3,108 results on '"Adams Scott"'
Search Results
2. Sustainable transformation of end-of-life tyres into value-added products using thermochemical processes
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Han, Bing, Kumar, Dileep, Pei, Yang, Norton, Michael, Adams, Scott D., Khoo, Sui Yang, and Kouzani, Abbas Z.
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- 2024
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3. MedAlign: A Clinician-Generated Dataset for Instruction Following with Electronic Medical Records
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Fleming, Scott L., Lozano, Alejandro, Haberkorn, William J., Jindal, Jenelle A., Reis, Eduardo P., Thapa, Rahul, Blankemeier, Louis, Genkins, Julian Z., Steinberg, Ethan, Nayak, Ashwin, Patel, Birju S., Chiang, Chia-Chun, Callahan, Alison, Huo, Zepeng, Gatidis, Sergios, Adams, Scott J., Fayanju, Oluseyi, Shah, Shreya J., Savage, Thomas, Goh, Ethan, Chaudhari, Akshay S., Aghaeepour, Nima, Sharp, Christopher, Pfeffer, Michael A., Liang, Percy, Chen, Jonathan H., Morse, Keith E., Brunskill, Emma P., Fries, Jason A., and Shah, Nigam H.
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on realistic text generation tasks for healthcare remains challenging. Existing question answering datasets for electronic health record (EHR) data fail to capture the complexity of information needs and documentation burdens experienced by clinicians. To address these challenges, we introduce MedAlign, a benchmark dataset of 983 natural language instructions for EHR data. MedAlign is curated by 15 clinicians (7 specialities), includes clinician-written reference responses for 303 instructions, and provides 276 longitudinal EHRs for grounding instruction-response pairs. We used MedAlign to evaluate 6 general domain LLMs, having clinicians rank the accuracy and quality of each LLM response. We found high error rates, ranging from 35% (GPT-4) to 68% (MPT-7B-Instruct), and an 8.3% drop in accuracy moving from 32k to 2k context lengths for GPT-4. Finally, we report correlations between clinician rankings and automated natural language generation metrics as a way to rank LLMs without human review. We make MedAlign available under a research data use agreement to enable LLM evaluations on tasks aligned with clinician needs and preferences.
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- 2023
4. Long-rising Type II Supernovae in the Zwicky Transient Facility Census of the Local Universe
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Sit, Tawny, Kasliwal, Mansi M., Tzanidakis, Anastasios, De, Kishalay, Fremling, Christoffer, Sollerman, Jesper, Gal-Yam, Avishay, Miller, Adam A., Adams, Scott, Aloisi, Robert, Andreoni, Igor, Chu, Matthew, Cook, David, Das, Kaustav Kashyap, Dugas, Alison, Groom, Steven L., Ho, Anna Y. Q., Karambelkar, Viraj, Neill, James D., Masci, Frank J., Medford, Michael S., Purdum, Josiah, Sharma, Yashvi, Smith, Roger, Stein, Robert, Yan, Lin, Yao, Yuhan, and Zhang, Chaoran
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
SN 1987A was an unusual hydrogen-rich core-collapse supernova originating from a blue supergiant star. Similar blue supergiant explosions remain a small family of events, and are broadly characterized by their long rises to peak. The Zwicky Transient Facility (ZTF) Census of the Local Universe (CLU) experiment aims to construct a spectroscopically complete sample of transients occurring in galaxies from the CLU galaxy catalog. We identify 13 long-rising (>40 days) Type II supernovae from the volume-limited CLU experiment during a 3.5 year period from June 2018 to December 2021, approximately doubling the previously known number of these events. We present photometric and spectroscopic data of these 13 events, finding peak r-band absolute magnitudes ranging from -15.6 to -17.5 mag and the tentative detection of Ba II lines in 9 events. Using our CLU sample of events, we derive a long-rising Type II supernova rate of $1.37^{+0.26}_{-0.30}\times10^{-6}$ Mpc$^{-3}$ yr$^{-1}$, $\approx$1.4% of the total core-collapse supernova rate. This is the first volumetric rate of these events estimated from a large, systematic, volume-limited experiment., Comment: 33 pages, 18 figures, 5 tables. Updated to ApJ accepted version
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- 2023
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5. Incorporating Exercise Training into Cardio-Oncology Care: Current Evidence and Opportunities: JACC: CardioOncology State-of-the-Art Review.
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Wilson, Rebekah L, Christopher, Cami N, Yang, Eric H, Barac, Ana, Adams, Scott C, Scott, Jessica M, and Dieli-Conwright, Christina M
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Cancer treatment-induced cardiotoxicities are an ongoing concern throughout the cancer care continuum from treatment initiation to survivorship. Several "standard-of-care" primary, secondary, and tertiary prevention strategies are available to prevent the development or further progression of cancer treatment-induced cardiotoxicities and their risk factors. Despite exercise's established benefits on the cardiovascular system, it has not been widely adopted as a nonpharmacologic cardioprotective strategy within cardio-oncology care. In this state-of-the-art review, the authors discuss cancer treatment-induced cardiotoxicities, review the existing evidence supporting the role of exercise in preventing and managing these sequelae in at-risk and affected individuals living after cancer diagnoses, and propose considerations for implementing exercise-based services in cardio-oncology practice.
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- 2023
6. Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration
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Morrison Margaux A, Silveira Alexandra C, Huynh Nancy, Jun Gyungah, Smith Silvia E, Zacharaki Fani, Sato Hajime, Loomis Stephanie, Andreoli Michael T, Adams Scott M, Radeke Monte J, Jelcick Austin S, Yuan Yang, Tsiloulis Aristoteles N, Chatzoulis Dimitrios Z, Silvestri Giuliana, Kotoula Maria G, Tsironi Evangelia E, Hollis Bruce W, Chen Rui, Haider Neena B, Miller Joan W, Farrer Lindsay A, Hageman Gregory S, Kim Ivana K, Schaumberg Debra A, and DeAngelis Margaret M
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vitamin D ,age-related macular degeneration ,Medicine ,Genetics ,QH426-470 - Abstract
Abstract Vitamin D has been shown to have anti-angiogenic properties and to play a protective role in several types of cancer, including breast, prostate and cutaneous melanoma. Similarly, vitamin D levels have been shown to be protective for risk of a number of conditions, including cardiovascular disease and chronic kidney disease, as well as numerous autoimmune disorders such as multiple sclerosis, inflammatory bowel diseases and type 1 diabetes mellitus. A study performed by Parekh et al. was the first to suggest a role for vitamin D in age-related macular degeneration (AMD) and showed a correlation between reduced serum vitamin D levels and risk for early AMD. Based on this study and the protective role of vitamin D in diseases with similar pathophysiology to AMD, we examined the role of vitamin D in a family-based cohort of 481 sibling pairs. Using extremely phenotypically discordant sibling pairs, initially we evaluated the association of neovascular AMD and vitamin D/sunlight-related epidemiological factors. After controlling for established AMD risk factors, including polymorphisms of the genes encoding complement factor H (CFH) and age-related maculopathy susceptibility 2/HtrA serine peptidase (ARMS2/HTRA1), and smoking history, we found that ultraviolet irradiance was protective for the development of neovascular AMD (p = 0.001). Although evaluation of serum vitamin D levels (25-hydroxyvitamin D [25(OH)D]) was higher in unaffected individuals than in their affected siblings, this finding did not reach statistical significance. Based on the relationship between ultraviolet irradiance and vitamin D production, we employed a candidate gene approach for evaluating common variation in key vitamin D pathway genes (the genes encoding the vitamin D receptor [VDR]; cytochrome P450, family 27, subfamily B, polypeptide 1 [CYP27B1]; cytochrome P450, family 24, subfamily A, polypeptide 1 [CYP24A1]; and CYP27A1) in this same family-based cohort. Initial findings were then validated and replicated in the extended family cohort, an unrelated case-control cohort from central Greece and a prospective nested case-control population from the Nurse's Health Study and Health Professionals Follow-Up Studies, which included patients with all subtypes of AMD for a total of 2,528 individuals. Single point variants in CYP24A1 (the gene encoding the catabolising enzyme of the vitamin D pathway) were demonstrated to influence AMD risk after controlling for smoking history, sex and age in all populations, both separately and, more importantly, in a meta-analysis. This is the first report demonstrating a genetic association between vitamin D metabolism and AMD risk. These findings were also supplemented with expression data from human donor eyes and human retinal cell lines. These data not only extend previous biological studies in the AMD field, but further emphasise common antecedents between several disorders with an inflammatory/immunogenic component such as cardiovascular disease, cancer and AMD.
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- 2011
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7. A Search for Extragalactic Fast Blue Optical Transients in ZTF and the Rate of AT2018cow-like Transients
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Ho, Anna YQ, Perley, Daniel A, Gal-Yam, Avishay, Lunnan, Ragnhild, Sollerman, Jesper, Schulze, Steve, Das, Kaustav K, Dobie, Dougal, Yao, Yuhan, Fremling, Christoffer, Adams, Scott, Anand, Shreya, Andreoni, Igor, Bellm, Eric C, Bruch, Rachel J, Burdge, Kevin B, Castro-Tirado, Alberto J, Dahiwale, Aishwarya, De, Kishalay, Dekany, Richard, Drake, Andrew J, Duev, Dmitry A, Graham, Matthew J, Helou, George, Kaplan, David L, Karambelkar, Viraj, Kasliwal, Mansi M, Kool, Erik C, Kulkarni, SR, Mahabal, Ashish A, Medford, Michael S, Miller, AA, Nordin, Jakob, Ofek, Eran, Petitpas, Glen, Riddle, Reed, Sharma, Yashvi, Smith, Roger, Stewart, Adam J, Taggart, Kirsty, Tartaglia, Leonardo, Tzanidakis, Anastasios, and Winters, Jan Martin
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Astronomical Sciences ,Physical Sciences ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) ,Astronomy & Astrophysics ,Astronomical sciences ,Particle and high energy physics ,Space sciences - Abstract
We present a search for extragalactic fast blue optical transients (FBOTs) during Phase I of the Zwicky Transient Facility (ZTF). We identify 38 candidates with durations above half-maximum light 1 day < t 1/2 < 12 days, of which 28 have blue (g − r ≲ −0.2 mag) colors at peak light. Of the 38 transients (28 FBOTs), 19 (13) can be spectroscopically classified as core-collapse supernovae (SNe): 11 (8) H- or He-rich (Type II/IIb/Ib) SNe, 6 (4) interacting (Type IIn/Ibn) SNe, and 2 (1) H&He-poor (Type Ic/Ic-BL) SNe. Two FBOTs (published previously) had predominantly featureless spectra and luminous radio emission: AT2018lug (The Koala) and AT2020xnd (The Camel). Seven (five) did not have a definitive classification: AT 2020bdh showed tentative broad Hα in emission, and AT 2020bot showed unidentified broad features and was 10 kpc offset from the center of an early-type galaxy. Ten (eight) have no spectroscopic observations or redshift measurements. We present multiwavelength (radio, millimeter, and/or X-ray) observations for five FBOTs (three Type Ibn, one Type IIn/Ibn, one Type IIb). Additionally, we search radio-survey (VLA and ASKAP) data to set limits on the presence of radio emission for 24 of the transients. All X-ray and radio observations resulted in nondetections; we rule out AT2018cow-like X-ray and radio behavior for five FBOTs and more luminous emission (such as that seen in the Camel) for four additional FBOTs. We conclude that exotic transients similar to AT2018cow, the Koala, and the Camel represent a rare subset of FBOTs and use ZTF’s SN classification experiments to measure the rate to be at most 0.1% of the local core-collapse SN rate.
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- 2023
8. Advancements in AI-Driven detection and localisation of solar panel defects
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Ghahremani, Ali, Adams, Scott D., Norton, Michael, Khoo, Sui Yang, and Kouzani, Abbas Z.
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- 2025
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9. Deep learning-based age estimation from chest CT scans
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Azarfar, Ghazal, Ko, Seok-Bum, Adams, Scott J., and Babyn, Paul S.
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- 2024
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10. Self-Supervised Leaf Segmentation under Complex Lighting Conditions
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Lin, Xufeng, Li, Chang-Tsun, Adams, Scott, Kouzani, Abbas, Jiang, Richard, He, Ligang, Hu, Yongjian, Vernon, Michael, Doeven, Egan, Webb, Lawrence, Mcclellan, Todd, and Guskic, Adam
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Computer Science - Computer Vision and Pattern Recognition ,Electrical Engineering and Systems Science - Image and Video Processing - Abstract
As an essential prerequisite task in image-based plant phenotyping, leaf segmentation has garnered increasing attention in recent years. While self-supervised learning is emerging as an effective alternative to various computer vision tasks, its adaptation for image-based plant phenotyping remains rather unexplored. In this work, we present a self-supervised leaf segmentation framework consisting of a self-supervised semantic segmentation model, a color-based leaf segmentation algorithm, and a self-supervised color correction model. The self-supervised semantic segmentation model groups the semantically similar pixels by iteratively referring to the self-contained information, allowing the pixels of the same semantic object to be jointly considered by the color-based leaf segmentation algorithm for identifying the leaf regions. Additionally, we propose to use a self-supervised color correction model for images taken under complex illumination conditions. Experimental results on datasets of different plant species demonstrate the potential of the proposed self-supervised framework in achieving effective and generalizable leaf segmentation.
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- 2022
11. Hubble Space Telescope Imaging of Luminous Extragalactic Infrared Transients and Variables from the SPIRITS Survey
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Bond, Howard E., Jencson, Jacob E., Whitelock, Patricia A., Adams, Scott M., Bally, John, Cody, Ann Marie, Gehrz, Robert D., Kasliwal, Mansi M., and Masci, Frank J.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
SPIRITS--the SPitzer InfraRed Intensive Transients Survey--searched for luminous infrared (IR) transients and variables in nearly 200 nearby galaxies from 2014 to 2019, using the warm Spitzer telescope at 3.6 and 4.5 microns. Among the SPIRITS variables are IR-bright objects that are undetected in ground-based optical surveys. We classify them as (1) transients, (2) periodic variables, and (3) irregular variables. The transients include "SPRITE"s (eSPecially Red Intermediate-luminosity Transient Events), having maximum luminosities fainter than supernovae, red IR colors, and a wide range of outburst durations (days to years). Here we report deep optical and near-IR imaging with the Hubble Space Telescope (HST) of 21 SPIRITS variables. They were initially considered SPRITE transients, but many eventually proved instead to be periodic or irregular variables as more data were collected. HST images show most of these cool and dusty variables are associated with star-forming regions in late-type galaxies, implying an origin in massive stars. Two SPRITEs lacked optical progenitors in deep pre-outburst HST images; however, one was detected during eruption at J and H, indicating a dusty object with an effective temperature of ~1050 K. One faint SPRITE turned out to be a dusty classical nova. About half the HST targets proved to be periodic variables, with pulsation periods of 670-2160 days; they are likely dusty asymptotic-giant-branch (AGB) stars with masses of ~5-10 Msun. A few of them were warm enough to be detected in deep HST frames, but most are too cool. Out of six irregular variables, two were red supergiants with optical counterparts in HST images; four were too enshrouded for HST detection., Comment: Accepted by Astrophysical Journal
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- 2022
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12. Mechanical processes for recycling of End-of-Life Tyres
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Pei, Yang, Han, Bing, Kumar, Dileep, Adams, Scott D., Khoo, Sui Yang, Norton, Michael, and Kouzani, Abbas Z.
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- 2024
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13. Large Language Models as Tools to Generate Radiology Board-Style Multiple-Choice Questions
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Mistry, Neel P., Saeed, Huzaifa, Rafique, Sidra, Le, Thuy, Obaid, Haron, and Adams, Scott J.
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- 2024
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14. Modelling of thermochemical processes of waste recycling: A review
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Han, Bing, Kumar, Dileep, Pei, Yang, Norton, Michael, Adams, Scott D., Khoo, Sui Yang, and Kouzani, Abbas Z.
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- 2024
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15. A self-stiffening compliant intracortical microprobe
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Sharafkhani, Naser, Long, John M., Adams, Scott D., and Kouzani, Abbas Z.
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- 2024
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16. Applications of deep learning to reduce the need for iodinated contrast media for CT imaging: a systematic review
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Azarfar, Ghazal, Ko, Seok-Bum, Adams, Scott J., and Babyn, Paul S.
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- 2023
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17. A Search for Extragalactic Fast Blue Optical Transients in ZTF and the Rate of AT2018cow-like Transients
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Ho, Anna Y. Q., Perley, Daniel A., Gal-Yam, Avishay, Lunnan, Ragnhild, Sollerman, Jesper, Schulze, Steve, Das, Kaustav K., Dobie, Dougal, Yao, Yuhan, Fremling, Christoffer, Adams, Scott, Anand, Shreya, Andreoni, Igor, Bellm, Eric C., Bruch, Rachel J., Burdge, Kevin B., Castro-Tirado, Alberto J., Dahiwale, Aishwarya, De, Kishalay, Dekany, Richard, Drake, Andrew J., Duev, Dmitry A., Graham, Matthew J., Helou, George, Kaplan, David L., Karambelkar, Viraj, Kasliwal, Mansi M., Kool, Erik C., Kulkarni, S. R., Mahabal, Ashish A., Medford, Michael S., Miller, A. A., Nordin, Jakob, Ofek, Eran, Petitpas, Glen, Riddle, Reed, Sharma, Yashvi, Smith, Roger, Stewart, Adam J., Taggart, Kirsty, Tartaglia, Leonardo, Tzanidakis, Anastasios, and Winters, Jan Martin
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present a search for extragalactic fast blue optical transients (FBOTs) during Phase I of the Zwicky Transient Facility (ZTF). We identify 38 candidates with durations above half-maximum light 1 d < t1/2 < 12 d, of which 28 have blue (g-r<-0.2 mag) colors at peak light. Of the 38 transients (28 FBOTs), 19 (13) can be spectroscopically classified as core-collapse supernovae (SNe): 11 (8) H- or He-rich (Type II/IIb/Ib) SNe, 6 (4) interacting (Type IIn/Ibn) SNe, and 2 (1) H&He-poor (Type Ic/Ic-BL) SNe. Two FBOTs (published previously) had high-S/N predominantly featureless spectra and luminous radio emission: AT2018lug and AT2020xnd. Seven (five) did not have a definitive classification: AT 2020bdh showed tentative broad H$\alpha$ in emission, and AT 2020bot showed unidentified broad features and was 10 kpc offset from the center of an early-type galaxy. Ten (six) have no spectroscopic observations or redshift measurements. We present multiwavelength (radio, millimeter, and/or X-ray) observations for five FBOTs (three Type Ibn, one Type IIn/Ibn, one Type IIb). Additionally, we search radio-survey (VLA and ASKAP) data to set limits on the presence of radio emission for 22 of the transients. All X-ray and radio observations resulted in non-detections; we rule out AT2018cow-like X-ray and radio behavior for five FBOTs and more luminous emission (such as that seen in the Camel) for four additional FBOTs. We conclude that exotic transients similar to AT2018cow, the Koala, and the Camel represent a rare subset of FBOTs, and use ZTF's SN classification experiments to measure the rate to be at most 0.1% of the local core-collapse SN rate., Comment: Replaced following peer-review process. 46 pages, 20 figures. Accepted for publication in ApJ
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- 2021
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18. Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy
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Uldrick, Thomas S, Adams, Scott V, Fromentin, Remi, Roche, Michael, Fling, Steven P, Gonçalves, Priscila H, Lurain, Kathryn, Ramaswami, Ramya, Wang, Chia-Ching Jackie, Gorelick, Robert J, Welker, Jorden L, O'Donoghue, Liz, Choudhary, Harleen, Lifson, Jeffrey D, Rasmussen, Thomas A, Rhodes, Ajantha, Tumpach, Carolin, Yarchoan, Robert, Maldarelli, Frank, Cheever, Martin A, Sékaly, Rafick, Chomont, Nicolas, Deeks, Steven G, and Lewin, Sharon R
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Medical Microbiology ,Biomedical and Clinical Sciences ,Immunology ,Infectious Diseases ,Genetics ,Cancer ,HIV/AIDS ,2.2 Factors relating to the physical environment ,Aetiology ,Infection ,Antibodies ,Monoclonal ,Humanized ,CD4-Positive T-Lymphocytes ,HIV Infections ,HIV-1 ,Humans ,Neoplasms ,Phylogeny ,Programmed Cell Death 1 Receptor ,RNA ,Virus Latency ,Biological Sciences ,Medical and Health Sciences ,Medical biotechnology ,Biomedical engineering - Abstract
In people living with HIV (PLWH) on antiretroviral therapy (ART), virus persists in a latent form where there is minimal transcription or protein expression. Latently infected cells are a major barrier to curing HIV. Increasing HIV transcription and viral production in latently infected cells could facilitate immune recognition and reduce the pool of infected cells that persist on ART. Given that programmed cell death protein 1 (PD-1) expressing CD4+ T cells are preferentially infected with HIV in PLWH on ART, we aimed to determine whether administration of antibodies targeting PD-1 would reverse HIV latency in vivo. We therefore evaluated the impact of intravenous administration of pembrolizumab every 3 weeks on HIV latency in 32 PLWH and cancer on ART. After the first infusion of anti-PD-1, we observed a median 1.32-fold increase in unspliced HIV RNA and 1.61-fold increase in unspliced RNA:DNA ratio in sorted blood CD4+ T cells compared to baseline. We also observed a 1.65-fold increase in plasma HIV RNA. The frequency of CD4+ T cells with inducible virus evaluated using the tat/rev limiting dilution assay was higher after 6 cycles compared to baseline. Phylogenetic analyses of HIV env sequences in a participant who developed low concentrations of HIV viremia after 6 cycles of pembrolizumab did not demonstrate clonal expansion of HIV-infected cells. These data are consistent with anti-PD-1 being able to reverse HIV latency in vivo and support the rationale for combining anti-PD-1 with other interventions to reduce the HIV reservoir.
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- 2022
19. Comparative Effectiveness of Dialysis Modality on Laboratory Parameters of Mineral Metabolism
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Soohoo, Melissa, Obi, Yoshitsugu, Rivara, Matthew B, Adams, Scott V, Lau, Wei Ling, Rhee, Connie M, Kovesdy, Csaba P, Kalantar-Zadeh, Kamyar, Arah, Onyebuchi A, Mehrotra, Rajnish, and Streja, Elani
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Biomedical and Clinical Sciences ,Clinical Sciences ,Bioengineering ,Kidney Disease ,Assistive Technology ,Clinical Research ,Women's Health ,Renal and urogenital ,Calcium ,Chronic Kidney Disease-Mineral and Bone Disorder ,Cohort Studies ,Humans ,Minerals ,Parathyroid Hormone ,Renal Dialysis ,Maintenance dialysis ,Mineral and bone disorders ,Marginal structural model ,In-center hemodialysis ,Peritoneal dialysis ,Extended-hours hemodialysis ,Nocturnal hemodialysis ,Urology & Nephrology ,Clinical sciences - Abstract
IntroductionChronic kidney disease-mineral and bone disorders (CKD-MBD) are prevalent in patients undergoing maintenance dialysis. Yet, there are limited and mixed evidence on the effects of different dialysis modalities involving longer treatment times or higher frequencies on CKD-MBD markers.MethodsThis cohort study used data from 132,523 incident dialysis patients treated with any of the following modalities: conventional thrice-weekly in-center hemodialysis, nocturnal in-center hemodialysis (NICHD), home hemodialysis (HHD), or peritoneal dialysis (PD) from 2007 to 2011. We used marginal structural models fitted with inverse probability weights to adjust for fixed and time-varying confounding and informative censoring. We estimated the average effects of treatments with different dialysis modalities on time-varying serum concentrations of CKD-MBD markers: albumin-corrected calcium, phosphate, parathyroid hormone (PTH), and alkaline phosphatase (ALP) using pooled linear regression.ResultsMost of the cohort were exclusively treated with conventional in-center hemodialysis, while few were ever treated with NICHD or HHD. At the baseline, PD patients had the lowest mean and median values of PTH, while NICHD patients had the highest median values. During follow-up, compared to hemodialysis patients, patients treated with NICHD had lower mean serum PTH (19.8 pg/mL [95% confidence interval: 2.8, 36.8] lower), whereas PD and HHD patients had higher mean PTH (39.7 pg/mL [31.6, 47.8] and 51.2 pg/mL [33.0, 69.3] higher, respectively). Compared to hemodialysis patients, phosphate levels were lower for patients treated with NICHD (0.44 mg/dL [0.37, 0.52] lower), PD (0.15 mg/dL [0.12, 0.19] lower), or HHD (0.33 mg/dL [0.27, 0.40] lower). There were no clinically meaningful associations between dialysis modalities and concentrations of calcium or ALP.ConclusionIn incident dialysis patients, compared to treatment with conventional in-center hemodialysis, treatments with other dialysis modalities with longer treatment times or higher frequency were associated with different patterns of serum phosphate and PTH. Given the recent growth in the use of dialysis modalities other than hemodialysis, the associations between the treatment and the CKD-MBD markers warrant additional study.
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- 2022
20. The STRAT-PARK cohort: A personalized initiative to stratify Parkinson’s disease
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Stige, Kjersti Eline, Kverneng, Simon Ulvenes, Sharma, Soumya, Skeie, Geir-Olve, Sheard, Erika, Søgnen, Mona, Geijerstam, Solveig Af, Vetås, Therese, Wahlvåg, Anne Grete, Berven, Haakon, Buch, Sagar, Reese, David, Babiker, Dina, Mahdi, Yekta, Wade, Trevor, Miranda, Gala Prado, Ganguly, Jacky, Tamilselvam, Yokhesh Krishnasamy, Chai, Jia Ren, Bansal, Saurabh, Aur, Dorian, Soltani, Sima, Adams, Scott, Dölle, Christian, Dick, Fiona, Berntsen, Erik Magnus, Grüner, Renate, Brekke, Njål, Riemer, Frank, Goa, Pål Erik, Haugarvoll, Kristoffer, Haacke, E. Mark, Jog, Mandar, and Tzoulis, Charalampos
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- 2024
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21. A 3D printed intracortical microprobe with automatic effective stiffness control
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Sharafkhani, Naser, Long, John M., Adams, Scott D., and Kouzani, Abbas Z.
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- 2024
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22. Volumetric additive manufacturing: A new frontier in layer-less 3D printing
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Whyte, Daniel J., Doeven, Egan H., Sutti, Alessandra, Kouzani, Abbas Z., and Adams, Scott D.
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- 2024
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23. A population of heavily reddened, optically missed novae from Palomar Gattini-IR: Constraints on the Galactic nova rate
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De, Kishalay, Kasliwal, Mansi M., Hankins, Matthew J., Sokoloski, Jennifer L., Adams, Scott M., Ashley, Michael C. B., Babul, Aliya-Nur, Bagdasaryan, Ashot, Delacroix, Alexandre, Dekany, Richard, Greffe, Timothee, Hale, David, Jencson, Jacob E., Karambelkar, Viraj R., Lau, Ryan M., Mahabal, Ashish, McKenna, Daniel, Moore, Anna M., Ofek, Eran O., Sharma, Manasi, Smith, Roger M., Soon, Jamie, Soria, Roberto, Srinivasaragavan, Gokul, Tinyanont, Samaporn, Travouillon, Tony, Tzanidakis, Anastasios, and Yao, Yuhan
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The nova rate in the Milky Way remains largely uncertain, despite its vital importance in constraining models of Galactic chemical evolution as well as understanding progenitor channels for Type Ia supernovae. The rate has been previously estimated in the range of $\approx10-300$ yr$^{-1}$, either based on extrapolations from a handful of very bright optical novae or the nova rates in nearby galaxies; both methods are subject to debatable assumptions. The total discovery rate of optical novae remains much smaller ($\approx5-10$ yr$^{-1}$) than these estimates, even with the advent of all-sky optical time domain surveys. Here, we present a systematic sample of 12 spectroscopically confirmed Galactic novae detected in the first 17 months of Palomar Gattini-IR (PGIR), a wide-field near-infrared time domain survey. Operating in $J$-band ($\approx1.2$ $\mu$m) that is relatively immune to dust extinction, the extinction distribution of the PGIR sample is highly skewed to large extinction values ($> 50$% of events obscured by $A_V\gtrsim5$ mag). Using recent estimates for the distribution of mass and dust in the Galaxy, we show that the observed extinction distribution of the PGIR sample is commensurate with that expected from dust models. The PGIR extinction distribution is inconsistent with that reported in previous optical searches (null hypothesis probability $< 0.01$%), suggesting that a large population of highly obscured novae have been systematically missed in previous optical searches. We perform the first quantitative simulation of a $3\pi$ time domain survey to estimate the Galactic nova rate using PGIR, and derive a rate of $\approx 46.0^{+12.5}_{-12.4}$ yr$^{-1}$. Our results suggest that all-sky near-infrared time-domain surveys are well poised to uncover the Galactic nova population., Comment: 25 pages, 12 figures. Submitted to ApJ
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- 2021
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24. Automatic classification of multiple catheters in neonatal radiographs with deep learning
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Henderson, Robert D. E., Yi, Xin, Adams, Scott J., and Babyn, Paul
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Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
We develop and evaluate a deep learning algorithm to classify multiple catheters on neonatal chest and abdominal radiographs. A convolutional neural network (CNN) was trained using a dataset of 777 neonatal chest and abdominal radiographs, with a split of 81%-9%-10% for training-validation-testing, respectively. We employed ResNet-50 (a CNN), pre-trained on ImageNet. Ground truth labelling was limited to tagging each image to indicate the presence or absence of endotracheal tubes (ETTs), nasogastric tubes (NGTs), and umbilical arterial and venous catheters (UACs, UVCs). The data set included 561 images containing 2 or more catheters, 167 images with only one, and 49 with none. Performance was measured with average precision (AP), calculated from the area under the precision-recall curve. On our test data, the algorithm achieved an overall AP (95% confidence interval) of 0.977 (0.679-0.999) for NGTs, 0.989 (0.751-1.000) for ETTs, 0.979 (0.873-0.997) for UACs, and 0.937 (0.785-0.984) for UVCs. Performance was similar for the set of 58 test images consisting of 2 or more catheters, with an AP of 0.975 (0.255-1.000) for NGTs, 0.997 (0.009-1.000) for ETTs, 0.981 (0.797-0.998) for UACs, and 0.937 (0.689-0.990) for UVCs. Our network thus achieves strong performance in the simultaneous detection of these four catheter types. Radiologists may use such an algorithm as a time-saving mechanism to automate reporting of catheters on radiographs., Comment: 10 pages, 5 figures (+1 suppl.), 2 tables (+2 suppl.). Submitted to Journal of Digital Imaging
- Published
- 2020
25. Bright, months-long stellar outbursts announce the explosion of interaction-powered supernovae
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Strotjohann, Nora L., Ofek, Eran O., Gal-Yam, Avishay, Bruch, Rachel, Schulze, Steve, Shaviv, Nir, Sollerman, Jesper, Filippenko, Alexei V., Yaron, Ofer, Fremling, Christoffer, Nordin, Jakob, Kool, Erik C., Perley, Dan A., Ho, Anna Y. Q., Yang, Yi, Yao, Yuhan, Soumagnac, Maayane T., Graham, Melissa L., Barbarino, Cristina, Tartaglia, Leonardo, De, Kishalay, Goldstein, Daniel A., Cook, David O., Brink, Thomas G., Taggart, Kirsty, Yan, Lin, Lunnan, Ragnhild, Kasliwal, Mansi, Kulkarni, Shri R., Nugent, Peter E., Masci, Frank J., Rosnet, Philippe, Adams, Scott M., Andreoni, Igor, Bagdasaryan, Ashot, Bellm, Eric C., Burdge, Kevin, Duev, Dmitry A., Dugas, Alison, Frederick, Sara, Goldwasser, Samantha, Hankins, Matthew, Irani, Ido, Karambelkar, Viraj, Kupfer, Thomas, Liang, Jingyi, Neill, James D., Porter, Michael, Riddle, Reed L., Sharma, Yashvi, Short, Phil, Taddia, Francesco, Tzanidakis, Anastasios, van Roestel, Jan, Walters, Richard, and Zhuang, Zhuyun
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
Interaction-powered supernovae (SNe) explode within an optically-thick circumstellar medium (CSM) that could be ejected during eruptive events. To identify and characterize such pre-explosion outbursts we produce forced-photometry light curves for 196 interacting SNe, mostly of Type IIn, detected by the Zwicky Transient Facility between early 2018 and June 2020. Extensive tests demonstrate that we only expect a few false detections among the 70,000 analyzed pre-explosion images after applying quality cuts and bias corrections. We detect precursor eruptions prior to 18 Type IIn SNe and prior to the Type Ibn SN2019uo. Precursors become brighter and more frequent in the last months before the SN and month-long outbursts brighter than magnitude -13 occur prior to 25% (5 - 69%, 95% confidence range) of all Type IIn SNe within the final three months before the explosion. With radiative energies of up to $10^{49}\,\text{erg}$, precursors could eject $\sim1\,\text{M}_\odot$ of material. Nevertheless, SNe with detected precursors are not significantly more luminous than other SNe IIn and the characteristic narrow hydrogen lines in their spectra typically originate from earlier, undetected mass-loss events. The long precursor durations require ongoing energy injection and they could, for example, be powered by interaction or by a continuum-driven wind. Instabilities during the neon and oxygen burning phases are predicted to launch precursors in the final years to months before the explosion; however, the brightest precursor is 100 times more energetic than anticipated.
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- 2020
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26. The Palomar Transient Factory Core-Collapse Supernova Host-Galaxy Sample. I. Host-Galaxy Distribution Functions and Environment-Dependence of CCSNe
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Schulze, Steve, Yaron, Ofer, Sollerman, Jesper, Leloudas, Giorgos, Gal, Amit, Wright, Angus H., Lunnan, Ragnhild, Gal-Yam, Avishay, Ofek, Eran O., Perley, Daniel A., Filippenko, Alexei V., Kasliwal, Mansi M., Kulkarni, Shri R., Nugent, Peter E., Quimby, Robert M., Sullivan, Mark, Strothjohann, Nora Linn, Arcavi, Iair, Ben-Ami, Sagi, Bianco, Federica, Bloom, Joshua S., De, Kishalay, Fraser, Morgan, Fremling, Christoffer U., Horesh, Assaf, Johansson, Joel, Kelly, Patrick L., Knezevic, Sladjana, Maguire, Kate, Nyholm, Anders, Papadogiannakis, 2 Semeli, Petrushevska, Tanja, Rubin, Adam, Yan, Lin, Yang, Yi, Adams, Scott M., Bufano, Filomena, Clubb, Kelsey I., Foley, Ryan J., Green, Yoav, Harmanen, Jussi, Ho, Anna Y. Q., Hook, Isobel M., Hosseinzadeh, Griffin, Howell, D. Andrew, Kong, Albert K. H., Kotak, Rubina, Matheson, Thomas, McCully, Curtis, Milisavljevic, Dan, Pan, Yen-Chen, Poznanski, Dovi, Shivvers, Isaac, and van Velzen, Sjoert
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
Several thousand core-collapse supernovae (CCSNe) of different flavors have been discovered so far. However, identifying their progenitors has remained an outstanding open question in astrophysics. Studies of SN host galaxies have proven to be powerful in providing constraints on the progenitor populations. In this paper, we present all CCSNe detected between 2009 and 2017 by the Palomar Transient Factory. This sample includes 888 SNe of 12 distinct classes out to redshift $z\approx1$. We present the photometric properties of their host galaxies from the far-ultraviolet to the mid-infrared and model the host-galaxy spectral energy distributions to derive physical properties. The galaxy mass functions of Type Ic, Ib, IIb, II, and IIn SNe ranges from $10^{5}$ to $10^{11.5}~M_\odot$, probing the entire mass range of star-forming galaxies down to the least-massive star-forming galaxies known. Moreover, the galaxy mass distributions are consistent with models of star-formation-weighted mass functions. Regular CCSNe are hence direct tracers of star formation. Small but notable differences exist between some of the SN classes. Type Ib/c SNe prefer galaxies with slightly higher masses (i.e., higher metallicities) and star-formation rates than Type IIb and II SNe. These differences are less pronounced than previously thought. H-poor SLSNe and SNe~Ic-BL are scarce in galaxies above $10^{10}~M_\odot$. Their progenitors require environments with metallicities of $<0.4$ and $<1$ solar, respectively. In addition, the hosts of H-poor SLSNe are dominated by a younger stellar population than all other classes of CCSNe. Our findings corroborate the notion that low-metallicity \textit{and} young age play an important role in the formation of SLSN progenitors., Comment: 24 pages main text, 14 figures, 9 Tables, catalogue available at http://www.github.com/steveschulze/PTF
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- 2020
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27. The Zwicky Transient Facility Census of the Local Universe I: Systematic search for Calcium rich gap transients reveal three related spectroscopic sub-classes
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De, Kishalay, Kasliwal, Mansi M., Tzanidakis, Anastasios, Fremling, U. Christoffer, Adams, Scott, Andreoni, Igor, Bagdasaryan, Ashot, Bellm, Eric C., Bildsten, Lars, Cannella, Christopher, Cook, David O., Delacroix, Alexandre, Drake, Andrew, Duev, Dmitry, Dugas, Alison, Frederick, Sara, Gal-Yam, Avishay, Goldstein, Daniel, Golkhou, V. Zach, Graham, Matthew J., Hale, David, Hankins, Matthew, Helou, George, Ho, Anna Y. Q., Irani, Ido, Jencson, Jacob E., Kaye, Stephen, Kulkarni, S. R., Kupfer, Thomas, Laher, Russ R., Leadbeater, Robin, Lunnan, Ragnhild, Masci, Frank J., Miller, Adam A., Neill, James D., Ofek, Eran O., Perley, Daniel A., Polin, Abigail, Prince, Thomas A., Quataert, Eliot, Reiley, Dan, Riddle, Reed L., Rusholme, Ben, Sharma, Yashvi, Shupe, David L., Sollerman, Jesper, Tartaglia, Leonardo, Walters, Richard, Yan, Lin, and Yao, Yuhan
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
(Abridged) Using the Zwicky Transient Facility alert stream, we are conducting a large campaign to spectroscopically classify all transients occurring in galaxies in the Census of the Local Universe (CLU) catalog. The aim of the experiment is to construct a spectroscopically complete, volume-limited sample of transients coincident within 100" of CLU galaxies out to 200 Mpc, and to a depth of 20 mag. We describe the survey design and spectroscopic completeness from the first 16 months of operations. We present results from a systematic search for Calcium rich gap transients in the sample of 22 low luminosity (peak absolute magnitude $M > -17$), hydrogen poor events found in the experiment (out of 754 spectroscopically classified SNe). We report the detection of eight Calcium rich gap transients, and constrain their volumetric rate to be at least $\approx 15\pm5$% of the SN Ia rate. Combining this sample with ten events from the literature, we find a likely continuum of spectroscopic properties ranging from events with SN Ia-like features (Ca-Ia objects) to SN Ib/c-like features (Ca-Ib/c objects) at peak light. Within the Ca-Ib/c events, we find two populations of events distinguished by their red ($g - r \approx 1.5$ mag) or green ($g - r \approx 0.5$ mag) spectral colors at $r$-band peak, wherein redder events show strong line blanketing signatures, slower light curves, weaker He lines and lower [Ca II]/[O I] in the nebular phase. Together, we find that the spectroscopic continuum, volumetric rates and striking old environments are consistent with the explosive burning of He shells on low mass white dwarfs. We posit that Ca-Ia and red Ca-Ib/c objects are consistent with the double detonation of He shells with high He burning efficiency, while green Ca-Ib/c objects could arise from less efficient He burning scenarios such as detonations in low density He shells or He shell deflagrations., Comment: 30 figures, 6 tables. Submitted to ApJ
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- 2020
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28. Progenitor, Precursor and Evolution of the Dusty Remnant of the Stellar Merger M31-LRN-2015
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Blagorodnova, Nadejda, Karambelkar, Viraj, Adams, Scott M., Kasliwal, Mansi M., Kochanek, Christopher S., Dong, Subo, Campbell, Heather, Hodgkin, Simon, Jencson, Jacob E., Johansson, Joel, Kozlowski, Szymon, Laher, Russ R., Masci, Frank, Nugent, Peter, and Rebbapragada, Umaa D.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
M31-2015-LRN is a likely stellar merger discovered in the Andromeda Galaxy in 2015. We present new optical to mid-infrared photometry and optical spectroscopy for this event. Archival data shows that the source started to brighten $\sim$2 years before the nova event. During this precursor phase, the source brightened by $\sim$3 mag. The lightcurve at 6 and 1.5 months before the main outburst may show periodicity, with periods of 16$\pm$0.3 and 28.1$\pm$1.4 days respectively. This complex emission may be explained by runaway mass loss from the system after the binary undergoes Roche-lobe overflow, leading the system to coalesce in tens of orbital periods. While the progenitor spectral energy distribution shows no evidence of pre-existing warm dust in system, the remnant forms an optically thick dust shell at $\sim$4 months after the outburst peak. The optical depth of the shell increases dramatically after 1.5 years, suggesting the existence of shocks that enhance the dust formation process. We propose that the merger remnant is likely an inflated giant obscured by a cooling shell of gas with mass $\sim0.2$ M$_{\odot}$ ejected at the onset of the common envelope phase., Comment: 16 pages, 10 figures. Accepted for publication in MNRAS
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- 2020
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29. The Palomar Transient Factory Core-collapse Supernova Host-galaxy Sample. I. Host-galaxy Distribution Functions and Environment Dependence of Core-collapse Supernovae
- Author
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Schulze, Steve, Yaron, Ofer, Sollerman, Jesper, Leloudas, Giorgos, Gal, Amit, Wright, Angus H, Lunnan, Ragnhild, Gal-Yam, Avishay, Ofek, Eran O, Perley, Daniel A, Filippenko, Alexei V, Kasliwal, Mansi M, Kulkarni, Shrinivas R, Neill, James D, Nugent, Peter E, Quimby, Robert M, Sullivan, Mark, Strotjohann, Nora Linn, Arcavi, Iair, Ben-Ami, Sagi, Bianco, Federica, Bloom, Joshua S, De, Kishalay, Fraser, Morgan, Fremling, Christoffer U, Horesh, Assaf, Johansson, Joel, Kelly, Patrick L, Knežević, Nikola, Knežević, Sladjana, Maguire, Kate, Nyholm, Anders, Papadogiannakis, Seméli, Petrushevska, Tanja, Rubin, Adam, Yan, Lin, Yang, Yi, Adams, Scott M, Bufano, Filomena, Clubb, Kelsey I, Foley, Ryan J, Green, Yoav, Harmanen, Jussi, Ho, Anna YQ, Hook, Isobel M, Hosseinzadeh, Griffin, Howell, D Andrew, Kong, Albert KH, Kotak, Rubina, Matheson, Thomas, McCully, Curtis, Milisavljevic, Dan, Pan, Yen-Chen, Poznanski, Dovi, Shivvers, Isaac, van Velzen, Sjoert, and Verbeek, Kars K
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Nuclear and Plasma Physics ,Physical Sciences ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) ,Astronomy & Astrophysics ,Astronomical sciences - Abstract
Several thousand core-collapse supernovae (CCSNe) of different flavors have been discovered so far. However, identifying their progenitors has remained an outstanding open question in astrophysics. Studies of SN host galaxies have proven to be powerful in providing constraints on the progenitor populations. In this paper, we present all CCSNe detected between 2009 and 2017 by the Palomar Transient Factory. This sample includes 888 SNe of 12 distinct classes out to redshift z ≈ 1. We present the photometric properties of their host galaxies from the far-ultraviolet to the mid-infrared and model the host-galaxy spectral energy distributions to derive physical properties. The galaxy mass function of Type Ic, Ib, IIb, II, and IIn SNe ranges from 105 to 1011.5 M o˙, probing the entire mass range of star-forming galaxies down to the least-massive star-forming galaxies known. Moreover, the galaxy mass distributions are consistent with models of star-formation-weighted mass functions. Regular CCSNe are hence direct tracers of star formation. Small but notable differences exist between some of the SN classes. Type Ib/c SNe prefer galaxies with slightly higher masses (i.e., higher metallicities) and star formation rates than Type IIb and II SNe. These differences are less pronounced than previously thought. H-poor superluminous supernovae (SLSNe) and SNe Ic-BL are scarce in galaxies above 1010 M o˙. Their progenitors require environments with metallicities of < 0.4 and < 1 solar, respectively. In addition, the hosts of H-poor SLSNe are dominated by a younger stellar population than all other classes of CCSNe. Our findings corroborate the notion that low metallicity and young age play an important role in the formation of SLSN progenitors.
- Published
- 2021
30. A binary stiffness compliant neural microprobe
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Sharafkhani, Naser, Long, John M., Adams, Scott D., and Kouzani, Abbas Z.
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- 2023
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31. The NEI/NCBI dbGAP database: Genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration
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Miller Joan W, Brown Alison, Regan Maureen, Huynh Nancy, Andreoli Michael, Adams Scott, DeWan Andy, Morrison Margaux A, Zhang Hong, Kim Ivana K, Hoh Josephine, and DeAngelis Margaret M
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Internal medicine ,RC31-1245 ,Genetics ,QH426-470 - Abstract
Abstract Background To examine if the significantly associated SNPs derived from the genome wide allelic association study on the AREDS cohort at the NEI (dbGAP) specifically confer risk for neovascular age-related macular degeneration (AMD). We ascertained 134 unrelated patients with AMD who had one sibling with an AREDS classification 1 or less and was past the age at which the affected sibling was diagnosed (268 subjects). Genotyping was performed by both direct sequencing and Sequenom iPLEX system technology. Single SNP analyses were conducted with McNemar's Test (both 2 × 2 and 3 × 3 tests) and likelihood ratio tests (LRT). Conditional logistic regression was used to determine significant gene-gene interactions. LRT was used to determine the best fit for each genotypic model tested (additive, dominant or recessive). Results Before release of individual data, p-value information was obtained directly from the AREDS dbGAP website. Of the 35 variants with P < 10-6 examined, 23 significantly modified risk of neovascular AMD. Many variants located in tandem on 1q32-q22 including those in CFH, CFHR4, CFHR2, CFHR5, F13B, ASPM and ZBTB were significantly associated with AMD risk. Of these variants, single SNP analysis revealed that CFH rs572515 was the most significantly associated with AMD risk (P < 10-6). Haplotype analysis supported our findings of single SNP association, demonstrating that the most significant haplotype, GATAGTTCTC, spanning CFH, CFHR4, and CFHR2 was associated with the greatest risk of developing neovascular AMD (P < 10-6). Other than variants on 1q32-q22, only two SNPs, rs9288410 (MAP2) on 2q34-q35 and rs2014307 (PLEKHA1/HTRA1) on 10q26 were significantly associated with AMD status (P = .03 and P < 10-6 respectively). After controlling for smoking history, gender and age, the most significant gene-gene interaction appears to be between rs10801575 (CFH) and rs2014307 (PLEKHA1/HTRA1) (P < 10-11). The best genotypic fit for rs10801575 and rs2014307 was an additive model based on LRT. After applying a Bonferonni correction, no other significant interactions were identified between any other SNPs. Conclusion This is the first replication study on the NEI dbGAP SNPs, demonstrating that alleles on 1q, 2q and 10q may predispose an individual to AMD.
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- 2008
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32. A pictorial review of the radiographic skeletal findings in Morquio syndrome (mucopolysaccharidosis type IV)
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Padash, Sirwa, Obaid, Haron, Henderson, Robert D. E., Padash, Yaseen, Adams, Scott J., Miller, Stephen F., and Babyn, Paul
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- 2023
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33. Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation
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Chen, Da-Yuan, Chin, Chue Vin, Kenney, Devin, Tavares, Alexander H., Khan, Nazimuddin, Conway, Hasahn L., Liu, GuanQun, Choudhary, Manish C., Gertje, Hans P., O’Connell, Aoife K., Adams, Scott, Kotton, Darrell N., Herrmann, Alexandra, Ensser, Armin, Connor, John H., Bosmann, Markus, Li, Jonathan Z., Gack, Michaela U., Baker, Susan C., Kirchdoerfer, Robert N., Kataria, Yachana, Crossland, Nicholas A., Douam, Florian, and Saeed, Mohsan
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- 2023
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34. Computer-Aided Assessment of Catheters and Tubes on Radiographs: How Good is Artificial Intelligence for Assessment?
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Yi, Xin, Adams, Scott J., Henderson, Robert D. E., and Babyn, Paul
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Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Machine Learning ,Physics - Medical Physics - Abstract
Catheters are the second most common abnormal finding on radiographs. The position of catheters must be assessed on all radiographs, as serious complications can arise if catheters are malpositioned. However, due to the large number of radiographs performed each day, there can be substantial delays between the time a radiograph is performed and when it is interpreted by a radiologist. Computer-aided approaches hold the potential to assist in prioritizing radiographs with potentially malpositioned catheters for interpretation and automatically insert text indicating the placement of catheters in radiology reports, thereby improving radiologists' efficiency. After 50 years of research in computer-aided diagnosis, there is still a paucity of study in this area. With the development of deep learning approaches, the problem of catheter assessment is far more solvable. Therefore, we have performed a review of current algorithms and identified key challenges in building a reliable computer-aided diagnosis system for assessment of catheters on radiographs. This review may serve to further the development of machine learning approaches for this important use case., Comment: This manuscript has been accepted for publication in Radiology: Artificial Intelligence (https://pubs.rsna.org/journal/ai), which is published by the Radiological Society of North America (RSNA)
- Published
- 2020
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35. Artificial Intelligence and Machine Learning in Lung Cancer Screening
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Adams, Scott J., Mikhael, Peter, Wohlwend, Jeremy, Barzilay, Regina, Sequist, Lecia V., and Fintelmann, Florian J.
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- 2023
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36. Bright, Months-long Stellar Outbursts Announce the Explosion of Interaction-powered Supernovae
- Author
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Strotjohann, Nora L, Ofek, Eran O, Gal-Yam, Avishay, Bruch, Rachel, Schulze, Steve, Shaviv, Nir, Sollerman, Jesper, Filippenko, Alexei V, Yaron, Ofer, Fremling, Christoffer, Nordin, Jakob, Kool, Erik C, Perley, Dan A, Ho, Anna YQ, Yang, Yi, Yao, Yuhan, Soumagnac, Maayane T, Graham, Melissa L, Barbarino, Cristina, Tartaglia, Leonardo, De, Kishalay, Goldstein, Daniel A, Cook, David O, Brink, Thomas G, Taggart, Kirsty, Yan, Lin, Lunnan, Ragnhild, Kasliwal, Mansi, Kulkarni, Shri R, Nugent, Peter E, Masci, Frank J, Rosnet, Philippe, Adams, Scott M, Andreoni, Igor, Bagdasaryan, Ashot, Bellm, Eric C, Burdge, Kevin, Duev, Dmitry A, Dugas, Alison, Frederick, Sara, Goldwasser, Samantha, Hankins, Matthew, Irani, Ido, Karambelkar, Viraj, Kupfer, Thomas, Liang, Jingyi, Neill, James D, Porter, Michael, Riddle, Reed L, Sharma, Yashvi, Short, Phil, Taddia, Francesco, Tzanidakis, Anastasios, van Roestel, Jan, Walters, Richard, and Zhuang, Zhuyun
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Eruptive phenomena ,Stellar mass loss ,Circumstellar matter ,Late stellar evolution ,Stellar flares ,Core-collapse supernovae ,astro-ph.HE ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) ,Astronomy & Astrophysics - Abstract
Interaction-powered supernovae (SNe) explode within an optically thick circumstellar medium (CSM) that could be ejected during eruptive events. To identify and characterize such pre-explosion outbursts, we produce forcedphotometry light curves for 196 interacting SNe, mostly of Type IIn, detected by the Zwicky Transient Facility between early 2018 and 2020 June. Extensive tests demonstrate that we only expect a few false detections among the 70,000 analyzed pre-explosion images after applying quality cuts and bias corrections. We detect precursor eruptions prior to 18 Type IIn SNe and prior to the Type Ibn SN 2019uo. Precursors become brighter and more frequent in the last months before the SN and month-long outbursts brighter than magnitude -13 occur prior to 25% (5-69%, 95% confidence range) of all Type IIn SNe within the final three months before the explosion. With radiative energies of up to 1049erg, precursors could eject ~1M⊙of material. Nevertheless, SNe with detected precursors are not significantly more luminous than other SNe IIn, and the characteristic narrow hydrogen lines in their spectra typically originate from earlier, undetected mass-loss events. The long precursor durations require ongoing energy injection, and they could, for example, be powered by interaction or by a continuum-driven wind. Instabilities during the neon- and oxygen-burning phases are predicted to launch precursors in the final years to months before the explosion; however, the brightest precursor is 100 times more energetic than anticipated.
- Published
- 2021
37. Design and methods of a randomized trial testing "Advancing care for COPD in people living with HIV by implementing evidence-based management through proactive E-consults (ACHIEVE)"
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Ives, Jennifer, Bagchi, Subarna, Soo, Sherilynn, Barrow, Cera, Akgün, Kathleen M., Erlandson, Kristine M., Goetz, Matthew, Griffith, Matthew, Gross, Robert, Hulgan, Todd, Moanna, Abeer, Soo Hoo, Guy W., Weintrob, Amy, Wongtrakool, Cherry, Adams, Scott V., Sayre, George, Helfrich, Christian D., Au, David H., and Crothers, Kristina
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- 2023
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38. The Broad-lined Ic Supernova ZTF18aaqjovh (SN 2018bvw): An Optically-discovered Engine-driven Supernova Candidate with Luminous Radio Emission
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Ho, Anna Y. Q., Corsi, Alessandra, Cenko, S. Bradley, Taddia, Francesco, Kulkarni, S. R., Adams, Scott, De, Kishalay, Dekany, Richard, Frederiks, Dmitry D., Fremling, Christoffer, Golkhou, V. Zach, Kupfer, Thomas, Laher, Russ R., Mahabal, Ashish, Masci, Frank J., Miller, Adam A., Neill, James D., Reiley, Daniel, Riddle, Reed, Ridnaia, Anna, Rusholme, Ben, Sharma, Yashvi, Sollerman, Jesper, Soumagnac, Maayane T., Svinkin, Dmitry S., and Shupe, David L.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present ZTF18aaqjovh (SN 2018bvw), a high-velocity ("broad-lined") stripped-envelope (Type Ic) supernova (Ic-BL SN) discovered in the Zwicky Transient Facility one-day cadence survey. ZTF18aaqjovh shares a number of features in common with engine-driven explosions: the photospheric velocity and the shape of the optical light curve are very similar to that of the Type Ic-BL SN 1998bw, which was associated with a low-luminosity gamma-ray burst (LLGRB) and had relativistic ejecta. However, the radio luminosity of ZTF18aaqjovh is almost two orders of magnitude fainter than that of SN 1998bw at the same velocity phase, and the shock velocity is at most mildly relativistic (v=0.06-0.4c). A search of high-energy catalogs reveals no compelling GRB counterpart to ZTF18aaqjovh, and the limit on the prompt GRB luminosity of $L_{\gamma,\mathrm{iso}} \approx 1.6 \times 10^{48}$ erg/sec excludes a classical GRB but not an LLGRB. Altogether, ZTF18aaqjovh represents another transition event between engine-driven SNe associated with GRBs and "ordinary" Ic-BL SNe., Comment: 18 pages, 8 figures. Accepted to the Astrophysical Journal on 2 March 2020. Revised from proofs on 4 Apr 2020
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- 2019
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39. Palomar Gattini-IR: Survey overview, data processing system, on-sky performance and first results
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De, Kishalay, Hankins, Matthew J., Kasliwal, Mansi M., Moore, Anna M., Ofek, Eran O., Adams, Scott M., Ashley, Michael C. B., Babul, Aliya-Nur, Bagdasaryan, Ashot, Burdge, Kevin B., Burnham, Jill, Dekany, Richard G., Declacroix, Alexander, Galla, Antony, Greffe, Tim, Hale, David, Jencson, Jacob E., Lau, Ryan M., Mahabal, Ashish, McKenna, Daniel, Sharma, Manasi, Shopbell, Patrick L., Smith, Roger M., Soon, Jamie, Sokoloski, Jennifer, Soria, Roberto, and Travouillon, Tony
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
(Abridged) Palomar Gattini-IR is a new wide-field, near-infrared robotic time domain survey operating at Palomar Observatory. Using a 30 cm telescope mounted with a H2RG detector, Gattini-IR achieves a field of view of 25 sq. deg. with a pixel scale of 8.7" in J-band. Here, we describe the system design, survey operations, data processing system and on-sky performance of Palomar Gattini-IR. As a part of the nominal survey, Gattini-IR scans $\approx 7500$ square degrees of the sky every night to a median 5$\sigma$ depth of $15.7$ AB mag outside the Galactic plane. The survey covers $\approx 15000$ square degrees of the sky visible from Palomar with a median cadence of 2 days. A real-time data processing system produces stacked science images from dithered raw images taken on sky, together with PSF-fit source catalogs and transient candidates identified from subtractions within a median delay of $\approx 4$ hours from the time of observation. The calibrated data products achieve an astrometric accuracy (RMS) of $\approx 0.7$" with respect to Gaia DR2 for sources with S/N $> 10$, and better than $\approx 0.35$" for sources brighter than $\approx 12$ Vega mag. The photometric accuracy (RMS) achieved in the PSF-fit source catalogs is better than $\approx 3$% for sources brighter than $\approx 12$ Vega mag, as calibrated against the 2MASS catalog. With a field of view $\approx 40\times$ larger than any other existing near infrared imaging instrument, Gattini-IR is probing the reddest and dustiest transients in the local universe such as dust obscured supernovae in nearby galaxies, novae behind large columns of extinction within the galaxy, reddened micro-lensing events in the Galactic plane and variability from cool and dust obscured stars. We present results from transients and variables identified since the start of the commissioning period., Comment: 35 pages, 29 figures. Submitted to PASP
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- 2019
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40. Online Dissolved Gas Analysis (DGA) Monitoring System
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Deng, Xianda, Thomas, Kyle, Huang, Huiying, Adams, Scott P, and Liu, Hesen
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Electrical Engineering and Systems Science - Signal Processing ,Electrical Engineering and Systems Science - Systems and Control - Abstract
Transformers are critical assets in power systems and transformer failures can cause asset damage, customer outages, and safety concerns. Dominion Energy has a sophisticated monitoring process for the transformers. One of the most cost-efficient, convenient and practical transformer monitoring methods in industry is Dissolved Gas Analysis(DGA). Leveraging new technology, on-line transformer monitoring equipment is able to measure samples automatically. The challenges of unstable sampling measurements and contradicted analysis results for DGA are discussed in this paper. To provide further insight of transformer health and support a new transformer monitoring process in Dominion Energy, a DGA monitoring system is proposed. The DGA analysis methods used in the monitoring system are selected based on laboratory verification results from Dominion Energy. After derive the thresholds from IEEE standard, the solution of the proposed monitoring system and test results are presented. In the end, a historical transformer failure case in Dominion was analyzed and the results indicate the monitoring system can provide prescient information and sufficient supplemental report for making operational decisions., Comment: 9 pages
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- 2019
41. Missing Red Supergiants and Carbon Burning
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Sukhbold, Tuguldur and Adams, Scott
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Recent studies on direct imaging of Type II core-collapse supernova progenitors indicate a possible threshold around $M_{\rm ZAMS}\sim 16-20$ M$_\odot$, where red supergiants with larger birth masses do not appear to result in supernova explosions and instead implode directly into a black hole. In this study we argue that it is not a coincidence that this threshold closely matches the critical transition of central Carbon burning in massive stars from the convective to radiative regime. In lighter stars, Carbon burns convectively in the center and result in compact final presupernova cores that are likely to result in explosions, while in heavier stars after the transition, it burns as a radiative flame and the stellar cores become significantly harder to explode. Using the KEPLER code we demonstrate the sensitivity of this transition to the rate of $^{12}$C$(\alpha,\gamma)^{16}$O reaction and the overshoot mixing efficiency, and we argue that the upper mass limit of exploding red supergiants could be employed to constrain uncertain input physics of massive stellar evolution calculations. The initial mass corresponding to the central Carbon burning transition range from 14 to 26 M$_\odot$ in recently published models from various groups and codes, and only a few are in agreement with the estimates inferred from direct imaging studies., Comment: submitted to MNRAS
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- 2019
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42. Uncovering Red and Dusty Ultraluminous X-ray Sources with Spitzer
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Lau, Ryan M., Heida, Marianne, Walton, Dominic J., Kasliwal, Mansi M., Adams, Scott M., Cody, Ann Marie, De, Kishalay, Gehrz, Robert D., Furst, Felix, Jencson, Jacob E., Kennea, jamie A., and Masci, Frank
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present a mid-infrared (IR) sample study of nearby ultraluminous X-ray sources (ULXs) using multi-epoch observations with the Infrared Array Camera (IRAC) on the Spitzer Space Telescope. Spitzer/IRAC observations taken after 2014 were obtained as part of the Spitzer Infrared Intensive Transients Survey (SPIRITS). Our sample includes 96 ULXs located within 10 Mpc. Of the 96~ULXs, 12 have candidate counterparts consistent with absolute mid-IR magnitudes of supergiants, and 16 counterparts exceeded the mid-IR brightness of single supergiants and are thus more consistent with star clusters or non-ULX background active galactic nuclei (AGN). The supergiant candidate counterparts exhibit a bi-modal color distribution in a Spitzer/IRAC color-magnitude diagram, where "red" and "blue" ULXs fall in IRAC colors $[3.6] - [4.5]\sim0.7$ and $[3.6] - [4.5]\sim0.0$, respectively. The mid-IR colors and absolute magnitudes of 4 "red" and 5 "blue" ULXs are consistent with that of supergiant B[e] (sgB[e]) and red supergiant (RSG) stars, respectively. While "blue", RSG-like mid-IR ULX counterparts likely host RSG mass donors, we propose the "red" counterparts are ULXs exhibiting the "B[e] phenomenon'' rather than hosts of sgB[e] mass donors. We show that the mid-IR excess from the "red" ULXs is likely due to thermal emission from circumstellar or circumbinary dust. Using dust as a probe for total mass, we estimate mass-loss rates of $\dot{M}\sim1\times10^{-4}$ M$_\odot$ yr$^{-1}$ in dust-forming outflows of red ULXs. Based on the transient mid-IR behavior and its relatively flat spectral index, $\alpha=-0.19\pm0.1$, we suggest that the mid-IR emission from Holmberg IX X-1 originates from a variable jet., Comment: 40 pages, 11 figures, accepted for publication in ApJ
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- 2019
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43. Discovery of an intermediate-luminosity red transient in M51 and its likely dust-obscured, infrared-variable progenitor
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Jencson, Jacob E., Adams, Scott M., Bond, Howard E., van Dyk, Schuyler D., Kasliwal, Mansi M., Bally, John, Blagorodnova, Nadejda, De, Kishalay, Fremling, Christoffer, Yao, Yuhan, Fruchter, Andrew, Rubin, David, Barbarino, Cristina, Sollerman, Jesper, Miller, Adam A., Hicks, Erin K. S., Malkan, Matthew A., Andreoni, Igor, Bellm, Eric C., Buchheim, Robert, Dekany, Richard, Feeney, Michael, Frederick, Sara, Gal-Yam, Avishay, Gehrz, Robert D., Giomi, Matteo, Graham, Matthew J., Green, Wayne, Hale, David, Hankins, Matthew J., Hanson, Mark, Helou, George, Ho, Anna Y. Q., Hung, T., Jurić, Mario, Kendurkar, Malhar R., Kulkarni, S. R., Lau, Ryan M., Masci, Frank J., Neill, James D., Quin, Kevin, Riddle, Reed L., Rusholme, Ben, Sims, Forrest, Smith, Nathan, Smith, Roger M., Soumagnac, Maayane T., Tachibana, Yutaro, Tinyanont, Samaporn, Walters, Richard, Watson, Stanley, and Williams, Robert E.
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Astrophysics - Solar and Stellar Astrophysics - Abstract
We present the discovery of an optical transient (OT) in Messier 51, designated M51 OT2019-1 (also ZTF19aadyppr, AT 2019abn, ATLAS19bzl), by the Zwicky Transient Facility (ZTF). The OT rose over 15 days to an observed luminosity of $M_r=-13$ (${\nu}L_{\nu}=9\times10^6~L_{\odot}$), in the luminosity gap between novae and typical supernovae (SNe). Spectra during the outburst show a red continuum, Balmer emission with a velocity width of $\approx400$ km s$^{-1}$, Ca II and [Ca II] emission, and absorption features characteristic of an F-type supergiant. The spectra and multiband light curves are similar to the so-called "SN impostors" and intermediate-luminosity red transients (ILRTs). We directly identify the likely progenitor in archival Spitzer Space Telescope imaging with a $4.5~\mu$m luminosity of $M_{[4.5]}\approx-12.2$ and a $[3.6]-[4.5]$ color redder than 0.74 mag, similar to those of the prototype ILRTs SN 2008S and NGC 300 OT2008-1. Intensive monitoring of M51 with Spitzer further reveals evidence for variability of the progenitor candidate at [4.5] in the years before the OT. The progenitor is not detected in pre-outburst Hubble Space Telescope optical and near-IR images. The optical colors during outburst combined with spectroscopic temperature constraints imply a higher reddening of $E(B-V)\approx0.7$ mag and higher intrinsic luminosity of $M_r\approx-14.9$ (${\nu}L_{\nu}=5.3\times10^7~L_{\odot}$) near peak than seen in previous ILRT candidates. Moreover, the extinction estimate is higher on the rise than on the plateau, suggestive of an extended phase of circumstellar dust destruction. These results, enabled by the early discovery of M51 OT2019-1 and extensive pre-outburst archival coverage, offer new clues about the debated origins of ILRTs and may challenge the hypothesis that they arise from the electron-capture induced collapse of extreme asymptotic giant branch stars., Comment: 21 pages, 5 figures, published in ApJL
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- 2019
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44. The Dynamic Infrared Sky
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Kasliwal, Mansi M., Adams, Scott, Andreoni, Igor, Ashley, Michael, Blagorodnova, Nadia, De, Kishalay, Frostig, Danielle, Furesz, Gabor, Jencson, Jacob, Hankins, Matthew, Helou, George, Lau, Ryan, Moore, Anna, Ofek, Eran, Simcoe, Rob, Sokoloski, Jennifer, Soon, Jamie, Tinyanont, Samaporn, and Travouillon, Tony
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Opening up the dynamic infrared sky for systematic time-domain exploration would yield many scientific advances. Multi-messenger pursuits such as localizing gravitational waves from neutron star mergers and quantifying the nucleosynthetic yields require the infrared. Another multi-messenger endeavor that needs infrared surveyors is the study of the much-awaited supernova in our own Milky Way. Understanding shocks in novae, true rates of supernovae and stellar mergers are some other examples of stellar evolution and high energy physics wherein the answers are buried in the infrared. We discuss some of the challenges in the infrared and pathfinders to overcome them. We conclude with recommendations on both infrared discovery engines and infrared follow-up machines that would enable this field to flourish in the next decade., Comment: Astro2020 Science White Paper for Decadal Survey
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- 2019
45. Physical activity and physical fitness assessments in adolescents and young adults diagnosed with cancer: a scoping review
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Caru, Maxime, Wurz, Amanda, Brunet, Jennifer, Barb, Emily D., Adams, Scott C., Roth, Michael E., Winters-Stone, Kerri, Fidler-Benaoudia, Miranda M., Dandekar, Smita, Ness, Kirsten K., Culos-Reed, S. Nicole, Schulte, Fiona, Rao, Pooja, Mizrahi, David, Swartz, Maria Chang, Smith, Marlie, Valle, Carmina G., Kadan-Lottick, Nina S., Dieli-Conwright, Christina M., and Schmitz, Kathryn H.
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- 2023
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46. Closed-loop control systems for pumps used in portable analytical systems
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Naz, Suleman A., Huynh, Van Thanh, Doeven, Egan H., Adams, Scott, Kouzani, Abbas, and Guijt, Rosanne M.
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- 2023
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47. Self-Supervised Leaf Segmentation under Complex Lighting Conditions
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Lin, Xufeng, Li, Chang-Tsun, Adams, Scott, Kouzani, Abbas Z., Jiang, Richard, He, Ligang, Hu, Yongjian, Vernon, Michael, Doeven, Egan, Webb, Lawrence, Mcclellan, Todd, and Guskich, Adam
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- 2023
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48. How a data driven approach will achieve operational excellence
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Adams, Scott
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- 2024
49. Speech Rate Mediated Vowel and Stop Voicing Distinctiveness in Parkinson's Disease
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Knowles, Thea, Adams, Scott G., and Jog, Mandar
- Abstract
Purpose: The purpose of this study was to quantify changes in acoustic distinctiveness in two groups of talkers with Parkinson's disease as they modify across a wide range of speaking rates. Method: People with Parkinson's disease with and without deep brain stimulation and older healthy controls read 24 carrier phrases at different speech rates. Target nonsense words in the carrier phrases were designed to elicit stop consonants and corner vowels. Participants spoke at seven self-selected speech rates from very slow to very fast, elicited via magnitude production. Speech rate was measured in absolute words per minute and as a proportion of each talker's habitual rate. Measures of segmental distinctiveness included a temporal consonant measure, namely, voice onset time, and a spectral vowel measure, namely, vowel articulation index. Results: All talkers successfully modified their rate of speech from slow to fast. Talkers with Parkinson's disease and deep brain stimulation demonstrated greater baseline speech impairment and produced smaller proportional changes at the fast end of the continuum. Increasingly slower speaking rates were associated with increased temporal contrasts (voice onset time) but not spectral contrasts (vowel articulation). Faster speech was associated with decreased contrasts in both domains. Talkers with deep brain stimulation demonstrated more aberrant productions across all speaking rates. Conclusions: Findings suggest that temporal and spectral segmental distinctiveness are asymmetrically affected by speaking rate modifications in Parkinson's disease. Talkers with deep brain stimulation warrant further investigation with regard to speech changes they make as they adjust their speaking rate.
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- 2021
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50. The Zwicky Transient Facility: System Overview, Performance, and First Results
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Bellm, Eric C., Kulkarni, Shrinivas R., Graham, Matthew J., Dekany, Richard, Smith, Roger M., Riddle, Reed, Masci, Frank J., Helou, George, Prince, Thomas A., Adams, Scott M., Barbarino, C., Barlow, Tom, Bauer, James, Beck, Ron, Belicki, Justin, Biswas, Rahul, Blagorodnova, Nadejda, Bodewits, Dennis, Bolin, Bryce, Brinnel, Valery, Brooke, Tim, Bue, Brian, Bulla, Mattia, Burruss, Rick, Cenko, S. Bradley, Chang, Chan-Kao, Connolly, Andrew, Coughlin, Michael, Cromer, John, Cunningham, Virginia, De, Kishalay, Delacroix, Alex, Desai, Vandana, Duev, Dmitry A., Eadie, Gwendolyn, Farnham, Tony L., Feeney, Michael, Feindt, Ulrich, Flynn, David, Franckowiak, Anna, Frederick, S., Fremling, C., Gal-Yam, Avishay, Gezari, Suvi, Giomi, Matteo, Goldstein, Daniel A., Golkhou, V. Zach, Goobar, Ariel, Groom, Steven, Hacopians, Eugean, Hale, David, Henning, John, Ho, Anna Y. Q., Hover, David, Howell, Justin, Hung, Tiara, Huppenkothen, Daniela, Imel, David, Ip, Wing-Huen, Ivezić, Željko, Jackson, Edward, Jones, Lynne, Juric, Mario, Kasliwal, Mansi M., Kaspi, S., Kaye, Stephen, Kelley, Michael S. P., Kowalski, Marek, Kramer, Emily, Kupfer, Thomas, Landry, Walter, Laher, Russ R., Lee, Chien-De, Lin, Hsing Wen, Lin, Zhong-Yi, Lunnan, Ragnhild, Mahabal, Ashish, Mao, Peter, Miller, Adam A., Monkewitz, Serge, Murphy, Patrick, Ngeow, Chow-Choong, Nordin, Jakob, Nugent, Peter, Ofek, Eran, Patterson, Maria T., Penprase, Bryan, Porter, Michael, Rauch, Ludwig, Rebbapragada, Umaa, Reiley, Dan, Rigault, Mickael, Rodriguez, Hector, van Roestel, Jan, Rusholme, Ben, van Santen, Jakob, Schulze, S., Shupe, David L., Singer, Leo P., Soumagnac, Maayane T., Stein, Robert, Surace, Jason, Sollerman, Jesper, Szkody, Paula, Taddia, F., Terek, Scott, Van Sistine, Angela, van Velzen, Sjoert, Vestrand, W. Thomas, Walters, Richard, Ward, Charlotte, Ye, Quan-Zhi, Yu, Po-Chieh, Yan, Lin, and Zolkower, Jeffry
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The Zwicky Transient Facility (ZTF) is a new optical time-domain survey that uses the Palomar 48-inch Schmidt telescope. A custom-built wide-field camera provides a 47 deg$^2$ field of view and 8 second readout time, yielding more than an order of magnitude improvement in survey speed relative to its predecessor survey, the Palomar Transient Factory (PTF). We describe the design and implementation of the camera and observing system. The ZTF data system at the Infrared Processing and Analysis Center provides near-real-time reduction to identify moving and varying objects. We outline the analysis pipelines, data products, and associated archive. Finally, we present on-sky performance analysis and first scientific results from commissioning and the early survey. ZTF's public alert stream will serve as a useful precursor for that of the Large Synoptic Survey Telescope., Comment: Published in PASP Focus Issue on the Zwicky Transient Facility (https://dx.doi.org/10.1088/1538-3873/aaecbe). 21 Pages, 12 Figures
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- 2019
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