Search

Your search keyword '"Afsar Basha"' showing total 9 results
Start Over Author "Afsar Basha"
9 results on '"Afsar Basha"'

1. An improved class of predictive estimators of population distribution function in the presence of non-response

Author

Mahamood Usman, Garib Nath Singh, Jagadeesh Kumar M S, and Afsar Basha S M

Subjects
Cumulative distribution function, Study variable, Auxiliary variable, Relative efficiency, Absolute bias, Non-response, Science (General), Q1-390, Social sciences (General), H1-99
Abstract

In the present work, we have proposed a novel general class of estimators for the estimation of population distribution function in two distinct situations of non-response. The estimation of distribution function (DF) may play an important role in environmental sciences such as in modelling the annual data of atmospheric NOx temporal concentration, drug removal rates from the body, to present the distribution of gene expression levels across cells etc. Similarly, it may also be useful in other environmental data like groundwater quality, rainfall, wind speed, river discharges, etc. for effective analysis leading to predictive modelling. In this study, it is shown that the suggested estimators of DF are among the best of all other considered estimators. Some estimators are also derived from the proposed family by choosing the suitable values of constants used. Theoretical comparisons of the proposed family of estimators with other family of estimators have been discussed. An empirical study based on two real data sets from literature has been conducted where it has been found that the performance of the proposed family of estimators is superior in terms of enhanced percentage relative efficiencies (PREs) than other family of estimators considered in this study. Further, a simulation study is also carried out which validates the competency behaviour of suggested estimators.

Published
2024
Full Text
View/download PDF

7. Protective Role of Quercetin on Polychlorinated Biphenyls (Aroclor-1254) Induced Oxidative Stress and Apoptosis in Liver of Adult Male Rats

Author

Suganya Sekaran, Balasakthi Janani Madhan Mohan, Selvakumar Kandaswamy, Arunakaran Jagadeesan, Elumalai Perumal, Fariya Yasmine Afsar Basha, and Krishnamoorthy Gunasekaran

Subjects
biology, Health, Toxicology and Mutagenesis, General Medicine, Glutathione, Pharmacology, Toxicology, Aryl hydrocarbon receptor, medicine.disease_cause, Biochemistry, Lipid peroxidation, chemistry.chemical_compound, chemistry, Apoptosis, biology.protein, medicine, Molecular Medicine, Alkaline phosphatase, Quercetin, Molecular Biology, Oxidative stress, Corn oil
Abstract

The present study aims to investigate the protective effect of quercetin against Aroclor-1254–induced hepatotoxicity in rats. Male Wistar rats were grouped into Group I control received vehicle (corn oil; 1 mL/kg bwt); Group II quercetin alone (50 mg/kg bwt/day orally); Group III Aroclor-1254 (2 mg/kg bwt/day intraperitoneally); Group IV Aroclor-1254 + quercetin treated for 30 days. The Aroclor-1254 treatment caused significant alteration in the biochemical parameters (hydrogen peroxide, lipid peroxidation, reduced glutathione levels, and alkaline phosphatase activity). The expressions of apoptotic and antiapoptotic proteins and the liver histology of Aroclor-1254–exposed rats showed cytoplasmic degeneration along with infiltration of polymorphonuclear cells. Whereas simultaneous treatment with quercetin normalized all the biochemical parameters, consequently it inhibited apoptosis mediated by Aroclor-1254 by downregulating aryl hydrocarbon receptor, p53 and apoptotic protein (Bax, caspase-9, caspase-3) and upregulating the antiapoptotic protein (Bcl-2) expression patterns; thereby, quercetin reduces alteration in hepatocellular morphology. Thus quercetin exhibited hepatoprotective effect. © 2012 Wiley Periodicals, Inc. J BiochemMol Toxicol 26:522-532, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/jbt.21466

Published
2012
Full Text
View/download PDF

8. Maternal footprints of Southeast Asians in North India

Author

Kumarasamy Thangaraj, Abhilasha Verma, Chris Tyler-Smith, Sarat Chandra, Thanseem Ismail, Albert Lalremruata, Gyaneshwer Chaubey, Kavita Kumari, Inaganti Amara Jyothi, Deepa Selvi Rani, Niharika Adarsh, Nidhi Shrivastava, Richard Villems, B. Prathap Naidu, Denise Carvalho-Silva, K.R. Bhargavi, Afsar Basha, Amit Kumar Singh, Lalji Singh, Arvind Kumar Gupta, Shailendra Kumar Dhar Dwivedi, Toomas Kivisild, Gurukamal Kaur, Vartika Sonvane, Vijay Kumar Singh, Lakkakula V.K.S. Bhaskar, Alla G. Reddy, Ragala Devasena, Pranav Gupta, Veena Pande, Shefali Singh, Geeta Rao, A. Papa Rao, Chandana Basu Mallick, K. Kondal Reddy, Babita Kumari, and Mait Metspalu

Subjects
Gene Flow, Male, Haplogroup M, Human Y-chromosome DNA haplogroup, Population, India, Mothers, Herpesvirus 1, Human, Biology, DNA, Mitochondrial, Polymorphism, Single Nucleotide, Haplogroup, Asian People, INDEL Mutation, Nepal, Genetics, Ethnicity, Humans, Haplogroup D-M15, education, Genetics (clinical), Asia, Southeastern, Phylogeny, Sequence Deletion, Haplogroup G-M285, education.field_of_study, Original Paper, Base Sequence, Haplotype, Haplogroup L3, eye diseases, Genetics, Population, Haplotypes, Evolutionary biology, RNA, Transfer, Lys, Female
Abstract

We have analyzed 7,137 samples from 125 different caste, tribal and religious groups of India and 99 samples from three populations of Nepal for the length variation in the COII/tRNALys region of mtDNA. Samples showing length variation were subjected to detailed phylogenetic analysis based on HVS-I and informative coding region sequence variation. The overall frequencies of the 9-bp deletion and insertion variants in South Asia were 1.9 and 0.6%, respectively. We have also defined a novel deep-rooting haplogroup M43 and identified the rare haplogroup H14 in Indian populations carrying the 9-bp deletion by complete mtDNA sequencing. Moreover, we redefined haplogroup M6 and dissected it into two well-defined subclades. The presence of haplogroups F1 and B5a in Uttar Pradesh suggests minor maternal contribution from Southeast Asia to Northern India. The occurrence of haplogroup F1 in the Nepalese sample implies that Nepal might have served as a bridge for the flow of eastern lineages to India. The presence of R6 in the Nepalese, on the other hand, suggests that the gene flow between India and Nepal has been reciprocal.

Published
2007

Catalog

Books, media, physical & digital resources
See catalog results