Search

Porous organic salts (POSs) are constructed through a strong charge‐assisted hydrogen bond between sulfonic and amino groups. The molecular design of sulfonic acid, the linker part, enables various porous structures. In the current work, we synthesized p‐terphenyl‐4,4"‐disulfonic acid (TPDS), whose molecular structure can be easily modified by organic synthesis. Combining of TPDS and bulky tri‐p‐tolylmethanamine (TPMA‐Me), which has three methyl groups at each para‐position of the phenyl groups of triphenylmethylamine (TPMA), gave POS with one‐dimensional pore channels having two different types of bottlenecks. The central benzene ring of TPDS is exposed on the surface of the pore. Therefore, we combined 4,4′‐(benzo[c][1,2,5]thiadiazole‐4,7‐diyl)dibenzenesulfonic acid (BTDBS) containing 2,1,3‐benzothiadiazole (BT) with TPMA‐Me, and successfully constructed a one‐dimensional pore channel with a bottleneck of 3.5 Å, by exposing BT to the surface of the pore. BTDBS/TPMA‐Me exhibited a large adsorption/desorption hysteresis of nitrogen because of the bottleneck, electronic state of BT, and larger oxygen adsorption than the isostructural TPDS/TPMA‐Me. Systematic and intended modulation of the pore structure of POS based on the modification of sulfonic acid was demonstrated, and for the first time, we established a precise design methodology for a one‐dimensional pore channel with a bottleneck and high crystallinity in metal‐free porous organic materials. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate the efficacy of vitrectomy with epiretinal proliferation (EP) sparing for full-thickness macular hole (FTMH) accompanied by EP., Methods: A multicenter, retrospective study. Eyes were divided into two groups: the sparing group (Group S) included eyes in which the EP around the hole was peeled and preserved, whereas the removal group (Group R) included eyes in which the EP was partially or completely removed. The internal limiting membrane was peeling in all eyes., Results: Forty-six eyes were included. Twenty-five eyes were in Group S, and 21 eyes were in Group R, with no difference in preoperative best-corrected visual acuity (BCVA) (P = 0.96). After primary surgery, MHs were closed in all eyes, and there were no complications in either group. Postoperative 12-month BCVA significantly improved in both groups (both P < 0.01), while Group S had better 12-month BCVA than Group R (P = 0.016). In the multivariable analysis, EP sparing was associated with better BCVA at 12 months (P = 0.006) after accounting for the minimal macular hole size and preoperative BCVA., Conclusions: EP sparing and removal were both safe and effective techniques, while EP sparing may provide a favorable outcome for eyes with FTMH and EP.