30 results on '"Akesson, Karin"'
Search Results
2. Factors associated with empowerment after participating in a supported osteoarthritis self-management program: An explorative study
- Author
-
Åkesson, Karin Sturesdotter, Hansson, Eva Ekvall, Pawlikowska, Teresa, Sundén, Anne, Stigmar, Kjerstin, and Ageberg, Eva
- Published
- 2024
- Full Text
- View/download PDF
3. Assisting the implementation of screening for type 1 diabetes by using artificial intelligence on publicly available data
- Author
-
Teixeira, Pedro F., Battelino, Tadej, Carlsson, Anneli, Gudbjornsdottir, Soffia, Hannelius, Ulf, von Herrath, Matthias, Knip, Mikael, Korsgren, Olle, Larsson, Helena Elding, Lindqvist, Anton, Ludvigsson, Johnny, Lundgren, Markus, Nowak, Christoph, Pettersson, Paul, Pociot, Flemming, Sundberg, Frida, Akesson, Karin, Lernmark, Ake, Forsander, Gun, Teixeira, Pedro F., Battelino, Tadej, Carlsson, Anneli, Gudbjornsdottir, Soffia, Hannelius, Ulf, von Herrath, Matthias, Knip, Mikael, Korsgren, Olle, Larsson, Helena Elding, Lindqvist, Anton, Ludvigsson, Johnny, Lundgren, Markus, Nowak, Christoph, Pettersson, Paul, Pociot, Flemming, Sundberg, Frida, Akesson, Karin, Lernmark, Ake, and Forsander, Gun
- Abstract
The type 1 diabetes community is coalescing around the benefits and advantages of early screening for disease risk. To be accepted by healthcare providers, regulatory authorities and payers, screening programmes need to show that the testing variables allow accurate risk prediction and that individualised risk-informed monitoring plans are established, as well as operational feasibility, cost-effectiveness and acceptance at population level. Artificial intelligence (AI) has the potential to contribute to solving these issues, starting with the identification and stratification of at-risk individuals. ASSET (AI for Sustainable Prevention of Autoimmunity in the Society; www.asset.healthcare) is a public/private consortium that was established to contribute to research around screening for type 1 diabetes and particularly to how AI can drive the implementation of a precision medicine approach to disease prevention. ASSET will additionally focus on issues pertaining to operational implementation of screening. The authors of this article, researchers and clinicians active in the field of type 1 diabetes, met in an open forum to independently debate key issues around screening for type 1 diabetes and to advise ASSET. The potential use of AI in the analysis of longitudinal data from observational cohort studies to inform the design of improved, more individualised screening programmes was also discussed. A key issue was whether AI would allow the research community and industry to capitalise on large publicly available data repositories to design screening programmes that allow the early detection of individuals at high risk and enable clinical evaluation of preventive therapies. Overall, AI has the potential to revolutionise type 1 diabetes screening, in particular to help identify individuals who are at increased risk of disease and aid in the design of appropriate follow-up plans. We hope that this initiative will stimulate further research on this very timely topic.
- Published
- 2024
- Full Text
- View/download PDF
4. Teenage girls with type 1 diabetes have poorer metabolic control than boys and face more complications in early adulthood
- Author
-
Samuelsson, Ulf, Anderzén, Johan, Gudbjörnsdottir, Soffia, Steineck, Isabelle, Åkesson, Karin, and Hanberger, Lena
- Published
- 2016
- Full Text
- View/download PDF
5. Teenagers with poor metabolic control already have a higher risk of microvascular complications as young adults
- Author
-
Anderzén, Johan, Samuelsson, Ulf, Gudbjörnsdottir, Soffia, Hanberger, Lena, and Åkesson, Karin
- Published
- 2016
- Full Text
- View/download PDF
6. A collaborative comparison of international pediatric diabetes registries
- Author
-
Lanzinger, Stefanie, Zimmermann, Anthony, Ranjan, Ajenthen G., Gani, Osman, Pons Perez, Saira, Akesson, Karin, Majidi, Shideh, Witsch, Michael, Hofer, Sabine, Johnson, Stephanie, Pilgaard, Kasper A., Kummernes, Siv Janne, Robinson, Holly, Eeg‐Olofsson, Katarina, Ebekozien, Osagie, Holl, Reinhard W., Svensson, Jannet, Skrivarhaug, Torild, Warner, Justin, Craig, Maria E., and Maahs, David
- Subjects
Adult ,Adolescent ,Endocrinology, Diabetes and Metabolism ,Diabetes mellitus Typ 1 ,Kind ,registry ,Netzwerk ,quality improvement ,Benchmarking ,Diabetes mellitus ,Diabetes mellitus, Type 1 ,Pediatrics, Perinatology and Child Health ,diabetes mellitus ,network ,Internal Medicine ,Jugend ,Humans ,Prospective Studies ,ddc:610 ,Registries ,benchmarking ,Child ,DDC 610 / Medicine & health ,Aged - Abstract
Background An estimated 1.1 million children and adolescents aged under 20 years have type 1 diabetes worldwide. Principal investigators from seven well‐established longitudinal pediatric diabetes registries and the SWEET initiative have come together to provide an international collaborative perspective and comparison of the registries. Work Flow Information and data including registry characteristics, pediatric participant clinical characteristics, data availability and data completeness from the Australasian Diabetes Data Network (ADDN), Danish Registry of Childhood and Adolescent Diabetes (DanDiabKids), Diabetes prospective follow‐up registry (DPV), Norwegian Childhood Diabetes Registry (NCDR), National Paediatric Diabetes Audit (NPDA), Swedish Childhood Diabetes Registry (Swediabkids), T1D Exchange Quality Improvement Collaborative (T1DX‐QI), and the SWEET initiative was extracted up until 31 December 2020. Registry Objectives and Outcomes The seven diabetes registries and the SWEET initiative collectively show data of more than 900 centers and around 100,000 pediatric patients, the majority with type 1 diabetes. All share the common objectives of monitoring treatment and longitudinal outcomes, promoting quality improvement and equality in diabetes care and enabling clinical research. All generate regular benchmark reports. Main differences were observed in the definition of the pediatric population, the inclusion of adults, documentation of CGM metrics and collection of raw data files as well as linkage to other data sources. The open benchmarking and access to regularly updated data may prove to be the most important contribution from registries. This study describes aspects of the registries to enable future collaborations and to encourage the development of new registries where they do not exist., publishedVersion
- Published
- 2022
7. 806 - FACTORS ASSOCIATED WITH EMPOWERMENT AFTER PARTICIPATING IN A SUPPORTED OSTEOARTHRITIS SELF-MANAGEMENT PROGRAMME: AN EXPLORATIVE STUDY
- Author
-
Åkesson, Karin Sturesdotter, Hansson, Eva Ekvall, Pawlikowska, Teresa, Sundén, Anne, Stigmar, Kjerstin, and Ageberg, Eva
- Published
- 2024
- Full Text
- View/download PDF
8. Changes in HbA1c Between 2011 and 2017 in Germany/Austria, Sweden, and the United States: A Lifespan Perspective
- Author
-
Albanese-O'Neill, Anastasia, primary, Grimsmann, Julia M., additional, Svensson, Ann-Marie, additional, Miller, Kellee M., additional, Raile, Klemens, additional, Akesson, Karin, additional, Calhoun, Peter, additional, Biesenbach, Beate, additional, Eeg-Olofsson, Katarina, additional, Holl, Reinhard W., additional, Maahs, David M., additional, and Hanas, Ragnar, additional
- Published
- 2022
- Full Text
- View/download PDF
9. Celiac disease can be predicted by high levels of tissue transglutaminase antibodies in children and adolescents with type 1 diabetes
- Author
-
Bybrant, Mara Cerqueiro, Uden, Elin, Frederiksen, Filippa, Gustafsson, Anna L., Arvidsson, Carl-Goran, Fureman, Anna-Lena, Forsander, Gun, Larsson, Helena Elding, Ivarsson, Sten A., Lindgren, Marie, Ludvigsson, Johnny, Marcus, Claude, Lycka, Auste Pundziute, Persson, Martina, Samuelsson, Ulf, Sarnblad, Stefan, Akesson, Karin, Ortqvist, Eva, Carlsson, Annelie, Bybrant, Mara Cerqueiro, Uden, Elin, Frederiksen, Filippa, Gustafsson, Anna L., Arvidsson, Carl-Goran, Fureman, Anna-Lena, Forsander, Gun, Larsson, Helena Elding, Ivarsson, Sten A., Lindgren, Marie, Ludvigsson, Johnny, Marcus, Claude, Lycka, Auste Pundziute, Persson, Martina, Samuelsson, Ulf, Sarnblad, Stefan, Akesson, Karin, Ortqvist, Eva, and Carlsson, Annelie
- Abstract
Objectives Children with type 1 diabetes (T1D) are not included in guidelines regarding diagnosis criteria for celiac disease (CD) without a diagnostic biopsy, due to lack of data. We explored whether tissue transglutaminase antibodies (anti-tTG) that were >= 10 times the upper limit of normal (10x ULN) predicted CD in T1D. Methods Data from the Swedish prospective Better Diabetes Diagnosis study was used, and 2035 children and adolescents with T1D diagnosed between 2005-2010 were included. Of these, 32 had been diagnosed with CD before T1D. The children without CD were repeatedly screened for CD using anti-tTG antibodies of immunoglobulin type A. In addition, their human leukocyte antigen (HLA) were genotyped. All children with positive anti-tTG were advised to undergo biopsy. Biopsies were performed on 119 children and graded using the Marsh-Oberhuber classification. Results All of the 60 children with anti-tTG >= 10x ULN had CD verified by biopsies. The degree of mucosal damage correlated with anti-tTG levels. Among 2003 screened children, 6.9% had positive anti-tTG and 5.6% were confirmed CD. The overall CD prevalence, when including the 32 children with CD before T1D, was 7.0% (145/2035). All but one of the children diagnosed with CD had HLA-DQ2 and/or DQ8. Conclusions As all screened children and adolescents with T1D with tissue transglutaminase antibodies above 10 times the positive value 10x ULN had CD, we propose that the guidelines for diagnosing CD in screened children, when biopsies can be omitted, should also apply to children and adolescents with T1D as a noninvasive method., Funding Agencies|Barndiabetesfonden; Skane County Councils Research and Development Foundation
- Published
- 2021
- Full Text
- View/download PDF
10. International benchmarking in type 1 diabetes:Large difference in childhood HbA1c between eight high-income countries but similar rise during adolescence—A quality registry study
- Author
-
Anderzén, Johan, Hermann, Julia M., Samuelsson, Ulf, Charalampopoulos, Dimitrios, Svensson, Jannet, Skrivarhaug, Torild, Fröhlich-Reiterer, Elke, Maahs, David M., Akesson, Karin, Kapellen, Thomas, Fritsch, Maria, Birkebæk, Niels H., Drivvoll, Ann K., Miller, Kellee, Stephenson, Terence, Hofer, Sabine E., Fredheim, Siri, Kummernes, Siv J., Foster, Nicole, Amin, Rakesh, Hilgard, Dörte, Rami-Merhar, Birgit, Dahl-Jørgensen, Knut, Clements, Mark, Hanas, Ragnar, Holl, Reinhard W., Warner, Justin T., Anderzén, Johan, Hermann, Julia M., Samuelsson, Ulf, Charalampopoulos, Dimitrios, Svensson, Jannet, Skrivarhaug, Torild, Fröhlich-Reiterer, Elke, Maahs, David M., Akesson, Karin, Kapellen, Thomas, Fritsch, Maria, Birkebæk, Niels H., Drivvoll, Ann K., Miller, Kellee, Stephenson, Terence, Hofer, Sabine E., Fredheim, Siri, Kummernes, Siv J., Foster, Nicole, Amin, Rakesh, Hilgard, Dörte, Rami-Merhar, Birgit, Dahl-Jørgensen, Knut, Clements, Mark, Hanas, Ragnar, Holl, Reinhard W., and Warner, Justin T.
- Abstract
Objectives: To identify differences and similarities in HbA1c levels and patterns regarding age and gender in eight high-income countries. Subjects: 66 071 children and adolescents below18 years of age with type 1 diabetes for at least 3 months and at least one HbA1c measurement during the study period. Methods: Pediatric Diabetes Quality Registry data from Austria, Denmark, England, Germany, Norway, Sweden, the United States, and Wales were collected between 2013 and 2014. HbA1c, gender, age, and duration were used in the analysis. Results: Distribution of gender and age groups was similar in the eight participating countries. The mean HbA1c varied from 60 to 73 mmol/mol (7.6%-8.8%) between the countries. The increase in HbA1c between the youngest (0-9 years) to the oldest (15-17 years) age group was close to 8 mmol/mol (0.7%) in all countries (P <.001). Females had a 1 mmol/mol (0.1%) higher mean HbA1c than boys (P <.001) in seven out of eight countries. Conclusions: In spite of large differences in the mean HbA1c between countries, a remarkable similarity in the increase of HbA1c from childhood to adolescence was found.
- Published
- 2020
11. Multiple factors affect the loss of measurable C-peptide over 6 years in newly diagnosed 15- to 35-year-old diabetic subjects
- Author
-
Jensen, Richard A., Gilliam, Lisa K., Törn, Carina, Landin-Olsson, Mona, Karlsson, F. Anders, Palmer, Jerry P., Kockum, Ingrid, Åkesson, Karin, Lernmark, Barbro, Lynch, Kristian, Breslow, Norman, and Lernmark, Åke
- Published
- 2007
- Full Text
- View/download PDF
12. 283-OR: Changes in HbA1c between 2011-2017 in Austria/Germany, Sweden, and the United States: A Lifespan Perspective
- Author
-
ALBANESE-O’NEILL, ANASTASIA, primary, HERMANN, JULIA, additional, SVENSSON, ANN-MARIE, additional, MILLER, KELLEE, additional, RAILE, KLEMENS, additional, AKESSON, KARIN, additional, CALHOUN, PETER, additional, EEG-OLOFSSON, KATARINA, additional, MAAHS, DAVID M., additional, HOLL, REINHARD W., additional, and HANAS, RAGNAR, additional
- Published
- 2020
- Full Text
- View/download PDF
13. 164-LB: Lower Pediatric HbA1c in Sweden during Recent Years Is Associated with a Lower HbA1c Nadir during the First Year after Onset
- Author
-
HANAS, RAGNAR, primary, STEINECK, ISABELLE I., additional, ANDERZÉN, JOHAN, additional, EEG-OLOFSSON, KATARINA, additional, EKELUND, JAN, additional, GUDBJ ÖRNSDOTTIR, SOFFIA, additional, HANBERGER, LENA, additional, NÅTMAN, JONATAN, additional, LYCKÅ, AUSTE PUNDZIUTE, additional, SVENSSON, ANN-MARIE, additional, SÄRNBLAD, STEFAN, additional, and AKESSON, KARIN, additional
- Published
- 2020
- Full Text
- View/download PDF
14. 1314-P: A Low HbA1c during the First 2 Years Correlates with a Higher Percentage of HbA1c ≤6.5% (48 mmol/mol) and Lower Percentage >8.0% (64 mmol/mol) on a Clinic Level
- Author
-
HANAS, RAGNAR, primary, HANBERGER, LENA, additional, LYCKÅ, AUSTE PUNDZIUTE, additional, SAMUELSSON, ULF, additional, SVENSSON, ANN-MARIE, additional, and AKESSON, KARIN, additional
- Published
- 2020
- Full Text
- View/download PDF
15. International benchmarking in type 1 diabetes: Large difference in childhood HbA1c between eight high‐income countries but similar rise during adolescence—A quality registry study
- Author
-
Anderzén, Johan, primary, Hermann, Julia M., additional, Samuelsson, Ulf, additional, Charalampopoulos, Dimitrios, additional, Svensson, Jannet, additional, Skrivarhaug, Torild, additional, Fröhlich‐Reiterer, Elke, additional, Maahs, David M., additional, Akesson, Karin, additional, Kapellen, Thomas, additional, Fritsch, Maria, additional, Birkebæk, Niels H., additional, Drivvoll, Ann K., additional, Miller, Kellee, additional, Stephenson, Terence, additional, Hofer, Sabine E., additional, Fredheim, Siri, additional, Kummernes, Siv J., additional, Foster, Nicole, additional, Amin, Rakesh, additional, Hilgard, Dörte, additional, Rami‐Merhar, Birgit, additional, Dahl‐Jørgensen, Knut, additional, Clements, Mark, additional, Hanas, Ragnar, additional, Holl, Reinhard W., additional, and Warner, Justin T., additional
- Published
- 2020
- Full Text
- View/download PDF
16. Exploring Variation in Glycemic Control Across and Within Eight High-Income Countries:A Cross-sectional Analysis of 64,666 Children and Adolescents With Type 1 Diabetes
- Author
-
Charalampopoulos, Dimitrios, Hermann, Julia M, Svensson, Jannet, Skrivarhaug, Torild, Maahs, David M, Akesson, Karin, Warner, Justin T, Holl, Reinhard W, Birkebæk, Niels H, Drivvoll, Ann K, Miller, Kellee M, Svensson, Ann-Marie, Stephenson, Terence, Hofer, Sabine E, Fredheim, Siri, Kummernes, Siv J, Foster, Nicole, Hanberger, Lena, Amin, Rakesh, Rami-Merhar, Birgit, Johansen, Anders, Dahl-Jørgensen, Knut, Clements, Mark, Hanas, Ragnar, Charalampopoulos, Dimitrios, Hermann, Julia M, Svensson, Jannet, Skrivarhaug, Torild, Maahs, David M, Akesson, Karin, Warner, Justin T, Holl, Reinhard W, Birkebæk, Niels H, Drivvoll, Ann K, Miller, Kellee M, Svensson, Ann-Marie, Stephenson, Terence, Hofer, Sabine E, Fredheim, Siri, Kummernes, Siv J, Foster, Nicole, Hanberger, Lena, Amin, Rakesh, Rami-Merhar, Birgit, Johansen, Anders, Dahl-Jørgensen, Knut, Clements, Mark, and Hanas, Ragnar
- Abstract
OBJECTIVE: International studies on childhood type 1 diabetes (T1D) have focused on whole-country mean HbA1c levels, thereby concealing potential variations within countries. We aimed to explore the variations in HbA1c across and within eight high-income countries to best inform international benchmarking and policy recommendations.RESEARCH DESIGN AND METHODS: Data were collected between 2013 and 2014 from 64,666 children with T1D who were <18 years of age across 528 centers in Germany, Austria, England, Wales, U.S., Sweden, Denmark, and Norway. We used fixed- and random-effects models adjusted for age, sex, diabetes duration, and minority status to describe differences between center means and to calculate the proportion of total variation in HbA1c levels that is attributable to between-center differences (intraclass correlation [ICC]). We also explored the association between within-center variation and children's glycemic control.RESULTS: Sweden had the lowest mean HbA1c (59 mmol/mol [7.6%]) and together with Norway and Denmark showed the lowest between-center variations (ICC ≤4%). Germany and Austria had the next lowest mean HbA1c (61-62 mmol/mol [7.7-7.8%]) but showed the largest center variations (ICC ∼15%). Centers in England, Wales, and the U.S. showed low-to-moderate variation around high mean values. In pooled analysis, differences between counties remained significant after adjustment for children characteristics and center effects (P value <0.001). Across all countries, children attending centers with more variable glycemic results had higher HbA1c levels (5.6 mmol/mol [0.5%] per 5 mmol/mol [0.5%] increase in center SD of HbA1c values of all children attending a specific center).CONCLUSIONS: At similar average levels of HbA1c, countries display different levels of center variation. The distribution of glycemic achievement within countries should be considered in developing informed policies that drive quality improvement.
- Published
- 2018
17. Exploring Variation in Glycemic Control Across and Within Eight High-Income Countries: A Cross-sectional Analysis of 64,666 Children and Adolescents With Type 1 Diabetes
- Author
-
Charalampopoulos, Dimitrios, primary, Hermann, Julia M., additional, Svensson, Jannet, additional, Skrivarhaug, Torild, additional, Maahs, David M., additional, Akesson, Karin, additional, Warner, Justin T., additional, Holl, Reinhard W., additional, Birkebæk, Niels H., additional, Drivvoll, Ann K., additional, Miller, Kellee M., additional, Svensson, Ann-Marie, additional, Stephenson, Terence, additional, Hofer, Sabine E., additional, Fredheim, Siri, additional, Kummernes, Siv J., additional, Foster, Nicole, additional, Hanberger, Lena, additional, Amin, Rakesh, additional, Rami-Merhar, Birgit, additional, Johansen, Anders, additional, Dahl-Jørgensen, Knut, additional, Clements, Mark, additional, and Hanas, Ragnar, additional
- Published
- 2018
- Full Text
- View/download PDF
18. The influence of age, gender, insulin dose, BMI, and blood pressure on metabolic control in young patients with type 1 diabetes
- Author
-
Akesson, Karin, Hanberger, Lena, and Samuelsson, Ulf
- Subjects
children ,gender ,HbA1c ,metabolic control ,quality register ,type 1 diabetes ,Klinisk medicin ,nutritional and metabolic diseases ,Clinical Medicine - Abstract
ObjectiveTo explore the relationship between certain clinical variables and metabolic HbA1c at diagnosis correlated to HbA1c at follow-up (p less than 0.001). There was a clear gender difference regarding HbA1c. Girls had higher values both at diagnosis and at follow-up (p less than 0.001). Girls also had lower BMI and pH at diagnosis than boys (p less than 0.001). In contrast, girls with the highest body mass index (BMI) at follow-up had higher mean HbA1c at follow-up in 2010 (p less than 0.001). Having a mother and/or a father with high BMI implied higher HbA1c at diagnosis (p less than 0.003). ConclusionsHbA1c at diagnosis seems to predict metabolic control years later. There is a gender difference at diagnosis as female patients have higher HbA1c than males at diagnosis as well as at follow up. As metabolic control is very much correlated to complications there is a need to early identify patients at risk of poor metabolic control. Even though we do not know whether a high HbA1c level is mainly due to severity of the disease or to behavioral patterns, new ways to treat and support these children, especially girls, are needed. Funding Agencies|Ostergotland County Council; academy for Health and Care; Jonkoping County Council; Futurum
- Published
- 2015
19. Impact of Type 1 Diabetes on Health-Related Quality of Life Among 8-18-Year-Old Children
- Author
-
Petersson, Christina, Huus, Karina, Enskar, Karin, Hanberger, Lena, Samulesson, Ulf, Akesson, Karin, Petersson, Christina, Huus, Karina, Enskar, Karin, Hanberger, Lena, Samulesson, Ulf, and Akesson, Karin
- Abstract
Measuring the health-related quality of life (HRQOL) is one way to understand an individuals perspective on health, and, more specifically, how type 1 diabetes (T1D) affects a childs everyday life. Early detection of poor HRQOL is considered a crucial factor for identifying children who are at risk of psychosocial problems. The aim of this study was to describe the differences in the HRQOL of children with T1D according to age, gender, and metabolic control (HbA1c). Cross-sectional data were collected from children with T1D using the DISABKIDS Chronic Generic Measure-37 (DCGM-37) and the diabetes specific module (DM-10). Non-parametric tests were used to investigate differences. There were differences between girls and boys, and girls reported lower HRQOL than boys (HRQOL total score: mean 74 and 67 respectively; p = .005). Adolescents described more worries and fears about the future compared with younger children. Children with poor metabolic control reported a lower HRQOL than those with better metabolic control (HRQOL total score: mean 68 and 76 respectively; p = .006), but the social dimensions were not affected. The findings of the present study elucidate the importance for paediatric nurses to explore potential problems in children with T1D and use this knowledge in clinical practice. Assessment of the HRQOL can provide the patients perspective on the quality of diabetes care. The HRQOL is correlated with HbA1c, gender, and age, and the HRQOL as well as HbA1c levels should be regularly assessed to establish a comprehensive care for children with T1D.
- Published
- 2016
- Full Text
- View/download PDF
20. Caesarean section per se does not increase the risk of offspring developing type 1 diabetes: a Swedish population-based study
- Author
-
Samuelsson, Ulf, Lindell, Nina, Bladh, Marie, Akesson, Karin, Carlsson, Annelie, Josefsson, Ann, Samuelsson, Ulf, Lindell, Nina, Bladh, Marie, Akesson, Karin, Carlsson, Annelie, and Josefsson, Ann
- Abstract
Aims/hypothesis Some studies have revealed a relationship between Caesarean section (CS) and type 1 diabetes, while other studies have not. By using the Swedish paediatric quality register we investigated whether birth by CS is related to the risk of developing type 1 diabetes during childhood. Methods All children diagnosed with type 1 diabetes from 2000 to 2012 and included in the register (n= 9,376) were matched with four controls by year, day of birth, sex and county of birth from the Swedish Medical Birth Register. Results Overall, 13.5% of deliveries were by CS. By group, 14.7% of children who developed type 1 diabetes were delivered by CS compared with 13.3% of control children (p less than 0.001). Mothers with diabetes more often gave birth by CS than mothers without diabetes (78.8% vs 12.7%, p less than 0.001). In a logistic regression model adjusting for maternal age, maternal diabetes and BMI in early pregnancy, the OR for CS was 1.0. A child who developed type 1 diabetes and had a mother with type 1 diabetes at the time of delivery had the highest OR to have been born by CS. Children of mothers without diabetes, delivered by CS, had no increased risk of developing type 1 diabetes. Maternal diabetes was the strongest predictor of childhood diabetes (OR 3.4), especially if the mother had type 1 diabetes (OR 7.54). Conclusions/interpretation CS had no influence on the risk of type 1 diabetes during childhood or adolescence. However, maternal diabetes itself strongly increased the risk of offspring developing type 1 diabetes., Funding Agencies|Futurum, the academy for health care, Jonkoping county council
- Published
- 2015
- Full Text
- View/download PDF
21. Use of the national quality registry to monitor health-related quality of life of children with type I diabetes: A pilot study
- Author
-
Petersson, Christina, Huus, Karina, Samuelsson, Ulf, Hanberger, Lena, Akesson, Karin, Petersson, Christina, Huus, Karina, Samuelsson, Ulf, Hanberger, Lena, and Akesson, Karin
- Abstract
The management of diabetes is complicated, as treatment affects the everyday life of both children and their families. To enable optimal care for children with type I diabetes, it is important to highlight health-related quality of life (HrQoL) as well as medical outcomes to detect psychological problems that otherwise could be missed. The aim was to study HrQoL in children and adolescents with type I diabetes dependent on gender, age and co-morbidity and to study the consistency between childrens self-reporting and parents proxy reporting. The cross-sectional data were collected using the questionnaire DISABKIDS Chronic Generic Measure and the DISABKIDS diabetes module. Parents in the proxy report perceived their childrens HrQoL to be lower than children themselves. Boys reported their HrQoL to be better than girls. Results show that living with an additional disease has an impact on the HrQoL, which is an important factor to consider in the quality registry. Assessing HrQoL on a routine basis may facilitate detection and discussion of HrQoL-related questions in the national quality registry.
- Published
- 2015
- Full Text
- View/download PDF
22. Improved Results in Paediatric Diabetes Care Using a Quality Registry in an Improvement Collaborative: A Case Study in Sweden
- Author
-
Peterson, Anette, Hanberger, Lena, Akesson, Karin, Bojestig, Mats, Andersson Gare, Boel, Samuelsson, Ulf, Peterson, Anette, Hanberger, Lena, Akesson, Karin, Bojestig, Mats, Andersson Gare, Boel, and Samuelsson, Ulf
- Abstract
Background: Several studies show that good metabolic control is important for children and adolescents with type 1 diabetes. In Sweden, there are large differences in mean haemoglobin A1c (HbA1c) in different hospitals and difficulties implementing national guidelines in everyday practice. This study shows how the participation in an improvement collaborative could facilitate improvements in the quality of care by paediatric diabetes teams. The Swedish paediatric diabetes quality registry, SWEDIABKIDS was used as a tool and resource for feedback and outcome measures. Methods: Twelve teams at paediatric diabetes centres, caring for 30% (2302/7660) of patients in Sweden, participated in an 18-month quality improvement program. Each team defined treatment targets, areas needing improvement, and action plans. The main outcome was the centre patients mean HbA1c levels, but other clinical variables and change concepts were also studied. Data from the previous six months were compared with the first six months after starting the program, and the long-term follow up after another eleven months. Results: All centres reduced mean HbA1c during the second and third periods compared with the first. The mean reduction for all was 3.7 mmol/mol (pless than0.001), compared with non-participating centres who improved their mean HbA1c with 1.7 mmol/mol during the same period. Many of the participating centres reduced the frequency of severe hypoglycaemia and/or ketoacidosis, and five centres reached their goal of ensuring that all patients had some sort of physical activity at least once weekly. Change concepts were, for example, improved guidelines, appointment planning, informing the patients, improving teamwork and active use of the registry, and health promotion activities. Conclusions: By involving paediatric diabetes teams in a quality improvement collaborative together with access to a quality register, the quality of paediatric diabetes care can improve, thereby contributing t
- Published
- 2014
- Full Text
- View/download PDF
23. Age Dependent Variation of Genotypes in MHCII Transactivator Gene (CIITA) in Controls and Association to Type 1 Diabetes in SCANDINAVIAN JOURNAL OF IMMUNOLOGY, vol 76, issue 2, pp 202-203
- Author
-
Gyllenberg, Alexandra, Asad, Samina, Piehl, Fredrik, Swanberg, Maria, Padyukov, Leonid, Van Yserloo, Brian, A. Rutledge, Elizabeth, McNeney, Brad, Graham, Jinko, Orho-Melander, Marju, Lindholm, Eero, Graff, Caroline, Forsell, Charlotte, Akesson, Karin, Landin-Olsson, Mona, Carlsson, Annelie, Forsander, Gun, A. Ivarsson, Sten, Larsson, Helena, Lindblad, Bengt, Ludvigsson, Johnny, Marcus, Claude, Lernmark, Ake, Alfredsson, Lars, Akesson, Kristina, Olsson, Tomas, Kockum, Ingrid, Gyllenberg, Alexandra, Asad, Samina, Piehl, Fredrik, Swanberg, Maria, Padyukov, Leonid, Van Yserloo, Brian, A. Rutledge, Elizabeth, McNeney, Brad, Graham, Jinko, Orho-Melander, Marju, Lindholm, Eero, Graff, Caroline, Forsell, Charlotte, Akesson, Karin, Landin-Olsson, Mona, Carlsson, Annelie, Forsander, Gun, A. Ivarsson, Sten, Larsson, Helena, Lindblad, Bengt, Ludvigsson, Johnny, Marcus, Claude, Lernmark, Ake, Alfredsson, Lars, Akesson, Kristina, Olsson, Tomas, and Kockum, Ingrid
- Abstract
n/a
- Published
- 2012
24. Use of the national quality registry to monitor health-related quality of life of children with type 1 diabetes
- Author
-
Petersson, Christina, primary, Huus, Karina, additional, Samuelsson, Ulf, additional, Hanberger, Lena, additional, and Akesson, Karin, additional
- Published
- 2013
- Full Text
- View/download PDF
25. Use of the national quality registry to monitor health-related quality of life of children with type 1 diabetes: A pilot study.
- Author
-
Huus, Karina, Hanberger, Lena, Akesson, Karin, Petersson, Christina, and Samuelsson, Ulf
- Abstract
The management of diabetes is complicated, as treatment affects the everyday life of both children and their families. To enable optimal care for children with type 1 diabetes, it is important to highlight health-related quality of life (HrQoL) as well as medical outcomes to detect psychological problems that otherwise could be missed. The aim was to study HrQoL in children and adolescents with type 1 diabetes dependent on gender, age and co-morbidity and to study the consistency between children’s self-reporting and parents’ proxy reporting. The cross-sectional data were collected using the questionnaire DISABKIDS Chronic Generic Measure and the DISABKIDS diabetes module. Parents in the proxy report perceived their children’s HrQoL to be lower than children themselves. Boys reported their HrQoL to be better than girls. Results show that living with an additional disease has an impact on the HrQoL, which is an important factor to consider in the quality registry. Assessing HrQoL on a routine basis may facilitate detection and discussion of HrQoL-related questions in the national quality registry. [ABSTRACT FROM PUBLISHER]
- Published
- 2015
- Full Text
- View/download PDF
26. Age Dependent Variation of Genotypes in MHCII Transactivator Gene (CIITA) in Controls and Association to Type 1 Diabetes
- Author
-
Gyllenberg, Alexandra, Asad, Samina, Piehl, Fredrik, Swanberg, Maria, Padyukov, Leonid, Yserloo, Brian, Rutledge, Elizabeth A., Mcneney, Brad, Graham, Jinko, Orho-Melander, Marju, Lindholm, Eero, Caroline Graff, Forsell, Charlotte, Akesson, Karin, Landin-Olsson, Mona, Carlsson, Annelie, Forsander, Gun, Ivarsson, Sten A., Larsson, Helena, Lindblad, Bengt, Ludvigsson, Johnny, Marcus, Claude, Lernmark, Ake, Alfredsson, Lars, Akesson, Kristina, Olsson, Tomas, and Kockum, Ingrid
27. A collaborative comparison of international pediatric diabetes registries.
- Author
-
Lanzinger S, Zimmermann A, Ranjan AG, Gani O, Pons Perez S, Akesson K, Majidi S, Witsch M, Hofer S, Johnson S, Pilgaard KA, Kummernes SJ, Robinson H, Eeg-Olofsson K, Ebekozien O, Holl RW, Svensson J, Skrivarhaug T, Warner J, Craig ME, and Maahs D
- Subjects
- Adolescent, Adult, Aged, Benchmarking, Child, Humans, Prospective Studies, Quality Improvement, Registries, Diabetes Mellitus, Type 1 epidemiology, Diabetes Mellitus, Type 1 therapy
- Abstract
Background: An estimated 1.1 million children and adolescents aged under 20 years have type 1 diabetes worldwide. Principal investigators from seven well-established longitudinal pediatric diabetes registries and the SWEET initiative have come together to provide an international collaborative perspective and comparison of the registries., Work Flow: Information and data including registry characteristics, pediatric participant clinical characteristics, data availability and data completeness from the Australasian Diabetes Data Network (ADDN), Danish Registry of Childhood and Adolescent Diabetes (DanDiabKids), Diabetes prospective follow-up registry (DPV), Norwegian Childhood Diabetes Registry (NCDR), National Paediatric Diabetes Audit (NPDA), Swedish Childhood Diabetes Registry (Swediabkids), T1D Exchange Quality Improvement Collaborative (T1DX-QI), and the SWEET initiative was extracted up until 31 December 2020., Registry Objectives and Outcomes: The seven diabetes registries and the SWEET initiative collectively show data of more than 900 centers and around 100,000 pediatric patients, the majority with type 1 diabetes. All share the common objectives of monitoring treatment and longitudinal outcomes, promoting quality improvement and equality in diabetes care and enabling clinical research. All generate regular benchmark reports. Main differences were observed in the definition of the pediatric population, the inclusion of adults, documentation of CGM metrics and collection of raw data files as well as linkage to other data sources. The open benchmarking and access to regularly updated data may prove to be the most important contribution from registries. This study describes aspects of the registries to enable future collaborations and to encourage the development of new registries where they do not exist., (© 2022 The Authors. Pediatric Diabetes published by John Wiley & Sons Ltd.)
- Published
- 2022
- Full Text
- View/download PDF
28. Use of the national quality registry to monitor health-related quality of life of children with type 1 diabetes: a pilot study.
- Author
-
Petersson C, Huus K, Samuelsson U, Hanberger L, and Akesson K
- Subjects
- Adolescent, Age Factors, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Infant, Infant, Newborn, Male, Parents, Pilot Projects, Self Report, Surveys and Questionnaires, Young Adult, Diabetes Mellitus, Type 1 psychology, Quality of Life, Registries
- Abstract
The management of diabetes is complicated, as treatment affects the everyday life of both children and their families. To enable optimal care for children with type 1 diabetes, it is important to highlight health-related quality of life (HrQoL) as well as medical outcomes to detect psychological problems that otherwise could be missed. The aim was to study HrQoL in children and adolescents with type 1 diabetes dependent on gender, age and co-morbidity and to study the consistency between children's self-reporting and parents' proxy reporting. The cross-sectional data were collected using the questionnaire DISABKIDS Chronic Generic Measure and the DISABKIDS diabetes module. Parents in the proxy report perceived their children's HrQoL to be lower than children themselves. Boys reported their HrQoL to be better than girls. Results show that living with an additional disease has an impact on the HrQoL, which is an important factor to consider in the quality registry. Assessing HrQoL on a routine basis may facilitate detection and discussion of HrQoL-related questions in the national quality registry., (© The Author(s) 2013.)
- Published
- 2015
- Full Text
- View/download PDF
29. Improved results in paediatric diabetes care using a quality registry in an improvement collaborative: a case study in Sweden.
- Author
-
Peterson A, Hanberger L, Akesson K, Bojestig M, Andersson Gäre B, and Samuelsson U
- Subjects
- Adolescent, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Pediatrics, Registries, Sweden, Cooperative Behavior, Diabetes Mellitus, Type 1 prevention & control, Glycated Hemoglobin analysis, Patient-Centered Care, Quality of Health Care
- Abstract
Background: Several studies show that good metabolic control is important for children and adolescents with type 1 diabetes. In Sweden, there are large differences in mean haemoglobin A1c (HbA1c) in different hospitals and difficulties implementing national guidelines in everyday practice. This study shows how the participation in an improvement collaborative could facilitate improvements in the quality of care by paediatric diabetes teams. The Swedish paediatric diabetes quality registry, SWEDIABKIDS was used as a tool and resource for feedback and outcome measures., Methods: Twelve teams at paediatric diabetes centres, caring for 30% (2302/7660) of patients in Sweden, participated in an 18-month quality improvement program. Each team defined treatment targets, areas needing improvement, and action plans. The main outcome was the centre patients' mean HbA1c levels, but other clinical variables and change concepts were also studied. Data from the previous six months were compared with the first six months after starting the program, and the long-term follow up after another eleven months., Results: All centres reduced mean HbA1c during the second and third periods compared with the first. The mean reduction for all was 3·7 mmol/mol (p<0.001), compared with non-participating centres who improved their mean HbA1c with 1·7 mmol/mol during the same period. Many of the participating centres reduced the frequency of severe hypoglycaemia and/or ketoacidosis, and five centres reached their goal of ensuring that all patients had some sort of physical activity at least once weekly. Change concepts were, for example, improved guidelines, appointment planning, informing the patients, improving teamwork and active use of the registry, and health promotion activities., Conclusions: By involving paediatric diabetes teams in a quality improvement collaborative together with access to a quality register, the quality of paediatric diabetes care can improve, thereby contributing to a reduced risk of late complications for children and adolescents with diabetes.
- Published
- 2014
- Full Text
- View/download PDF
30. Indwelling catheters used from the onset of diabetes decrease injection pain and pre-injection anxiety.
- Author
-
Hanas R, Adolfsson P, Elfvin-Akesson K, Hammarén L, Ilvered R, Jansson I, Johansson C, Kroon M, Lindgren J, Lindh A, Ludvigsson J, Sigström L, Wiik A, and Aman J
- Subjects
- Adolescent, Age of Onset, Analysis of Variance, Anxiety etiology, Child, Child, Preschool, Diabetes Mellitus, Type 1 psychology, Female, Humans, Infant, Injections, Subcutaneous psychology, Male, Pain etiology, Parents psychology, Patient Education as Topic, Time Factors, Anxiety prevention & control, Catheters, Indwelling, Diabetes Mellitus, Type 1 drug therapy, Injections, Subcutaneous adverse effects, Insulin administration & dosage, Pain prevention & control
- Abstract
Objectives: To investigate the use of indwelling catheters as injection aids at diabetes onset to reduce injection pain and pre-injection anxiety., Study Design: Forty-one patients aged 8.1 +/- 3.7 years (range, 1-15) participated in this open, controlled randomized study. A 10-cm VAS with faces was used for scoring. A local anesthetic cream was used before all insertions. The control group used insulin pens with standard needles. After one week, the indwelling catheter group could choose regular injections but were included in the "intention to treat" analysis., Results: Injection pain and anxiety decreased from day 1 to 15 in both groups (average, 4.1 injections/day). Pain was significantly lower for indwelling catheter injections when scored by parents (median, 1.2 cm vs 2.7 cm; P =.002), children/teenagers (0.8 cm vs 1.5 cm; P =.006), and nurses (1.4 cm vs 3.0 cm; P =.002). Parental pre-injection anxiety was also lower (1.2 cm vs 2.9 cm; P =.016). Taking injections, including inserting catheters, was found to be less problematic with an indwelling catheter (1.6 cm vs 3.3 cm;P =.009). During the 6-month follow-up, injection pain and injection problems were significantly lower in the catheter group. Mean catheter indwelling time was 3.7 days. Median pain for catheter insertion was 2.1 cm and for glucose testing was 0.9 cm. Sixteen of 20 patients continued to use indwelling catheters after 2 weeks, and 9 of 20 after 6 months., Conclusions: We found an evident relief of pre-injection anxiety and injection pain when using indwelling catheters for introducing insulin injections at the onset of diabetes.
- Published
- 2002
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.