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1. Work-Related Symptoms of Spice Shop Workers and the Effect of Common Aeroallergen Sensitivity on Work-Related Symptoms.

Author

Güngör, Ömür, Akel, Nazan, Şahan, Ceyda, Demir, Ahmet Uğur, and Kalyoncu, Ali Fuat

Subjects
*OCCUPATIONAL disease risk factors, *ALLERGENS, *RISK assessment, *CROSS-sectional method, *OCCUPATIONAL diseases, *QUESTIONNAIRES, *MULTIPLE regression analysis, *LOGISTIC regression analysis, *CUTANEOUS manifestations of general diseases, *ALLERGIES, *CHI-squared test, *MULTIVARIATE analysis, *BUSINESS, *SURVEYS, *ODDS ratio, *RHINORRHEA, *STATISTICS, *SPICES, *DATA analysis software, *CONFIDENCE intervals, *DYSPNEA, *COUGH, *EPIDEMIOLOGICAL research, *SKIN tests, *SYMPTOMS
Abstract

OBJECTIVE: Spices, because of their bioactive content, can cause irritation and allergic symptoms in the respiratory system and skin. Spice shop workers are constantly exposed to spices and dried herbs as part of their jobs. This study aimed to investigate the work-related symptoms of spice shop workers. Another aim was to assess the risk status of having an atopic nature for work-related symptoms. MATERIAL AND METHODS: This was a cross-sectional study. Our research team visited the spice shops and a questionnaire was administered to 112 workers to assess work-related symptoms. In order to determine atopy, 79 of them had skin prick tests with common aeroallergens. RESULTS: Workers had eye complaints (19.6%), runny noses (22.3%), skin symptoms (9.8%), shortness of breath (9.8%), and coughs (19.6%) at work. The prevalence of atopy was 18%. Atopy was associated with work-related eye complaints (odds ratio (OR): 4.12, 95% CI: 1.17-14.46), work-related runny nose, and work-related cough (OR: 4.85, 95% CI: 1.44-16.32, and OR: 4.41, 95% CI: 1.30-14.97). CONCLUSIONS: The workers in spice shops are adversely affected by spices and dried herbs in their working environment. Being sensitive to common aeroallergens poses a risk for occupational symptoms. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Primer glomerulonefrite bağlı kronik böbrek hastalığında proteinürinin böbrek fonksiyonlarındaki bozulma üzerine etkilerinin incelenmesi

Author

Akel, Nazan, Şahin, İdris, and İç Hastalıkları Anabilim Dalı

Subjects
Kidney function tests, Proteinuria, Nefroloji, Kidney diseases, Glomerulonephritis, Nephrology, Glomerular filtration, Kidney failure-chronic, Glomerular filtration rate
Abstract

Amaç: Kronik böbrek hastalığının ilerlemesi çeşitli risk faktörlerininetkilerine bağlıdır. Proteinüride bu risk faktörlerinin en önemlilerinden biridir.Yapılan çalışmalar incelendiğinde şimdiye kadar KBY'li hastalarda proteinürininrenal progresyona etkisini araştıran sınırlı sayıda çalışmaya rastlanmıştır.Çalışmamızda kronik böbrek yetmezlikli hastalarda proteinürinin renal progresyonüzerine olan etkilerini araştırmayı amaçladık.Yöntem ve Gereçler: Araştırmamız, için gerekli olan tetkikler, İnönüÜniversitesi Turgut Özal Tıp Merkezi dosya arşiv bölümü ve Hastane OtomasyonSistemi (Enlil) kullanılarak elde edilmiştir. İnönü Üniversitesi Tıp Fakültesitarafından etik kurulu onayı alındı. Çalışmaya alınacak hastalardan yazılı onamalındı. Hastaların adı, soyadı, dosya numarası, telefon numarası, yaşı, cinsiyeti,hastalığın başlangıç süresi, varsa biyopsi tarihi, böbrek yetmezliğinin sebebi,komorbit hastalıkları, kullandığı ilaçlar araştırıldı ve çalışma formuna kaydedildi.Www.mdrd.com adresinden hastaların GFH hesaplandı ve çalışma formunakaydedildi.Bulgular: Çalışmaya 77 erkek, 105 bayan toplam 182 hasta alınmıştır.Hastaların yaş ortalaması 44±15 yıl (17-80) idi. Hastaların 108'i primerglomerülonefrit, 74 ü sekonder glomerülonefrit tanılı idi. Çalışmaya alınan hastalardaproteinüri ve GFH ilişkisi ele alındığında ise proteinüri arttıkça GFH de belirgindüşme tesbit edildiği görüldü. Başlangıçta nefrotik düzeyde proteinürisi olanhastalarda non nefrotik düzeyde proteinürisi olan hastalara göre GFH'daki düşüşündaha fazla olduğu tesbit edildi. Çalışmamızda proteinüri ve serum albümin düzeyiarasındaki ilişkiye bakıldığında, proteinüri artıkça serum albümin düzeyinin azaldığıtesbit edildi.Sonuç: KBY'li hastalarda proteinüri önemli bir progresyon göstergesidir.Proteinüri ve GFH arasında zıt bir ilişki bulunmaktadır. KBY li hastaların takibindeproteinüri önemli bir parametre teşkil etmektedir. Aim: The progression of chronic kidney disease due to the effects of various riskfactors. Proteinuria is one of the most important of these risk factors. So far, a limitednumber of studies which research the effect of proteinuria to renal disease'sprogression were found. We aimed to investigate the effects of proteinuria to renalprogression in patients with chronic renal failure.Materials and Method: Tests which are necessary to our investigation are obtainedfrom the file archive department and hospital automation system in İnönüUniversity, Turgut Özal Medical Center. Patients approvals were obtained. Thepatients' name, surname, age, sex, file number, phone number, job, date of onset ofthe disease and date of biopsy,the cause of renal failure, comorbid diseases, drugswere registered to the study form. GFR was calculated through the Www.mdrd.com.Findings: For this study 182 patients were used. 77 of them were men and 105 ofthem were women. 108 patients were diagnosed with primary glomerulonephritis, 74patients were diagnosed with secondary glomerulonephritis. Considering therelationship between proteinuria and GFR in patients, proteinuria was detected asignificant decrease, GFR was increased. The decline of GFH in patient withnephrotic proteinüria was found to be more than the patients with nonnephroticproteinüria. Regarding the relationship between the level of proteinuria and serumalbumin, serum albumin levels decreased with increasing proteinuria was observed.Result: Proteinuria in patients with chronic renal failure is an important indicator ofprogression. There is an opposite relationship between the proteinuria and GFR. Theproteinuria is an important parameter for follow-up of patients with chronic renalfailure. 56

Published
2013

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