15 results on '"Acone, Benedetto"'
Search Results
2. Selection of antiseizure medications for first add-on use: A consensus paper
- Author
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Gambardella, Antonio, Tinuper, Paolo, Acone, Benedetto, Bonanni, Paolo, Coppola, Giangennaro, and Perucca, Emilio
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- 2021
- Full Text
- View/download PDF
3. Perampanel as first add-on antiseizure medication: Italian consensus clinical practice statements
- Author
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Bonanni, Paolo, Gambardella, Antonio, Tinuper, Paolo, Acone, Benedetto, Perucca, Emilio, and Coppola, Giangennaro
- Published
- 2021
- Full Text
- View/download PDF
4. How to Improve Effectiveness and Adherence to Antihypertensive Drug Therapy: Central Role of Dihydropyridinic Calcium Channel Blockers in Hypertension
- Author
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Tocci, Giuliano, Desideri, Giovambattista, Roca, Elisa, Calcullo, Calogero, Crippa, Massimo, De Luca, Nicola, Gaudio, Giovanni Vincenzo, Lonati, Laura Maria, Orselli, Leo, Scuteri, Angelo, Vulpis, Vito, Acone, Benedetto, Zaninelli, Augusto, and on behalf of the THYPERevolution Steering Committee
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- 2018
- Full Text
- View/download PDF
5. Pain assessment and management in Italian Haemophilia Centres
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Di Minno, Matteo N D, Santoro, Cristina, Corcione, Antonio, Di Minno, Giovanni, Martinelli, Marco, Mancuso, Maria E, Acone, Benedetto, Molinari, Angelo C, Passeri, Emilio V, Rocino, Angiola, Santoro, Rita C, Tagliaferri, Annarita, Mattia, Consalvo, Agostini, Paola, Andreoli, Ernesto, Ambaglio, Chiara, Arancio, Fabiola, Aru, Brigida, Baldacci, Erminia, Belfiore, Antonella, Bernasconi, Sayla, Biasoli, Chiara, Borchiellini, Alessandra, Brunetti, Gregorio, Cerbone, Annamaria, Caimi, Teresa, Cantori, Isabella, Coluccia, Antonella, Contino, Laura, Coppetelli, Ugo, Costanzi, Matteo, Cultrera, Dorina, De Cristofaro, Raimondo, Delios, Grazia, Di Gennaro, Leonardo, Di Gregorio, Patrizia, Ettorre, Cosimo Pietro, Fasulo, Rosamaria, Feola, Giulio, Ferretti, Antonietta, Franchini, Massimo, Frizziero, Antonio, Galletti, Lisa, Giuffrida, Gaetano, Giuffrida, Annachiara, Iannaccaro, Piergiorgio, Lassandro, Giuseppe, Linari, Silvia, Lione, Aurora, Lombardo, Rita, Luciani, Matteo, Macchi, Silvia, Maestrini, Giacomo, Malcangi, Giuseppe, Malizia, Raniero, Margaglione, Maurizio, Marietta, Marco, Marino, Renato, Massoud, Michela, Napolitano, Mariasanta, Nichele, Ilaria, Notarangelo, Lucia Dora, Pagano, Cinzia, Pasta, Gianluigi, Pollio, Berardino, Quintavalle, Gabriele, Ranalli, Paola, Raso, Simona, Ricca, Irene, Schiavoni, Mario, Schiavulli, Michele, Sottilotta, Gianluca, Todisco, Angela, Zanon, Ezio, Di Minno, Matteo N D, Santoro, Cristina, Corcione, Antonio, Di Minno, Giovanni, Martinelli, Marco, Mancuso, Maria E, Acone, Benedetto, Molinari, Angelo C, Passeri, Emilio V, Rocino, Angiola, Santoro, Rita C, Tagliaferri, Annarita, Mattia, Consalvo, Agostini, Paola, Andreoli, Ernesto, Ambaglio, Chiara, Arancio, Fabiola, Aru, Brigida, Baldacci, Erminia, Belfiore, Antonella, Bernasconi, Sayla, Biasoli, Chiara, Borchiellini, Alessandra, Brunetti, Gregorio, Cerbone, Annamaria, Caimi, Teresa, Cantori, Isabella, Coluccia, Antonella, Contino, Laura, Coppetelli, Ugo, Costanzi, Matteo, Cultrera, Dorina, De Cristofaro, Raimondo, Delios, Grazia, Di Gennaro, Leonardo, Di Gregorio, Patrizia, Ettorre, Cosimo Pietro, Fasulo, Rosamaria, Feola, Giulio, Ferretti, Antonietta, Franchini, Massimo, Frizziero, Antonio, Galletti, Lisa, Giuffrida, Gaetano, Giuffrida, Annachiara, Iannaccaro, Piergiorgio, Lassandro, Giuseppe, Linari, Silvia, Lione, Aurora, Lombardo, Rita, Luciani, Matteo, Macchi, Silvia, Maestrini, Giacomo, Malcangi, Giuseppe, Malizia, Raniero, Margaglione, Maurizio, Marietta, Marco, Marino, Renato, Massoud, Michela, Napolitano, Mariasanta, Nichele, Ilaria, Notarangelo, Lucia Dora, Pagano, Cinzia, Pasta, Gianluigi, Pollio, Berardino, Quintavalle, Gabriele, Ranalli, Paola, Raso, Simona, Ricca, Irene, Schiavoni, Mario, Schiavulli, Michele, Sottilotta, Gianluca, Todisco, Angela, and Zanon, Ezio
- Subjects
Factor IX ,Italy ,Humans ,Pain Management ,pain heamophilia ,Hemophilia A ,blood coagulation disorders, haemophilia, pain perception, pain management, surveys ,Haemostasis and Thrombosis ,Pain Measurement - Abstract
BACKGROUND: Although the widespread use of factor VIII/IX replacement therapy has significantly reduced the severity of arthropathy in persons with haemophilia (PWH), some develop degenerative joint changes, associated with significant pain. The aim of this survey was to investigate the management and perception of pain among Italian physicians who treat PWH. MATERIALS AND METHODS: Between September and October 2017, a questionnaire was distributed to 35 Italian haemophilia treatment centres (60 physicians). RESULTS: Fifty-three haemophilia specialists completed the survey. We found that there was good agreement (98.1%) on the need to investigate pain at each clinical visit, but there was heterogeneity in the opinions of haemophilia specialists with regards to the availability of validated guidelines (35.8%) and whether pain specialists should be a part of the comprehensive care team in daily clinical practice (58.5%). Haemophilia specialists also agreed pain should be evaluated using a rating scale validated in PWH (88.7%). Pain was mainly managed by the haemophilia specialists themselves, supported by a physiatrist and physiotherapist, while a pain specialist was only involved in 26.4% of cases. The combination of paracetamol with tramadol or codeine was the most common first-line treatment, while cyclo-oxygenase-2 inhibitors, non-steroidal anti-inflammatory drugs, and opioids were less commonly used. DISCUSSION: There are some unmet needs in Italy regarding pain management for PWH and the management of pain in these patients by haemophilia specialists. There is a lack of evidence-based guidelines for these specialists to use, as well as a reluctance to involve pain specialists. The lack of spontaneous reporting of pain by PWH, despite using pain relief, highlights the need for clinicians to actively ask patients about any pain they may be experiencing.
- Published
- 2021
6. Improving assessment and management of pain in hemophilia: an Italian Delphi consensus statement
- Author
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Santoro, Cristina, primary, Di Minno, Matteo Nicola Dario, additional, Corcione, Antonio, additional, Di Minno, Giovanni, additional, Martinelli, Marco, additional, Mancuso, Maria Elisa, additional, Acone, Benedetto, additional, Molinari, Angelo Claudio, additional, Passeri, Emilio Valter, additional, Rocino, Angiola, additional, Santoro, Rita Carlotta, additional, Tagliaferri, Annarita, additional, and Mattia, Consalvo, additional
- Published
- 2022
- Full Text
- View/download PDF
7. Additional file 1 of Perampanel as first add-on antiseizure medication: Italian consensus clinical practice statements
- Author
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Bonanni, Paolo, Gambardella, Antonio, Tinuper, Paolo, Acone, Benedetto, Perucca, Emilio, and Coppola, Giangennaro
- Abstract
Additional file 1: Supplementary Table 1. General statements and statements addressing efficacy and safety issues, with associated ratings for relevance and level of agreement. Supplementary Table 2. List of statements addressing potential implications of drug interactions, mechanism of action and adherence, with associated ratings for relevance and level of agreement. Supplementary Table 3. List of statements addressing potential implications of ease of use and other factors specific for the Italian setting, with associated ratings for relevance and level of agreement.
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- 2021
- Full Text
- View/download PDF
8. SLAM Project - Second-Level Diagnostic Assessment: Multidisciplinary approach to HIV Patients
- Author
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Di Biagio, A, Bonfanti, P, Madeddu, G, De Socio, G, Maggi, P, Vichi, F, Martinelli, C, Menzaghi, B, Orofino, G, Squillace, N, Ricci, E, Acone, B, Quirino, T, Di Biagio, Antonio, Bonfanti, Paolo, Madeddu, Giordano, De Socio, Giuseppe, Maggi, Paolo, Vichi, Francesca, Martinelli, Canio, Menzaghi, Barbara, Orofino, Giancarlo, Squillace, Nicola, Ricci, Elena, Acone, Benedetto, Quirino, Tiziana, Di Biagio, A, Bonfanti, P, Madeddu, G, De Socio, G, Maggi, P, Vichi, F, Martinelli, C, Menzaghi, B, Orofino, G, Squillace, N, Ricci, E, Acone, B, Quirino, T, Di Biagio, Antonio, Bonfanti, Paolo, Madeddu, Giordano, De Socio, Giuseppe, Maggi, Paolo, Vichi, Francesca, Martinelli, Canio, Menzaghi, Barbara, Orofino, Giancarlo, Squillace, Nicola, Ricci, Elena, Acone, Benedetto, and Quirino, Tiziana
- Abstract
The aim of the study is to propose a multidimensional second-level diagnostic assessment to allow follow- up in the event physicians observe the presence of risk factors and/or active co-morbidities in HIV-infected patients. To develop our proposal, we chose the Delphi method that has been used for about 30 years in the healthcare field. The CISAI Group (Coordinamento Italiano per lo Studio dell'Allergia in Infezione da HIV) conducted this study. The first phase of the study provided identification of the questionnaire for second-level diagnostic assessment of HIV-infected patients. From March to July 2018 the questionnaire was submitted to 48 experts from 10 Italian HIV-dedicated sites. The questionnaire consisted of 102 items divided into 7 survey areas. The results can be summarized as follows: infectious disease diagnostics, 18 items reached agreement in 9 cases; osteoporosis diagnostics 12 items with 3 agreements; metabolic and cardiovascular diagnostics 13 items with 4 agreements; nephrology diagnostics 19 items with 8 agreements; hepatology diagnostics 12 items with 9 agreements; CNS diagnostics: 18 items with 7 agreements; psychological diagnostics and quality of life assessment (QoL) 10 items with no agreement. If these considerations are confirmed in required discussions and in-depth analyses, they will be able to produce an important indication in the drafting of national guidelines.
- Published
- 2019
9. Pain assessment and management in Italian Haemophilia Centres.
- Author
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Di Minno, Matteo N. D., Santoro, Cristina, Corcione, Antonio, Di Minno, Giovanni, Martinelli, Marco, Mancuso, Maria E., Acone, Benedetto, Molinari, Angelo C., Passeri, Emilio V., Rocino, Angiola, Santoro, Rita C., Tagliaferri, Annarita, and Mattia, Consalvo
- Published
- 2021
- Full Text
- View/download PDF
10. Il metodo Delphi: la metodologia e la sua applicazione
- Author
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Acone, Benedetto, primary and Urbani, Alessandro, primary
- Published
- 2018
- Full Text
- View/download PDF
11. Delphi poll to assess consensus on issues influencing long-term adherence to treatments in cystic fibrosis among Italian health care professionals
- Author
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Colombo,Carla, Catastini,Paola, Brivio,Anna, Acone,Benedetto, Dang,Patricia, Quattrucci,Serena, Colombo,Carla, Catastini,Paola, Brivio,Anna, Acone,Benedetto, Dang,Patricia, and Quattrucci,Serena
- Abstract
Carla Colombo,1 Paola Catastini,2 Anna Brivio,1,3 Benedetto Acone,4 Patricia Dang,5 Serena Quattrucci6 1Cystic Fibrosis Center, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; 2Cystic Fibrosis Regional Center, Anna Meyer Children’s Hospital, Florence, Italy; 3UOC DPS Department for Health Professional, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy; 4Cartesio Solutions S.r.l., Venice, Italy; 5Vertex Pharmaceuticals S.r.l., Rome, Italy; 6Cystic Fibrosis Lazio Regional Center, Pediatrics Department, “Sapienza” University, Rome, Italy Purpose: The aim of this study was to determine the level of consensus among Italian health care professionals (HCPs) regarding factors that influence adherence to cystic fibrosis (CF) treatments.Methods: A Delphi questionnaire with 94 statements of potential factors influencing adherence was developed based on a literature review and in consultation with a board of experts (n=4). This was distributed to a multidisciplinary expert panel of HCPs (n=110) from Italian CF centers. A Likert scale was used to indicate the level of agreement (1= no agreement to 9= maximum agreement) with each statement. Three rounds were distributed to establish a consensus (≥80% of participant ratings within one 3-point region) and, at the third round, assign a ranking to each statement with a high level of agreement (consensus in the 7–9 range) only.Results: Of 110 HCPs (from 31 Italian CF centers who were surveyed), responses were obtained from 85 (77%) in the first, 78 (71%) in the second, and 72 (65%) in the third round. The highest degree of agreement (95.8%) was reached with the statement that the HCP needs to build a relationship with the patient to influence adherence. A high level of agreement was not reached for statements that morbidity an
- Published
- 2018
12. Delphi poll to assess consensus on issues influencing long-term adherence to treatments in cystic fibrosis among Italian health care professionals
- Author
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Colombo, Carla, primary, Catastini, Paola, additional, Brivio, Anna, additional, Acone, Benedetto, additional, Dang, Patricia, additional, and Quattrucci, Serena, additional
- Published
- 2018
- Full Text
- View/download PDF
13. Pain assessment and management in Italian Haemophilia Centres.
- Author
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Di Minno MND, Santoro C, Corcione A, Di Minno G, Martinelli M, Mancuso ME, Acone B, Molinari AC, Passeri EV, Rocino A, Santoro RC, Tagliaferri A, and Mattia C
- Subjects
- Factor IX, Humans, Italy epidemiology, Pain Management, Pain Measurement, Hemophilia A complications, Hemophilia A diagnosis, Hemophilia A epidemiology
- Abstract
Background: Although the widespread use of factor VIII/IX replacement therapy has significantly reduced the severity of arthropathy in persons with haemophilia (PWH), some develop degenerative joint changes, associated with significant pain. The aim of this survey was to investigate the management and perception of pain among Italian physicians who treat PWH., Materials and Methods: Between September and October 2017, a questionnaire was distributed to 35 Italian haemophilia treatment centres (60 physicians)., Results: Fifty-three haemophilia specialists completed the survey. We found that there was good agreement (98.1%) on the need to investigate pain at each clinical visit, but there was heterogeneity in the opinions of haemophilia specialists with regards to the availability of validated guidelines (35.8%) and whether pain specialists should be a part of the comprehensive care team in daily clinical practice (58.5%). Haemophilia specialists also agreed pain should be evaluated using a rating scale validated in PWH (88.7%). Pain was mainly managed by the haemophilia specialists themselves, supported by a physiatrist and physiotherapist, while a pain specialist was only involved in 26.4% of cases. The combination of paracetamol with tramadol or codeine was the most common first-line treatment, while cyclo-oxygenase-2 inhibitors, non-steroidal anti-inflammatory drugs, and opioids were less commonly used., Discussion: There are some unmet needs in Italy regarding pain management for PWH and the management of pain in these patients by haemophilia specialists. There is a lack of evidence-based guidelines for these specialists to use, as well as a reluctance to involve pain specialists. The lack of spontaneous reporting of pain by PWH, despite using pain relief, highlights the need for clinicians to actively ask patients about any pain they may be experiencing.
- Published
- 2021
- Full Text
- View/download PDF
14. SLAM Project - Second-Level Diagnostic Assessment: Multidisciplinary approach to HIV Patients.
- Author
-
Di Biagio A, Bonfanti P, Madeddu G, De Socio G, Maggi P, Vichi F, Martinelli C, Menzaghi B, Orofino G, Squillace N, Ricci E, Acone B, and Quirino T
- Subjects
- Comorbidity, Diagnostic Equipment standards, Humans, Interdisciplinary Communication, Italy, Quality of Life, Risk Factors, Surveys and Questionnaires, Delphi Technique, HIV Infections complications, HIV Infections diagnosis
- Abstract
The aim of the study is to propose a multidimensional second-level diagnostic assessment to allow follow- up in the event physicians observe the presence of risk factors and/or active co-morbidities in HIV-infected patients. To develop our proposal, we chose the Delphi method that has been used for about 30 years in the healthcare field. The CISAI Group (Coordinamento Italiano per lo Studio dell'Allergia in Infezione da HIV) conducted this study. The first phase of the study provided identification of the questionnaire for second-level diagnostic assessment of HIV-infected patients. From March to July 2018 the questionnaire was submitted to 48 experts from 10 Italian HIV-dedicated sites. The questionnaire consisted of 102 items divided into 7 survey areas. The results can be summarized as follows: infectious disease diagnostics, 18 items reached agreement in 9 cases; osteoporosis diagnostics 12 items with 3 agreements; metabolic and cardiovascular diagnostics 13 items with 4 agreements; nephrology diagnostics 19 items with 8 agreements; hepatology diagnostics 12 items with 9 agreements; CNS diagnostics: 18 items with 7 agreements; psychological diagnostics and quality of life assessment (QoL) 10 items with no agreement. If these considerations are confirmed in required discussions and in-depth analyses, they will be able to produce an important indication in the drafting of national guidelines.
- Published
- 2019
15. Managing the long surviving HIV patient: a proposal for a multidimensional first-level diagnostic assessment.
- Author
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Borderi M, Angarano G, Antinori A, Chirianni A, Cinque P, D'Arminio Monforte A, Di Biagio A, Di Perri G, Galli M, Gori A, Lazzarin A, Mussini C, Perno CF, Quirino T, Rizzardini G, Calza L, Viale P, Acone B, and Andreoni M
- Subjects
- Algorithms, Anti-HIV Agents administration & dosage, Comorbidity, Delphi Technique, Humans, Longevity, Quality of Life, Anti-HIV Agents therapeutic use, HIV Infections diagnosis, HIV Infections drug therapy
- Abstract
We propose a multidimensional first-level diagnostic assessment easy to use in routine clinical practice to allow infectious disease specialists to have a general and complete overview of persons living with HIV. Following the Delphi method, articles published from January 1, 2011 on controlled trials, clinical reports and observational studies dealing specifically with HIV and its co-morbidities were selected for review by the authors. Participants in the poll were selected among clinicians and infectious diseases specialists, working in 38 different dedicated HIV centres in Italy. The participants were given access to a website dedicated to the project and received a standardized information package containing a synopsis of the study and a description of the Delphi process and the selected literature. A total of 131 Items were divided into 10 first-level survey areas: anamnesis, objective examination, infectious diseases, osteoporosis diagnosis, metabolic pathologies diagnosis, cardiovascular diagnosis, nephrologic diagnosis, hepatological diagnosis, central nervous system diagnosis, evaluation of quality of life (QoL). This simple and concise first level tool identifies a few areas of multi-organ diagnostic assessment beyond the infectivity area. The identification of these areas will allow us to find shared and validated evaluation procedures with the intent to increase the likelihood of early recognition of patients at risk of comorbidity development, in order to facilitate more effective prevention, thereby reducing the overall impact on the quality of life of patients affected by this chronic illness.
- Published
- 2018
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