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395 results on '"Aggrephagy"'

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1. The Mechanistic Link Between Tau-Driven Proteotoxic Stress and Cellular Senescence in Alzheimer's Disease.

2. The essential role of CCT2 in the regulation of aggrephagy.

3. Phosphorylation of the selective autophagy receptor TAX1BP1 by TBK1 and IKBKE/IKKi promotes ATG8-family protein-dependent clearance of MAVS aggregates.

4. Single‐cell sequencing reveals the correlation of aggrephagy signaling and multiple myeloma immune microenvironment composition.

5. Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis

6. Single-cell aggrephagy-related patterns facilitate tumor microenvironment intercellular communication, influencing osteosarcoma progression and prognosis.

7. Characterization of aggrephagy-related genes to predict the progression of liver fibrosis from multi-omics profiles

8. Aggrephagy-related gene signature correlates with survival and tumor-associated macrophages in glioma: Insights from single-cell and bulk RNA sequencing

9. Inhibition of SQSTM1 S403 phosphorylation facilitates the aggresome formation of ubiquitinated proteins during proteasome dysfunction

10. The evolution of selective autophagy as a mechanism of oxidative stress response: The evolutionarily acquired ability of selective autophagy receptors to respond to oxidative stress is beneficial for human longevity.

11. Inhibition of SQSTM1 S403 phosphorylation facilitates the aggresome formation of ubiquitinated proteins during proteasome dysfunction.

12. Aggrephagy-related patterns in tumor microenvironment, prognosis, and immunotherapy for acute myeloid leukemia: a comprehensive single-cell RNA sequencing analysis.

13. Aggrephagy-related LncRNAs index: A predictor for HCC prognosis, immunotherapy efficacy, and chemosensitivity.

15. Targeting the autophagy-lysosomal pathway in Huntington disease: a pharmacological perspective.

16. Targeting of biomolecular condensates to the autophagy pathway.

17. Protein Aggregates and Aggrephagy in Myopathies.

18. How RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates

19. An Aggrephagy-Related LncRNA Signature for the Prognosis of Pancreatic Adenocarcinoma.

20. Multifaceted roles of TAX1BP1 in autophagy.

21. The Genetics of Autophagy in Multicellular Organisms.

22. The essential role of CCT2 in the regulation of aggrephagy.

23. HYPK coordinates degradation of polyneddylated proteins by autophagy.

24. Physiological functions of ULK1/2.

25. Autophagy Modulation in Aggresome Formation: Emerging Implications and Treatments of Alzheimer's Disease.

26. Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer's Disease.

27. The tail domain of PRRSV NSP2 plays a key role in aggrephagy by interacting with 14-3-3ε

28. ATPase-regulated autophagosome biogenesis.

29. A switch of chaperonin function regulates the clearance of solid protein aggregates.

30. TRIM28 functions as a negative regulator of aggresome formation.

31. Selective autophagy: the rise of the zebrafish model.

32. A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.

33. Autophagy preferentially degrades non-fibrillar polyQ aggregates.

34. CCT2, a newly identified aggrephagy receptor in mammals, specifically mediates the autophagic clearance of solid protein aggregates.

35. Evolutionarily acquired response of selective autophagy receptors provides resilience against oxidative stress.

36. Autophagy Modulation in Aggresome Formation: Emerging Implications and Treatments of Alzheimer’s Disease

37. XCT 790 is a pharmacological aggrephagy inducer in a yeast model of proteotoxicity.

38. Complement Membrane Attack Complexes Disrupt Proteostasis to Function as Intracellular Alarmins.

40. Pharmacological Tools to Modulate Autophagy in Neurodegenerative Diseases.

41. The tissue- and developmental stage-specific involvement of autophagy genes in aggrephagy.

42. Characterization of aggrephagy in exercise-induced muscle damage.

43. Selective autophagy of cytosolic protein aggregates involves ribosome-free rough endoplasmic reticulum.

44. Phase Separation in Regulation of Aggrephagy.

45. Accumulation and Cellular Clearance of IAPP and Proteotoxicity of ATTR in Drosophila Models

46. Aberrant Stress Granule Dynamics and Aggrephagy in ALS Pathogenesis

47. Selective Autophagy as a Potential Therapeutic Target in Age-Associated Pathologies

48. Quercetin in Tartary Buckwheat Induces Autophagy against Protein Aggregations

49. TRIM16 employs NRF2, ubiquitin system and aggrephagy for safe disposal of stress-induced misfolded proteins

50. Aggrephagy-related gene signature correlates with survival and tumor-associated macrophages in glioma: Insights from single-cell and bulk RNA sequencing.

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