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The aim of this study was to assess awareness among the students of the Faculty of Dentistry of the University of Sarajevo of the occupational health risks associated with dental profession. The research was conducted among the dental students of all years of study at the Faculty of Dentistry of the University of Sarajevo, by using a tailor-made survey questionnaire. The questionnaire was completed by 446 students. Results: 92% of students believe that dentistry is a profession that involves a high level of risk for the outbreak of occupational diseases. Students believe that practicing dentistry can most often lead to various infections (70%) and vision impairments (64%), and that the most common potential causes of occupational diseases are poor positioning and incorrect body posture during work (88%) and infections (78%). When asked whether the occupational diseases among dentists are preventable, 89% of students gave an affirmative answer, and pointed to the requirement to use Personal Protection Equipment – PPE (94%) as the most important measure for the prevention of occupational diseases among dentists. The results of the survey show that the students of dentistry at the Faculty of Dentistry of the University of Sarajevo have reached a certain level of awareness of the health risks that are associated with their future profession. The students have taken a largely identical view that dentistry is a profession that involves a high level of risk for the development of occupational diseases.

Objectives: The development of third molars can be helpful in dental age estimation of adolescents and in early adult period. We tested the repeatability and accuracy of the three dental age radio-graphic methods (Olze, Demirjian and Solari and Abramovitch) and evaluated which method is more useful. We also aimed at testing to find the correlation of estimated dental and chronological age by these three methods. Material and methods: The orthopantomographs (OPGs) of 1007 individuals (8 - 25 years) were divided into two groups (cca 500 OPGs) – one group of OPGs has been presented with all four third molars, while another one was registered with third molar/s hypodontia. And all of OPGs were assessed, to verify the three methods (Olze, Demirjian and Solari and Abramovitch) for age estimation based on third molar development. Results: There was a high Spearman’s correlation coefficient between stages of development of wisdom tooth and chronological age of subjects by all these three methods. Conclusion: We may recommend using third molars for assessing the dental age by Olze, Demirjian and Solari and Abramovitch dental method as well, on Bosnian and Herzegovinian population.

Four 4-hydroxycoumarin derivatives were synthesized and the structure was confirmed by NMR spectroscopy and Mass spectrometry. Tested compounds have shown significant antimicrobial activity against Bacillus subtilis subsp. spizizenii, Bacillus cereus, Staphylococcus aureus, and Staphylococcus epidermidis, and the effect of more halogens on the benzene nucleus, as well as the combination of halogen and alkyl groups, on the antimicrobial activity, was investigated. According to the docking study, these compounds can operate simultaneously on two enzymes, amylase and gyrase (1BAG and 1KZN), which are known to play an important role in bacterial life. Obtained docking study parameters for tested compounds showed an association with the in vitro results of the antimicrobial activity of these compounds. In silico tests of molecular properties of the tested compounds showed that the compounds met Lipinski's rule of five. In this paper, the ADME parameters of tested compounds were also calculated: Caco2 (in vitro Caco2 cell permeability), HIA (human intestinal absorption), MDCK (in vitro Mandin Darby Canine Kidney (MDCK) cell permeability), TPSA (topological polar surface area), etc. This work is licensed under a Creative Commons Attribution 4.0 International License.

Svrha: Svrha istraživanja bila je pronaći poveznicu između eruptivnih stadija trećih maksilarnih i mandibularnih kutnjaka s lijeve i desne strane čeljusti. Materijali i metode: Uzorak istraživanja činilo je 529 ortopantomograma (OPG-a) – 264 (49,9 %) pripadalo je muškom spolu, a 265 (50,1 %) ženskom spolu u dobi između 8 i 25 godina. Sudionici su bili prema Olzeovoj metodi podijeljeni u šest dobnih skupina. Rezultati: Dobivene su visoke vrijednosti Spearmanova koeficijenta povezanosti između eruptivnih stadija lijevih i desnih maksilarnih i mandibularnih trećih molara. Između spolova nisu pronađene statistički značajne razlike u eruptivnim stadijima. Zaključak: Prema dobivenim rezultatima za procjenu dentalne dobi u bosansko-hercegovačkoj populaciji, preporučujemo Olzeovu metodu i treće mandibularne molare. Treba istaknuti da su moguće razvojne asimetrije i da svaki dentalni antropolog mora biti svjestan te činjenice. Svaka strana čeljusti trebala bi se posebno procjenjivati., Aim: The aim of this study was to assess the correlation of eruptive stages of third molars between right and left side in upper and lower jaws. Material and methods: The sample for this study consisted of 529 OPGs of 264 (49.9%) male and 265 (50.1%) female subjects, aged 8 to 25 years, divided into six groups, with known chronological age, by Olze method. Results: there was a high Spearman’s correlation coefficient between eruptive stages of the right and left lower and upper third molars. Overall, no significant differences were found in third molar eruption between males and females. Conclusion: We recommend using third molars in lower jaws for assessing the dental age by Olze method on Bosnian and Herzegovinian population by using our results. It is important to mention that forensic odontologists must be aware of the fact that asymmetry in development is possible. Both sides should be independently evaluated.