1. Coronary sinus diameter to estimate congestion and predict survival
- Author
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Agatella Barchitta, Giacomo Rossitto, Luisa Ruzza, Daniele Maio, Giuseppe Scaparotta, Domenico Bagordo, Francesco Antonini Canterin, Piergiuseppe Piovesana, Teresa Maria Seccia, Federico Nalesso, Lorenzo Calò, and Gian Paolo Rossi
- Subjects
Echocardiography ,Congestion ,Coronary sinus ,Inferior vena cava ,Hemodialysis ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background: Congestion predicts a poor prognosis, but its assessment is challenging in clinical practice and requires a multiparametric approach. We investigated if the coronary sinus (CS) diameter can predict mortality in a human model of rapid fluid unloading. Methods: We measured by echocardiography the CS, and the inferior vena cava (IVC) for comparison, in 60 patients with end-stage chronic kidney disease (ESKD) immediately before and after hemodialysis (HD; age 76 [57–81] years, 40% female, left ventricular ejection fraction 57 [53–56]%). Patients were prospectively followed up for all-cause mortality. Results: HD-induced decongestion decreased the maximum diameters of both CS and IVC (p ≤ 0.001 for all). The maximum diameter of the CS (CSmax) was as accurate as the IVC maximum diameter and collapsibility for the identification of congestion, defined as pre-hemodialysis status (AUROC CSmax = 0.902 vs IVC = 0.895, p = n.s.). A CSmax diameter after hemodialysis > 9 mm predicted all-cause mortality at 12 months (Log-rank Chi square = 11.49, p
- Published
- 2023
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