634 results on '"Aggarwal, Aneel"'
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2. Cryo-EM structure of the Rev1–Polζ holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis
3. Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation
4. Nucleic acid mediated activation of a short prokaryotic Argonaute immune system
5. Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides
6. Signal-induced enhancer activation requires Ku70 to read topoisomerase1–DNA covalent complexes
7. H19 influenza A virus exhibits species-specific MHC class II receptor usage
8. High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development
9. Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly
10. Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
11. Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program
12. Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch
13. FANCI functions as a repair/apoptosis switch in response to DNA crosslinks
14. Shape of promoter antisense RNAs regulates ligand-induced transcription activation
15. A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding Agent
16. Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis
17. Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease
18. Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase
19. Ligand-Dependent Enhancer Activation Regulated by Topoisomerase-I Activity
20. Burkholderia cenocepaciaepigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation
21. Eukaryotic DNA polymerases
22. Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis
23. Brd4 and JMJD6-Associated Anti-Pause Enhancers in Regulation of Transcriptional Pause Release
24. Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme
25. Proximity-Induced Activation of Human Cdc34 through Heterologous Dimerization
26. Rev1 Employs a Novel Mechanism of DNA Synthesis Using a Protein Template
27. Structure of Adeno-Associated Virus Type 2 Rep40-ADP Complex: Insight into Nucleotide Recognition and Catalysis by Superfamily 3 Helicases
28. Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer
29. Nucleic Acid Mediated Activation of a Short Prokaryotic Argonaute Immune System
30. Allosteric Effects of Pit-1 DNA Sites on Long-Term Repression in Cell Type Specification
31. Protein–nucleic acid interactions: unlocking mysteries old and new
32. Protein–nucleic acid interactions
33. FokI Dimerization is Required for DNA Cleavage
34. Structure of FokI has Implications for DNA Cleavage
35. Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals
36. Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensatesin vitro
37. A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling
38. Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2)
39. Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase η
40. Supplementary Data from SOX11 Inhibitors Are Cytotoxic in Mantle Cell Lymphoma
41. An Inhibitor of PIDDosome Formation
42. Phosphatidylinositol 4,5-Bisphosphate Clusters the Cell Adhesion Molecule CD44 and Assembles a Specific CD44-Ezrin Heterocomplex, as Revealed by Small Angle Neutron Scattering
43. Bisphosphonates inactivate human EGFRs to exert antitumor actions
44. Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer
45. Structural basis for polymerase η–promoted resistance to the anticancer nucleoside analog cytarabine
46. The focal facial dermal dysplasias: phenotypic spectrum and molecular genetic heterogeneity
47. Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation
48. Human DNA Polymerase η Is Pre-Aligned for dNTP Binding and Catalysis
49. Role of Human DNA Polymerase κ in Extension Opposite from a cis–syn Thymine Dimer
50. DNA Synthesis across an Abasic Lesion by Yeast Rev1 DNA Polymerase
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