Search

Your search keyword '"Addamo, A"' showing total 1,108 results
Start Over Author "Addamo, A"

Refine your results

more »

more »

more »

more »
1,108 results on '"Addamo, A"'

4. Feasibility Study on Additive Manufacturing of Feed Horn Operating in D-Band

Author

Giuseppe Addamo, Lorenzo Scalcinati, Mario Zannoni, Oscar Antonio Peverini, and Flaviana Calignano

Subjects
PBF-LB/M, additive manufacturing, smooth wall horn, D-band, Chemical technology, TP1-1185
Abstract

This paper presents the outcomes of a feasibility study on the manufacturing of D-band horn antennas through the Low Power Bed Fusion process. Different prototypes have been realized and tested, showing nice results in terms of the co-polarization component. On the other hand, a spurious cross-polarization component is present in the radiation pattern even in the principal planes, limiting the device to single-polarization applications. A mechanical study of the realized devices has been conducted on the horn internal channel to understand the reasons for this issue, and, subsequently, to address where to improve the manufacturing process.

Published
2025
Full Text
View/download PDF

6. The LSPE-Strip beams

Author

Realini, S., Franceschet, C., Villa, F., Sandri, M., Addamo, G., Alonso-Arias, P., Bersanelli, M., Cuttaia, F., Jones, M., Maris, M., Mena, F. P., Mennella, A., Molina, R., Morgante, G., Tomasi, M., and Zannoni, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

In this paper we describe the design and characterization of the optical system of LSPE/Strip, a coherent polarimeter array that will observe the microwave sky from the Teide Observatory in Tenerife in two frequency bands centred at 43 and 95 GHz through a dual-reflector crossed-Dragone telescope of 1.5 m aperture. In general, optical systems composed by a telescopefeed array assembly have non-idealities that might limit their ability to perform high-precision measurements. It is thus necessary to understand, characterize and properly control these systematic effects. For this reason, we performed electromagnetic simulations to characterize angular resolution, sidelobes, main beam symmetry, polarization purity and feedhorns orientation. The results presented in this paper will be an essential input for further optical studies and for the LSPE/Strip data analysis. Ultimately, they will be used to assess the impact of optical systematic effects on the scientific results., Comment: 18 pages, 13 figures

Published
2021
Full Text
View/download PDF

7. The LSPE-Strip feed horn array

Author

Franceschet, C., Del Torto, F., Villa, F., Realini, S., Bongiolatti, R., Peverini, O. A., Pezzotta, F., Viganó, D. M., Addamo, G., Bersanelli, M., Cavaliere, F., Cuttaia, F., Gervasi, M., Mennella, A., Morgante, G., Taylor, A. C., Virone, G., and Zannoni, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

In this paper we discuss the design, manufacturing and characterization of the feed horn array of the Strip instrument of the Large Scale Polarization Explorer (LSPE) experiment. Strip is a microwave telescope, operating in the Q- and W-band, for the observation of the polarized emissions from the sky in a large fraction (about 37%) of the Northern hemisphere with subdegree angular resolution. The Strip focal plane is populated by forty-nine Q-band and six W-band corrugated horns, each feeding a cryogenically cooled polarimeter for the detection of the Stokes $Q$ and $U$ components of the polarized signal from the sky. The Q-band channel is designed to accurately monitor Galactic polarized synchrotron emission, while the combination of Q- and W-band will allow the study of atmospheric effects at the observation site, the Observatorio del Teide, in Tenerife. In this paper we focus on the development of the Strip corrugated feed horns, including design requirements, engineering and manufacturing, as well as detailed characterization and performance verification., Comment: Version 1: This paper (28 pages, 25 figures) is part of the Special Issue "The LSPE/Strip instrument description and testing", being submitted to JINST. Version 2: Added new references. Splitting of design and specifications tables in Sec. 2.1. Other minor revisions included

Published
2021
Full Text
View/download PDF

8. Ridged Apertures for LEO Direct Radiating Arrays in Ka-Band

Author

Carlos Vazquez-Sogorb, Roger Montoya-Roca, Giuseppe Addamo, Oscar Antonio Peverini, and Giuseppe Virone

Subjects
open-ended waveguide, direct radiating array, LEO satellite, satellite communication, non-terrestrial networks, Ka-band, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999
Abstract

This paper presents an extensive performance analysis of open-ended waveguide elements for direct radiating arrays with a high scan angle (±50° /60°). The evaluated designs are based on square and hexagonal apertures loaded with ridges. Both square and triangular lattices are considered in the framework of Ka-band downlink design requirements for future LEO mega-constellations. The parameter space defined by the monomodal condition has been explored to find an optimum value for each structure. The analyses carried out with both infinite and finite full-wave models in terms of active reflection coefficient, scan loss and cross-polar discrimination are in good agreement.

Published
2024
Full Text
View/download PDF

9. The large scale polarization explorer (LSPE) for CMB measurements: performance forecast

Author

The LSPE collaboration, Addamo, G., Ade, P. A. R., Baccigalupi, C., Baldini, A. M., Battaglia, P. M., Battistelli, E. S., Baù, A., de Bernardis, P., Bersanelli, M., Biasotti, M., Boscaleri, A., Caccianiga, B., Caprioli, S., Cavaliere, F., Cei, F., Cleary, K. A., Columbro, F., Coppi, G., Coppolecchia, A., Cuttaia, F., D'Alessandro, G., De Gasperis, G., De Petris, M., Fafone, V., Farsian, F., Barusso, L. Ferrari, Fontanelli, F., Franceschet, C., Gaier, T. C., Galli, L., Gatti, F., Genova-Santos, R., Gerbino, M., Gervasi, M., Ghigna, T., Grosso, D., Gruppuso, A., Gualtieri, R., Incardona, F., Jones, M. E., Kangaslahti, P., Krachmalnicoff, N., Lamagna, L., Lattanzi, M., López-Caraballo, C. H., Lumia, M., Mainini, R., Maino, D., Mandelli, S., Maris, M., Masi, S., Matarrese, S., May, A., Mele, L., Mena, P., Mennella, A., Molina, R., Molinari, D., Morgante, G., Natale, U., Nati, F., Natoli, P., Pagano, L., Paiella, A., Panico, F., Paonessa, F., Paradiso, S., Passerini, A., Perez-de-Taoro, M., Peverini, O. A., Piacentini, F., Piccirillo, L., Pisano, G., Poletti, D., Presta, G., Realini, S., Reyes, N., Rubino-Martin, J. A., Sandri, M., Sartor, S., Pezzotta, F., Polenta, G., Rocchi, A., Schillaci, A., Signorelli, G., Siri, B., Soria, M., Spinella, F., Tapia, V., Tartari, A., Taylor, A. C., Terenzi, L., Tomasi, M., Tommasi, E., Tucker, C., Vaccaro, D., Vigano, D. M., Villa, F., Virone, G., Vittorio, N., Volpe, A., Watkins, R. E. J., Zacchei, A., and Zannoni, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

[Abridged] The measurement of the polarization of the Cosmic Microwave Background radiation is one of the current frontiers in cosmology. In particular, the detection of the primordial B-modes, could reveal the presence of gravitational waves in the early Universe. The detection of such component is at the moment the most promising technique to probe the inflationary theory describing the very early evolution of the Universe. We present the updated performance forecast of the Large Scale Polarization Explorer (LSPE), a program dedicated to the measurement of the CMB polarization. LSPE is composed of two instruments: Strip, a radiometer-based telescope on the ground in Tenerife, and SWIPE (Short-Wavelength Instrument for the Polarization Explorer) a bolometer-based instrument designed to fly on a winter arctic stratospheric long-duration balloon. The program is among the few dedicated to observation of the Northern Hemisphere, while most of the international effort is focused into ground-based observation in the Southern Hemisphere. Measurements are currently scheduled in Winter 2021/22 for SWIPE, with a flight duration up to 15 days, and in Summer 2021 with two years observations for Strip. We describe the main features of the two instruments, identifying the most critical aspects of the design, in terms of impact into performance forecast. We estimate the expected sensitivity of each instrument and propagate their combined observing power to the sensitivity to cosmological parameters, including the effect of scanning strategy, component separation, residual foregrounds and partial sky coverage. We also set requirements on the control of the most critical systematic effects and describe techniques to mitigate their impact. LSPE can reach a sensitivity in tensor-to-scalar ratio of $\sigma_r<0.01$, and improve constrains on other cosmological parameters., Comment: Submitted to JCAP. Abstract abridged for arXiv submission

Published
2020
Full Text
View/download PDF

10. Progress report on the Large Scale Polarization Explorer

Author

Lamagna, L., Addamo, G., Ade, P. A. R., Baccigalupi, C., Baldini, A. M., Battaglia, P. M., Battistelli, E., Baù, A., Bersanelli, M., Biasotti, M., Boragno, C., Boscaleri, A., Caccianiga, B., Caprioli, S., Cavaliere, F., Cei, F., Cleary, K. A., Columbro, F., Coppi, G., Coppolecchia, A., Corsini, D., Cuttaia, F., D'Alessandro, G., de Bernardis, P., De Gasperis, G., De Petris, M., Del Torto, F., Fafone, V., Farooqui, Z., Farsian, F., Fontanelli, F., Franceschet, C., Gaier, T. C., Gatti, F., Genova-Santos, R., Gervasi, M., Ghigna, T., Grassi, M., Grosso, D., Gualtieri, R., Incardona, F., Jones, M., Kangaslahti, P., Krachmalnicoff, N., Mainini, R., Maino, D., Mandelli, S., Maris, M., Masi, S., Matarrese, S., May, A., Mena, P., Mennella, A., Molina, R., Molinari, D., Morgante, G., Nati, F., Natoli, P., Pagano, L., Paiella, A., Paonessa, F., Passerini, A., Perez-de-Taoro, M., Peverini, O. A., Pezzotta, F., Piacentini, F., Piccirillo, L., Pisano, G., Polastri, L., Polenta, G., Poletti, D., Presta, G., Realini, S., Reyes, N., Rocchi, A., Rubiño-Martin, J. A., Sandri, M., Sartor, S., Schillaci, A., Signorelli, G., Siri, B., Soria, M., Spinella, F., Tapia, V., Tartari, A., Taylor, A., Terenzi, L., Tomasi, M., Tommasi, E., Tucker, C., Vaccaro, D., Vigano, D. M., Villa, F., Virone, G., Vittorio, N., Volpe, A., Watkins, B., Zacchei, A., and Zannoni, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The Large Scale Polarization Explorer (LSPE) is a cosmology program for the measurement of large scale curl-like features (B-modes) in the polarization of the Cosmic Microwave Background. Its goal is to constrain the background of inflationary gravity waves traveling through the universe at the time of matter-radiation decoupling. The two instruments of LSPE are meant to synergically operate by covering a large portion of the northern microwave sky. LSPE/STRIP is a coherent array of receivers planned to be operated from the Teide Observatory in Tenerife, for the control and characterization of the low-frequency polarized signals of galactic origin; LSPE/SWIPE is a balloon-borne bolometric polarimeter based on 330 large throughput multi-moded detectors, designed to measure the CMB polarization at 150 GHz and to monitor the polarized emission by galactic dust above 200 GHz. The combined performance and the expected level of systematics mitigation will allow LSPE to constrain primordial B-modes down to a tensor/scalar ratio of $10^{-2}$. We here report the status of the STRIP pre-commissioning phase and the progress in the characterization of the key subsystems of the SWIPE payload (namely the cryogenic polarization modulation unit and the multi-moded TES pixels) prior to receiver integration., Comment: 8 pages, 5 figures, Accepted for publication in Journal of Low Temperature Physics

Published
2020
Full Text
View/download PDF

11. How 3D-Printing Is Changing RF Front-End Design for Space Applications

Author

Oscar A. Peverini, Mauro Lumia, Giuseppe Addamo, Giuseppe Virone, and Nelson J. G. Fonseca

Subjects
MTT 70th Anniversary Special Issue, 3D-printing, additive manufacturing, microwave components, multiple beam antennas, array antennas, Telecommunication, TK5101-6720, Electric apparatus and materials. Electric circuits. Electric networks, TK452-454.4
Abstract

3D-printing is leading to a major transformation in many industrial and application sectors, ranging from medical to aerospace. In the space sector, 3D-printing has firstly been adopted for the development of structural and thermal parts, such as brackets and heat pipes. In more recent years, thanks to improvements in precision and surface roughness, 3D-printing technologies have steadily been investigated also for the development of radio frequency components and advanced payloads. Indeed, the unique features of 3D-printing, including the free-form capability and the ease for customization, make these manufacturing technologies very appealing in the development of complex radio-frequency front-ends for space applications, including New Space constellations and next generation software-defined communication satellites. They also enable a drastic simplification of mechanical designs by reducing the number of interfaces and assembling screws of large radio-frequency front-ends, thus leading to significant mass savings and higher integration. This paper briefly reports on recent advances in 3D-printing that have been carried out according to the current trends in radio-frequency front-ends for satellite communications.

Published
2023
Full Text
View/download PDF

12. The STRIP instrument of the Large Scale Polarization Explorer: microwave eyes to map the Galactic polarized foregrounds

Author

Franceschet, C., Realini, S., Mennella, A., Addamo, G., Baù, A., Battaglia, P. M., Bersanelli, M., Caccianiga, B., Caprioli, S., Cavaliere, F., Cleary, K. A., Cuttaia, F., Del Torto, F., Fafone, V., Farooqui, Z., Santos, R. T. Génova, Gaier, T. C., Gervasi, M., Ghigna, T., Incardona, F., Iovenitti, S., Jones, M., Kangaslahti, P., Mainini, R., Maino, D., Maris, M., Mena, P., Molina, R., Morgante, G., Passerini, A., Perez-de-Taoro, M., Peverini, O. A., Pezzotta, F., Pincella, C., Reyes, N., Rocchi, A., Rubiño-Martín, J. A., Sandri, M., Sartor, S., Soria, M., Tapia, V., Terenzi, L., Tomasi, M., Tommasi, E., Viganó, D. M., Villa, F., Virone, G., Volpe, A., Watkins, B., Zacchei, A., and Zannoni, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

In this paper we discuss the latest developments of the STRIP instrument of the "Large Scale Polarization Explorer" (LSPE) experiment. LSPE is a novel project that combines ground-based (STRIP) and balloon-borne (SWIPE) polarization measurements of the microwave sky on large angular scales to attempt a detection of the "B-modes" of the Cosmic Microwave Background polarization. STRIP will observe approximately 25% of the Northern sky from the "Observatorio del Teide" in Tenerife, using an array of forty-nine coherent polarimeters at 43 GHz, coupled to a 1.5 m fully rotating crossed-Dragone telescope. A second frequency channel with six-elements at 95 GHz will be exploited as an atmospheric monitor. At present, most of the hardware of the STRIP instrument has been developed and tested at sub-system level. System-level characterization, starting in July 2018, will lead STRIP to be shipped and installed at the observation site within the end of the year. The on-site verification and calibration of the whole instrument will prepare STRIP for a 2-years campaign for the observation of the CMB polarization., Comment: 17 pages, 15 figures, proceedings of the SPIE Astronomical Telescopes + Instrumentation conference "Millimeter, Submillimeter, and Far-Infrared Detectors and Instrumentation for Astronomy IX", on June 15th, 2018, Austin (TX)

Published
2018
Full Text
View/download PDF

13. The shrunk genetic diversity of coral populations in North-Central Patagonia calls for management and conservation plans for marine resources

Author

Anna Maria Addamo, Serena Zaccara, Vreni Häussermann, Juan Höfer, Günter Försterra, Ricardo García-Jiménez, Giuseppe Crosa, and Annie Machordom

Subjects
Medicine, Science
Abstract

Abstract The Chilean Patagonia is a complex puzzle of numerous fjords, channels, bays, estuaries, and islands. The largest part of it is very remote, hampering the generation of scientific knowledge and effective management planning that could balance conservation of the marine resources with the increasing development of aquaculture activities. The present study focuses on the deep-water emergent cold-water coral Desmophyllum dianthus, dwelling in Chilean Patagonia, with the aim to illustrate its population genetic structure, demography and adaptation of the species along this coast. Microsatellite loci analysis included D. dianthus individuals from twelve sampling localities along bathymetric and oceanographic gradients from the latitude 40°S to 48°S. The results showed a lack of genetic structure with an asymmetric dispersion of individuals, and relevant heterozygosity deficiency in some populations. This study also analyses the natural and human impacts affecting the region (e.g., climate change, increasing salmon farming activities), and stresses the importance of including genetic information in the process of management and conservation of marine resources. In particular, the relevance of using interdisciplinary approaches to fill the gaps in scientific knowledge especially in remote and pristine areas of western Patagonia. Therefore, information on genetic spatial distribution of marine fauna could become pivotal to develop a holistic ecosystem-based approach for marine spatial planning.

Published
2022
Full Text
View/download PDF

15. Feasibility Study on Additive Manufacturing of Feed Horn Operating in D-Band.

Author

Addamo, Giuseppe, Scalcinati, Lorenzo, Zannoni, Mario, Peverini, Oscar Antonio, and Calignano, Flaviana

Subjects
HORN antennas, MANUFACTURING processes, FEED additives, FEASIBILITY studies, PROTOTYPES
Abstract

This paper presents the outcomes of a feasibility study on the manufacturing of D-band horn antennas through the Low Power Bed Fusion process. Different prototypes have been realized and tested, showing nice results in terms of the co-polarization component. On the other hand, a spurious cross-polarization component is present in the radiation pattern even in the principal planes, limiting the device to single-polarization applications. A mechanical study of the realized devices has been conducted on the horn internal channel to understand the reasons for this issue, and, subsequently, to address where to improve the manufacturing process. [ABSTRACT FROM AUTHOR]

Published
2025
Full Text
View/download PDF

20. Large Horizontal Near-Field Scanner Based on a Non-Tethered Unmanned Aerial Vehicle

Author

Lorenzo Ciorba, Giuseppe Virone, Fabio Paonessa, Marco Righero, Eloy De Lera Acedo, Stefania Matteoli, Edgar Colin Beltran, Pietro Bolli, Giorgio Giordanengo, Giuseppe Vecchi, Alessio Magro, Riccardo Chiello, Oscar A. Peverini, and Giuseppe Addamo

Subjects
Antenna measurements, near-field measurements, unmanned aerial vehicle, digital beamforming array, phased-array radio telescopes, array calibration, Telecommunication, TK5101-6720
Abstract

A horizontal planar scanner with an approximate size of 40 m $\times40$ m has been implemented using the Unmanned Aerial Vehicle (UAV) technology. The UAV is not wired to the ground to maintain the flexibility and short setup time of a non-tethered flight. In this configuration, the UAV-mounted continuous-wave source is not phase-locked to the on-the-ground receiver. A dual-polarized reference antenna placed on the ground is hence used to retrieve the relevant phase information. The presented approach has been applied on the Pre - Aperture Array Verification System (Pre -AAVS1) of the Square Kilometre Array, which is a digital beamformed array with 16 active elements. An inverse source technique has been applied on measured Near-Field (NF) data acquired on two different sets of points (one for each electric field component) from all the receiver channels. In this way, Embedded Element Patterns (EEPs), array calibration coefficients and pattern have been determined from NF data only. The achieved results have been validated using a complementary set of Far-Field (FF) measurements and simulations.

Published
2022
Full Text
View/download PDF

24. Ridged Apertures for LEO Direct Radiating Arrays in Ka-Band.

Author

Vazquez-Sogorb, Carlos, Montoya-Roca, Roger, Addamo, Giuseppe, Peverini, Oscar Antonio, and Virone, Giuseppe

Subjects
PHASED array antennas, TELECOMMUNICATION satellites, REFLECTANCE, ANGLES
Abstract

This paper presents an extensive performance analysis of open-ended waveguide elements for direct radiating arrays with a high scan angle (±50° /60°). The evaluated designs are based on square and hexagonal apertures loaded with ridges. Both square and triangular lattices are considered in the framework of Ka-band downlink design requirements for future LEO mega-constellations. The parameter space defined by the monomodal condition has been explored to find an optimum value for each structure. The analyses carried out with both infinite and finite full-wave models in terms of active reflection coefficient, scan loss and cross-polar discrimination are in good agreement. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

29. Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for Psychosis

Author

Wannan, Cassandra M J, primary, Nelson, Barnaby, additional, Addington, Jean, additional, Allott, Kelly, additional, Anticevic, Alan, additional, Arango, Celso, additional, Baker, Justin T, additional, Bearden, Carrie E, additional, Billah, Tashrif, additional, Bouix, Sylvain, additional, Broome, Matthew R, additional, Buccilli, Kate, additional, Cadenhead, Kristin S, additional, Calkins, Monica E, additional, Cannon, Tyrone D, additional, Cecci, Guillermo, additional, Chen, Eric Yu Hai, additional, Cho, Kang Ik K, additional, Choi, Jimmy, additional, Clark, Scott R, additional, Coleman, Michael J, additional, Conus, Philippe, additional, Corcoran, Cheryl M, additional, Cornblatt, Barbara A, additional, Diaz-Caneja, Covadonga M, additional, Dwyer, Dominic, additional, Ebdrup, Bjørn H, additional, Ellman, Lauren M, additional, Fusar-Poli, Paolo, additional, Galindo, Liliana, additional, Gaspar, Pablo A, additional, Gerber, Carla, additional, Glenthøj, Louise Birkedal, additional, Glynn, Robert, additional, Harms, Michael P, additional, Horton, Leslie E, additional, Kahn, René S, additional, Kambeitz, Joseph, additional, Kambeitz-Ilankovic, Lana, additional, Kane, John M, additional, Kapur, Tina, additional, Keshavan, Matcheri S, additional, Kim, Sung-Wan, additional, Koutsouleris, Nikolaos, additional, Kubicki, Marek, additional, Kwon, Jun Soo, additional, Langbein, Kerstin, additional, Lewandowski, Kathryn E, additional, Light, Gregory A, additional, Mamah, Daniel, additional, Marcy, Patricia J, additional, Mathalon, Daniel H, additional, McGorry, Patrick D, additional, Mittal, Vijay A, additional, Nordentoft, Merete, additional, Nunez, Angela, additional, Pasternak, Ofer, additional, Pearlson, Godfrey D, additional, Perez, Jesus, additional, Perkins, Diana O, additional, Powers, Albert R, additional, Roalf, David R, additional, Sabb, Fred W, additional, Schiffman, Jason, additional, Shah, Jai L, additional, Smesny, Stefan, additional, Spark, Jessica, additional, Stone, William S, additional, Strauss, Gregory P, additional, Tamayo, Zailyn, additional, Torous, John, additional, Upthegrove, Rachel, additional, Vangel, Mark, additional, Verma, Swapna, additional, Wang, Jijun, additional, Rossum, Inge Winter-van, additional, Wolf, Daniel H, additional, Wolff, Phillip, additional, Wood, Stephen J, additional, Yung, Alison R, additional, Agurto, Carla, additional, Alvarez-Jimenez, Mario, additional, Amminger, Paul, additional, Armando, Marco, additional, Asgari-Targhi, Ameneh, additional, Cahill, John, additional, Carrión, Ricardo E, additional, Castro, Eduardo, additional, Cetin-Karayumak, Suheyla, additional, Mallar Chakravarty, M, additional, Cho, Youngsun T, additional, Cotter, David, additional, D’Alfonso, Simon, additional, Ennis, Michaela, additional, Fadnavis, Shreyas, additional, Fonteneau, Clara, additional, Gao, Caroline, additional, Gupta, Tina, additional, Gur, Raquel E, additional, Gur, Ruben C, additional, Hamilton, Holly K, additional, Hoftman, Gil D, additional, Jacobs, Grace R, additional, Jarcho, Johanna, additional, Ji, Jie Lisa, additional, Kohler, Christian G, additional, Lalousis, Paris Alexandros, additional, Lavoie, Suzie, additional, Lepage, Martin, additional, Liebenthal, Einat, additional, Mervis, Josh, additional, Murty, Vishnu, additional, Nicholas, Spero C, additional, Ning, Lipeng, additional, Penzel, Nora, additional, Poldrack, Russell, additional, Polosecki, Pablo, additional, Pratt, Danielle N, additional, Rabin, Rachel, additional, Rahimi Eichi, Habiballah, additional, Rathi, Yogesh, additional, Reichenberg, Avraham, additional, Reinen, Jenna, additional, Rogers, Jack, additional, Ruiz-Yu, Bernalyn, additional, Scott, Isabelle, additional, Seitz-Holland, Johanna, additional, Srihari, Vinod H, additional, Srivastava, Agrima, additional, Thompson, Andrew, additional, Turetsky, Bruce I, additional, Walsh, Barbara C, additional, Whitford, Thomas, additional, Wigman, Johanna T W, additional, Yao, Beier, additional, Yuen, Hok Pan, additional, Ahmed, Uzair, additional, Byun, Andrew (Jin Soo), additional, Chung, Yoonho, additional, Do, Kim, additional, Hendricks, Larry, additional, Huynh, Kevin, additional, Jeffries, Clark, additional, Lane, Erlend, additional, Langholm, Carsten, additional, Lin, Eric, additional, Mantua, Valentina, additional, Santorelli, Gennarina, additional, Ruparel, Kosha, additional, Zoupou, Eirini, additional, Adasme, Tatiana, additional, Addamo, Lauren, additional, Adery, Laura, additional, Ali, Munaza, additional, Auther, Andrea, additional, Aversa, Samantha, additional, Baek, Seon-Hwa, additional, Bates, Kelly, additional, Bathery, Alyssa, additional, Bayer, Johanna M M, additional, Beedham, Rebecca, additional, Bilgrami, Zarina, additional, Birch, Sonia, additional, Bonoldi, Ilaria, additional, Borders, Owen, additional, Borgatti, Renato, additional, Brown, Lisa, additional, Bruna, Alejandro, additional, Carrington, Holly, additional, Castillo-Passi, Rolando I, additional, Chen, Justine, additional, Cheng, Nicholas, additional, Ching, Ann Ee, additional, Clifford, Chloe, additional, Colton, Beau-Luke, additional, Contreras, Pamela, additional, Corral, Sebastián, additional, Damiani, Stefano, additional, Done, Monica, additional, Estradé, Andrés, additional, Etuka, Brandon Asika, additional, Formica, Melanie, additional, Furlan, Rachel, additional, Geljic, Mia, additional, Germano, Carmela, additional, Getachew, Ruth, additional, Goncalves, Mathias, additional, Haidar, Anastasia, additional, Hartmann, Jessica, additional, Jo, Anna, additional, John, Omar, additional, Kerins, Sarah, additional, Kerr, Melissa, additional, Kesselring, Irena, additional, Kim, Honey, additional, Kim, Nicholas, additional, Kinney, Kyle, additional, Krcmar, Marija, additional, Kotler, Elana, additional, Lafanechere, Melanie, additional, Lee, Clarice, additional, Llerena, Joshua, additional, Markiewicz, Christopher, additional, Matnejl, Priya, additional, Maturana, Alejandro, additional, Mavambu, Aissata, additional, Mayol-Troncoso, Rocío, additional, McDonnell, Amelia, additional, McGowan, Alessia, additional, McLaughlin, Danielle, additional, McIlhenny, Rebecca, additional, McQueen, Brittany, additional, Mebrahtu, Yohannes, additional, Mensi, Martina, additional, Hui, Christy Lai Ming, additional, Suen, Yi Nam, additional, Wong, Stephanie Ming Yin, additional, Morrell, Neal, additional, Omar, Mariam, additional, Partridge, Alice, additional, Phassouliotis, Christina, additional, Pichiecchio, Anna, additional, Politi, Pierluigi, additional, Porter, Christian, additional, Provenzani, Umberto, additional, Prunier, Nicholas, additional, Raj, Jasmine, additional, Ray, Susan, additional, Rayner, Victoria, additional, Reyes, Manuel, additional, Reynolds, Kate, additional, Rush, Sage, additional, Salinas, Cesar, additional, Shetty, Jashmina, additional, Snowball, Callum, additional, Tod, Sophie, additional, Turra-Fariña, Gabriel, additional, Valle, Daniela, additional, Veale, Simone, additional, Whitson, Sarah, additional, Wickham, Alana, additional, Youn, Sarah, additional, Zamorano, Francisco, additional, Zavaglia, Elissa, additional, Zinberg, Jamie, additional, Woods, Scott W, additional, and Shenton, Martha E, additional

Published
2024
Full Text
View/download PDF

30. Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for Psychosis

Author

Wannan, CMJ, Nelson, B, Addington, J, Allott, K, Anticevic, A, Arango, C, Baker, JT, Bearden, CE, Billah, T, Bouix, S, Broome, MR, Buccilli, K, Cadenhead, KS, Calkins, ME, Cannon, TD, Cecci, G, Chen, EYH, Cho, KIK, Choi, J, Clark, SR, Coleman, MJ, Conus, P, Corcoran, CM, Cornblatt, BA, Diaz-Caneja, CM, Dwyer, D, Ebdrup, BH, Ellman, LM, Fusar-Poli, P, Galindo, L, Gaspar, PA, Gerber, C, Glenthoj, LB, Glynn, R, Harms, MP, Horton, LE, Kahn, RS, Kambeitz, J, Kambeitz-Ilankovic, L, Kane, JM, Kapur, T, Keshavan, MS, Kim, S-W, Koutsouleris, N, Kubicki, M, Kwon, JS, Langbein, K, Lewandowski, KE, Light, GA, Mamah, D, Marcy, PJ, Mathalon, DH, McGorry, PD, Mittal, VA, Nordentoft, M, Nunez, A, Pasternak, O, Pearlson, GD, Perez, J, Perkins, DO, Powers, AR, Roalf, DR, Sabb, FW, Schiffman, J, Shah, JL, Smesny, S, Spark, J, Stone, WS, Strauss, GP, Tamayo, Z, Torous, J, Upthegrove, R, Vangel, M, Verma, S, Wang, J, Winter-van Rossum, I, Wolf, DH, Wolff, P, Wood, SJ, Yung, AR, Agurto, C, Alvarez-Jimenez, M, Amminger, P, Armando, M, Asgari-Targhi, A, Cahill, J, Carrion, RE, Castro, E, Cetin-Karayumak, S, Chakravarty, MM, Cho, YT, Cotter, D, D'Alfonso, S, Ennis, M, Fadnavis, S, Fonteneau, C, Gao, C, Gupta, T, Gur, RE, Gur, RC, Hamilton, HK, Hoftman, GD, Jacobs, GR, Jarcho, J, Ji, JL, Kohler, CG, Lalousis, PA, Lavoie, S, Lepage, M, Liebenthal, E, Mervis, J, Murty, V, Nicholas, SC, Ning, L, Penzel, N, Poldrack, R, Polosecki, P, Pratt, DN, Rabin, R, Eichi, HR, Rathi, Y, Reichenberg, A, Reinen, J, Rogers, J, Ruiz-Yu, B, Scott, I, Seitz-Holland, J, Srihari, VH, Srivastava, A, Thompson, A, Turetsky, BI, Walsh, BC, Whitford, T, Wigman, JTW, Yao, B, Yuen, HP, Ahmed, U, Byun, AJS, Chung, Y, Do, K, Hendricks, L, Huynh, K, Jeffries, C, Lane, E, Langholm, C, Lin, E, Mantua, V, Santorelli, G, Ruparel, K, Zoupou, E, Adasme, T, Addamo, L, Adery, L, Ali, M, Auther, A, Aversa, S, Baek, S-H, Bates, K, Bathery, A, Bayer, JMM, Beedham, R, Bilgrami, Z, Birch, S, Bonoldi, I, Borders, O, Borgatti, R, Brown, L, Bruna, A, Carrington, H, Castillo-Passi, RI, Chen, J, Cheng, N, Ching, AE, Clifford, C, Colton, B-L, Contreras, P, Corral, S, Damiani, S, Done, M, Estrade, A, Etuka, BA, Formica, M, Furlan, R, Geljic, M, Germano, C, Getachew, R, Goncalves, M, Haidar, A, Hartmann, J, Jo, A, John, O, Kerins, S, Kerr, M, Kesselring, I, Kim, H, Kim, N, Kinney, K, Krcmar, M, Kotler, E, Lafanechere, M, Lee, C, Llerena, J, Markiewicz, C, Matnejl, P, Maturana, A, Mavambu, A, Mayol-Troncoso, R, McDonnell, A, McGowan, A, McLaughlin, D, McIlhenny, R, McQueen, B, Mebrahtu, Y, Mensi, M, Hui, CLM, Suen, YN, Wong, SMY, Morrell, N, Omar, M, Partridge, A, Phassouliotis, C, Pichiecchio, A, Politi, P, Porter, C, Provenzani, U, Prunier, N, Raj, J, Ray, S, Rayner, V, Reyes, M, Reynolds, K, Rush, S, Salinas, C, Shetty, J, Snowball, C, Tod, S, Turra-Farina, G, Valle, D, Veale, S, Whitson, S, Wickham, A, Youn, S, Zamorano, F, Zavaglia, E, Zinberg, J, Woods, SW, Shenton, ME, Wannan, CMJ, Nelson, B, Addington, J, Allott, K, Anticevic, A, Arango, C, Baker, JT, Bearden, CE, Billah, T, Bouix, S, Broome, MR, Buccilli, K, Cadenhead, KS, Calkins, ME, Cannon, TD, Cecci, G, Chen, EYH, Cho, KIK, Choi, J, Clark, SR, Coleman, MJ, Conus, P, Corcoran, CM, Cornblatt, BA, Diaz-Caneja, CM, Dwyer, D, Ebdrup, BH, Ellman, LM, Fusar-Poli, P, Galindo, L, Gaspar, PA, Gerber, C, Glenthoj, LB, Glynn, R, Harms, MP, Horton, LE, Kahn, RS, Kambeitz, J, Kambeitz-Ilankovic, L, Kane, JM, Kapur, T, Keshavan, MS, Kim, S-W, Koutsouleris, N, Kubicki, M, Kwon, JS, Langbein, K, Lewandowski, KE, Light, GA, Mamah, D, Marcy, PJ, Mathalon, DH, McGorry, PD, Mittal, VA, Nordentoft, M, Nunez, A, Pasternak, O, Pearlson, GD, Perez, J, Perkins, DO, Powers, AR, Roalf, DR, Sabb, FW, Schiffman, J, Shah, JL, Smesny, S, Spark, J, Stone, WS, Strauss, GP, Tamayo, Z, Torous, J, Upthegrove, R, Vangel, M, Verma, S, Wang, J, Winter-van Rossum, I, Wolf, DH, Wolff, P, Wood, SJ, Yung, AR, Agurto, C, Alvarez-Jimenez, M, Amminger, P, Armando, M, Asgari-Targhi, A, Cahill, J, Carrion, RE, Castro, E, Cetin-Karayumak, S, Chakravarty, MM, Cho, YT, Cotter, D, D'Alfonso, S, Ennis, M, Fadnavis, S, Fonteneau, C, Gao, C, Gupta, T, Gur, RE, Gur, RC, Hamilton, HK, Hoftman, GD, Jacobs, GR, Jarcho, J, Ji, JL, Kohler, CG, Lalousis, PA, Lavoie, S, Lepage, M, Liebenthal, E, Mervis, J, Murty, V, Nicholas, SC, Ning, L, Penzel, N, Poldrack, R, Polosecki, P, Pratt, DN, Rabin, R, Eichi, HR, Rathi, Y, Reichenberg, A, Reinen, J, Rogers, J, Ruiz-Yu, B, Scott, I, Seitz-Holland, J, Srihari, VH, Srivastava, A, Thompson, A, Turetsky, BI, Walsh, BC, Whitford, T, Wigman, JTW, Yao, B, Yuen, HP, Ahmed, U, Byun, AJS, Chung, Y, Do, K, Hendricks, L, Huynh, K, Jeffries, C, Lane, E, Langholm, C, Lin, E, Mantua, V, Santorelli, G, Ruparel, K, Zoupou, E, Adasme, T, Addamo, L, Adery, L, Ali, M, Auther, A, Aversa, S, Baek, S-H, Bates, K, Bathery, A, Bayer, JMM, Beedham, R, Bilgrami, Z, Birch, S, Bonoldi, I, Borders, O, Borgatti, R, Brown, L, Bruna, A, Carrington, H, Castillo-Passi, RI, Chen, J, Cheng, N, Ching, AE, Clifford, C, Colton, B-L, Contreras, P, Corral, S, Damiani, S, Done, M, Estrade, A, Etuka, BA, Formica, M, Furlan, R, Geljic, M, Germano, C, Getachew, R, Goncalves, M, Haidar, A, Hartmann, J, Jo, A, John, O, Kerins, S, Kerr, M, Kesselring, I, Kim, H, Kim, N, Kinney, K, Krcmar, M, Kotler, E, Lafanechere, M, Lee, C, Llerena, J, Markiewicz, C, Matnejl, P, Maturana, A, Mavambu, A, Mayol-Troncoso, R, McDonnell, A, McGowan, A, McLaughlin, D, McIlhenny, R, McQueen, B, Mebrahtu, Y, Mensi, M, Hui, CLM, Suen, YN, Wong, SMY, Morrell, N, Omar, M, Partridge, A, Phassouliotis, C, Pichiecchio, A, Politi, P, Porter, C, Provenzani, U, Prunier, N, Raj, J, Ray, S, Rayner, V, Reyes, M, Reynolds, K, Rush, S, Salinas, C, Shetty, J, Snowball, C, Tod, S, Turra-Farina, G, Valle, D, Veale, S, Whitson, S, Wickham, A, Youn, S, Zamorano, F, Zavaglia, E, Zinberg, J, Woods, SW, and Shenton, ME

Abstract

This article describes the rationale, aims, and methodology of the Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ). This is the largest international collaboration to date that will develop algorithms to predict trajectories and outcomes of individuals at clinical high risk (CHR) for psychosis and to advance the development and use of novel pharmacological interventions for CHR individuals. We present a description of the participating research networks and the data processing analysis and coordination center, their processes for data harmonization across 43 sites from 13 participating countries (recruitment across North America, Australia, Europe, Asia, and South America), data flow and quality assessment processes, data analyses, and the transfer of data to the National Institute of Mental Health (NIMH) Data Archive (NDA) for use by the research community. In an expected sample of approximately 2000 CHR individuals and 640 matched healthy controls, AMP SCZ will collect clinical, environmental, and cognitive data along with multimodal biomarkers, including neuroimaging, electrophysiology, fluid biospecimens, speech and facial expression samples, novel measures derived from digital health technologies including smartphone-based daily surveys, and passive sensing as well as actigraphy. The study will investigate a range of clinical outcomes over a 2-year period, including transition to psychosis, remission or persistence of CHR status, attenuated positive symptoms, persistent negative symptoms, mood and anxiety symptoms, and psychosocial functioning. The global reach of AMP SCZ and its harmonized innovative methods promise to catalyze the development of new treatments to address critical unmet clinical and public health needs in CHR individuals.

Published
2024

31. Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ):Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for Psychosis

Author

Wannan, Cassandra M.J., Nelson, Barnaby, Addington, Jean, Allott, Kelly, Anticevic, Alan, Arango, Celso, Baker, Justin T., Bearden, Carrie E., Billah, Tashrif, Bouix, Sylvain, Broome, Matthew R., Buccilli, Kate, Cadenhead, Kristin S., Calkins, Monica E., Cannon, Tyrone D., Cecci, Guillermo, Chen, Eric Yu Hai, Cho, Kang Ik K., Choi, Jimmy, Clark, Scott R., Coleman, Michael J., Conus, Philippe, Corcoran, Cheryl M., Cornblatt, Barbara A., Diaz-Caneja, Covadonga M., Dwyer, Dominic, Ebdrup, Bjørn H., Ellman, Lauren M., Fusar-Poli, Paolo, Galindo, Liliana, Gaspar, Pablo A., Gerber, Carla, Glenthøj, Louise Birkedal, Glynn, Robert, Harms, Michael P., Horton, Leslie E., Kahn, René S., Kambeitz, Joseph, Kambeitz-Ilankovic, Lana, Kane, John M., Kapur, Tina, Keshavan, Matcheri S., Kim, Sung Wan, Koutsouleris, Nikolaos, Kubicki, Marek, Kwon, Jun Soo, Langbein, Kerstin, Lewandowski, Kathryn E., Light, Gregory A., Mamah, Daniel, Marcy, Patricia J., Mathalon, Daniel H., McGorry, Patrick D., Mittal, Vijay A., Nordentoft, Merete, Nunez, Angela, Pasternak, Ofer, Pearlson, Godfrey D., Perez, Jesus, Perkins, Diana O., Powers, Albert R., Roalf, David R., Sabb, Fred W., Schiffman, Jason, Shah, Jai L., Smesny, Stefan, Spark, Jessica, Stone, William S., Strauss, Gregory P., Tamayo, Zailyn, Torous, John, Upthegrove, Rachel, Vangel, Mark, Verma, Swapna, Wang, Jijun, Rossum, Inge Winter van, Wolf, Daniel H., Wolff, Phillip, Wood, Stephen J., Yung, Alison R., Agurto, Carla, Alvarez-Jimenez, Mario, Amminger, Paul, Armando, Marco, Asgari-Targhi, Ameneh, Cahill, John, Carrión, Ricardo E., Castro, Eduardo, Cetin-Karayumak, Suheyla, Mallar Chakravarty, M., Cho, Youngsun T., Cotter, David, D'Alfonso, Simon, Ennis, Michaela, Fadnavis, Shreyas, Fonteneau, Clara, Gao, Caroline, Gupta, Tina, Gur, Raquel E., Gur, Ruben C., Hamilton, Holly K., Hoftman, Gil D., Jacobs, Grace R., Jarcho, Johanna, Ji, Jie Lisa, Kohler, Christian G., Lalousis, Paris Alexandros, Lavoie, Suzie, Lepage, Martin, Liebenthal, Einat, Mervis, Josh, Murty, Vishnu, Nicholas, Spero C., Ning, Lipeng, Penzel, Nora, Poldrack, Russell, Polosecki, Pablo, Pratt, Danielle N., Rabin, Rachel, Rahimi Eichi, Habiballah, Rathi, Yogesh, Reichenberg, Avraham, Reinen, Jenna, Rogers, Jack, Ruiz-Yu, Bernalyn, Scott, Isabelle, Seitz-Holland, Johanna, Srihari, Vinod H., Srivastava, Agrima, Thompson, Andrew, Turetsky, Bruce I., Walsh, Barbara C., Whitford, Thomas, Wigman, Johanna T.W., Yao, Beier, Yuen, Hok Pan, Ahmed, Uzair, Byun, Andrew Jin Soo, Chung, Yoonho, Do, Kim, Hendricks, Larry, Huynh, Kevin, Jeffries, Clark, Lane, Erlend, Langholm, Carsten, Lin, Eric, Mantua, Valentina, Santorelli, Gennarina, Ruparel, Kosha, Zoupou, Eirini, Adasme, Tatiana, Addamo, Lauren, Adery, Laura, Ali, Munaza, Auther, Andrea, Aversa, Samantha, Baek, Seon Hwa, Bates, Kelly, Bathery, Alyssa, Bayer, Johanna M.M., Beedham, Rebecca, Bilgrami, Zarina, Birch, Sonia, Bonoldi, Ilaria, Borders, Owen, Borgatti, Renato, Brown, Lisa, Bruna, Alejandro, Carrington, Holly, Castillo-Passi, Rolando I., Chen, Justine, Cheng, Nicholas, Ching, Ann Ee, Clifford, Chloe, Colton, Beau Luke, Contreras, Pamela, Corral, Sebastián, Damiani, Stefano, Done, Monica, Estradé, Andrés, Etuka, Brandon Asika, Formica, Melanie, Furlan, Rachel, Geljic, Mia, Germano, Carmela, Getachew, Ruth, Goncalves, Mathias, Haidar, Anastasia, Hartmann, Jessica, Jo, Anna, John, Omar, Kerins, Sarah, Kerr, Melissa, Kesselring, Irena, Kim, Honey, Kim, Nicholas, Kinney, Kyle, Krcmar, Marija, Kotler, Elana, Lafanechere, Melanie, Lee, Clarice, Llerena, Joshua, Markiewicz, Christopher, Matnejl, Priya, Maturana, Alejandro, Mavambu, Aissata, Mayol-Troncoso, Rocío, McDonnell, Amelia, McGowan, Alessia, McLaughlin, Danielle, McIlhenny, Rebecca, McQueen, Brittany, Mebrahtu, Yohannes, Mensi, Martina, Hui, Christy Lai Ming, Suen, Yi Nam, Wong, Stephanie Ming Yin, Morrell, Neal, Omar, Mariam, Partridge, Alice, Phassouliotis, Christina, Pichiecchio, Anna, Politi, Pierluigi, Porter, Christian, Provenzani, Umberto, Prunier, Nicholas, Raj, Jasmine, Ray, Susan, Rayner, Victoria, Reyes, Manuel, Reynolds, Kate, Rush, Sage, Salinas, Cesar, Shetty, Jashmina, Snowball, Callum, Tod, Sophie, Turra-Fariña, Gabriel, Valle, Daniela, Veale, Simone, Whitson, Sarah, Wickham, Alana, Youn, Sarah, Zamorano, Francisco, Zavaglia, Elissa, Zinberg, Jamie, Woods, Scott W., Shenton, Martha E., Wannan, Cassandra M.J., Nelson, Barnaby, Addington, Jean, Allott, Kelly, Anticevic, Alan, Arango, Celso, Baker, Justin T., Bearden, Carrie E., Billah, Tashrif, Bouix, Sylvain, Broome, Matthew R., Buccilli, Kate, Cadenhead, Kristin S., Calkins, Monica E., Cannon, Tyrone D., Cecci, Guillermo, Chen, Eric Yu Hai, Cho, Kang Ik K., Choi, Jimmy, Clark, Scott R., Coleman, Michael J., Conus, Philippe, Corcoran, Cheryl M., Cornblatt, Barbara A., Diaz-Caneja, Covadonga M., Dwyer, Dominic, Ebdrup, Bjørn H., Ellman, Lauren M., Fusar-Poli, Paolo, Galindo, Liliana, Gaspar, Pablo A., Gerber, Carla, Glenthøj, Louise Birkedal, Glynn, Robert, Harms, Michael P., Horton, Leslie E., Kahn, René S., Kambeitz, Joseph, Kambeitz-Ilankovic, Lana, Kane, John M., Kapur, Tina, Keshavan, Matcheri S., Kim, Sung Wan, Koutsouleris, Nikolaos, Kubicki, Marek, Kwon, Jun Soo, Langbein, Kerstin, Lewandowski, Kathryn E., Light, Gregory A., Mamah, Daniel, Marcy, Patricia J., Mathalon, Daniel H., McGorry, Patrick D., Mittal, Vijay A., Nordentoft, Merete, Nunez, Angela, Pasternak, Ofer, Pearlson, Godfrey D., Perez, Jesus, Perkins, Diana O., Powers, Albert R., Roalf, David R., Sabb, Fred W., Schiffman, Jason, Shah, Jai L., Smesny, Stefan, Spark, Jessica, Stone, William S., Strauss, Gregory P., Tamayo, Zailyn, Torous, John, Upthegrove, Rachel, Vangel, Mark, Verma, Swapna, Wang, Jijun, Rossum, Inge Winter van, Wolf, Daniel H., Wolff, Phillip, Wood, Stephen J., Yung, Alison R., Agurto, Carla, Alvarez-Jimenez, Mario, Amminger, Paul, Armando, Marco, Asgari-Targhi, Ameneh, Cahill, John, Carrión, Ricardo E., Castro, Eduardo, Cetin-Karayumak, Suheyla, Mallar Chakravarty, M., Cho, Youngsun T., Cotter, David, D'Alfonso, Simon, Ennis, Michaela, Fadnavis, Shreyas, Fonteneau, Clara, Gao, Caroline, Gupta, Tina, Gur, Raquel E., Gur, Ruben C., Hamilton, Holly K., Hoftman, Gil D., Jacobs, Grace R., Jarcho, Johanna, Ji, Jie Lisa, Kohler, Christian G., Lalousis, Paris Alexandros, Lavoie, Suzie, Lepage, Martin, Liebenthal, Einat, Mervis, Josh, Murty, Vishnu, Nicholas, Spero C., Ning, Lipeng, Penzel, Nora, Poldrack, Russell, Polosecki, Pablo, Pratt, Danielle N., Rabin, Rachel, Rahimi Eichi, Habiballah, Rathi, Yogesh, Reichenberg, Avraham, Reinen, Jenna, Rogers, Jack, Ruiz-Yu, Bernalyn, Scott, Isabelle, Seitz-Holland, Johanna, Srihari, Vinod H., Srivastava, Agrima, Thompson, Andrew, Turetsky, Bruce I., Walsh, Barbara C., Whitford, Thomas, Wigman, Johanna T.W., Yao, Beier, Yuen, Hok Pan, Ahmed, Uzair, Byun, Andrew Jin Soo, Chung, Yoonho, Do, Kim, Hendricks, Larry, Huynh, Kevin, Jeffries, Clark, Lane, Erlend, Langholm, Carsten, Lin, Eric, Mantua, Valentina, Santorelli, Gennarina, Ruparel, Kosha, Zoupou, Eirini, Adasme, Tatiana, Addamo, Lauren, Adery, Laura, Ali, Munaza, Auther, Andrea, Aversa, Samantha, Baek, Seon Hwa, Bates, Kelly, Bathery, Alyssa, Bayer, Johanna M.M., Beedham, Rebecca, Bilgrami, Zarina, Birch, Sonia, Bonoldi, Ilaria, Borders, Owen, Borgatti, Renato, Brown, Lisa, Bruna, Alejandro, Carrington, Holly, Castillo-Passi, Rolando I., Chen, Justine, Cheng, Nicholas, Ching, Ann Ee, Clifford, Chloe, Colton, Beau Luke, Contreras, Pamela, Corral, Sebastián, Damiani, Stefano, Done, Monica, Estradé, Andrés, Etuka, Brandon Asika, Formica, Melanie, Furlan, Rachel, Geljic, Mia, Germano, Carmela, Getachew, Ruth, Goncalves, Mathias, Haidar, Anastasia, Hartmann, Jessica, Jo, Anna, John, Omar, Kerins, Sarah, Kerr, Melissa, Kesselring, Irena, Kim, Honey, Kim, Nicholas, Kinney, Kyle, Krcmar, Marija, Kotler, Elana, Lafanechere, Melanie, Lee, Clarice, Llerena, Joshua, Markiewicz, Christopher, Matnejl, Priya, Maturana, Alejandro, Mavambu, Aissata, Mayol-Troncoso, Rocío, McDonnell, Amelia, McGowan, Alessia, McLaughlin, Danielle, McIlhenny, Rebecca, McQueen, Brittany, Mebrahtu, Yohannes, Mensi, Martina, Hui, Christy Lai Ming, Suen, Yi Nam, Wong, Stephanie Ming Yin, Morrell, Neal, Omar, Mariam, Partridge, Alice, Phassouliotis, Christina, Pichiecchio, Anna, Politi, Pierluigi, Porter, Christian, Provenzani, Umberto, Prunier, Nicholas, Raj, Jasmine, Ray, Susan, Rayner, Victoria, Reyes, Manuel, Reynolds, Kate, Rush, Sage, Salinas, Cesar, Shetty, Jashmina, Snowball, Callum, Tod, Sophie, Turra-Fariña, Gabriel, Valle, Daniela, Veale, Simone, Whitson, Sarah, Wickham, Alana, Youn, Sarah, Zamorano, Francisco, Zavaglia, Elissa, Zinberg, Jamie, Woods, Scott W., and Shenton, Martha E.

Abstract

This article describes the rationale, aims, and methodology of the Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ). This is the largest international collaboration to date that will develop algorithms to predict trajectories and outcomes of individuals at clinical high risk (CHR) for psychosis and to advance the development and use of novel pharmacological interventions for CHR individuals. We present a description of the participating research networks and the data processing analysis and coordination center, their processes for data harmonization across 43 sites from 13 participating countries (recruitment across North America, Australia, Europe, Asia, and South America), data flow and quality assessment processes, data analyses, and the transfer of data to the National Institute of Mental Health (NIMH) Data Archive (NDA) for use by the research community. In an expected sample of approximately 2000 CHR individuals and 640 matched healthy controls, AMP SCZ will collect clinical, environmental, and cognitive data along with multimodal biomarkers, including neuroimaging, electrophysiology, fluid biospecimens, speech and facial expression samples, novel measures derived from digital health technologies including smartphone-based daily surveys, and passive sensing as well as actigraphy. The study will investigate a range of clinical outcomes over a 2-year period, including transition to psychosis, remission or persistence of CHR status, attenuated positive symptoms, persistent negative symptoms, mood and anxiety symptoms, and psychosocial functioning. The global reach of AMP SCZ and its harmonized innovative methods promise to catalyze the development of new treatments to address critical unmet clinical and public health needs in CHR individuals., This article describes the rationale, aims, and methodology of the Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ). This is the largest international collaboration to date that will develop algorithms to predict trajectories and outcomes of individuals at clinical high risk (CHR) for psychosis and to advance the development and use of novel pharmacological interventions for CHR individuals. We present a description of the participating research networks and the data processing analysis and coordination center, their processes for data harmonization across 43 sites from 13 participating countries (recruitment across North America, Australia, Europe, Asia, and South America), data flow and quality assessment processes, data analyses, and the transfer of data to the National Institute of Mental Health (NIMH) Data Archive (NDA) for use by the research community. In an expected sample of approximately 2000 CHR individuals and 640 matched healthy controls, AMP SCZ will collect clinical, environmental, and cognitive data along with multimodal biomarkers, including neuroimaging, electrophysiology, fluid biospecimens, speech and facial expression samples, novel measures derived from digital health technologies including smartphone-based daily surveys, and passive sensing as well as actigraphy. The study will investigate a range of clinical outcomes over a 2-year period, including transition to psychosis, remission or persistence of CHR status, attenuated positive symptoms, persistent negative symptoms, mood and anxiety symptoms, and psychosocial functioning. The global reach of AMP SCZ and its harmonized innovative methods promise to catalyze the development of new treatments to address critical unmet clinical and public health needs in CHR individuals.

Published
2024

34. A coherent polarimeter array for the Large Scale Polarization Explorer balloon experiment

Author

Bersanelli, M., Mennella, A., Morgante, G., Zannoni, M., Addamo, G., Baschirotto, A., Battaglia, P., Baù, A., Cappellini, B., Cavaliere, F., Cuttaia, F., Del Torto, F., Donzelli, S., Farooqui, Z., Frailis, M., Franceschet, C., Franceschi, E., Gaier, T., Galeotta, S., Gervasi, M., Gregorio, A., Kangaslahti, P., Krachmalnicoff, N., Lawrence, C., Maggio, G., Mainini, R., Maino, D., Mandolesi, N., Paroli, B., Passerini, A., Peverini, O. A., Poli, S., Ricciardi, S., Rossetti, M., Sandri, M., Seiffert, M., Stringhetti, L., Tartari, A., Tascone, R., Tavagnacco, D., Terenzi, L., Tomasi, M., Tommasi, E., Villa, F., Virone, G., and Zacchei, A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We discuss the design and expected performance of STRIP (STRatospheric Italian Polarimeter), an array of coherent receivers designed to fly on board the LSPE (Large Scale Polarization Explorer) balloon experiment. The STRIP focal plane array comprises 49 elements in Q band and 7 elements in W-band using cryogenic HEMT low noise amplifiers and high performance waveguide components. In operation, the array will be cooled to 20 K and placed in the focal plane of a $\sim 0.6$ meter telescope providing an angular resolution of $\sim1.5$ degrees. The LSPE experiment aims at large scale, high sensitivity measurements of CMB polarization, with multi-frequency deep measurements to optimize component separation. The STRIP Q-band channel is crucial to accurately measure and remove the synchrotron polarized component, while the W-band channel, together with a bolometric channel at the same frequency, provides a crucial cross-check for systematic effects., Comment: In press on the Proceedings of the SPIE Conference Astronomical Telescopes + instrumentation 2012, Amsterdam, paper 8446-279

Published
2012
Full Text
View/download PDF

38. Tagungsbericht zur ersten Jahrestagung des Netzwerks Kriminologie NRW vom 27. bis 29.03.2019 an der Universität Siegen

Author

Lina Addamo, Julia Blum, Vanessa Dobbener, Kira Grebing, Julian Simon, and Pelin Topaktas

Subjects
Law, Criminal law and procedure, K5000-5582
Abstract

Kriminalität konstituiert sich in Diskursen und Praktiken. In den sozialen Arenen entwickeln sich wirkmächtige Bedeutungsaufladungen, die in Bezug auf das, was aktuell unter Kriminalität gefasst wird, bearbeitet werden: von politischen Entscheidungen zur Förderpraxis in der Sicherheitsforschung über Präventions- und Interventionsprogramme bis zu den Bedingungen und Eigensinnigkeiten institutioneller Praxis. Diese Vielfalt und Verwobenheit standen im Fokus der ersten Tagung des Netzwerks „Kriminologie in NRW“. Hierbei wurde der Raum insbesondere Nachwuchswissenschaftler*innen eröffnet, ihre Forschungsvorhaben in ganz unterschiedlichen Stadien zu präsentieren und interdisziplinäre Rückmeldungen zu erhalten. Neben der Nachwuchsförderung ist ein zentrales Anliegen des Netzwerks, den Austausch zwischen Forschung, Lehre und Praxis anzuregen, ihre vielfältigen Konzepte zu bündeln und Aktivitäten sichtbar zu machen.

Published
2019
Full Text
View/download PDF

41. Genetic Conservation Management of Marine Resources and Ecosystems of Patagonian Fjords

Author

Anna Maria Addamo, Serena Zaccara, Günter Försterra, Juan Höfer, Ricardo García-Jiménez, Giuseppe Crosa, and Annie Machordom

Subjects
cold water corals, genetic structure, oceanographic conditions, conservation, aquaculture sustainability, Patagonian fjord region, Science, General. Including nature conservation, geographical distribution, QH1-199.5
Abstract

The Chilean fjord region includes many remote and poorly known areas where management plans for the marine living resources and conservation strategies are urgently needed. Few data are available about the spatial distribution of its marine invertebrate fauna, prevalently influenced by complex interactions between biotic and abiotic factors, animal behavior and human activities. Patagonian fjords are a hotspot for finfish aquaculture, elevating Chile to the world’s second producer of farmed salmon, after Norway, a condition that emphasizes the necessity to develop strategies for a sustainable aquaculture management. The present study focuses on the emblematic cold-water coral Desmophyllum dianthus, dwelling the Comau Fjord from shallow to deep waters, with the aim to illustrate population structure, demography and adaptation of the species and its potential use for the development of a sustainable conservation and management plan for human activities. The analyses of microsatellite loci of D. dianthus individuals from four sampling localities along horizontal and vertical gradients of Comau Fjord, lead to identify them as a panmictic population. The results also contributed to consider a careful examination of the synchrony between the temporal and spatial variations of environmental factors and the biological cycle of the species as key role player in the inference of autecology of the species. The discussion stresses the importance of molecular analyses as extremely helpful tools for studies focusing on remote areas and non-model organisms, where logistic difficulties and limited scientific knowledge hamper a better management and conservation of marine resources, and in particular the relevance of multidisciplinary approaches to reduce the extensive knowledge gap on the remote fjord ecosystems of Patagonia. This study also highlights the importance of oceanographic information in the entire process of the analyses and interpretation of genetic results.

Published
2021
Full Text
View/download PDF

42. The Origin and Correlated Evolution of Symbiosis and Coloniality in Scleractinian Corals

Author

Ana Navarro Campoy, Anna Maria Addamo, Annie Machordom, Andrew Meade, Marcelo M. Rivadeneira, Cristián E. Hernández, and Chris Venditti

Subjects
Scleractinia, symbiosis, coloniality, zooxanthellae, correlated evolution, deep-sea, Science, General. Including nature conservation, geographical distribution, QH1-199.5
Abstract

Symbiosis and coloniality are ecologically important traits for corals of the order Scleractinia. Symbiotic (zooxanthellate) species are highly successful in shallow waters of tropical and subtropical seas and most of them are colonial. On the other hand, azooxanthellate species present wide distribution ranges and expand to the deep-sea at more than 6,000 m depth. These are mostly solitary, with only few species colonial that form extensive deep reefs. Each ecologically distinctive group encompasses half of the biodiversity of the order and they are not grouped into differentiated monophyletic clades. Paleontologists and evolutionary biologists have debated for decades whether modern scleractinian corals have evolved from symbiotic or colonial ancestors and how these traits have evolved and being involved in the diversification process in corals. Previous comparative analyses throw evidence in favor of coevolution of these characters and toward repetitive loss of symbiosis and coloniality. Nevertheless, the discovery of the origin of the group deep in the Paleozoic, with a deep divergent clade composed of only azooxanthellate corals has questioned these findings. With this work, we disentangle the patterns in the evolution of symbiosis and coloniality, testing if they are correlated and if they follow a gradual or episodic mode of evolution. To this end, we first produce the most complete time-calibrated phylogenetic tree for the order Scleractinia, including new sequences of never-before sampled species and genera. These novel sequences contribute to alleviate the current molecular under sampling of azooxanthellate species. Incorporating phylogenetic uncertainty, we obtained strong evidence in favor of a correlated and episodic model of evolution. This model led to the inference of an azooxanthellate and solitary most recent ancestor of scleractinians. Transition rates between the four different combinations of the two traits showed that while coloniality is gained and lost multiple times, symbiosis first appears around 282 Ma and is never lost. Also, coloniality seems to have appeared before symbiosis in azooxanthellate lineages. Thus, azooxanthellate corals, and especially colonial lineages, have been acting as a source of biodiversity for shallow zooxanthellate coral communities, highlighting the uniqueness of shallow and deep species and the need to preserve them.

Published
2020
Full Text
View/download PDF

44. RF Characterization of 3D-Printed Dielectric Materials

Author

Lumia, Mauro, primary, Addamo, Giuseppe, additional, Virone, Giuseppe, additional, Peverini, Oscar Antonio, additional, Paonessa, Fabio, additional, Rabitsch, Julia, additional, Mele, Marcello, additional, Calignano, Flaviana, additional, Manfredi, Diego, additional, and Bouzekri, Oilid, additional

Published
2023
Full Text
View/download PDF

47. Unravelling the relationships among Madrepora Linnaeus, 1758, Oculina Lamark, 1816 and Cladocora Ehrenberg, 1834 (Cnidaria: Anthozoa: Scleractinia).

Author

Addamo, Anna M., Modrell, Melinda S., Taviani, Marco, and Machordom, Annie

Subjects
*ACROPORA, *SCLERACTINIA, *ANTHOZOA, *DEEP-sea corals, *CORALS, *CNIDARIA
Abstract

Despite the widespread use of integrative taxonomic approaches, many scleractinian coral genera and species remain grouped in polyphyletic families, classified as incertae sedis or simply understudied. Oculinidae Gray, 1847 represents a family for which many taxonomic questions remain unresolved, particularly those related to some of the current genera, such as Oculina Lamark, 1816 or recently removed genera, including Cladocora Ehrenberg, 1834 and Madrepora Linnaeus, 1758. Cladocora is currently assigned to the family Cladocoridae Milne Edwards & Haime, 1857 and a new family, Bathyporidae Kitahara, Capel, Zilberberg & Cairns, 2024, was recently raised to accommodate Madrepora. However, the name Bathyporidae is not valid because this was not formed on the basis of a type genus name. To resolve taxonomic questions related to these three genera, the evolutionary relationships are explored through phylogenetic analyses of 18 molecular markers. The results of these analyses support a close relationship between the species Oculina patagonica and Cladocora caespitosa, indicating that these may belong to the same family (and possibly genus), and highlighting the need for detailed revisions of Oculina and Cladocora. By contrast, a distant relationship is found between these two species and Madrepora oculata, with the overall evidence supporting the placement of Madrepora in the resurrected family Madreporidae Ehrenberg, 1834. This study advances our knowledge of coral systematics and highlights the need for a comprehensive review of the genera Oculina, Cladocora and Madrepora. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

49. Enhanced Efficiency and Reduced Side Lobe Level Convex Conformal Reflectarray

Author

Michele Beccaria, Giuseppe Addamo, Mario Orefice, Oscar Peverini, Diego Manfredi, Flaviana Calignano, Giuseppe Virone, and Paola Pirinoli

Subjects
reflectarray, conformal reflectarray, millimeter wave, 3D printing, feed horn, selective laser melting, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999
Abstract

In this work, the design of a convex conformal reflectarray (CRA), suitable to be used for high gain on board antenna in mobile communication systems, is presented. The reflector is not planar, as in usual reflectarray configurations, but the re-radiating elements are printed on a surface conformed to a cylinder to mimic a curved surface, such as the fuselage of an airplane, on which the reflectarray could be mounted. To compensate for the loss in efficiency due to the curvature, an ad hoc feed is designed; the results obtained with the simulation of the entire structure and the measurements of its prototype prove the effectiveness of the design procedure and its capability in enhancing the CRA features, in comparison with similar but more conventional solutions.

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results