YASUI, Keiji TAKAHASHI, Shinobu SATO, Hideki IKEDA, Hidenori NAKAMURA, Seiji YASUMURA, Kohichi IGARASHI, Hikaru HOSHI, Sunao YAKUWA, Tamotsu TAKISHIMA, Shiroh IDA, Kiyoshi KONNO, Kotaro OIZUMI, Seiichi AONUMA, Akira WATANABE, Kosaku NAGAI, Kazuo SATO, Izumi HAYASHI, Masataka KATSU, Mieko KAWAI, Koji OGIWARA, Takeshi KAWAI, Atsushi AJISAWA, Shigeaki SATO, Kazuhito ISHIKAWA, Tadashi MIYAHARA, Hideo IKEMOTO, Kazuyoshi WATANABE, Hiroshi ISONUMA, Hiroyuki KOBAYASHI, Shin KAWAI, Masahiko YOSHIDA, Otohiko KUNII, Keimei MASHIMO, Yoshiji YAMANE, Tetsuro UKAI, Masaru KOYAMA, Fukuo IIJIMA, Junzaburo KABE, Hiroyoshi ISHIBASHI, Yuko UNO, Hiroichi TANIMOTO, Naohiko CHONABAYASHI, Yoshitaka NAKAMORI, Kunihiko YOSHIMURA, Tatsuo NAKATANI, Koichiro NAKATA, Gohta MASUDA, Masayoshi NEGISHI, Chenden YOUNG, Fuyuhiko HIGASHI, Yuzo FUNATSU, Ippei FUJIMORI, Yoshio KOBAYASHI, Takao OKUBO, Akira ITO, Fumihiko SANO, Michio MATSUZAKI, Yuko ASADA, Shigeki ODAGIRI, Kaneo SUZUKI, Kou MUROHASHI, Tsutomu FUKUDA, Yasuhiro YOSHIIKE, Masanori MATSUMURA, Mitsuyo KIUCHI, Fumio MATSUMOTO, Kazufuto FUKAYA, Tadashi TAKIGAMI, Masataka SHODA, Masaaki ARAKAWA, Kohichi WADA, Osamu SEKINE, Nobuki AOKI, Kaoru OYAMA, Shinobu NAKAMURA, Takeshi NAKAMURA, Toshiyuki YAMAMOTO, Kanzo SUZUKI, Akira ADACHI, Fumiyuki KUZE, Michiyasu NAKANISHI, Takuya KURASAWA, Yoshiro KUBO, Hideki NISHIYAMA, Nobuaki IKEDA, Norio INABA, Akira KAGIOKA, Fumio MIKI, Yoshiyasu IKUNO, Eiji INOUE, Akihito MURATA, Shin-ichi TANIZAWA, Kazuo SAKAMOTO, Kenji TAKAMATSU, Rinzo SOEJIMA, Yoshihito NIKI, Jiro HINO, Yoshihisa NAKAGAWA, Yukio NISHIMOTO, Michio YAMAKIDO, Akimitsu KAMITSUNA, Kenji HASEGAWA, Osamu KURIMURA, Hideo SASAKI, Hirofumi FUKUHARA, Masakazu TAMURA, Eiro TSUBURA, Koichi FUKUYAMA, Tadaaki MORIMOTO, Yoshiro SAWAE, Hitoshi NAGANO, Takeo YOKOTA, Kinji YOKOTA, Atsushi SHINODA, Tsuneo ISHIBASHI, Masahiro TAKAMOTO, Yasuko HARADA, Yoshinari KITAHARA, Masaro KAJI, Yoichiro ICHIKAWA, Masaru NASU, Jun GOTO, Yoichiro GOTO, Hitoshi YAMAZAKI, Takayoshi TASHIRO, Keizo MATSUMOTO, Kazunori OHISHI, Kinichi IZUMIKAWA, Tsunetoshi KOTEDA, Manabu NAKAJIMA, Kohei KOMATSU, Masaya NAKATA, Reiko SENJU, Masayuki ANDO, Moritaka SUGA, Toshifumi NIIBORI, Toshiyuki NAKAGAWA, Kazuko YOSHIDA, Kazumine KOBARI, Masao NAKATOMI, and Tsuneo TANAKA

Subjects
Adult, Male, medicine.medical_specialty, Double-Blind Method, Kanamycin, medicine, Humans, Respiratory system, Intensive care medicine, Amikacin, Respiratory Tract Infections, Aged, Aged, 80 and over, Clinical Trials as Topic, business.industry, Dibekacin, General Medicine, Bacterial Infections, Middle Aged, Anti-Bacterial Agents, Clinical trial, Aminoglycosides, Female, business, medicine.drug
Published
1987

27. [A double-blind comparative study of aspoxicillin and piperacillin in the treatment of respiratory tract infections]

Author

Akira SAITO, Kiyofumi ISHIKAWA, Ichiro NAKAYAMA, Masumi TOMIZAWA, Morikuni ABE, Hidetoshi SHIBAKI, Takehisa CHIMOTO, Masahiro TANAKA, Choei ITO, Keisuke TAKEUCHI, Aiji KOJIMA, Kazuo SHIMOYAMA, Yoshinobu TAKASHIRO, Shinji OHNISHI, Masahide SHINOHARA, Akira UJIIE, Osamu YAJIMA, Fumio NAGAHAMA, Hisaji NISHIHARA, Yuichi SASAKI, Takehito NAKABAYASHI, Tetsuji KOROKU, Rensuke KURODA, Jutaro SHIMOMURA, Shin-ichi OSHIMA, Sokichi ONODERA, Nobuhiro SASAKI, Akira SUZUKI, Tohru NATSUIZAKA, Yohmei HIRAGA, Kohki KIKUCHI, Asako YAMAMOTO, Tsuyoshi KIKUIRI, Tadashi MURAKAMI, Kazufumi TSUCHIHASHI, Kazuo TAKEBE, Katsuhiro OKAMOTO, Shuichiro TOSHIDA, Tadanao OHMI, Shuichi TAKAHASHI, Katsutoshi KARIYA, Tomio ONUMA, Shigeru OCHIAI, Yoshihiro KUMASAKA, Shigetoshi YANAGIYA, Osamu UEHARA, Yasukimi WATABIKI, Naoyoshi MASAKI, Toyoichi TAMURA, Naoki TAMAZAWA, Hajime INOOKA, Masao TAMURA, Takashi ITOH, Ken-ichi TAKEUCHI, Ryoji OGATA, Jun KOMURO, Hiroaki ITOH, Tamotsu TAKISHIMA, Yasuo TANNO, Kiyoshi KONNO, Kotaro OHIZUMI, Akira WATANABE, Makoto KASHIWAGI, Hideo TOGASHI, Hidetaka SATO, Masato HAYASHI, Tsugushi ITOH, Izumi HAYASHI, Osamu SEKINE, Yoshimaru USUDA, Nobuki AOKI, Fusanosuke YAMASAKU, Yasutoshi SUZUKI, Masataka KATSU, Masanori ADACHI, Keimei MASHIMO, Tetsuro UKAI, Chizuru ITOH, Atsushi SAITO, Tadashi MIYAHARA, Hiroichi TANIMOTO, Akio TACHIBANA, Yoshitaka NAKAMORI, Naohiko CHONABAYASHI, Kunihiko YOSHIMURA, Junzaburo KABE, Hiroyoshi ISHIBASHI, Hideo IKEMOTO, Kazuyoshi WATANABE, Keiichi NAKAGAWA, Masaru KOYAMA, Kohjin KIN, Masami UEDA, Fukuo IIJIMA, Ryuji AKIYOSHI, Yuzo FUNATSU, Fuyuhiko HIGASHI, Hiroyuki KOBAYASHI, Hiroshi OSHITANI, Ippei FUJIMORI, Yoshio KOBAYASHI, Yasushi NAKAMURA, Kazufuto FUKAYA, Kenzo TAKAGI, Ikuo YAMAKAWA, Michihiro HARA, Tatsuo SATAKE, Toshihiko TAKEUCHI, Masahito KATO, Saburo KITAURA, Hidekazu HANAKI, Toshiyuki YAMAMOTO, Kanzo SUZUKI, Akihiko KISHIMOTO, Youichi ABE, Katsutaka TORIGAI, Kaoru OHYAMA, Kuninori SUZUKI, Nobuo OHYA, Mitsuru HAYASE, Nobuo MAEKAWA, Michiyasu NAKANISHI, Kohei AOKI, Tsuneo MATSUBARA, Nobuaki IKEDA, Takekuni IWATA, Nobuo INABA, Hiroyuki TSUJINO, Yuruko OKAMOTO, Keigo MAEHARA, Muneto YOSHIOKA, Yube IIDA, Hiroshi OKUBO, Yoshihiro UEDA, Fumio MIKI, Kenji TAKAMATSU, Osamu MIYAMOTO, Eiro TSUBURA, Toshihiro GOTO, Masakazu TAMURA, Rinzo SOEJIMA, Yoshito NIKI, Masatoshi WATANABE, Michio YAMAKIDO, Kanoko HAYASHI, Yoshiro SAWAE, Tomohiro KUSABA, Seizaburo KASHIWAGI, Akira UEDA, Kaoru OKADA, Michio ONO, Masahide TAKII, Takatoshi OTONARI, Kohei HARA, Keizo YAMAGUCHI, Yoji SUZUYAMA, Yoshiteru SHIGENO, Koichi WATANABE, Masao NAGASAWA, Keizo MATSUMOTO, Harumi SHISHIDO, Atsushi TAKAHASHI, Masakazu TAKASUGI, Shigeru TAMAKI, Hisao KIMURA, Masayuki ANDO, Mineharu SUGIMOTO, Moritaka SUGA, Katsumasa TOKUNAGA, Yasutsugu FUKUDA, and Haruhiko TOKUOMI

Subjects
Piperacillin, medicine.medical_specialty, Clinical Trials as Topic, Respiratory tract infections, business.industry, Amoxicillin, Lung abscess, General Medicine, Pneumonia, medicine.disease, Double blind, Aspoxicillin, Chronic disease, Double-Blind Method, Internal medicine, Chronic Disease, medicine, Humans, Lung Abscess, business, Respiratory Tract Infections, medicine.drug
Published
1985

34. Studies on the alkaloids of formosan Corydalis species. Part VI. Elucidation of the structures of two spirobenzylisoquinoline alkaloids, yenhusomine and yenhusomidine, and two berbine alkaloids, corytenchine and corytenchirine, from Corydalis ochotensis(turcz.)

Author

Akira Ujiie, Keiichiro Fukumoto, Tsann-Long Su, Sheng-Teh Lu, Masataka Ihara, and Tetsuji Kametani

Subjects
chemistry.chemical_compound, Corydalis ochotensis, biology, Chemistry, Stereochemistry, Corytenchine, Protopine, Corydalis, biology.organism_classification
Abstract

Separation of the basic fraction from Corydalis ochotensis(Turcz.) afforded four new alkaloids [yenhusomine (5), yenhusomidine (9), corytenchine (12), and corytenchirine (21)] together with the known alkaloids, protopine, ochotensimine, and adlumidine. The identification of the new alkaloids is described. Didehydrocheilantifoline was also isolated, from a quaternary base fraction.

Published
1976
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