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5. Contributors

Author

Abaterusso, Cataldo, primary, Ahern, Stéphane P., additional, Aisa, Maria Cristina, additional, Albright, Robert C., additional, Alfaro, Vicente, additional, Al-Khafaji, Ali, additional, Allo, Jean-Christophe, additional, Amerling, Richard, additional, Amore, Alessandro, additional, Anderson, Robert J., additional, Andreucci, Michele, additional, Andreucci, Vittorio E., additional, Andrikos, Emilios, additional, Arroyo, Vicente, additional, Arthur, John M., additional, Ash, Stephen R., additional, Assanelli, Emilio, additional, Aucella, Filippo, additional, Bagshaw, Sean M., additional, Balafa, Olga, additional, Balbi, André Luís, additional, Baldwin, Ian, additional, Ballestri, Marco, additional, Bargman, Joanne M., additional, Barletta, Gina-Marie, additional, Barletta, Jeffrey F., additional, Barozzi, Libero, additional, Barsoum, Rashad S., additional, Beaulieu, Monica, additional, Beer-Stolz, Donna, additional, Bellomo, Rinaldo, additional, Bernardo, Jose, additional, Bertolotto, Michele, additional, Bestoso, John T., additional, Betro, Gerard A., additional, Bhattacharya, Mallar, additional, Bihl, Geoffrey R., additional, Blot, Stijn I., additional, Boer, Willem, additional, Boim, Mirian A., additional, Bonello, Monica, additional, Bonventre, Joseph V., additional, Booth, A.D., additional, Bourke, Edmund, additional, Braitberg, George, additional, Brancaccio, Diego, additional, Brendolan, Alessandra, additional, Brezzi, Brigida, additional, Brodie, James C., additional, Brophy, Patrick D., additional, Brown, Ryan, additional, Bucala, Richard, additional, Buckmaster, Jonathan, additional, Budisavljevic, Milos N., additional, Bunchman, Timothy E., additional, Burdmann, Emmanuel A., additional, Bussolati, Benedetta, additional, Butkus, Matthew A., additional, Buzzelli, Daniela, additional, Calzavacca, Paolo, additional, Camussi, Giovanni, additional, Canaud, Bernard, additional, Cano, Noël J.M., additional, Cantaluppi, Vincenzo, additional, Capasso, Giovambattista, additional, Cappelli, Gianni, additional, Carlesso, Eleonora, additional, Casino, Francesco G., additional, Castillo, Leticia, additional, Cerutti, Roberta, additional, Chawla, Lakhmir S., additional, Chionh, Chang Yin, additional, Chiu, Alexander, additional, Chow, May T., additional, Chugh, Kirpal S., additional, Cianciaruso, Bruno, additional, Cignarelli, Mauro, additional, Claessens, Yann-Erick, additional, Clark, John A., additional, Clark, William R., additional, Cohen, David J., additional, Cohen, Scott D., additional, Constable, Peter, additional, Coppo, Rosanna, additional, Corey, Howard E., additional, Cozzolino, Mario, additional, Craig, Maureen, additional, Cramer, Carl H., additional, Crandall, Mark, additional, Cravedi, Paolo, additional, Crepaldi, Carlo, additional, Crew, R. John, additional, Cronin, Donald F., additional, Cruz, Dinna N., additional, Canton, Antonio Dal, additional, Dan, Maurizio, additional, D'Angelo, Angela, additional, Davenport, Andrew, additional, Davies, Andrew R., additional, Dear, James W., additional, Gasperi, Andrea De, additional, Dell'Aquila, Roberto, additional, Rocca, Giorgio Della, additional, Prete, Dorella Del, additional, Delude, Russell L., additional, Depner, Thomas, additional, Derchi, Lorenzo E., additional, Devarajan, Prasad, additional, Waele, Jan J. De, additional, Dhainaut, Jean-François, additional, Diaz-Buxo, José A., additional, Micco, Lucia Di, additional, Divino-Filho, José Carolina, additional, Doernberg, Sarah, additional, Doig, Gordon S., additional, Dries, David J., additional, Drudi, Francesco Maria, additional, Druml, Wilfred, additional, Duke, Graeme, additional, Durward, Andrew, additional, Egi, Moritoki, additional, Esposito, Ciro, additional, Evenepoel, Pieter, additional, Faga, Teresa, additional, Fan, Sheung Tat, additional, Feinfeld, Donald A., additional, Féraille, Eric, additional, Fernández, Javier, additional, Finfer, Simon, additional, Fink, Mitchell P., additional, Finkel, Kevin W., additional, Flessner, Michael F., additional, Formica, Marco, additional, Forni, Lui G., additional, Fortenberry, James D., additional, French, Craig, additional, Fumagalli, Roberto, additional, Furlanut, Mario, additional, Fute, Micheline Djouguela, additional, Gabriel, Daniela Ponce, additional, Galassi, Andrea, additional, Galbusera, Miriam, additional, Galli, Francesco, additional, Galli, Giovanni, additional, Gallieni, Maurizio, additional, Gallo, Giampiero, additional, Gambaro, Giovanni, additional, Gammill, Hilary S., additional, Gangemi, Ezio Nicola, additional, Gao, Dayong, additional, Garwood, Susan, additional, Garzotto, Francesco, additional, Gatti, Antonietta M., additional, Gattinoni, Luciano, additional, Geibel, John P., additional, George, Stephen, additional, Gesualdo, Loreto, additional, Gibney, R.T. Noel, additional, Gipson, Debbie S., additional, Glezerman, Ilya G., additional, Glorieux, Griet, additional, Goldstein, Stuart L., additional, Golper, Thomas A., additional, Gowrishankar, Manjula, additional, Grandi, Fabio, additional, Gregoretti, Cesare, additional, Grinnell, Brian W., additional, Groeneveld, A.B. Johan, additional, Gruber, Steven J., additional, Guadagni, Gualtiero, additional, Gunnerson, Kyle J., additional, Gupta, Akanksha, additional, Gura, Victor, additional, Guzzo, Isabella, additional, Hackbarth, Richard, additional, Halperin, Mitchell L., additional, Harbord, Nikolas, additional, Haymann, Jean-Philippe, additional, Heffner, Alan C., additional, Hennessy, Anthony J., additional, Heyman, Samuel N., additional, Hill, Graham L., additional, Hilton, Philip J., additional, Himmelfarb, Jonathan, additional, Hirasawa, Hiroyuki, additional, Hoenich, Nicholas A., additional, Holdsworth, Stephen R., additional, Holley, Anthony, additional, Honoré, Patrick M., additional, Hoste, Eric A.J., additional, House, Andrew A., additional, Huang, David T., additional, Huang, Zhongping, additional, Hubmayr, Rolf D., additional, Hughes, Alun D., additional, Humes, H. David, additional, Ikizler, T. Alp, additional, Imberti, Barbara, additional, Ing, Todd S., additional, Jaber, Bertrand L., additional, Janvier, Gérard, additional, Jeyabalan, Arundhathi, additional, Jha, Vivekanand, additional, Joannes-Boyau, Olivier, additional, Joannidis, Michael, additional, Jones, Daryl A., additional, Jörres, Achim, additional, Kamel, Kamel S., additional, Kamp, Ryan C., additional, Kannan, Neeta, additional, Kaplan, Lewis J., additional, Karacan, Özgür, additional, Karajala-Subramanyam, Vijay, additional, Kaushal, Gur P., additional, Kellum, John A., additional, Kemper, Markus J., additional, Khan, Asjad, additional, Khanna, Ramesh, additional, Kher, Vijay, additional, Kimmel, Paul L., additional, Kindgen-Milles, Detlef, additional, Kitching, A. Richard, additional, Kjellstrand, Carl M., additional, Kohn, Orly F., additional, Kooienga, Laura A., additional, Kooman, Jeroen P., additional, Kotanko, Peter, additional, Krediet, Raymond T., additional, Kroon, A.A., additional, Kuang, Dingwei, additional, Kuhlmann, Martin K., additional, Kuiper, Jan Willem, additional, Lam, Man-Fai, additional, Lamacchia, Olga, additional, Lameire, Norbert, additional, Langenberg, Christoph, additional, Lauri, Gianfranco, additional, Leblanc, Martine, additional, Ledebo, Ingrid, additional, Lentini, Paolo, additional, Leonard, Edward F., additional, Letteri, Jeffrey J., additional, Leunissen, Karel M., additional, Leverve, Xavier M., additional, Levin, Adeera, additional, Leypoldt, John K., additional, Liangos, Orfeas, additional, Licari, Elisa, additional, Lieberthal, Wilfred, additional, Linden, Peter K., additional, Lipman, Jeffrey, additional, Liu, Kathleen D., additional, Liu, Shiguang, additional, Livigni, Sergio, additional, Lo, Wai-Kei, additional, Lugano, Manuela, additional, Lui, Sing-Leung, additional, Lupo, Antonio, additional, Luyckx, Valerie A., additional, Macias, William L., additional, Madden, Nicholas, additional, Madore, François, additional, Majors, Daniel S., additional, Mancini, Elena, additional, Mangione, Filippo, additional, Mankad, Sunil, additional, Manzini, Pier Paolo, additional, Marangella, Martino, additional, Marenzi, Giancarlo, additional, Mariano, Filippo, additional, Marik, Paul E., additional, Marini, John J., additional, Marquis, François, additional, Marshall, John C., additional, Marshall, Mark R., additional, Mathew, Roy, additional, Matsuda, Kenichi, additional, Matthay, Michael A., additional, Maxvold, Norma J., additional, May, Clive N., additional, McCauley, Jerry, additional, McCunn, Maureen, additional, McKenna, Joseph, additional, Mehta, Ravindra L., additional, Mele, Caterina, additional, Merouani, Aicha, additional, Mesnard, Laurent, additional, Messa, Piergiorgio, additional, Metnitz, Philipp G.H., additional, Misra, Madhukar, additional, Mitzner, Steffen R., additional, Mizock, Barry A., additional, Mokhlesi, Babak, additional, Molitoris, Bruce A., additional, Morelli, Andrea, additional, Morgan, Thomas John, additional, Morigi, Marina, additional, Mount, Peter, additional, Mucelli, Roberto Pozzi, additional, Mueller, Bruce A., additional, Murray, Patrick, additional, Murugan, Raghavan, additional, Nakamura, Masataka, additional, Nalesso, Federico, additional, Nester, Carla M., additional, Nissenson, Allen, additional, Nolph, Karl, additional, Ocampo, Catalina, additional, Oda, Shigeto, additional, Okusa, Mark D., additional, Opal, Steven M., additional, Opdam, Helen, additional, Osswald, Hartmut, additional, Straaten, Heleen M. Oudemans–van, additional, Padalino, Massimo A., additional, Paden, Matthew L., additional, Paganini, Emil P., additional, Palevsky, Paul M., additional, Panat, Mani John, additional, Paolini, Francesco, additional, Parikh, Dipen, additional, Patroniti, Nicolò, additional, Pavlica, Pietro, additional, de La Garanderie, Didier Payen, additional, Pea, Federico, additional, Peng, Zhiyong, additional, Perazella, Mark A., additional, Perego, Angelo F., additional, Pereira, Estela Regina, additional, Pérez, Evans R. Fernández, additional, Perico, Norberto, additional, Pertica, Nicoletta, additional, Pertosa, Giovanni, additional, Peruzzi, Licia, additional, Petras, Dimitris, additional, Pham, Phuong-Chi, additional, Pham, Phuong-Thu, additional, Phoon, Richard K.S., additional, Picca, Stefano, additional, Piccinni, Pasquale, additional, Pinsk, Maury N., additional, Pinsky, Michael R., additional, Piroddi, Marta, additional, Plamondon, Isabelle, additional, Plank, Lindsay D., additional, Plötz, Frans B., additional, Poghosyan, Lusine, additional, Polanco, Natalia, additional, Polanco, Patricio M., additional, Polaschegg, Hans Dietrich, additional, Ponikvar, Rafael, additional, Porecca, Silvia, additional, Portilla, Didier, additional, Powell, T. Brian, additional, Quigley, Raymond, additional, Rabb, Hamid, additional, Ragaller, Maximilian, additional, Rampino, Teresa, additional, Ranpuria, Reena, additional, Rastogi, Anjay, additional, Ratanarat, Ranistha, additional, Raza, Naem, additional, Reade, Michael C., additional, Reeves, John H., additional, Reiter, Karl, additional, Remuzzi, Giuseppe, additional, Ricci, Zaccaria, additional, Ricksten, Sven-Erik, additional, Ridel, Christophe, additional, Rifai, Kinan, additional, Ring, Troels, additional, Riopel, Julie, additional, Rocha, Eduardo, additional, Roessler, Eric, additional, Rona, Roberto, additional, Ronco, Claudio, additional, Rondeau, Eric, additional, Rosen, Seymour, additional, Rosenberger, Christian, additional, Rowan, Shane, additional, Roy, Thomas, additional, Saab, Georges, additional, Sadahiro, Tomohito, additional, Sala, Carla, additional, Sala, Chiara, additional, Salama, Alan D., additional, Salmon, Adrian, additional, Salvatori, Gabriela, additional, Sam, Ramin, additional, Sandoval, Ruben M., additional, Santoro, Antonio, additional, Saotome, Takao, additional, Sappington, Penny L., additional, Sarma, J. Vidya, additional, Savige, Judy, additional, Schena, Francesco Paolo, additional, Schepers, Eva, additional, Schetz, Miet, additional, Schmidt, Gregory A., additional, Schor, Nestor, additional, Schusterschitz, Nicola, additional, Segoloni, Giuseppe, additional, Shah, Nirva, additional, Shah, Shamik H., additional, Shah, Sudhir V., additional, Sharfuddin, Asif A., additional, Shaw, Andrew, additional, Shiga, Hidetoshi, additional, Shoji, Hisataka, additional, Shukla, Ashutosh, additional, Simpson, Fiona, additional, Singbartl, Kai, additional, Singer, Mervyn, additional, Solez, Kim, additional, Sowinski, Kevin M., additional, Stafford-Smith, Mark, additional, Stange, Jan, additional, Stefanelli, Luca, additional, Stein, Deborah M., additional, Stella, Maurizio, additional, Stellin, Giovanni, additional, Story, David A., additional, Subramanian, Sanjay, additional, Swärd, Kristina, additional, Symons, Jordan M., additional, Tai, Kian Bun, additional, Tattersall, James, additional, Tedeschi, Luisa, additional, Teitelbaum, Isaac, additional, Teixeira, Vicente P. Castro, additional, Tetta, Ciro, additional, Thakar, Charuhas V., additional, Theilen, Hermann, additional, Thomas, Karl W., additional, Tolwani, Ashita, additional, Trepiccione, Francesco, additional, Triolo, Giorgio, additional, Tsang, Jennifer L.Y., additional, Tutal, Emre, additional, Uchino, Shigehiko, additional, Unruh, Mark, additional, Vail, G. Matthew, additional, Valentino, Massimo, additional, Vallon, Volker, additional, Van Biesen, Wim, additional, van der Sande, Frank M., additional, Vandijck, Dominique M., additional, Vanholder, Raymond, additional, Varghese, Sanju A., additional, Venkataraman, Ramesh, additional, Venkatesh, Bala, additional, Verbine, Anton, additional, Vincent, Jean-Louis, additional, Vinsonneau, Christophe, additional, Visvanathan, Ravindran, additional, Voinescu, Alexandra, additional, Walters, Scott, additional, Wan, Li, additional, Ward, Peter A., additional, Ward, Richard A., additional, Warrillow, Stephen, additional, Webb, Steve, additional, Whitlow, Kenneth Scott, additional, Wieslander, Anders, additional, Wilkinson, Alan H., additional, Wille, Keith, additional, Winchester, James Frank, additional, Wu, Christine, additional, Yassin, James, additional, Yeun, Jane Y., additional, Yip, Terence Pok-Siu, additional, Yu, Alex W., additional, Zacchia, Miriam, additional, Zaida, Najam, additional, Zamperetti, Nereo, additional, Zappitelli, Michael, additional, and Zarbock, Alexander, additional

Published
2009
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6. Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada

Author

Kumar, Anand, Zarychanski, Ryan, Pinto, Ruxandra, Cook, Deborah J., Marshall, John, Lacroix, Jacques, Stelfox, Tom, Bagshaw, Sean, Choong, Karen, Lamontagne, Francois, Turgeon, Alexis F., Lapinsky, Stephen, Ahern, Stéphane P., Smith, Orla, Siddiqui, Faisal, Jouvet, Philippe, Khwaja, Kosar, McIntyre, Lauralyn, Menon, Kusum, Hutchison, Jamie, Hornstein, David, Joffe, Ari, Lauzier, Francois, Singh, Jeffrey, Karachi, Tim, Wiebe, Kim, Olafson, Kendiss, Ramsey, Clare, Sharma, Sat, Dodek, Peter, Meade, Maureen, Hall, Richard, and Fowler, Robert A.

Published
2009
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13. Le don de cornée : l'expérience des médecins résidents juniors et l'évaluation préliminaire de leurs besoins de formation.

Author

DOYLE, Tina Karine, AHERN, Stéphane P., MATHIEU, Annabelle, and MARQUIS, François

Subjects
*CORNEAL transplantation, *OPHTHALMIC surgery, *MEDICAL students, *EYE banks, *TRANSPLANTATION of organs, tissues, etc.
Abstract

Background: The number of corneal transplants in Canada does not meet demand, largely due to the inadequate number of corneas collected. Physician trainees can play an active role in the process of pledging and promoting corneal donation because they spend a considerable amount of time at the bedside. A specific training program for residents could help improve the situation. From this standpoint, it is first necessary to find out what is important for residents regarding this issue and what the obstacles to corneal donation are. Aims: 1) To collect the experience of junior physician trainees vis-à-vis corneal donation, evaluate their knowledge, assess their attitudes and perceptions with respect to the issue, gather facilitators and barriers; 2) to determine the perceived training needs of medical students. Methods: As this study is a preliminary evaluation of junior medical residents' training needs regarding corneal donation, we conducted 17 semi-directed interviews on an individual basis. A thematic content analysis was later carried out. Results: The attitudes and perceptions of junior physician trainees regarding corneal donation are positive. However, they know very little about the topic and forget to discuss it with the families of potential donors. They are interested in having formative training to learn more and be able to answer possible questions. Conclusion: In order to increase the amount of both corneal donors and transplants, it seems that there is a need to set up lectures specifically designed for medical students. Consulting all other stakeholders involved in the process (teachers, physicians, donation nurses and eye banks) as well as using other need analysis tools would help develop more grounded and effective student training on the issue. [ABSTRACT FROM AUTHOR]

Published
2012
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14. Enteric absorption and pharmacokinetics of oseltamivir in critically ill patients with pandemic (H1N1) influenza

Author

Ariano, Robert E., Sitar, Daniel S., Zelenitsky, Sheryl A., Zarychanski, Ryan, Pisipati, Amarnath, Ahern, Stéphane, Kanji, Salmaan, Rello, Jordi, and Kumar, Anand

Abstract

BACKGROUND: Whether the enteric absorption of the neuraminidase inhibitor oseltamivir is impaired in critically ill patients is unknown. We documented the pharmacokinetic profile of oseltamivir in patients admitted to intensive care units (ICUs) with suspected or confirmed pandemic (H1N1) influenza. METHODS: We included 41 patients 18 years of age and older with suspected or confirmed pandemic (H1N1) influenza who were admitted for ventilatory support to nine ICUs in three cities in Canada and Spain. Using tandem mass spectrometry, we assessed plasma levels of oseltamivir free base and its active metabolite carboxylate at baseline (before gastric administration of the drug) and at 2, 4, 6, 9 and 12 hours after the fourth or later dose. RESULTS: Among the 36 patients who did not require dialysis, the median concentration of oseltamivir free base was 10.4 (interquartile range [IQR] 4.8–14.9) µg/L; the median concentration of the carboxylate metabolite was 404 (IQR 257–900) µg/L. The volume of distribution of the carboxylate metabolite did not increase with increasing body weight (R2= 0.00, p = 0.87). The rate of elimination of oseltamivir carboxylate was modestly correlated with estimations of creatinine clearance (R2= 0.27, p < 0.001). Drug clearance in the five patients who required continuous renal replacement therapy was about one-sixth that in the 36 patients with relatively normal renal function. INTERPRETATION: Oseltamivir was well absorbed enterically in critically ill patients admitted to the ICU with suspected or confirmed pandemic (H1N1) influenza. The dosage of 75 mg twice daily achieved plasma levels that were comparable to those in ambulatory patients and were far in excess of concentrations required to maximally inhibit neuraminidase activity of the virus. Adjustment of the dosage in patients with renal dysfunction requiring continuous renal replacement therapy is appropriate; adjustment for obesity does not appear to be necessary.

Published
2010

16. Residents' end-of-life decision making with adult hospitalized patients: a review of the literature.

Author

Gorman TE, Ahern SP, Wiseman J, and Skrobik Y

Subjects
Adult, Humans, Advance Care Planning, Attitude to Death, Decision Making, Hospitalization, Internship and Residency, Physician-Patient Relations, Terminal Care
Abstract

Purpose: The authors performed a structured literature review to understand residents' experiences with end-of-life (EOL) decision making with adult hospitalized patients, specifically regarding decisions to withhold or withdraw advanced life-support measures., Method: An Ovid-based strategy was used to search Medline, ERIC, PsychINFO, and CINHAL databases for articles published between 1966 and February 2005, combining the domains of "resuscitation orders," "decision making," and "internship and residency." All quantitative and qualitative studies examining residents' EOL decision making with adult hospitalized patients were included. The authors developed and applied a scoring system for relevance and quality, performed data abstraction and quality assessment independently and in duplicate, then met to collate findings and identify factors in residents' EOL decision making., Results: The searches yielded 884 articles, of which 26 were included. Variable methodologies precluded meta-analysis. In these studies, residents felt unprepared to handle patient EOL decision making, although exposure to EOL discussions helped them gain confidence. Residents' attitudes, skills, and knowledge were key determinants of whether EOL decisions were addressed. Many misinterpreted the terms "DNR" and "futility." Residents' understanding of the patient EOL decision-making process could be extremely variable, and their do-not-resuscitate discussions suboptimal. Residents' lived practice experience of the patient EOL decision-making process was often at odds with what they were taught in formal curricula., Conclusions: Educational strategies aimed at changing residents' knowledge, skills and attitude should address the hidden curriculum for the patient EOL decision-making process that is part of the experienced culture of every day practice. Future studies of this experienced culture would inform specific educational interventions.

Published
2005
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