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Bladder cancer, the leading urinary tract cancer, is responsible for 15 deaths daily in the UK. This cancer predominantly manifests as non-muscle-invasive bladder cancer (NMIBC), characterised by tumours not yet penetrating the muscle layer of the bladder wall. NMIBC is plagued by a very high recurrence rate of 70-80% and hence the costliest treatments. Current tools for predicting recurrence use scoring systems that overestimate risk and have poor accuracy. Inaccurate and delayed prediction of recurrence significantly elevates the likelihood of mortality. Accurate prediction of recurrence is hence vital for cost-effective management and treatment planning. This is where Machine learning (ML) techniques have emerged as a promising approach for predicting NMIBC recurrence by leveraging molecular and clinical data. This review provides a comprehensive analysis of ML approaches for predicting NMIBC recurrence. Our systematic evaluation demonstrates the potential of diverse ML algorithms and markers, including radiomic, clinical, histopathological, genomic, and biochemical data in enhancing recurrence prediction and personalised patient management. We summarise various prediction tasks, data modalities, and ML models used, highlighting their performance, limitations, and future directions of incorporating cost-effectiveness. Challenges related to generalisability and interpretability of artificial intelligent models are discussed, emphasising the need for collaborative efforts and robust datasets., Comment: 16 pages, 4 Figures

The physical-layer security (PLS) of wireless networks has witnessed significant attention in next-generation communication systems due to its potential toward enabling protection at the signal level in dense network environments. The growing trends toward smart mobility via sensor-enabled vehicles are transforming today’s traffic environment into Internet of Vehicles (IoVs). Enabling PLS for IoVs would be a significant development considering the dense vehicular network environment in the near future. In this context, this article presents a PLS framework for a vehicular network consisting a legitimate receiver and an eavesdropper, both under the effect of interfering vehicles. The double-Rayleigh fading channel is used to capture the effect of mobility within the communication channel. The performance is analyzed in terms of the average secrecy capacity (ASC) and secrecy outage probability (SOP). We present the standard expressions for the ASC and SOP in alternative forms, to facilitate analysis in terms of the respective moment generating function (MGF) and characteristic function of the joint fading and interferer statistics. Closed-form expressions for the MGFs and characteristic functions were obtained and Monte Carlo simulations were provided to validate the results. Approximate expressions for the ASC and SOP were also provided, for easier analysis and insight into the effect of the network parameters. The results attest that the performance of the considered system was affected by the number of interfering vehicles as well as their distances. It was also demonstrated that the system performance closely correlates with the uncertainty in the eavesdropper’s vehicle location.

The physical-layer security (PLS) of wireless networks has witnessed significant attention in next-generation communication systems due to its potential toward enabling protection at the signal level in dense network environments. The growing trends toward smart mobility via sensor-enabled vehicles are transforming today’s traffic environment into Internet of Vehicles (IoVs). Enabling PLS for IoVs would be a significant development considering the dense vehicular network environment in the near future. In this context, this article presents a PLS framework for a vehicular network consisting a legitimate receiver and an eavesdropper, both under the effect of interfering vehicles. The double-Rayleigh fading channel is used to capture the effect of mobility within the communication channel. The performance is analyzed in terms of the average secrecy capacity (ASC) and secrecy outage probability (SOP). We present the standard expressions for the ASC and SOP in alternative forms, to facilitate analysis in terms of the respective moment generating function (MGF) and characteristic function of the joint fading and interferer statistics. Closed-form expressions for the MGFs and characteristic functions were obtained and Monte Carlo simulations were provided to validate the results. Approximate expressions for the ASC and SOP were also provided, for easier analysis and insight into the effect of the network parameters. The results attest that the performance of the considered system was affected by the number of interfering vehicles as well as their distances. It was also demonstrated that the system performance closely correlates with the uncertainty in the eavesdropper’s vehicle location.

Underwater Sensor Networks (UWSNs) has witnessed significant R&D attention in both academia and industries due to its growing application domain such as border security, freight via sea or river, natural petroleum production, etc. Considering the deep underwater oriented access constraints, energy centric communication for lifetime maximization of tiny sensor nodes in UWSNs is one of the key research themes in this domain. Existing literature on green UWSNs are majorly adapted from the existing techniques in traditional wireless sensor network without giving much attention to the realistic impact of underwater network environments resulting in degraded performance. Towards this end, this paper presents an adapted whale optimization algorithm-based energy and delay centric green UWSNs framework (W-GUN). It focuses on exploiting dynamic underwater network characteristics by effectively utilizing underwater whale centric optimization in relay node selection. Firstly, an underwater relay- node optimization model is mathematically derived focusing on whale and wolf optimization algorithms for incorporating realistic underwater characteristics. Secondly, the optimization model is used to develop an adapted whale and grey wolf optimization algorithm. Thirdly, a complete work-flow of the W-GUN framework is presented with the optimization flowchart. The comparative performance evaluation attests the benefits of the proposed framework as compared to the state-of-the-art techniques considering various metrics related to underwater network environments.

Minimizing energy consumption is one of the major challenges in wireless sensor networks (WSNs) due to the limited size of batteries and the resource constrained tiny sensor nodes. Energy harvesting in wireless sensor networks (EH-WSNs) is one of the promising solutions to minimize the energy consumption in wireless sensor networks for prolonging the overall network lifetime. However, static energy harvesting in individual sensor nodes is normally limited and unbalanced among the network nodes. In this context, this paper proposes a modified echo state network (MESN) based dynamic duty cycle with optimal opportunistic routing (OOR) for EH-WSNs. The proposed model is used to act as a predictor for finding the expected energy consumption of the next slot in dynamic duty cycle. The model has adapted a whale optimization algorithm (WOA) for optimally selecting the weights of the neurons in the reservoir layer of the echo state network towards minimizing energy consumption at each node as well as at the network level. The adapted WOA enabled energy harvesting model provides stable output from the MESN relying on optimal weight selection in the reservoir layer. The dynamic duty cycle is updated based on energy consumption and optimal threshold energy for transmission and reception at bit level. The proposed OOR scheme uses multiple energy centric parameters for selecting the relay set oriented forwarding paths for each neighbor nodes. The performance analysis of the proposed model in realistic environments attests the benefits in terms of energy centric metrics such as energy consumption, network lifetime, delay, packet delivery ratio and throughput as compared to the state-of-the-art-techniques.