358 results on '"Adibekian, Alexander"'
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2. Programming inactive RNA-binding small molecules into bioactive degraders
3. DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor
4. A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype
5. Chemoproteomic Profiling Maps Zinc-Dependent Cysteine Reactivity
6. Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer
7. Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA
8. Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190
9. Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex
10. Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera
11. Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold–small molecule interactions
12. Altering the Cleaving Effector in Chimeric Molecules that Target RNA Enhances Cellular Selectivity
13. 1-Deoxydihydroceramide causes anoxic death by impairing chaperonin-mediated protein folding
14. Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide.
15. Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera.
16. Correction to “Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA”
17. Chaperone-directed ribosome repair after oxidative damage
18. Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows
19. Serine Hydrolase Activity‐Based Probes for Use in Chemical Proteomics
20. Comprehensive Structure–Activity Relationship Studies of Cepafungin Enabled by Biocatalytic C–H Oxidations
21. Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation
22. DNA-Encoded Library Screening To Inform Design of a Ribonuclease Targeting Chimera (RiboTAC)
23. Comprehensive Structure-Activity Relationship Studies of Cepafungin Enabled by Biocatalytic C–H Oxidations
24. Chaperone-Directed Ribosome Repair after Oxidative Damage
25. Genetic ablation of miR-22 fosters hepatic carcinogenesis in mice
26. Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA
27. Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6
28. Hepatic PTEN Signaling Regulates Systemic Metabolic Homeostasis through Hepatokines-Mediated Liver-to-Peripheral Organs Crosstalk
29. The Pseudo‐Natural Product Rhonin Targets RHOGDI
30. Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening
31. Rational Approach to Identify RNA Targets of Natural Products Enables Identification of Nocathiacin as an Inhibitor of an Oncogenic RNA
32. Dichloro Butenediamides as Irreversible Site-Selective Protein Conjugation Reagent
33. Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway
34. Clinical Antiviral Drug Arbidol Inhibits Infection by SARS-CoV-2 and Variants through Direct Binding to the Spike Protein
35. Dichloro Butenediamides as Irreversible Site‐Selective Protein Conjugation Reagent
36. Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals the DNA Repair Protein XRCC5 as a Functional Target of Myrocin G
37. Recent advances in carbohydrate-based vaccines
38. Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment
39. Chemoenzymatic synthesis of differentially protected 3-deoxysugars
40. Super family-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening
41. Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I
42. Total Synthesis and Target Identification of the Curcusone Diterpenes
43. Genetic Ablation of MiR-22 Fosters Diet-Induced Obesity and NAFLD Development
44. Chemoproteomics‐Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism
45. Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer.
46. Total Synthesis and Chemoproteomics Connect Curcusone Diterpenes with Oncogenic Protein BRAT1
47. Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype
48. Frontispiece: Ethynylation of Cysteine Residues: From Peptides to Proteins in Vitro and in Living Cells
49. Ethynylation of Cysteine Residues: From Peptides to Proteins in Vitro and in Living Cells
50. Targeted Degradation of the Oncogenic MicroRNA 17-92 Cluster by Structure-Targeting Ligands
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