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1. Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial

Author

Perera, Divaka, Clapp, Brian, Prendergast, Bernard, Pavlidis, Antonis, Wragg, Andrew, Byrne, Jonathan, Stephens, Nigel, Rosser, Gareth, Wood, Darryl, Bell, Robert, Kurbaan, Arvinder, Ozkor, Muhiddin, Lampard, Anthony, Papadopoulos, Desiree, Hughes, Johanna, Pendolino, Valentina, Shaw, Joanna, Bannister, Clara, Long, Amy, Kearney, Justin, Palti, Gabriel, Ritches-Price, Joanne, Whitbread, Mark, Adamson, Dawn, Blows, Lucy, Brown, Martin, Lane, Garth, Connor, Michael, Muir, Keith, Chamberlain, Douglas, Morris, Tim, Kwok, Matthew, Knight, Megan, Jerome, Lauren, Nijjer, Sukhjinder, Das, Rita, Sidney, Therese, Bogle, Richard, Roberts, Patrick, Webb, Ian, Spencer, Oliver, Petzer, Edward, Khan, Masood, Marciniak, Maciej, De Belder, Mark, Stables, Rod, Curzen, Nick, Mamas, Mamas, Patterson, Tiffany, Perkins, Gavin D, Perkins, Alexander, Clayton, Tim, Evans, Richard, Dodd, Matthew, Robertson, Steven, Wilson, Karen, Mellett-Smith, Adam, Fothergill, Rachael T, McCrone, Paul, Dalby, Miles, MacCarthy, Philip, Firoozi, Sam, Malik, Iqbal, Rakhit, Roby, Jain, Ajay, Nolan, Jerry P, and Redwood, Simon R

Published
2023
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2. Cardiac implantable electronic devices in pregnancy: A position statement.

Author

Castleman, James, Curtis, Stephanie, Fox, Caroline, Hudsmith, Lucy, Nolan, Lynn, Geoghegan, James, Metodiev, Yavor, Roberts, Eleri, Morse, Lucy, Nisbet, Ashley, Foley, Paul, Wright, Ian, Thomas, Honey, Morris, Katie, Adamson, Dawn, and De Bono, Joseph

Subjects
ELECTRONIC equipment, IMPLANTABLE cardioverter-defibrillators, MATERNAL mortality, PUERPERIUM, PREGNANCY
Abstract

The aim of this document is to provide guidance for the management of women and birthing people with a permanent pacemaker (PPM) or implantable cardioverter defibrillator (ICD). Cardiac devices are becoming more common in obstetric practice and a reference document for contemporary evidence‐based practice is required. Where evidence is limited, expert consensus has established recommendations. The purpose is to improve safety and reduce the risk of adverse events relating to implanted cardiac devices during pregnancy, birth and the postnatal period. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Advancing the access to cardiovascular diagnosis and treatment among women with cardiovascular disease: a joint British Cardiovascular Societies’ consensus document.

Author

Tayal, Upasana, Pompei, Graziella, Wilkinson, Ian, Adamson, Dawn, Sinha, Aish, Hildick-Smith, David, Cubbon, Richard, Garbi, Madalina, Ingram, Thomas E., Colebourn, Claire L., Camm, C. Fielder, Guzik, Tomasz J., Anderson, Lisa, Page, Stephen P., Wicks, Eleanor, Jenkins, Petra, Rosen, Stuart D., Eftychiou, Stavros, Roberts, Eleri, and Eftekhari, Helen

Subjects
MEDICAL personnel, SEX factors in disease, HEART failure, CONGENITAL heart disease, PERIPARTUM cardiomyopathy, HEART valve diseases, HEART diseases in women
Published
2024
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4. Diuretics in pregnancy:Data from the ESC Registry of Pregnancy and Cardiac disease (ROPAC)

Author

van der Zande, Johanna A., Greutmann, Matthias, Tobler, Daniel, Ramlakhan, Karishma P., Cornette, Jerome M.J., Ladouceur, Magalie, Collins, Nicholas, Adamson, Dawn, Paruchuri, Vijaya P., Hall, Roger, Johnson, Mark R., Roos-Hesselink, Jolien W., van der Zande, Johanna A., Greutmann, Matthias, Tobler, Daniel, Ramlakhan, Karishma P., Cornette, Jerome M.J., Ladouceur, Magalie, Collins, Nicholas, Adamson, Dawn, Paruchuri, Vijaya P., Hall, Roger, Johnson, Mark R., and Roos-Hesselink, Jolien W.

Abstract

Aims: Data on diuretic use in pregnancy are limited and inconsistent, and consequently it remains unclear whether they can be used safely. Our study aims to evaluate the perinatal outcomes after in-utero diuretic exposure. Methods and results: The Registry Of Pregnancy And Cardiac disease (ROPAC) is a prospective, global registry of pregnancies in women with heart disease. Outcomes were compared between women who used diuretics during pregnancy versus those who did not. Multivariable regression analysis was used to assess the impact of diuretic use on the occurrence of congenital anomalies and foetal growth. Diuretics were used in 382 (6.7%) of the 5739 ROPAC pregnancies, most often furosemide (86%). Age >35 years (odds ratio [OR] 1.5, 95% confidence interval [CI] 1.2–2.0), other cardiac medication use (OR 5.4, 95% CI 4.2–6.9), signs of heart failure (OR 1.7, 95% CI 1.2–2.2), estimated left ventricular ejection fraction <40% (OR 2.9, 95% CI 2.0–4.2), New York Heart Association class >II (OR 3.4, 95% CI 2.3–5.1), valvular heart disease (OR 6.3, 95% CI 4.7–8.3) and cardiomyopathy (OR 3.9, 95% CI 2.6–5.7) were associated with diuretic use during pregnancy. In multivariable analysis, diuretic use during the first trimester was not significantly associated with foetal or neonatal congenital anomalies (OR 1.3, 95% CI 0.7–2.6), and diuretic use during pregnancy was also not significantly associated with small for gestational age (OR 1.4, 95% CI 1.0–1.9). Conclusions: Our study does not conclusively establish an association between diuretic use during pregnancy and adverse foetal outcomes. Given these findings, it is essential to assess the risk–benefit ratio on an individual basis to guide clinical decisions.

Published
2024

5. Diuretics in pregnancy: Data from the ESC Registry of Pregnancy and Cardiac disease (ROPAC).

Author

van der Zande, Johanna A., Greutmann, Matthias, Tobler, Daniel, Ramlakhan, Karishma P., Cornette, Jerome M. J., Ladouceur, Magalie, Collins, Nicholas, Adamson, Dawn, Paruchuri, Vijaya P., Hall, Roger, Johnson, Mark R., and Roos‐Hesselink, Jolien W.

Subjects
PERIPARTUM cardiomyopathy, HEART failure, SMALL for gestational age, DIURETICS, HEART valve diseases, HEART diseases in women, CARDIOVASCULAR agents
Abstract

Aims: Data on diuretic use in pregnancy are limited and inconsistent, and consequently it remains unclear whether they can be used safely. Our study aims to evaluate the perinatal outcomes after in‐utero diuretic exposure. Methods and results: The Registry Of Pregnancy And Cardiac disease (ROPAC) is a prospective, global registry of pregnancies in women with heart disease. Outcomes were compared between women who used diuretics during pregnancy versus those who did not. Multivariable regression analysis was used to assess the impact of diuretic use on the occurrence of congenital anomalies and foetal growth. Diuretics were used in 382 (6.7%) of the 5739 ROPAC pregnancies, most often furosemide (86%). Age >35 years (odds ratio [OR] 1.5, 95% confidence interval [CI] 1.2–2.0), other cardiac medication use (OR 5.4, 95% CI 4.2–6.9), signs of heart failure (OR 1.7, 95% CI 1.2–2.2), estimated left ventricular ejection fraction <40% (OR 2.9, 95% CI 2.0–4.2), New York Heart Association class >II (OR 3.4, 95% CI 2.3–5.1), valvular heart disease (OR 6.3, 95% CI 4.7–8.3) and cardiomyopathy (OR 3.9, 95% CI 2.6–5.7) were associated with diuretic use during pregnancy. In multivariable analysis, diuretic use during the first trimester was not significantly associated with foetal or neonatal congenital anomalies (OR 1.3, 95% CI 0.7–2.6), and diuretic use during pregnancy was also not significantly associated with small for gestational age (OR 1.4, 95% CI 1.0–1.9). Conclusions: Our study does not conclusively establish an association between diuretic use during pregnancy and adverse foetal outcomes. Given these findings, it is essential to assess the risk–benefit ratio on an individual basis to guide clinical decisions. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Best practice recommendations for medically assisted reproduction in patients with known cardiovascular disease or at high risk of cardiovascular disease

Author

English, Kate, primary, Frise, Charlotte, additional, Trinder, Johanna, additional, Cauldwell, Matthew, additional, Simpson, Maggie, additional, Adamson, Dawn, additional, Elton, Chris, additional, Burns, Gwenda, additional, Choudhary, Meenakshi, additional, Nathanson, Mike, additional, Robert, Leema, additional, Moore, Jim, additional, O’Brien, Pat, additional, and Pundir, Jyotsna, additional

Published
2024
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8. Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial

Author

Patterson, Tiffany, primary, Perkins, Gavin D, additional, Perkins, Alexander, additional, Clayton, Tim, additional, Evans, Richard, additional, Dodd, Matthew, additional, Robertson, Steven, additional, Wilson, Karen, additional, Mellett-Smith, Adam, additional, Fothergill, Rachael T, additional, McCrone, Paul, additional, Dalby, Miles, additional, MacCarthy, Philip, additional, Firoozi, Sam, additional, Malik, Iqbal, additional, Rakhit, Roby, additional, Jain, Ajay, additional, Nolan, Jerry P, additional, Redwood, Simon R, additional, Perera, Divaka, additional, Clapp, Brian, additional, Prendergast, Bernard, additional, Pavlidis, Antonis, additional, Wragg, Andrew, additional, Byrne, Jonathan, additional, Stephens, Nigel, additional, Rosser, Gareth, additional, Wood, Darryl, additional, Bell, Robert, additional, Kurbaan, Arvinder, additional, Ozkor, Muhiddin, additional, Lampard, Anthony, additional, Papadopoulos, Desiree, additional, Hughes, Johanna, additional, Pendolino, Valentina, additional, Shaw, Joanna, additional, Bannister, Clara, additional, Long, Amy, additional, Kearney, Justin, additional, Palti, Gabriel, additional, Ritches-Price, Joanne, additional, Whitbread, Mark, additional, Adamson, Dawn, additional, Blows, Lucy, additional, Brown, Martin, additional, Lane, Garth, additional, Connor, Michael, additional, Muir, Keith, additional, Chamberlain, Douglas, additional, Morris, Tim, additional, Kwok, Matthew, additional, Knight, Megan, additional, Jerome, Lauren, additional, Nijjer, Sukhjinder, additional, Das, Rita, additional, Sidney, Therese, additional, Bogle, Richard, additional, Roberts, Patrick, additional, Webb, Ian, additional, Spencer, Oliver, additional, Petzer, Edward, additional, Khan, Masood, additional, Marciniak, Maciej, additional, De Belder, Mark, additional, Stables, Rod, additional, Curzen, Nick, additional, and Mamas, Mamas, additional

Published
2023
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11. Direct current cardioversion in pregnancy: a multicentre study.

Author

Cauldwell, Matthew, Adamson, Dawn, Bhatia, Kaliash, Bhagra, Catriona, Bolger, Aidan, Everett, Thomas, Fox, Caroline, Girling, Joanna, Head, Catherine, English, Kate, Hudsmith, Lucy, James, Rachael, Johnson, Mark, MacKiliop, Lucy, McAuliffe, Fionnuala M., Mariappa, Gayathri, Orchard, Elizabeth, O'Brien, Maggy, Siddiqui, Farah, and Simpson, Lydia

Subjects
*ELECTRIC countershock, *SUPRAVENTRICULAR tachycardia, *FETAL monitoring, *ATRIAL flutter, *PREGNANCY, *PREGNANT women
Abstract

Objective: Direct current cardioversion (DCCV) in pregnancy is rarely required and typically only documented in single case reports or case series. A recent UK confidential enquiry reported on several maternal deaths where appropriate DCCV appeared to have been withheld. Design: Retrospective cohort study. Setting: Seventeen UK and Ireland specialist maternity centres. Sample: Twenty‐seven pregnant women requiring DCCV in pregnancy. Main outcome measures: Maternal and fetal outcomes following DCCV. Results: Twenty‐seven women had a total of 29 DCCVs in pregnancy. Of these, 19 (70%) initial presentations were to Emergency Departments and eight (30%) to maternity settings. There were no maternal deaths. Seventeen of the women (63%) had a prior history of heart disease. Median gestation at DCCV was 28 weeks, median gestation at delivery was 35 weeks, with a live birth in all cases. The abnormal heart rhythms documented at the first cardioversion were atrial fibrillation in 12/27 (44%) cases, atrial flutter in 8/27 (30%), supraventricular tachycardia in 5/27 (19%) and atrial tachycardia in 2/27 (7%). Fetal monitoring was undertaken following DCCV on 14/29 (48%) occasions (10 of 19 (53%) at ≥26 weeks) and on 2/29 (7%) occasions, urgent delivery was required post DCCV. Conclusions: Direct current cardioversion in pregnancy is rarely required but should be undertaken when clinically indicated according to standard algorithms to optimise maternal wellbeing. Once the woman is stable post DCCV, gestation‐relevant fetal monitoring should be undertaken. Maternity units should develop multidisciplinary processes to ensure pregnant women receive the same standard of care as their non‐pregnant counterparts. [ABSTRACT FROM AUTHOR]

Published
2023
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12. Patient experience within the adult congenital heart disease outreach network: a questionnaire-based study

Author

Ooues, Georgina, Clift, Paul, Bowater, Sarah, Arif, Sayqa, Epstein, Andrew, Prasad, Neeraj, Adamson, Dawn, Cummings, Mandy, Spencer, Charles, Woodmansey, Paul, Borley, Jenny, Ingram, Thomas, Morley-Davies, Adrian, Roberts, William, Qureshi, Najmi, Hawkesford, Susan, Pope, Nichola, Anthony, James, Gaffey, Thomas, Thorne, Sara, Hudsmith, Lucy, and On behalf of The West Midlands ACHD Network, UK

Published
2018
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14. Early eplerenone treatment in patients with acute ST-elevation myocardial infarction without heart failure: The Randomized Double-Blind Reminder Study

Author

Montalescot, Gilles, Pitt, Bertram, Lopez de Sa, Esteban, Hamm, Christian W., Flather, Marcus, Verheugt, Freek, Shi, Harry, Turgonyi, Eva, Orri, Miguel, Vincent, John, Zannad, Faiez, Noll, Georg, Weir, Robin, OʼNeill, Blair, Böhm, Michael, Hillis, W. Stuart, Grieve, Andrew, Rouleau, Jean-Lucien, Gerasimos, Filippatos, Fitchett, David, Lepage, Serge, Madan, Minakshi, Sussex, Bruce, Tremblay, Gerald, Welsh, Robert, Wong, Graham, Hutyra, Martin, Kettner, Jiri, Ostadal, Petr, Spinar, Jindrich, Vojacek, Jan, Barboteu, Michel, Collet, Jean-Philippe, Coste, Pierre, Cottin, Yves, Ducos, Dominique, Galinier, Michel, Teiger, Emmanuel, Zemour, Gilles, Bauersachs, Johann, Hambrecht, Rainer, Hauf, Gerhard, Heuer, Hubertus, Mudra, Harald, Münzel, Thomas, Steiner, Stephan, Strasser, Ruth, Sydow, Karsten, Tschöpe, Carsten, Wachter, Rolf, Werner, Nikos, Alexopoulos, Dimitros, Babalis, Dimitrios, Pyrgakis, Vlassios, Dezsi, Csaba, Lupkovics, Geza, Polgar, Peter, Tomcsanyi, Janos, Herrman, J., ten Berg, J.M., Gorny, Jerzy, Kubica, Jacek, Lewczuk, Jerzy, Zmuda, Witold, Hranai, Marian, Kovar, Frantisek, Margoczy, Roman, Micko, Karol, Sumbal, Jaroslav, Genover, Xavier Bosch, Ortiz, Antonio Fernandez, Sala, Miguel Fiol, Garcia, Cosme Garcia, Muñoz, Carlos Perez, Rey Blas, Juan Ramon, Soriano, Franciso Ridocci, Adamson, Dawn, Alamgir, Farqad, Chauhan, Anoop, Lip, Gregory, Martin, Thomas, McCann, Gerry, Newby, David, and Smith, David

Published
2014
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15. Revascularisation or medical therapy in elderly patients with acute anginal syndromes: the RINCAL randomised trial

Author

de Belder, Adam, primary, Myat, Aung, additional, Blaxill, Jonathan, additional, Haworth, Peter, additional, O'Kane, Peter D., additional, Hatrick, Robert, additional, Aggarwal, Rajesh K., additional, Davie, Andrew, additional, Smith, William, additional, Gerber, Robert, additional, Byrne, Jonathan, additional, Adamson, Dawn, additional, Witherow, Fraser, additional, Alsanjari, Osama, additional, Wright, Juliet, additional, Robinson, Derek R., additional, and Hildick-Smith, David, additional

Published
2021
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22. Cardiomyopathies

Author

Adamson, Dawn, primary, Dhanjal, Mandish, additional, and Nelson-Piercy, Catherine, additional

Published
2011
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23. Hypertension

Author

Adamson, Dawn, primary, Dhanjal, Mandish, additional, and Nelson-Piercy, Catherine, additional

Published
2011
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27. Arrhythmias

Author

Adamson, Dawn, primary, Dhanjal, Mandish, additional, and Nelson-Piercy, Catherine, additional

Published
2011
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28. Aortic pathology

Author

Adamson, Dawn, primary, Dhanjal, Mandish, additional, and Nelson-Piercy, Catherine, additional

Published
2011
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42. Physiology

Author

Williams, David, primary, Kenyon, Anna, additional, and Adamson, Dawn, additional

Published
2010
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43. Contributors

Author

Adamson, Dawn, primary, Briley, Annette, additional, Brown, Louise C, additional, Dixon, Peter H, additional, Hardy, Kate, additional, George, Andrew JT, additional, Johnson, Mark R, additional, Kenyon, Anna P, additional, Kumar, Sailesh, additional, Lyall, Fiona, additional, Nama, Vivek, additional, Paterson-Brown, Sara, additional, Ridgway, Geoffrey L, additional, Sebire, Neil J, additional, Shehata, Hassan, additional, Shennan, Andrew, additional, Talbert, David, additional, Taylor, Paul, additional, Trump, Dorothy, additional, and Williams, David, additional

Published
2010
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