1. Less sedentary time is associated with a more favourable glucose-insulin axis in obese pregnant women—a secondary analysis of the DALI study
- Author
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Dieberger, A.M. (Anna M.), Desoye, G. (Gernot), Stolz, E. (Erwin), Hill, D.J. (David), Corcoy, R. (Rosa), Simmons, D. (David), Harreiter, J. (Jurgen), Kautzky-Willer, A. (Alexandra), Dunne, F. (Fidelma), Devlieger, R. (Roland), Wender-Ozegowska, E. (Ewa), Zawiejska, A. (Agnieszka), Lapolla, A. (Annunziata), Dalfra, M.G. (Maria G.), Bertolotto, A. (Alessandra), Galjaard, S. (Sander), Adelantado, J.M. (Juan M), Jensen, D.M. (Dorte M.), Andersen, L.-L. (Lise-Lotte), Tanvig, M. (Mette), Damm, P. (Peter), Mathiesen, E. (E.), Snoek, F.J. (Frank), Jelsma, J.G.M. (Judith G. M.), Poppel, M.N. (Mireille) van, Dieberger, A.M. (Anna M.), Desoye, G. (Gernot), Stolz, E. (Erwin), Hill, D.J. (David), Corcoy, R. (Rosa), Simmons, D. (David), Harreiter, J. (Jurgen), Kautzky-Willer, A. (Alexandra), Dunne, F. (Fidelma), Devlieger, R. (Roland), Wender-Ozegowska, E. (Ewa), Zawiejska, A. (Agnieszka), Lapolla, A. (Annunziata), Dalfra, M.G. (Maria G.), Bertolotto, A. (Alessandra), Galjaard, S. (Sander), Adelantado, J.M. (Juan M), Jensen, D.M. (Dorte M.), Andersen, L.-L. (Lise-Lotte), Tanvig, M. (Mette), Damm, P. (Peter), Mathiesen, E. (E.), Snoek, F.J. (Frank), Jelsma, J.G.M. (Judith G. M.), and Poppel, M.N. (Mireille) van
- Abstract
Background/objectives: Obese pregnant women are at high risk of developing gestational diabetes mellitus (GDM), which might be reduced by sufficient physical activity (PA) and reduced sedentary time (ST). We assessed whether PA and ST are longitudinally associated with the glucose-insulin axis in obese pregnant women. Subjects/methods: In this secondary analysis of the DALI (vitamin D And Lifestyle Intervention for gestational diabetes mellitus prevention) study, pregnant women, <20 weeks gestation, with a pre-pregnancy body mass index (BMI) ≥ 29 kg/m2, without GDM on entry were included. Time spent in moderate-to-vigorous PA (MVPA) and ST were measured objectively with accelerometers at <20 weeks, 24–28 weeks and 35–37 weeks of gestation. Fasting glucose (mmol/l) and insulin (mU/l), insulin resistance (HOMA-IR) and first-phase and second-phase insulin release (Stumvoll first and second phase) were assessed at the same time. Linear mixed regression models were used to calculate between-participant differences and within-participant changes over time. Analyses were adjusted for gestational age, randomisation, pre-pregnancy BMI, education and age. MVPA, I
- Published
- 2020
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