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3. List of contributors

Author

Aftab, Bushra, primary, Aggarwal, Geeta, additional, Ajmal, Gufran, additional, Alex, Thomson Santosh, additional, Alexander, Amit, additional, Arora, Vimal, additional, Arya, K.R., additional, Babu, R. Jayachandra, additional, Bairagi, Ujjawal, additional, Balamuralidhara, V., additional, Baldi, Ashish, additional, Basetty, Vindhya, additional, Bhatt, Shailendra, additional, Bhatti, Rajbir, additional, Chakraborty, Souvik, additional, Chaturvedi, Sushma, additional, Chandran, C. Sarath, additional, Chaudhary, Sagar, additional, Chauhan, Sonal, additional, Chellappan, Dinesh Kumar, additional, Deruiter, Jack, additional, Dhanasekaran, Muralikrishnan, additional, Dhiman, Anju, additional, Dua, Kamal, additional, Dureja, Harish, additional, Farooq, Uzma, additional, Gautam, Rupesh K., additional, Gulati, Monica, additional, Gulati, Nisha, additional, Gupta, Gaurav, additional, Gupta, N. Vishal, additional, Gupta, Rishabh, additional, Halder, Nabamita, additional, Harrell, Erin, additional, Hassan, Nazia, additional, Iqbal, Zeenat, additional, Jain, Pooja, additional, Jha, Niraj Kumar, additional, Kabra, Atul, additional, Kanojia, Neha, additional, Kapoor, Devesh U., additional, Kapoor, Ramit, additional, Kappally, Shijina, additional, Khursheed, Rubiya, additional, Kumar, Ashutosh, additional, Kumar, Deepak, additional, Kumar, Nitesh, additional, Kumar, Vijay, additional, Lawson, Joseph, additional, Mahajan, Dhriti, additional, Maurya, Pawan Kumar, additional, Mehra, Akansha, additional, Mirza, Mohd. Aamir, additional, Mishra, Brahmeshwar, additional, Mishra, Monalisa, additional, Mittal, Pooja, additional, Mohapatra, Sradhanjali, additional, Naman, Subh, additional, Naryal, Srishti, additional, Neethimohan, Nishitha, additional, Paliwal, Shivani Rai, additional, Palliwal, Rishi, additional, Parise, Rachel, additional, Pathak, Kamla, additional, Pathak, Suhrud, additional, Pondugula, Satyanarayana, additional, Prabitha Priyadharshini, A., additional, Prabu, S. Lakshmana, additional, Prasher, Parteek, additional, Priya, Sakshi, additional, Puratchikody, A., additional, Puri, Ritika, additional, Raizaday, Abhay, additional, Raj, Alan, additional, Rawat, Sushama, additional, Sajayan, Krishnameera, additional, Sapra, Bharti, additional, Sara Josen, Teenu, additional, Sastri, K. Trideva, additional, Sharadha, M., additional, Sharma, Jai Bharti, additional, Sharma, Ram Babu, additional, Sharma, Vijay, additional, Shelke, Triveni, additional, Singh, Lovedeep, additional, Singh, Mahaveer, additional, Singh, Manvi, additional, Singh, Sachin Kumar, additional, Singh, Santosh Kumar, additional, Singla, Chhavi, additional, Singla, Rajeev K., additional, Srivastava, Nimisha, additional, Swathy, K.K., additional, Talegaonkar, Sushma, additional, Thapa, Komal, additional, Tiwary, Ashok Kumar, additional, Tyagi, Anchal, additional, Umamaheswari, A., additional, Upadhyay, Mansi, additional, Vats, Vishal, additional, Verma, Nitin, additional, Verma, Priyanka, additional, Vijayalakshmi, M., additional, Vishwas, Sukriti, additional, Vyas, Govind, additional, and Zakir, Foziyah, additional

Published
2022
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27. Electrospun nanofiber-based drug delivery platform: advances in diabetic foot ulcer management

Author

Jha, Abhishek, Kumar, Manish, Ajmal, Gufran, Bonde, Gunjan Vasant, and Mishra, Brahmeshwar

Abstract

ABSTRACTIntroductionElectrospinning is a facile and viable method for the fabrication of nanofibers. Electrospun nanofiber has a great potential in providing local drug or therapeutic molecule delivery to the wound site. The versatile nature of this technique ensures a broad scope of material used in the fabrication of nanofibers.Area coveredA brief introduction to diabetic foot ulcer (DFU) is covered with its pathogenesis, followed by the role of electrospun nanofibers in DFU. This review covers the evolution of the electrospinning technique over the past few years, various types of electrospun nanofibers reported for DFU or chronic diabetic wounds, the challenges associated with the preparation of nanofibers, and various methods to evaluate their efficacy and performance in diabetic wound healing.Expert opinionElectrospinning-based nanofibers provide a safe, effective, and multifunctional system for effective management of DFU.

Published
2021
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28. Formulation, optimization, hemocompatibility and pharmacokinetic evaluation of PLGA nanoparticles containing paclitaxel.

Author

Mittal, Pooja, Vardhan, Harsh, Ajmal, Gufran, Bonde, Gunjan Vasant, Kapoor, Ramit, Mittal, Ashu, and Mishra, Brahmeshwar

Subjects
PHARMACOKINETICS, NANOPARTICLES, PACLITAXEL, SURFACE active agents, NANOTUBES
Abstract

Objective: Paclitaxel (PTX)-loaded polymer (Poly(lactic-co-glycolic acid), PLGA)-based nanoformulation was developed with the objective of formulating cremophor EL-free nanoformulation intended for intravenous use. Significance: The polymeric PTX nanoparticles free from the cremophor EL will help in eliminating the shortcomings of the existing delivery system as cremophor EL causes serious allergic reactions to the subjects after intravenous use. Methods and results: Paclitaxel-loaded nanoparticles were formulated by nanoprecipitation method. The diminutive nanoparticles (143.2 nm) with uniform size throughout (polydispersity index, 0.115) and high entrapment efficiency (95.34%) were obtained by employing the Box-Behnken design for the optimization of the formulation with the aid of desirability approach-based numerical optimization technique. Optimized levels for each factor viz. polymer concentration (X1), amount of organic solvent (X2), and surfactant concentration (X3) were 0.23%, 5 ml %, and 1.13%, respectively. The results of the hemocompatibility studies confirmed the safety of PLGA-based nanoparticles for intravenous administration. Pharmacokinetic evaluations confirmed the longer retention of PTX in systemic circulation. Conclusion: In a nutshell, the developed polymeric nanoparticle formulation of PTX precludes the inadequacy of existing PTX formulation and can be considered as superior alternative carrier system of the same. [ABSTRACT FROM AUTHOR]

Published
2019
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30. Electrospun nanofiber-based drug delivery platform: advances in diabetic foot ulcer management.

Author

Madhukiran Dr, Jha A, Kumar M, Ajmal G, Bonde GV, and Mishra B

Subjects
Drug Delivery Systems, Humans, Wound Healing, Diabetes Mellitus, Diabetic Foot drug therapy, Nanofibers, Pharmaceutical Preparations
Abstract

Introduction: Electrospinning is a facile and viable method for the fabrication of nanofibers. Electrospun nanofiber has a great potential in providing local drug or therapeutic molecule delivery to the wound site. The versatile nature of this technique ensures a broad scope of material used in the fabrication of nanofibers., Area Covered: A brief introduction to diabetic foot ulcer (DFU) is covered with its pathogenesis, followed by the role of electrospun nanofibers in DFU. This review covers the evolution of the electrospinning technique over the past few years, various types of electrospun nanofibers reported for DFU or chronic diabetic wounds, the challenges associated with the preparation of nanofibers, and various methods to evaluate their efficacy and performance in diabetic wound healing., Expert Opinion: Electrospinning-based nanofibers provide a safe, effective, and multifunctional system for effective management of DFU.

Published
2021
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