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466 results on '"Agati, Luciano"'

2. Methotrexate & rheumatoid arthritis associated atherosclerosis: A narrative review of multidisciplinary approach for risk modification by the international board of experts

Author

Avagimyan, Ashot, Fogacci, Federica, Pogosova, Nana, Kakturskiy, Lev, Jndoyan, Zinaida, Faggiano, Andrea, Bairamyan, Tamara, Agati, Luciano, Sattar, Yasar, Mkrchyan, Lusine, Avetisyan, Gayane, Ginosyan, Knarik, Aznauryan, Anahit, Sahakyan, Karmen, Trofimenko, Artem, Urazova, Olga, Mikhaleva, Liudmila, Vandysheva, Rositsa, Kogan, Eugenia, Demura, Tatiana, KC, Manish, Shafie, Davood, Nicola, Stefania, Brussino, Luisa, Cicero, Arrigo, Biondi-Zoccai, Giuseppe, and Sarrafzadegan, Nizal

Published
2024
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3. Diabetic Cardiomyopathy: 2023 Update by the International Multidisciplinary Board of Experts

Author

Avagimyan, Ashot, Fogacci, Federica, Pogosova, Nana, Kakrurskiy, Lev, Kogan, Eugenia, Urazova, Olga, Kobalava, Zhanna, Mikhaleva, Liudmila, Vandysheva, Rositsa, Zarina, Gioeva, Trofimenko, Artem, Navasardyan, Grizelda, Mkrtchyan, Lusine, Galli, Mattia, Jndoyan, Zinaida, Aznauryan, Anait, Saahakyan, Karmen, Agati, Luciano, Shafie, Davood, Cicero, Arrigo, Salvo, Giovanni Di, and Sarrafzadegan, Nizal

Published
2024
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4. HIV-Related Atherosclerosis: State-of-the-Art-Review

Author

Avagimyan, Ashot, Pogosova, Nana, Kakturskiy, Lev, Sheibani, Mohammad, Urazova, Olga, Trofimenko, Artem, Navarsdyan, Grizelda, Jndoyan, Zinaida, Abgaryan, Kristina, Fogacci, Federica, Galli, Mattia, Agati, Luciano, Kobalava, Zhanna, Shafie, Davood, Marzilli, Mario, Gogiashvili, Liana, and Sarrafzadegan, Nizal

Published
2023
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7. Myocardial contractility recovery following acute pressure unloading after transcatheter aortic valve intervention (TAVI) in patients with severe aortic stenosis and different left ventricular geometry: a multilayer longitudinal strain echocardiographicanalysis

Author

Cimino, Sara, Monosilio, Sara, Luongo, Federico, Neccia, Matteo, Birtolo, Lucia Ilaria, Salvi, Nicolò, Filomena, Domenico, Mancone, Massimo, Fedele, Francesco, Agati, Luciano, and Maestrini, Viviana

Published
2021
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10. Methotrexate & Rheumatoid Arthritis Associated Atherosclerosis: A Narrative Review of Multidisciplinary Approach for Risk Modification by the International Board of Experts

Author

Avagimyan, Ashot, primary, Fogaci, Federica, additional, Pogosova, Nana, additional, Kakturskiy, Lev, additional, Jndoyan, Zinaida, additional, Faggiano, Andrea, additional, Bairamyan, Tamara, additional, Agati, Luciano, additional, Sattar, Yasar, additional, Mkrchyan, Lusine, additional, Ginosyan, Knarik, additional, Aznauryan, Anahit, additional, Sahakyan, Karmen, additional, Trofimenko, Artem, additional, Urazova, Olga, additional, Mikhaleva, Liudmila, additional, Vandysheva, Rositsa, additional, Kogan, Eugenia, additional, Demura, Tatiana, additional, KC, Manish, additional, Shafie, Davood, additional, Nicola, Stefania, additional, Brussino, Luisa, additional, Cicero, Arrigo, additional, Biondi-Zoccai, Giuseppe, additional, and Sarrafzadegan, Nizal, additional

Published
2023
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15. An exploratory cross-sectional study of subclinical vascular damage in patients with polymyalgia rheumatica

Author

Scrivo, Rossana, Silvestri, Valeria, Ciciarello, Francesco, Sessa, Paola, Rutigliano, Iolanda, Sestili, Cristina, La Torre, Giuseppe, Barbati, Cristiana, Altobelli, Alessio, Alessandri, Cristiano, Ceccarelli, Fulvia, Di Franco, Manuela, Priori, Roberta, Riccieri, Valeria, Sili Scavalli, Antonio, Spinelli, Francesca Romana, Agati, Luciano, Fedele, Francesco, Gossetti, Bruno, Conti, Fabrizio, and Valesini, Guido

Published
2020
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18. Myocardial Fibrosis at Cardiac MRI Helps Predict Adverse Clinical Outcome in Patients with Mitral Valve Prolapse

Author

Figliozzi, S, Georgiopoulos, G, Lopes, P, Bauer, K, Moura-Ferreira, S, Tondi, L, Mushtaq, S, Censi, S, Pavon, A, Bassi, I, Servato, M, Teske, A, Biondi, F, Filomena, D, Pica, S, Torlasco, C, Muraru, D, Monney, P, Quattrocchi, G, Maestrini, V, Agati, L, Monti, L, Pedrotti, P, Vandenberk, B, Squeri, A, Lombardi, M, Ferreira, A, Schwitter, J, Aquaro, G, Chiribiri, A, Rodríguez Palomares, J, Yilmaz, A, Andreini, D, Florian, A, Leiner, T, Abecasis, J, Badano, L, Bogaert, J, Masci, P, Figliozzi, Stefano, Georgiopoulos, Georgios, Lopes, Pedro M, Bauer, Klemens B, Moura-Ferreira, Sara, Tondi, Lara, Mushtaq, Saima, Censi, Stefano, Pavon, Anna Giulia, Bassi, Ilaria, Servato, Maria Luz, Teske, Arco J, Biondi, Federico, Filomena, Domenico, Pica, Silvia, Torlasco, Camilla, Muraru, Denisa, Monney, Pierre, Quattrocchi, Giuseppina, Maestrini, Viviana, Agati, Luciano, Monti, Lorenzo, Pedrotti, Patrizia, Vandenberk, Bert, Squeri, Angelo, Lombardi, Massimo, Ferreira, António M, Schwitter, Juerg, Aquaro, Giovanni Donato, Chiribiri, Amedeo, Rodríguez Palomares, José F, Yilmaz, Ali, Andreini, Daniele, Florian, Anca, Leiner, Tim, Abecasis, João, Badano, Luigi, Bogaert, Jan, Masci, Pier-Giorgio, Figliozzi, S, Georgiopoulos, G, Lopes, P, Bauer, K, Moura-Ferreira, S, Tondi, L, Mushtaq, S, Censi, S, Pavon, A, Bassi, I, Servato, M, Teske, A, Biondi, F, Filomena, D, Pica, S, Torlasco, C, Muraru, D, Monney, P, Quattrocchi, G, Maestrini, V, Agati, L, Monti, L, Pedrotti, P, Vandenberk, B, Squeri, A, Lombardi, M, Ferreira, A, Schwitter, J, Aquaro, G, Chiribiri, A, Rodríguez Palomares, J, Yilmaz, A, Andreini, D, Florian, A, Leiner, T, Abecasis, J, Badano, L, Bogaert, J, Masci, P, Figliozzi, Stefano, Georgiopoulos, Georgios, Lopes, Pedro M, Bauer, Klemens B, Moura-Ferreira, Sara, Tondi, Lara, Mushtaq, Saima, Censi, Stefano, Pavon, Anna Giulia, Bassi, Ilaria, Servato, Maria Luz, Teske, Arco J, Biondi, Federico, Filomena, Domenico, Pica, Silvia, Torlasco, Camilla, Muraru, Denisa, Monney, Pierre, Quattrocchi, Giuseppina, Maestrini, Viviana, Agati, Luciano, Monti, Lorenzo, Pedrotti, Patrizia, Vandenberk, Bert, Squeri, Angelo, Lombardi, Massimo, Ferreira, António M, Schwitter, Juerg, Aquaro, Giovanni Donato, Chiribiri, Amedeo, Rodríguez Palomares, José F, Yilmaz, Ali, Andreini, Daniele, Florian, Anca, Leiner, Tim, Abecasis, João, Badano, Luigi, Bogaert, Jan, and Masci, Pier-Giorgio

Abstract

Background: Patients with mitral valve prolapse (MVP) may develop adverse outcomes even in the absence of mitral regurgitation or left ventricular (LV) dysfunction. Purpose: To investigate the prognostic value of mitral annulus disjunction (MAD) and myocardial fibrosis at late gadolinium enhancement (LGE) cardiac MRI in patients with MVP without moderate-to-severe mitral regurgitation or LV dysfunction. Materials and Methods: In this longitudinal retrospective study, 118 144 cardiac MRI studies were evaluated between October 2007 and June 2020 at 15 European tertiary medical centers. Follow-up was from the date of cardiac MRI examination to June 2020; the minimum and maximum follow-up intervals were 6 months and 156 months, respectively. Patients were excluded if at least one of the following conditions was present: cardiomyopathy, LV ejection fraction less than 40%, ischemic heart disease, congenital heart disease, inflammatory heart disease, moderate or worse mitral regurgitation, participation in competitive sport, or electrocardiogram suggestive of channelopathies. In the remainder, cardiac MRI studies were reanalyzed, and patients were included if they were aged 18 years or older, MVP was diagnosed at cardiac MRI, and clinical information and electrocardiogram monitoring were available within 3 months from cardiac MRI examination. The end point was a composite of adverse outcomes: sustained ventricular tachycardia (VT), sudden cardiac death (SCD), or unexplained syncope. Multivariable Cox regression analysis was performed. Results: A total of 474 patients (mean age, 47 years ± 16 [SD]; 244 women) were included. Over a median follow-up of 3.3 years, 18 patients (4%) reached the study end point. LGE presence (hazard ratio, 4.2 [95% CI: 1.5, 11.9]; P = .006) and extent (hazard ratio, 1.2 per 1% increase [95% CI: 1.1, 1.4]; P = .006), but not MAD presence (P = .89), were associated with clinical outcome. LGE presence had incremental prognostic value over MVP severi

Published
2023

19. Myocardial Fibrosis at Cardiac MRI Helps Predict Adverse Clinical Outcome in Patients with Mitral Valve Prolapse

Author

Team Medisch, Circulatory Health, MS Radiologie, Figliozzi, Stefano, Georgiopoulos, Georgios, Lopes, Pedro M, Bauer, Klemens B, Moura-Ferreira, Sara, Tondi, Lara, Mushtaq, Saima, Censi, Stefano, Pavon, Anna Giulia, Bassi, Ilaria, Servato, Maria Luz, Teske, Arco J, Biondi, Federico, Filomena, Domenico, Pica, Silvia, Torlasco, Camilla, Muraru, Denisa, Monney, Pierre, Quattrocchi, Giuseppina, Maestrini, Viviana, Agati, Luciano, Monti, Lorenzo, Pedrotti, Patrizia, Vandenberk, Bert, Squeri, Angelo, Lombardi, Massimo, Ferreira, António M, Schwitter, Juerg, Aquaro, Giovanni Donato, Chiribiri, Amedeo, Rodríguez Palomares, José F, Yilmaz, Ali, Andreini, Daniele, Florian, Anca, Leiner, Tim, Abecasis, João, Badano, Luigi Paolo, Bogaert, Jan, Masci, Pier-Giorgio, Team Medisch, Circulatory Health, MS Radiologie, Figliozzi, Stefano, Georgiopoulos, Georgios, Lopes, Pedro M, Bauer, Klemens B, Moura-Ferreira, Sara, Tondi, Lara, Mushtaq, Saima, Censi, Stefano, Pavon, Anna Giulia, Bassi, Ilaria, Servato, Maria Luz, Teske, Arco J, Biondi, Federico, Filomena, Domenico, Pica, Silvia, Torlasco, Camilla, Muraru, Denisa, Monney, Pierre, Quattrocchi, Giuseppina, Maestrini, Viviana, Agati, Luciano, Monti, Lorenzo, Pedrotti, Patrizia, Vandenberk, Bert, Squeri, Angelo, Lombardi, Massimo, Ferreira, António M, Schwitter, Juerg, Aquaro, Giovanni Donato, Chiribiri, Amedeo, Rodríguez Palomares, José F, Yilmaz, Ali, Andreini, Daniele, Florian, Anca, Leiner, Tim, Abecasis, João, Badano, Luigi Paolo, Bogaert, Jan, and Masci, Pier-Giorgio

Published
2023

20. Acute heart failure in Yemen

Author

AL-Zendani, Aziz, Al-Emad, Adel, Al-Motarreb, Ahmed, Amen, Mervat, AL-Sagheer, Nora, Hadi, Hana Abu, Al-Wather, Nawar, AL-Fakeh, Hesham, Cimino, Sara, and Agati, Luciano

Published
2019
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21. Prognostic role of pre- and postinterventional myocardial injury in patients undergoing transcatheter aortic valve implantation

Author

FILOMENA, Domenico, primary, MONOSILIO, Sara, additional, CIMINO, Sara, additional, MAESTRINI, Viviana, additional, LUONGO, Federico, additional, NECCIA, Matteo, additional, SALVI, Nicolò, additional, COLANTONIO, Riccardo, additional, MANCONE, Massimo, additional, SARDELLA, Gennaro, additional, FEDELE, Francesco, additional, and AGATI, Luciano, additional

Published
2023
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22. Myocardial Fibrosis at Cardiac MRI Helps Predict Adverse Clinical Outcome in Patients with Mitral Valve Prolapse

Author

Figliozzi, Stefano, primary, Georgiopoulos, Georgios, additional, Lopes, Pedro M., additional, Bauer, Klemens B., additional, Moura-Ferreira, Sara, additional, Tondi, Lara, additional, Mushtaq, Saima, additional, Censi, Stefano, additional, Pavon, Anna Giulia, additional, Bassi, Ilaria, additional, Servato, Maria Luz, additional, Teske, Arco J., additional, Biondi, Federico, additional, Filomena, Domenico, additional, Pica, Silvia, additional, Torlasco, Camilla, additional, Muraru, Denisa, additional, Monney, Pierre, additional, Quattrocchi, Giuseppina, additional, Maestrini, Viviana, additional, Agati, Luciano, additional, Monti, Lorenzo, additional, Pedrotti, Patrizia, additional, Vandenberk, Bert, additional, Squeri, Angelo, additional, Lombardi, Massimo, additional, Ferreira, António M., additional, Schwitter, Juerg, additional, Aquaro, Giovanni Donato, additional, Chiribiri, Amedeo, additional, Rodríguez Palomares, José F., additional, Yilmaz, Ali, additional, Andreini, Daniele, additional, Florian, Anca, additional, Leiner, Tim, additional, Abecasis, João, additional, Badano, Luigi Paolo, additional, Bogaert, Jan, additional, and Masci, Pier-Giorgio, additional

Published
2023
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25. AC-Mode of Chemotherapy as a Trigger of Cardiac Syndrome X: A Case Study

Author

Avagimyan, Ashot, primary, Mkrtchyan, Lusine, additional, Abrahomovich, Orest, additional, Sheibani, Mohammad, additional, Guevorkyan, Astkhik, additional, Sarrafzadegan, Nizal, additional, Kozhukhov, Sergey, additional, Agati, Luciano, additional, Astengiano, Ricardo, additional, Zaritska, Valentina, additional, and Jndoyan, Zinaida, additional

Published
2022
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29. Comparison of Sulfur Hexafluoride Microbubble (SonoVue)-Enhanced Myocardial Contrast Echocardiography With Gated Single-Photon Emission Computed Tomography for Detection of Significant Coronary Artery Disease: A Large European Multicenter Study

Author

Senior, Roxy, Moreo, Antonella, Gaibazzi, Nicola, Agati, Luciano, Tiemann, Klaus, Shivalkar, Bharati, von Bardeleben, Stephan, Galiuto, Leonarda, Lardoux, Hervé, Trocino, Giuseppe, Carrió, Ignasi, Le Guludec, Dominique, Sambuceti, Gianmario, Becher, Harald, Colonna, Paolo, ten Cate, Folkert, Bramucci, Ezio, Cohen, Ariel, Bezante, Gianpaolo, Aggeli, Costantina, and Kasprzak, Jaroslaw D.

Published
2013
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30. Clinical practice of contrast echocardiography: recommendation by the European Association of Cardiovascular Imaging (EACVI) 2017

Author

Senior, Roxy, Becher, Harald, Monaghan, Mark, Agati, Luciano, Zamorano, Jose, Vanoverschelde, Jean Louis, Nihoyannopoulos, Petros, Edvardsen, Thor, Lancellotti, Patrizio, Delgado, Victoria, Gimelli, Alessia, Cosyns, Bernard, Gerber, Bernhard, Donal, Erwan, Flachskampf, Frank, Haugaa, Kristina, Cardim, Nuno, and Masci, Pier Giorgio

Published
2017
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31. Cardiac and Vascular Remodeling After 6 Months of Therapy With Sacubitril/Valsartan: Mechanistic Insights From Advanced Echocardiographic Analysis

Author

Monosilio, Sara, primary, Filomena, Domenico, additional, Luongo, Federico, additional, Sannino, Michele, additional, Cimino, Sara, additional, Neccia, Matteo, additional, Mariani, Marco Valerio, additional, Birtolo, Lucia Ilaria, additional, Benedetti, Giulia, additional, Tonti, Giovanni, additional, Pedrizzetti, Gianni, additional, Vizza, Carmine Dario, additional, Maestrini, Viviana, additional, and Agati, Luciano, additional

Published
2022
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34. 3D Echo Characterization of Proportionate and Disproportionate Functional Mitral Regurgitation before and after Percutaneous Mitral Valve Repair

Author

Cimino, Sara, primary, Agati, Luciano, additional, Filomena, Domenico, additional, Maestrini, Viviana, additional, Monosilio, Sara, additional, Birtolo, Lucia Ilaria, additional, Mocci, Michele, additional, Mancone, Massimo, additional, Sardella, Gennaro, additional, Grayburn, Paul, additional, and Fedele, Francesco, additional

Published
2022
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35. Impact of intraventricular haemodynamic forces misalignment on left ventricular remodelling after myocardial infarction

Author

Filomena, Domenico, primary, Cimino, Sara, additional, Monosilio, Sara, additional, Galea, Nicola, additional, Mancuso, Giuseppe, additional, Francone, Marco, additional, Tonti, Giovanni, additional, Pedrizzetti, Gianni, additional, Maestrini, Viviana, additional, Fedele, Francesco, additional, and Agati, Luciano, additional

Published
2021
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36. 511 Cardio-vascular remodelling during sacubitril/valsartan therapy in patients with heart failure and reduced ejection fraction

Author

Monosilio, Sara, primary, Filomena, Domenico, additional, Luongo, Federico, additional, Neccia, Matteo, additional, Sannino, Michele, additional, Birtolo, Lucia Ilaria, additional, Cimino, Sara, additional, Benedetti, Giulia, additional, Tonti, Giovanni, additional, Pedrizzetti, Gianni, additional, Fedele, Francesco, additional, Maestrini, Viviana, additional, and Agati, Luciano, additional

Published
2021
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40. Thrombus Aspiration During Primary Percutaneous Coronary Intervention Improves Myocardial Reperfusion and Reduces Infarct Size: The EXPIRA (Thrombectomy With Export Catheter in Infarct-Related Artery During Primary Percutaneous Coronary Intervention) Prospective, Randomized Trial

Author

Sardella, Gennaro, Mancone, Massimo, Bucciarelli-Ducci, Chiara, Agati, Luciano, Scardala, Raffaele, Carbone, Iacopo, Francone, Marco, Di Roma, Angelo, Benedetti, Giulia, Conti, Giulia, and Fedele, Francesco

Published
2009
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43. Update on phase II studies of erythropoietin in acute myocardial infarction. Rationale and design of Exogenous erythroPoietin in Acute Myocardial Infarction: New Outlook aNd Dose Association Study (EPAMINONDAS)

Author

Andreotti, Felicita, Agati, Luciano, Conti, Elena, Santucci, Eleonora, Rio, Teresa, Tarantino, Federica, Natale, Luigi, Berardi, Daniele, Mattatelli, Antonella, Musumeci, Beatrice, Bonomo, Lorenzo, Volpe, Massimo, Crea, Filippo, and Autore, Camillo

Published
2009
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46. Does coronary angioplasty after timely thrombolysis improve microvascular perfusion and left ventricular function after acute myocardial infarction?

Author

Agati, Luciano, Funaro, Stefania, Madonna, Mariapina, Sardella, Gennaro, Garramone, Barbara, and Galiuto, Leonarda

Subjects
Angioplasty, Heart attack, Health
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ahj.2007.03.028 Byline: Luciano Agati (a), Stefania Funaro (b), Mariapina Madonna (a), Gennaro Sardella (a), Barbara Garramone (c), Leonarda Galiuto (c) Abstract: Recent data show that percutaneous coronary intervention (PCI) in patients with stable postthrombolytic ST-segment elevation myocardial infarction (STEMI) is better than no PCI or ischemia-guided PCI. These results still have to find a pathophysiologic explanation. We hypothesized that complete mechanical recanalization of infarct-related artery improves clinical benefits of thrombolysis as a result of more preserved and better perfused coronary microcirculation. To test this hypothesis, we studied a selected STEMI population presenting very early after symptom onset in whom successful infarct-related artery reperfusion was obtained by thrombolysis followed or not by elective PCI within 24 hours, and we compared these 2 groups with those underwent primary PCI. Author Affiliation: (a) Department of Cardiology, 'La Sapienza' University, Rome, Italy (b) Department of Cardiology, Catholic University, Campobasso, Italy (c) Institute of Cardiology, Catholic University, Rome, Italy Article History: Received 12 October 2006; Accepted 19 March 2007

Published
2007

47. Early or deferred cardiovascular magnetic resonance after ST-segment-elevation myocardial infarction for effective risk stratification

Author

Masci, P, Pavon, A, Pontone, G, Symons, R, Lorenzoni, V, Francone, M, Zalewski, J, Barison, A, Guglielmo, M, Aquaro, G, Galea, N, Muscogiuri, G, Muller, O, Carbone, I, Baggiano, A, Iglesias, J, Nessler, J, Andreini, D, Camici, P, Claus, P, Luca, L, Agati, L, Janssens, S, Schwitter, J, Bogaert, J, Masci, Pier Giorgio, Pavon, Anna Giulia, Pontone, Gianluca, Symons, Rolf, Lorenzoni, Valentina, Francone, Marco, Zalewski, Jaroslaw, Barison, Andrea, Guglielmo, Marco, Aquaro, Giovanni Donato, Galea, Nicola, Muscogiuri, Giuseppe, Muller, Olivier, Carbone, Iacopo, Baggiano, Andrea, Iglesias, Juan F, Nessler, Jadwiga, Andreini, Daniele, Camici, Paolo G, Claus, Piet, Luca, Laura de, Agati, Luciano, Janssens, Stefan, Schwitter, Jurg, Bogaert, Jan, Masci, P, Pavon, A, Pontone, G, Symons, R, Lorenzoni, V, Francone, M, Zalewski, J, Barison, A, Guglielmo, M, Aquaro, G, Galea, N, Muscogiuri, G, Muller, O, Carbone, I, Baggiano, A, Iglesias, J, Nessler, J, Andreini, D, Camici, P, Claus, P, Luca, L, Agati, L, Janssens, S, Schwitter, J, Bogaert, J, Masci, Pier Giorgio, Pavon, Anna Giulia, Pontone, Gianluca, Symons, Rolf, Lorenzoni, Valentina, Francone, Marco, Zalewski, Jaroslaw, Barison, Andrea, Guglielmo, Marco, Aquaro, Giovanni Donato, Galea, Nicola, Muscogiuri, Giuseppe, Muller, Olivier, Carbone, Iacopo, Baggiano, Andrea, Iglesias, Juan F, Nessler, Jadwiga, Andreini, Daniele, Camici, Paolo G, Claus, Piet, Luca, Laura de, Agati, Luciano, Janssens, Stefan, Schwitter, Jurg, and Bogaert, Jan

Abstract

Aims: In ST-segment-elevation myocardial infarction (STEMI), cardiovascular magnetic resonance (CMR) holds the potentiality to improve risk stratification in addition to Thrombolysis in Myocardial Infarction (TIMI) risk score. Nevertheless, the optimal timing for CMR after STEMI remains poorly defined. We aim at comparing the prognostic performance of three stratification strategies according to the timing of CMR after STEMI. Methods and results: The population of this prospective registry-based study included 492 reperfused STEMI patients. All patients underwent post-reperfusion (median: 4 days post-STEMI) and follow-up (median: 4.8 months post-STEMI) CMR. Left ventricular (LV) volumes, function, infarct size, and microvascular obstruction extent were quantified. Primary endpoint was a composite of all-death and heart failure (HF) hospitalization. Baseline-to-follow-up percentage increase of LV end-diastolic (EDV; DLV-EDV) =20% or end-systolic volumes (ESV; DLV-ESV) =15% were tested against outcome. Three multivariate models were developed including TIMI risk score plus early post-STEMI (early-CMR) or follow-up CMR (deferred-CMR) or both CMRs parameters along with adverse LV remodelling (paired-CMRs). During a median follow-up of 8.3 years, the primary endpoint occurred in 84 patients (47 deaths; 37 HF hospitalizations). Early-CMR, deferred-CMR, and paired-CMR demonstrated similar predictive value for the primary endpoint (C-statistic: 0.726, 0.728, and 0.738, respectively; P = 0.663). DLV-EDV =20% or DLV-ESV =15% were unadjusted outcome predictors (hazard ratio: 2.020 and 2.032, respectively; P = 0.002 for both) but lost their predictive value when corrected for other covariates in paired-CMR model. Conclusion: In STEMI patients, early-, deferred-, or paired-CMR were equivalent stratification strategies for outcome prediction. Adverse LV remodelling parameters were not independent prognosticators.

Published
2020

49. Hydroxychloroquine cardiotoxicity: a case-control study comparing patients with COVID-19 and patients with systemic lupus erythematosus

Author

Mancuso, Silvia, primary, Spinelli, Francesca Romana, additional, Agati, Luciano, additional, Ciardi, Maria Rosa, additional, Garufi, Cristina, additional, Natalucci, Francesco, additional, Molteni, Emanuele, additional, Truglia, Simona, additional, Riccieri, Valeria, additional, Priori, Roberta, additional, Mastroianni, Claudio Maria, additional, and Conti, Fabrizio, additional

Published
2021
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