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273 results on '"Ahmed-Farid, Omar"'

31. Lactiplantibacillus plantarum and Saussurea costus as Therapeutic Agents against a Diabetic Rat Model—Approaches to Investigate Pharmacophore Modeling of Human IkB Kinase and Molecular Interaction with Dehydrocostus Lactone of Saussurea costus

Author

AlGeffari, Metab A., primary, Mansour, Dina, additional, Ahmed-Farid, Omar, additional, Mohamed Yousef, Einas, additional, Mohamed, Shereen A., additional, Moustafa, Mahmoud M. A., additional, Barakat, Hassan, additional, and Abd El Ghany, Khalid, additional

Published
2023
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34. Enhancing semen quality, brain neurotransmitters, and antioxidant status of rabbits under heat stress by acacia gum, vitamin C, and lycopene as dietary supplements: an in vitro and in silico study.

Author

Imbabi, Tharwat A., Habashy, Walid S., Abol-Fetouh, Ghada M., Labib, Mai M., Osman, Ali, Elkelish, Amr, Qurtam, Ashraf A., Tantawi, Abuelkassem A., and Ahmed-Farid, Omar

Subjects
SEMEN analysis, GUM arabic, OXIDANT status, LYCOPENE, NEUROTRANSMITTERS, PHYSIOLOGICAL effects of heat, VITAMIN C
Abstract

In the current study, the effects of enhancing semen quality, brain neurotransmitters, and antioxidant status in rabbits under heat stress with acacia gum, vitamin C, and lycopene as dietary supplements were estimated in vitro and in silico. A total of 40 males from New Zealand White rabbits aged 3 months were equally divided into four groups (n = 10). The first group was a control. The other three groups were the heat stress group (oral acacia gum, 100 mg/kg body weight), the ascorbic acid group (30 mg/kg body weight), and the lycopene group (50 mg/kg body weight). All semen showed physical characteristics in terms of increasing sperm motility, motility index, sperm normality, and live sperm as compared to the control group. On the other hand, sperm abnormalities, and dead sperm significantly (p < 0.001) decreased compared with the control group. It is of interest to show that most semen traits were significantly (p < 0.001) better for acacia gum than vitamin C and lycopene. The expression of neurotransmitters (5-HT, DA, Glu, Asp) was enhanced in all treatments compared to the control. The results of acacia gum were better (p < 0.001) than those obtained with vitamin C and lycopene. The acacia gum treatment had a lower plasma semen MDA and NO (p < 0.001) and higher GSH, TAC, SOD, CAT, L-Car, Na+-K+ ATPase, ATP, and total calcium content (p < 0.001) than in other treatments and controls. These results were confirmed by the prediction of the binding energy, several conventional and carbon H-bonds, hydrophobicity, and SAS through the in silico docking analysis results. It can be concluded that acacia gum, vitamin c, and lycopene are used for enhancing semen quality, brain neurotransmitters, and the antioxidant status of rabbits under heat stress. One of the most significant influences on animal metabolism and productivity is heat stress. Fertility is negatively impacted by heat stress because the level of reactive oxygen species rises. Acacia gum, lycopene, and ascorbic acid were used to improve the quality of sperm, brain neurotransmitters, and antioxidant status of rabbits under heat stress in vivo. [ABSTRACT FROM AUTHOR]

Published
2023
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38. Dietary Supplementation of Silybum marianum Seeds Improved Growth Performance and Upregulated Associated Gene Expression of Muscovy Ducklings (Cairina moschata)

Author

El-Garhy, Osama, primary, Soudy, Fathia A., additional, Alharbi, Yousef M., additional, Alshanbari, Fahad A., additional, Almujaydil, Mona S., additional, Alhomaid, Raghad M., additional, Ahmed-Farid, Omar A., additional, Mohamed, Shereen A., additional, El-Garhy, Hoda A. S., additional, Barakat, Hassan, additional, and EL Nagar, Ayman G., additional

Published
2022
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41. Chemical Profile of Cyperus laevigatus and Its Protective Effects against Thioacetamide-Induced Hepatorenal Toxicity in Rats

Author

Ayoub, Iriny M., primary, El-Baset, Marawan A., additional, Elghonemy, Mai M., additional, Bashandy, Samir A. E., additional, Ibrahim, Fatma A. A., additional, Ahmed-Farid, Omar A. H., additional, El Gendy, Abd El-Nasser G., additional, Afifi, Sherif M., additional, Esatbeyoglu, Tuba, additional, Farrag, Abdel Razik H., additional, Farag, Mohamed A., additional, and Elshamy, Abdelsamed I., additional

Published
2022
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43. Effect of Using Dried Microalgae as Growth Promoters for Nile Tilapia: Growth, Hematology and Related Genes Expression.

Author

Moawad, Dina A., Ahmed-Farid, Omar, El-Garhy, Hoda A. S., Hassaan, Mohamed S., and Refaat, Mohamed H.

Subjects
*FISH feeds, *NILE tilapia, *SOMATOTROPIN receptors, *GENE expression, *ERYTHROCYTES, *WEIGHT gain, *MICROALGAE, *HEMORHEOLOGY
Abstract

In Nile tilapia, Oreochromis niloticus, dietary dry Golenkinia longispicula supplementation (0.0, 5, 10 and, 15 g kg-1 diets) was utilized to improve growth, feed efficiency, and hematologically related gene expression. Fingerlings weighing 3.29 ± 0.16 g at hatching were randomized and placed in triplicate into twelve fiberglass tanks measuring 0.5 m3 and holding 250 L of water for each treatment. After 90 days of the feeding trial, the results demonstrated final body weight (FBW), weight gain (WG), specific growth rate (SGR), and feed conversion ratio (FCR) were significantly (P < 0.05) improved by a diet contained 15 g kg-1 G. longispicula. The highest hematocrit (Hct), hemoglobin (Hb), and red blood cells (RBCs) levels were detected in the fish-fed diet that had 15 g of G. longispicula kg-1. The values of growth hormone (GH) and growth hormone receptor were upregulated fish fed a diet that included 15 g kg-1 diet of dry G. longispicula. [ABSTRACT FROM AUTHOR]

Published
2023
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45. Chemical Profile of Cyperus laevigatus and Its Protective Effects against Thioacetamide-Induced Hepatorenal Toxicity in Rats

Author

Ayoub, Iriny M., El-Baset, Marawan A., Elghonemy, Mai M., Bashandy, Samir A. E., Ibrahim, Fatma A. A., Ahmed-Farid, Omar A. H., El Gendy, Abd El-Nasser G., Afifi, Sherif M., Esatbeyoglu, Tuba, Farrag, Abdel Razik H., Farag, Mohamed A., Elshamy, Abdelsamed I., Ayoub, Iriny M., El-Baset, Marawan A., Elghonemy, Mai M., Bashandy, Samir A. E., Ibrahim, Fatma A. A., Ahmed-Farid, Omar A. H., El Gendy, Abd El-Nasser G., Afifi, Sherif M., Esatbeyoglu, Tuba, Farrag, Abdel Razik H., Farag, Mohamed A., and Elshamy, Abdelsamed I.

Abstract

Cyperus species represent a group of cosmopolitan plants used in folk medicine to treat several diseases. In the current study, the phytochemical profile of Cyperus laevigatus ethanolic extract (CLEE) was assessed using UPLC-QTOF–MS/MS. The protective effect of CLEE at 50 and 100 mg /kg body weight (b.w.) was evaluated on hepatorenal injuries induced by thioacetamide (100 mg/kg) via investigation of the extract’s effects on oxidative stress, inflammatory markers and histopathological changes in the liver and kidney. UPLC-QTOF–MS/MS analysis of CLEE resulted in the identification of 94 compounds, including organic and phenolic acids, flavones, aurones, and fatty acids. CLEE improved the antioxidant status in the liver and kidney, as manifested by enhancement of reduced glutathione (GSH) and coenzyme Q10 (CoQ10), in addition to the reduction in malondialdehyde (MDA), nitric oxide (NO), and 8-hydroxy-2′-deoxyguanosine (8OHdG). Moreover, CLEE positively affected oxidative stress parameters in plasma and thwarted the depletion of hepatorenal ATP content by thioacetamide (TAA). Furthermore, treatment of rats with CLEE alleviated the significant increase in plasma liver enzymes, kidney function parameters, and inflammatory markers. The protective effect of CLEE was confirmed by a histopathological study of the liver and kidney. Our results proposed that CLEE may reduce TAA-hepatorenal toxicity via its antioxidant and anti-inflammatory properties suppressing oxidative stress.

Published
2022

46. Anticancer and Neuroprotective Activities of Ethyl Acetate Fractions from Morus macroura Miq. Plant Organs with Ultraperformance Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry Profiling

Author

Hamdan, Dalia Ibrahim, primary, Salah, Samia, additional, Hassan, Wafaa Hassan Badr, additional, Morsi, Mai, additional, Khalil, Heba Muhammed Ali, additional, Ahmed-Farid, Omar Abdel-hamed, additional, El-Shiekh, Riham Adel, additional, Nael, Manal AbdElaziz, additional, and Elissawy, Ahmed Mohamed, additional

Published
2022
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