Search

Your search keyword '"Agoston, Gergely"' showing total 39 results
Start Over Author "Agoston, Gergely"
39 results on '"Agoston, Gergely"'

1. Left atrial function during exercise stress echocardiography as a sign of paroxysmal/persistent atrial fibrillation

Author

Zagatina, Angela, Ciampi, Quirino, Peteiro, Jesus Vazquez, Kalinina, Elena, Begidova, Irina, Padang, Ratnasari, Boshchenko, Alla, Merli, Elisa, Lisi, Matteo, Rodriguez-Zanella, Hugo, Kobal, Sergio, Agoston, Gergely, Varga, Albert, Wierzbowska-Drabik, Karina, Kasprzak, Jarosław D., Arbucci, Rosina, Zhuravleva, Olga, Čelutkienė, Jelena, Lowenstein, Jorge, Ratanasit, Nithima Chaowalit, Colonna, Paolo, Carerj, Scipione, Pepi, Mauro, Pellikka, Patricia A., and Picano, Eugenio

Published
2024
Full Text
View/download PDF

3. Age-changes in right ventricular function–pulmonary circulation coupling: from pediatric to adult stage in 1899 healthy subjects. The RIGHT Heart International NETwork (RIGHT-NET)

Author

Vriz, Olga, Veldman, Gruschen, Gargani, Luna, Ferrara, Francesco, Frumento, Paolo, D’Alto, Michele, D’Andrea, Antonello, Radaan, Sarah Aldosari, Cocchia, Rosangela, Marra, Alberto Maria, Ranieri, Brigida, Salzano, Andrea, Stanziola, Anna Agnese, Voilliot, Damien, Agoston, Gergely, Cademartiri, Filippo, Cittadini, Antonio, Kasprzak, Jaroslaw D., Grünig, Ekkehard, Bandera, Francesco, Guazzi, Marco, Rudski, Lawrence, and Bossone, Eduardo

Published
2021
Full Text
View/download PDF

5. Prognostic Value of Lung Ultrasound B-Lines in Systemic Sclerosis

Author

Gargani, Luna, Bruni, Cosimo, Romei, Chiara, Frumento, Paolo, Moreo, Antonella, Agoston, Gergely, Guiducci, Serena, Bellando-Randone, Silvia, Lepri, Gemma, Belloli, Laura, Della Rossa, Alessandra, Delle Sedie, Andrea, Stagnaro, Chiara, De Nes, Michele, Salvadori, Stefano, Mosca, Marta, Falaschi, Fabio, Epis, Oscar, Picano, Eugenio, and Matucci-Cerinic, Marco

Published
2020
Full Text
View/download PDF

6. Pulmonary Congestion During Exercise Stress Echocardiography in Ischemic and Heart Failure Patients

Author

Merli, Elisa, Ciampi, Quirino, Scali, Maria Chiara, Zagatina, Angela, Merlo, Pablo Martin, Arbucci, Rosina, Daros, Clarissa Borguezan, de Castro e Silva Pretto, José Luis, Amor, Miguel, Salamè, Michael F., Mosto, Hugo, Morrone, Doralisa, D’Andrea, Antonello, Reisenhofer, Barbara, Rodriguez-Zanella, Hugo, Wierzbowska-Drabik, Karina, Kasprzak, Jaroslaw D., Agoston, Gergely, Varga, Albert, Lowenstein, Jorge, Dodi, Claudio, Cortigiani, Lauro, Simova, Iana, Samardjieva, Martina, Citro, Rodolfo, Celutkiene, Jelena, Re, Federica, Monte, Ines, Gligorova, Suzana, Antonini-Canterin, Francesco, Pepi, Mauro, Carpeggiani, Clara, Pellikka, Patricia A., and Picano, Eugenio

Published
2022
Full Text
View/download PDF

7. Right Ventricular Functional Reserve in Early-Stage Idiopathic Pulmonary Fibrosis: An Exercise Two-Dimensional Speckle Tracking Doppler Echocardiography Study

Author

Bossone, Eduardo, Gargani, Luna, Naeije, Robert, Ferrara, Francesco, Armstrong, William F., Kolias, Theodore John, Caliendo, Luigi, Cocchia, Rosangela, Citro, Rodolfo, Bellino, Michele, Radano, Ilaria, Cittadini, Antonio, D’Alto, Michele, Argiento, Paola, D’Andrea, Antonello, Carbone, Andreina, Sperlongano, Simona, Dellegrottaglie, Santo, De Luca, Nicola, Grazia, Montuori Maria, Rozza, Francesco, Russo, Valentina, Di Salvo, Giovanni, Ghio, Stefano, Grunig, Ekkerard, Marra, Alberto, Guazzi, Marco, Bandera, Francesco, Labate, Valentina, La Gerche, André, Limongelli, Giuseppe, Pacileo, Giuseppe, Verrengia, Marina, Kasprzak, Jaroslaw D., Wierzbowska Drabik, Karina, Kovacs, Gabor, Lancellotti, Patrizio, Moreo, Antonella, Casadei, Francesca, De Chiara, Benedetta, Ostenfeld, Ellen, Pieri, Francesco, Pratali, Lorenza, Saggar, Rajan, Saggar, Rajeev, Selton-Suty, Christine, Huttin, Olivier, Venner, Clément, Serra, Walter, Stanziola, Anna, Martino, Maria, Caccavo, Giovanna, Szabó, István, Varga, Albert, Agoston, Gergely, Voilliot, Darmien, Vriz, Olga, Galzerano, Domenico, Scalese, Marco, Carannante, Luca, Stanziola, Anna Agnese, and Conte, Marianna

Published
2019
Full Text
View/download PDF

8. Exercise Stress Echocardiography of the Right Ventricle and Pulmonary Circulation

Author

Gargani, Luna, primary, Pugliese, Nicola Riccardo, additional, De Biase, Nicolò, additional, Mazzola, Matteo, additional, Agoston, Gergely, additional, Arcopinto, Michele, additional, Argiento, Paola, additional, Armstrong, William F., additional, Bandera, Francesco, additional, Cademartiri, Filippo, additional, Carbone, Andreina, additional, Castaldo, Rossana, additional, Citro, Rodolfo, additional, Cocchia, Rosangela, additional, Codullo, Veronica, additional, D’Alto, Michele, additional, D'Andrea, Antonello, additional, Douschan, Philipp, additional, Fabiani, Iacopo, additional, Ferrara, Francesco, additional, Franzese, Monica, additional, Frumento, Paolo, additional, Ghio, Stefano, additional, Grünig, Ekkehard, additional, Guazzi, Marco, additional, Kasprzak, Jaroslaw D., additional, Kolias, Theodore, additional, Kovacs, Gabor, additional, La Gerche, André, additional, Limogelli, Giuseppe, additional, Marra, Alberto Maria, additional, Matucci-Cerinic, Marco, additional, Mauro, Ciro, additional, Moreo, Antonella, additional, Pratali, Lorenza, additional, Ranieri, Brigida, additional, Rega, Salvatore, additional, Rudski, Lawrence, additional, Saggar, Rajan, additional, Salzano, Andrea, additional, Serra, Walter, additional, Stanziola, Anna A., additional, Vannan, Mani A., additional, Voilliot, Damien, additional, Vriz, Olga, additional, Wierzbowska-Drabik, Karina, additional, Cittadini, Antonio, additional, Naeije, Robert, additional, Bossone, Eduardo, additional, Gargani, Luna, additional, Kolias, Theodore John, additional, Capone, Valentina, additional, Sepe, Chiara, additional, Capuano, Francesco, additional, Benvenga, Rossella, additional, Bellino, Michele, additional, Iuliano, Giuseppe, additional, Migliarino, Serena, additional, Radano, Ilaria, additional, Marra, Alberto, additional, Crisci, Giulia, additional, D’Assante, Roberta, additional, De Luca, Mariarosaria, additional, Giardino, Federica, additional, Rainone, Carmen, additional, Valente, Valeria, additional, D’Andrea, Antonello, additional, Russo, Valentina, additional, Dellegrottaglie, Santo, additional, Di Salvo, Giovanni, additional, Guida, Stefania, additional, Grunig, Ekkerard, additional, Eichstaedt, Christina A., additional, Labate, Valentina, additional, La Gerch, André, additional, Limongelli, Giuseppe, additional, Pacileo, Giuseppe, additional, Verrengia, Marina, additional, Casadei, Francesca, additional, De Chiara, Benedetta, additional, Ostenfeld, Ellen, additional, Pedrizzetti, Gianni, additional, Pieri, Francesco, additional, Mori, Fabio, additional, Moggi-Pignone, Alberto, additional, Raciti, Mauro, additional, Pugliese, Nicola, additional, D’Angelo, Gennaro, additional, Stanziola, Anna Agnese, additional, Rossella, D’Angelo, additional, Gallotta, Lorena, additional, Szabó, István, additional, Varga, Albert, additional, Galzerano, Domenico, additional, Vannan, Mani, additional, Mobasseri, Sara, additional, Flueckiger, Peter, additional, and Liu, Shizhen, additional

Published
2023
Full Text
View/download PDF

9. The Right Heart International Network (RIGHT-NET): Rationale, Objectives, Methodology, and Clinical Implications

Author

Ferrara, Francesco, Gargani, Luna, Armstrong, William F., Agoston, Gergely, Cittadini, Antonio, Citro, Rodolfo, D’Alto, Michele, D’Andrea, Antonello, Dellegrottaglie, Santo, De Luca, Nicola, Di Salvo, Giovanni, Ghio, Stefano, Grünig, Ekkehard, Guazzi, Marco, Kasprzak, Jaroslaw D., Kolias, Theodore John, Kovacs, Gabor, Lancellotti, Patrizio, La Gerche, Andrè, Limongelli, Giuseppe, Marra, Alberto Maria, Moreo, Antonella, Ostenfeld, Ellen, Pieri, Francesco, Pratali, Lorenza, Rudski, Lawrence G., Saggar, Rajan, Saggar, Rajeev, Scalese, Marco, Selton-Suty, Christine, Serra, Walter, Stanziola, Anna Agnese, Voilliot, Damien, Vriz, Olga, Naeije, Robert, and Bossone, Eduardo

Published
2018
Full Text
View/download PDF

11. Playing on distance: a relational rhetorical analysis of Viktor Orbán's Euroscepticism

Author

Agoston, Gergely

Abstract

ABSTRACTViktor Orbán has been a key figure in increasing the role Euroscepticism plays in European integration. By developing a new relational approach to rhetorical political analysis, this article examines how Orbán uses Eurosceptic rhetoric to move the largely pro-EU Hungarian public towards an EU-critical position. By analysing the Hungarian Prime Minister's speeches and interviews, it identifies three strategies of Eurosceptic positioning, political, cultural, and democratic, by which Orbán strategically creates distance between the EU and Hungarian voters regarding the EU's migration policy. Orbán's dynamic positioning expressed through his Eurosceptic rhetoric allows him to be pro- and anti-integrationist simultaneously.

Published
2024
Full Text
View/download PDF

12. B-lines with Lung Ultrasound: The Optimal Scan Technique at Rest and During Stress

Author

Picano, Eugenio, Ciampi, Quirino, Citro, Rodolfo, D'Andrea, Antonello, Scali, Maria Chiara, Cortigiani, Lauro, Olivotto, Iacopo, Mori, Fabio, Galderisi, Maurizio, Costantino, Marco Fabio, Pratali, Lorenza, di Salvo, Giovanni, Bossone, Eduardo, Ferrara, Francesco, Kasprszak, Jaroslaw D., Rigo, Fausto, Gaibazzi, Nicola, Limongelli, Giuseppe, Pacileo, Giuseppe, Severino, Sergio, Pinamonti, Bruno, Massa, Laura, Torres, Marco A.R., Miglioranza, Marcelo H., Daros, Clarissa Borguezan, Luis de Castro e Silva Pretto, José, Djordjevic-Dikic, Ana, Dekleva, Milica, Varga, Albert, Agoston, Gergely, Palinkas, Attila, Zagatina, Angela, Simova, Iana, Amor, Miguel, Lowenstein, Jorge, Merlo, Pablo, Celutkiene, Jelena, Perez, Julio E., Trambaiolo, Paolo, Gregori, Dario, Colonna, Paolo, Andreassi, Maria Grazia, De Nes, Michele, Arystan, Ayana, Paterni, Marco, Carpeggiani, Clara, Zhuravskaya, Nadezhda, and Marzilli, Mario

Published
2017
Full Text
View/download PDF

13. Left atrial volume changes during exercise stress echocardiography in heart failure and hypertrophic cardiomyopathy

Author

Wierzbowska-Drabik, Karina, primary, Kasprzak, Jarosław D., additional, Haberka, Maciej, additional, Peteiro, Jesus, additional, Re, Federica, additional, D'Alfonso, Maria Grazia, additional, Mori, Fabio, additional, Palinkas, Eszter D., additional, Agoston, Gergely, additional, Varga, Albert, additional, Djordjevic-Dikic, Ana, additional, Tesic, Milorad, additional, Zagatina, Angela, additional, Rodriguez-Zanella, Hugo, additional, Simova, Iana, additional, Merli, Elisa, additional, Morrone, Doralisa, additional, D'Andrea, Antonello, additional, Camarozano, Ana C., additional, Reisenhofer, Barbara, additional, Prota, Costantina, additional, Citro, Rodolfo, additional, Celutkiene, Jelena, additional, Boshchenko, Alla, additional, Ciampi, Quirino, additional, and Picano, Eugenio, additional

Published
2022
Full Text
View/download PDF

14. Heart failure 2019. Insights from the National Society of Cardiology Journals

Author

Gatzov, Plamen, primary, Monsuez, Jean-Jacques, additional, Agoston, Gergely, additional, Aschermann, Michael, additional, Mahfouz Badran, Hala, additional, Cohen, Ariel, additional, Huber, Kurt, additional, Shlyakhto, Evgeny, additional, Ural, Dilek, additional, Ferreira-González, and, Ignacio, additional, and Alfonso, Fernando, additional

Published
2021
Full Text
View/download PDF

16. Insuficiencia cardiaca 2019. Reflexiones de las Revistas de las Sociedades Nacionales de Cardiología

Author

Gatzov, Plamen, Monsuez, Jean-Jacques, Agoston, Gergely, Aschermann, Michael, Badran, Hala Mahfouz, Cohen, Ariel, Huber, Kurt, Shlyakhto, Evgeny, Ural, Dilek, Alfonso Manterola, Fernando, Ferreira González, Ignacio, Gatzov, Plamen, Monsuez, Jean-Jacques, Agoston, Gergely, Aschermann, Michael, Badran, Hala Mahfouz, Cohen, Ariel, Huber, Kurt, Shlyakhto, Evgeny, Ural, Dilek, Alfonso Manterola, Fernando, and Ferreira González, Ignacio

Published
2021

17. Stress Echo 2030: The Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging

Author

Picano, Eugenio, Ciampi, Quirino, Cortigiani, Lauro, Arruda-Olson, Adelaide M., Borguezan-Daros, Clarissa, Silva Pretto, José Luis de Castro, Cocchia, Rosangela, Bossone, Eduardo, Merli, Elisa, Kane, Garvan C., Varga, Albert, Agoston, Gergely, Scali, Maria Chiara, Morrone, Doralisa, Simova, Iana, Samardjieva, Martina, Boschenko, Alla, Ryabova, Tamara, Vrublevsky, Alexander, Palinkas, Attila, Palinkas, Eszter D., Sepp, Robert, Torres, Marco A.R., Villarraga, Hector R., Kovacevic Preradovic, Tamara, Citro, Rodolfo, Amor, Miguel, Mosto, Hugo, Salamè, Michael, Leeson, Paul, Mangia, Cristina, Gaibazzi, Nicola, Tuttolomondo, Domenico, Prota, Constantina, Peteiro-Vázquez, Jesús, Van de Heyning, Caroline M., D'Andrea, Antonello, Rigo, Fausto, Nikolic, Aleksandra, Ostojic, Miodrag, Lowenstein, Jorge, Arbucci, Rosina, Lowenstein Haber, Diego M., Merlo, Pablo M., Wierzbowska-Drabik, Karina, Kasprzak, Jaroslaw D., Haberka, Maciej, Camarozano, Ana Cristina, Ratanasit, Nithima, Mori, Fabio, D'Alfonso, Maria Grazia, Tassetti, Luigi, Milazzo, Alessandra, Olivotto, Iacopo, Marchi, Alberto, Rodríguez-Zanella, Hugo, Zagatina, Angela, Padang, Ratnasari, Dekleva, Milica, Djordievic-Dikic, Ana, Boskovic, Nikola, Tesic, Milorad, Giga, Vojislav, Belesin, Branko, Di Salvo, Giovanni, Lorenzoni, Valentina, Cameli, Matteo, Mandoli, Giulia Elena, Bombardini, Tonino, Caso, Pio, Celutkiene, Jelena, Barbieri, Andrea, Benfari, Giovanni, Bartolacelli, Ylenia, Malagoli, Alessandro, Bursi, Francesca, Mantovani, Francesca, Villari, Bruno, Russo, Antonello, De Nes, Michelle, Carpeggiani, Clara, Monte, Ines, Re, Federica, Cotrim, Carlos, Bilardo, Giuseppe, Saad, Ariel K., Karuzas, Arnas, Matuliauskas, Dovydas, Colonna, Paolo, Antonini-Canterin, Francesco, Pepi, Mauro, Pellikka, Patricia A., Picano, Eugenio, Ciampi, Quirino, Cortigiani, Lauro, Arruda-Olson, Adelaide M., Borguezan-Daros, Clarissa, Silva Pretto, José Luis de Castro, Cocchia, Rosangela, Bossone, Eduardo, Merli, Elisa, Kane, Garvan C., Varga, Albert, Agoston, Gergely, Scali, Maria Chiara, Morrone, Doralisa, Simova, Iana, Samardjieva, Martina, Boschenko, Alla, Ryabova, Tamara, Vrublevsky, Alexander, Palinkas, Attila, Palinkas, Eszter D., Sepp, Robert, Torres, Marco A.R., Villarraga, Hector R., Kovacevic Preradovic, Tamara, Citro, Rodolfo, Amor, Miguel, Mosto, Hugo, Salamè, Michael, Leeson, Paul, Mangia, Cristina, Gaibazzi, Nicola, Tuttolomondo, Domenico, Prota, Constantina, Peteiro-Vázquez, Jesús, Van de Heyning, Caroline M., D'Andrea, Antonello, Rigo, Fausto, Nikolic, Aleksandra, Ostojic, Miodrag, Lowenstein, Jorge, Arbucci, Rosina, Lowenstein Haber, Diego M., Merlo, Pablo M., Wierzbowska-Drabik, Karina, Kasprzak, Jaroslaw D., Haberka, Maciej, Camarozano, Ana Cristina, Ratanasit, Nithima, Mori, Fabio, D'Alfonso, Maria Grazia, Tassetti, Luigi, Milazzo, Alessandra, Olivotto, Iacopo, Marchi, Alberto, Rodríguez-Zanella, Hugo, Zagatina, Angela, Padang, Ratnasari, Dekleva, Milica, Djordievic-Dikic, Ana, Boskovic, Nikola, Tesic, Milorad, Giga, Vojislav, Belesin, Branko, Di Salvo, Giovanni, Lorenzoni, Valentina, Cameli, Matteo, Mandoli, Giulia Elena, Bombardini, Tonino, Caso, Pio, Celutkiene, Jelena, Barbieri, Andrea, Benfari, Giovanni, Bartolacelli, Ylenia, Malagoli, Alessandro, Bursi, Francesca, Mantovani, Francesca, Villari, Bruno, Russo, Antonello, De Nes, Michelle, Carpeggiani, Clara, Monte, Ines, Re, Federica, Cotrim, Carlos, Bilardo, Giuseppe, Saad, Ariel K., Karuzas, Arnas, Matuliauskas, Dovydas, Colonna, Paolo, Antonini-Canterin, Francesco, Pepi, Mauro, and Pellikka, Patricia A.

Abstract

[Abstract] With stress echo (SE) 2020 study, a new standard of practice in stress imaging was developed and disseminated: the ABCDE protocol for functional testing within and beyond CAD. ABCDE protocol was the fruit of SE 2020, and is the seed of SE 2030, which is articulated in 12 projects: 1-SE in coronary artery disease (SECAD); 2-SE in diastolic heart failure (SEDIA); 3-SE in hypertrophic cardiomyopathy (SEHCA); 4-SE post-chest radiotherapy and chemotherapy (SERA); 5-Artificial intelligence SE evaluation (AI-SEE); 6-Environmental stress echocardiography and air pollution (ESTER); 7-SE in repaired Tetralogy of Fallot (SETOF); 8-SE in post-COVID-19 (SECOV); 9: Recovery by stress echo of conventionally unfit donor good hearts (RESURGE); 10-SE for mitral ischemic regurgitation (SEMIR); 11-SE in valvular heart disease (SEVA); 12-SE for coronary vasospasm (SESPASM). The study aims to recruit in the next 5 years (2021-2025) ≥10,000 patients followed for ≥5 years (up to 2030) from ≥20 quality-controlled laboratories from ≥10 countries. In this COVID-19 era of sustainable health care delivery, SE2030 will provide the evidence to finally recommend SE as the optimal and versatile imaging modality for functional testing anywhere, any time, and in any patient.

Published
2021

18. Right Ventricular Functional Reserve in Early-Stage Idiopathic Pulmonary Fibrosis: An Exercise Two-Dimensional Speckle Tracking Doppler Echocardiography Study

Author

D'Andrea, Antonello, Stanziola, Anna Agnese, Saggar, Rajan, Saggar, Rajeev, Sperlongano, Simona, Conte, Marianna, D'Alto, Michele, Ferrara, Francesco, Gargani, Luna, Lancellotti, Patrizio, Bossone, Eduardo, Naeije, Robert, Armstrong, William F., Kolias, Theodore John, Caliendo, Luigi, Cocchia, Rosangela, Citro, Rodolfo, Bellino, Michele, Radano, Ilaria, Cittadini, Antonio, Argiento, Paola, Carbone, Andreina, Dellegrottaglie, Santo, De Luca, Nicola, Grazia, Montuori Maria, Rozza, Francesco, Russo, Valentina, Di Salvo, Giovanni, Ghio, Stefano, Grunig, Ekkerard, Marra, Alberto, Guazzi, Marco, Bandera, Francesco, Labate, Valentina, La Gerche, André, Limongelli, Giuseppe, Pacileo, Giuseppe, Verrengia, Marina, Kasprzak, Jaroslaw D., Wierzbowska Drabik, Karina, Kovacs, Gabor, Moreo, Antonella, Casadei, Francesca, De Chiara, Benedetta, Ostenfeld, Ellen, Pieri, Francesco, Pratali, Lorenza, Selton-Suty, Christine, Huttin, Olivier, Venner, Clément, Serra, Walter, Stanziola, Anna, DI MARTINO, Maria Consiglia, Caccavo, Giovanna, Szabó, István, Varga, Albert, Agoston, Gergely, Voilliot, Darmien, Vriz, Olga, Galzerano, Domenico, Scalese, Marco, Carannante, Luca, D'Andrea, A., Stanziola, A. A., Saggar, R., Sperlongano, S., Conte, M., D'Alto, M., Ferrara, F., Gargani, L., Lancellotti, P., Bossone, E., Naeije, R., Armstrong, W. F., Kolias, T. J., Caliendo, L., Cocchia, R., Citro, R., Bellino, M., Radano, Flora, Cittadini, A., Argiento, P., Carbone, A., Dellegrottaglie, S., De Luca, N., Grazia, M. M., Rozza, F., Russo, V., Di Salvo, G., Ghio, S., Grunig, E., Marra, A., Guazzi, M., Bandera, F., Labate, V., La Gerche, A., Limongelli, G., Pacileo, G., Verrengia, Valentina, Kasprzak, J. D., Wierzbowska Drabik, K., Kovacs, G., Moreo, A., Casadei, F., De Chiara, B., Ostenfeld, E., Pieri, F., Pratali, L., Selton-Suty, C., Huttin, O., Venner, C., Serra, W., Stanziola, A., Martino, M., Caccavo, Giovanna, Szabo, I., Varga, A., Agoston, G., Voilliot, D., Vriz, O., Galzerano, D., Scalese, M., Carannante, L., D'Andrea, Antonello, Stanziola, Anna Agnese, Saggar, Rajan, Saggar, Rajeev, Sperlongano, Simona, Conte, Marianna, D'Alto, Michele, Ferrara, Francesco, Gargani, Luna, Lancellotti, Patrizio, Bossone, Eduardo, Naeije, Robert, Armstrong, William F., Kolias, Theodore John, Caliendo, Luigi, Cocchia, Rosangela, Citro, Rodolfo, Bellino, Michele, Radano, Ilaria, Cittadini, Antonio, Argiento, Paola, Carbone, Andreina, Dellegrottaglie, Santo, De Luca, Nicola, Grazia, Montuori Maria, Rozza, Francesco, Russo, Valentina, Di Salvo, Giovanni, Ghio, Stefano, Grunig, Ekkerard, Marra, Alberto, Guazzi, Marco, Bandera, Francesco, Labate, Valentina, La Gerche, André, Limongelli, Giuseppe, Pacileo, Giuseppe, Verrengia, Marina, Kasprzak, Jaroslaw D., Wierzbowska Drabik, Karina, Kovacs, Gabor, Moreo, Antonella, Casadei, Francesca, De Chiara, Benedetta, Ostenfeld, Ellen, Pieri, Francesco, Pratali, Lorenza, Selton-Suty, Christine, Huttin, Olivier, Venner, Clément, Serra, Walter, Stanziola, Anna, DI MARTINO, Maria Consiglia, Szabó, István, Varga, Albert, Agoston, Gergely, Voilliot, Darmien, Vriz, Olga, Galzerano, Domenico, Scalese, Marco, and Carannante, Luca

Subjects
Adult, Male, Functional Residual Capacity, Physiological, Hypertension, Pulmonary, Ventricular Dysfunction, Right, stress echocardiography, Kaplan-Meier Estimate, right ventricle, Stress, Risk Assessment, Severity of Illness Index, Computer-Assisted, Image Interpretation, Computer-Assisted, Ventricular Dysfunction, Humans, Adaptation, Image Interpretation, Proportional Hazards Models, idiopathic pulmonary fibrosi, 2D speckle tracking echocardiography, idiopathic pulmonary fibrosis, Adaptation, Physiological, Blood Gas Analysis, Case-Control Studies, Disease Progression, Echocardiography, Doppler, Echocardiography, Stress, Female, Hemodynamics, Idiopathic Pulmonary Fibrosis, Italy, Middle Aged, Prognosis, Survival Analysis, Vascular Resistance, Doppler, Pulmonary, Right, Echocardiography, Hypertension
Abstract

BRACKGROUND: The most important determinant of long-term survival in patients with idiopathic pulmonary fibrosis is the right ventricular (RV) adaptation to the increased pulmonary vascular resistance. Our aim was to explore RV contractile reserve during stress echocardiography in early-stage IPF.METHOD: Fifty early-stage patients with IPF and 50 healthy control patients underwent rest and stress echocardiography, including RV two-dimensional speckle tracking echocardiography. At peak exertion, blood gas analysis and spirometry were also assessed.RESULTS: At rest, RV diameters were mildly increased in IPF; however, although RV conventional systolic function indexes were similar between the IPF and control groups, RV global longitudinal strain and RV lateral wall longitudinal strain (LWLS) were significantly reduced in the IPF cohort. During physical exercise, patients with IPF showed a reduced exercise tolerance with lower maximal workload (P < .01), level of oxygen saturation (P < .001), and peak heart rate (P < .01). Systolic and diastolic BP values were similar in both groups. Systolic pulmonary artery pressure (PAPs) increase (Delta PAPs) during exertion was higher in IPF vs healthy subjects (P < .0001); RV LWLS increase (Delta RV LWLS) during exercise was lower in patients with IPF vs control patients (P < .00001). By multivariable analysis, RV LWLS at rest and Delta RV LWLS were directly related to peak exertion capacity, PAPs, and blood oxygen saturation level (Spo(2) ; P < .0001). Delta RV LWLS was directly related to diffusion lung carbon monoxide (P < .0001).CONCLUSION RV myocardial dysfunction is already present at rest in early-stage IPF and worsens during exertion as detected by two-dimensional speckle-tracking echocardiography. The RV altered contractile reserve appears to be related to reduced exercise tolerability and impaired pulmonary hemodynamic.

Published
2019

20. Clinical and echocardiographic correlations of exercise-induced pulmonary hypertension in systemic sclerosis: A multicenter study

Author

Gargani, Luna, Pignone, Alberto, Agoston, Gergely, Moreo, Antonella, Capati, Eugenia, Badano, Luigi P., Doveri, Marica, Bazzichi, Laura, Costantino, Marco Fabio, Pavellini, Andrea, Pieri, Francesco, Musca, Francesco, Muraru, Denisa, Epis, Oscar, Bruschi, Eleonora, De Chiara, Benedetta, Perfetto, Federico, Mori, Fabio, Parodi, Oberdan, Sicari, Rosa, Bombardieri, Stefano, Varga, Albert, Cerinic, Marco Matucci, Bossone, Eduardo, and Picano, Eugenio

Published
2013
Full Text
View/download PDF

21. Stress echo in Italy

Author

Ciampi, Quirino, Citro, Rodolfo, Severino, Sergio, Labanti, Graziana, Cortigiani, Lauro, Sicari, Rosa, Gaibazzi, Nicola, Galderisi, Maurizio, Bossone, Eduardo, Colonna, Paolo, Picano, Eugenio, D'Andrea, Antonello, Scali, Maria Chiara, Olivotto, Iacopo, Mori, Fabio, Costantino, Marco Fabio, Pratali, Lorenza, Di Salvo, Giovanni, Ferrara, Francesco, Gargani, Luna, Rigo, Fausto, Limongelli, Giuseppe, Pacileo, Giuseppe, Andreassi, Maria Grazia, Pinamonti, Bruno, Massa, Laura, Torres, Marco A. R., Miglioranza, Marcelo H., Daros, Clarissa Borguezan, De Castro E Silva Pretto, José Luis, Beleslin, Branko, Djordjevic-DIkic, Ana, Varga, Albert, Palinkas, Attila, Agoston, Gergely, Gregori, Dario, Trambaiolo, Paolo, Arystan, Ayana, Paterni, Marco, Carpeggiani, Clara, Ciampi, Quirino, Citro, Rodolfo, Severino, Sergio, Labanti, Graziana, Cortigiani, Lauro, Sicari, Rosa, Gaibazzi, Nicola, Galderisi, Maurizio, Bossone, Eduardo, Colonna, Paolo, Picano, Eugenio, D'Andrea, Antonello, Scali, Maria Chiara, Olivotto, Iacopo, Mori, Fabio, Costantino, Marco Fabio, Pratali, Lorenza, Di Salvo, Giovanni, Ferrara, Francesco, Gargani, Luna, Rigo, Fausto, Limongelli, Giuseppe, Pacileo, Giuseppe, Andreassi, Maria Grazia, Pinamonti, Bruno, Massa, Laura, Torres, Marco A. R., Miglioranza, Marcelo H., Daros, Clarissa Borguezan, De Castro E Silva Pretto, José Lui, Beleslin, Branko, Djordjevic-DIkic, Ana, Varga, Albert, Palinkas, Attila, Agoston, Gergely, Gregori, Dario, Trambaiolo, Paolo, Arystan, Ayana, Paterni, Marco, and Carpeggiani, Clara

Subjects
medicine.medical_specialty, business.industry, Myocardial Ischemia, MEDLINE, General Medicine, 030204 cardiovascular system & hematology, Stress, Echocardiography, Stress, Humans, Italy, Practice Guidelines as Topic, Societies, Medical, Cardiology and Cardiovascular Medicine, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, Echocardiography, Stress Echo, Medical, Medicine, 030212 general & internal medicine, State (computer science), Societies, business
Published
2017

22. Heart Failure 2019

Author

Gatzov, Plamen, primary, Monsuez, Jean-Jacques, additional, Agoston, Gergely, additional, Aschermann, Michael, additional, Badran, Hala Mahfouz, additional, Cohen, Ariel, additional, Huber, Kurt, additional, Shlyakhto, Evgeny, additional, Ural, Dilek, additional, Ferreira-Gonzalez, Ignacio, additional, and Alfonso, Fernando, additional

Published
2020
Full Text
View/download PDF

23. Lung Ultrasound and Pulmonary Congestion During Stress Echocardiography

Author

Scali, Maria Chiara, primary, Zagatina, Angela, additional, Ciampi, Quirino, additional, Cortigiani, Lauro, additional, D'Andrea, Antonello, additional, Daros, Clarissa Borguezan, additional, Zhuravskaya, Nadezhda, additional, Kasprzak, Jaroslaw D., additional, Wierzbowska-Drabik, Karina, additional, Luis de Castro e Silva Pretto, José, additional, Djordjevic-Dikic, Ana, additional, Beleslin, Branko, additional, Petrovic, Marija, additional, Boskovic, Nikola, additional, Tesic, Milorad, additional, Monte, Ines, additional, Simova, Iana, additional, Vladova, Martina, additional, Boshchenko, Alla, additional, Vrublevsky, Alexander, additional, Citro, Rodolfo, additional, Amor, Miguel, additional, Vargas Mieles, Paul E., additional, Arbucci, Rosina, additional, Merlo, Pablo Martin, additional, Lowenstein Haber, Diego M., additional, Dodi, Claudio, additional, Rigo, Fausto, additional, Gligorova, Suzana, additional, Dekleva, Milica, additional, Severino, Sergio, additional, Lattanzi, Fabio, additional, Morrone, Doralisa, additional, Galderisi, Maurizio, additional, Torres, Marco A.R., additional, Salustri, Alessandro, additional, Rodrìguez-Zanella, Hugo, additional, Costantino, Fabio Marco, additional, Varga, Albert, additional, Agoston, Gergely, additional, Bossone, Eduardo, additional, Ferrara, Francesco, additional, Gaibazzi, Nicola, additional, Celutkiene, Jelena, additional, Haberka, Maciej, additional, Mori, Fabio, additional, D'Alfonso, Maria Grazia, additional, Reisenhofer, Barbara, additional, Camarozano, Ana Cristina, additional, Miglioranza, Marcelo Haertel, additional, Szymczyk, Ewa, additional, Wejner-Mik, Paulina, additional, Wdowiak-Okrojek, Katarzyna, additional, Preradovic-Kovacevic, Tamara, additional, Bombardini, Tonino, additional, Ostojic, Miodrag, additional, Nikolic, Aleksandra, additional, Re, Federica, additional, Barbieri, Andrea, additional, Di Salvo, Giovanni, additional, Merli, Elisa, additional, Colonna, Paolo, additional, Lorenzoni, Valentina, additional, De Nes, Michele, additional, Paterni, Marco, additional, Carpeggiani, Clara, additional, Lowenstein, Jorge, additional, and Picano, Eugenio, additional

Published
2020
Full Text
View/download PDF

24. A multicentric quality-control study of exercise Doppler echocardiography of the right heart and the pulmonary circulation

Author

Ferrara, Francesco, primary, Gargani, Luna, additional, Contaldi, Carla, additional, Agoston, Gergely, additional, Argiento, Paola, additional, Armstrong, William, additional, Citro, Rodolfo, additional, Cittadini, Antonio, additional, Cocchia, Rosangela, additional, Alto, Michele D, additional, Andrea, Antonello D, additional, Douschan, Philippe, additional, Ghio, Stefano, additional, nig, Ekkehard Gr, additional, Guazzi, Marco, additional, Kasprzak, Jaroslaw, additional, Kolias, Theodore, additional, Marra, Alberto, additional, Moreo, Antonella, additional, Pieri, Francesco, additional, Pratali, Lorenza, additional, Ranieri, Brigida, additional, Rudski, Lawrence, additional, Russo, Valentina, additional, Saggar, Rajan, additional, Stanziola, Anna Agnese, additional, Vannan, Mani A, additional, Vriz, Olga, additional, Naeije, Robert, additional, and Bossone, Eduardo, additional

Published
2020
Full Text
View/download PDF

25. Sensory neuropathy affects cardiac miRNA expression network targeting IGF-1, SLC2a-12, EIF-4e, and ULK-2 mRNAs

Author

Bencsik, Péter, Kiss, Krisztina, Ágg, Bence, Baán, Júlia A., Agoston, Gergely, Varga, Albert, Gömöri, Kamilla, Mendler, Luca, Faragó, Nóra, Zvara, Ágnes, Sántha, Péter, Puskás, László G., Jancsó, Gábor, Ferdinandy, Peter, Bencsik, Péter, Kiss, Krisztina, Ágg, Bence, Baán, Júlia A., Agoston, Gergely, Varga, Albert, Gömöri, Kamilla, Mendler, Luca, Faragó, Nóra, Zvara, Ágnes, Sántha, Péter, Puskás, László G., Jancsó, Gábor, and Ferdinandy, Peter

Abstract

Background: Here we examined myocardial microRNA (miRNA) expression profile in a sensory neuropathy model with cardiac diastolic dysfunction and aimed to identify key mRNA molecular targets of the differentially expressed miRNAs that may contribute to cardiac dysfunction. Methods: Male Wistar rats were treated with vehicle or capsaicin for 3 days to induce systemic sensory neuropathy. Seven days later, diastolic dysfunction was detected by echocardiography, and miRNAs were isolated from the whole ventricles. Results: Out of 711 known miRNAs measured by miRNA microarray, the expression of 257 miRNAs was detected in the heart. As compared to vehicle-treated hearts, miR-344b, miR-466b, miR-98, let-7a, miR-1, miR-206, and miR-34b were downregulated, while miR-181a was upregulated as validated also by quantitative real time polymerase chain reaction (qRT-PCR). By an in silico network analysis, we identified common mRNA targets (insulin-like growth factor 1 (IGF-1), solute carrier family 2 facilitated glucose transporter member 12 (SLC2a-12), eukaryotic translation initiation factor 4e (EIF-4e), and Unc-51 like autophagy activating kinase 2 (ULK-2)) targeted by at least three altered miRNAs. Predicted upregulation of these mRNA targets were validated by qRT-PCR. Conclusion: This is the first demonstration that sensory neuropathy affects cardiac miRNA expression network targeting IGF-1, SLC2a-12, EIF-4e, and ULK-2, which may contribute to cardiac diastolic dysfunction. These results further support the need for unbiased omics approach followed by in silico prediction and validation of molecular targets to reveal novel pathomechanisms.

Published
2019

26. Right Ventricular Functional Reserve in Early-Stage Idiopathic Pulmonary Fibrosis

Author

D’Andrea, Antonello, primary, Stanziola, Anna Agnese, additional, Saggar, Rajan, additional, Saggar, Rajeev, additional, Sperlongano, Simona, additional, Conte, Marianna, additional, D’Alto, Michele, additional, Ferrara, Francesco, additional, Gargani, Luna, additional, Lancellotti, Patrizio, additional, Bossone, Eduardo, additional, Naeije, Robert, additional, Armstrong, William F., additional, Kolias, Theodore John, additional, Caliendo, Luigi, additional, Cocchia, Rosangela, additional, Citro, Rodolfo, additional, Bellino, Michele, additional, Radano, Ilaria, additional, Cittadini, Antonio, additional, Argiento, Paola, additional, D’Andrea, Antonello, additional, Carbone, Andreina, additional, Dellegrottaglie, Santo, additional, De Luca, Nicola, additional, Grazia, Montuori Maria, additional, Rozza, Francesco, additional, Russo, Valentina, additional, Di Salvo, Giovanni, additional, Ghio, Stefano, additional, Grunig, Ekkerard, additional, Marra, Alberto, additional, Guazzi, Marco, additional, Bandera, Francesco, additional, Labate, Valentina, additional, La Gerche, André, additional, Limongelli, Giuseppe, additional, Pacileo, Giuseppe, additional, Verrengia, Marina, additional, Kasprzak, Jaroslaw D., additional, Wierzbowska Drabik, Karina, additional, Kovacs, Gabor, additional, Moreo, Antonella, additional, Casadei, Francesca, additional, De Chiara, Benedetta, additional, Ostenfeld, Ellen, additional, Pieri, Francesco, additional, Pratali, Lorenza, additional, Selton-Suty, Christine, additional, Huttin, Olivier, additional, Venner, Clément, additional, Serra, Walter, additional, Stanziola, Anna, additional, Martino, Maria, additional, Caccavo, Giovanna, additional, Szabó, István, additional, Varga, Albert, additional, Agoston, Gergely, additional, Voilliot, Darmien, additional, Vriz, Olga, additional, Galzerano, Domenico, additional, Scalese, Marco, additional, and Carannante, Luca, additional

Published
2019
Full Text
View/download PDF

27. Feasibility and functional correlates of left atrial volume changes during stress echocardiography in chronic coronary syndromes.

Author

Morrone, Doralisa, Arbucci, Rosina, Wierzbowska-Drabik, Karina, Ciampi, Quirino, Peteiro, Jesus, Agoston, Gergely, Varga, Albert, Camarozano, Ana Cristina, Boshchenko, Alla, Ryabova, Tamara, Dekleva, Milica, Simova, Iana, Lowenstein Haber, Diego M., Tesic, Milorad, Boskovic, Nikola, Djordjevic-Dikic, Ana, Beleslin, Branko, D'Alfonso, Maria Grazia, Mori, Fabio, and Rodrìguez-Zanella, Hugo

Abstract

An enlarged left atrial volume index (LAVI) at rest mirrors increased LA pressure and/or impairment of LA function. A cardiovascular stress may acutely modify left atrial volume (LAV) within minutes. Aim of this study was to assess the feasibility and functional correlates of LAV-stress echocardiography (SE) Out of 514 subjects referred to 10 quality-controlled labs, LAV-SE was completed in 490 (359 male, age 67 ± 12 years) with suspected or known chronic coronary syndromes (n = 462) or asymptomatic controls (n = 28). The utilized stress was exercise in 177, vasodilator in 167, dobutamine in 146. LAV was measured with the biplane disk summation method. SE was performed with the ABCDE protocol. The intra-observer and inter-observer LAV variability were 5% and 8%, respectively. ∆-LAVI changes (stress-rest) were negatively correlated with resting LAVI (r = − 0.271, p < 0.001) and heart rate reserve (r = -.239, p < 0.001). LAV-dilators were defined as those with stress-rest increase ≥ 6.8 ml/m2, a cutoff derived from a calculated reference change value above the biological, analytical and observer variability of LAVI. LAV dilation occurred in 56 patients (11%), more frequently with exercise (16%) and dipyridamole (13%) compared to dobutamine (4%, p < 0.01). At multivariable logistic regression analysis, B-lines ≥ 2 (OR: 2.586, 95% CI = 1.1293–5.169, p = 0.007) and abnormal contractile reserve (OR: 2.207, 95% CI = 1.111–4.386, p = 0.024) were associated with LAV dilation. In conclusion, LAV-SE is feasible with high success rate and low variability in patients with chronic coronary syndromes. LAV dilation is more likely with reduced left ventricular contractile reserve and pulmonary congestion. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

28. The Right Heart International Network (RIGHT-NET): Rationale, Objectives, Methodology, and Clinical Implications

Author

Ferrara, F., Gargani, Luna, Armstrong, W.F., Agoston, Gergely, Cittadini, Antonio, Citro, Rodolfo, D'Alto, M., D'Andrea, A., Dellegrottaglie, Santo, De Luca, Nicola, Di Salvo, Giovanni, Ghio, S., Grünig, Ekkehard, Guazzi, Marco, Kasprzak, Joanna J.M., Kolias, Theodore John, Kovacs, Gabor, Lancellotti, Patrizio, La Gerche, André, Limongelli, Giuseppe, Marra, A.M., Moreo, Antonella, Ostenfeld, Ellen, Pieri, Francesco, Pratali, Lorenza, Rudski, Lawrence Glenn, Saggar, R., Scalese, Marco, Selton-Suty, Christine, Serra, Walter, Stanziola, Anna Agnese, Voilliot, Damien, Vriz, Olga, Naeije, Robert, Bossone, E., Ferrara, F., Gargani, Luna, Armstrong, W.F., Agoston, Gergely, Cittadini, Antonio, Citro, Rodolfo, D'Alto, M., D'Andrea, A., Dellegrottaglie, Santo, De Luca, Nicola, Di Salvo, Giovanni, Ghio, S., Grünig, Ekkehard, Guazzi, Marco, Kasprzak, Joanna J.M., Kolias, Theodore John, Kovacs, Gabor, Lancellotti, Patrizio, La Gerche, André, Limongelli, Giuseppe, Marra, A.M., Moreo, Antonella, Ostenfeld, Ellen, Pieri, Francesco, Pratali, Lorenza, Rudski, Lawrence Glenn, Saggar, R., Scalese, Marco, Selton-Suty, Christine, Serra, Walter, Stanziola, Anna Agnese, Voilliot, Damien, Vriz, Olga, Naeije, Robert, and Bossone, E.

Abstract

The Right Heart International Network is a multicenter international study aiming to prospectively collect exercise Doppler echocardiography tests of the right heart pulmonary circulation unit (RHPCU) in large cohorts of healthy subjects, elite athletes, and individuals at risk of or with overt pulmonary hypertension. It is going to provide standardization of exercise stress echocardiography of RHPCU and explore the full physiopathologic response., SCOPUS: re.j, info:eu-repo/semantics/published

Published
2018

29. A multicentric quality-control study of exercise Doppler echocardiography of the right heart and the pulmonary circulation. The RIGHT Heart International NETwork (RIGHT-NET).

Author

Ferrara, Francesco, Gargani, Luna, Contaldi, Carla, Agoston, Gergely, Argiento, Paola, Armstrong, William F., Bandera, Francesco, Cademartiri, Filippo, Citro, Rodolfo, Cittadini, Antonio, Cocchia, Rosangela, D'Alto, Michele, D'Andrea, Antonello, Douschan, Philipp, Ghio, Stefano, Grünig, Ekkehard, Guazzi, Marco, Guida, Stefania, Kasprzak, Jaroslaw D., and Kolias, Theodore John

Subjects
DOPPLER echocardiography, CORONARY circulation, PULMONARY circulation, VENTRICULAR ejection fraction, INTRACLASS correlation
Abstract

Purpose: This study was a quality-control study of resting and exercise Doppler echocardiography (EDE) variables measured by 19 echocardiography laboratories with proven experience participating in the RIGHT Heart International NETwork.Methods: All participating investigators reported the requested variables from ten randomly selected exercise stress tests. Intraclass correlation coefficients (ICC) were calculated to evaluate the inter-observer agreement with the core laboratory. Inter-observer variability of resting and peak exercise tricuspid regurgitation velocity (TRV), right ventricular outflow tract acceleration time (RVOT Act), tricuspid annular plane systolic excursion (TAPSE), tissue Doppler tricuspid lateral annular systolic velocity (S'), right ventricular fractional area change (RV FAC), left ventricular outflow tract velocity time integral (LVOT VTI), mitral inflow pulsed wave Doppler velocity (E), diastolic mitral annular velocity by TDI (e') and left ventricular ejection fraction (LVEF) were measured.Results: The accuracy of 19 investigators for all variables ranged from 99.7 to 100%. ICC was > 0.90 for all observers. Inter-observer variability for resting and exercise variables was for TRV = 3.8 to 2.4%, E = 5.7 to 8.3%, e' = 6 to 6.5%, RVOT Act = 9.7 to 12, LVOT VTI = 7.4 to 9.6%, S' = 2.9 to 2.9% and TAPSE = 5.3 to 8%. Moderate inter-observer variability was found for resting and peak exercise RV FAC (15 to 16%). LVEF revealed lower resting and peak exercise variability of 7.6 and 9%.Conclusions: When performed in expert centers EDE is a reproducible tool for the assessment of the right heart and the pulmonary circulation. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

30. Stress echo 2020 : the international stress echo study in ischemic and non-ischemic heart disease

Author

Picano, Eugenio, Ciampi, Quirino, Citro, Rodolfo, D'Andrea, Antonello, Scali, Maria Chiara, Cortigiani, Lauro, Olivotto, Iacopo, Mori, Fabio, Galderisi, Maurizio, Costantino, Marco Fabio, Pratali, Lorenza, Salvo, Giovanni di, Bossone, Eduardo, Ferrara, Francesco, Gargani, Luna, Rigo, Fausto, Gaibazzi, Nicola, Limongelli, Giuseppe, Pacileo, Giuseppe, Andreassi, Maria Grazia, Pinamonti, Bruno, Massa, Laura, Torres, Marco Antonio Rodrigues, Miglioranza, Marcelo H., Daros, Clarissa Borguezan, Pretto, José Luis de Castro e Silva, Beleslin, Branko, Djordjevic-Dikic, Ana, Varga, Albert, Palinkas, Attila, Agoston, Gergely, Gregori, Dario, Trambaiolo, Paolo, Severino, Sergio, Arystan, Ayana, Paterni, Marco, Carpeggiani, Clara, and Colonna, Paolo

Subjects
Ecocardiografia sob estresse, Stress echocardiography, Prognóstico, Efetividade, Diagnóstico por imagem, Effectiveness, Prognosis, Imaging
Abstract

Background: Stress echocardiography (SE) has an established role in evidence-based guidelines, but recently its breadth and variety of applications have extended well beyond coronary artery disease (CAD). We lack a prospective research study of SE applications, in and beyond CAD, also considering a variety of signs in addition to regional wall motion abnormalities. Methods: In a prospective, multicenter, international, observational study design, > 100 certified high-volume SE labs (initially from Italy, Brazil, Hungary, and Serbia) will be networked with an organized system of clinical, laboratory and imaging data collection at the time of physical or pharmacological SE, with structured follow-up information. The study is endorsed by the Italian Society of Cardiovascular Echography and organized in 10 subprojects focusing on: contractile reserve for prediction of cardiac resynchronization or medical therapy response; stress B-lines in heart failure; hypertrophic cardiomyopathy; heart failure with preserved ejection fraction; mitral regurgitation after either transcatheter or surgical aortic valve replacement; outdoor SE in extreme physiology; right ventricular contractile reserve in repaired Tetralogy of Fallot; suspected or initial pulmonary arterial hypertension; coronary flow velocity, left ventricular elastance reserve and B-lines in known or suspected CAD; identification of subclinical familial disease in genotype-positive, phenotype- negative healthy relatives of inherited disease (such as hypertrophic cardiomyopathy). Results: We expect to recruit about 10,000 patients over a 5-year period (2016-2020), with sample sizes ranging from 5,000 for coronary flow velocity/ left ventricular elastance/ B-lines in CAD to around 250 for hypertrophic cardiomyopathy or repaired Tetralogy of Fallot. This data-base will allow to investigate technical questions such as feasibility and reproducibility of various SE parameters and to assess their prognostic value in different clinical scenarios. Conclusions: The study will create the cultural, informatic and scientific infrastructure connecting high-volume, accredited SE labs, sharing common criteria of indication, execution, reporting and image storage of SE to obtain original safety, feasibility, and outcome data in evidence-poor diagnostic fields, also outside the established core application of SE in CAD based on regional wall motion abnormalities. The study will standardize procedures, validate emerging signs, and integrate the new information with established knowledge, helping to build a next-generation SE lab without inner walls.

Published
2017

31. B-lines with Lung Ultrasound: The Optimal Scan Technique at Rest and During Stress

Author

Scali, Maria Chiara, primary, Zagatina, Angela, additional, Simova, Iana, additional, Zhuravskaya, Nadezhda, additional, Ciampi, Quirino, additional, Paterni, Marco, additional, Marzilli, Mario, additional, Carpeggiani, Clara, additional, Picano, Eugenio, additional, Citro, Rodolfo, additional, D'Andrea, Antonello, additional, Scali, Maria Chiara, additional, Cortigiani, Lauro, additional, Olivotto, Iacopo, additional, Mori, Fabio, additional, Galderisi, Maurizio, additional, Costantino, Marco Fabio, additional, Pratali, Lorenza, additional, di Salvo, Giovanni, additional, Bossone, Eduardo, additional, Ferrara, Francesco, additional, Kasprszak, Jaroslaw D., additional, Rigo, Fausto, additional, Gaibazzi, Nicola, additional, Limongelli, Giuseppe, additional, Pacileo, Giuseppe, additional, Severino, Sergio, additional, Pinamonti, Bruno, additional, Massa, Laura, additional, Torres, Marco A.R., additional, Miglioranza, Marcelo H., additional, Daros, Clarissa Borguezan, additional, Luis de Castro e Silva Pretto, José, additional, Djordjevic-Dikic, Ana, additional, Dekleva, Milica, additional, Varga, Albert, additional, Agoston, Gergely, additional, Palinkas, Attila, additional, Amor, Miguel, additional, Lowenstein, Jorge, additional, Merlo, Pablo, additional, Celutkiene, Jelena, additional, Perez, Julio E., additional, Trambaiolo, Paolo, additional, Gregori, Dario, additional, Colonna, Paolo, additional, Andreassi, Maria Grazia, additional, De Nes, Michele, additional, and Arystan, Ayana, additional

Published
2017
Full Text
View/download PDF

32. Stress echo 2020: the international stress echo study in ischemic and non-ischemic heart disease

Author

Picano, Eugenio, primary, Ciampi, Quirino, additional, Citro, Rodolfo, additional, D’Andrea, Antonello, additional, Scali, Maria Chiara, additional, Cortigiani, Lauro, additional, Olivotto, Iacopo, additional, Mori, Fabio, additional, Galderisi, Maurizio, additional, Costantino, Marco Fabio, additional, Pratali, Lorenza, additional, Di Salvo, Giovanni, additional, Bossone, Eduardo, additional, Ferrara, Francesco, additional, Gargani, Luna, additional, Rigo, Fausto, additional, Gaibazzi, Nicola, additional, Limongelli, Giuseppe, additional, Pacileo, Giuseppe, additional, Andreassi, Maria Grazia, additional, Pinamonti, Bruno, additional, Massa, Laura, additional, Torres, Marco A. R., additional, Miglioranza, Marcelo H., additional, Daros, Clarissa Borguezan, additional, de Castro e Silva Pretto, José Luis, additional, Beleslin, Branko, additional, Djordjevic-Dikic, Ana, additional, Varga, Albert, additional, Palinkas, Attila, additional, Agoston, Gergely, additional, Gregori, Dario, additional, Trambaiolo, Paolo, additional, Severino, Sergio, additional, Arystan, Ayana, additional, Paterni, Marco, additional, Carpeggiani, Clara, additional, and Colonna, Paolo, additional

Published
2017
Full Text
View/download PDF

33. Heart Failure 2019.

Author

Gatzov, Plamen, Monsuez, Jean-Jacques, Agoston, Gergely, Aschermann, Michael, Badran, Hala Mahfouz, Cohen, Ariel, Huber, Kurt, Shlyakhto, Evgeny, Ural, Dilek, Ferreira-Gonzalez, Ignacio, and Alfonso, Fernando

Subjects
HEART failure, DRUG therapy, CARDIOVASCULAR diseases, THERAPEUTICS, SKELETAL muscle
Abstract

The article presents the discussion on studies on heart failure (HF) management published in 2019 by high-ranking impact factor international journals focusing on drug therapy. Topics include inequalities in the prevalence of risk factors, cardiovascular disease burden, cardiovascular mortality, and implementation of some therapeutic methods; and reporting the potential for differentiation, regeneration, and growth of satellite skeletal muscle precursor cells.

Published
2021
Full Text
View/download PDF

34. Left atrial dysfunction detected by speckle tracking in patients with systemic sclerosis

Author

Agoston, G, Gargani, L, Miglioranza Marcelo, H, Caputo, M, Badano, L, Moreo, A, Muraru, D, Mondillo, S, Moggi Pignone, A, Matucci Cerinic, M, Sicari, R, Picano, E, Varga, A, Agoston Gergely, Gargani Luna, Miglioranza Marcelo Haertel, Caputo Maria, Badano Luigi, Moreo Antonella, Muraru Denisa, Mondillo Sergio, Moggi Pignone Alberto, Matucci Cerinic Marco, Sicari Rosa, Picano Eugenio, Varga Albert, Agoston, G, Gargani, L, Miglioranza Marcelo, H, Caputo, M, Badano, L, Moreo, A, Muraru, D, Mondillo, S, Moggi Pignone, A, Matucci Cerinic, M, Sicari, R, Picano, E, Varga, A, Agoston Gergely, Gargani Luna, Miglioranza Marcelo Haertel, Caputo Maria, Badano Luigi, Moreo Antonella, Muraru Denisa, Mondillo Sergio, Moggi Pignone Alberto, Matucci Cerinic Marco, Sicari Rosa, Picano Eugenio, and Varga Albert

Abstract

Aim. To assess whether STE strain parameters may detect early alterations in LA function in SSc patients. Methods. Forty-two SSc patients (Group 1, age 50 ± 14 years, 95% females) without clinical evidence for cardiac involvement and 42 age- and gender-matched control subjects (Group 2, age 49 ± 13 years, 95% females) were evaluated with comprehensive 2D and Doppler echocardiography, including tissue Doppler imaging analysis. Positive peak left atrial longitudinal strain ( pos peak), second positive left atrial longitudinal strain (sec pos peak), and negative left atrial longitudinal strain ( neg peak) were measured using a 12-segment model for the LA, by commercially available semi-automated 2D speckle-tracking software (EchoPac PC version 108.1.4, GE Healthcare, Horten, Norway). Results: All SSc patients had a normal left ventricular ejection fraction (63.1 ± 4%). SSc patients did not differ from controls in E/A (Group 1 = 1.1 ± 0.4 vs Group 2 = 1.3 ± 0.4, p =.14) or pulmonary arterial systolic pressure (Group 1 = 24.1 ± 8 mmHg vs Group 2 = 21 ± 7 mmHg, p =.17). SSc patients did not show significantly different indexed LA volumes (Group 1 = 24.9 ± 5.3 ml/m2 vs Group 2 = 24.7 ± 4.4 ml/m2, p =.8), whereas E/e' ratio was significantly higher in SSc (Group 1 = 7.6 ± 2.4 vs Group 2 = 6.5 ± 1.7, p<0.05), although still within normal values. LA strain values were significantly different between the two groups ( pos peak Group 1 = 31.3 ± 4.2% vs Group 2 = 35.0 ± 7.6%, p <.01, sec pos peak Group 1 = 18.4 ± 4 vs Group 2 = 21.4 ± 7.6, p < 0.05). Conclusion: 2D speckle-tracking echocardiography is a sensitive tool to assess impairment of LA mechanics, which is detectable in absence of changes in LA size and volume, and may represent an early sign of cardiac involvement in patients with SSc. Background: Cardiac involvement is a relevant clinical finding in systemic sclerosis (SSc) and is associated with poor prognosis. Left atrial (LA) remodeling and/or dysfunction ca

Published
2014

35. Left atrial dysfunction detected by speckle tracking in patients with systemic sclerosis

Author

Agoston, Gergely, primary, Gargani, Luna, additional, Miglioranza, Marcelo Haertel, additional, Caputo, Maria, additional, Badano, Luigi Paolo, additional, Moreo, Antonella, additional, Muraru, Denisa, additional, Mondillo, Sergio, additional, Moggi Pignone, Alberto, additional, Matucci Cerinic, Marco, additional, Sicari, Rosa, additional, Picano, Eugenio, additional, and Varga, Albert, additional

Published
2014
Full Text
View/download PDF

36. B-lines with Lung Ultrasound: The Optimal Scan Technique at Rest and During Stress

Author

Maria Chiara Scali, Angela Zagatina, Iana Simova, Nadezhda Zhuravskaya, Quirino Ciampi, Marco Paterni, Mario Marzilli, Clara Carpeggiani, Eugenio Picano, Rodolfo Citro, Antonello D'Andrea, Lauro Cortigiani, Iacopo Olivotto, Fabio Mori, Maurizio Galderisi, Marco Fabio Costantino, Lorenza Pratali, Giovanni di Salvo, Eduardo Bossone, Francesco Ferrara, Jaroslaw D. Kasprszak, Fausto Rigo, Nicola Gaibazzi, Giuseppe Limongelli, Giuseppe Pacileo, Sergio Severino, Bruno Pinamonti, Laura Massa, Marco A.R. Torres, Marcelo H. Miglioranza, Clarissa Borguezan Daros, José Luis de Castro e Silva Pretto, Ana Djordjevic-Dikic, Milica Dekleva, Albert Varga, Gergely Agoston, Attila Palinkas, Miguel Amor, Jorge Lowenstein, Pablo Merlo, Jelena Celutkiene, Julio E. Perez, Paolo Trambaiolo, Dario Gregori, Paolo Colonna, Maria Grazia Andreassi, Michele De Nes, Ayana Arystan, Scali, Maria Chiara, Zagatina, Angela, Simova, Iana, Zhuravskaya, Nadezhda, Ciampi, Quirino, Paterni, Marco, Marzilli, Mario, Carpeggiani, Clara, Picano, Eugenio, Citro, Rodolfo, D'Andrea, Antonello, Cortigiani, Lauro, Olivotto, Iacopo, Mori, Fabio, Galderisi, Maurizio, Costantino, Marco Fabio, Pratali, Lorenza, di Salvo, Giovanni, Bossone, Eduardo, Ferrara, Francesco, Kasprszak, Jaroslaw D., Rigo, Fausto, Gaibazzi, Nicola, Limongelli, Giuseppe, Pacileo, Giuseppe, Severino, Sergio, Pinamonti, Bruno, Massa, Laura, Torres, Marco A. R., Miglioranza, Marcelo H., Daros, Clarissa Borguezan, Luis de Castro e Silva Pretto, José, Djordjevic-Dikic, Ana, Dekleva, Milica, Varga, Albert, Agoston, Gergely, Palinkas, Attila, Amor, Miguel, Lowenstein, Jorge, Merlo, Pablo, Celutkiene, Jelena, Perez, Julio E., Trambaiolo, Paolo, Gregori, Dario, Colonna, Paolo, Andreassi, Maria Grazia, De Nes, Michele, and Arystan, Ayana

Subjects
Male, medicine.medical_specialty, Acoustics and Ultrasonics, Stre, Rest, Physiological, Biophysics, 030204 cardiovascular system & hematology, Stress, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, Stress, Physiological, medicine, Humans, Radiology, Nuclear Medicine and imaging, Prospective Studies, 030212 general & internal medicine, Exercise, Lung, Rest (music), Ultrasonography, Water, Extravascular Lung Water, Female, Middle Aged, Exercise Test, Radiological and Ultrasound Technology, business.industry, Ultrasound, Exercise stress, medicine.disease, Lung ultrasound, Surgery, medicine.anatomical_structure, Lung water, Biophysic, Parasternal line, business, Nuclear medicine
Abstract

Various lung ultrasound (LUS) scanning modalities have been proposed for the detection of B-lines, also referred to as ultrasound lung comets , which are an important indication of extravascular lung water at rest and after exercise stress echo (ESE). The aim of our study was to assess the lung water spatial distribution ( comet map ) at rest and after ESE. We performed LUS at rest and immediately after semi-supine ESE in 135 patients (45 women, 90 men; age 62 ± 12 y, resting left ventricular ejection fraction = 41 ± 13%) with known or suspected heart failure or coronary artery disease. B-lines were measured by scanning 28 intercostal spaces (ISs) on the antero-lateral chest, 2nd–5th IS, along with the midaxillary (MA), anterior axillary (AA), mid-clavicular (MC) and parasternal (PS) lines. Complete 28-region, 16-region (3rd and 4th IS), 8-region (3rd IS), 4-region (3rd IS, only AA and MA) and 1-region (left 3rd IS, MA) scans were analyzed. In each space, the B-lines were counted from 0 = black lung to 10 = white lung. Interpretable images were obtained in all spaces (feasibility = 100 %). B-lines (>0 in at least 1 space) were present at ESE in 93 patients (69%) and absent in 42. More B-lines were found in the 3rd IS and along AA and MA lines. The B-line cumulative distribution was symmetric at rest (right/left = 1.10) and asymmetric with left lung predominance during stress (right/left = 0.67). The correlation of per-patient B-line number between 28-S and 16-S (R 2 = 0.9478), 8-S (R 2 = 0.9478) and 4-S scan (R 2 = 0.9146) was excellent, but only good with 1-S (R 2 = 0.8101). The average imaging and online analysis time were 5 s per space. In conclusion, during ESE, the comet map of lung water accumulation follows a predictable spatial pattern with wet spots preferentially aligned with the third IS and along the AA and MA lines. The time-saving 4-region scan is especially convenient during stress, simply dismissing dry regions and focusing on wet regions alone.

Published
2017

37. Feasibility and value of two-dimensional volumetric stress echocardiography.

Author

Bombardini T, Zagatina A, Ciampi Q, Cortigiani L, D'Andrea A, Borguezan Daros C, Zhuravskaya N, Kasprzak JD, Wierzbowska-Drabik K, de Castro E Silva Pretto JL, Djordjevic-Dikic A, Beleslin B, Petrovic M, Boskovic N, Tesic M, Monte IP, Simova I, Vladova M, Boshchenko A, Ryabova T, Citro R, Amor M, Vargas Mieles PE, Arbucci R, Dodi C, Rigo F, Gligorova S, Dekleva M, Severino S, Torres MA, Salustri A, Rodrìguez-Zanella H, Costantino FM, Varga A, Agoston G, Bossone E, Ferrara F, Gaibazzi N, Rabia G, Celutkiene J, Haberka M, Mori F, D'Alfonso MG, Reisenhofer B, Camarozano AC, Salamé M, Szymczyk E, Wejner-Mik P, Wdowiak-Okrojek K, Kovacevic Preradovic T, Lattanzi F, Morrone D, Scali MC, Ostojic M, Nikolic A, Re F, Barbieri A, DI Salvo G, Colonna P, DE Nes M, Paterni M, Merlo PM, Lowenstein J, Carpeggiani C, Gregori D, and Picano E

Subjects
Aged, Dobutamine, Echocardiography methods, Feasibility Studies, Humans, Male, Middle Aged, Echocardiography, Stress methods, Heart Failure
Abstract

Background: Stroke volume response during stress is a major determinant of functional status in heart failure and can be measured by two-dimensional (2-D) volumetric stress echocardiography (SE). The present study hypothesis is that SE may identify mechanisms underlying the change in stroke volume by measuring preload reserve through end-diastolic volume (EDV) and left ventricular contractile reserve (LVCR) with systolic blood pressure and end-systolic volume (ESV)., Methods: We enrolled 4735 patients (age 63.6±11.3 years, 2800 male) referred to SE for known or suspected coronary artery disease (CAD) and/or heart failure (HF) in 21 SE laboratories in 8 countries. In addition to regional wall motion abnormalities (RWMA), force was measured at rest and peak stress as the ratio of systolic blood pressure by cuff sphygmomanometer/ESV by 2D with Simpson's or linear method. Abnormal values of LVCR (peak/rest) based on force were ≤1.10 for dipyridamole (N.=1992 patients) and adenosine (N.=18); ≤2.0 for exercise (N.=2087) or dobutamine (N.=638)., Results: Force-based LVCR was obtained in all 4735 patients. Lack of stroke volume increase during stress was due to either abnormal LVCR and/or blunted preload reserve, and 57% of patients with abnormal LVCR nevertheless showed increase in stroke volume., Conclusions: Volumetric SE is highly feasible with all stresses, and more frequently impaired in presence of ischemic RWMA, absence of viability and reduced coronary flow velocity reserve. It identifies an altered stroke volume response due to reduced preload and/or contractile reserve.

Published
2022
Full Text
View/download PDF

38. Stress Echo 2030: The Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging.

Author

Picano E, Ciampi Q, Cortigiani L, Arruda-Olson AM, Borguezan-Daros C, de Castro E Silva Pretto JL, Cocchia R, Bossone E, Merli E, Kane GC, Varga A, Agoston G, Scali MC, Morrone D, Simova I, Samardjieva M, Boshchenko A, Ryabova T, Vrublevsky A, Palinkas A, Palinkas ED, Sepp R, Torres MAR, Villarraga HR, Preradović TK, Citro R, Amor M, Mosto H, Salamè M, Leeson P, Mangia C, Gaibazzi N, Tuttolomondo D, Prota C, Peteiro J, Van De Heyning CM, D'Andrea A, Rigo F, Nikolic A, Ostojic M, Lowenstein J, Arbucci R, Haber DML, Merlo PM, Wierzbowska-Drabik K, Kasprzak JD, Haberka M, Camarozano AC, Ratanasit N, Mori F, D'Alfonso MG, Tassetti L, Milazzo A, Olivotto I, Marchi A, Rodriguez-Zanella H, Zagatina A, Padang R, Dekleva M, Djordievic-Dikic A, Boskovic N, Tesic M, Giga V, Beleslin B, Di Salvo G, Lorenzoni V, Cameli M, Mandoli GE, Bombardini T, Caso P, Celutkiene J, Barbieri A, Benfari G, Bartolacelli Y, Malagoli A, Bursi F, Mantovani F, Villari B, Russo A, De Nes M, Carpeggiani C, Monte I, Re F, Cotrim C, Bilardo G, Saad AK, Karuzas A, Matuliauskas D, Colonna P, Antonini-Canterin F, Pepi M, Pellikka PA, and The Stress Echo Study Group Of The Italian Society Of Echocardiography And Cardiovascular Imaging Siecvi

Abstract

With stress echo (SE) 2020 study, a new standard of practice in stress imaging was developed and disseminated: the ABCDE protocol for functional testing within and beyond CAD. ABCDE protocol was the fruit of SE 2020, and is the seed of SE 2030, which is articulated in 12 projects: 1-SE in coronary artery disease (SECAD); 2-SE in diastolic heart failure (SEDIA); 3-SE in hypertrophic cardiomyopathy (SEHCA); 4-SE post-chest radiotherapy and chemotherapy (SERA); 5-Artificial intelligence SE evaluation (AI-SEE); 6-Environmental stress echocardiography and air pollution (ESTER); 7-SE in repaired Tetralogy of Fallot (SETOF); 8-SE in post-COVID-19 (SECOV); 9: Recovery by stress echo of conventionally unfit donor good hearts (RESURGE); 10-SE for mitral ischemic regurgitation (SEMIR); 11-SE in valvular heart disease (SEVA); 12-SE for coronary vasospasm (SESPASM). The study aims to recruit in the next 5 years (2021-2025) ≥10,000 patients followed for ≥5 years (up to 2030) from ≥20 quality-controlled laboratories from ≥10 countries. In this COVID-19 era of sustainable health care delivery, SE2030 will provide the evidence to finally recommend SE as the optimal and versatile imaging modality for functional testing anywhere, any time, and in any patient.

Published
2021
Full Text
View/download PDF

39. Heart Failure 2019 Insights from the National Society of Cardiology journals.

Author

Gatzov P, Monsuez JJ, Agoston G, Aschermann M, Badran HM, Cohen A, Huber K, Shlyakhto E, Ural D, Ferreira-Gonzalez I, and Alfonso F

Subjects
Europe epidemiology, Heart Valve Diseases complications, Heart Valve Diseases therapy, Humans, Journal Impact Factor, Societies, Transcatheter Aortic Valve Replacement, Cardiology, Heart Failure diagnosis, Heart Failure epidemiology, Heart Failure etiology, Heart Failure therapy, Information Dissemination methods, Periodicals as Topic
Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results