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231 results on '"Agarwal, Prashant"'

4. Terror strikes courtyard

Author

Patahk, Manoj K., Chaturvedi, Rajesh, Agarwal, Prashant, Toshi, Senti, and Tripathi, S.K.

Published
2009

7. Outcomes of infants with hypoxic ischemic encephalopathy and persistent pulmonary hypertension of the newborn: results from three NICHD studies

Author

Agarwal, Prashant, Shankaran, Seetha, Laptook, Abbot R, Chowdhury, Dhuly, Lakshminrusimha, Satyan, Bonifacio, Sonia Lomeli, Natarajan, Girija, Chawla, Sanjay, Keszler, Martin, Heyne, Roy J, Ambalavanan, Namasivayam, Walsh, Michele C, Das, Abhik, and Van Meurs, Krisa P

Subjects
Paediatrics, Biomedical and Clinical Sciences, Infant Mortality, Pediatric, Clinical Trials and Supportive Activities, Clinical Research, Brain Disorders, Intellectual and Developmental Disabilities (IDD), Perinatal Period - Conditions Originating in Perinatal Period, Reproductive health and childbirth, Humans, Hypertension, Pulmonary, Hypothermia, Induced, Hypoxia-Ischemia, Brain, Infant, Infant, Newborn, National Institute of Child Health and Human Development (U.S.), Persistent Fetal Circulation Syndrome, United States, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Neonatal Research Network, Clinical Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo determine the association of persistent pulmonary hypertension of the newborn (PPHN) with death or disability among infants with moderate or severe hypoxic ischemic encephalopathy (HIE) treated with therapeutic hypothermia.MethodsWe compared infants with and without PPHN enrolled in the hypothermia arm from three randomized controlled trials (RCTs): Induced Hypothermia trial, "usual care" arm of Optimizing Cooling trial, and Late Hypothermia trial. Primary outcome was death or disability at 18-22 months adjusted for severity of HIE, center, and RCT.ResultsAmong 280 infants, 67 (24%) were diagnosed with PPHN. Among infants with and without PPHN, death or disability was 47% vs. 29% (adjusted OR: 1.65, 0.86-3.14) and death was 26% vs. 12% (adjusted OR: 2.04, 0.92-4.53), respectively.ConclusionsPPHN in infants with moderate or severe HIE was not associated with a statistically significant increase in primary outcome. These results should be interpreted with caution given the limited sample size.

Published
2021

8. Early-Life Outcomes in Relation to Social Determinants of Health for Children Born Extremely Preterm

Author

Jobe, Alan H., Caplan, Michael S., Polin, Richard A., Laptook, Abbot R., Keszler, Martin, Hensman, Angelita M., Alksninis, Barbara, Bishop, Carmena, Burke, Robert T., Caskey, Melinda, Hoffman, Laurie, Johnson, Katharine, Keszler, Mary Lenore, Knoll, Andrea M., Lamberson, Vita, Leach, Teresa M., Little, Emilee, McGowan, Elisabeth C., Stephens, Bonnie E., Vieira, Elisa, St. Pierre, Lucille, Ventura, Suzy, Watson, Victoria E., Hibbs, Anna Maria, Walsh, Michele C., Wilson-Costello, Deanne E., Newman, Nancy S., Bhola, Monika, Payne, Allison H., Siner, Bonnie S., Yalcinkaya, Gulgun, Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Scott, Allison, Parimi, Prabhu S., Gaetano, Lisa, Poindexter, Brenda B., Schibler, Kurt, Kallapur, Suhas G., Donovan, Edward F., Merhar, Stephanie, Grisby, Cathy, Yolton, Kimberly, Alexander, Barbara, Beiersdorfer, Traci, Bridges, Kate, Cahill, Tanya E., Dudley, Juanita, Fischer, Estelle E., Gratton, Teresa L., Hayes, Devan, Hessling, Jody, Jackson, Lenora D., Kirker, Kristin, Mincey, Holly L., Muthig, Greg, Stacey, Sara, Steichen, Jean J., Tepe, Stacey, Thompson, Julia, Wuertz, Sandra, Cotten, C. Michael, Goldberg, Ronald N., Goldstein, Ricki F., Malcolm, William F., Mago-Shah, Deesha, Ashley, Patricia L., Finkle, Joanne, Auten, Kathy J., Fisher, Kimberley A., Grimes, Sandra, Gustafson, Kathryn E., Lohmeyer, Melody B., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Bose, Gennie, Clark, Cindy, Talbert, Jennifer, Warner, Diane, Trembath, Andrea, O'Shea, T. Michael, Wereszczak, Janice, Kicklighter, Stephen D., Rhodes-Ryan, Ginger, White, Donna, Patel, Ravi M., Carlton, David P., Stoll, Barbara J., Hale, Ellen C., Loggins, Yvonne C., Adams-Chapman, Ira, Blackwelder, Ann, Bottcher, Diane I., Carter, Sheena L., Kendrick-Allwood, Salathiel, Laursen, Judith, LaRossa, Maureen Mulligan, Mackie, Colleen, Sanders, Amy, Seabrook, Irma, Smikle, Gloria, Wineski, Lynn C., Higgins, Rosemary D., Bremer, Andrew A., Archer, Stephanie Wilson, Sokol, Gregory M., Dusick, Anna M., Papile, Lu Ann, Gunn, Susan, Hamer, Faithe, Harmon, Heidi M., Herron, Dianne E., Hines, Abbey C., Lytle, Carolyn, Miller, Lucy C., Minnich, Heike M., Richard, Leslie, Smiley, Lucy, Wilson, Leslie Dawn, Tyson, Jon E., Kennedy, Kathleen A., Khan, Amir M., Duncan, Andrea, Mosquera, Ricardo, Stephens, Emily K., McDavid, Georgia E., Alaniz, Nora I., Allain, Elizabeth, Arldt-McAlister, Julie, Burson, Katrina, Dempsey, Allison G., Eason, Elizabeth, Evans, Patricia W., Garcia, Carmen, Green, Charles, Hall, Donna, Harris, Beverly Foley, Jiminez, Margarita, John, Janice, Jones, Patrick M., Lillie, M. Layne, Lis, Anna E., Martin, Karen, Martin, Sara C., Mason, Carrie M., McKee, Shannon, Morris, Brenda H., Rennie, Kimberly, Rodgers, Shawna, Siddiki, Saba Khan, Simmons, Maegan C., Sperry, Daniel, Pierce Tate, Patti L., Wright, Sharon L., Sánchez, Pablo J., Nelin, Leif D., Jadcherla, Sudarshan R., Slaughter, Jonathan L., Yeates, Keith O., Keim, Sarah, Maitre, Nathalie L., Timan, Christopher J., Luzader, Patricia, Clark, Erna, Fortney, Christine A., Gutentag, Julie, Park, Courtney, Shadd, Julie, Sullivan, Margaret, Stein, Melanie, Nelin, Mary Ann, Newton, Julia, Small, Kristi, Burkhardt, Stephanie, Purnell, Jessica, Pietruszewski, Lindsay, Levengood, Katelyn, Batterson, Nancy, Morehead, Pamela, Carey, Helen, Yoseff-Salameh, Lina, Sullivan, Rox Ann, Hague, Cole, Grothause, Jennifer, Fearns, Erin, Fowler, Aubrey, Notestine, Jennifer, Tonneman, Jill, Hay, Krystal, Chao, Michelle, Warnimont, Kyrstin, Marzec, Laura, Miller, Bethany, Beckford, Demi R., Baugher, Hallie, DeSantis, Brittany, Hanlon, Cory, McCool, Jacqueline, Das, Abhik, Gantz, Marie G., Bann, Carla M., Wallace, Dennis, Crawford, Margaret M., Gabrio, Jenna, Leblond, David, Newman, Jamie E., Petrie Huitema, Carolyn M., O'Donnell Auman, Jeanette, Poole, W. Kenneth, Zaterka-Baxter, Kristin M., Van Meurs, Krisa P., Chock, Valerie Y., Stevenson, David K., Adams, Marian M., Ball, M. Bethany, Bentley, Barbara, Bruno, Elizabeth, Davis, Alexis S., Elena DeAnda, Maria, DeBattista, Anne M., Huffman, Lynne C., Ismael, Magdy, Kohn, Jean G., Krueger, Casey, Lowe, Janice, Lucash, Ryan E., Palmquist, Andrew W., Patel, Jessica, Proud, Melinda S., Reichert, Elizabeth N., John, Nicholas H. St., Sivakumar, Dharshi, Taylor, Heather L., Wager, Natalie, Williams, R. Jordan, Weiss, Hali, Frantz, Ivan D., III, Fiascone, John M., MacKinnon, Brenda L., Furey, Anne, Nylen, Ellen, Church, Paige T., Sibley, Cecelia E., Brussa, Ana K., Carlo, Waldemar A., Ambalavanan, Namasivayam, Peralta-Carcelen, Myriam, Nelson, Kathleen G., Bailey, Kirstin J., Biasini, Fred J., Chopko, Stephanie A., Collins, Monica V., Cosby, Shirley S., Johnston, Kristen C., Moses, Mary Beth, Patterson, Cryshelle S., Phillips, Vivien A., Preskitt, Julie, Rector, Richard V., Whitley, Sally, Devaskar, Uday, Garg, Meena, Purdy, Isabell B., Chanlaw, Teresa, Geller, Rachel, Finer, Neil N., Vaucher, Yvonne E., Kaegi, David, Rasmussen, Maynard R., Arnell, Kathy, Demetrio, Clarence, Fuller, Martha G., Rich, Wade, Bell, Edward F., Colaizy, Tarah T., Widness, John A., Brumbaugh, Jane E., Acarregui, Michael J., Johnson, Karen J., Eastman, Diane L., Goeke, Claire A., Schmelzel, Mendi L., Walker, Jacky R., Baack, Michelle L., Hogden, Laurie A., Broadbent, Megan, Elenkiwich, Chelsey, Henning, Megan M., Van Muyden, Sarah, Ellsbury, Dan L., Campbell, Donia B., Tud, Tracy L., Duara, Shahnaz, Bauer, Charles R., Everett-Thomas, Ruth, Fajardo-Hiriart, Sylvia, Rigaud, Arielle, Calejo, Maria, Frade Eguaras, Silvia M., Berkowits, Michelle Harwood, Garcia, Andrea, Pierre, Helina, Stoerger, Alexandra, Watterberg, Kristi L., Fuller, Janell, Ohls, Robin K., Beauman, Sandra Sundquist, Lacy, Conra Backstrom, Duncan, Andrea F., Hanson, Mary, Hartenberger, Carol, Kuan, Elizabeth, Lowe, Jean R., Thomson, Rebecca A., DeMauro, Sara B., Eichenwald, Eric C., Schmidt, Barbara, Kirpalani, Haresh, Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Catts, Christine, Cook, Noah, Cucinotta, Dara M., Bernbaum, Judy C., Gerdes, Marsha, Ghavam, Sarvin, Hurt, Hallam, Snyder, Jonathan, Vangala, Saritha, Ziolkowski, Kristina, D'Angio, Carl T., Phelps, Dale L., Guillet, Ronnie, Myers, Gary J., Andrews-Hartley, Michelle, Johnson, Julie Babish, Binion, Kyle, Bowman, Melissa, Boylin, Elizabeth, Burnell, Erica, Coleman, Kelly R., Fallone, Cait, Farooq, Osman, Hunn, Julianne, Hust, Diane, Jensen, Rosemary L., Jones, Rachel, Kachelmeyer, Jennifer, Kushner, Emily, Maffett, Deanna, McKee, Kimberly G., Merzbach, Joan, Orme, Constance, Prinzing, Diane, Reubens, Linda J., Rochez, Daisy, Rowan, Mary, Sabaratnam, Premini, Scorsone, Ann Marie, Wadkins, Holly I.M., Yost, Kelley, Zwetsch, Lauren, Lakshminrusimha, Satyan, Reynolds, Anne Marie, Sacilowski, Michael G., Guilford, Stephanie, Li, Emily, Williams, Ashley, Zorn, William A., Wyckoff, Myra H., Brion, Luc P., Salhab, Walid A., Rosenfeld, Charles R., Heyne, Roy J., Vasil, Diana M., Adams, Sally S., Chen, Lijun, De Leon, Maria M., Eubanks, Francis, Guzman, Alicia, Hensley, Gaynelle, Heyne, Elizabeth T., Lee, Lizette E., Leps, Melissa H., Madden, Linda A., McDougald, E. Rebecca, Miller, Nancy A., Morgan, Janet S., Pavageau, Lara, Sepulveda, Pollieanna, Tolentino-Plata, Kristine, Boatman, Cathy Twell, Vera, Azucena, Waterbury, Jillian, Yoder, Bradley A., Baserga, Mariana, Faix, Roger G., Winter, Sarah, Minton, Stephen D., Sheffield, Mark J., Rau, Carrie A., Baker, Shawna, Bird, Karie, Burnett, Jill, Christensen, Susan, Cole-Bledsoe, Laura, Davis, Brandy, Elmont, Jennifer O., Jensen, Jennifer J., Loertscher, Manndi C., Jordan, Jamie, Marchant, Trisha, Maxson, Earl, McGrath, Kandace M., Osborne, Karen A., Parry, D. Melody, Reich, Brixen A., Schaefer, Susan T., Spencer, Cynthia, Steffen, Michael, Tice, Katherine, Weaver-Lewis, Kimberlee, Woodbury, Kathryn D., Zanetti, Karen, Dillard, Robert G., Washburn, Lisa K., Jackson, Barbara G., Peters, Nancy, Chiu, Korinne, Allred, Deborah Evans, Goldstein, Donald J., Halfond, Raquel, Peterson, Carroll, Waldrep, Ellen L., Welch, Cherrie D., Morris, Melissa Whalen, Hounshell, Gail Wiley, Shankaran, Seetha, Sood, Beena G., Natarajan, Girija, Pappas, Athina, Abramczyk, Katherine, Agarwal, Prashant, Bajaj, Monika, Bara, Rebecca, Billian, Elizabeth, Chawla, Sanjay, Childs, Kirsten, De Jesus, Lilia C., Driscoll, Debra, February, Melissa, Goldston, Laura A., Johnson, Mary E., Muran, Geraldine, Panaitescu, Bogdan, Prentiss, Jeannette E., White, Diane, Woldt, Eunice, Barks, John, Wiggins, Stephanie A., Christensen, Mary K., Carlson, Martha D., Ehrenkranz, Richard A., Jacobs, Harris, Butler, Christine G., Cervone, Patricia, Greisman, Sheila, Konstantino, Monica, Poulsen, JoAnn, Taft, Janet, Williams, Joanne, Romano, Elaine, Vohr, Betty R., Travers, Colm P., and Hintz, Susan R.

Published
2023
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10. Venovenous versus venoarterial extracorporeal membrane oxygenation among infants with hypoxic-ischemic encephalopathy: is there a difference in outcome?

Author

Agarwal, Prashant, Natarajan, Girija, Sullivan, Kevin, Rao, Rakesh, Rintoul, Natalie, Zaniletti, Isabella, Keene, Sarah, Mietzsch, Ulrike, Massaro, An N., Billimoria, Zeenia, Dirnberger, Daniel, Hamrick, Shannon, Seabrook, Ruth B., Weems, Mark F., Cleary, John P., Gray, Brian W., and DiGeronimo, Robert

Published
2021
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14. Enabling Real Time Analytics over Raw XML Data

Author

Agarwal, Manoj K., Ramamritham, Krithi, Agarwal, Prashant, van der Aalst, Wil, Series Editor, Mylopoulos, John, Series Editor, Rosemann, Michael, Series Editor, Shaw, Michael J., Series Editor, Szyperski, Clemens, Series Editor, Castellanos, Malu, editor, Chrysanthis, Panos K., editor, and Pelechrinis, Konstantinos, editor

Published
2019
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18. Wireless Monitoring and Indoor Navigation of a Mobile Robot Using RFID

Author

Agarwal, Prashant, Gupta, Aman, Verma, Gaurav, Verma, Himanshu, Sharma, Ashish, Banarwal, Sandeep, Kacprzyk, Janusz, Series editor, Pal, Nikhil R., Advisory editor, Bello Perez, Rafael, Advisory editor, Corchado, Emilio S., Advisory editor, Hagras, Hani, Advisory editor, Kóczy, László T., Advisory editor, Kreinovich, Vladik, Advisory editor, Lin, Chin-Teng, Advisory editor, Lu, Jie, Advisory editor, Melin, Patricia, Advisory editor, Nedjah, Nadia, Advisory editor, Nguyen, Ngoc Thanh, Advisory editor, Wang, Jun, Advisory editor, Panigrahi, Bijaya Ketan, editor, Hoda, M. N., editor, Sharma, Vinod, editor, and Goel, Shivendra, editor

Published
2018
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19. Early-Life Outcomes in Relation to Social Determinants of Health for Children Born Extremely Preterm

Author

Brumbaugh, Jane E., primary, Vohr, Betty R., additional, Bell, Edward F., additional, Bann, Carla M., additional, Travers, Colm P., additional, McGowan, Elisabeth C., additional, Harmon, Heidi M., additional, Carlo, Waldemar A., additional, Duncan, Andrea F., additional, Hintz, Susan R., additional, Jobe, Alan H., additional, Caplan, Michael S., additional, Polin, Richard A., additional, Laptook, Abbot R., additional, Keszler, Martin, additional, Hensman, Angelita M., additional, Alksninis, Barbara, additional, Bishop, Carmena, additional, Burke, Robert T., additional, Caskey, Melinda, additional, Hoffman, Laurie, additional, Johnson, Katharine, additional, Keszler, Mary Lenore, additional, Knoll, Andrea M., additional, Lamberson, Vita, additional, Leach, Teresa M., additional, Little, Emilee, additional, Stephens, Bonnie E., additional, Vieira, Elisa, additional, St. Pierre, Lucille, additional, Ventura, Suzy, additional, Watson, Victoria E., additional, Hibbs, Anna Maria, additional, Walsh, Michele C., additional, Wilson-Costello, Deanne E., additional, Newman, Nancy S., additional, Bhola, Monika, additional, Payne, Allison H., additional, Siner, Bonnie S., additional, Yalcinkaya, Gulgun, additional, Truog, William E., additional, Pallotto, Eugenia K., additional, Kilbride, Howard W., additional, Gauldin, Cheri, additional, Holmes, Anne, additional, Johnson, Kathy, additional, Scott, Allison, additional, Parimi, Prabhu S., additional, Gaetano, Lisa, additional, Poindexter, Brenda B., additional, Schibler, Kurt, additional, Kallapur, Suhas G., additional, Donovan, Edward F., additional, Merhar, Stephanie, additional, Grisby, Cathy, additional, Yolton, Kimberly, additional, Alexander, Barbara, additional, Beiersdorfer, Traci, additional, Bridges, Kate, additional, Cahill, Tanya E., additional, Dudley, Juanita, additional, Fischer, Estelle E., additional, Gratton, Teresa L., additional, Hayes, Devan, additional, Hessling, Jody, additional, Jackson, Lenora D., additional, Kirker, Kristin, additional, Mincey, Holly L., additional, Muthig, Greg, additional, Stacey, Sara, additional, Steichen, Jean J., additional, Tepe, Stacey, additional, Thompson, Julia, additional, Wuertz, Sandra, additional, Cotten, C. Michael, additional, Goldberg, Ronald N., additional, Goldstein, Ricki F., additional, Malcolm, William F., additional, Mago-Shah, Deesha, additional, Ashley, Patricia L., additional, Finkle, Joanne, additional, Auten, Kathy J., additional, Fisher, Kimberley A., additional, Grimes, Sandra, additional, Gustafson, Kathryn E., additional, Lohmeyer, Melody B., additional, Laughon, Matthew M., additional, Bose, Carl L., additional, Bernhardt, Janice, additional, Bose, Gennie, additional, Clark, Cindy, additional, Talbert, Jennifer, additional, Warner, Diane, additional, Trembath, Andrea, additional, O'Shea, T. Michael, additional, Wereszczak, Janice, additional, Kicklighter, Stephen D., additional, Rhodes-Ryan, Ginger, additional, White, Donna, additional, Patel, Ravi M., additional, Carlton, David P., additional, Stoll, Barbara J., additional, Hale, Ellen C., additional, Loggins, Yvonne C., additional, Adams-Chapman, Ira, additional, Blackwelder, Ann, additional, Bottcher, Diane I., additional, Carter, Sheena L., additional, Kendrick-Allwood, Salathiel, additional, Laursen, Judith, additional, LaRossa, Maureen Mulligan, additional, Mackie, Colleen, additional, Sanders, Amy, additional, Seabrook, Irma, additional, Smikle, Gloria, additional, Wineski, Lynn C., additional, Higgins, Rosemary D., additional, Bremer, Andrew A., additional, Archer, Stephanie Wilson, additional, Sokol, Gregory M., additional, Dusick, Anna M., additional, Papile, Lu Ann, additional, Gunn, Susan, additional, Hamer, Faithe, additional, Herron, Dianne E., additional, Hines, Abbey C., additional, Lytle, Carolyn, additional, Miller, Lucy C., additional, Minnich, Heike M., additional, Richard, Leslie, additional, Smiley, Lucy, additional, Wilson, Leslie Dawn, additional, Tyson, Jon E., additional, Kennedy, Kathleen A., additional, Khan, Amir M., additional, Duncan, Andrea, additional, Mosquera, Ricardo, additional, Stephens, Emily K., additional, McDavid, Georgia E., additional, Alaniz, Nora I., additional, Allain, Elizabeth, additional, Arldt-McAlister, Julie, additional, Burson, Katrina, additional, Dempsey, Allison G., additional, Eason, Elizabeth, additional, Evans, Patricia W., additional, Garcia, Carmen, additional, Green, Charles, additional, Hall, Donna, additional, Harris, Beverly Foley, additional, Jiminez, Margarita, additional, John, Janice, additional, Jones, Patrick M., additional, Lillie, M. Layne, additional, Lis, Anna E., additional, Martin, Karen, additional, Martin, Sara C., additional, Mason, Carrie M., additional, McKee, Shannon, additional, Morris, Brenda H., additional, Rennie, Kimberly, additional, Rodgers, Shawna, additional, Siddiki, Saba Khan, additional, Simmons, Maegan C., additional, Sperry, Daniel, additional, Pierce Tate, Patti L., additional, Wright, Sharon L., additional, Sánchez, Pablo J., additional, Nelin, Leif D., additional, Jadcherla, Sudarshan R., additional, Slaughter, Jonathan L., additional, Yeates, Keith O., additional, Keim, Sarah, additional, Maitre, Nathalie L., additional, Timan, Christopher J., additional, Luzader, Patricia, additional, Clark, Erna, additional, Fortney, Christine A., additional, Gutentag, Julie, additional, Park, Courtney, additional, Shadd, Julie, additional, Sullivan, Margaret, additional, Stein, Melanie, additional, Nelin, Mary Ann, additional, Newton, Julia, additional, Small, Kristi, additional, Burkhardt, Stephanie, additional, Purnell, Jessica, additional, Pietruszewski, Lindsay, additional, Levengood, Katelyn, additional, Batterson, Nancy, additional, Morehead, Pamela, additional, Carey, Helen, additional, Yoseff-Salameh, Lina, additional, Sullivan, Rox Ann, additional, Hague, Cole, additional, Grothause, Jennifer, additional, Fearns, Erin, additional, Fowler, Aubrey, additional, Notestine, Jennifer, additional, Tonneman, Jill, additional, Hay, Krystal, additional, Chao, Michelle, additional, Warnimont, Kyrstin, additional, Marzec, Laura, additional, Miller, Bethany, additional, Beckford, Demi R., additional, Baugher, Hallie, additional, DeSantis, Brittany, additional, Hanlon, Cory, additional, McCool, Jacqueline, additional, Das, Abhik, additional, Gantz, Marie G., additional, Wallace, Dennis, additional, Crawford, Margaret M., additional, Gabrio, Jenna, additional, Leblond, David, additional, Newman, Jamie E., additional, Petrie Huitema, Carolyn M., additional, O'Donnell Auman, Jeanette, additional, Poole, W. Kenneth, additional, Zaterka-Baxter, Kristin M., additional, Van Meurs, Krisa P., additional, Chock, Valerie Y., additional, Stevenson, David K., additional, Adams, Marian M., additional, Ball, M. Bethany, additional, Bentley, Barbara, additional, Bruno, Elizabeth, additional, Davis, Alexis S., additional, Elena DeAnda, Maria, additional, DeBattista, Anne M., additional, Huffman, Lynne C., additional, Ismael, Magdy, additional, Kohn, Jean G., additional, Krueger, Casey, additional, Lowe, Janice, additional, Lucash, Ryan E., additional, Palmquist, Andrew W., additional, Patel, Jessica, additional, Proud, Melinda S., additional, Reichert, Elizabeth N., additional, John, Nicholas H. St., additional, Sivakumar, Dharshi, additional, Taylor, Heather L., additional, Wager, Natalie, additional, Williams, R. Jordan, additional, Weiss, Hali, additional, Frantz, Ivan D., additional, Fiascone, John M., additional, MacKinnon, Brenda L., additional, Furey, Anne, additional, Nylen, Ellen, additional, Church, Paige T., additional, Sibley, Cecelia E., additional, Brussa, Ana K., additional, Ambalavanan, Namasivayam, additional, Peralta-Carcelen, Myriam, additional, Nelson, Kathleen G., additional, Bailey, Kirstin J., additional, Biasini, Fred J., additional, Chopko, Stephanie A., additional, Collins, Monica V., additional, Cosby, Shirley S., additional, Johnston, Kristen C., additional, Moses, Mary Beth, additional, Patterson, Cryshelle S., additional, Phillips, Vivien A., additional, Preskitt, Julie, additional, Rector, Richard V., additional, Whitley, Sally, additional, Devaskar, Uday, additional, Garg, Meena, additional, Purdy, Isabell B., additional, Chanlaw, Teresa, additional, Geller, Rachel, additional, Finer, Neil N., additional, Vaucher, Yvonne E., additional, Kaegi, David, additional, Rasmussen, Maynard R., additional, Arnell, Kathy, additional, Demetrio, Clarence, additional, Fuller, Martha G., additional, Rich, Wade, additional, Colaizy, Tarah T., additional, Widness, John A., additional, Brumbaugh, Jane E., additional, Acarregui, Michael J., additional, Johnson, Karen J., additional, Eastman, Diane L., additional, Goeke, Claire A., additional, Schmelzel, Mendi L., additional, Walker, Jacky R., additional, Baack, Michelle L., additional, Hogden, Laurie A., additional, Broadbent, Megan, additional, Elenkiwich, Chelsey, additional, Henning, Megan M., additional, Van Muyden, Sarah, additional, Ellsbury, Dan L., additional, Campbell, Donia B., additional, Tud, Tracy L., additional, Duara, Shahnaz, additional, Bauer, Charles R., additional, Everett-Thomas, Ruth, additional, Fajardo-Hiriart, Sylvia, additional, Rigaud, Arielle, additional, Calejo, Maria, additional, Frade Eguaras, Silvia M., additional, Berkowits, Michelle Harwood, additional, Garcia, Andrea, additional, Pierre, Helina, additional, Stoerger, Alexandra, additional, Watterberg, Kristi L., additional, Fuller, Janell, additional, Ohls, Robin K., additional, Beauman, Sandra Sundquist, additional, Lacy, Conra Backstrom, additional, Hanson, Mary, additional, Hartenberger, Carol, additional, Kuan, Elizabeth, additional, Lowe, Jean R., additional, Thomson, Rebecca A., additional, DeMauro, Sara B., additional, Eichenwald, Eric C., additional, Schmidt, Barbara, additional, Kirpalani, Haresh, additional, Chaudhary, Aasma S., additional, Abbasi, Soraya, additional, Mancini, Toni, additional, Catts, Christine, additional, Cook, Noah, additional, Cucinotta, Dara M., additional, Bernbaum, Judy C., additional, Gerdes, Marsha, additional, Ghavam, Sarvin, additional, Hurt, Hallam, additional, Snyder, Jonathan, additional, Vangala, Saritha, additional, Ziolkowski, Kristina, additional, D'Angio, Carl T., additional, Phelps, Dale L., additional, Guillet, Ronnie, additional, Myers, Gary J., additional, Andrews-Hartley, Michelle, additional, Johnson, Julie Babish, additional, Binion, Kyle, additional, Bowman, Melissa, additional, Boylin, Elizabeth, additional, Burnell, Erica, additional, Coleman, Kelly R., additional, Fallone, Cait, additional, Farooq, Osman, additional, Hunn, Julianne, additional, Hust, Diane, additional, Jensen, Rosemary L., additional, Jones, Rachel, additional, Kachelmeyer, Jennifer, additional, Kushner, Emily, additional, Maffett, Deanna, additional, McKee, Kimberly G., additional, Merzbach, Joan, additional, Orme, Constance, additional, Prinzing, Diane, additional, Reubens, Linda J., additional, Rochez, Daisy, additional, Rowan, Mary, additional, Sabaratnam, Premini, additional, Scorsone, Ann Marie, additional, Wadkins, Holly I.M., additional, Yost, Kelley, additional, Zwetsch, Lauren, additional, Lakshminrusimha, Satyan, additional, Reynolds, Anne Marie, additional, Sacilowski, Michael G., additional, Guilford, Stephanie, additional, Li, Emily, additional, Williams, Ashley, additional, Zorn, William A., additional, Wyckoff, Myra H., additional, Brion, Luc P., additional, Salhab, Walid A., additional, Rosenfeld, Charles R., additional, Heyne, Roy J., additional, Vasil, Diana M., additional, Adams, Sally S., additional, Chen, Lijun, additional, De Leon, Maria M., additional, Eubanks, Francis, additional, Guzman, Alicia, additional, Hensley, Gaynelle, additional, Heyne, Elizabeth T., additional, Lee, Lizette E., additional, Leps, Melissa H., additional, Madden, Linda A., additional, McDougald, E. Rebecca, additional, Miller, Nancy A., additional, Morgan, Janet S., additional, Pavageau, Lara, additional, Sepulveda, Pollieanna, additional, Tolentino-Plata, Kristine, additional, Boatman, Cathy Twell, additional, Vera, Azucena, additional, Waterbury, Jillian, additional, Yoder, Bradley A., additional, Baserga, Mariana, additional, Faix, Roger G., additional, Winter, Sarah, additional, Minton, Stephen D., additional, Sheffield, Mark J., additional, Rau, Carrie A., additional, Baker, Shawna, additional, Bird, Karie, additional, Burnett, Jill, additional, Christensen, Susan, additional, Cole-Bledsoe, Laura, additional, Davis, Brandy, additional, Elmont, Jennifer O., additional, Jensen, Jennifer J., additional, Loertscher, Manndi C., additional, Jordan, Jamie, additional, Marchant, Trisha, additional, Maxson, Earl, additional, McGrath, Kandace M., additional, Osborne, Karen A., additional, Parry, D. Melody, additional, Reich, Brixen A., additional, Schaefer, Susan T., additional, Spencer, Cynthia, additional, Steffen, Michael, additional, Tice, Katherine, additional, Weaver-Lewis, Kimberlee, additional, Woodbury, Kathryn D., additional, Zanetti, Karen, additional, Dillard, Robert G., additional, Washburn, Lisa K., additional, Jackson, Barbara G., additional, Peters, Nancy, additional, Chiu, Korinne, additional, Allred, Deborah Evans, additional, Goldstein, Donald J., additional, Halfond, Raquel, additional, Peterson, Carroll, additional, Waldrep, Ellen L., additional, Welch, Cherrie D., additional, Morris, Melissa Whalen, additional, Hounshell, Gail Wiley, additional, Shankaran, Seetha, additional, Sood, Beena G., additional, Natarajan, Girija, additional, Pappas, Athina, additional, Abramczyk, Katherine, additional, Agarwal, Prashant, additional, Bajaj, Monika, additional, Bara, Rebecca, additional, Billian, Elizabeth, additional, Chawla, Sanjay, additional, Childs, Kirsten, additional, De Jesus, Lilia C., additional, Driscoll, Debra, additional, February, Melissa, additional, Goldston, Laura A., additional, Johnson, Mary E., additional, Muran, Geraldine, additional, Panaitescu, Bogdan, additional, Prentiss, Jeannette E., additional, White, Diane, additional, Woldt, Eunice, additional, Barks, John, additional, Wiggins, Stephanie A., additional, Christensen, Mary K., additional, Carlson, Martha D., additional, Ehrenkranz, Richard A., additional, Jacobs, Harris, additional, Butler, Christine G., additional, Cervone, Patricia, additional, Greisman, Sheila, additional, Konstantino, Monica, additional, Poulsen, JoAnn, additional, Taft, Janet, additional, Williams, Joanne, additional, and Romano, Elaine, additional

Published
2023
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22. Preparing Distribution Utilities for the Future - Evolving Customer Consumption in Renewable Rich Grids: A Novel Analytical Framework

Author

Nagarajan, Adarsh, primary, Ghosh, Shibani, additional, Duwadi, Kapil, additional, Schwarz, Marty, additional, Bryce, Richard, additional, Chernyakhovskiy, Ilya, additional, Palchak, David, additional, Nalwaya, Jitendra, additional, Dadhich, Mukesh, additional, Agarwal, Prashant, additional, and Sharma, Manu, additional

Published
2021
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24. Venovenous versus venoarterial extracorporeal membrane oxygenation among infants with hypoxic-ischemic encephalopathy: is there a difference in outcome?

Author

Agarwal, Prashant, Natarajan, Girija, Sullivan, Kevin, Rao, Rakesh, Rintoul, Natalie, Zaniletti, Isabella, Keene, Sarah, Mietzsch, Ulrike, Massaro, An N., Billimoria, Zeenia, Dirnberger, Daniel, Hamrick, Shannon, Seabrook, Ruth B., Weems, Mark F., Cleary, John P., Gray, Brian W., and DiGeronimo, Robert

Abstract

Objective: Our hypothesis was that among infants with hypoxic-ischemic encephalopathy (HIE), venoarterial (VA), compared to venovenous (VV), extracorporeal membrane oxygenation (ECMO) is associated with an increased risk of mortality or intracranial hemorrhage (ICH). Design/methods: Retrospective cohort analysis of infants in the Children’s Hospitals Neonatal Database from 2010 to 2016 with moderate or severe HIE, gestational age ≥36 weeks, and ECMO initiation <7 days of age. The primary outcome was mortality or ICH. Results: Severe HIE was more common in the VA ECMO group (n= 57), compared to the VV ECMO group (n= 53) (47.4% vs. 26.4%, P= 0.02). VA ECMO was associated with a significantly higher risk of death or ICH [57.9% vs. 34.0%, aOR 2.39 (1.08–5.28)] and mortality [31.6% vs. 11.3%, aOR 3.06 (1.08–8.68)], after adjusting for HIE severity. Conclusions: In HIE, VA ECMO was associated with a higher incidence of mortality or ICH. VV ECMO may be beneficial in this population.

Published
2024
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28. A study on IoT-based smart hospital system.

Author

Kumar, Rakesh, Agarwal, Prashant, Panda, Sampurna, and Gupta, Sunil Kumar

Subjects
*HOSPITALS, *DISTRIBUTED computing, *ARTIFICIAL intelligence, *INTERNET of things, *INFRASTRUCTURE (Economics)
Abstract

Digitalization in the healthcare industry has resulted in "smart hospitals" based on Internet of Things (IoT), data analytics, personalised services, and artificial intelligence (AI). Using distributed computing and information sharing, the Internet of Things (IoT) can instantly respond to system demands across a vast distributed network using distributed computing and IoT. I can't believe how fast it's going up! For example, smart gadgets like smartphones and light bulbs can be connected to the Internet using existing network infrastructure to improve patient care while simultaneously enhancing the efficiency of hospital resources. Digitally built IoT applications can access this network. Since it is intelligent, Internet of Things (IoT) technology also has the potential to improve service quality (QoS). If you have all the information you need, you can get an answer faster and with greater accuracy. This network can accept data from a number of sources, process it locally using modest computer power, or process it centrally utilising higher digital computing resources for superior decision-making skills. Predictive analysis, making intelligent recommendations, and looking for patterns are all viable uses for the information in this page. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Does Severity of Brain Injury on Magnetic Resonance Imaging Predict Short-Term Outcome in Neonates Who Received Therapeutic Hypothermia?

Author

Bhagat, Indira, Agarwal, Prashant, Sarkar, Avishek, Dechert, Ronald, Altinok, Deniz, and Chouthai, Nitin

Subjects
*BIOMARKERS, *EVALUATION of medical care, *LENGTH of stay in hospitals, *MULTIVARIATE analysis, *MULTIPLE regression analysis, *MAGNETIC resonance imaging, *RETROSPECTIVE studies, *ACQUISITION of data, *SEVERITY of illness index, *HYPOTHERMIA, *MEDICAL records, *DESCRIPTIVE statistics, *BRAIN injuries, *APGAR score
Abstract

Objective The National Institute of Child Health and Human Development (NICHD) magnetic resonance imaging (MRI) pattern of brain injury is a known biomarker of childhood outcome following therapeutic hypothermia for neonatal hypoxic–ischemic encephalopathy (HIE). However, usefulness of this classification has not been evaluated to predict short-term outcomes. The study aimed to test the hypothesis that infants with NICHD MRI pattern of severe hypoxic–ischemic brain injury will be sicker with more severe asphyxia-induced multiorgan dysfunction resulting in prolonged length of stay (LOS) following therapeutic hypothermia. We also evaluated the role of other risk factors which may prolong LOS. Study Design We retrospectively reviewed the medical records of 71 consecutively cooled neonates to examine the ability of MRI patterns of brain injury to predict the LOS. A neuroradiologist masked to outcomes classified the patterns of brain injury on MRI as per NICHD. Pattern 2A (basal ganglia thalamic, internal capsule, or watershed infarction), 2B (2A with cerebral lesions), and 3 (hemispheric devastation) of brain injury was deemed "severe injury." Results Out of 71 infants, 59 surviving infants had both MRI and LOS data. LOS was higher for infants who had Apgar's score of ≤5 at 10 minutes, severe HIE, seizures, coagulopathy, or needed vasopressors or inhaled nitric oxide, or had persistent feeding difficulty, or remained intubated following cooling. However, median LOS did not differ between the infants with and without MRI pattern of severe injury (15 days, interquartile range [IQR]: 9–28 vs. 12 days, IQR: 10–20; p = 0.4294). On multivariate linear regression analysis, only persistent feeding difficulty (β coefficient = 11, p = 0.001; or LOS = 11 days longer if had feeding difficulty) and ventilator days (β coefficient 1.7, p < 0.001; or LOS increased 1.7 times for each day of ventilator support) but not the severity of brain injury predicted LOS. Conclusion Unlike neurodevelopmental outcome, LOS is not related to severity of brain injury as defined by the NICHD. Key Points The NICHD pattern of brain injury on MRI predicts neurodevelopmental outcome following hypothermia treatment for neonatal HIE. LOS did not differ between the infants with and without MRI patterns of severe injury. The severity of brain injury as defined by the NICHD was not predictive of the LOS following therapeutic hypothermia. [ABSTRACT FROM AUTHOR]

Published
2023
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36. CMC development of [14C]-labeled sotorasib for the conduct of microtracer human ADME study.

Author

Sharma, Sonika, Agarwal, Prashant, Parsons, Andrew T., Huckle, James E., and Correll, Tiffany L.

Subjects
ACCELERATOR mass spectrometry, NON-small-cell lung carcinoma, HUMAN experimentation, DRUG labeling, OCHRATOXINS
Abstract

Human absorption, distribution, metabolism, and excretion (hADME) studies of new drugs are required for global regulatory filings. Recent advances in high sensitivity analytical technologies have enabled microtracer hADME studies wherein very low radioactive doses can be administered to healthy volunteers to study drug pharmacokinetic profile. Microtracer hADME studies are advantageous to accelerate study timelines during drug development. However, there are limited examples in peer-reviewed journals that highlight the key chemistry, manufacturing, and control (CMC) development challenges and requirements for enabling these clinical microtracer hADME studies. The current manuscript summarizes the CMC activities, risk assessment, and mitigation strategies that were put in place and executed to enable and accelerate the microtracer hADME study of [14C]-labeled sotorasib (AMG 510, compound 1). Sotorasib is a first in class KRASG12C inhibitor used to treat non-small cell lung cancer (NSCLC) in patients with a KRASG12Cmutation (Canon et al., Nature 575:217–223, 2019). The key CMC activities included the synthesis of low nanocurie [14C]-labeled AMG 510 drug substance, development of a drug-in-bottle (DIB) formulation, use of simulation software to predict absorption profiles, associated drug substance and drug product analytical control strategies development, and the utilization of accelerator mass spectrometry (AMS) as a CMC tool enabling low radioactive strength formulation analysis. [ABSTRACT FROM AUTHOR]

Published
2023
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39. Tofacitinib in the Management of Alopecia Universalis.

Author

Agarwal, Prashant

Subjects
*BALDNESS, *KINASE inhibitors, *CLOBETASOL, *TREATMENT effectiveness, *MINOXIDIL, *ALOPECIA areata
Abstract

Alopecia universalis (AU) is a rare form of hair loss characterized by the complete absence of hair on the scalp and body. It is an advanced form of alopecia areata. There is currently no definitive treatment for this condition, and management options are limited. This case report describes the successful treatment of a 37-year-old female patient with AU using oral tofacitinib 5 mg BID, an oral Janus kinase inhibitor. The patient experienced clinically significant hair regrowth on the scalp and eyebrows after 6 months of treatment with tofacitinib, along with the concurrent use of oral mini-pulse betamethasone, topical minoxidil 5%, and clobetasol lotion. This case highlights the potential efficacy of tofacitinib as a promising therapeutic option for AU, without notable safety concerns. Moreover, it is also well tolerated in this patient. [ABSTRACT FROM AUTHOR]

Published
2023
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