382 results on '"Acton, Thomas B."'
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2. A hybrid NMR/SAXS‐based approach for discriminating oligomeric protein interfaces using Rosetta
3. Structural and Biochemical Studies Identify Tobacco SABP2 as a Methyl Salicylate Esterase and Implicate It in Plant Innate Immunity
4. Structural genomics is the largest contributor of novel structural leverage
5. Protocol for production and purification of SARS-CoV-2 3CLpro
6. The RAS-Binding Domain of Human BRAF Protein Serine/Threonine Kinase Exhibits Allosteric Conformational Changes upon Binding HRAS
7. Crystal Structures of Malonyl-Coenzyme A Decarboxylase Provide Insights into Its Catalytic Mechanism and Disease-Causing Mutations
8. Codon influence on protein expression in E. coli correlates with mRNA levels
9. High-Throughput Production of Proteins in E. coli for Structural Studies
10. The second round of Critical Assessment of Automated Structure Determination of Proteins by NMR: CASD-NMR-2013
11. Polypeptide backbone, Cβ and methyl group resonance assignments of the 24 kDa plectin repeat domain 6 from human protein plectin
12. Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples
13. Novel C-terminal Motif within Sec7 Domain of Guanine Nucleotide Exchange Factors Regulates ADP-ribosylation Factor (ARF) Binding and Activation
14. Molecular Insights into Substrate Recognition and Catalysis by Tryptophan 2,3-Dioxygenase
15. Solution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network
16. Solution NMR structures of immunoglobulin-like domains 7 and 12 from obscurin-like protein 1 contribute to the structural coverage of the human cancer protein interaction network
17. The high-throughput protein sample production platform of the Northeast Structural Genomics Consortium
18. Structural Basis of O6-Alkylguanine Recognition by a Bacterial Alkyltransferase-like DNA Repair Protein
19. Structure function characterization of SARS CoV2 proteases for COVID19 antiviral development
20. A community resource of experimental data for NMR / X-ray crystal structure pairs
21. Solution NMR structure of CD1104B from pathogenic Clostridium difficile reveals a distinct α-helical architecture and provides first structural representative of protein domain family PF14203
22. Solution NMR structures provide first structural coverage of the large protein domain family PF08369 and complementary structural coverage of dark operative protochlorophyllide oxidoreductase complexes
23. Solution NMR structure of the helicase associated domain BVU_0683(627–691) from Bacteroides vulgatus provides first structural coverage for protein domain family PF03457 and indicates domain binding to DNA
24. Crystal structure of a catalytically active GG(D/E)EF diguanylate cyclase domain from Marinobacter aquaeolei with bound c-di-GMP product
25. Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267
26. Solution NMR and X-ray crystal structures of Pseudomonas syringae Pspto_3016 from protein domain family PF04237 (DUF419) adopt a “double wing” DNA binding motif
27. Three structural representatives of the PF06855 protein domain family from Staphyloccocus aureus and Bacillus subtilis have SAM domain-like folds and different functions
28. Solution NMR structures reveal unique homodimer formation by a winged helix-turn-helix motif and provide first structures for protein domain family PF10771
29. Solution NMR structures reveal a distinct architecture and provide first structures for protein domain family PF04536
30. Principles for designing ideal protein structures
31. Solution NMR structure of MED25(391–543) comprising the activator-interacting domain (ACID) of human mediator subunit 25
32. Solution NMR structure of Dsy0195 homodimer from Desulfitobacterium hafniense: first structure representative of the YabP domain family of proteins involved in spore coat assembly
33. Solution NMR and X-ray crystal structures of membrane-associated Lipoprotein-17 domain reveal a novel fold
34. Molecular Insights into the Biosynthesis of the F420 Coenzyme
35. Engineering of a wheat germ expression system to provide compatibility with a high throughput pET-based cloning platform
36. A microscale protein NMR sample screening pipeline
37. 1H, 13C, and 15N NMR assignments for the Bacillus subtilis yndB START domain
38. Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila
39. Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins
40. Functional insights from structural genomics
41. Structural and Functional Studies of the Abundant Tegument Protein ORF52 from Murine Gammaherpesvirus 68
42. DisMeta: A Meta Server for Construct Design and Optimization
43. Primer Prim'r: A web based server for automated primer design
44. Preparation of Protein Samples for NMR Structure, Function, and Small-Molecule Screening Studies
45. Crystal Structures of Two Bacterial 3-Hydroxy-3-methylglutaryl-CoA Lyases Suggest a Common Catalytic Mechanism among a Family of TIM Barrel Metalloenzymes Cleaving Carbon-Carbon Bonds
46. Structures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein domain family DUF2128 and expand the single-stranded DNA-binding domain proteome
47. Hepatitis C Virus Drugs Simeprevir and Grazoprevir Synergize with Remdesivir to Suppress SARS-CoV-2 Replication in Cell Culture
48. Structural and Functional Evidence for Bacillus subtilis PaiA as a Novel N1-Spermidine/Spermine Acetyltransferase
49. Robotic Cloning and Protein Production Platform of the Northeast Structural Genomics Consortium
50. Crystal structure of AGR_C_4470p from Agrobacterium tumefaciens
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