Search

Your search keyword '"Akentiev, Alexander"' showing total 36 results
Start Over Author "Akentiev, Alexander"
36 results on '"Akentiev, Alexander"'

6. Surface Properties of Aqueous Dispersions of Bovine Serum Albumin Fibrils

Author

Akentiev, Alexander, Lin, Shi-Yow, Loglio, Giuseppe, Miller, Reinhard, Noskov, Boris, Akentiev, Alexander, Lin, Shi-Yow, Loglio, Giuseppe, Miller, Reinhard, and Noskov, Boris

Abstract

The surface properties of aqueous dispersions of worm-like fibril aggregates of bovine serum albumin (BSA) differ from those of the adsorption layers of the native protein. The dispersions of BSA fibrils are characterized by slower changes of the surface tension and dynamic surface elasticity and also have different steady-state values of the surface properties. The fourfold compression of the adsorption layer of BSA fibrils leads to noticeably higher surface pressures than those of a compressed layer of the native protein, indicating the formation of a more rigid layer structure in the former case. The spreading of BSA fibrils onto a liquid surface from a concentrated dispersion reduces the effect of surface-active admixtures on the layer properties. The dependencies of the dynamic surface elasticity on surface pressure almost coincide for the spread layers of fibrils and the native protein in the range of low surface pressures, but only the spreading of the native protein can lead to surface pressures higher than 4 mN/m. This distinction is presumably caused by the formation of stable clusters of BSA fibrils at the interface and their slow propagation along the liquid surface.

Published
2024

7. Silk Fibroin Self-Assembly at the Air–Water Interface.

Author

Milyaeva, Olga Yu., Akentiev, Alexander V., Bykov, Alexey G., Miller, Reinhard, Rafikova, Anastasiya R., Rotanova, Kseniya Yu., and Noskov, Boris A.

Subjects
AIR-water interfaces, SILK fibroin, SURFACE pressure, ATOMIC force microscopy, LIQUID surfaces
Abstract

Amphiphilic silk fibroin (SF) forms stable adsorption layers at the air–water interface. The range of the investigated protein concentrations can be divided into two parts according to the peculiarities of the surface layer properties. At protein concentrations from 0.0005 to 0.01 mg/mL, the dynamic surface elasticity monotonically increases with the concentration and surface age and reaches values of up to 220 mN/m. In this range, the adsorption layer compression leads to a fast increase of the surface pressure. In the second part (>0.01 mg/mL), the surface elasticity decreases again and the kinetic dependences of the film thickness and adsorbed amount change only a little. In this case, the layer compression leads only to a slight increase of the surface pressure. These two types of behavior can be attributed to the distinctions in the protein aggregation in the surface layer. Atomic force microscopy (AFM) investigations of the layers transferred from the liquid surface onto a mica surface by the Langmuir–Schaefer method show some peculiarities of the layer morphology in the intermediate concentration range (~0.02 mg/mL). [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

10. Dendrimer Induced Bilayer Disintegration of Hybrid Vesicles

Author

Guha, Pritam, primary, Roy, Biplab, additional, Nahak, Prasant, additional, Karmakar, Gourab, additional, Karak, Atanu, additional, Bykov, Alexey G., additional, Akentiev, Alexander B., additional, Noskov, Boris A., additional, Dutta, Kunal, additional, Ghosh, Chandradipa, additional, and Panda, Amiya K., additional

Published
2024
Full Text
View/download PDF

14. Exploring the dual impact of hydrocarbon chainlength and the role of piroxicam a conventional NSAID on soylecithin/ion pair amphiphiles mediated hybrid vesicles for brain – tumor targeted drug delivery

Author

Guha, Pritam, Roy, Biplab, Nahak, Prasant, Karmakar, Gourab, Chang, Chien H., Bikov, Alexey G., Akentiev, Alexander B., Noskov, Boris A., Mandal, Amit K., Kumar, Anoop, Hassan, P.A., Aswal, V.K., Misono, Takeshi, Torigoe, Kanjiro, and Panda, Amiya K.

Published
2018
Full Text
View/download PDF

17. Spread Layers of Lysozyme Microgel at Liquid Surface

Author

Milyaeva, Olga Yu., primary, Akentiev, Alexander V., additional, Bykov, Alexey G., additional, Lin, Shi-Yow, additional, Loglio, Giuseppe, additional, Miller, Reinhard, additional, Michailov, Alexander V., additional, Rotanova, Ksenia Yu., additional, and Noskov, Boris A., additional

Published
2022
Full Text
View/download PDF

19. Spread Layers of Lysozyme Microgel at Liquid Surface

Author

Milyaeva, Olga Yu., Akentiev, Alexander V., Bykov, Alexey G., Lin, Shi-Yow, Loglio, Giuseppe, Miller, Reinhard, Michailov, Alexander V., Rotanova, Ksenia Yu., Noskov, Boris A., Milyaeva, Olga Yu., Akentiev, Alexander V., Bykov, Alexey G., Lin, Shi-Yow, Loglio, Giuseppe, Miller, Reinhard, Michailov, Alexander V., Rotanova, Ksenia Yu., and Noskov, Boris A.

Abstract

The spread layers of lysozyme (LYS) microgel particles were studied by surface dilational rheology, infrared reflection–absorption spectra, Brewster angle microscopy, atomic force microscopy, and scanning electron microscopy. It is shown that the properties of LYS microgel layers differ significantly from those of ß-lactoglobulin (BLG) microgel layers. In the latter case, the spread protein layer is mainly a monolayer, and the interactions between particles lead to the increase in the dynamic surface elasticity by up to 140 mN/m. In contrast, the dynamic elasticity of the LYS microgel layer does not exceed the values for pure protein layers. The compression isotherms also do not exhibit specific features of the layer collapse that are characteristic for the layers of BLG aggregates. LYS aggregates form trough three-dimensional clusters directly during the spreading process, and protein spherulites do not spread further along the interface. As a result, the liquid surface contains large, almost empty regions and some patches of high local concentration of the microgel particles.

Published
2022

20. Impact of Polymer Nanoparticles on DPPC Monolayer Properties

Author

Bykov, Alexey, Milyaeva, Olga, Akentiev, Alexander, Panaeva, Maria, Isakov, Nikolaj, Miller, Reinhard, Noskov, Boris, Bykov, Alexey, Milyaeva, Olga, Akentiev, Alexander, Panaeva, Maria, Isakov, Nikolaj, Miller, Reinhard, and Noskov, Boris

Abstract

The application of surface rheology and Brewster angle microscopy on mixed monolayers of DPPC and polymeric nanoparticles (cationic and anionic) showed that the sign of the particle charge affects the dynamic properties of the monolayers less than the nanoparticles’ ability to aggregate. Under almost physiological conditions, the effect of nanoparticles on the elasticity of DPPC monolayer is insignificant. However, the particles prevent the surface tension from decreasing to extremely low values. This effect could affect the functionality of pulmonary surfactants.

Published
2022

27. Dynamic Surface Properties of Fullerenol Solutions

Author

Noskov, Boris A., primary, Timoshen, Kirill A., additional, Akentiev, Alexander V., additional, Chirkov, Nikolay S., additional, Dubovsky, Ignat M., additional, Lebedev, Vasyli T., additional, Lin, Shi-Yow, additional, Loglio, Giuseppe, additional, Miller, Reinhard, additional, Sedov, Victor P., additional, and Borisenkova, Alina A., additional

Published
2019
Full Text
View/download PDF

28. Biophysical Correlates on the Composition, Functionality, and Structure of Dendrimer–Liposome Aggregates

Author

Roy, Biplab, primary, Guha, Pritam, additional, Nahak, Prasant, additional, Karmakar, Gourab, additional, Maiti, Souvik, additional, Mandal, Amit Kumar, additional, Bykov, Alexey G., additional, Akentiev, Alexander V., additional, Noskov, Boris A., additional, Tsuchiya, Koji, additional, Torigoe, Kanjiro, additional, and Panda, Amiya Kumar, additional

Published
2018
Full Text
View/download PDF

31. Influence of Lipid Core Material on Physicochemical Characteristics of an Ursolic Acid-Loaded Nanostructured Lipid Carrier: An Attempt To Enhance Anticancer Activity

Author

Nahak, Prasant, primary, Karmakar, Gourab, additional, Chettri, Priyam, additional, Roy, Biplab, additional, Guha, Pritam, additional, Besra, Shila Elizabeth, additional, Soren, Anjana, additional, Bykov, Alexey G., additional, Akentiev, Alexander V., additional, Noskov, Boris A., additional, and Panda, Amiya Kumar, additional

Published
2016
Full Text
View/download PDF

33. Evaporation of aqueous solutions of organic acids through spread films of sodium polystyrene sulfonate/dodecyl trimethyl ammonium bromide complex.

Author

Kuznetsov, Viktor, Rakhimov, Viktor, and Akentiev, Alexander

Subjects
ORGANIC acids, EVAPORATION (Chemistry), AQUEOUS solutions, SODIUM compounds, POLYSTYRENE, AMMONIUM bromide
Abstract

The Wilhelmy plate technique was used to determine surface tension isotherms of aqueous solutions of formic and acetic acids with concentration up to 30 vol% and with a film of solution of sodium polystyrene sulfonate/dodecyl trimethyl ammonium bromide complex spread to the surface. The formation conditions of films with the extreme concentration of the complex were determined. Such films reduce the evaporation rate of binary liquids by 3-6% and demonstrate selective properties increasing the water content in the vapor by 2-5 abs%. [ABSTRACT FROM PUBLISHER]

Published
2016
Full Text
View/download PDF

35. Physicochemical Studies on Amino Acid Based Metallosurfactants in Combination with Phospholipid.

Author

Barai, Manas, Manna, Emili, Sultana, Habiba, Mandal, Manas Kumar, Manna, Tuhin, Patra, Anuttam, Roy, Biplab, Gowda, Vasantha, Chang, Chien‐Hsiang, Akentiev, Alexander V., Bykov, Alexey G., Noskov, Boris A., Moitra, Parikshit, Ghosh, Chandradipa, Yusa, Shin‐Ichi, Bhattacharya, Santanu, and Kumar Panda, Amiya

Abstract

Dicarboxylate metallosurfactants (AASM), synthesized by mixing N‐dodecyl aminomalonate, ‐aspartate and ‐glutamate with CaCl2, MnCl2 and CdCl2, were characterized by XRD, FTIR, and NMR spectroscopy. Layered structures, formed by metallosurfactants, were evidenced from differential scanning calorimetry and thermogravimetric analyses. Solvent‐spread monolayer of AASM in combination with soyphosphatidylcholine (SPC) and cholesterol (CHOL) were studied using Langmuir surface balance. With increasing mole fraction of AASM mean molecular area increased and passed through maxima at ~60 mol% of AASMs, indicating molecular packing reorganization. Systems with 20 and 60 mol% AASM exhibited positive deviations from ideal behavior signifying repulsive interaction between the AASM and SPC, while synergistic interactions were established from the negative deviation at other combinations. Dynamic surface elasticity increased with increasing surface pressure signifying formation of rigid monolayer. Transition of monolayer from gaseous to liquid expanded to liquid condensed state was established by Brewster angle microscopic studies. Stability of the hybrid vesicles, formed by AASM+SPC+CHOL, were established by monitoring their size, zeta potential and polydispersity index values over 100 days. Size and spherical morphology of hybrid vesicles were confirmed by transmission electron microscopic studies. Biocompatibility of the hybrid vesicles were established by cytotoxicity studies revealing their possible applications in drug delivery and imaging. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

36. Dynamic surface elasticity of aqueous solutions of polyethylene glycol

Author

A. Noskov, Boris, V. Akentiev, Alexander, A. Alexandrov, Dmitrii, Loglio, Giuseppe, and Miller, Reinhard

Abstract

Measurements of the concentration dependence of the characteristics of surface waves in solutions of polyethylene glycol allow us to determine the dynamic surface elasticity and to show that the relaxation of the surface tension arises as a result of the redistribution of monomers between different regions of the surface layer.

Published
1998

Catalog

Books, media, physical & digital resources
See catalog results